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Information on EC 3.4.24.B6 - matrix metalloproteinase-20

for references in articles please use BRENDA:EC3.4.24.B6
preliminary BRENDA-supplied EC number
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EC Tree
     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.24 Metalloendopeptidases
                3.4.24.B6 matrix metalloproteinase-20
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This record set is specific for:
UNIPROT: Q3LRH7
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Word Map
The expected taxonomic range for this enzyme is: Tetrapoda
Reaction Schemes
proteolytic degradation of ameloblastin
proteolytic cleavage of ameloblastin
Synonyms
mmp20, mmp-20, enamelysin, matrix metalloproteinase-20, matrix metalloproteinase 20, enamel protease, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
enamelysin
-
CAS REGISTRY NUMBER
COMMENTARY hide
185766-51-2
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
SwissProt
Manually annotated by BRENDA team
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
minute quantities, 5000fold lower than in 4-day-old first molar tooth buds
Manually annotated by BRENDA team
only in jaw containing the developing tooth buds appreciable levels of the enzyme
Manually annotated by BRENDA team
additional information
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
Q3LRH7_MOUSE
68
0
7370
TrEMBL
-
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
APPLICATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
additional information
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Turk, B.E.; Lee, D.H.; Yamakoshi, Y.; Klingenhoff, A.; Reichenberger, E.; Wright, J.T.; Simmer, J.P.; Komisarof, J.A.; Cantley, L.C.; Bartlett, J.D.
MMP-20 is predominately a tooth-specific enzyme with a deep catalytic pocket that hydrolyzes type V collagen
Biochemistry
45
3863-3874
2006
Homo sapiens, Mus musculus (Q3LRH7), Mus musculus
Manually annotated by BRENDA team