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Abortion, Spontaneous
Functional single nucleotide polymorphisms of matrix metalloproteinase 7 and 12 genes in idiopathic recurrent spontaneous abortion.
Acidosis
Glycolysis-derived acidic microenvironment as a driver of endothelial dysfunction in systemic sclerosis.
Acrodermatitis
Enhanced expression of human metalloelastase (MMP-12) in cutaneous granulomas and macrophage migration.
Acute Lung Injury
Effect of hirudin on the levels of acute lung injury rat tumor necrosis factor-? and matrix metalloproteinase-12.
Acute Lung Injury
The role of metalloelastase in immune complex-induced acute lung injury.
Adenocarcinoma
Increased expression of human macrophage metalloelastase (MMP-12) is associated with the invasion of endometrial adenocarcinoma.
Adenocarcinoma
Matrix metalloproteinase 12 overexpression in lung epithelial cells plays a key role in emphysema to lung bronchioalveolar adenocarcinoma transition.
Adenocarcinoma
Serum MMP7, MMP10 and MMP12 level as negative prognostic markers in colon cancer patients.
Adenocarcinoma
Upregulation and differential expression of matrilysin (MMP-7) and metalloelastase (MMP-12) and their inhibitors TIMP-1 and TIMP-3 in Barrett's oesophageal adenocarcinoma.
Adenocarcinoma of Lung
Knockdown of MMP12 inhibits the growth and invasion of lung adenocarcinoma cells.
Adenocarcinoma of Lung
Matrix metalloproteinase 12 overexpression in myeloid lineage cells plays a key role in modulating myelopoiesis, immune suppression, and lung tumorigenesis.
Adenocarcinoma of Lung
Secreted phosphoprotein 1 upstream invasive network construction and analysis of lung adenocarcinoma compared with human normal adjacent tissues by integrative biocomputation.
Albuminuria
Lysyl oxidase like-2 contributes to renal fibrosis in Col4?3/Alport mice.
Amaurosis Fugax
Differences in matrix metalloproteinase-1 and matrix metalloproteinase-12 transcript levels among carotid atherosclerotic plaques with different histopathological characteristics.
Anetoderma
Enhanced expression of human metalloelastase (MMP-12) in cutaneous granulomas and macrophage migration.
Aneurysm
Cigarette smoking increases aortic dilatation without affecting matrix metalloproteinase-9 and -12 expression in a modified mouse model of aneurysm formation.
Aneurysm
Development of selective inhibitors and substrate of matrix metalloproteinase-12.
Aneurysm
Diabetes Reduces Severity of Aortic Aneurysms Depending on the Presence of Cell Division Autoantigen 1 (CDA1).
Aneurysm
Effect of matrix metalloproteinase inhibition on progression of atherosclerosis and aneurysm in LDL receptor-deficient mice overexpressing MMP-3, MMP-12, and MMP-13 and on restenosis in rats after balloon injury.
Aneurysm
Expression gradient of metalloproteinases and their inhibitors from proximal to distal segments of abdominal aortic aneurysm.
Aneurysm
Genes predisposing to rapid aneurysm growth.
Aneurysm
Loss of matrix metalloproteinase-9 or matrix metalloproteinase-12 protects apolipoprotein E-deficient mice against atherosclerotic media destruction but differentially affects plaque growth.
Aneurysm
Macrophage metalloelastase accelerates the progression of atherosclerosis in transgenic rabbits.
Aneurysm
Matrix metalloproteinase haplotypes associated with coronary artery aneurysm formation in patients with Kawasaki disease.
Aneurysm
Matrix metalloproteinase-12 (MMP-12) in osteoclasts: new lesson on the involvement of MMPs in bone resorption.
Aneurysm
MMP-12 has a role in abdominal aortic aneurysms in mice.
Aneurysm
Multiple sites of vascular dilation or aneurysmal disease and matrix metalloproteinase genetic variants in patients with abdominal aortic aneurysm.
Aneurysm
NMR and bioinformatics discovery of exosites that tune metalloelastase specificity for solubilized elastin and collagen triple helices.
Aneurysm
Optical imaging of MMP-12 active form in inflammation and aneurysm.
Aneurysm
Systemic Administration of Ribbon-type Decoy Oligodeoxynucleotide Against Nuclear Factor ?B and Ets Prevents Abdominal Aortic Aneurysm in Rat Model.
Aneurysm
TGF-beta activity protects against inflammatory aortic aneurysm progression and complications in angiotensin II-infused mice.
Aneurysm, Dissecting
Expression of matrix metalloproteinase-12 in aortic dissection.
Aneurysm, Dissecting
MMP-12 and macrophage activation in acute aortic dissection.
Aneurysm, Dissecting
MMP-12 as a new marker of Stanford-A acute aortic dissection.
Angina, Stable
Expression of matrix metalloproteinases-12 in ST-segment elevation myocardial infarction: A case-control study.
Anti-Glomerular Basement Membrane Disease
Matrix metalloproteinase-12 (MMP-12) deficiency attenuates experimental crescentic anti-GBM glomerulonephritis.
Aortic Aneurysm
Interleukin-3 is required for thoracic aneurysm and dissection in a mouse model.
Aortic Aneurysm
Solution structure of inhibitor-free human metalloelastase (MMP-12) indicates an internal conformational adjustment.
Aortic Aneurysm, Abdominal
Expression and localization of macrophage elastase (matrix metalloproteinase-12) in abdominal aortic aneurysms.
Aortic Aneurysm, Abdominal
Expression of matrix metalloproteinase-12 in aortic dissection.
Aortic Aneurysm, Abdominal
Genes predisposing to rapid aneurysm growth.
Aortic Aneurysm, Abdominal
Genotype-phenotype relationships in an investigation of the role of proteases in abdominal aortic aneurysm expansion.
Aortic Aneurysm, Abdominal
Hydroxamate-Based Selective Macrophage Elastase (MMP-12) Inhibitors and Radiotracers for Molecular Imaging.
Aortic Aneurysm, Abdominal
Influence of matrix metalloproteinase genotype on cardiovascular disease susceptibility and outcome.
Aortic Aneurysm, Abdominal
Matrix metalloproteinase 12 modulates high-fat-diet induced glomerular fibrogenesis and inflammation in a mouse model of obesity.
Aortic Aneurysm, Abdominal
MMP-12 has a role in abdominal aortic aneurysms in mice.
Aortic Aneurysm, Abdominal
Novel Matrix Metalloproteinase 12 Selective Radiotracers for Vascular Molecular Imaging.
Aortic Aneurysm, Thoracic
Temporal disparity in the induction of matrix metalloproteinases and tissue inhibitors of metalloproteinases after thoracic aortic aneurysm formation.
Aortic Diseases
Upregulation of elastase proteins results in aortic dilatation in mucopolysaccharidosis I mice.
Appendicitis
Biomarkers to estimate the probability of complicated appendicitis.
Arteriosclerosis
Reduced intragraft mRNA expression of matrix metalloproteinases Mmp3, Mmp12, Mmp13 and Adam8, and diminished transplant arteriosclerosis in Ccr5-deficient mice.
Arteritis
MMP-12, a novel matrix metalloproteinase associated with giant cell arteritis.
Arthritis
In vivo imaging of matrix metalloproteinase 12 and matrix metalloproteinase 13 activities in the mouse model of collagen-induced arthritis.
Arthritis
Macrophage matrix metalloproteinase-12 dampens inflammation and neutrophil influx in arthritis.
Arthritis
Overexpression of human matrix metalloproteinase-12 enhances the development of inflammatory arthritis in transgenic rabbits.
Arthritis, Experimental
In vivo imaging of matrix metalloproteinase 12 and matrix metalloproteinase 13 activities in the mouse model of collagen-induced arthritis.
Arthritis, Psoriatic
Differences in Osteoimmunological Biomarkers Predictive of Psoriatic Arthritis among a Large Italian Cohort of Psoriatic Patients.
Arthritis, Rheumatoid
Association of increased expression of macrophage elastase (matrix metalloproteinase 12) with rheumatoid arthritis.
Arthritis, Rheumatoid
Design, synthesis, biological evaluation, and NMR studies of a new series of arylsulfones as selective and potent matrix metalloproteinase-12 inhibitors.
Arthritis, Rheumatoid
Distinct gene expression of osteopontin in patients with ulcerative colitis.
Arthritis, Rheumatoid
Fractionation of elastase-type enzyme activity in biological fluids using a centrifugal analyser.
Arthritis, Rheumatoid
Overexpression of human matrix metalloproteinase-12 enhances the development of inflammatory arthritis in transgenic rabbits.
Arthritis, Rheumatoid
Selective MMP-12 inhibitors: WO-2008057254.
Arthritis, Rheumatoid
Solution structure of inhibitor-free human metalloelastase (MMP-12) indicates an internal conformational adjustment.
Arthritis, Rheumatoid
Variation in the matrix metalloproteinase-3, -7, -12 and -13 genes is associated with functional status in rheumatoid arthritis.
Asthma
Association study of matrix metalloproteinase-12 gene polymorphisms and asthma in a Japanese population.
Asthma
Defining the molecular role of gp91phox in the immune manifestation of acute allergic asthma using a preclinical murine model.
Asthma
Discovery of potent and selective matrix metalloprotease 12 inhibitors for the potential treatment of chronic obstructive pulmonary disease (COPD).
Asthma
Increase in the expression of matrix metalloproteinase-12 in the airways of rats with allergic bronchial asthma.
Asthma
Increased MMP12 mRNA expression in induced sputum was correlated with airway eosinophilic inflammation in asthma patients: Evidence from bioinformatic analysis and experiment verification.
Asthma
Induction and regulation of matrix metalloproteinase-12 in human airway smooth muscle cells.
Asthma
Matrix metalloproteinase 12 silencing: A therapeutic approach to treat pathological lung tissue remodeling?
Asthma
Matrix metalloproteinase 12, asthma, and COPD.
Asthma
Matrix metalloproteinase-12 is a therapeutic target for asthma in children and young adults.
Asthma
Matrix metalloproteinases in the pathogenesis of asthma and COPD: implications for therapy.
Asthma
MMP-12, a Promising Therapeutic Target for Neurological Diseases.
Asthma
MMP12 -82 A>G Promoter Polymorphism in Bronchial Asthma in a Population of Central Bulgaria.
Asthma
MMP12, lung function, and COPD in high-risk populations.
Asthma
Multidimensional endotyping in patients with severe asthma reveals inflammatory heterogeneity in matrix metalloproteinases and chitinase 3-like protein 1.
Asthma
New asthma biomarkers: lessons from murine models of acute and chronic asthma.
Asthma
Revisiting matrix metalloproteinase 12: its role in pathophysiology of asthma and related pulmonary diseases.
Asthma
Role of metalloelastase in a model of allergic lung responses induced by cockroach allergen.
Asthma
Role of T cells in a gp91phox knockout murine model of acute allergic asthma.
Asthma
Selective MMP-12 inhibitors: WO-2008057254.
Asthma
Sputum matrix metalloproteinase-12 in patients with chronic obstructive pulmonary disease and asthma: Relationship to disease severity.
Asthma
[MicroRNAs - new biomarkers of respiratory tract diseases].
Astrocytoma
Expression of matrix metalloproteinases and their inhibitors in human brain tumors.
Atherosclerosis
A MMP derived versican neo-epitope is elevated in plasma from patients with atherosclerotic heart disease.
Atherosclerosis
A selective matrix metalloproteinase-12 inhibitor retards atherosclerotic plaque development in apolipoprotein E-knockout mice.
Atherosclerosis
Activation of Aryl Hydrocarbon Receptor Induces Vascular Inflammation and Promotes Atherosclerosis in Apolipoprotein E-/- Mice.
Atherosclerosis
Activation of inflammatory mediators and potential role of ah-receptor ligands in foam cell formation.
Atherosclerosis
An integrated structure- and pharmacophore-based MMP-12 virtual screening.
Atherosclerosis
Association of SDF1 and MMP12 with Atherosclerosis and Inflammation: Clinical and Experimental Study.
Atherosclerosis
Candidate SNP Markers of Atherogenesis Significantly Shifting the Affinity of TATA-Binding Protein for Human Gene Promoters show stabilizing Natural Selection as a Sum of Neutral Drift Accelerating Atherogenesis and Directional Natural Selection Slowing It.
Atherosclerosis
Cardiovascular protection in females linked to estrogen-dependent inhibition of arterial stiffening and macrophage MMP12.
Atherosclerosis
Carotid atherosclerotic plaque matrix metalloproteinase-12-positive macrophage subpopulation predicts adverse outcome after endarterectomy.
Atherosclerosis
Correlations of MMP-1, MMP-3, and MMP-12 with the degree of atherosclerosis, plaque stability and cardiovascular and cerebrovascular events.
Atherosclerosis
Design, (Radio)Synthesis, and in Vitro and in Vivo Evaluation of Highly Selective and Potent Matrix Metalloproteinase 12 (MMP-12) Inhibitors as Radiotracers for Positron Emission Tomography.
Atherosclerosis
Design, synthesis, biological evaluation, and NMR studies of a new series of arylsulfones as selective and potent matrix metalloproteinase-12 inhibitors.
Atherosclerosis
Development of selective inhibitors and substrate of matrix metalloproteinase-12.
Atherosclerosis
Effect of matrix metalloproteinase inhibition on progression of atherosclerosis and aneurysm in LDL receptor-deficient mice overexpressing MMP-3, MMP-12, and MMP-13 and on restenosis in rats after balloon injury.
Atherosclerosis
Elevated Plasma Levels of MMP-12 Are Associated With Atherosclerotic Burden and Symptomatic Cardiovascular Disease in Subjects With Type 2 Diabetes.
Atherosclerosis
Expression of matrix metalloproteinase-12 in aortic dissection.
Atherosclerosis
Human macrophage metalloelastase (MMP-12) expression is induced in chondrocytes during fetal development and malignant transformation.
Atherosclerosis
Induction and regulation of matrix metalloproteinase-12 by cytokines and CD40 signaling in monocyte/macrophages.
Atherosclerosis
Influence of matrix metalloproteinase-12 on fibrinogen level.
Atherosclerosis
Integrative studies implicate matrix metalloproteinase-12 as a culprit gene for large-artery atherosclerotic stroke.
