Any feedback?
Information on EC 3.4.24.24 - gelatinase A and Organism(s) Homo sapiens and UniProt Accession P08253
for references in articles please use BRENDA:EC3.4.24.24Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
3.4.24.24 gelatinase ASpecify your search results
Word Map
- 3.4.24.24
- mmp-9
- metalloproteinases
-
zymography
- metastasis
- timp-2
- endothelial
- angiogenesis
- artery
- fibrosis
- necrosis
-
gelatinolytic
-
invasiveness
-
transwell
-
basement
- tnf
- mt1-mmp
- plasminogen
- cardiac
- neutrophil
- aortic
- vessel
- integrins
- fibronectin
- upa
- melanoma
- laminin
- matrigel
- vimentin
- myocardial
-
interstitial
- proteinases
- lymph
- ventricular
- e-cadherin
-
nude
-
angiogenic
- aneurysm
- mesenchymal
- stromelysins
-
anti-metastatic
- fak
- medicine
- elastin
- cox-2
- synthesis
- urokinase
- collagenases
-
urokinase-type
-
collagenolytic
- tgf-beta1
- diagnostics
-
lipocalin
-
boyden
The taxonomic range for the selected organisms is: Homo sapiens
The enzyme appears in selected viruses and cellular organisms
The enzyme appears in selected viruses and cellular organisms
Synonyms
mmp-2, gelatinase, matrix metalloproteinase-2, matrix metalloproteinase 2, gelatinase a, type iv collagenase, metalloproteinase-2, progelatinase, collagenase iv, mmp 2, 
more
topPlease wait a moment until the data is sorted. This message will disappear when the data is sorted.
SYNONYM 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
matrix metalloproteinase-2
-
MMP-2
-
72 kDa Gelatinase
-
-
-
-
72 kDa Gelatinase type A
-
-
-
-
72-kDa Gelatinase
Collagenase IV
-
-
-
-
Collagenase type IV
-
-
-
-
gelatinase A
-
-
Matrix metalloproteinase 2
matrix metalloproteinase-2
-
-
MMP 2
-
-
-
-
MMP-2
-
-
Type IV collagen metalloproteinase
-
-
-
-
Type IV collagenase
Type IV collagenase/gelatinase
-
-
-
-
72-kDa Gelatinase
-
-
-
-
Matrix metalloproteinase 2
-
-
-
-
Type IV collagenase
-
-
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
hydrolysis of peptide bond
-
-
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
CAS REGISTRY NUMBER
COMMENTARY
146480-35-5
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
SUBSTRATE
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
(7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-DPA-Ala-Arg-NH2 + H2O
(7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly + Leu-DPA-Ala-Arg-NH2
-
-
-
?
(7-methoxycoumarin-4-yl)acetyl-L-Pro-Leu-Gly-Leu-Dap-Ala-Arg-NH2 + H2O
?
-
a quenched fluorogenic substrate
-
-
?
(7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-2,6-diaminopimelyl-Ala-Arg-NH2 + H2O
?
-
-
-
-
?
(7-methoxycoumarin-4-yl)acetyl-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Lys(2,4-dinitrophenyl)-Gly + H2O
?
-
a short 11-amino-acid collagen-like peptide substrate, NFF-1, cleavage of NFF-1 by MMP-2 does not require CBD-mediated substrate binding for degradation to occur
-
-
?
110000 MW cell-surface amyloid protein precursor + H2O
?
-
amyloid protein precursor of Alzheimer's disease, cleavage to a 1000 MW form of the protein
-
-
?
7-methylcoumaryl-L-Pro-L-Lys-L-Gln-L-Gln-L-Phe-L-Phe-Gly-L-Leu-L-Lys-(2,4-dinitrophenyl)-Gly + H2O
?
-
-
-
-
?
Ac-Pro-Leu-Gly-[2-mercapto-4-methylpentanoyl]-Leu-Gly-OEt + H2O
?
-
-
-
?
Bovine fibrinogen + H2O
?
-
proteolytic processing of bovine fibrinogen bringing about the formation of a product unable to form fibrin clots, preferential binding of MMP-2 to the beta-chain of fibrinogen through its haemopexin-like domain, removal of the domain dramatically alters the proteolytic reaction mechanism, molecular docking and modelling, overview
-
-
?
Dnp-Pro-beta-cyclohexyl-Ala-Gly-Cys(Me)-His-Ala-Lys(N-Me-Abz)-NH2 + H2O
?
-
-
-
?
Galectin-3 + H2O
?
-
a galactoside-binding protein, major cleavage site: Ala62-Tyr63
-
-
?
Gly-Pro-Gln-Gly-Ile-Ala-Gly-Gln + H2O
Gly-Pro-Gln-Gly + Ile-Ala-Gly-Gln
-
-
-
?
Gly-Pro-Gln-Gly-Ile-Ala-Ser-Gln + H2O
Gly-Pro-Gln-Gly + Ile-Ala-Ser-Gln
-
-
-
?
Gly-Pro-Gln-Gly-Ile-Phe-Gly-Gln + H2O
Gly-Pro-Gln-Gly + Ile-Phe-Gly-Gln
-
-
-
?
Gly-Pro-Gln-Gly-Ile-Trp-Gly-Gln + H2O
Gly-Pro-Gln-Gly + Ile-Trp-Gly-Gln
-
-
-
?
LS276-THP + H2O
?
-
development and evaluation of an activatable NIR fluorescent probe LS276-THP for in vivo detection of cancer-related matrix metalloproteinase activity based on a triplehelical peptide substrate with high specificity for MMP-2 and MMP-9 relative to other members of the MMP family, overview. Triple-helical peptides are suitable for highly specific in vivo detection of tumor-related MMP-2 and MMP-9 activity
-
-
?
Mca-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 + H2O
?
-
quenched fluorescent peptide
-
?
Neonatal human proteoglycan + H2O
?
-
cleavage of the His16-Ile17 bond and the Leu25-Leu26 bond
-
-
?
Gelatin + H2O
?
-
-
-
-
?
Gelatin + H2O
?
-
gelatin zymography
-
-
?
additional information
?
-
facilitates tmumor metastasis and angiogenesis by hydrolyzing components of the extracwllular matrix
-
?
additional information
?
-
-
facilitates tmumor metastasis and angiogenesis by hydrolyzing components of the extracwllular matrix
-
?
additional information
?
-
plays a key role in angiogenesis and tumor metastasis
-
?
additional information
?
-
-
plays a key role in angiogenesis and tumor metastasis
-
?
additional information
?
-
the proteinase has the capacity to degrade several extracellular matrix components such as type IV collagens as well as all nonfibrillar collagens, laminin, fibronectin, casein, elastin, and even fibrillar collagens
-
-
?
additional information
?
-
-
the proteinase has the capacity to degrade several extracellular matrix components such as type IV collagens as well as all nonfibrillar collagens, laminin, fibronectin, casein, elastin, and even fibrillar collagens
-
-
?
additional information
?
-
enzyme activity is determined using human teeth as substrate
-
-
?
additional information
?
-
-
specificity: tolerates only small amino acids such as Gly and Ala in subsite P1, prefers hydrophobic, aliphatic residues in subsite P1'
-
-
?
additional information
?
-
-
laminin,native or denatured type I collagen, native or denatured types II, IV, V, and X collagen or the NC1 domain of type VII collagen, elastin,SPARC, tenascin and MatrigelTM are not bound by the recombinant C domain
-
?
additional information
?
-
-
Mca-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2 and DABCYL-Leu-Ala-Gln-Ala-Val-Arg-Ser-Ser-Ser-Arg-EDANS are no substrates
-
?
additional information
?
-
-
may be responsible for the pathological degradation and/or normal turnover of vitronectin
-
-
?
additional information
?
-
-
constitutively expressed in human rheumatoid synovial cells
-
-
?
additional information
?
-
-
activation of progelatinase B is mediated by gelatinase A species that may be localized in the surface of tumor cells and enhance matrix degradation during cancer metastasis
-
-
?
additional information
?
-
-
implicated in tumor cell metastasis and angiogenesis
-
?
additional information
?
-
-
important role in extracellular matrix degradation during cell migration and tissue remodeling, involved in development, inflammation, wound healing, tumor invasion, metastasis and other physiological and pathological processes
-
?
additional information
?
-
-
collagen binding domain is absolutely required for enzyme-dependent cleavage of full-length collagen alpha-chain, but not for short protein fragments such as those generated by hydrolysis of gelatin
-
-
?
additional information
?
-
-
collagen binding domains of matrix metalloproteinases MMP-2 and MMP-9 bind the same or closely positioned sites on type I collagen
-
-
?
additional information
?
-
-
investigation of ligand binding properties of the three fibronectin type II repeats of enzyme using collagen mimic peptide (L-Pro-L-Pro-Gly)6 and propeptide segment PIIKFPGDVA. Each module interacts essentially as an autonomous unit with these peptides, but enzyme shows cooperative participation toward a closer mimic of collagen, ((Gly-L-Pro-L-Pro-)12)3 in triple helical configuration
-
-
?
additional information
?
-
-
activation of MMP-2 may contribute to dentin matrix degradation, which occurs during caries progression and follows rresin bonding. Inhibition of MMP-2 proteolytic activity may slow caries progression and increase the durability of resin-dentin bond, overview
-
-
?
additional information
?
-
-
chitooligosaccharides may play an important role in the prevention and treatment of several MMP-2 mediated health problems such as metastasis and wrinkle formation, overview
-
-
?
additional information
?
-
-
intervertebral disc degeneration is associated with the increased expression of several matrix metalloproteinases, in particular MMP-2, overview
-
-
?
additional information
?
-
-
the enzyme degrades proteins of the extracellular matrix in the uterus and might be involved in the growth of leiomyoma and corresponding myometrium, overview
-
-
?
additional information
?
-
-
TSP-1 acts in LRP-mediated clearance of MMP-2, TIMP-2 complexing leads to MMP-2 accumulation in the cells
-
-
?
additional information
?
-
-
MMP-2 CBD-binding peptides from a random peptide library screening using biotinylated recombinant CBD domain, and interactions of immobilized synthetic peptides with the recombinant CBD, MMP-2E404A, MMP-2DELTACBD and AlkCBD, overview
-
-
?
additional information
?
-
-
the enzyme shows strong interaction with TSP-1 and CBD123, surface plasmon resonance analysis, overview
-
-
?
additional information
?
-
-
kinetic and binding effects in peptide substrate selectivity of matrix metalloproteinase-2, molecular dynamics and QM/MM calculations, computational analysis of binding and hydrolysis reaction by MMP-2 of two peptide substrates selected by the enzyme from a phage peptide library, molecular dynamics simulations of the Michaelis complex, overview
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
Gelatin + H2O
?
-
-
-
-
?
additional information
?
-
facilitates tmumor metastasis and angiogenesis by hydrolyzing components of the extracwllular matrix
-
?
additional information
?
-
-
facilitates tmumor metastasis and angiogenesis by hydrolyzing components of the extracwllular matrix
-
?
additional information
?
-
plays a key role in angiogenesis and tumor metastasis
-
?
additional information
?
-
-
plays a key role in angiogenesis and tumor metastasis
-
?
additional information
?
-
the proteinase has the capacity to degrade several extracellular matrix components such as type IV collagens as well as all nonfibrillar collagens, laminin, fibronectin, casein, elastin, and even fibrillar collagens
-
-
?
additional information
?
-
-
the proteinase has the capacity to degrade several extracellular matrix components such as type IV collagens as well as all nonfibrillar collagens, laminin, fibronectin, casein, elastin, and even fibrillar collagens
-
-
?
additional information
?
-
-
may be responsible for the pathological degradation and/or normal turnover of vitronectin
-
-
?
additional information
?
-
-
constitutively expressed in human rheumatoid synovial cells
-
-
?
additional information
?
-
-
activation of progelatinase B is mediated by gelatinase A species that may be localized in the surface of tumor cells and enhance matrix degradation during cancer metastasis
-
-
?
additional information
?
-
-
implicated in tumor cell metastasis and angiogenesis
-
?
additional information
?
-
-
important role in extracellular matrix degradation during cell migration and tissue remodeling, involved in development, inflammation, wound healing, tumor invasion, metastasis and other physiological and pathological processes
-
?
additional information
?
-
-
collagen binding domain is absolutely required for enzyme-dependent cleavage of full-length collagen alpha-chain, but not for short protein fragments such as those generated by hydrolysis of gelatin
-
-
?
additional information
?
-
-
collagen binding domains of matrix metalloproteinases MMP-2 and MMP-9 bind the same or closely positioned sites on type I collagen
-
-
?
additional information
?
-
-
activation of MMP-2 may contribute to dentin matrix degradation, which occurs during caries progression and follows rresin bonding. Inhibition of MMP-2 proteolytic activity may slow caries progression and increase the durability of resin-dentin bond, overview
-
-
?
additional information
?
-
-
chitooligosaccharides may play an important role in the prevention and treatment of several MMP-2 mediated health problems such as metastasis and wrinkle formation, overview
-
-
?
additional information
?
-
-
intervertebral disc degeneration is associated with the increased expression of several matrix metalloproteinases, in particular MMP-2, overview
-
-
?
additional information
?
-
-
the enzyme degrades proteins of the extracellular matrix in the uterus and might be involved in the growth of leiomyoma and corresponding myometrium, overview
-
-
?
additional information
?
