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Adenocarcinoma
Comprehensive analysis of matrix metalloproteinase and tissue inhibitor expression in pancreatic cancer: increased expression of matrix metalloproteinase-7 predicts poor survival.
Adenocarcinoma
Differential expression and origin of membrane-type 1 and 2 matrix metalloproteinases (MT-MMPs) in association with MMP2 activation in injured human livers.
Adenocarcinoma
Induction of membrane-type matrix metalloproteinase 1 (MT1-MMP) expression in human fibroblasts by breast adenocarcinoma cells.
Adenocarcinoma
Membrane type matrix metalloproteinases (MMPs) show differential expression in non-small cell lung cancer (NSCLC) compared to normal lung: correlation of MMP-14 mRNA expression and proteolytic activity.
Adenocarcinoma of Lung
Identification of MMP-15 as an anti-apoptotic factor in cancer cells.
Adenomyosis
Increased invasion activity of endometrial stromal cells and elevated expression of matrix metalloproteinase messenger RNA in the uterine tissues of mice with experimentally induced adenomyosis.
Arthritis, Rheumatoid
Expression of membrane-type matrix metalloproteinases in synovial tissue from patients with rheumatoid arthritis or osteoarthritis.
Arthritis, Rheumatoid
Long noncoding RNA ZFAS1 silencing alleviates rheumatoid arthritis via blocking miR-296-5p-mediated down-regulation of MMP-15.
Brain Neoplasms
Clusterin, an abundant serum factor, is a possible negative regulator of MT6-MMP/MMP-25 produced by neutrophils.
Brain Neoplasms
Differential expression of membrane-type matrix metalloproteinase and its correlation with gelatinase A activation in human malignant brain tumors in vivo and in vitro.
Breast Neoplasms
A membrane-type-1 matrix metalloproteinase (MT1-MMP)-discoidin domain receptor 1 axis regulates collagen-induced apoptosis in breast cancer cells.
Breast Neoplasms
Complex regulation of membrane-type matrix metalloproteinase expression and matrix metalloproteinase-2 activation by concanavalin A in MDA-MB-231 human breast cancer cells.
Breast Neoplasms
Expression of MMPs and TIMPs genes in human breast cancer epithelial cells depends on cell culture conditions and is associated with their invasive potential.
Breast Neoplasms
LncRNA MAFG-AS1 promotes the aggressiveness of breast carcinoma through regulating miR-339-5p/MMP15.
Breast Neoplasms
Membrane-type matrix metalloproteinase (MT-MMP) gene is expressed in stromal cells of human colon, breast, and head and neck carcinomas.
Breast Neoplasms
Molecular cloning of a novel membrane-type matrix metalloproteinase from a human breast carcinoma.
Breast Neoplasms
Protein kinase D1 regulates matrix metalloproteinase expression and inhibits breast cancer cell invasion.
Carcinogenesis
Expression of matrix metalloproteinase 2 (MMP-2), membrane-type 1 MMP and tissue inhibitor of metalloproteinase 2 and activation of proMMP-2 in pancreatic duct adenocarcinomas in hamsters treated with N-nitrosobis(2-oxopropyl)amine.
Carcinogenesis
Matrix metalloproteinases 15 and 19 are stromal regulators of colorectal cancer development from the early stages.
Carcinogenesis
MicroRNA-148a reduces tumorigenesis and increases TRAIL-induced apoptosis in NSCLC.
Carcinogenesis
[Analysis of differential expression genes related to different metastasis potential of adenoid cystic carcinoma using restriction fragments differential display PCR]
Carcinoma
Activation of the precursor of gelatinase A/72 kDa type IV collagenase/MMP-2 in lung carcinomas correlates with the expression of membrane-type matrix metalloproteinase (MT-MMP) and with lymph node metastasis.
Carcinoma
Anti-invasive effect of MMI-166, a new selective matrix metalloproteinase inhibitor, in cervical carcinoma cell lines.
Carcinoma
Dominative role of MMP-14 over MMP-15 in human urinary bladder carcinoma on the basis of its enhanced specific activity.
Carcinoma
Enhanced production and activation of progelatinase A mediated by membrane-type 1 matrix metalloproteinase in human oral squamous cell carcinomas: implications for lymph node metastasis.
Carcinoma
Enhanced production and activation of progelatinase A mediated by membrane-type 1 matrix metalloproteinase in human papillary thyroid carcinomas.
Carcinoma
Expression and tissue localization of membrane-types 1, 2, and 3 matrix metalloproteinases in human invasive breast carcinomas.