Atherosclerosis
Loss of matrix metalloproteinase-9 or matrix metalloproteinase-12 protects apolipoprotein E-deficient mice against atherosclerotic media destruction but differentially affects plaque growth.
Atherosclerosis
Macrophage metalloelastase accelerates the progression of atherosclerosis in transgenic rabbits.
Atherosclerosis
Macrophage-specific overexpression of human matrix metalloproteinase-12 in transgenic rabbits.
Atherosclerosis
Matrix metalloproteinase 12 accelerates the initiation of atherosclerosis and stimulates the progression of fatty streaks to fibrous plaques in transgenic rabbits.
Atherosclerosis
Matrix metalloproteinase 12 modulates high-fat-diet induced glomerular fibrogenesis and inflammation in a mouse model of obesity.
Atherosclerosis
Matrix metalloproteinase-12 gene regulation by a PPAR alpha agonist in human monocyte-derived macrophages.
Atherosclerosis
MMP-12-Induced Pro-osteogenic Responses in Human Aortic Valve Interstitial Cells.
Atherosclerosis
Novel Drug Targets for Ischemic Stroke Identified Through Mendelian Randomization Analysis of the Blood Proteome.
Atherosclerosis
Novel transgenic rabbit model sheds light on the puzzling role of matrix metalloproteinase-12 in atherosclerosis.
Atherosclerosis
Selective MMP-12 inhibitors: WO-2008057254.
Atherosclerosis
Solution structure of inhibitor-free human metalloelastase (MMP-12) indicates an internal conformational adjustment.
Atherosclerosis
Transforming growth factor-beta 1 inhibits cytokine-mediated induction of human metalloelastase in macrophages.
Autoimmune Diseases
Candidate SNP Markers of Atherogenesis Significantly Shifting the Affinity of TATA-Binding Protein for Human Gene Promoters show stabilizing Natural Selection as a Sum of Neutral Drift Accelerating Atherogenesis and Directional Natural Selection Slowing It.
Bone Cysts
Macrophage-specific metalloelastase (MMP-12) immunoexpression in the osteochondral unit in osteoarthritis correlates with BMI and disease severity.
Bone Resorption
Matrix metalloproteinase-12 (MMP-12) in osteoclasts: new lesson on the involvement of MMPs in bone resorption.
Bone Resorption
The expression of macrophage and neutrophil elastases in rat periradicular lesions.
Bowen's Disease
Expression of human macrophage metalloelastase (MMP-12) by tumor cells in skin cancer.
Brain Injuries
Expression of MMP-12 after neonatal hypoxic-ischemic brain injury in mice.
Brain Ischemia
Matrix Metalloproteinase-12 Induces Blood-Brain Barrier Damage After Focal Cerebral Ischemia.
Brain Ischemia
Post-transcriptional inactivation of matrix metalloproteinase-12 after focal cerebral ischemia attenuates brain damage.
Breast Neoplasms
Additional MDA-MB-231 breast cancer cell matrix metalloproteinases promote invasiveness.
Breast Neoplasms
Anti-IL-20 monoclonal antibody suppresses breast cancer progression and bone osteolysis in murine models.
Breast Neoplasms
Genetic polymorphisms in the matrix metalloproteinase 12 gene (MMP12) and breast cancer risk and survival: the Shanghai Breast Cancer Study.
Breast Neoplasms
Matrix metalloproteinase single-nucleotide polymorphisms and haplotypes predict breast cancer progression.
Breast Neoplasms
New signaling pathways from cancer progression modulators to mRNA expression of matrix metalloproteinases in breast cancer cells.
Breast Neoplasms
Systemic sclerosis-endothelial cell antiangiogenic pentraxin 3 and matrix metalloprotease 12 control human breast cancer tumor vascularization and development in mice.
Bronchitis
THE ROLE OF POLYMORPHISMS OF MATRIX METALLOPROTEINASES' POLYMORPHISMS 1 AND 12 IN THE FORMATION OF WHEEZING SYNDROME AMONG CHILDREN WITH RECURRENT BRONCHITIS.
Bronchitis, Chronic
Extracellular matrix remodeling genes polymorphisms and risk of chronic bronchitis and recurrent pneumonia in children.
Bronchitis, Chronic
Series "matrix metalloproteinases in lung health and disease": Matrix metalloproteinases in COPD.
Bronchitis, Chronic
[Analysis of polymorphisms of genes associated with immune response and tissue remodeling in occupational chronic bronchitis].
Carcinogenesis
Human Macrophage Metalloelastase Correlates with Angiogenesis and Prognosis of Gastric Carcinoma.
Carcinogenesis
Identification of four genes and biological characteristics of esophageal squamous cell carcinoma by integrated bioinformatics analysis.
Carcinogenesis
Matrix metalloproteinase 12 overexpression in myeloid lineage cells plays a key role in modulating myelopoiesis, immune suppression, and lung tumorigenesis.
Carcinogenesis
Matrix metalloproteinase 12 promotes tumor propagation in the lung.
Carcinoma
A review of molecular pathological markers in vulvar carcinoma: lack of application in clinical practice.
Carcinoma
Analysis of host- and tumor-derived proteinases using a custom dual species microarray reveals a protective role for stromal matrix metalloproteinase-12 in non-small cell lung cancer.
Carcinoma
Clinicopathological significance of human macrophage metalloelastase expression in esophageal squamous cell carcinoma.
Carcinoma
Estimation of salivary matrix metalloproteinases- 12 (MMP- 12) levels among patients presenting with oral submucous fibrosis and oral squamous cell carcinoma.
Carcinoma
Expression of human macrophage metalloelastase (MMP-12) by tumor cells in skin cancer.
Carcinoma
Expression of matrix metalloproteinase-12 is correlated with extracapsular spread of tumor from nodes with metastasis in head and neck squamous cell carcinoma.
Carcinoma
Human Macrophage Metalloelastase Correlates with Angiogenesis and Prognosis of Gastric Carcinoma.
Carcinoma
Macrophage elastase (matrix metalloproteinase-12) suppresses growth of lung metastases.
Carcinoma
Macrophage-derived metalloelastase is responsible for the generation of angiostatin in Lewis lung carcinoma.
Carcinoma
Matrix metalloproteinase 12 promotes tumor propagation in the lung.
Carcinoma
Metalloelastase (MMP-12) expression by tumour cells in squamous cell carcinoma of the vulva correlates with invasiveness, while that by macrophages predicts better outcome.
Carcinoma
mRNA expression of matrix metalloproteases and their inhibitors differs in subtypes of renal cell carcinomas.
Carcinoma
Pathophysiological changes induced by Pseudomonas aeruginosa infection are involved in MMP-12 and MMP-13 upregulation in human carcinoma epithelial cells and a pneumonia mouse model.
Carcinoma
The association between MMP-12 82 A/G polymorphism and susceptibility to various malignant tumors: a meta-analysis.
Carcinoma
The functional polymorphisms on promoter region of matrix metalloproteinase-12, -13 genes may alter the risk of epithelial ovarian carcinoma in chinese.
Carcinoma
The influence of matrix metalloproteinase-2, -9, and -12 promoter polymorphisms on Iranian patients with oesophageal squamous cell carcinoma.
Carcinoma
The overexpression and predictive significance of MMP-12 in esophageal squamous cell carcinoma.
Carcinoma
Type III Secretion System of Pseudomonas aeruginosa Affects Matrix Metalloproteinase 12 (MMP-12) and MMP-13 Expression via Nuclear Factor ?B Signaling in Human Carcinoma Epithelial Cells and a Pneumonia Mouse Model.
Carcinoma
[Association of functional polymorphisms on MMP-12 and MMP-13 gene promoter region with epithelial ovarian carcinoma.]
Carcinoma
[Study on the expression of matrix metalloproteinase-12 and NM_002426 in squamous laryngeal carcinoma]
Carcinoma, Basal Cell
Expression of human macrophage metalloelastase (MMP-12) by tumor cells in skin cancer.
Carcinoma, Hepatocellular
Expression of human macrophage metalloelastase gene in hepatocellular carcinoma: correlation with angiostatin generation and its clinical significance.
Carcinoma, Hepatocellular
Functional polymorphisms in the promoters of MMP-1, MMP-2, MMP-3, MMP-9, MMP-12 and MMP-13 are not associated with hepatocellular carcinoma risk.
Carcinoma, Hepatocellular
Implications of human macrophage metalloelastase and vascular endothelial growth factor gene expression in angiogenesis of hepatocellular carcinoma.
Carcinoma, Hepatocellular
Matrix metalloproteinase 12 expression is associated with tumor FOXP3+ regulatory T cell infiltration and poor prognosis in hepatocellular carcinoma.
Carcinoma, Hepatocellular
No association of MMP-7, MMP-8, and MMP-21 polymorphisms with the risk of hepatocellular carcinoma in a Chinese population.
Carcinoma, Hepatocellular
Optimizing the Diagnostic Role of Alpha-Fetoprotein and Abdominal Ultrasound by Adding Overexpressed Blood mRNA Matrix Metalloproteinase-12 for Diagnosis of HCV-Related Hepatocellular Carcinoma.
Carcinoma, Hepatocellular
Overexpression of matrix metalloproteinase-12 (MMP-12) correlates with poor prognosis of hepatocellular carcinoma.
Carcinoma, Lewis Lung
Analysis of host- and tumor-derived proteinases using a custom dual species microarray reveals a protective role for stromal matrix metalloproteinase-12 in non-small cell lung cancer.
Carcinoma, Lewis Lung
Macrophage elastase (matrix metalloproteinase-12) suppresses growth of lung metastases.
Carcinoma, Lewis Lung
Macrophage-derived metalloelastase is responsible for the generation of angiostatin in Lewis lung carcinoma.
Carcinoma, Lewis Lung
Matrix metalloproteinase 12 promotes tumor propagation in the lung.
Carcinoma, Non-Small-Cell Lung
Analysis of host- and tumor-derived proteinases using a custom dual species microarray reveals a protective role for stromal matrix metalloproteinase-12 in non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
Macrophage Elastase Induces TRAIL-mediated Tumor Cell Death Through its Carboxyterminal Domain.
Carcinoma, Non-Small-Cell Lung
Matrix metalloproteinase 12 promotes tumor propagation in the lung.
Carcinoma, Non-Small-Cell Lung
Matrix metalloproteinase-12 expression correlates with local recurrence and metastatic disease in non-small cell lung cancer patients.
Carcinoma, Non-Small-Cell Lung
T-box transcription factor brachyury promotes tumor cell invasion and metastasis in non-small cell lung cancer via upregulation of matrix metalloproteinase 12.
Carcinoma, Non-Small-Cell Lung
[Research progress of matrix metalloproteinase 12 in non-small cell lung cancer].
Carcinoma, Ovarian Epithelial
The association between MMP-12 82 A/G polymorphism and susceptibility to various malignant tumors: a meta-analysis.
Carcinoma, Ovarian Epithelial
The functional polymorphisms on promoter region of matrix metalloproteinase-12, -13 genes may alter the risk of epithelial ovarian carcinoma in chinese.
Carcinoma, Ovarian Epithelial
[Association of functional polymorphisms on MMP-12 and MMP-13 gene promoter region with epithelial ovarian carcinoma.]
Carcinoma, Renal Cell
mRNA expression of matrix metalloproteases and their inhibitors differs in subtypes of renal cell carcinomas.
Carcinoma, Squamous Cell
Expression of human macrophage metalloelastase (MMP-12) by tumor cells in skin cancer.
Carcinoma, Squamous Cell
Expression of matrix metalloproteinase-12 is correlated with extracapsular spread of tumor from nodes with metastasis in head and neck squamous cell carcinoma.
Carcinoma, Squamous Cell
Metalloelastase (MMP-12) expression by tumour cells in squamous cell carcinoma of the vulva correlates with invasiveness, while that by macrophages predicts better outcome.
Cardiovascular Diseases
Development of Thioaryl-Based Matrix Metalloproteinase-12 Inhibitors with Alternative Zinc-Binding Groups: Synthesis, Potentiometric, NMR, and Crystallographic Studies.
Cardiovascular Diseases
Elevated Plasma Levels of MMP-12 Are Associated With Atherosclerotic Burden and Symptomatic Cardiovascular Disease in Subjects With Type 2 Diabetes.
Cardiovascular Diseases
Integrative studies implicate matrix metalloproteinase-12 as a culprit gene for large-artery atherosclerotic stroke.
Cardiovascular Diseases
Matrix metalloproteinase-12 cleaved fragment of titin as a predictor of functional capacity in patients with heart failure and preserved ejection fraction.
Cardiovascular Diseases
Matrix metalloproteinase-12 inhibitors: synthesis, structure-activity relationships and intestinal absorption of novel sugar-based biphenylsulfonamide carboxylates.
Cardiovascular Diseases
Pharmacogenetic associations of MMP9 and MMP12 variants with cardiovascular disease in patients with hypertension.
Cardiovascular Diseases
Sugar-Based Arylsulfonamide Carboxylates as Selective and Water-Soluble Matrix Metalloproteinase-12 Inhibitors.
Cardiovascular Diseases
The association between plasma proteomics and incident cardiovascular disease identifies MMP-12 as a promising cardiovascular risk marker in patients with chronic kidney disease.
Carotid Artery Diseases
Correlations of MMP-1, MMP-3, and MMP-12 with the degree of atherosclerosis, plaque stability and cardiovascular and cerebrovascular events.
Carotid Stenosis
MMP-12 and TIMP Behavior in Symptomatic and Asymptomatic Critical Carotid Artery Stenosis.
Celiac Disease
Metalloelastase (MMP-12) is upregulated in the gut of pediatric patients with potential celiac disease and in type 1 diabetes.
Central Nervous System Diseases
MMP-12, a Promising Therapeutic Target for Neurological Diseases.
Cerebral Infarction
Lack of independent relationship between the MMP-12 gene polymorphism and carotid plaques susceptibility in the Chinese Han population.
Cerebrovascular Disorders
Matrix metalloproteinase-1 and matrix metalloproteinase-12 gene polymorphisms and the risk of ischemic stroke in a Tunisian population.