-
-
TSP-1 acts in LRP-mediated clearance of MMP-2, TIMP-2 complexing leads to MMP-2 accumulation in the cells
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
METALS and IONS
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
Ca2+
Zn2+
Ca2+
NaCl
-
4-bladed beta-propeller protein in which the 4 blades are arranged around a channel-like opening in which Ca2+ and a Na+Cl- ion pair are bound
Zn2+
Ca2+
Ca2+is essential for homodimerization of enzyme MMP-2, analysis, detailed overview
Ca2+
essential for gelatinase activity, no gelatinase activity at 1 mM Ca2+
Zn2+
zinc metalloproteinase, the Zn2+-binding motif of the catalytic domain is preceded by three cysteine-rich repeats comparable to the collagen-binding fibronectin type II (FN-II) repeats, which are required for recognizing collagen and elastin
Ca2+
-
4-bladed beta-propeller protein in which the 4 blades are arranged around a channel-like opening in which Ca2+ and a Na+Cl- ion pair are bound
Zn2+
-
required, gelatinase A synthetic 19000 MW catalytic domain, inhibition at high concentration
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
APP-IP-TIMP-2
inhibition evaluation and kinetics, mechanism in concanavalin A-stimulated HT1080 fibrosarcoma cells, expression of APP-IP-TIMP-2 in HT1080 cells, overview. The ten amino acid residue sequence of APP-derived MMP-2 selective inhibitory peptide (APP-IP) is added to the N-terminus of tissue inhibitors of metalloproteinase 2, TIMP-2. The APP-IP and TIMP-2 regions of the fusion protein are designed to interact with the active site and the hemopexin-like domain of MMP-2, respectively.The reactive site of the TIMP-2 region, which has broad specificity against MMPs, is blocked by the APP-IP adduct. The recombinant APP-IP-TIMP-2 shows strong inhibitory activity toward MMP-2 whereas its inhibitory activity toward MMP-1, MMP-3, MMP-7, MMP-8, MMP-9, or MT1--MMP is six orders of magnitude or more weaker. Compared with the decapeptide APP-IP, APP-IP-TIMP-2 shows a much longer half-life in cultured tumor cells
-
isovitexin
interacts with enzyme residues Glu121, Leu83, Ala84, Pro140, Ile141, His120, Ala136, Leu116, Ala139, and Leu137, binding structure analysis, and modelling, overview
N-(R)-(2-(hydroxyaminocarbonyl)methyl)-4-methylpentanoyl-L-naphthylalanyl-L-alanine-2-aminoethyl amide
TAPI-1
TIMP-1
binding also involves interaction between TIMP and the MMP-2 Hpx-like domain
-
TIMP-3
binding also involves interaction between TIMP and the MMP-2 Hpx-like domain
-
TIMP-4
binding also involves interaction between TIMP and the MMP-2 Hpx-like domain
-
tissue inhibitor of metalloproteinases-2
TIMP-2, a physiological inhibitor of MMPs. proMMP-2 can be secreted either in a free form or already complexed with TIMP-2 through its C-terminal domain. In the first case, a TIMP-2 that inhibits a cell membrane-anchored MT1-MMP by interaction between its N-terminal inhibitory domain and the catalytic domain of MT1-MMP, acts as a binding site for free proMMP-2 by interaction between the proMMP-2 Hpx-like domain and the TIMP-2 C-terminal domain. ProMMP-2 present in the resulting MT1-MMP-TIMP-2-proMMP-2 complex can then be activated by another adjacent TIMP-2-free MT1-MMP. In the second case, the N-terminal inhibitory domain of TIMP-2 in the proMMP-2-TIMP-2 complex can interact with a cell membrane-anchored MT1-MMP. This proMMP-2 is then activated by an adjacent free MT1-MMP. To illustrate this process, it has been shown that proMMP-2 colocalizes with TIMP-2 and MT1-MMP inside caveolae on the surface of endothelial cells. Extracellular association of proMMP-2 and TIMP-2 depends on TIMP-2 phosphorylation by extracellular c-Src tyrosine kinase
-
vitexin
interacts with enzyme residues Leu83, Ala84, His130, Pro140, Ala139, Met138, Ala, 136, Leu137, Thr143, Tyr142, Val117, His120, and Ile141, binding structure analysis, and modelling, overview
(2E)-3-(N-hydroxycarbamoyl)-2-(3-phenylpropylidene)propionyl-L-tryptophan-N-methylamide
-
-
(2E)-3-(N-hydroxycarbamoyl)-2-heptylidenepropionyl-L-tryptophan-N-methylamide
-
-
(2E)-3-(N-hydroxycarbamoyl)-2-[(2E)-3-phenylprop-2-en-1-ylidene]propionyl-L-tryptophan-N-methylamide
-
-
(2E)-3-(N-hydroxycarbamoyl)-2-[(2E)-but-2-en-1-ylidene]propionyl-L-tryptophan-N-methylamide
-
-
(2R)-2-[(4-biphenylylcarbonyl)amino]-N-hydroxy-3-(1H-indol-3-yl)propionamide
-
-
(2R)-2-[[4-[benzenesulfonylhydrazonomethyl]benzenesulfonyl]-amino]-3-(1H-indol-3-yl)propionic acid methyl ester
-
-
(2R)-2-[[4-[benzenesulfonylhydrazonomethyl]benzenesulfonyl]-amino]-3-methylbutanoic acid tert-butyl ester
-
-
(2R)-2-[[5-(4-methoxyphenyl)thiophene-2-sulfonyl]-amino]-3-methylbutanoic acid
-
-
(2R)-2-[[5-(4-methoxyphenyl)thiophene-2-sulfonyl]-amino]-3-methylbutanoic acid methyl ester
-
-
(2R)-3-(1H-indol-3yl)-2-[[4-[phenylaminocarbonyl]-benzenesulfonyl]amino]propionic acid benzyl ester
-
-
(2R)-3-methyl-2-[[4-[(4-nitrobenzoyl)-amino]benzenesulfonyl]amino]butanoic acid
-
-
(2R)-3-methyl-2-[[4-[(4-nitrobenzoyl)amino]benzenesulfonyl]amino]butanoic acid tert-butyl ester
-
-
(2R)-3-methyl-2-[[4-[2-[4-methylmercaptophenyl]-2H-tetrazol-5-yl]benzenesulfonyl]-amino]butanoic acid
-
-
(2R)-3-methyl-2-[[4-[2-[methylmercaptophenyl]-2H-tetrazol-5-yl]benzenesulfonyl]-amino]butanoic acid tert-butyl ester
-
-
(2R)-3-methyl-2-[[5-[(4-methylphenyl)ethynyl]thiophene-2-sulfonyl]-amino]butanoic acid methyl ester
-
-
2-(4-(4-[(2-thiiranylpropyl)sulfonyl]phenoxy)phenyl)acetic acid
-
selective inhibitor
2-([4-[3'-(2-aminoethoxy)-2-methylbiphenyl-4-yl]piperidin-1-yl]sulfonyl)-N-hydroxy-2-methylpropanamide
-
-
2-[(4-biphenyl-4-yl-3,6-dihydropyridin-1(2H)-yl)sulfonyl]-N-hydroxyacetamide
-
-
2-[(4-[3'-[2-(dimethylamino)ethoxy]-2-methylbiphenyl-4-yl]piperidin-1-yl)sulfonyl]-N-hydroxy-2-methylpropanamide
-
-
2-[(biphenyl-4-ylsulfonyl)(isobutyl)amino]-N-hydroxyacetamide
-
50% inhibition at 13 nM, comparison with inhibitory effect on matrix metalloproteinases MMP-3, MMp-7, MMP-9
2-[(biphenyl-4-ylsulfonyl)(isopropoxy)amino]-N-hydroxyacetamide
-
50% inhibition at 12 nM, comparison with inhibitory effect on matrix metalloproteinases MMP-3, MMp-7, MMP-9
2-[[4-(2,3'-dimethylbiphenyl-4-yl)-3,6-dihydropyridin-1(2H)-yl]sulfonyl]-N-hydroxyacetamide
-
-
2-[[4-(2-chlorobiphenyl-4-yl)-3,6-dihydropyridin-1(2H)-yl]sulfonyl]-N-hydroxyacetamide
-
-
2-[[4-(2-ethylbiphenyl-4-yl)-3,6-dihydropyridin-1(2H)-yl]sulfonyl]-N-hydroxyacetamide
-
-
2-[[4-(2-fluorobiphenyl-4-yl)-3,6-dihydropyridin-1(2H)-yl]sulfonyl]-N-hydroxyacetamide
-
-
2-[[4-(3'-ethoxy-2-methylbiphenyl-4-yl)-3,6-dihydropyridin-1(2H)-yl]sulfonyl]-N-hydroxyacetamide
-
-
2-[[4-(3'-ethoxy-2-methylbiphenyl-4-yl)piperidin-1-yl]sulfonyl]-N-hydroxy-2-methylpropanamide
-
-
2-[[4-(3'-ethyl-2-methylbiphenyl-4-yl)-3,6-dihydropyridin-1(2H)-yl]sulfonyl]-N-hydroxyacetamide
-
-
advanced glycation products
-
inhibit the enzyme mediated through upregulation of the advanced glycation product receptor, overview
-
Ag-3340
-
i.e. N-hydroxy-2,2-dimethyl-4-[(4-phenoxyphenyl)sulfonyl]thiomorpholine-3-carboxamide, 50% inhibition at 0.083 nM, comparison with inhibitory effect on matrix metalloproteinases MMP-3, MMp-7, MMP-9
CGS27023A
-
50% inhibition at 20 nM, comparison with inhibitory effect on matrix metalloproteinases MMP-3, MMp-7, MMP-9
chitooligosaccharides
-
inhibit MMP-2 enzyme expression, decrease of the gene expression and transcriptional activity of MMP-2, and catalytic activity in primary dermal fibroblasts, chitooligosaccharides of 3-5 kDa are most effective
dimethyl sulfoxide
-
presence of 2% dimethyl sulfoxide disrupts interactions of enzyme with substrate and thereby reduces activity by 70%
extracellular domain of beta-amyloid peptide
-
the extracellular domain of beta-amyloid precursor protein contains an inhibitor against MMP-2, the inhibitor is localized within the ISYGNDALMP sequence of APP, overview
-
methyl 2-(4-(4-[(2-thiiranylpropyl)-sulfonyl]phenoxy)phenyl)acetate
-
mechanism-based inhibitor, selective for enzyme
N-hydroxy-2-(isobutyl[(4-methoxyphenyl)sulfonyl]amino)acetamide
-
50% inhibition at 6.9 nM, comparison with inhibitory effect on matrix metalloproteinases MMP-3, MMp-7, MMP-9
N-hydroxy-2-([4-[2-(trifluoromethyl)biphenyl-4-yl]-3,6-dihydropyridin-1(2H)-yl]sulfonyl)acetamide
-
-
N-hydroxy-2-([4-[2-methyl-3'-(trifluoromethoxy)biphenyl-4-yl]-3,6-dihydropyridin-1(2H)-yl]sulfonyl)acetamide
-
-
N-hydroxy-2-([4-[3'-(2-hydroxyethoxy)-2-methylbiphenyl-4-yl]piperidin-1-yl]sulfonyl)-2-methylpropanamide
-
-
N-hydroxy-2-([4-[3'-(2-methoxyethoxy)-2-methylbiphenyl-4-yl]piperidin-1-yl]sulfonyl)-2-methylpropanamide
-
-
N-hydroxy-2-([4-[3'-(methoxymethyl)-2-methylbiphenyl-4-yl]-3,6-dihydropyridin-1(2H)-yl]sulfonyl)acetamide
-
-
N-hydroxy-2-methyl-2-[(4-[2-methyl-3'-[2-(methylamino)ethoxy]biphenyl-4-yl]piperidin-1-yl)sulfonyl]propanamide
-
-
N-hydroxy-2-[(4-[4-[6-(2-hydroxyethoxy)pyridin-2-yl]-3-methylphenyl]piperidin-1-yl)sulfonyl]-2-methylpropanamide
-
-
N-hydroxy-2-[[4-(2-methylbiphenyl-4-yl)-3,6-dihydropyridin-1(2H)-yl]sulfonyl]acetamide
-
-
N-hydroxy-2-[[4-(3'-methoxy-2-methylbiphenyl-4-yl)-3,6-dihydropyridin-1(2H)-yl]sulfonyl]acetamide
-
-
peptide P713
-
inhibits the binding of the CBD as well as MMP-2E404A to gelatin, no inhibition of MMP-2 lacking thr CBD domain, competitively, P713 inhibits MMP-2 activities by blocking substrate access to the CBD exodomain, mechanism, overview
-
procyanidin oligomers
-
from Japanese quince, Chaenomeles japonica, fruit inhibit activity of MMP-2
-
Stromelysin catalytic domain inhibitors
-
gelatinase A synthetic 19000 MW catalytic domain
-
tissue inhibitor of metalloproteinases-2
-
TIMP-2, complex formation with MMP-14 and MMP-2 activates the enzyme, overview
-
Zn2+
-
required, synthetic 19000 MW catalytic domain, inhibition at high concentration
ISYGNDALMP
-
APP-derived inhibitory peptide, APP-IP, selective inhibition of MMP-2, An MMP-2 mutant, with deleted hemopexin-like domain and three fibronectin-like type II domains, and native MMP-2 showed similar affinities for APP-IP, suggesting that only the catalytic domain of MMP-2 is essential for the interaction, mutational interaction analysis, overview, inhibition of recombinant wild-type enzyme and truncated enzyme mutants, overview
Tissue inhibitor of metalloproteinase-2
-
activity of the inhibitor is regulated by C-terminal domain interactions
-
Tissue inhibitor of metalloproteinase-2
-
purification and characterization of a two-chain form of the inhibitor and a low MW TIMP-like protein, proteolytic processing of TIMP-2 plays a role in the regulation of gelatinase A in the extracellular matrix
-
Tissue inhibitor of metalloproteinase-2
-
TIMP-2, not only a potent inhibitor of the activated enzyme but also prevents the generation of low-molecular-mass species and full enzymic activity from the zymogen
-
additional information
enzyme residue Cys102 plays a role in inhibition of catalytic activity through a cysteine-zinc ion pairing, this pairing is disrupted by the intermolecular disulfide bond in the MMP-2 homodimer, resulting in enzyme activation. Disruption of the cysteine-zinc ion pairing by homodimerization of MMP-2 opens the active site, but it may accommodate only small peptide substrates. Thus, MMP-2 propeptide processing is a prerequisite to gain its proteolytic activity against large substrates, including gelatin
-
additional information
molecular design of a highly selective and strong protein inhibitor against matrix metalloproteinase-2, overview
-
additional information
Ficus deltoidea leaf extract inhibits matrix metalloproteinase-2, 8 and 9, molecular docking, molecular dynamics, molecular dynamic simulation analysis, overview. Computational docking analysis reveals that vitexin and isovitexin binds to the active site of the three tested MMPs
-
additional information
omega-3 and omega-6 fatty acids act as inhibitors of matrix metalloproteinase-2 activity. Omega-3 and omega-6 fatty acids contribute to the structure and function of the phospholipid bilayers in cellular membranes and act as precursors of lipid-mediated signaling molecules
-
additional information
while TIMP-2, TIMP-3 and TIMP-4 are able to strongly interact with proMMP-2, TIMP-2 is the only one contributing to cell-surface activation of the proenzyme by MT1-MMP. Such antagonistic properties of TIMP-2 (inhibition vs. activation) highlight its seminal role in the control of pericellular MMP-2 activity
-
additional information
-
not: inhibitors of serine, cysteine or aspartic proteinases
-
additional information
-
dithiothreitol does not interfere with heparin binding
-
additional information
-
allyl isothiocyanate and N-acetylcysteinyl-allyl isothiocyanate downregulate MMP-2 expression in SK-Hep1 hepatoma cells, as well as adhesion, invasion, and migration, overview
-
additional information
-
CBD123 decreases active MMP-2 levels in HT-1080 cells, but only marginally the content of pro-MMP-2, overview
-
additional information
-
inhibition of MMP-2 gelatinolysis by targeting exodomain-substrate interactions
-
additional information
-
inhibition potency of sulfur-containing compounds, overview
-
additional information
-
simultaneous binding of each ligand heparan sulfate and hirudin to the exosites is necessary for the complete inhibition of MMP-2 degradation by thrombin
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
prostaglandin E2
PGE2, significantly increases MMP-2 activity as well as tube formation in endothelial cells. The PGE2-mediated elevation of MMP-2 activity is associated with the pro-angiogenic responses
tissue inhibitor of metalloproteinases-2
TIMP-2, a physiological inhibitor of MMPs. proMMP-2 can be secreted either in a free form or already complexed with TIMP-2 through its C-terminal domain. In the first case, a TIMP-2 that inhibits a cell membrane-anchored MT1-MMP by interaction between its N-terminal inhibitory domain and the catalytic domain of MT1-MMP, acts as a binding site for free proMMP-2 by interaction between the proMMP-2 Hpx-like domain and the TIMP-2 C-terminal domain. ProMMP-2 present in the resulting MT1-MMP-TIMP-2-proMMP-2 complex can then be activated by another adjacent TIMP-2-free MT1-MMP. In the second case, the N-terminal inhibitory domain of TIMP-2 in the proMMP-2-TIMP-2 complex can interact with a cell membrane-anchored MT1-MMP. This proMMP-2 is then activated by an adjacent free MT1-MMP. To illustrate this process, it has been shown that proMMP-2 colocalizes with TIMP-2 and MT1-MMP inside caveolae on the surface of endothelial cells. Extracellular association of proMMP-2 and TIMP-2 depends on TIMP-2 phosphorylation by extracellular c-Src tyrosine kinase
-
membrane-type 1 matrix metalloproteinase
-
activity in the extracellular environment is modulated by this activator
-
MMP-14
-
MMP-14 activates MMP-2 during degeneration of invertebral disc, a major activation pathway of MMP-2 involves complex formation with MMP-14 and a tissue inhibitor of metalloproteinases-2, TIMP-2, overview
-
syndecan-1
-
expression of syndecan-1 increases thrombin-mediated activation of pro-MMP-2 in K562 cells
-
thrombin
-
dependent on, molecular mechanisms underlying thrombin-mediated MMP-2 activation, overview. Interaction of MMP-2 with exosites 1 and 2 of thrombin is crucial for thrombin- mediated MMP-2 degradation, and inhibition of this interaction by heparan sulfate or hirudin fragment results in a decrease in MMP-2 degradation, interaction between exosite 1 and hemopexin-like domain of MMP-2
-
additional information
heparan sulfate is required for thrombin-mediated activation of pro-MMP-2 by binding to thrombin, presumably through conformational changes at the active site of the enzyme. Homodimerization of the enzyme enhances thrombin-mediated activation of pro-MMP-2. Enzyme residue Cys102 plays a role in inhibition of catalytic activity through a cysteine-zinc ion pairing, this pairing is disrupted by the intermolecular disulfide bond in the MMP-2 homodimer, resulting in enzyme activation. Disruption of the cysteine-zinc ion pairing by homodimerization of MMP-2 opens the active site, but it may accommodate only small peptide substrates. Thus, MMP-2 propeptide processing is a prerequisite to gain its proteolytic activity against large substrates, including gelatin
-
additional information
involvement of MT1MMP and TIMP-2 in MMP-2 activation during progression of endometriosis, overview
-
additional information
-
involvement of MT1MMP and TIMP-2 in MMP-2 activation during progression of endometriosis, overview
-
additional information
-
rapid activation of the zymogen by 4-aminophenylmercuric acetate
-
additional information
-
no activation by endopeptidases (trypsin, chymotrypsin, plasmin, plasma kallikrein, thrombin, neutrophil elastase, cathepsin G, matrix metalloproteinase 3, thermolysin)
-
additional information
-
interaction of the zymogen with fetuin or asialofetuin results in cleavage to lower MW forms and activation
-
additional information
-
activation of pro-MMP-2 by 4-aminophenylmercuric acetate
-
additional information
-
sonicated bacterial extract from Porphyromonas gingivalis (0.0001 mg/ml at 37°C for 18 h) activates MMP-2
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Aberrant Crypt Foci
Anti-inflammatory and anticancer effects of p-methoxycinnamic acid, an active phenylpropanoid, against 1,2-dimethylhydrazine-induced rat colon carcinogenesis.
