Reference on EC 3.4.24.59 - mitochondrial intermediate peptidase
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Isaya, G.; Kalousek, F.; Rosenberg, L.E.
Amino-terminal octapeptides function as recognition signals for the mitochondrial intermediate peptidase
J. Biol. Chem.
267
7904-7910
1992
BRENDA: Rattus norvegicus
Textmining: Neurospora, Homo sapiens, Rattus
Isaya, G.; Kalousek, F.; Rosenberg, L.E.
Sequence analysis of rat mitochondrial intermediate peptidase: similarity to zinc metallopeptidases and to a putative yeast homologue
Proc. Natl. Acad. Sci. USA
89
8317-8321
1992
BRENDA: Rattus norvegicus
Textmining: Saccharomyces cerevisiae, Rattus, other sequences
Isaya, G.; Miklos, D.; Rollins, R.A.
MIP1, a new yeast gene homologous to the rat mitochondrial intermediate peptidase gene, is required for oxidative metabolism in Saccharomyces cerevisiae
Mol. Cell. Biol.
14
5603-5616
1994
BRENDA: Saccharomyces cerevisiae
Textmining: Rattus, Homo sapiens
Isaya, G.; Kalousek, F.
Mitochondrial intermediate peptidase
Methods Enzymol.
248
556-567
1995
Rattus norvegicus
Kalousek, F.; Isaya, G.; Rosenberg, L.E.
Rat liver mitochondrial intermediate peptidase (MIP): purification and initial characterization
EMBO J.
11
2803-2809
1992
BRENDA: Rattus norvegicus
Textmining: Rattus
Branda, S.S.; Isaya, G.
Prediction and identification of new natural substrates of the yeast mitochondrial intermediate peptidase
J. Biol. Chem.
270
27366-27373
1995
BRENDA: Saccharomyces cerevisiae
Textmining: Electron
Isaya, G.
Mitochondrial intermediate peptidase
Handbook Of Proteolytic Enzymes(Barrett,A. J. ,Rawlings,N. D. ,Woessner,J. F. ,Eds. )Academic Press
1
366-369
2004
Saccharomyces cerevisiae, Homo sapiens, Mus musculus, Rattus norvegicus, Schizophyllum commune
-
Hervouet, E.; Pecina, P.; Demont, J.; Vojtiskova, A.; Simonnet, H.; Houstek, J.; Godinot, C.
Inhibition of cytochrome c oxidase subunit 4 precursor processing by the hypoxia mimic cobalt chloride
Biochem. Biophys. Res. Commun.
344
1086-1093
2006
BRENDA: Homo sapiens
Textmining: Saccharomyces cerevisiae
van der Nest, M.A.; Slippers, B.; Stenlid, J.; Wilken, P.M.; Vasaitis, R.; Wingfield, M.J.; Wingfield, B.D.
Characterization of the systems governing sexual and self-recognition in the white rot homobasidiomycete Amylostereum areolatum
Curr. Genet.
53
323-336
2008
BRENDA: Amylostereum areolatum
Textmining: Coprinopsis cinerea, Schizophyllum commune
Marcondes, M.; Torquato, R.; Assis, D.; Juliano, M.; Hayashi, M.; Oliveira, V.
Mitochondrial intermediate peptidase: Expression in Escherichia coli and improvement of its enzymatic activity detection with FRET substrates
Biochem. Biophys. Res. Commun.
391
123-128
2010
BRENDA: Homo sapiens
Textmining: Escherichia coli, Escherichia coli BL21 (DE3) pLysS
Lee, S.F.; Srinivasan, B.; Sephton, C.F.; Dries, D.R.; Wang, B.; Yu, C.; Wang, Y.; Dewey, C.M.; Shah, S.; Jiang, J.; Yu, G.
Gamma-secretase-regulated proteolysis of the Notch receptor by mitochondrial intermediate peptidase
J. Biol. Chem.
286
27447-27453
2011
Homo sapiens
Voegtle, F.N.; Prinz, C.; Kellermann, J.; Lottspeich, F.; Pfanner, N.; Meisinger, C.
Mitochondrial protein turnover: role of the precursor intermediate peptidase Oct1 in protein stabilization
Mol. Biol. Cell
22
2135-2143
2011
Saccharomyces cerevisiae
Teixeira, P.; Glaser, E.
Processing peptidases in mitochondria and chloroplasts
Biochim. Biophys. Acta
1833
360-370
2013
Rattus norvegicus
Marcondes, M.; Alves, F.; Assis, D.; Hirata, I.; Juliano, L.; Oliveira, V.; Juliano, M.
Substrate specificity of mitochondrial intermediate peptidase analysed by a support-bound peptide library
FEBS Open Bio
5
429-436
2015
Homo sapiens
Carrie, C.; Venne, A.; Zahedi, R.; Soll, J.