Chondrosarcoma
Fluid shear promotes chondrosarcoma cell invasion by activating matrix metalloproteinase 12 via IGF-2 and VEGF signaling pathways.
Chondrosarcoma
Human macrophage metalloelastase (MMP-12) expression is induced in chondrocytes during fetal development and malignant transformation.
Chronic Periodontitis
Gene polymorphisms of matrix metalloproteinase-2, -9 and -12 in periodontal health and severe chronic periodontitis.
Chronic Periodontitis
[Analysis of salivary protease spectrum in chronic periodontitis].
Colitis
Matrix Metalloproteinase MMP-12 promotes macrophage transmigration across intestinal epithelial tight junctions and increases severity of experimental colitis.
Colitis, Ischemic
Distinct expression profiles of stromelysin-2 (MMP-10), collagenase-3 (MMP-13), macrophage metalloelastase (MMP-12), and tissue inhibitor of metalloproteinases-3 (TIMP-3) in intestinal ulcerations.
Colitis, Ulcerative
Distinct expression profiles of stromelysin-2 (MMP-10), collagenase-3 (MMP-13), macrophage metalloelastase (MMP-12), and tissue inhibitor of metalloproteinases-3 (TIMP-3) in intestinal ulcerations.
Colitis, Ulcerative
Predicting disease course in ulcerative colitis using stool proteins identified through an aptamer-based screen.
Colonic Neoplasms
Effects of Macrophage Metalloelastase on the Basic Fibroblast Growth Factor Expression and Tumor Angiogenesis in Murine Colon Cancer.
Colonic Neoplasms
Elastin is a key factor of tumor development in colorectal cancer.
Colonic Neoplasms
Mouse macrophage metalloelastase gene delivery by HVJ-cationic liposomes in experimental antiangiogenic gene therapy for murine CT-26 colon cancer.
Colonic Neoplasms
Mouse macrophage metalloelastase generates angiostatin from plasminogen and suppresses tumor angiogenesis in murine colon cancer.
Colonic Neoplasms
Serotonin regulates macrophage-mediated angiogenesis in a mouse model of colon cancer allografts.
Colonic Neoplasms
Serum MMP7, MMP10 and MMP12 level as negative prognostic markers in colon cancer patients.
Colonic Neoplasms
Transfection of mouse macrophage metalloelastase gene into murine CT-26 colon cancer cells suppresses orthotopic tumor growth, angiogenesis and vascular endothelial growth factor expression.
Colorectal Neoplasms
Clinical implications of matrix metalloproteinase-1, -3, -7, -9, -12, and plasminogen activator inhibitor-1 gene polymorphisms in colorectal cancer.
Colorectal Neoplasms
Gene polymorphism of matrix metalloproteinase-12 and -13 and association with colorectal cancer in Swedish patients.
Colorectal Neoplasms
Human macrophage metalloelastase gene expression in colorectal carcinoma and its clinicopathologic significance.
Colorectal Neoplasms
Role of matrix metalloproteinases (MMPs) in colorectal cancer.
Congenital Abnormalities
Expression of macrophage elastase (MMP12) in rat tail intervertebral disc and growth plate after asymmetric loading.
Congenital Abnormalities
Imbalanced MMP-3 and MMP-12 serum levels in systemic lupus erythematosus patients with Jaccoud's arthropathy and a distinctive MRI pattern.
Corneal Injuries
Protective effects of matrix metalloproteinase-12 following corneal injury.
Corneal Neovascularization
MMP12 Inhibits Corneal Neovascularization and Inflammation through Regulation of CCL2.
Coronary Artery Disease
Allele-specific regulation of matrix metalloproteinase-12 gene activity is associated with coronary artery luminal dimensions in diabetic patients with manifest coronary artery disease.
Coronary Artery Disease
Influence of matrix metalloproteinase genotype on cardiovascular disease susceptibility and outcome.
Coronary Artery Disease
Matrix metalloproteinase-1 and matrix metalloproteinase-12 gene polymorphisms and the outcome of coronary artery disease.
Coronary Artery Disease
Polymorphisms in the promoter regions of MMP-2, MMP-3, MMP-9 and MMP-12 genes as determinants of aneurysmal coronary artery disease.
Cough
Induction and regulation of matrix metalloproteinase-12 in human airway smooth muscle cells.
COVID-19
Matrix metalloproteinases are involved in the development of neurological complications in patients with Coronavirus disease 2019.
COVID-19
Revisiting matrix metalloproteinase 12: its role in pathophysiology of asthma and related pulmonary diseases.
Craniopharyngioma
MMP12 is a potential therapeutic target for Adamantinomatous craniopharyngioma: Conclusions from bioinformatics analysis and in vitro experiments.
Crohn Disease
Distinct expression profiles of stromelysin-2 (MMP-10), collagenase-3 (MMP-13), macrophage metalloelastase (MMP-12), and tissue inhibitor of metalloproteinases-3 (TIMP-3) in intestinal ulcerations.
Crohn Disease
Predicting disease course in ulcerative colitis using stool proteins identified through an aptamer-based screen.
Crohn Disease
Stromelysin-1 and macrophage metalloelastase expression in the intestinal mucosa of Crohn's disease patients treated with infliximab.
Cutis Laxa
Cutis Laxa: analysis of metalloproteinases and extracellular matrix expression by immunohistochemistry and histochemistry.
Cystic Fibrosis
Neutrophil elastase and matrix metalloproteinase 12 in cystic fibrosis lung disease.
Dehydration
Airway Mucus Obstruction Triggers Macrophage Activation and MMP12-dependent Emphysema.
Dehydration
RNA sequencing identifies transcriptional changes in the rabbit larynx in response to low humidity challenge.
Demyelinating Diseases
Delayed Astrogliosis Associated with Reduced M1 Microglia Activation in Matrix Metalloproteinase 12 Knockout Mice during Theiler's Murine Encephalomyelitis.
Demyelinating Diseases
Locating the Site of Neuropathic Pain In Vivo Using MMP-12-Targeted Magnetic Nanoparticles.
Demyelinating Diseases
Matrix metalloproteinase-12 deficiency ameliorates the clinical course and demyelination in Theiler's murine encephalomyelitis.
Demyelinating Diseases
Matrix metalloproteinase-12 is expressed in phagocytotic macrophages in active multiple sclerosis lesions.
Demyelinating Diseases
MMP-12, MMP-3, and TIMP-1 are markedly upregulated in chronic demyelinating theiler murine encephalomyelitis.
Dermatitis Herpetiformis
Enhanced expression of human metalloelastase (MMP-12) in cutaneous granulomas and macrophage migration.
Dermatitis Herpetiformis
Parallel expression of macrophage metalloelastase (MMP-12) in duodenal and skin lesions of patients with dermatitis herpetiformis.
Dermatitis, Allergic Contact
Roles of alternatively activated M2 macrophages in allergic contact dermatitis.
Dermatitis, Contact
Matrix metalloproteinase 12 is produced by M2 macrophages and plays important roles in the development of contact hypersensitivity.
Dermatitis, Contact
Roles of alternatively activated M2 macrophages in allergic contact dermatitis.
Dermatitis, Contact
SOCS3 Expressed in M2 Macrophages Attenuates Contact Hypersensitivity by Suppressing MMP-12 Production.
Diabetes Mellitus
Matrix metalloproteinase-1 and matrix metalloproteinase-12 gene polymorphisms and the risk of ischemic stroke in a Tunisian population.
Diabetes Mellitus, Type 1
Metalloelastase (MMP-12) is upregulated in the gut of pediatric patients with potential celiac disease and in type 1 diabetes.
Diabetes Mellitus, Type 2
Elevated Plasma Levels of MMP-12 Are Associated With Atherosclerotic Burden and Symptomatic Cardiovascular Disease in Subjects With Type 2 Diabetes.
Diabetes Mellitus, Type 2
Matrix metalloproteinase-1 and matrix metalloproteinase-12 gene polymorphisms and the risk of ischemic stroke in a Tunisian population.
Duodenal Ulcer
[Role of Allelic Genes of Matrix Metalloproteinases and Their Tissue Inhibitors in the Peptic Ulcer Disease Development].
Dyslipidemias
The effect of obesity and tobacco smoke exposure on inflammatory mediators and matrix metalloproteinases in rat model.
Encephalitis
Chemokines and matrix metalloproteinases in cerebrospinal fluid of patients with central nervous system complications caused by varicella-zoster virus.
Encephalitis
Expression of matrix metalloproteinases and their tissue inhibitor during viral encephalitis.
Encephalomyelitis
Cleavage of osteopontin by matrix metalloproteinase-12 modulates experimental autoimmune encephalomyelitis disease in C57BL/6 mice.
Encephalomyelitis
Delayed Astrogliosis Associated with Reduced M1 Microglia Activation in Matrix Metalloproteinase 12 Knockout Mice during Theiler's Murine Encephalomyelitis.
Encephalomyelitis
Expression and regulation of matrix metalloproteinase-12 in experimental autoimmune encephalomyelitis and by bone marrow derived macrophages in vitro.
Encephalomyelitis
Matrix metalloproteinase-12 deficiency ameliorates the clinical course and demyelination in Theiler's murine encephalomyelitis.
Encephalomyelitis
Matrix metalloproteinase-12 deficiency worsens relapsing-remitting experimental autoimmune encephalomyelitis in association with cytokine and chemokine dysregulation.
Encephalomyelitis
MMP-12, MMP-3, and TIMP-1 are markedly upregulated in chronic demyelinating theiler murine encephalomyelitis.
Encephalomyelitis, Autoimmune, Experimental
Cleavage of osteopontin by matrix metalloproteinase-12 modulates experimental autoimmune encephalomyelitis disease in C57BL/6 mice.
Encephalomyelitis, Autoimmune, Experimental
Expression and regulation of matrix metalloproteinase-12 in experimental autoimmune encephalomyelitis and by bone marrow derived macrophages in vitro.
Encephalomyelitis, Autoimmune, Experimental
Matrix metalloproteinase-12 deficiency worsens relapsing-remitting experimental autoimmune encephalomyelitis in association with cytokine and chemokine dysregulation.
Endometrial Neoplasms
Increased expression of human macrophage metalloelastase (MMP-12) is associated with the invasion of endometrial adenocarcinoma.
Endometriosis
Genetic polymorphisms of matrix metalloproteinase 12 and 13 genes are implicated in endometriosis progression.
Endometriosis
[Association of matrix metalloproteinases' polymorphisms of MMP3 and MMP9 with development of genital endometriosis].
Endotoxemia
Synthesis and Validation of a Hydroxypyrone-Based, Potent, and Specific Matrix Metalloproteinase-12 Inhibitor with Anti-Inflammatory Activity In Vitro and In Vivo.
Enterocolitis, Necrotizing
Matrilysins-1 and -2 (MMP-7 and -26) and metalloelastase (MMP-12), unlike MMP-19, are up-regulated in necrotizing enterocolitis.
Eosinophilia
Eosinophil-derived IL-13 Promotes Emphysema.
Eosinophilia
Interleukin-13-dependent expression of matrix metalloproteinase-12 is required for the development of airway eosinophilia in mice.
Esophageal Squamous Cell Carcinoma
Clinicopathological significance of human macrophage metalloelastase expression in esophageal squamous cell carcinoma.
Esophageal Squamous Cell Carcinoma
The influence of matrix metalloproteinase-2, -9, and -12 promoter polymorphisms on Iranian patients with oesophageal squamous cell carcinoma.
Esophageal Squamous Cell Carcinoma
The overexpression and predictive significance of MMP-12 in esophageal squamous cell carcinoma.
Exanthema
Differential Gene Expression in Erlotinib-treated Fibroblasts.
Exanthema
Parallel expression of macrophage metalloelastase (MMP-12) in duodenal and skin lesions of patients with dermatitis herpetiformis.
Fibromatosis, Aggressive
Invasion and MMP expression profile in desmoid tumours.
Fibromatosis, Gingival
The Effect of MMP-13, MMP-12, and AMBN on Gingival Enlargement and Root Deformation In a New Type of Gingival Fibromatosis.
Fibrosarcoma
Identification of matrix metalloproteinase inhibitors by chemical arrays.
Gallbladder Neoplasms
Identification of LIFR, PIK3R1, and MMP12 as Novel Prognostic Signatures in Gallbladder Cancer Using Network-Based Module Analysis.
Giant Cell Arteritis
MMP-12, a novel matrix metalloproteinase associated with giant cell arteritis.
Gingival Overgrowth
The Effect of MMP-13, MMP-12, and AMBN on Gingival Enlargement and Root Deformation In a New Type of Gingival Fibromatosis.
Glaucoma, Open-Angle
Altered Expression Levels of MMP1, MMP9, MMP12, TIMP1, and IL-1? as a Risk Factor for the Elevated IOP and Optic Nerve Head Damage in the Primary Open-Angle Glaucoma Patients.
Glaucoma, Open-Angle
The MMP1, MMP9, MMP12, IL-1? and TIMP1 gene polymorphisms and the risk of primary open-angle glaucoma.
Glioblastoma
Expression of matrix metalloproteinases and their inhibitors in human brain tumors.
Glioblastoma
Mediators of glioblastoma resistance and invasion during antivascular endothelial growth factor therapy.
Glioblastoma
Tenascin-C stimulates glioma cell invasion through matrix metalloproteinase-12.
Glioma
Reduction of protein kinase C delta attenuates tenascin-C stimulated glioma invasion in three-dimensional matrix.
Glioma
Stictamides A-C, MMP12 inhibitors containing 4-amino-3-hydroxy-5-phenylpentanoic acid subunits.
Glioma
Tenascin-C stimulates glioma cell invasion through matrix metalloproteinase-12.
Glomerulonephritis
Genetic loci modulate macrophage activity and glomerular damage in experimental glomerulonephritis.
Glomerulonephritis
Macrophage metalloelastase as a major factor for glomerular injury in anti-glomerular basement membrane nephritis.
Glomerulonephritis
Matrix metalloproteinase 12 modulates high-fat-diet induced glomerular fibrogenesis and inflammation in a mouse model of obesity.
Glomerulonephritis
Matrix metalloproteinase-12 (MMP-12) deficiency attenuates experimental crescentic anti-GBM glomerulonephritis.