Abortion, Habitual
Altered expression of genes involved in the production and degradation of endometrial extracellular matrix in patients with unexplained infertility and recurrent miscarriages.
Abortion, Spontaneous
The association of polymorphisms in promoter region of MMP2 and MMP9 with recurrent spontaneous abortion risk in Chinese population.
Abscess
Anti-MMP-9 Antibody: A Promising Therapeutic Strategy for Treatment of Inflammatory Bowel Disease Complications with Fibrosis.
Abscess
The zymographic evaluation of gelatinase (MMP-2 and -9) levels in acute and chronic periapical abscesses.
Acne Vulgaris
A comparative study of MMP-1, MMP-2, and TNF-? expression in different acne vulgaris lesions.
Acne Vulgaris
Hypertrophic post-acne scarring is associated with a single nucleotide polymorphism (rs243865) in the matrix metalloproteinase-2 gene.
Acne Vulgaris
Polymorphisms in the promoters of MMP-2 and TIMP-2 genes in patients with acne vulgaris.
Acne Vulgaris
Role of MMP-2(-1306 C/T) and TIMP-2(-418G/C) Polymorphism in Chinese Han Patients with Acne Vulgaris.
Acquired Immunodeficiency Syndrome
Determination of MMP-2 and -9 activities in synovial fluid of horses with osteoarthritic and arthritic joint diseases using gelatin zymography and immunocapture activity assays.
Acquired Immunodeficiency Syndrome
Expression levels of matrix metalloproteinase (MMP)-9 and its specific inhibitor TIMP-1, in septic and aseptic arthritis of the knee.
Acquired Immunodeficiency Syndrome
Increased activity of matrix metalloproteinases in the cerebrospinal fluid of patients with HIV-associated neurological diseases.
Acquired Immunodeficiency Syndrome
Lentivirus infection in the brain induces matrix metalloproteinase expression: role of envelope diversity.
Acquired Immunodeficiency Syndrome
MMP2 expression is a prognostic marker for primary melanoma patients.
Acquired Immunodeficiency Syndrome
Modulation of MMP-2 and MMP-9 through connected pathways and growth factors is critical for extracellular matrix balance of intra-articular ligaments.
Acquired Immunodeficiency Syndrome
Molecular dynamics simulation study on the interaction of collagen like peptides with gelatinase-a (mmp-2).
Acquired Immunodeficiency Syndrome
The EGF signaling pathway influences cell migration and the secretion of metalloproteinases by myoepithelial cells in pleomorphic adenoma.
Acromegaly
Matrix metalloproteinase 2 (MMP-2) levels are increased in active acromegaly patients.
Acromegaly
Reductions of circulating matrix metalloproteinase 2 and vascular endothelial growth factor levels after treatment with pegvisomant in subjects with acromegaly.
Acute Coronary Syndrome
Cardiometabolic risk factors and acute kidney injury based on urinary neutrophil gelatinase associated lipocalin (NGALu) in acute coronary syndrome patients.
Acute Coronary Syndrome
Comparison between metalloproteinases-2 and -9 in healthy subjects, diabetics, and subjects with acute coronary syndrome.
Acute Coronary Syndrome
Estimating the prevalence of elevated plasma neutrophil gelatinase associated lipocalin level in patients with acute coronary syndromes and its association with outcomes.
Acute Coronary Syndrome
Expressions and clinical significance of factors related to acute coronary syndrome.
Acute Coronary Syndrome
Matrix Metalloproteinase-2 predicts mortality in patients with acute coronary syndrome.
Acute Coronary Syndrome
Metalloproteinase-2 and -9 in diabetic and nondiabetic subjects during acute coronary syndromes.
Acute Coronary Syndrome
Metalloproteinases-2, -9 and TIMP-1 expression in stable and unstable coronary plaques undergoing PCI.
Acute Coronary Syndrome
MiR-29b mimics promotes cell apoptosis of smooth muscle cells via targeting on MMP-2.
Acute Coronary Syndrome
Platelets release matrix metalloproteinase-2 in the coronary circulation of patients with acute coronary syndromes: possible role in sustained platelet activation.
Acute Coronary Syndrome
Serum levels of neutrophil Gelatinase associated Lipocalin (NGAL) predicts hemodialysis after coronary angiography in high risk patients with acute coronary syndrome.
Acute Coronary Syndrome
Transcription activity of MMP-2 and MMP-9 metalloproteinase genes and their tissue inhibitor (TIMP-2) in acute coronary syndrome patients.
Acute Coronary Syndrome
[Changes in serum level of carboxy-terminal telopeptide of type I collagen in patients with coronary heart disease].
Acute Kidney Injury
An E-selectin targeting and MMP-2-responsive dextran-curcumin polymeric prodrug for targeted therapy of acute kidney injury.
Acute Kidney Injury
An intracellular matrix metalloproteinase-2 isoform induces tubular regulated necrosis: implications for acute kidney injury.
Acute Kidney Injury
Can We Use Tissue Inhibitor Metalloproteinase-2 and Insulin-Like Growth Factor Binding Protein-7 Levels to Predict Acute Kidney Injury in Neonate and Infants Undergoing Cardiac Surgery? Not Yet
.
Acute Kidney Injury
Cardiometabolic risk factors and acute kidney injury based on urinary neutrophil gelatinase associated lipocalin (NGALu) in acute coronary syndrome patients.
Acute Kidney Injury
Cell Cycle Biomarkers and Soluble Urokinase-Type Plasminogen Activator Receptor for the Prediction of Sepsis-Induced Acute Kidney Injury Requiring Renal Replacement Therapy: A Prospective, Exploratory Study.
Acute Kidney Injury
Comparison of urinary TIMP-2 and IGFBP7 cut-offs to predict acute kidney injury in critically ill patients: A PRISMA-compliant systematic review and meta-analysis.
Acute Kidney Injury
Diagnostic accuracy of urine neutrophil gelatinase-associated lipocalin and urine kidney injury molecule-1 as predictors of acute pyelonephritis in young children with febrile urinary tract infection.
Acute Kidney Injury
Diagnostic value of urinary tissue inhibitor of metalloproteinase-2 and insulin-like growth factor binding protein 7 for acute kidney injury: a meta-analysis.
Acute Kidney Injury
Diagnostic Value of Urine Tissue Inhibitor of Metalloproteinase-2 and Insulin-Like Growth Factor-Binding Protein 7 for Acute Kidney Injury: A Meta-Analysis.
Acute Kidney Injury
Early Diagnosis Of Acute Kidney Injury By Urinary Neutrophil Gelatinase Associated Lipocalin In Adult Critically Ill Patients.
Acute Kidney Injury
Effect of pentoxifylline on preventing acute kidney injury after cardiac surgery by measuring urinary neutrophil gelatinase - associated lipocalin.
Acute Kidney Injury
Epidemiology of acute kidney injury and the role of urinary [TIMP-2]·[IGFBP7]: a prospective cohort study in critically ill obstetric patients.
Acute Kidney Injury
Estimation of urine neutrophil gelatinase associated lipocalin in septic patients with and without acute kidney injury.
Acute Kidney Injury
Evaluation of NGAL Test, a fully-automated neutrophil gelatinase-associated lipocalin (NGAL) immunoassay on Beckman Coulter AU 5822.
Acute Kidney Injury
Evaluation of urinary tissue inhibitor of metalloproteinase-2 in acute kidney injury: a prospective observational study.
Acute Kidney Injury
Furosemide versus ethacrynic acid in pediatric patients undergoing cardiac surgery: a randomized controlled trial.
Acute Kidney Injury
Hepatic ischemia-reperfusion injury associates with acute kidney injury in liver transplantation: Prospective cohort study.
Acute Kidney Injury
IL-6-mediated hepatocyte production is the primary source of plasma and urine neutrophil gelatinase-associated lipocalin during acute kidney injury.
Acute Kidney Injury
Importance of determination of urine neutrophile gelatinase associated lipocalin in early detection of acute kidney injury.
Acute Kidney Injury
Inhibition of matrix metalloproteinases reduces ischemia-reperfusion acute kidney injury.
Acute Kidney Injury
Ischemia-reperfusion injury stimulates gelatinase expression and activity in kidney glomeruli.
Acute Kidney Injury
Kinetics of the cell cycle arrest biomarkers (TIMP-2*IGFBP-7) for prediction of acute kidney injury in infants after cardiac surgery.
Acute Kidney Injury
Kinetics of Urinary Cell Cycle Arrest Markers for Acute Kidney Injury Following Exposure to Potential Renal Insults.
Acute Kidney Injury
MMP-2 and MMP-9 levels in plasma are altered and associated with mortality in COVID-19 patients.
Acute Kidney Injury
Neutrophil Gelatinase Associated Lipocalin (NGAL) in Leptospirosis Acute Kidney Injury: A Multicenter Study in Thailand.
Acute Kidney Injury
Neutrophil Gelatinase Associated Lipocalin as a Biomarker for Acute Kidney Injury in Patients Undergoing Coronary Artery Bypass Grafting with Cardiopulmonary Bypass.
Acute Kidney Injury
Neutrophil gelatinase associated lipocalin as an indicator of acute kidney injury and inflammation in burned children.
Acute Kidney Injury
Neutrophil Gelatinase Associated Lipocalin is an Independent Predictor of Poor Prognosis in Cases of Papillary Renal Cell Carcinoma.
Acute Kidney Injury
Novel renal markers for the assessment of renal integrity in patients undergoing knee arthroplasty - a pilot study.
Acute Kidney Injury
Plasma Neutrophil Gelatinase Associated Lipocalin (NGAL) - Early Biomarker for Acute Kidney Injury in Critically Ill Patients.
Acute Kidney Injury
Plasma Neutrophil Gelatinase Associated Lipocalin Diagnosed Acute Kidney Injury in Patients With Systemic Inflammatory Disease And Sepsis.
Acute Kidney Injury
Predicting Severity of Acute Kidney Injury in Term Neonates with Perinatal Asphyxia Using Urinary Neutrophil Gelatinase Associated Lipocalin.
Acute Kidney Injury
Renal neutrophil gelatinase associated lipocalin expression in lipopolysaccharide-induced acute kidney injury in the rat.
Acute Kidney Injury
Reversibility of Acute Kidney Injury in Medical ICU Patients: Predictability Performance of Urinary Tissue Inhibitor of Metalloproteinase-2 x Insulin-Like Growth Factor-Binding Protein 7 and Renal Resistive Index.
Acute Kidney Injury
Role of matrix metalloproteinase-2 in recovery after tubular damage in acute kidney injury in mice.
Acute Kidney Injury
Serial Urinary Tissue Inhibitor of Metalloproteinase-2 and Insulin-Like Growth Factor-Binding Protein 7 and the Prognosis for Acute Kidney Injury over the Course of Critical Illness.
Acute Kidney Injury
Serum and Plasma Neutrophil Gelatinase Associated Lipocalin (NGAL) Levels are Not Equivalent in Patients Admitted to Intensive Care.
Acute Kidney Injury
Serum neutrophil gelatinase associated lipocalin (NGAL) and cystatin C as early predictors of contrast-induced acute kidney injury in patients undergoing percutaneous coronary intervention.
Acute Kidney Injury
Serum Neutrophil Gelatinase Associated Lipocalin (NGAL) Outperforms Serum Creatinine in Detecting Sepsis-Induced Acute Kidney Injury, Experiments on Bilateral Nephrectomy and Bilateral Ureter Obstruction Mouse Models.
Acute Kidney Injury
The effect of early renal replacement therapy guided by plasma neutrophil gelatinase associated lipocalin on outcome of acute kidney injury: A feasibility study.
Acute Kidney Injury
The effectiveness of urinary TIMP-2 and IGFBP-7 in predicting acute kidney injury in critically ill neonates.
Acute Kidney Injury
The use of plasma and urine neutrophil gelatinase associated lipocalin (NGAL) and Cystatin C in early diagnosis of septic acute kidney injury in critically ill patients.
Acute Kidney Injury
Tissue inhibitor metalloproteinase-2 (TIMP-2) IGF-binding protein-7 (IGFBP7) levels are associated with adverse outcomes in patients in the intensive care unit with acute kidney injury.
Acute Kidney Injury
Ultra-high-performance liquid chromatography-mass spectrometry method for neutrophil gelatinase-associated lipocalin as a predictive biomarker in acute kidney injury.
Acute Kidney Injury
Urinary Kidney Injury Molecule-1 but Not Urinary Neutrophil Gelatinase Associated Lipocalin Is Increased after Short Maximal Exercise.
Acute Kidney Injury
Urinary Neutrophil Gelatinase Associated Lipocalin (NGAL) for Early Diagnosis of Acute Kidney Injury in Renal Transplant Recipients.
Acute Kidney Injury
Urinary neutrophil gelatinase associated lipocalin as a biomarker in ifosfamide induced chronic renal failure.
Acute Kidney Injury
Urinary Neutrophil Gelatinase Associated Lipocalins (NGALs) predict acute kidney injury post liver transplant.
Acute Kidney Injury
Urinary Tissue Inhibitor of Metalloproteinase and Insulin-like Growth Factor-7 as Early Biomarkers of Delayed Graft Function After Kidney Transplantation.
Acute Kidney Injury
Urinary Tissue Inhibitor of Metalloproteinase-2 (TIMP-2) Insulin-Like Growth Factor-Binding Protein 7 (IGFBP7) Predicts Adverse Outcome in Pediatric Acute Kidney Injury.
Acute Kidney Injury
Urinary tissue inhibitor of metalloproteinase-2 and insulin-like growth factor-binding protein 7 as biomarkers of patients with established acute kidney injury.
Acute Kidney Injury
Urinary Tissue Inhibitor of Metalloproteinase-2 and Insulin-Like Growth Factor-Binding Protein 7 for Risk Stratification of Acute Kidney Injury in Patients With Sepsis.
Acute Kidney Injury
Urine neutrophil gelatinase associated lipocalin as an early marker of acute kidney injury in hematopoietic stem cell transplantation patients.
Acute Kidney Injury
Urine neutrophil gelatinase-associated lipocalin levels predict acute kidney injury in acute decompensated heart failure patients.
Acute Kidney Injury
Urine/Plasma Neutrophil Gelatinase Associated Lipocalin Ratio Is a Sensitive and Specific Marker of Subclinical Acute Kidney Injury in Mice.
Acute Kidney Injury
Value of point-of-care neutrophil gelatinase associated lipocalin in early diagnosis of acute kidney injury in patients with left ventricular systolic dysfunction after coronary angiography.
Acute Kidney Injury
[Urinary neutrophil gelatinase-associated lipocalin (uNGAL) and early diagnosis of paraquat poisoning patients with acute kidney injury].
Acute Lung Injury
3, 4-dihydroxybenzalacetone attenuates lipopolysaccharide-induced inflammation in acute lung injury via down-regulation of MMP-2 and MMP-9 activities through suppressing ROS-mediated MAPK and PI3K/AKT signaling pathways.
Acute Lung Injury
A rise of MMP-2 and MMP-9 in bronchoalveolar lavage fluid is associated with acute lung injury after cardiopulmonary bypass in a swine model.
Acute Lung Injury
Depsipeptide a histone deacetlyase inhibitor down regulates levels of matrix metalloproteinases 2 and 9 mRNA and protein expressions in lung cancer cells (A549).
Acute Lung Injury
Dexamethasone Ameliorates H2S-Induced Acute Lung Injury by Alleviating Matrix Metalloproteinase-2 and -9 Expression.
Acute Lung Injury
Increased production of matrix metalloproteinase-2 in alveolar macrophages and regulation by interleukin-10 in patients with acute pulmonary sarcoidosis.
Acute Lung Injury
Involvement of lung interstitial proteoglycans in development of hydraulic- and elastase-induced edema.
Acute Lung Injury
Ionizing radiation enhances matrix metalloproteinase-2 production in human lung epithelial cells.
Acute Lung Injury
Matrix metalloproteinases and matrix metalloproteinase inhibitors in acute lung injury.
Acute Lung Injury
Metalloproteinase inhibition reduces lung injury and improves survival after cecal ligation and puncture in rats.
Acute Lung Injury
Novel 5-Hydroxy, 5-Substituted Benzenesulfonamide Pyrimidine-2,4,6-Triones Attenuate Lipopolysaccharide-Induced Acute Lung Injury via Inhibition of the Gelatinases, MMP-2 and MMP-9.
Acute Lung Injury
Role of gelatinases MMP-2 and MMP-9 in tissue remodeling following acute lung injury.
Acute Lung Injury
The endothelin axis and gelatinase activity in alveolar macrophages after brain-stem death injury: a pilot study.