Identification of cleavage sites and substrate proteins for two mitochondrial intermediate peptidases in Arabidopsis thaliana
J. Exp. Bot.
66
2691-2708
2015
BRENDA: Arabidopsis thaliana (W6HYK5), Arabidopsis thaliana
Textmining: Arabidopsis, Saccharomyces cerevisiae
Singh, R.; Goyal, V.D.; Kumar, A.; Sabharwal, N.S.; Makde, R.D.
Crystal structures and biochemical analyses of intermediate cleavage peptidase role of dynamics in enzymatic function
FEBS Lett.
593
443-454
2019
Saccharomyces cerevisiae (P40051), Saccharomyces cerevisiae
Marcondes, M.F.; Alves, F.M.; Assis, D.M.; Hirata, I.Y.; Juliano, L.; Oliveira, V.; Juliano, M.A.
Substrate specificity of mitochondrial intermediate peptidase analysed by a support-bound peptide library
FEBS open bio
5
429-436
2015
Homo sapiens
Carrie, C.; Venne, A.S.; Zahedi, R.P.; Soll, J.
Identification of cleavage sites and substrate proteins for two mitochondrial intermediate peptidases in Arabidopsis thaliana
J. Exp. Bot.
66
2691-2708
2015
Arabidopsis thaliana (F4HZG9), Arabidopsis thaliana, Arabidopsis, Saccharomyces cerevisiae
Huang, S.; Nelson, C.J.; Li, L.; Taylor, N.L.; Stroeher, E.; Peteriet, J.; Millar, A.H.
Intermediate claevage peptidase55 modifies enzyme amino termini and alters protein stability in Arabidopsis mitochondria
Plant Physiol.
168
415-427
2015
BRENDA: Arabidopsis thaliana (F4HZG9)
Textmining: Arabidopsis, Saccharomyces cerevisiae, Transformation
Pena-Diaz, P.; Mach, J.; Kriegova, E.; Poliak, P.; Tachezy, J.; Lukes, J.
Trypanosomal mitochondrial intermediate peptidase does not behave as a classical mitochondrial processing peptidase
PLoS ONE
13
e0196474
2018
Trypanosoma brucei (Q389Z4), Trypanosoma brucei
Chew, A; Sirugo, G; Alsobrook, JP; Isaya, G
Functional and genomic analysis of the human mitochondrial intermediate peptidase, a putative protein partner of frataxin.
Genomics
65
104-12
2000
Homo sapiens, Saccharomyces cerevisiae
Isaya, G; Sakati, WR; Rollins, RA; Shen, GP; Hanson, LC; Ullrich, RC; Novotny, CP
Mammalian mitochondrial intermediate peptidase: structure/function analysis of a new homologue from Schizophyllum commune and relationship to thimet oligopeptidases.
Genomics
28
450-61
1995
Bacteria, eukaryota, Mammalia, Rattus, Saccharomyces cerevisiae, Schizophyllum commune
Chew, A; Buck, EA; Peretz, S; Sirugo, G; Rinaldo, P; Isaya, G
Cloning, expression, and chromosomal assignment of the human mitochondrial intermediate peptidase gene (MIPEP).
Genomics
40
493-6
1997
Homo sapiens, Saccharomyces cerevisiae, Rattus
Branda, SS; Yang, ZY; Chew, A; Isaya, G
Mitochondrial intermediate peptidase and the yeast frataxin homolog together maintain mitochondrial iron homeostasis in Saccharomyces cerevisiae.
Hum Mol Genet
8
1099-110
1999
Saccharomyces cerevisiae, Homo sapiens
James, TY; Kües, U; Rehner, SA; Vilgalys, R
Evolution of the gene encoding mitochondrial intermediate peptidase and its cosegregation with the A mating-type locus of mushroom fungi.
Fungal Genet Biol
41
381-90
2004
Fungi
Singh, R; Jamdar, SN; Goyal, VD; Kumar, A; Ghosh, B; Makde, RD
Structure of the human aminopeptidase XPNPEP3 and comparison of its in vitro activity with Icp55 orthologs: Insights into diverse cellular processes.
J Biol Chem
292
10035-10047
2017
Homo sapiens, Saccharomyces cerevisiae, plant
Kawabata, S; Nakagawa, K; Muta, T; Iwanaga, S; Davie, EW
Rabbit liver microsomal endopeptidase with substrate specificity for processing proproteins is structurally related to rat testes metalloendopeptidase 24.15.
J Biol Chem
268
12498-503
1993
Rattus, Escherichia coli, Saccharomyces cerevisiae
Nett, JH; Schägger, H; Trumpower, BL
Processing of the presequence of the Schizosaccharomyces pombe Rieske iron-sulfur protein occurs in a single step and can be converted to two-step processing by mutation of a single proline to serine in the presequence.