Granuloma
Enhanced expression of human metalloelastase (MMP-12) in cutaneous granulomas and macrophage migration.
Granuloma
Exposure to a Mycobacterial Antigen, ESAT-6, Exacerbates Granulomatous and Fibrotic Changes in a Multiwall Carbon Nanotube Model of Chronic Pulmonary Disease.
Granuloma
Genomics of foam cells and nonfoamy macrophages from rabbits identifies arginase-I as a differential regulator of nitric oxide production.
Granuloma
Macrophage-specific overexpression of human matrix metalloproteinase-12 in transgenic rabbits.
Granuloma
Matrix Metalloproteinase-12 Is Required for Granuloma Progression.
Granuloma
Studies in a Murine Granuloma Model of Instilled Carbon Nanotubes: Relevance to Sarcoidosis.
Granuloma Annulare
Enhanced expression of human metalloelastase (MMP-12) in cutaneous granulomas and macrophage migration.
Heart Failure
Circulating proteins as predictors of incident heart failure in the elderly.
Heart Failure
Matrix metalloproteinase-12 cleaved fragment of titin as a predictor of functional capacity in patients with heart failure and preserved ejection fraction.
Heart Failure
Selective MMP-12 inhibitors: WO-2008057254.
Histiocytoma, Benign Fibrous
The Immunological Roles of Periostin/Tumor-Associated Macrophage Axis in Development of Dermatofibrosarcoma Protuberans.
Histiocytosis
Prognostic significance of gelsolin and MMP12 in Langerhans cell histiocytosis.
Histiocytosis, Langerhans-Cell
Prognostic significance of gelsolin and MMP12 in Langerhans cell histiocytosis.
Hypercholesterolemia
Effect of a synthetic matrix metalloproteinase inhibitor (ONO-4817) on neointima formation in hypercholesterolemic hamsters.
Hypertension
Corrigendum to "Elevated 20-HETE in metabolic syndrome regulates arterial stiffness and systolic hypertension via MMP12 activation" [J. Mol. Cell. Cardiol. 117 (2018) 88-99].
Hypertension
Elevated 20-HETE in metabolic syndrome regulates arterial stiffness and systolic hypertension via MMP12 activation.
Hypertension
Pharmacogenetic associations of MMP9 and MMP12 variants with cardiovascular disease in patients with hypertension.
Hypertension, Pulmonary
Series "matrix metalloproteinases in lung health and disease": Matrix metalloproteinases in COPD.
Idiopathic Pulmonary Fibrosis
Revisiting matrix metalloproteinase 12: its role in pathophysiology of asthma and related pulmonary diseases.
Infarction, Middle Cerebral Artery
Post-stroke mRNA expression profile of MMPs: effect of genetic deletion of MMP-12.
Infections
Elevated concentrations of matrix metalloproteinase-12 and elastin degradation products in the sera of pregnant women infected with Toxoplasma gondii.
Infections
Experimental Pneumocystis lung infection promotes M2a alveolar macrophage-derived MMP12 production.
Infections
Expression of matrix metalloproteinases and their tissue inhibitor during viral encephalitis.
Infections
Infection of Mycobacterium tuberculosis Promotes Both M1/M2 Polarization and MMP Production in Cigarette Smoke-Exposed Macrophages.
Infections
Inflammation and emphysema in cigarette smoke-exposed mice when instilled with poly (I:C) or infected with influenza A or respiratory syncytial viruses.
Infections
Macrophage elastase prevents Gemella morbillorum infection and improves outcome following murine bone marrow transplantation.
Infections
Matrix metalloproteinase 12-deficiency augments extracellular matrix degrading metalloproteinases and attenuates IL-13-dependent fibrosis.
Infections
Matrix metalloproteinase expression correlates with virulence following neurotropic mouse hepatitis virus infection.
Infections
MMP-12, MMP-3, and TIMP-1 are markedly upregulated in chronic demyelinating theiler murine encephalomyelitis.
Infections
MMP-12-mediated by SARM-TRIF signaling pathway contributes to IFN-¿-independent airway inflammation and AHR post RSV infection in nude mice.
Infections
Nonchromogenic hydrolysis of elastase and cathepsin G p-nitroanilide substrates by Pseudomonas aeruginosa elastase.
Infections
Parvovirus B19 activates in vitro normal human dermal fibroblasts: a possible implication in skin fibrosis and systemic sclerosis.
Infections
Pathophysiological changes induced by Pseudomonas aeruginosa infection are involved in MMP-12 and MMP-13 upregulation in human carcinoma epithelial cells and a pneumonia mouse model.
Infections
Pneumococcal Infection Aggravates Elastase-Induced Emphysema via Matrix Metalloproteinase 12 Overexpression.
Infections
Pulmonary C Fibers Modulate MMP-12 Production via PAR2 and Are Involved in the Long-Term Airway Inflammation and Airway Hyperresponsiveness Induced by Respiratory Syncytial Virus Infection.
Infections
The immuno-pathogenesis of progressive scarring trachoma: results of a four-year longitudinal study in Tanzanian children.
Infections
The Role of Matrix Metalloproteinases in Development, Repair, and Destruction of the Lungs.
Infections
Transcriptomic analysis identifies upregulation of secreted phosphoprotein 1 in silicotic rats.
Infections
Type III Secretion System of Pseudomonas aeruginosa Affects Matrix Metalloproteinase 12 (MMP-12) and MMP-13 Expression via Nuclear Factor ?B Signaling in Human Carcinoma Epithelial Cells and a Pneumonia Mouse Model.
Inflammatory Bowel Diseases
Matrix Metalloproteinase MMP-12 promotes macrophage transmigration across intestinal epithelial tight junctions and increases severity of experimental colitis.
Inflammatory Bowel Diseases
Solution structure of inhibitor-free human metalloelastase (MMP-12) indicates an internal conformational adjustment.
Insulin Resistance
Macrophage metalloelastase (MMP12) regulates adipose tissue expansion, insulin sensitivity, and expression of inducible nitric oxide synthase.
Intervertebral Disc Degeneration
Matrix metalloproteinase 12 is an indicator of intervertebral disc degeneration co-expressed with fibrotic markers.
Intervertebral Disc Degeneration
Matrix metalloproteinase-12 immunolocalization in the degenerating human intervertebral disc and sand rat spine: Biologic implications.
Ischemic Attack, Transient
Differences in matrix metalloproteinase-1 and matrix metalloproteinase-12 transcript levels among carotid atherosclerotic plaques with different histopathological characteristics.
Ischemic Stroke
Causal Effect of MMP-1 (Matrix Metalloproteinase-1), MMP-8, and MMP-12 Levels on Ischemic Stroke: A Mendelian Randomization Study.
Ischemic Stroke
Integrative studies implicate matrix metalloproteinase-12 as a culprit gene for large-artery atherosclerotic stroke.
Ischemic Stroke
Matrix metalloproteinase-1 and matrix metalloproteinase-12 gene polymorphisms and the risk of ischemic stroke in a Tunisian population.
Ischemic Stroke
Matrix Metalloproteinase-12 Induces Blood-Brain Barrier Damage After Focal Cerebral Ischemia.
Ischemic Stroke
MMP Gene Polymorphisms, MMP-1 -1607 1G/2G, -519 A/G, and MMP-12 -82 A/G, and Ischemic Stroke: A Meta-Analysis.
Ischemic Stroke
MMP-12 as a potential biomarker to forecast ischemic stroke in obese patients.
Ischemic Stroke
Post-transcriptional inactivation of matrix metalloproteinase-12 after focal cerebral ischemia attenuates brain damage.
Joint Diseases
Imbalanced MMP-3 and MMP-12 serum levels in systemic lupus erythematosus patients with Jaccoud's arthropathy and a distinctive MRI pattern.
Joint Diseases
Overexpression of human matrix metalloproteinase-12 enhances the development of inflammatory arthritis in transgenic rabbits.
Kallmann Syndrome
Cigarette smoke modulates PC3 prostate cancer cell migration by altering adhesion molecules and the extracellular matrix.
Keratosis
Analysis of SDHD and MMP12 in an affected solar keratosis and control cohort.
Kidney Diseases
Expression of macrophage metalloelastase (MMP-12) in podocytes of hereditary nephrotic mice (ICGN strain).
Liver Cirrhosis
Elastin accumulation is regulated at the level of degradation by macrophage metalloelastase (MMP-12) during experimental liver fibrosis.
Liver Cirrhosis
Gliptins Suppress Inflammatory Macrophage Activation to Mitigate Inflammation, Fibrosis, Oxidative Stress, and Vascular Dysfunction in Models of Nonalcoholic Steatohepatitis and Liver Fibrosis.
Liver Cirrhosis
MMP-12 regulates proliferation of mouse macrophages via?the ERK/P38?MAPK?pathways during inflammation.
Liver Cirrhosis
Phenotypic and functional characterization of macrophages with therapeutic potential generated from human cirrhotic monocytes in a cohort study.
Liver Neoplasms
Role of Matrix Metallopeptidase 12 in the Development of Hepatocellular Carcinoma.
Lung Diseases
Airway Mucus Obstruction Triggers Macrophage Activation and MMP12-dependent Emphysema.
Lung Diseases
Evidence for early fibrosis and increased airway resistance in bone marrow transplant recipient mice deficient in MMP12.
Lung Diseases
Loss of integrin alpha(v)beta6-mediated TGF-beta activation causes Mmp12-dependent emphysema.
Lung Diseases
Neutrophil elastase and matrix metalloproteinase 12 in cystic fibrosis lung disease.
Lung Diseases
Optimization of total protein and activity assays for the detection of MMP-12 in induced human sputum.
Lung Diseases
Revisiting matrix metalloproteinase 12: its role in pathophysiology of asthma and related pulmonary diseases.
Lung Diseases
Role of recently migrated monocytes in cigarette smoke-induced lung inflammation in different strain of mice.
Lung Diseases
Single-walled carbon nanotubes induce airway hyperreactivity and parenchymal injury in mice.
Lung Diseases
The Role of Matrix Metalloproteinases in Development, Repair, and Destruction of the Lungs.
Lung Diseases, Interstitial
Changes in collagen metabolism and proteinolysis after repeated inhalation exposure to ozone.
Lung Diseases, Interstitial
Increased serum levels and tissue expression of matrix metalloproteinase-12 in patients with systemic sclerosis: correlation with severity of skin and pulmonary fibrosis and vascular damage.
Lung Injury
Analysis of the inflammatory response induced by rhMMP-12 catalytic domain instilled in mouse airways.
Lung Injury
Effect of Yangyinqingfei decoction on radiation-induced lung injury via downregulation of MMP12 and TIMP-1 expression.
Lung Injury
Evidence for early fibrosis and increased airway resistance in bone marrow transplant recipient mice deficient in MMP12.
Lung Injury
Extracellular matrix remodeling genes polymorphisms and risk of chronic bronchitis and recurrent pneumonia in children.
Lung Injury
Genetic polymorphisms of matrix metalloproteinases: functional importance in the development of chronic obstructive pulmonary disease?
Lung Injury
Macrophage infiltration and renal damage are independent of Matrix Metalloproteinase 12 (MMP-12) in the obstructed kidney.
Lung Injury
Role of metalloelastase in a model of allergic lung responses induced by cockroach allergen.
Lung Injury
The role of matrix metalloproteinase polymorphisms in the rate of decline in lung function.
Lung Injury
The role of metalloelastase in immune complex-induced acute lung injury.
Lung Neoplasms
Analysis of host- and tumor-derived proteinases using a custom dual species microarray reveals a protective role for stromal matrix metalloproteinase-12 in non-small cell lung cancer.
Lung Neoplasms
Effect of lentivirus-mediated integrin ?V?3-shRNA on tumor growth of mice with lung cancer xenografts.
Lung Neoplasms
Genotypes and haplotypes of matrix metalloproteinase 1, 3 and 12 genes and the risk of lung cancer.
Lung Neoplasms
Macrophage Elastase Induces TRAIL-mediated Tumor Cell Death Through its Carboxyterminal Domain.
Lung Neoplasms
Matrix metalloproteinase 12 overexpression in lung epithelial cells plays a key role in emphysema to lung bronchioalveolar adenocarcinoma transition.
Lung Neoplasms
Matrix metalloproteinase 12 promotes tumor propagation in the lung.
Lung Neoplasms
Matrix metalloproteinase family gene polymorphisms and lung cancer susceptibility: an updated meta-analysis.
Lung Neoplasms
Matrix metalloproteinase-12 expression correlates with local recurrence and metastatic disease in non-small cell lung cancer patients.
Lung Neoplasms
MMP expression profiling in recurred stage IB lung cancer.
Lung Neoplasms
On the "TRAIL" of a Killer: MMP12 in Lung Cancer.
Lung Neoplasms
SNPs in matrix metalloproteinase genes and lung cancer chemotherapy response and prognosis.
Lung Neoplasms
T-box transcription factor brachyury promotes tumor cell invasion and metastasis in non-small cell lung cancer via upregulation of matrix metalloproteinase 12.
Lung Neoplasms
[Research progress of matrix metalloproteinase 12 in non-small cell lung cancer].
Lupus Erythematosus, Systemic
C-terminal truncation of IFN-? inhibits proinflammatory macrophage responses and is deficient in autoimmune disease.
Lupus Erythematosus, Systemic
Distinct gene expression of osteopontin in patients with ulcerative colitis.
Lupus Erythematosus, Systemic
Imbalanced MMP-3 and MMP-12 serum levels in systemic lupus erythematosus patients with Jaccoud's arthropathy and a distinctive MRI pattern.
Lupus Erythematosus, Systemic
Transcriptomic analysis identifies upregulation of secreted phosphoprotein 1 in silicotic rats.