Acute Lung Injury
[Effects of adenovirus-delivered angiopoietin-1 siRNA on expression of matrix metalloproteinases in rats with acute lung injury induced by phosgene].
Acute Lung Injury
[Effects of unfractionated heparin on expression of metalloproteinase-2 and -9 in acute lung injury rats].
Acute Lung Injury
[Expression of various matrix metalloproteinases in mice with hyperoxia induced acute lung injury.]
Adenocarcinoma
A functional polymorphism in the matrix metalloproteinase-2 gene promoter (-1306C/T) is associated with risk of development but not metastasis of gastric cardia adenocarcinoma.
Adenocarcinoma
A plasma membrane-associated component of ovarian adenocarcinoma cells enhances the catalytic efficiency of matrix metalloproteinase-2.
Adenocarcinoma
alpha-Mangostin, a novel dietary xanthone, suppresses TPA-mediated MMP-2 and MMP-9 expressions through the ERK signaling pathway in MCF-7 human breast adenocarcinoma cells.
Adenocarcinoma
Analyses of matrix metalloproteinases and their inhibitors in cyst fluid of serous ovarian tumors.
Adenocarcinoma
Analysis of the capillary architecture in the precursors of prostate cancer: recent findings and new concepts.
Adenocarcinoma
Characterization of gelatinases linked to extracellular matrix invasion in ovarian adenocarcinoma: purification of matrix metalloproteinase 2.
Adenocarcinoma
Circulating levels of VCAM and MMP-2 may help identify patients with more aggressive prostate cancer.
Adenocarcinoma
Clinicopathologic and prognostic significance of matrix metalloproteinases in rectal cancer.
Adenocarcinoma
Correlation between expression of matrix metalloproteinase-2 (MMP-2), and matrix metalloproteinase-9 (MMP-9) and angiogenesis in colorectal adenocarcinoma.
Adenocarcinoma
Differential expression and origin of membrane-type 1 and 2 matrix metalloproteinases (MT-MMPs) in association with MMP2 activation in injured human livers.
Adenocarcinoma
Differential expression of matrix metalloproteinase (MMP)-2, MMP-9, and membrane type 1-MMP in hepatocellular and pancreatic adenocarcinoma: implications for tumor progression and clinical prognosis.
Adenocarcinoma
Distinct endobronchial expression of matrix-metalloproteinases (MMP) and their endogenous inhibitors in lung cancer.
Adenocarcinoma
Effects of EGF and TGF-alpha on invasion and proteinase expression of uterine cervical adenocarcinoma OMC-4 cells.
Adenocarcinoma
Effects of sex steroids and growth factors on migration and invasion of endometrial adenocarcinoma SNG-M cells in vitro.
Adenocarcinoma
Epithelial MMP-2 expression correlates with worse prognosis in pancreatic cancer.
Adenocarcinoma
Evaluation of MMP-9 and MMP-2 and their suppressor TIMP-1 and TIMP-2 in adenocarcinoma of esophagogastric junction.
Adenocarcinoma
Expression analysis and clinical significance of eIF4E, VEGF-C, E-cadherin and MMP-2 in colorectal adenocarcinoma.
Adenocarcinoma
Expression of 72 kilodalton type IV collagenase (gelatinase A) in benign and malignant ovarian tumors.
Adenocarcinoma
Expression of Fhit, cell adhesion molecules and matrix metalloproteinases in atypical adenomatous hyperplasia and pulmonary adenocarcinoma.
Adenocarcinoma
Expression of gelatinase A, tissue inhibitor of metalloproteinases-2, matrilysin, and trypsin(ogen) in lung neoplasms: an immunohistochemical study.
Adenocarcinoma
Expression of matrix metalloproteinase (gelatinase) in T1 adenocarcinoma of the lung.
Adenocarcinoma
Expression of matrix metalloproteinase 2 (MMP-2), membrane-type 1 MMP and tissue inhibitor of metalloproteinase 2 and activation of proMMP-2 in pancreatic duct adenocarcinomas in hamsters treated with N-nitrosobis(2-oxopropyl)amine.
Adenocarcinoma
Expression of matrix metalloproteinase-2 (mmp-2) in cervical neoplasia - immunohistochemical and in-situ hybridization studies.
Adenocarcinoma
Expression of matrix metalloproteinases and tissue inhibitor of matrix metalloproteinases in non-small-cell lung cancer.
Adenocarcinoma
Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human pancreatic adenocarcinomas: clinicopathologic and prognostic significance of matrilysin expression.
Adenocarcinoma
Expression of metalloproteinases and their inhibitors in adenocarcinoma of the uterine cervix.
Adenocarcinoma
Expression of PI3K/AKT pathway in gastric cancer and its blockade suppresses tumor growth and metastasis.
Adenocarcinoma
Expression of tissue levels of matrix metalloproteinases and tissue inhibitors of metalloproteinases in gastric adenocarcinoma.
Adenocarcinoma
Expression of Yes-associated protein in gastric adenocarcinoma and inhibitory effects of its knockdown on gastric cancer cell proliferation and metastasis.
Adenocarcinoma
Expression profiling using a cDNA array and immunohistochemistry for the extracellular matrix genes FN-1, ITGA-3, ITGB-5, MMP-2, and MMP-9 in colorectal carcinoma progression and dissemination.
Adenocarcinoma
Expressions of Matrix Metalloproteinases 2, 7, and 9 in Carcinogenesis of Pancreatic Ductal Adenocarcinoma.
Adenocarcinoma
Extracellular matrix expression in metastasizing and nonmetastasizing adenocarcinomas of the lung.
Adenocarcinoma
Genes of laminin B1 chain, alpha 1 (IV) chain of type IV collagen, and 72-kd type IV collagenase are mainly expressed by the stromal cells of lung carcinomas.
Adenocarcinoma
High serum TIMP-1 is associated with adverse prognosis in endometrial carcinoma.
Adenocarcinoma
Hypoxia augments gelatinase activity in a variety of adenocarcinomas in vitro.
Adenocarcinoma
Hypoxia induces oncogene yes-associated protein 1 nuclear translocation to promote pancreatic ductal adenocarcinoma invasion via epithelial-mesenchymal transition.
Adenocarcinoma
Immunocytochemical detection of the expression of members of the matrix metalloproteinase family in adenocarcinomas of the pancreas.
Adenocarcinoma
Immunoelectron microscopic localization of gelatinase A in human gastrointestinal and skin carcinomas: difference between cancer cells and fibroblasts.
Adenocarcinoma
Immunohistochemical analysis of type IV collagenase expression in prostatic hyperplasia and adenocarcinoma.
Adenocarcinoma
Immunohistochemical evaluation of type IV collagenase (72-kd metalloproteinase) in prostatic intraepithelial neoplasia.
Adenocarcinoma
Increased expression of matrix metalloproteinase-2 (MMP-2) predicts tumour recurrence and unfavourable outcome in non-small cell lung cancer.
Adenocarcinoma
Increased expression of the 72-kd type IV collagenase in prostatic adenocarcinoma. Demonstration by immunohistochemistry and in situ hybridization.
Adenocarcinoma
Increased expression of the Mr 72,000 type IV collagenase in human colonic adenocarcinoma.
Adenocarcinoma
Inhibition by retinoic acid of type IV collagenolysis and invasion through reconstituted basement membrane by metastatic rat mammary adenocarcinoma cells.
Adenocarcinoma
Inhibitory effect of acetylsalicylic acid on metalloproteinase activity in human lung adenocarcinoma at different stages of differentiation.
Adenocarcinoma
Intrabronchial orthotopic propagation of human lung adenocarcinoma--characterizations of tumorigenicity, invasion and metastasis.
Adenocarcinoma
Localization of the 92 kd gelatinase mRNA in squamous cell and adenocarcinomas of the lung using in situ hybridization.
Adenocarcinoma
Location of 72-kd metalloproteinase (type IV collagenase) in untreated prostatic adenocarcinoma.
Adenocarcinoma
Marked induction of gelatinases, especially type B, in host fibroblasts by human ovarian cancer cells in athymic mice.
Adenocarcinoma
Matrix metalloproteinase inhibitor RO 28-2653 decreases liver metastasis by reduction of MMP-2 and MMP-9 concentration in BOP-induced ductal pancreatic cancer in Syrian Hamsters: inhibition of matrix metalloproteinases in pancreatic cancer.
Adenocarcinoma
Matrix metalloproteinase-2 (MMP-2) and -9 (MMP-9) in preoperative serum as independent prognostic markers in patients with colorectal cancer.
Adenocarcinoma
Matrix metalloproteinase-2 (MMP-2) is associated with survival in breast carcinoma.
Adenocarcinoma
Matrix metalloproteinase-2 gene polymorphism is not associated with increased glioblastoma multiforme susceptibility: an Indian institutional experience.
Adenocarcinoma
Matrix metalloproteinase-2 status in stromal fibroblasts, not in tumor cells, is a significant prognostic factor in non-small-cell lung cancer.
Adenocarcinoma
Matrix metalloproteinase-triggered denuding of engineered gold nanoparticles for selective cell uptake.
Adenocarcinoma
Matrix metalloproteinases 2 and 9 in situ mRNA expression in colorectal tumors from Iraqi patients.
Adenocarcinoma
Matrix metalloproteinases and tissue inhibitors of metalloproteinases in colonic adenomas-adenocarcinomas.
Adenocarcinoma
Metalloproteinases and tissue inhibitor of metalloproteinase 1 (TIMP-1) in endometrial flushings from pre- and post-menopausal women and from women with endometrial adenocarcinoma.
Adenocarcinoma
Metastasis-associated alterations in phospholipids and fatty acids of human prostatic adenocarcinoma cell lines.
Adenocarcinoma
MMP-13 In-Vivo Molecular Imaging Reveals Early Expression in Lung Adenocarcinoma.
Adenocarcinoma
MMP-2 activation and stepwise progression of pulmonary adenocarcinoma: analysis of MMP-2 and MMP-9 with gelatin zymography.
Adenocarcinoma
Modulation of monocyte matrix metalloproteinase-2 by breast adenocarcinoma cells.
Adenocarcinoma
MT1-MMP and MMP-2 mRNA expression in human ovarian tumors: possible implications for the role of desmoplastic fibroblasts.
Adenocarcinoma
MT1-MMP expression promotes tumor growth and angiogenesis through an up-regulation of vascular endothelial growth factor expression.
Adenocarcinoma
Nrf2-peroxiredoxin I axis in polymorphous adenocarcinoma is associated with low matrix metalloproteinase 2 level.
Adenocarcinoma
Osteopontin is linked to p65 and MMP-9 expression in pulmonary adenocarcinoma but not in malignant pleural mesothelioma.
Adenocarcinoma
Ovarian carcinoma cells in serous effusions show altered MMP-2 and TIMP-2 mRNA levels.
Adenocarcinoma
Overexpression of matrix metalloproteinase-2 and tissue inhibitor of matrix metalloproteinase-2 in liver from patients with gastrointestinal adenocarcinoma and no detectable metastasis.
Adenocarcinoma
Preliminary evaluation for Bit1 as a potential biomarker for squamous cell carcinoma and adenocarcinoma of esophagus.
Adenocarcinoma
Prognostic significance of stromal metalloproteinase-2 in ovarian adenocarcinoma and its relation to carcinoma progression.
Adenocarcinoma
Recombinant viral protein promotes apoptosis and suppresses invasion of ovarian adenocarcinoma cells by targeting ?5?1 integrin to downregulate Akt and MMP-2.
Adenocarcinoma
Serum and plasma M(r) 92,000 progelatinase levels correlate with spontaneous metastasis of rat 13762NF mammary adenocarcinoma.
Adenocarcinoma
SKOV-3 cell imaging by paramagnetic particles labeled with hairpin cell-penetrating peptides.
Adenocarcinoma
Small adenocarcinoma of the lung: prognostic significance of central fibrosis chiefly because of its association with angiogenesis and lymphangiogenesis.
Adenocarcinoma
Soybean Bowman-Birk Protease Inhibitor (BBI): Identification of the Mechanisms of BBI Suppressive Effect on Growth of Two Adenocarcinoma Cell Lines: AGS and HT29.
Adenocarcinoma
Suppression of prostate cancer invasive potential and matrix metalloproteinase activity by E-cadherin transfection.
Adenocarcinoma
Tamoxifen exerts oestrogen-agonistic effects on proliferation and plasminogen activation, but not on gelatinase activity, glycogen metabolism and p53 protein expression, in cultures of oestrogen-responsive human endometrial adenocarcinoma cells.
Adenocarcinoma
The ?-adrenoceptor antagonist, propranolol, induces human gastric cancer cell apoptosis and cell cycle arrest via inhibiting nuclear factor ?B signaling.
Adenocarcinoma
The association of transforming growth factor-beta 1 with myometrial invasion of endometrial carcinomas through effects on matrix metalloproteinase.
Adenocarcinoma
The expression of matrix metalloproteinases in intrahepatic cholangiocarcinoma, hilar (Klatskin tumor), middle and distal extrahepatic cholangiocarcinoma, gallbladder cancer, and ampullary carcinoma: role of matrix metalloproteinases in tumor progression and prognosis.
Adenocarcinoma
The expression of matrix metalloproteinases-2 and -9 and their tissue inhibitor 2 in pancreatic ductal and ampullary carcinoma and their relation to angiogenesis and clinicopathological parameters.
Adenocarcinoma
The expression of MMP-2 and TIMP-2 in patients with colorectal adenocarcinoma invaded to the submucosal and proper muscle layer.
Adenocarcinoma
The expression of MMP-2 and TIMP-2 in patients with primary colorectal adenocarcinoma: correlation with liver metastasis.
Adenocarcinoma
The Immunohistochemical Expression of STAT3, Bcl-xL, and MMP-2 Proteins in Colon Adenoma and Adenocarcinoma.
Adenocarcinoma
The role of inflammation in patients with intraductal mucinous neoplasm of the pancreas and in those with pancreatic adenocarcinoma.
Adenocarcinoma
Tumor cell surface-associated binding site for the M(r) 72,000 type IV collagenase.
Adenocarcinoma
[Expression and clinical significance of CD147 and MMP-2 ?in squamous cell carcinoma and adenocarcinoma of the lungs].
Adenocarcinoma
[Expression and clinicopathologic significance of OPN, CD44v6 and MMP-2 in squamous cell carcinoma and adenocarcinoma of the lung].
Adenocarcinoma
[Expression of matrix metalloproteinase-2, 9 and it's tissue inhibitor-1, 2 in endometrial carcinoma]
Adenocarcinoma
[Expression of matrix metaloproteinase and tissue inhibitors in ovarian tumors]
Adenocarcinoma
[Expression of MMP-2 and MMP-9 in non-small-cell lung cancer and their prognostic value.]
Adenocarcinoma
[New direct assay method of type IV collagenase in tissue homogenate and biochemical role of collagenase against type I, and IV collagens to the invasion of the stomach and lung cancer]
Adenocarcinoma
[Prognostic value of stromal immunolabelling by MMP-2, MT1-MMP and TIMP-2 in clinically localized prostate cancer]
Adenocarcinoma of Lung
Alpha-mangostin suppresses phorbol 12-myristate 13-acetate-induced MMP-2/MMP-9 expressions via alphavbeta3 integrin/FAK/ERK and NF-kappaB signaling pathway in human lung adenocarcinoma A549 cells.
Adenocarcinoma of Lung
Basement membrane patterns, gelatinase A and tissue inhibitor of metalloproteinase-2 expressions, and stromal fibrosis during the development of peripheral lung adenocarcinoma.
Adenocarcinoma of Lung
Cellular localization of EMMPRIN predicts prognosis of patients with operable lung adenocarcinoma independent from MMP-2 and MMP-9.
Adenocarcinoma of Lung
Computed tomographic images reflect the biologic behavior of small lung adenocarcinoma: they correlate with cell proliferation, microvascularization, cell adhesion, degradation of extracellular matrix, and K-ras mutation.
Adenocarcinoma of Lung
Depsipeptide a histone deacetlyase inhibitor down regulates levels of matrix metalloproteinases 2 and 9 mRNA and protein expressions in lung cancer cells (A549).
Adenocarcinoma of Lung
Differential expression of membrane-type matrix metalloproteinase and its correlation with gelatinase A activation in human malignant brain tumors in vivo and in vitro.
Adenocarcinoma of Lung
GABRA3 promotes lymphatic metastasis in lung adenocarcinoma by mediating upregulation of matrix metalloproteinases.
Adenocarcinoma of Lung
Gelatinase activity of matrix metalloproteinases during first-line chemotherapy in lung adenocarcinoma patients: an initial approach.
Adenocarcinoma of Lung
Granulocyte, granulocyte-macrophage, and macrophage colony-stimulating factors can stimulate the invasive capacity of human lung cancer cells.