Carcinoma
Expression and tissue localization of membrane-types 1, 2, and 3 matrix metalloproteinases in human urothelial carcinomas.
Carcinoma
Expression of matrix metalloproteinase 2 (MMP-2), membrane-type 1 MMP and tissue inhibitor of metalloproteinase 2 and activation of proMMP-2 in pancreatic duct adenocarcinomas in hamsters treated with N-nitrosobis(2-oxopropyl)amine.
Carcinoma
Expression of membrane-type matrix metalloproteinase in human gastric carcinomas.
Carcinoma
Increased expression of matrix metalloproteinase 7 and 9 and membrane type 1-matrix metalloproteinase in esophageal squamous cell carcinomas.
Carcinoma
Membrane type matrix metalloproteinases (MMPs) show differential expression in non-small cell lung cancer (NSCLC) compared to normal lung: correlation of MMP-14 mRNA expression and proteolytic activity.
Carcinoma
Membrane type-2 matrix metalloproteinases improve the progression of renal cell cancer.
Carcinoma
Membrane-type matrix metalloproteinase (MT-MMP) gene is expressed in stromal cells of human colon, breast, and head and neck carcinomas.
Carcinoma
Membrane-type matrix metalloproteinase expression and matrix metalloproteinase-2 activation in primary human ovarian epithelial carcinoma cells.
Carcinoma
MT2-MMP induces proteolysis and leads to EMT in carcinomas.
Carcinoma
Multiple steps of HLA-G in ovarian carcinoma metastasis: Alter NK cytotoxicity and induce matrix metalloproteinase-15 (MMP-15) expression.
Carcinoma
T cell factor-4 functions as a co-activator to promote NF-?B-dependent MMP-15 expression in lung carcinoma cells.
Carcinoma
The prognostic value of matrix metalloproteinase-7 and matrix metalloproteinase-15 in acute myeloid leukemia.
Carcinoma
[Analysis of differential expression genes related to different metastasis potential of adenoid cystic carcinoma using restriction fragments differential display PCR]
Carcinoma
[Expression of MT1-MMP and RECK protein in human gastric carcinoma].
Carcinoma, Adenoid Cystic
[Analysis of differential expression genes related to different metastasis potential of adenoid cystic carcinoma using restriction fragments differential display PCR]
Carcinoma, Hepatocellular
Analysis of matrix metalloproteinase mRNAs expressed in hepatocellular carcinoma cell lines.
Carcinoma, Hepatocellular
Differential expression and origin of membrane-type 1 and 2 matrix metalloproteinases (MT-MMPs) in association with MMP2 activation in injured human livers.
Carcinoma, Hepatocellular
Expression of matrix metalloproteinases (MMPs) in cultured hepatocellular carcinoma (HCC) cells and surgically resected HCC tissues.
Carcinoma, Hepatocellular
The oncoprotein HBXIP facilitates metastasis of hepatocellular carcinoma cells by activation of MMP15 expression.
Carcinoma, Non-Small-Cell Lung
Regulation of matrix metalloproteinase genes by E2F transcription factors: Rb-Raf-1 interaction as a novel target for metastatic disease.
Carcinoma, Non-Small-Cell Lung
Transcriptional upregulation of MT2-MMP in response to hypoxia is promoted by HIF-1? in cancer cells.
Carcinoma, Ovarian Epithelial
Membrane-type matrix metalloproteinase expression and matrix metalloproteinase-2 activation in primary human ovarian epithelial carcinoma cells.
Carcinoma, Renal Cell
Membrane type-2 matrix metalloproteinases improve the progression of renal cell cancer.
Carcinoma, Squamous Cell
Increased expression of matrix metalloproteinase 7 and 9 and membrane type 1-matrix metalloproteinase in esophageal squamous cell carcinomas.
Carcinoma, Squamous Cell
Membrane type matrix metalloproteinases (MMPs) show differential expression in non-small cell lung cancer (NSCLC) compared to normal lung: correlation of MMP-14 mRNA expression and proteolytic activity.
Cardiomyopathies
Membrane-type-1 matrix metalloproteinase transcription and translation in myocardial fibroblasts from patients with normal left ventricular function and from patients with cardiomyopathy.
Colorectal Neoplasms
Clinicopathological significance of the gene expression of matrix metalloproteinases and reversion-inducing cysteine-rich protein with Kazal motifs in patients with colorectal cancer: MMP-2 gene expression is a useful predictor of liver metastasis from colorectal cancer.