Lymphatic Metastasis
Matrix metalloproteinase-12 is associated with overall survival in Chinese patients with gastric cancer.
macrophage elastase deficiency
Candidate SNP Markers of Atherogenesis Significantly Shifting the Affinity of TATA-Binding Protein for Human Gene Promoters show stabilizing Natural Selection as a Sum of Neutral Drift Accelerating Atherogenesis and Directional Natural Selection Slowing It.
macrophage elastase deficiency
Delayed Astrogliosis Associated with Reduced M1 Microglia Activation in Matrix Metalloproteinase 12 Knockout Mice during Theiler's Murine Encephalomyelitis.
macrophage elastase deficiency
Expression of MMP-12 after neonatal hypoxic-ischemic brain injury in mice.
macrophage elastase deficiency
Loss of matrix metalloproteinase-9 or matrix metalloproteinase-12 protects apolipoprotein E-deficient mice against atherosclerotic media destruction but differentially affects plaque growth.
macrophage elastase deficiency
Macrophage metalloelastase (MMP-12) deficiency does not alter bleomycin-induced pulmonary fibrosis in mice.
macrophage elastase deficiency
Matrix metalloproteinase-12 contributes to neuroinflammation in the aged brain.
macrophage elastase deficiency
Matrix metalloproteinase-12 deficiency ameliorates the clinical course and demyelination in Theiler's murine encephalomyelitis.
macrophage elastase deficiency
Matrix metalloproteinase-12 deficiency worsens relapsing-remitting experimental autoimmune encephalomyelitis in association with cytokine and chemokine dysregulation.
macrophage elastase deficiency
MMP-12 deficiency attenuates angiotensin II-induced vascular injury, M2 macrophage accumulation, and skin and heart fibrosis.
macrophage elastase deficiency
MMP-12 has a role in abdominal aortic aneurysms in mice.
macrophage elastase deficiency
Pathogenesis of aortic dilatation in mucopolysaccharidosis VII mice may involve complement activation.
macrophage elastase deficiency
TGF-beta activity protects against inflammatory aortic aneurysm progression and complications in angiotensin II-infused mice.
Melanoma
Matrix metalloproteinase-12 expression is increased in cutaneous melanoma and associated with tumor aggressiveness.
Melanoma
Melanoma cell therapy: Endothelial progenitor cells as shuttle of the MMP12 uPAR-degrading enzyme.
Melanoma
Mouse macrophage metalloelastase gene delivery by HVJ-cationic liposomes in experimental antiangiogenic gene therapy for murine CT-26 colon cancer.
Melanoma
Mouse macrophage metalloelastase gene transfer into a murine melanoma suppresses primary tumor growth by halting angiogenesis.
Meningioma
Expression of matrix metalloproteinases and their inhibitors in human brain tumors.
Meningitis
Chemokines and matrix metalloproteinases in cerebrospinal fluid of patients with central nervous system complications caused by varicella-zoster virus.
Meningitis
Matrix metalloproteinase-12 leads to elastin degradation in BALB/c mice with eosinophilic meningitis caused by Angiostrongylus cantonensis.
Metabolic Syndrome
Corrigendum to "Elevated 20-HETE in metabolic syndrome regulates arterial stiffness and systolic hypertension via MMP12 activation" [J. Mol. Cell. Cardiol. 117 (2018) 88-99].
Metabolic Syndrome
Elevated 20-HETE in metabolic syndrome regulates arterial stiffness and systolic hypertension via MMP12 activation.
Mouth Neoplasms
Matrix metalloproteinases (MMP) 1 and MMP10 but not MMP12 are potential oral cancer markers.
Multiple Sclerosis
Association of MMP1, MMP3, MMP9, and MMP12 polymorphisms with risk and clinical course of multiple sclerosis in a Polish population.
Multiple Sclerosis
Matrix metalloproteinase-12 deficiency worsens relapsing-remitting experimental autoimmune encephalomyelitis in association with cytokine and chemokine dysregulation.
Multiple Sclerosis
Matrix metalloproteinase-12 is expressed in phagocytotic macrophages in active multiple sclerosis lesions.
Multiple Sclerosis
MMP-12, a Promising Therapeutic Target for Neurological Diseases.
Myocardial Infarction
Expression of matrix metalloproteinases-12 in ST-segment elevation myocardial infarction: A case-control study.
Myocardial Infarction
Influence of matrix metalloproteinase-12 on fibrinogen level.
Myocardial Infarction
Inhibition of plasminogen activators or matrix metalloproteinases prevents cardiac rupture but impairs therapeutic angiogenesis and causes cardiac failure.
Myocardial Infarction
Matrix metalloproteinase-12 as an endogenous resolution promoting factor following myocardial infarction.
Myocardial Infarction
Matrix metalloproteinase-12 produced by Ly6Clow macrophages prolongs the survival after myocardial infarction by preventing neutrophil influx.
Myocardial Infarction
MMP-12 regulates proliferation of mouse macrophages via?the ERK/P38?MAPK?pathways during inflammation.
Myocardial Infarction
[The Association of Gene Polymorphisms of Matrix Metalloproteinases (-9, -12 and -20) and Collagen Type I Degradation Products With the Remodeling of the Left Ventricle in Patients With Acute Myocardial Infarction].
Myocarditis
Neutralizing anti-4-1BBL treatment improves cardiac function in viral myocarditis.
Nasal Polyps
Involvement of the extracellular matrix proteins periostin and tenascin C in nasal polyp remodeling by regulating the expression of MMPs.
Nasopharyngeal Carcinoma
Matrix metalloproteinase 12 is induced by heterogeneous nuclear ribonucleoprotein K and promotes migration and invasion in nasopharyngeal carcinoma.
Nasopharyngeal Carcinoma
Regulation of matrix metalloproteinase-1 by Epstein-Barr virus proteins.
Necrobiosis Lipoidica
Enhanced expression of human metalloelastase (MMP-12) in cutaneous granulomas and macrophage migration.
Neoplasm Metastasis
A ten-gene methylation signature as a novel biomarker for improving prediction of prognosis and indicating gene targets in endometrial cancer.
Neoplasm Metastasis
Aromatase-induced endogenous estrogen promotes tumour metastasis through estrogen receptor-?/matrix metalloproteinase 12 axis activation in castration-resistant prostate cancer.
Neoplasm Metastasis
Clinical implications of matrix metalloproteinase-1, -3, -7, -9, -12, and plasminogen activator inhibitor-1 gene polymorphisms in colorectal cancer.
Neoplasm Metastasis
Expression of matrix metalloproteinase-12 is correlated with extracapsular spread of tumor from nodes with metastasis in head and neck squamous cell carcinoma.
Neoplasm Metastasis
Fluid shear promotes chondrosarcoma cell invasion by activating matrix metalloproteinase 12 via IGF-2 and VEGF signaling pathways.
Neoplasm Metastasis
Knockdown of MMP12 inhibits the growth and invasion of lung adenocarcinoma cells.
Neoplasm Metastasis
Macrophage elastase (matrix metalloproteinase-12) suppresses growth of lung metastases.
Neoplasm Metastasis
Macrophage Elastase Induces TRAIL-mediated Tumor Cell Death Through its Carboxyterminal Domain.
Neoplasm Metastasis
Macrophage metalloelastase (MME) as adjuvant for intra-tumoral injection of oncolytic adenovirus and its influence on metastases development.
Neoplasm Metastasis
Matrix metalloproteinase-12 expression is increased in cutaneous melanoma and associated with tumor aggressiveness.
Neoplasm Metastasis
Matrix metalloproteinase-12 is associated with overall survival in Chinese patients with gastric cancer.
Neoplasm Metastasis
Metalloelastase (MMP-12) expression by tumour cells in squamous cell carcinoma of the vulva correlates with invasiveness, while that by macrophages predicts better outcome.
Neoplasm Metastasis
MTA2 silencing attenuates the metastatic potential of cervical cancer cells by inhibiting AP1-mediated MMP12 expression via the ASK1/MEK3/p38/YB1 axis.
Neoplasm Metastasis
Optimizing the Diagnostic Role of Alpha-Fetoprotein and Abdominal Ultrasound by Adding Overexpressed Blood mRNA Matrix Metalloproteinase-12 for Diagnosis of HCV-Related Hepatocellular Carcinoma.
Neoplasm Metastasis
Prognostic values of matrix metalloproteinase family expression in human colorectal carcinoma.
Neoplasm Metastasis
Role of miR-647 in human gastric cancer suppression.
Neoplasm Metastasis
T-box transcription factor brachyury promotes tumor cell invasion and metastasis in non-small cell lung cancer via upregulation of matrix metalloproteinase 12.
Neoplasm Metastasis
The overexpression and predictive significance of MMP-12 in esophageal squamous cell carcinoma.
Neoplasm Metastasis
Transcriptomic and microRNA Expression Profiles Identify Biomarkers for Predicting Neo-Chemoradiotherapy Response in Esophageal Squamous Cell Carcinomas (ESCC).
Neoplasm Metastasis
Upregulation and differential expression of matrilysin (MMP-7) and metalloelastase (MMP-12) and their inhibitors TIMP-1 and TIMP-3 in Barrett's oesophageal adenocarcinoma.
Neoplasm Metastasis
[Study on the expression of matrix metalloproteinase-12 and NM_002426 in squamous laryngeal carcinoma]
Neoplasm Micrometastasis
Macrophage elastase (matrix metalloproteinase-12) suppresses growth of lung metastases.
Neoplasms
A chinese herbal formula ameliorates COPD by inhibiting the inflammatory response via downregulation of p65, JNK, and p38.
Neoplasms
A pan-cancer perspective of matrix metalloproteases (MMP) gene expression profile and their diagnostic/prognostic potential.
Neoplasms
Activation of inflammatory mediators and potential role of ah-receptor ligands in foam cell formation.
Neoplasms
Additional MDA-MB-231 breast cancer cell matrix metalloproteinases promote invasiveness.
Neoplasms
Albumin Urinary Excretion Is Associated with Increased Levels of Urinary Chemokines, Cytokines, and Growth Factors Levels in Humans.
Neoplasms
Analysis of host- and tumor-derived proteinases using a custom dual species microarray reveals a protective role for stromal matrix metalloproteinase-12 in non-small cell lung cancer.
Neoplasms
Aortic intramural hematoma associated with metastatic carcinoma.
Neoplasms
Aromatase-induced endogenous estrogen promotes tumour metastasis through estrogen receptor-?/matrix metalloproteinase 12 axis activation in castration-resistant prostate cancer.
Neoplasms
Biomarkers of blood cadmium and incidence of cardiovascular events in non-smokers: results from a population-based proteomics study.
Neoplasms
Blocking MMP-12-modulated epithelial-mesenchymal transition by repurposing penfluridol restrains lung adenocarcinoma metastasis via uPA/uPAR/TGF-?/Akt pathway.
Neoplasms
Cigarette smoke-induced pulmonary emphysema in scid-mice. Is the acquired immune system required?
Neoplasms
Circulating proteins as predictors of incident heart failure in the elderly.
Neoplasms
Clinicopathological significance of human macrophage metalloelastase expression in esophageal squamous cell carcinoma.
Neoplasms
Cloning, expression, purification, and characterization of rat MMP-12.
Neoplasms
Colony-stimulating factor-1 antibody reverses chemoresistance in human mcf-7 breast cancer xenografts.
Neoplasms
Colony-stimulating factor-1 blockade by antisense oligonucleotides and small interfering RNAs suppresses growth of human mammary tumor xenografts in mice.
Neoplasms
Cooverexpression of ERBB1 and ERBB4 receptors predicts poor clinical outcome in pN+ oral squamous cell carcinoma with extranodal spread.
Neoplasms
Diagnostic marker signature for esophageal cancer from transcriptome analysis.
Neoplasms
Differential expression of matrilysin-1 (MMP-7), 92 kD gelatinase (MMP-9), and metalloelastase (MMP-12) in oral verrucous and squamous cell cancer.
Neoplasms
Differential expression of matrix metalloproteinases and miRNAs in the metastasis of oral squamous cell carcinoma.
Neoplasms
Differential Gene Expression in Erlotinib-treated Fibroblasts.
Neoplasms
Effect of hirudin on the levels of acute lung injury rat tumor necrosis factor-? and matrix metalloproteinase-12.
Neoplasms
Effect of lentivirus-mediated integrin ?V?3-shRNA on tumor growth of mice with lung cancer xenografts.
Neoplasms
Effects of Macrophage Metalloelastase on the Basic Fibroblast Growth Factor Expression and Tumor Angiogenesis in Murine Colon Cancer.
Neoplasms
Endothelial progenitor cells-dependent angiogenesis requires localization of the full-length form of uPAR in caveolae.
Neoplasms
Endothelin receptor B protects granulocyte macrophage colony-stimulating factor mRNA from degradation.
Neoplasms
Expression of human macrophage metalloelastase (MMP-12) by tumor cells in skin cancer.
Neoplasms
Expression of human macrophage metalloelastase gene in hepatocellular carcinoma: correlation with angiostatin generation and its clinical significance.
Neoplasms
Expression of matrix metalloproteinase-12 in aortic dissection.
Neoplasms
Expression of matrix metalloproteinase-12 is correlated with extracapsular spread of tumor from nodes with metastasis in head and neck squamous cell carcinoma.
Neoplasms
Expression of matrix metalloproteinases and their inhibitors in human brain tumors.
Neoplasms
Expression of most matrix metalloproteinase family members in breast cancer represents a tumor-induced host response.
Neoplasms
Fine particulate matter exposure promotes M2 macrophage polarization through inhibiting histone deacetylase 2 in the pathogenesis of chronic obstructive pulmonary disease.
Neoplasms
Glucocorticoid-regulated gene expression during cutaneous wound repair.
Neoplasms
High serum cytokine levels may predict the responsiveness of patients with severe asthma to benralizumab.
Neoplasms
Human bronchial epithelial cells express and secrete MMP-12.
Neoplasms
Human macrophage metalloelastase (MMP-12) expression is induced in chondrocytes during fetal development and malignant transformation.
Neoplasms
Human macrophage metalloelastase expression in gastric cancer and its relationship with gastric cancer prognosis.
Neoplasms
Human macrophage metalloelastase gene expression in colorectal carcinoma and its clinicopathologic significance.
Neoplasms
Hydrogen coadministration slows the development of COPD-like lung disease in a cigarette smoke-induced rat model.
Neoplasms
Identification of targets for rational pharmacological therapy in childhood craniopharyngioma.
Neoplasms
Immunohistochemical study of tumor necrosis factor-alpha, matrix metalloproteinase-12, and tissue inhibitor of metalloproteinase-2 on alveolar macrophages of BALB/c mice exposed to short-term cigarette smoke.