Adenocarcinoma of Lung
Growth pattern correlates with the distribution of basement membrane and prognosis in lung adenocarcinoma.
Adenocarcinoma of Lung
HoxB7 PROMOTES GROWTH AND METASTASIS OF LUNG ADENOCARCINOMA CELLS THROUGH REGULATION OF THE TGF-?/SMAD3 SIGNALING.
Adenocarcinoma of Lung
Human papillomavirus up-regulates MMP-2 and MMP-9 expression and activity by inducing interleukin-8 in lung adenocarcinomas.
Adenocarcinoma of Lung
Inhibitory effect of acetylsalicylic acid on metalloproteinase activity in human lung adenocarcinoma at different stages of differentiation.
Adenocarcinoma of Lung
Intrabronchial orthotopic propagation of human lung adenocarcinoma--characterizations of tumorigenicity, invasion and metastasis.
Adenocarcinoma of Lung
Invasion and metastasis: the expression and significance of matrix metalloproteinases in carcinomas of the lung.
Adenocarcinoma of Lung
MMP-2 siRNA induced Fas/CD95-mediated extrinsic II apoptotic pathway in the A549 lung adenocarcinoma cell line.
Adenocarcinoma of Lung
N-myc downstream regulated gene 2 overexpression reduces matrix metalloproteinase-2 and -9 activities and cell invasion of A549 lung cancer cell line in vitro.
Adenocarcinoma of Lung
Novel ternary vanadium-betaine-peroxido species suppresses H-ras and matrix metalloproteinase-2 expression by increasing reactive oxygen species-mediated apoptosis in cancer cells.
Adenocarcinoma of Lung
POU5F1 enhances the invasiveness of cancer stem-like cells in lung adenocarcinoma by upregulation of MMP-2 expression.
Adenocarcinoma of Lung
Resveratrol analog-3,5,4'-trimethoxy-trans-stilbene inhibits invasion of human lung adenocarcinoma cells by suppressing the MAPK pathway and decreasing matrix metalloproteinase-2 expression.
Adenocarcinoma of Lung
Silencing of LINC00461 enhances radiosensitivity of lung adenocarcinoma cells by down-regulating HOXA10 via microRNA-195.
Adenocarcinoma of Lung
Suppression of cell invasion and migration by propofol are involved in down-regulating matrix metalloproteinase-2 and p38 MAPK signaling in A549 human lung adenocarcinoma epithelial cells.
Adenocarcinoma of Lung
Suppression on metastasis by rhubarb through modulation on MMP-2 and uPA in human A549 lung adenocarcinoma: An ex vivo approach.
Adenocarcinoma of Lung
ZO-2 Suppresses Cell Migration Mediated by a Reduction in Matrix Metalloproteinase 2 in Claudin-18-Expressing Lung Adenocarcinoma A549 Cells.
Adenocarcinoma of Lung
[Anti-sense nucleic acid of CyclinD1 induces apoptosis of lung adenocarcinoma cancer cell A549.]
Adenocarcinoma of Lung
[Effects of Cullin1 on the Biological Characteristics of Lung Adenocarcinoma?A549 and H1395 Cells].
Adenocarcinoma, Bronchiolo-Alveolar
Basement membrane patterns, gelatinase A and tissue inhibitor of metalloproteinase-2 expressions, and stromal fibrosis during the development of peripheral lung adenocarcinoma.
Adenocarcinoma, Bronchiolo-Alveolar
Expression of matrix metalloproteinase (gelatinase) in T1 adenocarcinoma of the lung.
Adenocarcinoma, Follicular
Increased plasminogen activator and type IV collagenase activity in invasive follicular thyroid carcinoma cells.
Adenocarcinoma, Follicular
Perfluorooctanoic Acid Enhances Invasion of Follicular Thyroid Carcinoma Cells Through NF-?B and Matrix Metalloproteinase-2 Activation.
Adenoma
Active matrix metalloproteinase-2 activity discriminates colonic mucosa, adenomas with and without high-grade dysplasia, and cancers.
Adenoma
Analyses of matrix metalloproteinases and their inhibitors in cyst fluid of serous ovarian tumors.
Adenoma
Cardiac Dysfunction in Association with Increased Inflammatory Markers in Primary Aldosteronism.
Adenoma
Contributory role of 5-lipoxygenase and its association with angiogenesis in the promotion of inflammation-associated colonic tumorigenesis by cigarette smoking.
Adenoma
Effect of epithelial growth factor on matrix metalloproteinase-2 and E-cadherin/?-catenin expression in an in situ model of tumorigenesis.
Adenoma
Enhanced production and activation of progelatinase A mediated by membrane-type 1 matrix metalloproteinase in human papillary thyroid carcinomas.
Adenoma
Expression of matrix metalloproteinases (MMP-2, MMP-9, MT1-MMP) and their inhibitors (TIMP-1, TIMP-2) in common epithelial tumors of the ovary.
Adenoma
Expression of matrix metalloproteinases and related tissue inhibitors in the cyst fluids of ovarian mucinous neoplasms.
Adenoma
Expression of matrix metalloproteinases in benign and malignant follicular thyroid lesions.
Adenoma
Expression of matrix metalloproteinases MMP-2, MMP-9 and their tissue inhibitors TIMP-1, -2, and -3 in benign and malignant tumours of the salivary gland.
Adenoma
Expression of serine proteases and metalloproteinases in human pituitary adenomas and anterior pituitary lobe tissue.
Adenoma
Gelatinase A and membrane-type 1 matrix metalloproteinase mRNA: expressed in adrenocortical cancers but not in adenomas.
Adenoma
Increased expression of the Mr 72,000 type IV collagenase in human colonic adenocarcinoma.
Adenoma
Increased matrix metalloproteinase 2 concentration and transcript expression in advanced colorectal carcinomas.
Adenoma
Matrix metalloprotease 2 (MMP-2) and matrix metalloprotease 9 (MMP-9) type IV collagenases in colorectal cancer.
Adenoma
Matrix metalloproteinase 2 and tissue inhibitor of matrix metalloproteinases 2 in the diagnosis of colorectal adenoma and cancer patients.
Adenoma
Matrix metalloproteinase-2 expression correlates with cavernous sinus invasion in pituitary adenomas.
Adenoma
Matrix metalloproteinases and tissue inhibitors of metalloproteinases in colonic adenomas-adenocarcinomas.
Adenoma
Stromal expression of 72 kda type IV collagenase (MMP-2) and TIMP-2 mRNAs in colorectal neoplasia.
Adenoma
Stromal fibroblasts adjacent to invasive thyroid tumors: expression of gelatinase A but not stromelysin 3 mRNA.
Adenoma
The behavior of MMP-2, MMP-7, MMP-9 and their inhibitors TIMP-1, TIMP-2 in adenoma-colorectal cancer sequence.
Adenoma
The Immunohistochemical Expression of STAT3, Bcl-xL, and MMP-2 Proteins in Colon Adenoma and Adenocarcinoma.
Adenoma
Type IV collagen, type IV collagenase activity and ability of cell proliferation in human thyroid tumours.
Adenoma
Type IV collagenase activity and cavernous sinus invasion in human pituitary adenomas.
Adenoma
Type IV collagenase and immunostaining of type IV collagen in human thyroid tumors.
Adenoma
[Relationship of the disturbed balance between matrix metalloproteinases and their tissue inhibitors and the invasion of malignant salivary gland tumours]
Adenoma
[Role of matrix metalloproteinases-9, 2 and their inhibitor-TIMP-1, 2 in invasive pituitary adenomas biological behavior]
Adenoma, Oxyphilic
Matrix metalloproteinase-2 and -9 and tissue inhibitor of metalloproteinase-1 and -2 in sera and urine of patients with renal carcinoma.
Adenoma, Oxyphilic
Matrix metalloproteinase-2 and -9 in the sera and in the urine of human oncocytoma and renal cell carcinoma.
Adenoma, Pleomorphic
Effect of epithelial growth factor on matrix metalloproteinase-2 and E-cadherin/?-catenin expression in an in situ model of tumorigenesis.
Adenoma, Pleomorphic
Expression of matrix metalloproteinases MMP-2, MMP-9 and their tissue inhibitors TIMP-1 and TIMP-2 in the epithelium and stroma of salivary gland pleomorphic adenomas.
Adenoma, Pleomorphic
[The expression of matrix metalloproteinases and their tissue inhibitors in pleomorphic adenoma]
Adenoma, Villous
Matrix metalloproteinases and tissue inhibitors of metalloproteinases in colonic adenomas-adenocarcinomas.
Adenomatous Polyps
Clinicopathologic and Prognostic Significance of Gelatinase A in Tunisian Colorectal Cancer: A Case-Control Study.
Adenomatous Polyps
Enhanced expression of MMP-7 and MMP-13 in inflammatory bowel disease: a precancerous potential?
Adenomatous Polyps
Use of plasma MMP-2 and MMP-9 levels as a surrogate for tumour expression in colorectal cancer patients.
Adenomyoma
[The expression of moesin, p21-activated kinase 4 (PAK 4), matrix metalloproteinases (MMP 2, MMP 9), and CD34 in the eutopic and ectopic endometrium in adenomyosis].
Adenomyosis
Differential immunohistochemical expression of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in cow uteri with adenomyosis during follicular phase.
Adenomyosis
Effect of matrix metalloproteinase promoter polymorphisms on endometriosis and adenomyosis risk: evidence from a meta-analysis.
Adenomyosis
Expression of Cyclooxygenase-2 and Matrix Metalloproteinase-2 in Adenomyosis and Endometrial Polyps and its Correlation With Angiogenesis.
Adenomyosis
Increased expression of p21-activated kinase 4 in adenomyosis and its regulation of matrix metalloproteinase-2 and -9 in endometrial cells.
Adenomyosis
Increased invasion activity of endometrial stromal cells and elevated expression of matrix metalloproteinase messenger RNA in the uterine tissues of mice with experimentally induced adenomyosis.
Adenomyosis
Increased matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-1 secretion but unaffected invasiveness of endometrial stromal cells in adenomyosis.
Adenomyosis
Matrix Metalloproteinase-2 and -9 Expression Correlated with Angiogenesis in Human Adenomyosis.
Adenomyosis
Polymorphisms in the matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 and the risk of human adenomyosis.
Adenomyosis
[Expression of matrix metalloproteinase and tissue inhibitor of metalloproteinase in adenomyosis]
Adenomyosis
[Study on the association of SNPs of MMP-2 and TIMP-2 genes with the risk of endometriosis and adenomyosis]
Adenomyosis
[The expression of moesin, p21-activated kinase 4 (PAK 4), matrix metalloproteinases (MMP 2, MMP 9), and CD34 in the eutopic and ectopic endometrium in adenomyosis].
Adrenal Cortex Neoplasms
Gelatinase A and membrane-type 1 matrix metalloproteinase mRNA: expressed in adrenocortical cancers but not in adenomas.
Aggressive Periodontitis
Human neutrophil gelatinase and associated lipocalin in adult and localized juvenile periodontitis.
Aggressive Periodontitis
Identification of polymorphonuclear leukocyte collagenase and gelatinase activities in mouthrinse samples: correlation with periodontal disease activity in adult and juvenile periodontitis.
Aggressive Periodontitis
Matrix metalloproteinase-2, -9, and -12 gene polymorphisms in generalized aggressive periodontitis.
Aggressive Periodontitis
Matrix metalloproteinase-2, -9, and tissue inhibitor of MMP-2 gene polymorphisms in Taiwanese periodontitis patients.
Aggressive Periodontitis
MMP-2, MMP-9 and TIMP-2 gene polymorphisms in Chinese patients with generalized aggressive periodontitis.
Aggressive Periodontitis
Multiple forms of gelatinases/type IV collagenases in saliva and gingival crevicular fluid of periodontitis patients.
AIDS Dementia Complex
Cerebrospinal fluid levels of MMP-2, 7, and 9 are elevated in association with human immunodeficiency virus dementia.
Airway Obstruction
Induced sputum metalloproteinases and their inhibitors in relation to exhaled nitrogen oxide and sputum nitric oxides and other inflammatory cytokines in patients with chronic obstructive pulmonary disease.
Airway Obstruction
[Expressions of cyclooxygenase-2 and matrix metalloproteinase-2 and airflow obstruction in patients with chronic obstructive pulmonary disease]
Albuminuria
Absence of Gelatinase (MMP-9) or Collagenase (MMP-13) Attenuates Adriamycin-Induced Albuminuria and Glomerulosclerosis.
Albuminuria
Aldosterone induces albuminuria via matrix metalloproteinase-dependent damage of the endothelial glycocalyx.
Albuminuria
Association of the cystatin C/creatinine ratio with the renally cleared hormones parathyroid hormone (PTH) and brain natriuretic peptide (BNP) in primary care patients: a cross-sectional study.
Albuminuria
Blocking matrix metalloproteinase-mediated syndecan-4 shedding restores the endothelial glycocalyx and glomerular filtration barrier function in early diabetic kidney disease.
Albuminuria
Markers of Glomerular and Tubular Damage in the Early Stage of Kidney Disease in Type 2 Diabetic Patients.
Albuminuria
Plasma levels of matrix metalloproteinase-2, -3, -10, and tissue inhibitor of metalloproteinase-1 are associated with vascular complications in patients with type 1 diabetes: the EURODIAB Prospective Complications Study.
Albuminuria
Ramipril inhibits AGE-RAGE-induced matrix metalloproteinase-2 activation in experimental diabetic nephropathy.
Albuminuria
Role of matrix metalloproteinase-9 in chronic kidney disease: a new biomarker of resistant albuminuria.
Albuminuria
The association between methylation levels of targeted genes and albuminuria in patients with early diabetic kidney disease.
Albuminuria
Urinary matrix metalloproteinase activities: biomarkers for plaque angiogenesis and nephropathy in diabetes.
Albuminuria
Urinary matrix metalloproteinase-8 and -9 activities in type 2 diabetic subjects: A marker of incipient diabetic nephropathy?
Alveolar Bone Loss
A combination of a chemically modified doxycycline and a bisphosphonate synergistically inhibits endotoxin-induced periodontal breakdown in rats.
Alveolar Bone Loss
Atorvastatin decreases bone loss, inflammation and oxidative stress in experimental periodontitis.
Alveolar Bone Loss
Chemically-Modified Curcumin 2.24: A Novel Systemic Therapy for Natural Periodontitis in Dogs.
Alveolar Bone Loss
Effects of formaldehyde on VEGF, MMP2, and Osteonectin levels in periodontal membrane and alveolar bone in the rats.
Alveolar Bone Loss
Gelatinases and extracellular matrix metalloproteinase inducer are associated with cyclosporin-A-induced attenuation of periodontal degradation in rats.
Alzheimer Disease
Activated isoforms of MMP-2 are induced in U87 human glioma cells in response to beta-amyloid peptide.
Alzheimer Disease
Concentrations of Matrix Metalloproteinases and their Tissue Inhibitors in the Cerebrospinal Fluid of Patients with Alzheimer's Disease.
Alzheimer Disease
Design and synthesis of selective and blood-brain barrier-permeable hydroxamate-based gelatinase inhibitors.
Alzheimer Disease
Engineering autoactivating forms of matrix metalloproteinase-9 and expression of the active enzyme in cultured cells and transgenic mouse brain.
Alzheimer Disease
Gelatinase A possesses a beta-secretase-like activity in cleaving the amyloid protein precursor of Alzheimer's disease.
Alzheimer Disease
Investigation of Matrix Metalloproteinases, MMP-2 and MMP-9, in Plasma Reveals a Decrease of MMP-2 in Alzheimer's Disease.
Alzheimer Disease
Matrix Metalloproteinases Are Associated With Increased Blood-Brain Barrier Opening in Vascular Cognitive Impairment.
Alzheimer Disease
Matrix metalloproteinases contribute to neuronal dysfunction in animal models of drug dependence, Alzheimer's disease, and epilepsy.
Alzheimer Disease
MMP-2, -3 and -9 levels and activity are not related to Abeta load in the frontal cortex in Alzheimer's disease.
Alzheimer Disease
Natural Marine and Terrestrial Compounds as Modulators of Matrix Metalloproteinases-2 (MMP-2) and MMP-9 in Alzheimer's Disease.
Alzheimer Disease
Proteolysis of A beta peptide from Alzheimer disease brain by gelatinase A.
Alzheimer Disease
Selective localization of gelatinase A, an enzyme degrading beta-amyloid protein, in white matter microglia and in Schwann cells.
Ameloblastoma
Ameloblastic neoplasia spectrum: a cross-sectional study of MMPS expression and proliferative activity.
Ameloblastoma
Comparison of osteoclastogenesis and local invasiveness of ameloblastoma and keratocystic odontogenic tumor.
Ameloblastoma
Discrimination of ameloblastomas from odontogenic keratocysts by cytokine levels and gelatinase species of the intracystic fluids.