Colorectal Neoplasms
Cyclooxygenase-2 expression correlates with membrane-type-1 matrix metalloproteinase expression in colorectal cancer tissue.
Colorectal Neoplasms
Expression and localization of membrane-type-1 matrix metalloproteinase, CD 44, and laminin-5gamma2 chain during colorectal carcinoma tumor progression.
Colorectal Neoplasms
Immunohistochemical detection of membrane-type-1-matrix metalloproteinase in colorectal carcinoma.
Colorectal Neoplasms
Matrix metalloproteinases 15 and 19 are stromal regulators of colorectal cancer development from the early stages.
Colorectal Neoplasms
Profiling markers of prognosis in colorectal cancer.
Corneal Dystrophies, Hereditary
Downregulation of IL-7 and IL-7R Reduces Membrane-Type Matrix Metalloproteinase 14 in Granular Corneal Dystrophy Type 2 Keratocyte.
Cysts
E-cadherin cleavage by MT2-MMP regulates apical junctional signaling and epithelial homeostasis in the intestine.
Diabetes, Gestational
Fetal Insulin and IGF-II Contribute to Gestational Diabetes Mellitus (GDM)-Associated Up-Regulation of Membrane-Type Matrix Metalloproteinase 1 (MT1-MMP) in the Human Feto-Placental Endothelium.
Dysplastic Nevus Syndrome
Coordinate expression of membrane type-matrix metalloproteinases-2 and 3 (MT2-MMP and MT3-MMP) and matrix metalloproteinase-2 (MMP-2) in primary and metastatic melanoma cells.
Esophageal Neoplasms
Immunochemical staining of MT2-MMP correlates positively to angiogenesis of human esophageal cancer.
Fetal Growth Retardation
Membrane-Type Matrix Metalloproteinase 1 (MT1-MMP) Regulates Trophoblast Functions and Is Reduced in Fetal Growth Restriction.
Fibrosarcoma
Cellular cholesterol regulates MT1 MMP dependent activation of MMP 2 via MEK-1 in HT1080 fibrosarcoma cells.
Fibrosarcoma
Investigation of the role of Endo180/urokinase-type plasminogen activator receptor-associated protein as a collagenase 3 (matrix metalloproteinase 13) receptor.
Fibrosarcoma
Membrane type 1 matrix metalloproteinase and gelatinase A synergistically degrade type 1 collagen in a cell model.
Fibrosarcoma
Proteolytic processing of membrane-type-1 matrix metalloproteinase is associated with gelatinase A activation at the cell surface.
Fibrosarcoma
The role of MT2-MMP in cancer progression.
Genetic Diseases, Inborn
Assignment of human membrane-type matrix metalloproteinase-2 (MT2-MMP) gene to 16q12 by FISH and PCR-based human/rodent cell hybrid mapping panel analysis.
Glioblastoma
Expression and tissue localization of membrane-type 1, 2, and 3 matrix metalloproteinases in human astrocytic tumors.
Glioblastoma
Expression of matrix metalloproteinases and their tissue inhibitors in human brain tumors.
Glioblastoma
Tumor cell-matrix interaction: pericellular matrix degradation and metastasis.
Glioma
Induction of membrane-type-1 matrix metalloproteinase by epidermal growth factor-mediated signaling in gliomas.
Glioma
Matrix metalloproteinases in human gliomas: activation of matrix metalloproteinase-2 (MMP-2) may be correlated with membrane-type-1 matrix metalloproteinase (MT1-MMP) expression.
Glioma
miR-150-5p and miR-133a suppress glioma cell proliferation and migration through targeting membrane-type-1 matrix metalloproteinase.
Glioma
The chemokine stromal cell derived factor-1 (CXCL12) promotes glioma invasiveness through MT2-matrix metalloproteinase.
Glioma
The value and correlation between PRL-3 expression and matrix metalloproteinase activity and expression in human gliomas.
Glioma
Tumor cell-matrix interaction: pericellular matrix degradation and metastasis.
Infections
EMMPRIN (CD 147) is a central activator of extracellular matrix degradation by Chlamydia pneumoniae-infected monocytes. Implications for plaque rupture.
Infections
Mayaro Virus Infects Human Chondrocytes and Induces the Expression of Arthritis-Related Genes Associated with Joint Degradation.
Kidney Neoplasms
Membrane type-2 matrix metalloproteinases improve the progression of renal cell cancer.
Leg Ulcer
Elevated expression of extracellular matrix metalloproteinase inducer (CD147) and membrane-type matrix metalloproteinases in venous leg ulcers.