Neoplasms
Increased expression of human macrophage metalloelastase (MMP-12) is associated with the invasion of endometrial adenocarcinoma.
Neoplasms
Induction and regulation of matrix metalloproteinase-12 in human airway smooth muscle cells.
Neoplasms
Induction of macrophage matrix metalloproteinase biosynthesis by surfactant protein D.
Neoplasms
Inflammation-related factors predicting prognosis of gastric cancer.
Neoplasms
Influence of Drugs Carried in Lipid Nanoparticles in Coronary Disease of Rabbit Transplanted Heart.
Neoplasms
Integrated expression analysis identifies transcription networks in mouse and human gastric neoplasia.
Neoplasms
Integrative miRNA and mRNA analysis in penile carcinomas reveals markers and pathways with potential clinical impact.
Neoplasms
Interleukin-6 involvement in brain arteriovenous malformations.
Neoplasms
Invasion and MMP expression profile in desmoid tumours.
Neoplasms
Involvement of specific matrix metalloproteinases during tumor necrosis factor/IFNgamma-based cancer therapy in mice.
Neoplasms
Knockdown of MMP12 inhibits the growth and invasion of lung adenocarcinoma cells.
Neoplasms
Knocking out matrix metalloproteinase 12 causes the accumulation of M2 macrophages in intestinal tumor microenvironment of mice.
Neoplasms
Macrophage elastase (matrix metalloproteinase-12) suppresses growth of lung metastases.
Neoplasms
Macrophage Elastase Induces TRAIL-mediated Tumor Cell Death Through its Carboxyterminal Domain.
Neoplasms
Macrophage metalloelastase degrades matrix and myelin proteins and processes a tumour necrosis factor-alpha fusion protein.
Neoplasms
Macrophage metalloelastase mediates acute cigarette smoke-induced inflammation via tumor necrosis factor-alpha release.
Neoplasms
Macrophage-derived metalloelastase is responsible for the generation of angiostatin in Lewis lung carcinoma.
Neoplasms
Macrophage-specific overexpression of human matrix metalloproteinase-12 in transgenic rabbits.
Neoplasms
Matrix metalloproteinase 12 expression is associated with tumor FOXP3+ regulatory T cell infiltration and poor prognosis in hepatocellular carcinoma.
Neoplasms
Matrix metalloproteinase 12 promotes tumor propagation in the lung.
Neoplasms
Matrix metalloproteinase-12 expression correlates with local recurrence and metastatic disease in non-small cell lung cancer patients.
Neoplasms
Matrix metalloproteinase-12 expression is increased in cutaneous melanoma and associated with tumor aggressiveness.
Neoplasms
Matrix metalloproteinase-12 is associated with overall survival in Chinese patients with gastric cancer.
Neoplasms
Mediators of glioblastoma resistance and invasion during antivascular endothelial growth factor therapy.
Neoplasms
Medulloblastoma displays distinct regional matrix metalloprotease expression.
Neoplasms
Melanoma cell therapy: Endothelial progenitor cells as shuttle of the MMP12 uPAR-degrading enzyme.
Neoplasms
Mesenchymal stem cells induce a fibrolytic phenotype by regulating mmu-miR-6769b-5p expression in macrophages.
Neoplasms
Metalloelastase (MMP-12) expression by tumour cells in squamous cell carcinoma of the vulva correlates with invasiveness, while that by macrophages predicts better outcome.
Neoplasms
Metalloelastase expression in a mouse macrophage cell line--regulation by 4beta-phorbol 12-myristate 13-acetate, lipopolysaccharide and dexamethasone.
Neoplasms
Methotrexate associated to lipid core nanoparticles improves cardiac allograft vasculopathy and the inflammatory profile in a rabbit heart graft model.
Neoplasms
Minocycline impedes African trypanosome invasion of the brain in a murine model.
Neoplasms
MMP-12 and S100s in saliva reflect different aspects of periodontal inflammation.
Neoplasms
Mouse macrophage metalloelastase gene delivery by HVJ-cationic liposomes in experimental antiangiogenic gene therapy for murine CT-26 colon cancer.
Neoplasms
Mouse macrophage metalloelastase gene transfer into a murine melanoma suppresses primary tumor growth by halting angiogenesis.
Neoplasms
Mouse macrophage metalloelastase generates angiostatin from plasminogen and suppresses tumor angiogenesis in murine colon cancer.
Neoplasms
mRNA expression of matrix metalloproteases and their inhibitors differs in subtypes of renal cell carcinomas.
Neoplasms
MTA2 silencing attenuates the metastatic potential of cervical cancer cells by inhibiting AP1-mediated MMP12 expression via the ASK1/MEK3/p38/YB1 axis.
Neoplasms
Murine TLR4 Is Implicated in Cigarette Smoke-Induced Pulmonary Inflammation.
Neoplasms
Myeloid-derived suppressor cells accumulate among myeloid cells contributing to tumor growth in matrix metalloproteinase 12 knockout mice.
Neoplasms
Optimizing the Diagnostic Role of Alpha-Fetoprotein and Abdominal Ultrasound by Adding Overexpressed Blood mRNA Matrix Metalloproteinase-12 for Diagnosis of HCV-Related Hepatocellular Carcinoma.
Neoplasms
Overexpression of matrix metalloproteinase-12 (MMP-12) correlates with poor prognosis of hepatocellular carcinoma.
Neoplasms
Possible involvements of nuclear factor-kappaB and activator protein-1 in the tumor necrosis factor-alpha-induced upregulation of matrix metalloproteinase-12 in human alveolar epithelial A549 cell line.
Neoplasms
Preventive and therapeutic effect of anti-IL-17 in an experimental model of elastase-induced lung injury in C57Bl6 mice.
Neoplasms
Prognostic values of matrix metalloproteinase family expression in human colorectal carcinoma.
Neoplasms
Recanalization of arterial thrombus, and inhibition with beta-radiation in a new murine carotid occlusion model: MRNA expression of angiopoietins, metalloproteinases, and their inhibitors.
Neoplasms
Reduction of protein kinase C delta attenuates tenascin-C stimulated glioma invasion in three-dimensional matrix.
Neoplasms
Regulation of matrix metalloproteinases: an overview.
Neoplasms
Role of Matrix Metallopeptidase 12 in the Development of Hepatocellular Carcinoma.
Neoplasms
Role of miR-647 in human gastric cancer suppression.
Neoplasms
Schwann Cell-Derived CCL2 Promotes the Perineural Invasion of Cervical Cancer.
Neoplasms
Selective MMP-12 inhibitors: WO-2008057254.
Neoplasms
Serotonin regulates macrophage-mediated angiogenesis in a mouse model of colon cancer allografts.
Neoplasms
Six cases of perforating pilomatricoma: Anetodermic changes with expression of matrix metalloproteinases.
Neoplasms
Systemic sclerosis-endothelial cell antiangiogenic pentraxin 3 and matrix metalloprotease 12 control human breast cancer tumor vascularization and development in mice.
Neoplasms
Systemic Th17-like cytokine pattern in gangrenous appendicitis but not in phlegmonous appendicitis.
Neoplasms
T-box transcription factor brachyury promotes tumor cell invasion and metastasis in non-small cell lung cancer via upregulation of matrix metalloproteinase 12.
Neoplasms
Targeting renal macrophage accumulation via c-fms kinase reduces tubular apoptosis but fails to modify progressive fibrosis in the obstructed rat kidney.
Neoplasms
Targeting ST2 expressing activated regulatory T cells in Kras-mutant lung cancer.
Neoplasms
Tenascin-C stimulates glioma cell invasion through matrix metalloproteinase-12.
Neoplasms
The association between MMP-12 82 A/G polymorphism and susceptibility to various malignant tumors: a meta-analysis.
Neoplasms
The overexpression and predictive significance of MMP-12 in esophageal squamous cell carcinoma.
Neoplasms
TNF?-activated mesenchymal stromal cells promote breast cancer metastasis by recruiting CXCR2(+) neutrophils.
Neoplasms
Transcriptomic and microRNA Expression Profiles Identify Biomarkers for Predicting Neo-Chemoradiotherapy Response in Esophageal Squamous Cell Carcinomas (ESCC).
Neoplasms
Transfection of mouse macrophage metalloelastase gene into murine CT-26 colon cancer cells suppresses orthotopic tumor growth, angiogenesis and vascular endothelial growth factor expression.
Neoplasms
Transforming growth factor-beta 1 inhibits cytokine-mediated induction of human metalloelastase in macrophages.
Neoplasms
Upregulation and differential expression of matrilysin (MMP-7) and metalloelastase (MMP-12) and their inhibitors TIMP-1 and TIMP-3 in Barrett's oesophageal adenocarcinoma.
Neoplasms
[Study on the expression of matrix metalloproteinase-12 and NM_002426 in squamous laryngeal carcinoma]
Neoplasms, Squamous Cell
Differential expression of matrilysin-1 (MMP-7), 92 kD gelatinase (MMP-9), and metalloelastase (MMP-12) in oral verrucous and squamous cell cancer.
Neoplasms, Squamous Cell
Metalloelastase (MMP-12) expression by tumour cells in squamous cell carcinoma of the vulva correlates with invasiveness, while that by macrophages predicts better outcome.
Nephritis
Macrophage metalloelastase as a major factor for glomerular injury in anti-glomerular basement membrane nephritis.
Nephritis, Hereditary
Role for macrophage metalloelastase in glomerular basement membrane damage associated with alport syndrome.
Nephrotic Syndrome
Expression of macrophage metalloelastase (MMP-12) in podocytes of hereditary nephrotic mice (ICGN strain).
Neuralgia
Locating the Site of Neuropathic Pain In Vivo Using MMP-12-Targeted Magnetic Nanoparticles.
Neuroinflammatory Diseases
Locating the Site of Neuropathic Pain In Vivo Using MMP-12-Targeted Magnetic Nanoparticles.
Neuroinflammatory Diseases
Matrix metalloproteinase-12 contributes to neuroinflammation in the aged brain.
Obesity
Identification of matrix metalloproteinase-12 as a candidate molecule for prevention and treatment of cardiometabolic disease.
Obesity
Matrix metalloproteinase 12 modulates high-fat-diet induced glomerular fibrogenesis and inflammation in a mouse model of obesity.
Obesity
Matrix metalloproteinases are differentially expressed in adipose tissue during obesity and modulate adipocyte differentiation.
Obesity
MMP-12 as a potential biomarker to forecast ischemic stroke in obese patients.
Obesity
Obesity-induced remodeling of the adipose tissue elastin network is independent of the metalloelastase MMP-12.
Obesity
Role of MMP-1 (-519A/G, -1607 1G/2G), MMP-3 (Lys45Glu), MMP-7 (-181A/G), and MMP-12 (-82A/G) Variants and Plasma MMP Levels on Obesity-Related Phenotypes and Microvascular Reactivity in a Tunisian Population.
Obesity
Tissue-specific differences in inflammatory infiltrate and matrix metalloproteinase expression in adipose tissue and liver of mice with diet-induced obesity.
Oral Submucous Fibrosis
Estimation of salivary matrix metalloproteinases- 12 (MMP- 12) levels among patients presenting with oral submucous fibrosis and oral squamous cell carcinoma.
Osteoarthritis
Association of increased expression of macrophage elastase (matrix metalloproteinase 12) with rheumatoid arthritis.
Osteoarthritis
Macrophage-specific metalloelastase (MMP-12) immunoexpression in the osteochondral unit in osteoarthritis correlates with BMI and disease severity.
Osteoarthritis
Selective MMP-12 inhibitors: WO-2008057254.
Osteosarcoma
Human macrophage metalloelastase (MMP-12) expression is induced in chondrocytes during fetal development and malignant transformation.
Ovarian Neoplasms
Association between matrix metalloproteinases polymorphisms and ovarian cancer risk: A meta-analysis and systematic review.
Ovarian Neoplasms
The prognostic values of matrix metalloproteinases in ovarian cancer.
Pancreatic Neoplasms
Human macrophage metalloelastase worsens the prognosis of pancreatic cancer.
Pancreatic Neoplasms
Prognostic impact of a compartment-specific angiogenic marker profile in patients with pancreatic cancer.
Papillomavirus Infections
Co-expression of metalloproteinases 11 and 12 in cervical scrapes cells from cervical precursor lesions.
Periodontitis
Association of Common Variants in MMPs with Periodontitis Risk.
Periodontitis
Microarray and quantitative RT-PCR analyses in calcium-channel blockers induced gingival overgrowth tissues of periodontitis patients.
Peritonitis
C-terminal truncation of IFN-? inhibits proinflammatory macrophage responses and is deficient in autoimmune disease.
Peritonitis
Macrophage matrix metalloproteinase-12 dampens inflammation and neutrophil influx in arthritis.
Pityriasis Lichenoides
Enhanced expression of human metalloelastase (MMP-12) in cutaneous granulomas and macrophage migration.
Pneumococcal Infections
Pneumococcal Infection Aggravates Elastase-Induced Emphysema via Matrix Metalloproteinase 12 Overexpression.
Pneumonia
Discovery of potent and selective matrix metalloprotease 12 inhibitors for the potential treatment of chronic obstructive pulmonary disease (COPD).
Pneumonia
Eosinophil-derived IL-13 Promotes Emphysema.
Pneumonia
Extracellular matrix remodeling genes polymorphisms and risk of chronic bronchitis and recurrent pneumonia in children.
Pneumonia
Lack of Transcription Factor p53 Exacerbates Elastase-Induced Emphysema in Mice.
Pneumonia
Membrane-bound FRET probe visualizes MMP12 activity in pulmonary inflammation.
Pneumonia
Murine TLR4 Is Implicated in Cigarette Smoke-Induced Pulmonary Inflammation.
Pneumonia
Pathogenic role of matrix metalloproteases and their inhibitors in asthma and chronic obstructive pulmonary disease and therapeutic relevance of matrix metalloproteases inhibitors.
Pneumonia
Pathophysiological changes induced by Pseudomonas aeruginosa infection are involved in MMP-12 and MMP-13 upregulation in human carcinoma epithelial cells and a pneumonia mouse model.
Pneumonia
Quercetin prevents progression of disease in elastase/LPS-exposed mice by negatively regulating MMP expression.