Ameloblastoma
Elevated hydrostatic pressure promotes ameloblastoma cell invasion through upregulation of MMP-2 and MMP-9 expression via Wnt/?-catenin signalling.
Ameloblastoma
Epigenetic regulation of matrix metalloproteinase expression in ameloblastoma.
Ameloblastoma
Expression and role of metalloproteinase-2 and endogenous tissue regulator in ameloblastoma.
Ameloblastoma
Expression of osteonectin/secreted protein acidic and rich in cysteine and matrix metalloproteinases in ameloblastoma.
Ameloblastoma
Immunoexpression of MMPs-1, -2, and -9 in ameloblastoma and odontogenic adenomatoid tumor.
Ameloblastoma
Immunohistochemical detection of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) in ameloblastomas.
Ameloblastoma
Inhibition of ameloblastoma invasion in vitro and in vivo by inhibitor of metalloproteinase-2 activity.
Ameloblastoma
Presence of Myofibroblasts and Expression of Matrix Metalloproteinase-2 (MMP-2) in Ameloblastomas Correlate with Rupture of the Osseous Cortical.
Ameloblastoma
Relative expression of ?-smooth muscle actin and matrix metalloproteinases-2 in ameloblastoma of a black African sub-population.
Ameloblastoma
Suppression of local invasion of ameloblastoma by inhibition of matrix metalloproteinase-2 in vitro.
Ameloblastoma
Tissue inhibitor of metalloproteinase-2 inhibits ameloblastoma growth in a new mouse xenograft disease model.
Ameloblastoma
[Association of matrix metalloproteinase-2 activity with cell proliferation and growth in ameloblastoma]
Amyloidosis
Doxycycline decreases amyloidogenic light chain-induced autophagy in isolated primary cardiac myocytes.
Amyloidosis
Neutrophil gelatinase levels in plasma and synovial fluid of patients with rheumatic diseases.
Amyotrophic Lateral Sclerosis
Engineering autoactivating forms of matrix metalloproteinase-9 and expression of the active enzyme in cultured cells and transgenic mouse brain.
Amyotrophic Lateral Sclerosis
Selective localization of gelatinase A, an enzyme degrading beta-amyloid protein, in white matter microglia and in Schwann cells.
Amyotrophic Lateral Sclerosis
Serum levels of matrix metalloproteinases: implications in clinical neurology.
Anaplasia
High levels of messenger RNAs for tissue inhibitors of metalloproteinases (TIMP-1 and TIMP-2) in primary breast carcinomas are associated with development of distant metastases.
Aneurysm
A potential key mechanism in ascending aortic aneurysm development: Detection of a linear relationship between MMP-14/TIMP-2 ratio and active MMP-2.
Aneurysm
A reproducible swine model of a surgically created saccular thoracic aortic aneurysm.
Aneurysm
Activation of Endocannabinoid System Is Associated with Persistent Inflammation in Human Aortic Aneurysm.
Aneurysm
Arterial wall degeneration plus hemodynamic insult cause arterial wall remodeling and nascent aneurysm formation at specific sites in dogs.
Aneurysm
ATP stimulates MMP-2 release from human aortic smooth muscle cells via JNK signaling pathway.
Aneurysm
Bazedoxifene, a selective estrogen receptor modulator, reduces cerebral aneurysm rupture in Ovariectomized rats.
Aneurysm
Chemokines induce matrix metalloproteinase-2 through activation of epidermal growth factor receptor in arterial smooth muscle cells.
Aneurysm
Combining two potential causes of metalloproteinase secretion causes abdominal aortic aneurysms in rats: a new experimental model.
Aneurysm
Early Increased MT1-MMP Expression and Late MMP-2 and MMP-9 Activity during Angiotensin II Induced Aneurysm Formation.
Aneurysm
Effects of deletion of the tissue inhibitor of matrix metalloproteinases-1 gene on the progression of murine thoracic aortic aneurysms.
Aneurysm
Erythropoietin increases circulating endothelial progenitor cells and reduces the formation and progression of cerebral aneurysm in rats.
Aneurysm
Expression of matrix metalloproteinases and their inhibitors in aneurysms and normal aorta.
Aneurysm
Expression of MMP-2, MMP-9, and NGAL in Tissue and Serum of Patients with Vascular Aneurysms and Their Modulation by Statin Treatment: A Pilot Study.
Aneurysm
Genetic kininogen deficiency contributes to aortic aneurysm formation but not to atherosclerosis.
Aneurysm
Heterogeneity of tensile strength and matrix metalloproteinase activity in the wall of abdominal aortic aneurysms.
Aneurysm
Identification of a serum gelatinase associated with the occurrence of cerebral aneurysms as pro-matrix metalloproteinase-2.
Aneurysm
In situ localization and quantification of seventy-two-kilodalton type IV collagenase in aneurysmal, occlusive, and normal aorta.
Aneurysm
Increased matrix metalloproteinase 2 expression in vascular smooth muscle cells cultured from abdominal aortic aneurysms.
Aneurysm
Increased PAI-1 in Females Compared to Males is Protective for Abdominal Aortic Aneurysm Formation in a Rodent Model.
Aneurysm
Inflammation and matrix metalloproteinases in the enlarging abdominal aortic aneurysm.
Aneurysm
Influence of elastin-derived peptides on metalloprotease production in endothelial cells.
Aneurysm
Interference of doxycycline pretreatment in a model of abdominal aortic aneurysms.
Aneurysm
Localization of matrix metalloproteinase 2 within the aneurysmal and normal aortic wall.
Aneurysm
Marimastat inhibits elastin degradation and matrix metalloproteinase 2 activity in a model of aneurysm disease.
Aneurysm
Matrix metalloproteinase activity in thoracic aortic aneurysms associated with bicuspid and tricuspid aortic valves.
Aneurysm
Matrix metalloproteinase and tissue inhibitor expression in atherosclerotic and nonatherosclerotic thoracic aortic aneurysms.
Aneurysm
Matrix metalloproteinases 2 and 9 in human atherosclerotic and non-atherosclerotic cerebral aneurysms.
Aneurysm
Matrix metalloproteinases and tissue inhibitors of metalloproteinases expression in human cerebral ruptured and unruptured aneurysm.
Aneurysm
Matrix metalloproteinases in ascending aortic aneurysms: bicuspid versus trileaflet aortic valves.
Aneurysm
Matrix metalloproteinases in the aneurysm wall of patients treated with low-dose doxycycline.
Aneurysm
Matrix metalloproteinases synthesized in autosomal dominant polycystic kidney disease play a role in development of a concurrent abdominal aortic aneurysm.
Aneurysm
Mechanism of inhibition of matrix metalloproteinase-2 expression by doxycycline in human aortic smooth muscle cells.
Aneurysm
MMP inhibition in abdominal aortic aneurysms. Rationale for a prospective randomized clinical trial.
Aneurysm
MMP-2 Isoforms in Aortic Tissue and Serum of Patients with Ascending Aortic Aneurysms and Aortic Root Aneurysms.
Aneurysm
MR imaging of iron phagocytosis in intraluminal thrombi of abdominal aortic aneurysms in humans.
Aneurysm
Phyto-Derived Products as Matrix Metalloproteinases Inhibitors in Cardiovascular Diseases.
Aneurysm
Plasma matrix metalloproteinase levels do not predict tissue levels in abdominal aortic aneurysms suitable for elective repair.
Aneurysm
Presence of Chlamydia pneumoniae in abdominal aortic aneurysms is not associated with increased activity of matrix metalloproteinases.
Aneurysm
Recombinant Interleukin-19 Suppresses the Formation and Progression of Experimental Abdominal Aortic Aneurysms.
Aneurysm
Role of estrogen deficiency in the formation and progression of cerebral aneurysms. Part I: experimental study of the effect of oophorectomy in rats.
Aneurysm
Role of matrix metalloproteinases (MMPs) and MMP inhibitors on intracranial aneurysms: a review article.
Aneurysm
SDF-1?/CXCR4 Pathway Mediates Hemodynamics-Induced Formation of Intracranial Aneurysm by Modulating the Phenotypic Transformation of Vascular Smooth Muscle Cells.
Aneurysm
Serum MMP-2 and MMP-9 in patients with Behçet's disease: Do their higher levels correlate to vasculo-Behçet's disease associated with aneurysm formation?
Aneurysm
Systemic Administration of Ribbon-type Decoy Oligodeoxynucleotide Against Nuclear Factor ?B and Ets Prevents Abdominal Aortic Aneurysm in Rat Model.
Aneurysm
The 5-lipoxygenase pathway promotes pathogenesis of hyperlipidemia-dependent aortic aneurysm.
Aneurysm
The expression and localization of membrane type-1 matrix metalloproteinase in human abdominal aortic aneurysms.
Aneurysm
The protective effect of puerarin on angiotensin II-induced aortic aneurysm formation by the inhibition of NADPH oxidase activation and oxidative stress-triggered AP-1 signaling pathways.
Aneurysm
Time-dependent and site-dependent morphological changes in rupture-prone arteries: ovariectomized rat intracranial aneurysm model.
Aneurysm
Ubiquitous elevation of matrix metalloproteinase-2 expression in the vasculature of patients with abdominal aneurysms.
Aneurysm, Dissecting
Ang II enhances noradrenaline release from sympathetic nerve endings thus contributing to the up-regulation of metalloprotease-2 in aortic dissection patients' aorta wall.
Aneurysm, Dissecting
Association of MMP-2 gene haplotypes with thoracic aortic dissection in chinese han population.
Aneurysm, Dissecting
Association of smooth muscle cell phenotypes with extracellular matrix disorders in thoracic aortic dissection.
Aneurysm, Dissecting
Autonomic remodeling may be responsible for decreased incidence of aortic dissection in STZ-induced diabetic rats via down-regulation of matrix metalloprotease 2.
Aneurysm, Dissecting
Increased tissue microarray matrix metalloproteinase expression favors proteolysis in thoracic aortic aneurysms and dissections.
Aneurysm, Dissecting
Local upregulation of interleukin-1 beta in aortic dissecting aneurysm: correlation with matrix metalloproteinase-2, 9 expression and biomechanical decrease.
Aneurysm, Dissecting
MMP-2 gene polymorphisms are associated with type A aortic dissection and aortic diameters in patients.
Aneurysm, Dissecting
Plasma levels of metalloproteinases-9 and -2 in the acute and subacute phases of type A and type B aortic dissection.
Aneurysm, Dissecting
Serum levels of matrix metalloproteinases -1,-2,-3 and -9 in thoracic aortic diseases and acute myocardial ischemia.
Aneurysm, Dissecting
The expression and significance of IL-6, IFN-?, SM22?, and MMP-2 in rat model of aortic dissection.
Aneurysm, Dissecting
The expression of the BRM and MMP2 genes in thoracic aortic aneurysm and aortic dissection.
Aneurysm, Dissecting
The prominent expression of plasma matrix metalloproteinase-8 in acute thoracic aortic dissection.
Aneurysm, Dissecting
Up-regulation of matrix metalloproteinase-2 and membrane-type 1-matrix metalloproteinase were coupled with that of type I procollagen in granulation tissue response after the onset of aortic dissection.
Aneurysm, Dissecting
[Effect of bilateral superior cervical sympathetic ganglion occlusion on pathological process of aortic dissection and its mechanism].
Aneurysm, Ruptured
Activation of Extracellular signal-Related Kinase in abdominal aortic aneurysm.
Aneurysm, Ruptured
Matrix metalloproteinases and tissue inhibitors of metalloproteinases expression in human cerebral ruptured and unruptured aneurysm.
Aneurysm, Ruptured
SDF-1?/CXCR4 Pathway Mediates Hemodynamics-Induced Formation of Intracranial Aneurysm by Modulating the Phenotypic Transformation of Vascular Smooth Muscle Cells.
Angina Pectoris
Enhanced cardiac production of matrix metalloproteinase-2 and -9 and its attenuation associated with pravastatin treatment in patients with acute myocardial infarction.
Angina, Stable
CD100 modulates cytotoxicity of CD8+ T cells in patients with acute myocardial infarction.
Angina, Stable
Correlation between plasma angiopoietin-1, angiopoietin-2 and matrix metalloproteinase-2 in coronary heart disease.
Angina, Stable
Elevated circulating levels of matrix metalloproteinase-9 and -2 in patients with symptomatic coronary artery disease.
Angina, Stable
Expressions and clinical significance of factors related to acute coronary syndrome.
Angina, Stable
Identification of 92-kD gelatinase in human coronary atherosclerotic lesions. Association of active enzyme synthesis with unstable angina.
Angina, Stable
Metalloproteinases-2, -9 and TIMP-1 expression in stable and unstable coronary plaques undergoing PCI.
Angina, Stable
New insights into molecular mechanisms of diffuse coronary ectasiae: a possible role for VEGF.
Angina, Unstable
CD100 modulates cytotoxicity of CD8+ T cells in patients with acute myocardial infarction.
Angina, Unstable
Correlation between plasma angiopoietin-1, angiopoietin-2 and matrix metalloproteinase-2 in coronary heart disease.
Angina, Unstable
Identification of 92-kD gelatinase in human coronary atherosclerotic lesions. Association of active enzyme synthesis with unstable angina.
Angina, Unstable
Serum profiles of matrix metalloproteinases and their tissue inhibitor in patients with acute coronary syndromes. The effects of short-term atorvastatin administration.
Angiofibroma
TGF-beta enhances MMP-2 expression and activity through AKT in fibroblasts derived from angiofibromas in patients with tuberous sclerosis complex.
Ankylosis
An extract from Myracrodruon urundeuva inhibits matrix mineralization in human osteoblasts.
Anthrax
Cytotoxicity of the matrix metalloproteinase-activated anthrax lethal toxin is dependent on gelatinase expression and B-RAF status in human melanoma cells.
Antiphospholipid Syndrome
Higher levels of plasma matrix metalloproteinase-2 are associated with a significantly increased risk of arterial thrombosis in patients with the antiphospholipid syndrome.
Aortic Aneurysm
A potential key mechanism in ascending aortic aneurysm development: Detection of a linear relationship between MMP-14/TIMP-2 ratio and active MMP-2.
Aortic Aneurysm
Amelioration of salvianolic acid C on aortic structure in apolipoprotein E-deficient mice treated with angiotension II.
Aortic Aneurysm
Angiotensin II induces an increase in MMP-2 expression in idiopathic ascending aortic aneurysm via AT1 receptor and JNK pathway.
Aortic Aneurysm
ATP stimulates MMP-2 release from human aortic smooth muscle cells via JNK signaling pathway.
Aortic Aneurysm
Characterization of serum matrix metalloproteinase 2/9 levels in patients with ascending aortic aneurysms.
Aortic Aneurysm
Early MT-1 MMP expression following elastase exposure is associated with increased cleaved MMP-2 activity in experimental rodent aortic aneurysms.
Aortic Aneurysm
Effect of miR-21 on rat thoracic aortic aneurysm model by regulating the expressions of MMP-2 and MMP-9.
Aortic Aneurysm
Elevated messenger RNA expression and plasma protein levels of osteopontin and matrix metalloproteinase types 2 and 9 in patients with ascending aortic aneurysms.
Aortic Aneurysm
Enhanced invasive properties exhibited by smooth muscle cells are associated with elevated production of MMP-2 in patients with aortic aneurysms.
Aortic Aneurysm
In situ localization and quantification of mRNA for 92-kD type IV collagenase and its inhibitor in aneurysmal, occlusive, and normal aorta.
Aortic Aneurysm
In situ localization and quantification of seventy-two-kilodalton type IV collagenase in aneurysmal, occlusive, and normal aorta.
Aortic Aneurysm
Increased tissue microarray matrix metalloproteinase expression favors proteolysis in thoracic aortic aneurysms and dissections.
Aortic Aneurysm
Localization of matrix metalloproteinase 2 within the aneurysmal and normal aortic wall.
Aortic Aneurysm
Matrix Metalloproteinase-2 Isoforms Differ within the Aortic Wall of Ascending Aortic Aneurysms Associated with Bicuspid Aortic Valve.
Aortic Aneurysm
MCP-1, ICAM-1 and VCAM-1 are present in early aneurysmal dilatation in experimental rats.
Aortic Aneurysm
Mechanism of inhibition of matrix metalloproteinase-2 expression by doxycycline in human aortic smooth muscle cells.
Aortic Aneurysm
MMP-2 Isoforms in Aortic Tissue and Serum of Patients with Ascending Aortic Aneurysms and Aortic Root Aneurysms.
Aortic Aneurysm
Smooth muscle NADPH oxidase 4 promotes angiotensin II-induced aortic aneurysm and atherosclerosis by regulating osteopontin.