Leukemia
Sorafenib treatment of FLT3-ITD+ acute myeloid leukemia: favorable initial outcome and mechanisms of subsequent non-responsiveness associated with a D835 mutation.
Leukemia, Myeloid, Acute
The prognostic value of matrix metalloproteinase-7 and matrix metalloproteinase-15 in acute myeloid leukemia.
Liver Cirrhosis
Generation of mmp15b Zebrafish Mutant to Investigate Liver Diseases.
Lung Neoplasms
LPP inhibits collective cell migration during lung cancer dissemination.
Lung Neoplasms
MT2-MMP expression associates with tumor progression and angiogenesis in human lung cancer.
Lung Neoplasms
Regulation of matrix metalloproteinase genes by E2F transcription factors: Rb-Raf-1 interaction as a novel target for metastatic disease.
Lung Neoplasms
T cell factor-4 functions as a co-activator to promote NF-?B-dependent MMP-15 expression in lung carcinoma cells.
Lung Neoplasms
Transcriptional upregulation of MT2-MMP in response to hypoxia is promoted by HIF-1? in cancer cells.
Lung Neoplasms
[Expression of membrane-type matrix metalloproteinase (MT-MMP) and activation of MMP-2 in lung cancer]
Lymphatic Metastasis
Activation of the precursor of gelatinase A/72 kDa type IV collagenase/MMP-2 in lung carcinomas correlates with the expression of membrane-type matrix metalloproteinase (MT-MMP) and with lymph node metastasis.
Lymphatic Metastasis
Immunochemical staining of MT2-MMP correlates positively to angiogenesis of human esophageal cancer.
Lymphatic Metastasis
MT2-MMP expression associates with tumor progression and angiogenesis in human lung cancer.
Lymphatic Metastasis
Prognostic value of membrane type 1 and 2 matrix metalloproteinase expression and gelatinase A activity in bladder cancer.
Medulloblastoma
Expression of matrix metalloproteinases and their tissue inhibitors in human brain tumors.
Melanoma
Coordinate expression of membrane type-matrix metalloproteinases-2 and 3 (MT2-MMP and MT3-MMP) and matrix metalloproteinase-2 (MMP-2) in primary and metastatic melanoma cells.
Melanoma
Expression of E1AF, an ets-oncogene transcription factor, highly correlates with malignant phenotype of malignant melanoma through up-regulation of the membrane-type-1 matrix metalloproteinase gene.
Melanoma
Membrane-type-3 matrix metalloproteinase (MT3-MMP) functions as a matrix composition-dependent effector of melanoma cell invasion.
Melanoma
Variability in melanoma metalloproteinase expression profiling.
Meningioma
Matrix metalloproteinases in human gliomas: activation of matrix metalloproteinase-2 (MMP-2) may be correlated with membrane-type-1 matrix metalloproteinase (MT1-MMP) expression.
Neoplasm Metastasis
Activation of the precursor of gelatinase A/72 kDa type IV collagenase/MMP-2 in lung carcinomas correlates with the expression of membrane-type matrix metalloproteinase (MT-MMP) and with lymph node metastasis.
Neoplasm Metastasis
Analysis of matrix metalloproteinase mRNAs expressed in hepatocellular carcinoma cell lines.
Neoplasm Metastasis
Clinicopathological significance of the gene expression of matrix metalloproteinases and reversion-inducing cysteine-rich protein with Kazal motifs in patients with colorectal cancer: MMP-2 gene expression is a useful predictor of liver metastasis from colorectal cancer.
Neoplasm Metastasis
Differential expression and origin of membrane-type 1 and 2 matrix metalloproteinases (MT-MMPs) in association with MMP2 activation in injured human livers.
Neoplasm Metastasis
Differentiated expression of membrane type metalloproteinases (MMP-14, MMP-15) and pro-MMP2 in laryngeal squamous cell carcinoma. A novel mechanism.
Neoplasm Metastasis
Expression and tissue localization of membrane-types 1, 2, and 3 matrix metalloproteinases in human invasive breast carcinomas.
Neoplasm Metastasis
Expression of membrane-type matrix metalloproteinase 1 (MT1-MMP) in tumor cells enhances pulmonary metastasis in an experimental metastasis assay.
Neoplasm Metastasis
High expression of integrin ?6 in association with the Rho-Rac pathway identifies a poor prognostic subgroup within HER2 amplified breast cancers.
Neoplasm Metastasis
Identification of MMP-15 as an anti-apoptotic factor in cancer cells.
Neoplasm Metastasis
Immunochemical staining of MT2-MMP correlates positively to angiogenesis of human esophageal cancer.