Pneumonia
Role of recently migrated monocytes in cigarette smoke-induced lung inflammation in different strain of mice.
Pneumonia
Sequential targeted deficiency of SP-A and -D leads to progressive alveolar lipoproteinosis and emphysema.
Pneumonia
The selective MMP-12 inhibitor, AS111793 reduces airway inflammation in mice exposed to cigarette smoke.
Pneumonia
Therapeutic Targeting of MMP-12 for the Treatment of Chronic Obstructive Pulmonary Disease.
Pneumonia
Type III Secretion System of Pseudomonas aeruginosa Affects Matrix Metalloproteinase 12 (MMP-12) and MMP-13 Expression via Nuclear Factor ?B Signaling in Human Carcinoma Epithelial Cells and a Pneumonia Mouse Model.
Polycythemia
Increased Pulmonary GM-CSF Causes Alveolar Macrophage Accumulation: Mechanistic Implications for Desquamative Interstitial Pneumonitis.
Pre-Eclampsia
Maternal Immune System and State of Inflammation Dictate the Fate and Severity of Disease in Preeclampsia.
Pre-Eclampsia
Matrix metalloproteinase multiplex screening identifies increased MMP-2 urine concentrations in women predicted to develop preeclampsia.
Prostatic Neoplasms
Bone marrow stromal cells enhance prostate cancer cell invasion through type I collagen in an MMP-12 dependent manner.
Prostatic Neoplasms
Expression and functional role of CCR9 in prostate cancer cell migration and invasion.
Prostatic Neoplasms
Overexpression of the nucleoporin Nup88 stimulates migration and invasion of HeLa cells.
Proteinuria
Spleen tyrosine kinase promotes acute neutrophil-mediated glomerular injury via activation of JNK and p38 MAPK in rat nephrotoxic serum nephritis.
Pseudomonas Infections
Pathophysiological changes induced by Pseudomonas aeruginosa infection are involved in MMP-12 and MMP-13 upregulation in human carcinoma epithelial cells and a pneumonia mouse model.
Pseudoxanthoma Elasticum
Enhanced expression of human metalloelastase (MMP-12) in cutaneous granulomas and macrophage migration.
Psoriasis
Differences in Osteoimmunological Biomarkers Predictive of Psoriatic Arthritis among a Large Italian Cohort of Psoriatic Patients.
Psoriasis
Distinct molecular signatures of mild extrinsic and intrinsic atopic dermatitis.
Psoriasis
Influence of narrowband ultraviolet-B phototherapy on plasma concentration of matrix metalloproteinase-12 in psoriatic patients.
Psoriasis
Metalloelastase (MMP-12) and 92-kDa gelatinase (MMP-9) as well as their inhibitors, TIMP-1 and -3, are expressed in psoriatic lesions.
Psoriasis
ROC analysis of selected matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) in psoriatic patients.
Psoriasis
[Expression of genes for metalloproteinases (MMP-1, MMP-2, MMP-9, and MMP-12) associated with psoriasis].
Pulmonary Disease, Chronic Obstructive
A large lung gene expression study identifying IL1B as a novel player in airway inflammation in COPD airway epithelial cells.
Pulmonary Disease, Chronic Obstructive
A mathematical model of protease-antiprotease homeostasis failure in chronic obstructive pulmonary disease (COPD).
Pulmonary Disease, Chronic Obstructive
A QSAR study on the inhibition mechanism of matrix metalloproteinase-12 by arylsulfone analogs based on molecular orbital calculations.
Pulmonary Disease, Chronic Obstructive
A selective matrix metalloprotease 12 inhibitor for potential treatment of chronic obstructive pulmonary disease (COPD): discovery of (S)-2-(8-(methoxycarbonylamino)dibenzo[b,d]furan-3-sulfonamido)-3-methylbutanoic acid (MMP408).
Pulmonary Disease, Chronic Obstructive
Association of matrix metalloproteinase-12 polymorphisms with chronic obstructive pulmonary disease risk: A protocol for systematic review and meta analysis.
Pulmonary Disease, Chronic Obstructive
Biomarkers of oxidative stress and protein-protein interaction in chronic obstructive pulmonary disease.
Pulmonary Disease, Chronic Obstructive
Characterization of peptide fragments from lung elastin degradation in chronic obstructive pulmonary disease.
Pulmonary Disease, Chronic Obstructive
Cigarette smoke-induced hypercapnic emphysema in C3H mice is associated with increases of macrophage metalloelastase and substance P in the lungs.
Pulmonary Disease, Chronic Obstructive
Comparative Study of Cytokine Levels in Different Respiratory Samples in Mild-to-Moderate AECOPD Patients.
Pulmonary Disease, Chronic Obstructive
Crystal structures of novel non-peptidic, non-zinc chelating inhibitors bound to MMP-12.
Pulmonary Disease, Chronic Obstructive
Design, (Radio)Synthesis, and in Vitro and in Vivo Evaluation of Highly Selective and Potent Matrix Metalloproteinase 12 (MMP-12) Inhibitors as Radiotracers for Positron Emission Tomography.
Pulmonary Disease, Chronic Obstructive
Design, synthesis, biological evaluation, and NMR studies of a new series of arylsulfones as selective and potent matrix metalloproteinase-12 inhibitors.
Pulmonary Disease, Chronic Obstructive
Development of matrix metalloproteinase-targeted probes for lung inflammation detection with positron emission tomography.
Pulmonary Disease, Chronic Obstructive
Discovery of potent and selective matrix metalloprotease 12 inhibitors for the potential treatment of chronic obstructive pulmonary disease (COPD).
Pulmonary Disease, Chronic Obstructive
Effect of an MMP-9/MMP-12 inhibitor on smoke-induced emphysema and airway remodelling in guinea pigs.
Pulmonary Disease, Chronic Obstructive
Effect of World Trade Center Dust Exposure and Chronic Intermittent Hypoxia on Macrophage Matrix Metalloproteinase-12 Expression in Mice.
Pulmonary Disease, Chronic Obstructive
Effects of an oral MMP-9 and -12 inhibitor, AZD1236, on biomarkers in moderate/severe COPD: A randomised controlled trial.
Pulmonary Disease, Chronic Obstructive
Elevated MMP-12 protein levels in induced sputum from patients with COPD.
Pulmonary Disease, Chronic Obstructive
Exome-wide analysis of rare coding variation identifies novel associations with COPD and airflow limitation in MOCS3, IFIT3 and SERPINA12.
Pulmonary Disease, Chronic Obstructive
Experimental Pneumocystis lung infection promotes M2a alveolar macrophage-derived MMP12 production.
Pulmonary Disease, Chronic Obstructive
Expressions of MMP-12, TIMP-4, and Neutrophil Elastase in PBMCs and Exhaled Breath Condensate in Patients with COPD and Their Relationships with Disease Severity and Acute Exacerbations.
Pulmonary Disease, Chronic Obstructive
Fine particulate matter exposure promotes M2 macrophage polarization through inhibiting histone deacetylase 2 in the pathogenesis of chronic obstructive pulmonary disease.
Pulmonary Disease, Chronic Obstructive
Functional Studies of Single-Nucleotide Polymorphisms Suggest Heterogeneity in Chronic Obstructive Pulmonary Disease due to Susceptibility of Different Cell Types.
Pulmonary Disease, Chronic Obstructive
Gene expression profiling in lung tissues from mice exposed to cigarette smoke, lipopolysaccharide, or smoke plus lipopolysaccharide by inhalation.
Pulmonary Disease, Chronic Obstructive
Gene-Gene Interactions Between Glutathione S-Transferase M1 and Matrix Metalloproteinases 1, 9, and 12 in Chronic Obstructive Pulmonary Disease in Serbians.
Pulmonary Disease, Chronic Obstructive
Genetic Polymorphism of Matrix Metalloproteinase Family and Chronic Obstructive Pulmonary Disease Susceptibility: a Meta-analysis.
Pulmonary Disease, Chronic Obstructive
Genetic polymorphisms of matrix metalloproteinases and protein levels in chronic obstructive pulmonary disease in a Mexican population.
Pulmonary Disease, Chronic Obstructive
Genetic polymorphisms of matrix metalloproteinases: functional importance in the development of chronic obstructive pulmonary disease?
Pulmonary Disease, Chronic Obstructive
Genetics of COPD.
Pulmonary Disease, Chronic Obstructive
Increase in macrophage elastase (MMP-12) in lungs from patients with chronic obstructive pulmonary disease.
Pulmonary Disease, Chronic Obstructive
Increased chemokines levels in patients with chronic obstructive pulmonary disease: correlation with quantitative computed tomography metrics.
Pulmonary Disease, Chronic Obstructive
Increased Cytokine Response of Rhinovirus-infected Airway Epithelial Cells in Chronic Obstructive Pulmonary Disease.
Pulmonary Disease, Chronic Obstructive
Increased levels of inflammatory biomarker CX3CL1 in patients with chronic obstructive pulmonary disease.
Pulmonary Disease, Chronic Obstructive
Induction and regulation of matrix metalloproteinase-12 in human airway smooth muscle cells.
Pulmonary Disease, Chronic Obstructive
Inflammatory mediators in exhaled breath condensate and peripheral blood of healthy donors and stable COPD patients.
Pulmonary Disease, Chronic Obstructive
Is MMP-7 Gene Polymorphism a Possible Risk Factor for Chronic Obstructive Pulmonary Disease in Turkish Patients.
Pulmonary Disease, Chronic Obstructive
Macrophage elastase (MMP-12): a pro-inflammatory mediator?
Pulmonary Disease, Chronic Obstructive
Macrophage metalloelastase (MMP-12) as a target for inflammatory respiratory diseases.
Pulmonary Disease, Chronic Obstructive
Matrix metalloproteinase 12 overexpression in lung epithelial cells plays a key role in emphysema to lung bronchioalveolar adenocarcinoma transition.
Pulmonary Disease, Chronic Obstructive
Matrix metalloproteinase 12 silencing: A therapeutic approach to treat pathological lung tissue remodeling?
Pulmonary Disease, Chronic Obstructive
Matrix metalloproteinase 12, asthma, and COPD.
Pulmonary Disease, Chronic Obstructive
Matrix metalloproteinase gene polymorphisms: lack of association with chronic obstructive pulmonary disease in a Brazilian population.
Pulmonary Disease, Chronic Obstructive
Matrix metalloproteinase-12 (MMP-12) SNP affects MMP activity, lung macrophage infiltration and protects against emphysema in COPD.
Pulmonary Disease, Chronic Obstructive
Matrix metalloproteinase-12 is a therapeutic target for asthma in children and young adults.
Pulmonary Disease, Chronic Obstructive
Matrix metalloproteinases in the pathogenesis of asthma and COPD: implications for therapy.
Pulmonary Disease, Chronic Obstructive
Metalloelastase (MMP-12) induced inflammatory response in mice airways: effects of dexamethasone, rolipram and marimastat.
Pulmonary Disease, Chronic Obstructive
MMP-12 activates protease-activated receptor-1, upregulates placenta growth factor, and leads to pulmonary emphysema.
Pulmonary Disease, Chronic Obstructive
MMP-12, a Promising Therapeutic Target for Neurological Diseases.
Pulmonary Disease, Chronic Obstructive
MMP-3 (-1171 5A/6A; Lys45Glu) variants affect serum levels of matrix metalloproteinase (MMP)-3 and correlate with severity of COPD: A study of MMP-3, MMP-7 and MMP-12 in a Tunisian population.
Pulmonary Disease, Chronic Obstructive
MMP12, lung function, and COPD in high-risk populations.
Pulmonary Disease, Chronic Obstructive
Neutrophil elastase inhibitors.
Pulmonary Disease, Chronic Obstructive
New insights into the substrate specificity of macrophage elastase MMP-12.
Pulmonary Disease, Chronic Obstructive
NMR and bioinformatics discovery of exosites that tune metalloelastase specificity for solubilized elastin and collagen triple helices.
Pulmonary Disease, Chronic Obstructive
Non-small cell lung cancer is characterised by a distinct inflammatory signature in serum compared with chronic obstructive pulmonary disease.
Pulmonary Disease, Chronic Obstructive
Novel strategy to identify genetic risk factors for COPD severity: a genetic isolate.
Pulmonary Disease, Chronic Obstructive
Pathogenesis of cigarette smoke-induced chronic obstructive pulmonary disease and therapeutic effects of glucocorticoids and N-acetylcysteine in rats.
Pulmonary Disease, Chronic Obstructive
Pathogenic role of matrix metalloproteases and their inhibitors in asthma and chronic obstructive pulmonary disease and therapeutic relevance of matrix metalloproteases inhibitors.
Pulmonary Disease, Chronic Obstructive
Patterns of airway inflammation and MMP-12 expression in smokers and ex-smokers with COPD.
Pulmonary Disease, Chronic Obstructive
Pneumococcal Infection Aggravates Elastase-Induced Emphysema via Matrix Metalloproteinase 12 Overexpression.
Pulmonary Disease, Chronic Obstructive
Polymorphisms in Matrix Metalloproteinase-1, -9 and -12 Genes and the Risk of Chronic Obstructive Pulmonary Disease in a Korean Population.
Pulmonary Disease, Chronic Obstructive
Relationship between plasma matrix metalloproteinase levels, pulmonary function, bronchodilator response, and emphysema severity.
Pulmonary Disease, Chronic Obstructive
Relationships of COX2 and MMP12 genetic polymorphisms with chronic obstructive pulmonary disease risk: a meta-analysis.
Pulmonary Disease, Chronic Obstructive
Retraction Note to: Relationships of COX2 and MMP12 genetic polymorphisms with chronic obstructive pulmonary disease risk: a meta-analysis.
Pulmonary Disease, Chronic Obstructive
Revisiting matrix metalloproteinase 12: its role in pathophysiology of asthma and related pulmonary diseases.
Pulmonary Disease, Chronic Obstructive
Role of matrix metalloproteinases in the development of airway inflammation and remodeling.
Pulmonary Disease, Chronic Obstructive
Safety and tolerability of an oral MMP-9 and -12 inhibitor, AZD1236, in patients with moderate-to-severe COPD: A randomised controlled 6-week trial.