J Biol Chem
273
8652-8
1998
Schizosaccharomyces pombe, Saccharomyces cerevisiae
Nett, JH; Trumpower, BL
Intermediate length Rieske iron-sulfur protein is present and functionally active in the cytochrome bc1 complex of Saccharomyces cerevisiae.
J Biol Chem
274
9253-7
1999
Saccharomyces cerevisiae
Nett, JH; Denke, E; Trumpower, BL
Two-step processing is not essential for the import and assembly of functionally active iron-sulfur protein into the cytochrome bc1 complex in Saccharomyces cerevisiae.
J Biol Chem
272
2212-7
1997
Saccharomyces cerevisiae
Lobo-Hajdu, G; Braun, HP; Romp, N; Grivell, LA; Berden, JA; Schmitz, UK
Subunit VII of ubiquinol:cytochrome-c oxidoreductase from Neurospora crassa is functional in yeast and has an N-terminal extension that is not essential for mitochondrial targeting.
Biochem J
320 ( Pt 3)
769-75
1996
Neurospora crassa
Kües, U; James, TY; Vilgalys, R; Challen, MP
The chromosomal region containing pab-1, mip, and the A mating type locus of the secondarily homothallic homobasidiomycete Coprinus bilanatus.
Curr Genet
39
16-24
2001
Agaricomycetes, Coprinopsis scobicola, Schizophyllum commune
Chen, BZ; Gui, F; Xie, BG; Zou, F; Jiang, YJ; Deng, YJ
Sequence and comparative analysis of the MIP gene in Chinese straw mushroom, Volvariella volvacea.
Genome
2012
Fungi, Volvariella volvacea
Hsiao, CP; Wang, D; Kaushal, A; Saligan, L
Mitochondria-Related Gene Expression Changes Are Associated With Fatigue in Patients With Nonmetastatic Prostate Cancer Receiving External Beam Radiation Therapy.
Cancer Nurs
2012
Homo sapiens
van Diepen, LT; Olson, A; Ihrmark, K; Stenlid, J; James, TY
Extensive trans-specific polymorphism at the mating type locus of the root decay fungus heterobasidion.
Mol Biol Evol
30
2286-301
2013
Heterobasidion, Heterobasidion annosum
Au, CH; Wong, MC; Bao, D; Zhang, M; Song, C; Song, W; Law, PT; Kes, U; Kwan, HS
The genetic structure of the A mating-type locus of Lentinula edodes.
Gene
535
184-90
2014
Agaricomycetes
Calvo, SE; Julien, O; Clauser, KR; Shen, H; Kamer, KJ; Wells, JA; Mootha, VK
Comparative Analysis of Mitochondrial N-Termini from Mouse, Human, and Yeast.
Mol Cell Proteomics
16
512-523
2017
Saccharomyces cerevisiae, Mus musculus
Chitrala, KN; Hernandez, DG; Nalls, MA; Mode, NA; Zonderman, AB; Ezike, N; Evans, MK
Race-specific alterations in DNA methylation among middle-aged African Americans and Whites with metabolic syndrome.
Epigenetics
1-21
2019
Theta
Prel, A; Dozier, C; Combier, JP; Plaza, S; Besson, A
Evidence That Regulation of Pri-miRNA/miRNA Expression Is Not a General Rule of miPEPs Function in Humans.
Int J Mol Sci
22
2021
Homo sapiens, plant
Eldomery, MK; Akdemir, ZC; Vgtle, FN; Charng, WL; Mulica, P; Rosenfeld, JA; Gambin, T; Gu, S; Burrage, LC; Al Shamsi, A; Penney, S; Jhangiani, SN; Zimmerman, HH; Muzny, DM; Wang, X; Tang, J; Medikonda, R; Ramachandran, PV; Wong, LJ; Boerwinkle, E; Gibbs, RA; Eng, CM; Lalani, SR; Hertecant, J; Rodenburg, RJ; Abdul-Rahman, OA; Yang, Y; Xia, F; Wang, MC; Lupski, JR; Meisinger, C; Sutton, VR
MIPEP recessive variants cause a syndrome of left ventricular non-compaction, hypotonia, and infantile death.
Genome Med
8
106
2016
Homo sapiens, Cucumber necrosis virus, Saccharomyces cerevisiae
Stames, EM; O'Toole, JF
Mitochondrial aminopeptidase deletion increases chronological lifespan and oxidative stress resistance while decreasing respiratory metabolism in S. cerevisiae.
PLoS One
8
e77234
2013
Saccharomyces cerevisiae
Coenen, MJ; Smeitink, JA; Smeets, R; Trijbels, FJ; den Heuvel, LP
Mutation detection in four candidate genes (OXA1L, MRS2L, YME1L and MIPEP) for combined deficiencies in the oxidative phosphorylation system.
J Inherit Metab Dis
28
1091-7
2005
Homo sapiens, Saccharomyces cerevisiae
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