Neoplasm Metastasis
Immunohistochemical detection of membrane-type-1-matrix metalloproteinase in colorectal carcinoma.
Neoplasm Metastasis
Increased MT2-MMP expression in gastric cancer patients is associated with poor prognosis.
Neoplasm Metastasis
Membrane-type-1 matrix metalloproteinase confers tumorigenicity on nonmalignant epithelial cells.
Neoplasm Metastasis
MMP-14 can serve as a prognostic marker in patients with supraglottic cancer.
Neoplasm Metastasis
MT2-MMP expression associates with tumor progression and angiogenesis in human lung cancer.
Neoplasm Metastasis
Multiple steps of HLA-G in ovarian carcinoma metastasis: Alter NK cytotoxicity and induce matrix metalloproteinase-15 (MMP-15) expression.
Neoplasm Metastasis
Progesterone and calcitriol reduce invasive potential of endometrial cancer cells by targeting ARF6, NEDD9 and MT1-MMP.
Neoplasm Metastasis
Prognostic value of membrane type 1 and 2 matrix metalloproteinase expression and gelatinase A activity in bladder cancer.
Neoplasm Metastasis
The oncoprotein HBXIP facilitates metastasis of hepatocellular carcinoma cells by activation of MMP15 expression.
Neoplasm Metastasis
Upregulation of LINC00659 expression predicts a poor prognosis and promotes migration and invasion of gastric cancer cells.
Neoplasm Metastasis
[Analysis of differential expression genes related to different metastasis potential of adenoid cystic carcinoma using restriction fragments differential display PCR]
Neoplasms
A Mathematical Framework for Modelling the Metastatic Spread of Cancer.
Neoplasms
A study on angiogenesis-related matrix metalloproteinase networks in primary hepatocellular carcinoma.
Neoplasms
Analysis of 16 different matrix metalloproteinases (MMP-1 to MMP-20) in the synovial membrane: different profiles in trauma and rheumatoid arthritis.
Neoplasms
Comprehensive analysis of matrix metalloproteinase and tissue inhibitor expression in pancreatic cancer: increased expression of matrix metalloproteinase-7 predicts poor survival.
Neoplasms
Correlation of tumor- and stromal-derived MT1-MMP expression with progression of human ovarian tumors in SCID mice.
Neoplasms
Cyclooxygenase-2 expression correlates with membrane-type-1 matrix metalloproteinase expression in colorectal cancer tissue.
Neoplasms
Differential expression and origin of membrane-type 1 and 2 matrix metalloproteinases (MT-MMPs) in association with MMP2 activation in injured human livers.
Neoplasms
Differentiated expression of membrane type metalloproteinases (MMP-14, MMP-15) and pro-MMP2 in laryngeal squamous cell carcinoma. A novel mechanism.
Neoplasms
Dominative role of MMP-14 over MMP-15 in human urinary bladder carcinoma on the basis of its enhanced specific activity.
Neoplasms
Effects of bevacizumab in mouse model of endometrial cancer: Defining the molecular basis for resistance.
Neoplasms
Expression and localization of membrane-type-1 matrix metalloproteinase, CD 44, and laminin-5gamma2 chain during colorectal carcinoma tumor progression.
Neoplasms
Expression and tissue localization of membrane-type 1, 2, and 3 matrix metalloproteinases in human astrocytic tumors.
Neoplasms
Expression and tissue localization of membrane-types 1, 2, and 3 matrix metalloproteinases in human invasive breast carcinomas.
Neoplasms
Expression and tissue localization of membrane-types 1, 2, and 3 matrix metalloproteinases in human urothelial carcinomas.
Neoplasms
Expression of matrix metalloproteinase 2 (MMP-2), membrane-type 1 MMP and tissue inhibitor of metalloproteinase 2 and activation of proMMP-2 in pancreatic duct adenocarcinomas in hamsters treated with N-nitrosobis(2-oxopropyl)amine.
Neoplasms
Expression of matrix metalloproteinases and their inhibitors in medulloblastomas and their prognostic relevance.
Neoplasms
Expression of membrane-type 1, 2, and 3 matrix metalloproteinases messenger RNA in ovarian carcinoma cells in serous effusions.
Neoplasms
Expression of membrane-type matrix metalloproteinase 1 (MT1-MMP) in tumor cells enhances pulmonary metastasis in an experimental metastasis assay.
Neoplasms
Expression of MMPs and TIMPs genes in human breast cancer epithelial cells depends on cell culture conditions and is associated with their invasive potential.