Aortic Aneurysm
The protective effect of puerarin on angiotensin II-induced aortic aneurysm formation by the inhibition of NADPH oxidase activation and oxidative stress-triggered AP-1 signaling pathways.
Aortic Aneurysm, Abdominal
Activation of Extracellular signal-Related Kinase in abdominal aortic aneurysm.
Aortic Aneurysm, Abdominal
Activity of matrix metalloproteinase-2 and -9 in abdominal aortic aneurysms. Relation to size and rupture.
Aortic Aneurysm, Abdominal
An uncommon case of arterial aneurysms association with high plasma levels of Matrix Metalloproteinase-9 and Neutrophil Gelatinase-Associated Lipocalin.
Aortic Aneurysm, Abdominal
Angiotensin II-accelerated atherosclerosis and aneurysm formation is attenuated in osteopontin-deficient mice.
Aortic Aneurysm, Abdominal
Cellular localization of matrix metalloproteinases in the abdominal aortic aneurysm wall.
Aortic Aneurysm, Abdominal
Decreased tissue inhibitor of metalloproteinase-2/matrix metalloproteinase ratio in the acute phase of aortic dissection.
Aortic Aneurysm, Abdominal
Dipeptidyl peptidase-4 inhibitor decreases abdominal aortic aneurysm formation through GLP-1-dependent monocytic activity in mice.
Aortic Aneurysm, Abdominal
Doxycycline inhibition of aneurysmal degeneration in an elastase-induced rat model of abdominal aortic aneurysm: preservation of aortic elastin associated with suppressed production of 92 kD gelatinase.
Aortic Aneurysm, Abdominal
Early MT-1 MMP expression following elastase exposure is associated with increased cleaved MMP-2 activity in experimental rodent aortic aneurysms.
Aortic Aneurysm, Abdominal
Elevated messenger RNA expression and plasma protein levels of osteopontin and matrix metalloproteinase types 2 and 9 in patients with ascending aortic aneurysms.
Aortic Aneurysm, Abdominal
Evaluation of the levels of metalloproteinsase-2 in patients with abdominal aneurysm and abdominal hernias.
Aortic Aneurysm, Abdominal
Hypoxia in Abdominal Aortic Aneurysm Supports a Role for HIF-1? and Ets-1 as Drivers of Matrix Metalloproteinase Upregulation in Human Aortic Smooth Muscle Cells.
Aortic Aneurysm, Abdominal
Immunohistochemical expression of metalloproteinases MMP-2 and MMP-9 in abdominal aortic aneurysms: correlation with symptoms and aortic diameter.
Aortic Aneurysm, Abdominal
Increased matrix metalloproteinase 2 expression in vascular smooth muscle cells cultured from abdominal aortic aneurysms.
Aortic Aneurysm, Abdominal
Matrix metalloproteinase 2 is suppressed by trapidil, a CD40-CD40 ligand pathway inhibitor, in human abdominal aortic aneurysm wall.
Aortic Aneurysm, Abdominal
Matrix metalloproteinase 2 polymorphisms in a caucasian population with abdominal aortic aneurysm.
Aortic Aneurysm, Abdominal
Matrix metalloproteinase-2 gene variants and abdominal aortic aneurysm.
Aortic Aneurysm, Abdominal
Matrix metalloproteinase-2 production and its binding to the matrix are increased in abdominal aortic aneurysms.
Aortic Aneurysm, Abdominal
Matrix metalloproteinases synthesized in autosomal dominant polycystic kidney disease play a role in development of a concurrent abdominal aortic aneurysm.
Aortic Aneurysm, Abdominal
Neutrophil depletion inhibits experimental abdominal aortic aneurysm formation.
Aortic Aneurysm, Abdominal
Overexpression of TIMP-2 mediated by recombinant adenovirus in rat abdominal aorta inhibits extracellular matrix degradation.
Aortic Aneurysm, Abdominal
Porphyromonas gingivalis promotes murine abdominal aortic aneurysms via matrix metalloproteinase-2 induction.
Aortic Aneurysm, Abdominal
Production and localization of 92-kilodalton gelatinase in abdominal aortic aneurysms. An elastolytic metalloproteinase expressed by aneurysm-infiltrating macrophages.
Aortic Aneurysm, Abdominal
Serum MMP-2 and MMP-9 in patients with Behçet's disease: Do their higher levels correlate to vasculo-Behçet's disease associated with aneurysm formation?
Aortic Aneurysm, Abdominal
Spatial differences of matrix metalloproteinase-2 and matrix metalloproteinase-9 within abdominal aortic aneurysm wall and intraluminal thrombus.
Aortic Aneurysm, Abdominal
Transgenic expression of matrix metalloproteinase-2 induces coronary artery ectasia.
Aortic Aneurysm, Abdominal
[Analysis of tissue inhibitor of metalloproteinase-2 gene polymorphisms in a caucasian population with abdominal aortic aneurysms]
Aortic Aneurysm, Thoracic
A potential key mechanism in ascending aortic aneurysm development: Detection of a linear relationship between MMP-14/TIMP-2 ratio and active MMP-2.
Aortic Aneurysm, Thoracic
Angiotensin II increases matrix metalloproteinase 2 expression in human aortic smooth muscle cells via AT1R and ERK1/2.
Aortic Aneurysm, Thoracic
Angiotensin II Induces an Increase in Matrix Metalloproteinase 2 Expression in Aortic Smooth Muscle Cells of Ascending Thoracic Aortic Aneurysms Through JNK, ERK1/2, and p38 MAPK Activation.
Aortic Aneurysm, Thoracic
Differential expression of MMP-2, MMP-9 and TIMP proteins in thoracic aortic aneurysm - comparison with and without bicuspid aortic valve: a meta-analysis.
Aortic Aneurysm, Thoracic
Divergent Role of Matrix Metalloproteinase 2 in Pathogenesis of Thoracic Aortic Aneurysm.
Aortic Aneurysm, Thoracic
Effect of miR-21 on rat thoracic aortic aneurysm model by regulating the expressions of MMP-2 and MMP-9.
Aortic Aneurysm, Thoracic
Elevation of ADAM10, ADAM17, MMP-2 and MMP-9 expression with media degeneration features CaCl2-induced thoracic aortic aneurysm in a rat model.
Aortic Aneurysm, Thoracic
Long-term doxycycline is more effective than atenolol to prevent thoracic aortic aneurysm in marfan syndrome through the inhibition of matrix metalloproteinase-2 and -9.
Aortic Aneurysm, Thoracic
Loss of elastic fiber integrity and reduction of vascular smooth muscle contraction resulting from the upregulated activities of matrix metalloproteinase-2 and -9 in the thoracic aortic aneurysm in Marfan syndrome.
Aortic Aneurysm, Thoracic
Matrix metalloproteinase activity in thoracic aortic aneurysms associated with bicuspid and tricuspid aortic valves.
Aortic Aneurysm, Thoracic
Temporal disparity in the induction of matrix metalloproteinases and tissue inhibitors of metalloproteinases after thoracic aortic aneurysm formation.
Aortic Aneurysm, Thoracic
The expression of the BRM and MMP2 genes in thoracic aortic aneurysm and aortic dissection.
Aortic Diseases
Matrix metalloproteinases in ascending aortic aneurysms: bicuspid versus trileaflet aortic valves.
Aortic Valve Stenosis
A Possible Early Biomarker for Bicuspid Aortopathy: Circulating Transforming Growth Factor ?-1 to Soluble Endoglin Ratio.
Aortic Valve Stenosis
Alterations in circulating activin A, GDF-15, TGF-beta3 and MMP-2, -3, and -9 during one year of left ventricular reverse remodelling in patients operated for severe aortic stenosis.
Aortic Valve Stenosis
Chemically modified tetracyclines (CMT-3 and CMT-8) enable control of the pathologic remodellation of human aortic valve stenosis via MMP-9 and VEGF inhibition.
Aortic Valve Stenosis
Circulating matrix metalloproteinase patterns in association with aortic dilatation in bicuspid aortic valve patients with isolated severe aortic stenosis.
Aortic Valve Stenosis
Expression and activity of matrix metalloproteinase-2 in calcific aortic stenosis.
Aortic Valve Stenosis
Matrix metalloproteinase-2 is associated with tenascin-C in calcific aortic stenosis.
Aortic Valve Stenosis
MMP-2/TIMP-2/TIMP-4 versus MMP-9/TIMP-3 in transition from compensatory hypertrophy and angiogenesis to decompensatory heart failure.
Appendicitis
A local imbalance between MMP and TIMP may have an implication on the severity and course of appendicitis.
Arrhythmias, Cardiac
Suppression of ?1-Adrenoceptor Autoantibodies is Involved in the Antiarrhythmic Effects of Omega-3 Fatty Acids in Male and Female Hypertensive Rats.
Arteriosclerosis
Binding of 92 kDa and 72 kDa progelatinases to insoluble elastin modulates their proteolytic activation.
Arteriosclerosis
MMP-2 expression is associated with rapidly proliferative arteriosclerosis in the flexor tenosynovium and pain severity in carpal tunnel syndrome.
Arteriovenous Fistula
Arterial enlargement in response to high flow requires early expression of matrix metalloproteinases to degrade extracellular matrix.
Arteriovenous Fistula
Expression of Hypoxia Inducible Factor-1alpha, Macrophage Migration Inhibition Factor, Matrix Metalloproteinase-2 and ?9, and Their Inhibitors in Hemodialysis Grafts and Arteriovenous Fistulas.
Arteriovenous Fistula
Increased expression of HIF-1alpha, VEGF-A and its receptors, MMP-2, TIMP-1, and ADAMTS-1 at the venous stenosis of arteriovenous fistula in a mouse model with renal insufficiency.
Arteriovenous Fistula
Serum metalloproteinases MMP-2, MMP-9, and metalloproteinase tissue inhibitors in patients are associated with arteriovenous fistula maturation.
Arteriovenous Fistula
The rat femoral arteriovenous fistula model: increased expression of matrix metalloproteinase-2 and -9 at the venous stenosis.
Arteriovenous Malformations
Elevated Expression of Matrix Metalloproteinase-9 not Matrix Metalloproteinase-2 Contributes to Progression of Extracranial Arteriovenous Malformation.
Arteriovenous Malformations
Expression of osteopontin, matrix metalloproteinase-2 and -9 proteins in vascular instability in brain arteriovenous malformation.
Arteriovenous Malformations
Imbalance of matrix metalloproteinase-9 and matrix metalloproteinase tissue inhibitor-1 may contribute to hemorrhage in cerebellar arteriovenous malformations.
Arteritis
Elevated levels of 92-kd type IV collagenase (matrix metalloproteinase 9) in giant cell arteritis.
Arteritis
Metalloproteinase-2 and -9 in giant cell arteritis: involvement in vascular remodeling.
Arthralgia
Sulfated glucosamine inhibits MMP-2 and MMP-9 expressions in human fibrosarcoma cells.
Arthritis
A comprehensive review on controls in molecular imaging: lessons from MMP-2 imaging.
Arthritis
A correlation between knee cartilage degradation observed by arthroscopy and synovial proteinases activities.
Arthritis
A novel matrix metalloproteinase 2 (MMP2) terminal hemopexin domain mutation in a family with multicentric osteolysis with nodulosis and arthritis with cardiac defects.
Arthritis
Active synovial matrix metalloproteinase-2 is associated with radiographic erosions in patients with early synovitis.
Arthritis
Arthritis induced immunologically with cationic amidated bovine serum albumin in the guinea pig. A morphological and biochemical study on the destruction of articular cartilage.
Arthritis
Assessment of the clinical significance of gelatinase activity in patients with juvenile idiopathic arthritis using quantitative protein substrate zymography.
Arthritis
Cathepsin B and cystatin C play an inflammatory role in gouty arthritis of the knee.
Arthritis
Changes in MMP-2 and -9 activity and MMP-8 reactivity after amphotericin B induced synovitis and treatment with bufexamac.
Arthritis
Clinical Radiological and Molecular Profile of a Patient Affected With Multicentric Osteolysis Nodulosis and Arthropathy.
Arthritis
Clinical significance of gelatinases in septic arthritis of native and replaced knees.
Arthritis
Clitoria ternatea flower petals: Effect on TNFR1 neutralization via downregulation of synovial matrix metalloproteases.
Arthritis
Collagen type III content of the long head of the biceps tendon as an indicator of glenohumeral arthritis.
Arthritis
Dual neutralization of TNFR-2 and MMP-2 regulates the severity of S. aureus induced septic arthritis correlating alteration in the level of interferon gamma and interleukin-10 in terms of TNFR2 blocking.
Arthritis
Effects of high molecular weight hyaluronic acid on induced arthritis of the temporomandibular joint in rats.
Arthritis
Expression levels and association of gelatinases MMP-2 and MMP-9 and collagenases MMP-1 and MMP-13 with VEGF in synovial fluid of patients with arthritis.
Arthritis
Expression levels of matrix metalloproteinase (MMP)-9 and its specific inhibitor TIMP-1, in septic and aseptic arthritis of the knee.
Arthritis
Generation of glycosylated remnant epitopes from human collagen type II by gelatinase B.
Arthritis
Infliximab therapy does not modify MMP-2 and MMP-9 serum concentrations in chronic arthritis.
Arthritis
Isolation and characterization of human monoclonal antibodies specific to MMP-1A, MMP-2 and MMP-3.
Arthritis
Levels of Selected Matrix Metalloproteinases, Their Inhibitors in Saliva, and Oral Status in Juvenile Idiopathic Arthritis Patients vs. Healthy Controls.
Arthritis
Liposomes encapsulated dimethyl curcumin regulates dipeptidyl peptidase I activity, gelatinase release and cell cycle of spleen lymphocytes in-vivo to attenuate collagen induced arthritis in rats.
Arthritis
Macrophage migration inhibitory factor: a mediator of matrix metalloproteinase-2 production in rheumatoid arthritis.
Arthritis
Matrix metalloproteinase-2 contributes to joint destruction in group B streptococcus-induced arthritis.
Arthritis
Modulation of Systemic Metabolism by MMP-2: From MMP-2 Deficiency in Mice to MMP-2 Deficiency in Patients.
Arthritis
Multicentric osteolysis with nodulosis and arthropathy (MONA) with cardiac malformation, mimicking polyarticular juvenile idiopathic arthritis: case report and literature review.
Arthritis
Mutation of the matrix metalloproteinase 2 gene (MMP2) causes a multicentric osteolysis and arthritis syndrome.
Arthritis
Neutralization of MMP-2 and TNFR1 Regulates the Severity of S. aureus-Induced Septic Arthritis by Differential Alteration of Local and Systemic Proinflammatory Cytokines in Mice.
Arthritis
Neutralization of MMP-2 protects Staphylococcus aureus infection induced septic arthritis in mice and regulates the levels of cytokines.
Arthritis
Neutrophil gelatinase levels in plasma and synovial fluid of patients with rheumatic diseases.
Arthritis
New collagenolytic enzymes/cascade identified at the pannus-hard tissue junction in rheumatoid arthritis: destruction from above.
Arthritis
Post-translational activation of Mmp2 correlates with patterns of active collagen degradation during the development of the zebrafish tail.
Arthritis
Robust Therapeutic Efficacy of Matrix Metalloproteinase-2-Cleavable Fas-1-RGD Peptide Complex in Chronic Inflammatory Arthritis.
Arthritis
Spectrum of common and uncommon causes of knee joint hyaline cartilage degeneration and their key imaging features.
Arthritis
Sulfated glucosamine inhibits MMP-2 and MMP-9 expressions in human fibrosarcoma cells.
Arthritis
The role of matrix metalloproteinase-2 and matrix metalloproteinase-9 in antibody-induced arthritis.
Arthritis
The significance of altered gelatinase expression in the synovium of patient with arthritic effusions.
Arthritis
Transcriptional activation by p53 of the human type IV collagenase (gelatinase A or matrix metalloproteinase 2) promoter.
Arthritis
Zymographic analysis of latent and activated forms of matrix metalloproteinase-2 and -9 in synovial fluid: correlation to polymorphonuclear leukocyte infiltration and in response to infection.
Arthritis, Experimental
Effect of a derivatized tetrapeptide from lactoferrin on nitric oxide mediated matrix metalloproteinase-2 production by synovial fibroblasts in collagen-induced arthritis in rats.
Arthritis, Experimental
Penta-acetyl Geniposide Suppresses Migration, Invasion, and Inflammation of TNF-?-Stimulated Rheumatoid Arthritis Fibroblast-Like Synoviocytes Involving Wnt/?-Catenin Signaling Pathway.
Arthritis, Gouty
Clinical Correlation with the PA/Plasmin System in Septic Arthritis of the Knee.
Arthritis, Gouty
Urokinase-type plasminogen activator, receptor, and inhibitor correlating with gelatinase-B (MMP-9) contribute to inflammation in gouty arthritis of the knee.