Pulmonary Disease, Chronic Obstructive
Severity of chronic obstructive pulmonary disease with 'exacerbator with emphysema phenotype' is associated with potential biomarkers.
Pulmonary Disease, Chronic Obstructive
Sputum matrix metalloproteinase-12 in patients with chronic obstructive pulmonary disease and asthma: Relationship to disease severity.
Pulmonary Disease, Chronic Obstructive
Synthesis of radioiodinated probes targeted toward matrix metalloproteinase-12.
Pulmonary Disease, Chronic Obstructive
The G allele of MMP12 -82 A?>?G promoter polymorphism as a protective factor for COPD in Bulgarian population.
Pulmonary Disease, Chronic Obstructive
The role of MMP-12 gene polymorphism?-?82 A-to-G (rs2276109) in immunopathology of COPD in polish patients: a case control study.
Pulmonary Disease, Chronic Obstructive
The selective MMP-12 inhibitor, AS111793 reduces airway inflammation in mice exposed to cigarette smoke.
Pulmonary Disease, Chronic Obstructive
Therapeutic Targeting of MMP-12 for the Treatment of Chronic Obstructive Pulmonary Disease.
Pulmonary Disease, Chronic Obstructive
[Association of the MMP3, MMP9, ADAM33 and TIMP3 genes polymorphic markers with development and progression of chronic obstructive pulmonary disease].
Pulmonary Disease, Chronic Obstructive
[Influence of N-acetylcysteine on the cytokines and matrix metalloproteinases in chronic obstructive pulmonary disease rat models]
Pulmonary Disease, Chronic Obstructive
[Polymorphism in promoter regions of matrix metalloproteinases (MMP1, MMP9, and MMP12) in chronic obstructive pulmonary disease patients]
Pulmonary Disease, Chronic Obstructive
[Study on matrix metalloproteinase 1, 9, 12 polymorphisms and susceptibility to chronic obstructive pulmonary disease among Han nationality in northern China]
Pulmonary Emphysema
Cigarette Smoke-Induced Pulmonary Inflammation and Emphysema Are Attenuated in CCR6-Deficient Mice.
Pulmonary Emphysema
Loss of integrin alpha(v)beta6-mediated TGF-beta activation causes Mmp12-dependent emphysema.
Pulmonary Emphysema
Matrix metalloproteinases and TIMPs: properties and implications for the treatment of chronic obstructive pulmonary disease.
Pulmonary Emphysema
Measurement of metalloproteinases.
Pulmonary Emphysema
MMP-12 activates protease-activated receptor-1, upregulates placenta growth factor, and leads to pulmonary emphysema.
Pulmonary Emphysema
Selective MMP-12 inhibitors: WO-2008057254.
Pulmonary Fibrosis
Association of a functional polymorphism in the matrix metalloproteinase-12 promoter region with systemic sclerosis in an Italian population.
Pulmonary Fibrosis
Effect of World Trade Center Dust Exposure and Chronic Intermittent Hypoxia on Macrophage Matrix Metalloproteinase-12 Expression in Mice.
Pulmonary Fibrosis
Essential role of MMP-12 in Fas-induced lung fibrosis.
Pulmonary Fibrosis
Increased serum levels and tissue expression of matrix metalloproteinase-12 in patients with systemic sclerosis: correlation with severity of skin and pulmonary fibrosis and vascular damage.
Pulmonary Fibrosis
Indole alkaloids from leaves of Alstonia scholaris (L.) R. Br. protect against emphysema in mice.
Pulmonary Fibrosis
Induction and regulation of macrophage metalloelastase by hyaluronan fragments in mouse macrophages.
Pulmonary Fibrosis
Macrophage elastase (MMP-12): a pro-inflammatory mediator?
Pulmonary Fibrosis
Macrophage metalloelastase (MMP-12) deficiency does not alter bleomycin-induced pulmonary fibrosis in mice.
Pulmonary Fibrosis
Matrix metalloproteinase-12 (MMP-12) deficiency attenuates experimental crescentic anti-GBM glomerulonephritis.
Pulmonary Fibrosis
Revisiting matrix metalloproteinase 12: its role in pathophysiology of asthma and related pulmonary diseases.
Pulmonary Fibrosis
Transforming growth factor (TGF)-beta1 stimulates pulmonary fibrosis and inflammation via a Bax-dependent, bid-activated pathway that involves matrix metalloproteinase-12.
Renal Insufficiency, Chronic
The association between plasma proteomics and incident cardiovascular disease identifies MMP-12 as a promising cardiovascular risk marker in patients with chronic kidney disease.
Respiratory Insufficiency
Overlapping and enzyme-specific contributions of matrix metalloproteinases-9 and -12 in IL-13-induced inflammation and remodeling.
Respiratory Syncytial Virus Infections
Pulmonary C Fibers Modulate MMP-12 Production via PAR2 and Are Involved in the Long-Term Airway Inflammation and Airway Hyperresponsiveness Induced by Respiratory Syncytial Virus Infection.
Retinal Detachment
Retinal MMP-12, MMP-13, TIMP-1, and TIMP-2 Expression in Murine Experimental Retinal Detachment.
Retinal Neovascularization
Macrophage metalloelastase (MMP-12) deficiency mitigates retinal inflammation and pathological angiogenesis in ischemic retinopathy.
Rheumatoid Nodule
MMP expression in rheumatoid inflammation: the rs11568818 polymorphism is associated with MMP-7 expression at an extra-articular site.
Sarcoidosis
Enhanced expression of human metalloelastase (MMP-12) in cutaneous granulomas and macrophage migration.
Sarcoidosis
Gene expression profiling identifies MMP-12 and ADAMDEC1 as potential pathogenic mediators of pulmonary sarcoidosis.
Sarcoidosis
Matrix Metalloproteinase-12 Is Required for Granuloma Progression.
Sarcoidosis, Pulmonary
Gene expression profiling identifies MMP-12 and ADAMDEC1 as potential pathogenic mediators of pulmonary sarcoidosis.
Sarcoidosis, Pulmonary
Matrix Metalloproteinase-12 Is Required for Granuloma Progression.
Scleroderma, Systemic
Association of a functional polymorphism in the matrix metalloproteinase-12 promoter region with systemic sclerosis in an Italian population.
Scleroderma, Systemic
Increased serum levels and tissue expression of matrix metalloproteinase-12 in patients with systemic sclerosis: correlation with severity of skin and pulmonary fibrosis and vascular damage.
Scleroderma, Systemic
MMP-12 deficiency attenuates angiotensin II-induced vascular injury, M2 macrophage accumulation, and skin and heart fibrosis.
Scleroderma, Systemic
Modulation of the angiogenic phenotype of normal and systemic sclerosis endothelial cells by gain-loss of function of pentraxin 3 and matrix metalloproteinase 12.
Seizures
A Hydroxypyrone-Based Inhibitor of Metalloproteinase-12 Displays Neuroprotective Properties in Both Status Epilepticus and Optic Nerve Crush Animal Models.
Silicosis
[Screen and validation of differentially expressing genes related to silicotic pulmonary fibrosis in rats].
Skin Diseases
Enhanced expression of human metalloelastase (MMP-12) in cutaneous granulomas and macrophage migration.
Skin Neoplasms
Expression of human macrophage metalloelastase (MMP-12) by tumor cells in skin cancer.
Skin Neoplasms
Metalloelastase (MMP-12) expression by tumour cells in squamous cell carcinoma of the vulva correlates with invasiveness, while that by macrophages predicts better outcome.
Sleep Apnea, Obstructive
Effect of World Trade Center Dust Exposure and Chronic Intermittent Hypoxia on Macrophage Matrix Metalloproteinase-12 Expression in Mice.
Spinal Cord Compression
An adverse role for matrix metalloproteinase 12 after spinal cord injury in mice.
Spinal Cord Injuries
An adverse role for matrix metalloproteinase 12 after spinal cord injury in mice.
Spinal Cord Injuries
Expression of MMP-12 after neonatal hypoxic-ischemic brain injury in mice.
Spinal Cord Injuries
MMP-12, a Promising Therapeutic Target for Neurological Diseases.
Squamous Cell Carcinoma of Head and Neck
Estimation of salivary matrix metalloproteinases- 12 (MMP- 12) levels among patients presenting with oral submucous fibrosis and oral squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Expression of matrix metalloproteinase-12 is correlated with extracapsular spread of tumor from nodes with metastasis in head and neck squamous cell carcinoma.
ST Elevation Myocardial Infarction
Expression of matrix metalloproteinases-12 in ST-segment elevation myocardial infarction: A case-control study.
Staphylococcal Infections
Transcriptomic analysis identifies upregulation of secreted phosphoprotein 1 in silicotic rats.
Status Epilepticus
A Hydroxypyrone-Based Inhibitor of Metalloproteinase-12 Displays Neuroprotective Properties in Both Status Epilepticus and Optic Nerve Crush Animal Models.
Stomach Neoplasms
Human macrophage metalloelastase expression in gastric cancer and its relationship with gastric cancer prognosis.
Stomach Neoplasms
Identification of novel molecular markers for detection of gastric cancer cells in the peripheral blood circulation using genome-wide microarray analysis.
Stomach Neoplasms
Matrix metalloproteinase gene expressions might be oxidative stress targets in gastric cancer cell lines.
Stomach Neoplasms
Matrix metalloproteinase-12 is associated with overall survival in Chinese patients with gastric cancer.
Stomach Neoplasms
S100A8 and S100A9 promotes invasion and migration through p38 mitogen-activated protein kinase-dependent NF-?B activation in gastric cancer cells.
Stomach Neoplasms
[The expression of human macrophage metalloelastase mRNA in gastric cancer cell lines and tissues and its clinical significance]
Stomach Ulcer
[Role of Allelic Genes of Matrix Metalloproteinases and Their Tissue Inhibitors in the Peptic Ulcer Disease Development].
Stroke
A novel MMP12 locus is associated with large artery atherosclerotic stroke using a genome-wide age-at-onset informed approach.
Stroke
Differences in matrix metalloproteinase-1 and matrix metalloproteinase-12 transcript levels among carotid atherosclerotic plaques with different histopathological characteristics.
Stroke
Integrative studies implicate matrix metalloproteinase-12 as a culprit gene for large-artery atherosclerotic stroke.
Stroke
Matrix metalloproteinase (MMP)-12 expression has a negative impact on sensorimotor function following intracerebral haemorrhage in mice.
Stroke
MMP-12, a Promising Therapeutic Target for Neurological Diseases.
Stroke
Plasma Matrix Metalloproteinases in Patients With Stroke During Intensive Rehabilitation Therapy.
Subarachnoid Hemorrhage
Polymorphisms in matrix metalloproteinase-1, -3, -9, and -12 genes in relation to subarachnoid hemorrhage.
Synovitis
Overexpression of human matrix metalloproteinase-12 enhances the development of inflammatory arthritis in transgenic rabbits.
Tenosynovitis
Imbalanced MMP-3 and MMP-12 serum levels in systemic lupus erythematosus patients with Jaccoud's arthropathy and a distinctive MRI pattern.
Thrombosis
Expression changes and roles of matrix metalloproteinases in a rat model of traumatic deep vein thrombosis.
Thrombosis
Expression of matrix metalloproteinases-12 in ST-segment elevation myocardial infarction: A case-control study.
Thrombosis
Spleen tyrosine kinase promotes acute neutrophil-mediated glomerular injury via activation of JNK and p38 MAPK in rat nephrotoxic serum nephritis.
Thrombosis
Synergistic Expression of Histone Deacetylase 9 and Matrix Metalloproteinase 12 in M4 Macrophages in Advanced Carotid Plaques.
Toxoplasmosis
Elevated concentrations of matrix metalloproteinase-12 and elastin degradation products in the sera of pregnant women infected with Toxoplasma gondii.
Triple Negative Breast Neoplasms
Whole transcriptome profiling of patient-derived xenograft models as a tool to identify both tumor and stromal specific biomarkers.
Urinary Bladder Neoplasms
Genetic polymorphisms in matrix metalloproteinases (MMPs) and tissue inhibitors of MPs (TIMPs), and bladder cancer susceptibility.
Urinary Bladder Neoplasms
Matrix metalloproteinase polymorphisms and bladder cancer risk.
Urinary Bladder Neoplasms
Matrix metalloproteinase polymorphisms are associated with bladder cancer invasiveness.
Uterine Cervical Neoplasms
MTA2 silencing attenuates the metastatic potential of cervical cancer cells by inhibiting AP1-mediated MMP12 expression via the ASK1/MEK3/p38/YB1 axis.
Uterine Cervical Neoplasms
Overexpression of the nucleoporin Nup88 stimulates migration and invasion of HeLa cells.
Uterine Cervical Neoplasms
[The utility of metalloproteinases (MMPs) and their inhibitors (TIMPs) in diagnostics of gynecological malignancies].
Varicose Veins
Morphologic characteristics of varicose veins: possible role of metalloproteinases.
Vascular System Injuries
Matrix metalloproteinase-12 is an essential mediator of acute and chronic arterial stiffening.
Vascular System Injuries
MMP-12 deficiency attenuates angiotensin II-induced vascular injury, M2 macrophage accumulation, and skin and heart fibrosis.
Vascular System Injuries
Role of the fibrinolytic and matrix metalloproteinase systems in arterial neointima formation after vascular injury.
Virus Diseases
Increased Cytokine Response of Rhinovirus-infected Airway Epithelial Cells in Chronic Obstructive Pulmonary Disease.
Virus Diseases
Pulmonary C Fibers Modulate MMP-12 Production via PAR2 and Are Involved in the Long-Term Airway Inflammation and Airway Hyperresponsiveness Induced by Respiratory Syncytial Virus Infection.
Virus Diseases
Role of Matrix Metallopeptidase 12 in the Development of Hepatocellular Carcinoma.
Vitamin D Deficiency
Airway infection with Nontypeable Haemophilus influenzae is more rapidly eradicated in vitamin D deficient mice.
Whooping Cough
Alpha1-antitrypsin suppresses TNF-alpha and MMP-12 production by cigarette smoke-stimulated macrophages.
Whooping Cough
Proteinase-activated receptor-1 regulation of macrophage elastase (MMP-12) secretion by serine proteinases.
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3.4.24.65 macrophage elastase
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The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable). 