Neoplasms
Expression pattern of four membrane-type matrix metalloproteinases in the normal and diseased mouse mammary gland.
Neoplasms
High expression of integrin ?6 in association with the Rho-Rac pathway identifies a poor prognostic subgroup within HER2 amplified breast cancers.
Neoplasms
Identification of MMP-15 as an anti-apoptotic factor in cancer cells.
Neoplasms
Immunochemical staining of MT2-MMP correlates positively to angiogenesis of human esophageal cancer.
Neoplasms
Increased MT2-MMP expression in gastric cancer patients is associated with poor prognosis.
Neoplasms
Induction of a MT1-MMP and MT2-MMP-dependent basement membrane transmigration program in cancer cells by Snail1.
Neoplasms
Induction of membrane-type matrix metalloproteinase 1 (MT1-MMP) expression in human fibroblasts by breast adenocarcinoma cells.
Neoplasms
Insulin Receptor Substrate 2 plays Important Roles in 17betaEstradiol Induced Bone Formation.
Neoplasms
LPP inhibits collective cell migration during lung cancer dissemination.
Neoplasms
Matrix metalloproteinase 15 plays a pivotal role in human first trimester cytotrophoblast invasion and is not altered by maternal obesity.
Neoplasms
Matrix metalloproteinases 15 and 19 are stromal regulators of colorectal cancer development from the early stages.
Neoplasms
Membrane type-2 matrix metalloproteinases improve the progression of renal cell cancer.
Neoplasms
Membrane-type-1 matrix metalloproteinase confers tumorigenicity on nonmalignant epithelial cells.
Neoplasms
Membrane-type-3 matrix metalloproteinase (MT3-MMP) functions as a matrix composition-dependent effector of melanoma cell invasion.
Neoplasms
Microarray analysis of gene expression in chondrosarcoma cells treated with bee venom.
Neoplasms
MMP-7 and SGCE as distinctive molecular factors in sporadic colorectal cancers from the mutator phenotype pathway.
Neoplasms
MMP16 Mediates a Proteolytic Switch to Promote Cell-Cell Adhesion, Collagen Alignment, and Lymphatic Invasion in Melanoma.
Neoplasms
MT1-MMP regulates VEGF-A expression through a complex with VEGFR-2 and Src.
Neoplasms
MT2-MMP expression associates with tumor progression and angiogenesis in human lung cancer.
Neoplasms
Multiple steps of HLA-G in ovarian carcinoma metastasis: Alter NK cytotoxicity and induce matrix metalloproteinase-15 (MMP-15) expression.
Neoplasms
Progesterone and calcitriol reduce invasive potential of endometrial cancer cells by targeting ARF6, NEDD9 and MT1-MMP.
Neoplasms
Prognostic value of membrane type 1 and 2 matrix metalloproteinase expression and gelatinase A activity in bladder cancer.
Neoplasms
RNA interference targeting CML66, a novel tumor antigen, inhibits proliferation, invasion and metastasis of HeLa cells.
Neoplasms
Role of MT-MMPs and MMP-2 in pancreatic cancer progression.
Neoplasms
Role of tissue inhibitor of metalloproteinases-2 (TIMP-2) in regulation of pro-gelatinase A activation catalyzed by membrane-type matrix metalloproteinase-1 (MT1-MMP) in human cancer cells.
Neoplasms
T cell factor-4 functions as a co-activator to promote NF-?B-dependent MMP-15 expression in lung carcinoma cells.
Neoplasms
Targeting the warburg effect, which arises in tumor cells expressing membrane-type-1 matrix metalloproteinase.
Neoplasms
The chemokine stromal cell derived factor-1 (CXCL12) promotes glioma invasiveness through MT2-matrix metalloproteinase.
Neoplasms
The prognostic value of matrix metalloproteinase-7 and matrix metalloproteinase-15 in acute myeloid leukemia.
Neoplasms
The role of MT2-MMP in cancer progression.
Neoplasms
Transcriptional upregulation of MT2-MMP in response to hypoxia is promoted by HIF-1? in cancer cells.
Neoplasms
Tumor cell invasion of collagen matrices requires coordinate lipid agonist-induced G-protein and membrane-type matrix metalloproteinase-1-dependent signaling.
Neoplasms
Upregulation of LINC00659 expression predicts a poor prognosis and promotes migration and invasion of gastric cancer cells.
Neoplasms
Whole genome expression profiling and screening for differentially expressed cytokine genes in human bone marrow endothelial cells treated with humoral inhibitors in liver cirrhosis.
Nephritis
Macrophage-derived MT1-MMP and increased MMP-2 activity are associated with glomerular damage in crescentic glomerulonephritis.
Nevus
Coordinate expression of membrane type-matrix metalloproteinases-2 and 3 (MT2-MMP and MT3-MMP) and matrix metalloproteinase-2 (MMP-2) in primary and metastatic melanoma cells.
Obesity
Obesity-associated Dysregulation of Calpastatin and MMP-15 in Adipose-derived Stromal Cells Results in their Enhanced Invasion R1.
Obesity, Maternal
Matrix metalloproteinase 15 plays a pivotal role in human first trimester cytotrophoblast invasion and is not altered by maternal obesity.
Osteoarthritis
Expression of membrane-type matrix metalloproteinases in synovial tissue from patients with rheumatoid arthritis or osteoarthritis.
Ovarian Neoplasms
Expression of various matrix proteases and Ets family transcriptional factors in ovarian cancer cell lines: correlation to invasive potential.
Ovarian Neoplasms
MT2-MMP induces proteolysis and leads to EMT in carcinomas.
Ovarian Neoplasms
Multiple steps of HLA-G in ovarian carcinoma metastasis: Alter NK cytotoxicity and induce matrix metalloproteinase-15 (MMP-15) expression.
Pancreatic Neoplasms
Overexpression of membrane-type 2 matrix metalloproteinase induced by hypoxia-inducible factor-1? in pancreatic cancer: Implications for tumor progression and prognosis.
Pancreatic Neoplasms
Role of MT-MMPs and MMP-2 in pancreatic cancer progression.
Pancreatic Neoplasms
Transcriptional upregulation of MT2-MMP in response to hypoxia is promoted by HIF-1? in cancer cells.
Pancreatitis, Chronic
Role of MT-MMPs and MMP-2 in pancreatic cancer progression.
Pre-Eclampsia
Gene expression analysis of MMPs in women with preeclampsia using cell-free fetal RNA in maternal plasma.
Pre-Eclampsia
MMP-15 is upregulated in preeclampsia, but does not cleave endoglin to produce soluble endoglin.
Prostatic Neoplasms
Identification of degradome components associated with prostate cancer progression by expression analysis of human prostatic tissues.
Prostatic Neoplasms
Membrane-type-1 matrix metalloproteinase, matrix metalloproteinase 2, and tissue inhibitor of matrix proteinase 2 in prostate cancer: identification of patients with poor prognosis by immunohistochemistry.
Sarcoma
MMP14 in Sarcoma: A Regulator of Tumor Microenvironment Communication in Connective Tissues.
Stomach Neoplasms
Increased MT2-MMP expression in gastric cancer patients is associated with poor prognosis.
Stomach Neoplasms
Matrix metalloproteinase gene expressions might be oxidative stress targets in gastric cancer cell lines.
Stomach Neoplasms
Silencing of the MMP-3 gene by siRNA transfection in gastric cancer AGS cells.
Stomach Neoplasms
The role of MT2-MMP in cancer progression.
Stomach Neoplasms
UBE2C Is a Potential Biomarker of Intestinal-Type Gastric Cancer With Chromosomal Instability.
Synovitis
Analysis of 16 different matrix metalloproteinases (MMP-1 to MMP-20) in the synovial membrane: different profiles in trauma and rheumatoid arthritis.
Urinary Bladder Neoplasms
Dominative role of MMP-14 over MMP-15 in human urinary bladder carcinoma on the basis of its enhanced specific activity.
Urinary Bladder Neoplasms
Silencing LINC00482 inhibits tumor-associated inflammation and angiogenesis through down-regulation of MMP-15 via FOXA1 in bladder cancer.
Uterine Cervical Neoplasms
Silencing PROK2 Inhibits Invasion of Human Cervical Cancer Cells by Targeting MMP15 Expression.
Uterine Cervical Neoplasms
Transcriptional upregulation of MT2-MMP in response to hypoxia is promoted by HIF-1? in cancer cells.
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Boeckmann, B.; Bairoch, A.; Apweiler, R.; Blatter, M.C.; Estreicher, A.; Gasteiger, E.; Martin M.J.; Michoud, K.; O'Donovan, C.; Phan, I.; Pilbout, S.; Schneider, M.
The SWISS-PROT protein knowledgebase and its supplement TrEMBL
Nucleic Acids Res.
31
365-370
2003
Homo sapiens (P51511), Mus musculus (O54732)
brenda
Butler, G.S.; Will, H.; Atkinson, S.J.; Murphy, G.
Membrane-type-2 matrix metalloproteinase can initiate the processing of progelatinase A and is regulated by the tissue inhibitors of metalloproteinases
Eur. J. Biochem.
244
653-657
1997
Homo sapiens
brenda
Shofuda, K.I.; Moriyama, K.; Nishihashi, A.; Higashi, S.; Mizushima, H.; Yasumitsu, H.; Miki, K.; Sato, H.; Seiki, M.; Miyazaki, K.
Role of tissue inhibitor of metalloproteinases-2 (TIMP-2) in regulation of pro-gelatinase A activation catalyzed by membrane-type matrix metalloproteinase-1 (MT1-MMP) in human cancer cells
J. Biochem.
124
462-470
1998
Homo sapiens
brenda
Belkin, A.M.; Akimov, S.S.; Zaritskaya, L.S.; Ratnikov, B.I.; Deryugina, E.I.; Strongin, A.Y.
Matrix-dependent proteolysis of surface transglutaminase by membrane-type metalloproteinase regulates cancer cell adhesion and locomotion
J. Biol. Chem.
276
18415-18422
2001
Homo sapiens (P50281)
brenda
Wallard, M.J.; Pennington, C.J.; Veerakumarasivam, A.; Burtt, G.; Mills, I.G.; Warren, A.; Leung, H.Y.; Murphy, G.; Edwards, D.R.; Neal, D.E.; Kelly, J.D.
Comprehensive profiling and localisation of the matrix metalloproteinases in urothelial carcinoma
Br. J. Cancer
94
569-577
2006
Homo sapiens
brenda
Jones, L.E.; Humphreys, M.J.; Campbell, F.; Neoptolemos, J.P.; Boyd, M.T.
Comprehensive analysis of matrix metalloproteinase and tissue inhibitor expression in pancreatic cancer: increased expression of matrix metalloproteinase-7 predicts poor survival
Clin. Cancer Res.
10
2832-2845
2004
Homo sapiens
brenda
Abraham, R.; Schaefer, J.; Rothe, M.; Bange, J.; Knyazev, P.; Ullrich, A.
Identification of MMP-15 as an anti-apoptotic factor in cancer cells
J. Biol. Chem.
280
34123-34132
2005
Homo sapiens (P51511), Homo sapiens
brenda
Hiden, U.; Wadsack, C.; Prutsch, N.; Gauster, M.; Weiss, U.; Frank, H.G.; Schmitz, U.; Fast-Hirsch, C.; Hengstschlaeger, M.; Poetgens, A.; Rueben, A.; Knoefler, M.; Haslinger, P.; Huppertz, B.; Bilban, M.; Kaufmann, P.; Desoye, G.
The first trimester human trophoblast cell line ACH-3P: a novel tool to study autocrine/paracrine regulatory loops of human trophoblast subpopulations - TNF-alpha stimulates MMP15 expression
BMC Dev. Biol.
7
137
2007
Homo sapiens
brenda
Morrison, C.J.; Overall, C.M.
TIMP independence of matrix metalloproteinase (MMP)-2 activation by membrane type 2 (MT2)-MMP is determined by contributions of both the MT2-MMP catalytic and hemopexin C domains
J. Biol. Chem.
281
26528-26539
2006
Homo sapiens
brenda
Kaituu-Lino, T.J.; Palmer, K.; Tuohey, L.; Ye, L.; Tong, S.
MMP-15 is upregulated in preeclampsia, but does not cleave endoglin to produce soluble endoglin
PLoS ONE
7
e39864
2012
Homo sapiens (P51511)
brenda
Majali-Martinez, A.; Velicky, P.; Pollheimer, J.; Knoefler, M.; Yung, H.W.; Burton, G.J.; Tabrizi-Wizsy, N.G.; Lang, U.; Hiden, U.; Desoye, G.; Dieber-Rotheneder, M.
Endothelin-1 down-regulates matrix metalloproteinase 14 and 15 expression in human first trimester trophoblasts via endothelin receptor type B
Hum. Reprod.
32
46-54
2017
Homo sapiens (P51511), Homo sapiens
brenda
Wu, Y.; Pan, S.; Leng, J.; Xie, T.; Jamal, M.; Yin, Q.; Li, J.; He, C.; Dong, X.; Shao, L.; Zhang, Q.
The prognostic value of matrix metalloproteinase-7 and matrix metalloproteinase-15 in acute myeloid leukemia
J. Cell. Biochem.
120
10613-10624
2019
Homo sapiens (P51511), Homo sapiens
brenda