Arthritis, Infectious
Clinical Correlation with the PA/Plasmin System in Septic Arthritis of the Knee.
Arthritis, Infectious
Determination of MMP-2 and -9 activities in synovial fluid of horses with osteoarthritic and arthritic joint diseases using gelatin zymography and immunocapture activity assays.
Arthritis, Infectious
Dual neutralization of TNFR-2 and MMP-2 regulates the severity of S. aureus induced septic arthritis correlating alteration in the level of interferon gamma and interleukin-10 in terms of TNFR2 blocking.
Arthritis, Infectious
Matrix metalloproteinase-2 contributes to joint destruction in group B streptococcus-induced arthritis.
Arthritis, Infectious
Neutralization of MMP-2 and TNFR1 Regulates the Severity of S. aureus-Induced Septic Arthritis by Differential Alteration of Local and Systemic Proinflammatory Cytokines in Mice.
Arthritis, Infectious
Neutralization of MMP-2 protects Staphylococcus aureus infection induced septic arthritis in mice and regulates the levels of cytokines.
Arthritis, Infectious
Prepatellar bursitis due to Brucella abortus: case report and analysis of the local immune response.
Arthritis, Infectious
Relative expression of matrix metalloproteinase-2 and -9 in synovial fluid from healthy calves and calves with experimentally induced septic arthritis.
Arthritis, Juvenile
Assessment of the clinical significance of gelatinase activity in patients with juvenile idiopathic arthritis using quantitative protein substrate zymography.
Arthritis, Juvenile
Clinical Radiological and Molecular Profile of a Patient Affected With Multicentric Osteolysis Nodulosis and Arthropathy.
Arthritis, Juvenile
Levels of Selected Matrix Metalloproteinases, Their Inhibitors in Saliva, and Oral Status in Juvenile Idiopathic Arthritis Patients vs. Healthy Controls.
Arthritis, Juvenile
Multicentric osteolysis with nodulosis and arthropathy (MONA) with cardiac malformation, mimicking polyarticular juvenile idiopathic arthritis: case report and literature review.
Arthritis, Psoriatic
Gelatinase expression and activity in the synovium and skin of patients with erosive psoriatic arthritis.
Arthritis, Psoriatic
MMP-2, MMP-9, TIMP-1 and TIMP-2 levels in patients with rheumatoid arthritis and psoriatic arthritis.
Arthritis, Psoriatic
Possible molecular mechanisms to account for the involvement of tryptase in the pathogenesis of psoriasis.
Arthritis, Rheumatoid
A trypsin sensitive stromelysin isolated from rheumatoid synovial fluid is an activator for matrix metalloproteinases.
Arthritis, Rheumatoid
Activation of progelatinase B in synovial fluids of patients with rheumatoid arthritis, with reference to stromelysin-1 and tissue inhibitor of matrix metalloproteinase-1.
Arthritis, Rheumatoid
Association Study of Matrix Metalloproteinases Gene Polymorphisms with Susceptibility to Rheumatoid Arthritis: A Meta-Analysis.
Arthritis, Rheumatoid
Autoactivation profiles of calcium-dependent matrix metalloproteinase-2 and -9 in inflammatory synovial fluid: effect of pyrophosphate and bisphosphonates.
Arthritis, Rheumatoid
Characterisation of the cell type-specificity of collagenase 3 mRNA expression in comparison with membrane type 1 matrix metalloproteinase and gelatinase A in the synovial membrane in rheumatoid arthritis.
Arthritis, Rheumatoid
Clinical Correlation with the PA/Plasmin System in Septic Arthritis of the Knee.
Arthritis, Rheumatoid
Delphinidin suppresses PMA-induced MMP-9 expression by blocking the NF-?B activation through MAPK signaling pathways in MCF-7 human breast carcinoma cells.
Arthritis, Rheumatoid
Differential regulation of matrix metalloproteinase 2 and matrix metalloproteinase 9 by activated protein C: relevance to inflammation in rheumatoid arthritis.
Arthritis, Rheumatoid
Elevated circulatory MMP-2 and MMP-9 levels and activities in patients with rheumatoid arthritis and systemic lupus erythematosus.
Arthritis, Rheumatoid
Elevation of activated protein C in synovial joints in rheumatoid arthritis and its correlation with matrix metalloproteinase 2.
Arthritis, Rheumatoid
Expression and tissue localization of membrane-types 1, 2, and 3 matrix metalloproteinases in rheumatoid synovium.
Arthritis, Rheumatoid
Expression of matrix metalloproteinase 9 (96-kd gelatinase B) in human rheumatoid arthritis.
Arthritis, Rheumatoid
Generation of glycosylated remnant epitopes from human collagen type II by gelatinase B.
Arthritis, Rheumatoid
Immunolocalisation studies on six matrix metalloproteinases and their inhibitors, TIMP-1 and TIMP-2, in synovia from patients with osteo- and rheumatoid arthritis.
Arthritis, Rheumatoid
In vivo activation of gelatinase B/MMP-9 by trypsin in acute pancreatitis is a permissive factor in streptozotocin-induced diabetes.
Arthritis, Rheumatoid
Liver X Receptor (LXR) regulates rheumatoid arthritis fibroblast-like synoviocytes invasiveness, MMP-2 activation, IL-6 and CXCL10.
Arthritis, Rheumatoid
Localization of matrix metalloproteinase 9 (92-kilodalton gelatinase/type IV collagenase = gelatinase B) in osteoclasts: implications for bone resorption.
Arthritis, Rheumatoid
Macrophage migration inhibitory factor: a mediator of matrix metalloproteinase-2 production in rheumatoid arthritis.
Arthritis, Rheumatoid
MMP-2, MMP-9, TIMP-1 and TIMP-2 levels in patients with rheumatoid arthritis and psoriatic arthritis.
Arthritis, Rheumatoid
MMP-2, TNF-? and NLRP1 polymorphisms in Chinese patients with ankylosing spondylitis and rheumatoid arthritis.
Arthritis, Rheumatoid
Neutrophil gelatinase levels in plasma and synovial fluid of patients with rheumatic diseases.
Arthritis, Rheumatoid
New collagenolytic enzymes/cascade identified at the pannus-hard tissue junction in rheumatoid arthritis: destruction from above.
Arthritis, Rheumatoid
Prepatellar bursitis due to Brucella abortus: case report and analysis of the local immune response.
Arthritis, Rheumatoid
Regulation of interleukin-1beta-induced chemokine production and matrix metalloproteinase 2 activation by epigallocatechin-3-gallate in rheumatoid arthritis synovial fibroblasts.
Arthritis, Rheumatoid
Stimulation of 92-kd gelatinase (matrix metalloproteinase 9) production by interleukin-17 in human monocyte/macrophages: a possible role in rheumatoid arthritis.
Arthritis, Rheumatoid
Suppression of adjuvant arthritis of rats by a novel matrix metalloproteinase-inhibitor.
Arthritis, Rheumatoid
Suppressive effect of secretory phospholipase A2 inhibitory peptide on interleukin-1beta-induced matrix metalloproteinase production in rheumatoid synovial fibroblasts, and its antiarthritic activity in hTNFtg mice.
Arthritis, Rheumatoid
Taurine chloramine differentially inhibits matrix metalloproteinase 1 and 13 synthesis in interleukin-1beta stimulated fibroblast-like synoviocytes.
Arthritis, Rheumatoid
The gelatinase inhibitory activity of tetracyclines and chemically modified tetracycline analogues as measured by a novel microtiter assay for inhibitors.
Arthritis, Rheumatoid
The role of matrix metalloproteinase-2 and matrix metalloproteinase-9 in antibody-induced arthritis.
Arthritis, Rheumatoid
TNF-alpha-mediated expression of membrane-type matrix metalloproteinase in rheumatoid synovial fibroblasts.
Arthritis, Rheumatoid
[Polymorphism of gene promotor region for MMP-2 in rheumatoid arthritis]
Asbestosis
Serum concentrations of Krebs von den Lungen-6, surfactant protein D, and matrix metalloproteinase-2 as diagnostic biomarkers in patients with asbestosis and silicosis: a case-control study.
Asthma
Collagen I and thrombin activate MMP-2 by MMP-14-dependent and -independent pathways: implications for airway smooth muscle migration.
Asthma
Elevated gelatinase activity in pulmonary alveolar proteinosis: role of macrophage-colony stimulating factor.
Asthma
Elevated serum matrix metalloprotease (MMP-2) as a candidate biomarker for stable COPD.
Asthma
Enhancement of gelatinase activity during development of subepithelial fibrosis in a murine model of asthma.
Asthma
Expression of Matrix Metalloproteinases and Their Tissue Inhibitors in Chronic Rhinosinusitis With Nasal Polyps: Etiopathogenesis and Recurrence.
Asthma
Highly Protective Association of MMP-2-1306C/T Promoter Polymorphism With Asthma in a North Indian Population: A Pilot Study.
Asthma
Increased circulating 92 kDa matrix metalloproteinase (MMP-9) activity in exacerbations of asthma.
Asthma
Increased release of matrix metalloproteinase-9 in the plasma of acute severe asthmatic patients.
Asthma
Inhibition of matrix metalloproteinases prevents allergen-induced airway inflammation in a murine model of asthma.
Asthma
Interleukin-13 induces collagen type-1 expression through matrix metalloproteinase-2 and transforming growth factor-?1 in airway fibroblasts in asthma.
Asthma
Matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases in sputum from patients with bronchial asthma.
Asthma
Matrix metalloproteinases in the pathogenesis of asthma and COPD: implications for therapy.
Asthma
MiRNA-192-5p attenuates airway remodeling and autophagy in asthma by targeting MMP-16 and ATG7.
Asthma
Relationship between matrix production by bronchial fibroblasts and lung function and AHR in asthma.
Asthma
Role of Matrix Metalloproteinases-1 and -2 in Interleukin-13-Suppressed Elastin in Airway Fibroblasts in Asthma.
Asthma
Significant Association of MMP2 Promoter Genotypes to Asthma Susceptibility in Taiwan.
Asthma
Soluble membrane-type 1 matrix metalloproteinase (MT1-MMP) and gelatinase A (MMP-2) in induced sputum and bronchoalveolar lavage fluid of human bronchial asthma and bronchiectasis.
Asthma
Tachykinins induce gelatinase production by guinea pig alveolar macrophages: involvement of NK2 receptors.
Asthma
[Effect of triggering receptor expressed on myeloid cells 2 overexpression on airway inflammation and remodeling in mice with allergic asthma].
Asthma
[Effects of Fritillariae Cirrhosae Bulbus on MMP-2,MMP-9 and TIMP-1 in murine asthma model].
Asthma
[Regulatory effects of inhaled steroids on expression of matrix metalloproteinase-9 and its inhibitor in asthmatic rats]
Astrocytoma
An extracellular proteasome-like structure from C6 astrocytoma cells with serine collagenase IV activity and metallo-dependent activity on alpha-casein and beta-insulin.
Astrocytoma
Differential expression of membrane-type matrix metalloproteinase and its correlation with gelatinase A activation in human malignant brain tumors in vivo and in vitro.
Astrocytoma
Divergent effects of oncostatin M on astroglioma cells: influence on cell proliferation, invasion, and expression of matrix metalloproteinases.
Astrocytoma
Evaluation of invasiveness of astrocytoma using (1)H-magnetic resonance spectroscopy: correlation with expression of matrix metalloproteinase-2.
Astrocytoma
Evaluation of the effects of swainsonine, captopril, tangeretin and nobiletin on the biological behaviour of brain tumour cells in vitro.
Astrocytoma
Expression and localization of 72 kDa type IV collagenase (MMP-2) in human malignant gliomas in vivo.
Astrocytoma
Expression and prognostic impact of matrix metalloproteinase-2 (MMP-2) in astrocytomas.
Astrocytoma
Expression of hepatocyte growth factor and matrix metalloproteinase-2 in human glioma.
Astrocytoma
Expression of matrix metalloproteinases and their tissue inhibitors in human brain tumors.
Astrocytoma
Expression of MMP-2, MMP-7, MMP-9, MMP-10 and MMP-11 in human astrocytic and oligodendroglial gliomas.
Astrocytoma
Expression of timp-1, timp-2, 72-kda and 92-kda type-iv collagenase transcripts in human astrocytoma cell-lines - correlation with astrocytoma cell invasiveness.
Astrocytoma
Expression, association with clinicopathological features and prognostic potential of CEP55, p-Akt, FoxM1 and MMP-2 in astrocytoma.
Astrocytoma
Ghrelin and the growth hormone secretagogue receptor constitute a novel autocrine pathway in astrocytoma motility.
Astrocytoma
l-Glutamate in Middlebrook 7H9 culture medium upregulates matrix metalloproteinase-2 secretion from human astrocytoma cells.
Astrocytoma
Localization of gelatinase activities in glioma tissues by film in situ zymography.
Astrocytoma
Loss of Inhibitor of Growth (ING-4) Is Implicated in the Pathogenesis and Progression of Human Astrocytomas.
Astrocytoma
Matrix metalloproteinase 2 (MMP-2) immunoreactive protein is associated with poor grade and survival in brain neoplasms.
Astrocytoma
Matrix metalloproteinase-9 interplays with the IGFBP2-IGFII complex to promote cell growth and motility in astrocytomas.
Astrocytoma
Matrix metalloproteinases in human gliomas: activation of matrix metalloproteinase-2 (MMP-2) may be correlated with membrane-type-1 matrix metalloproteinase (MT1-MMP) expression.
Astrocytoma
Promotion of astrocytoma cell invasion by micro RNA-22 targeting of tissue inhibitor of matrix metalloproteinase-2.
Astrocytoma
Specific matrix metalloproteinase profiles in the cerebrospinal fluid correlated with the presence of malignant astrocytomas, brain metastases, and carcinomatous meningitis.
Astrocytoma
The effects of exogenous growth factors on matrix metalloproteinase secretion by human brain tumour cells.
Astrocytoma
The Evaluation of AREG, MMP-2, CHI3L1, GFAP, and OPN Serum Combined Value in Astrocytic Glioma Patients' Diagnosis and Prognosis.
Astrocytoma
The importance of cell density in the interpretation of growth factor effects on collagenase IV activity release and extracellular matrix production from C6 astrocytoma cells.
Astrocytoma
The transcription factors Sp1, Sp3, and AP-2 are required for constitutive matrix metalloproteinase-2 gene expression in astroglioma cells.
Astrocytoma
Transcriptional suppression of matrix metalloproteinase-2 gene expression in human astroglioma cells by TNF-alpha and IFN-gamma.
Astrocytoma
[Increased expression of gelatinases A and B, matrilysin and TIMP-1 genes in human malignant gliomas ]
Ataxia
Ataxia telangiectasia-mutated gene is a possible biomarker for discrimination of infiltrative deep penetrating nevi and metastatic vertical growth phase melanoma.
Atherosclerosis
(-)-Epicatechin gallate blocks the development of atherosclerosis by regulating oxidative stress in vivo and in vitro.
Atherosclerosis
A comprehensive review on controls in molecular imaging: lessons from MMP-2 imaging.
Atherosclerosis
Aging increases aortic MMP-2 activity and angiotensin II in nonhuman primates.
Atherosclerosis
Anti-inflammatory effects of atorvastatin: modulation by the T-786C polymorphism in the endothelial nitric oxide synthase gene.
Atherosclerosis
Atherosclerosis and the protective role played by different proteins in apolipoprotein E-deficient mice.
Atherosclerosis
Biomarkers and location of atherosclerosis: Matrix metalloproteinase-2 may be related to intracranial atherosclerosis.
Atherosclerosis
Carvedilol, a pharmacological antioxidant, inhibits neointimal matrix metalloproteinase-2 and -9 in experimental atherosclerosis.
Atherosclerosis
Chinese Yellow Wine and Red Wine Inhibit Matrix Metalloproteinase-2 and Improve Atherosclerotic Plaque in LDL Receptor Knockout Mice.
Atherosclerosis
Circulating Matrix Metalloproteinase-2 Is an Independent Correlate of Proteinuria in Patients with Chronic Kidney Disease.
Atherosclerosis
Coexpression of cyclooxygenase-2 and matrix metalloproteinases in human aortic atherosclerotic lesions.
Atherosclerosis
Correlation between plasma angiopoietin-1, angiopoietin-2 and matrix metalloproteinase-2 in coronary heart disease.
Atherosclerosis
Crosstalk Between Enzyme Matrix Metalloproteinases 2 and 9 and Regulatory T Cell Immunity in the Global Burden of Atherosclerosis.
Atherosclerosis
Delphinidin suppresses PMA-induced MMP-9 expression by blocking the NF-?B activation through MAPK signaling pathways in MCF-7 human breast carcinoma cells.
Atherosclerosis
Distribution profiles of membrane Type-1 matrix metalloproteinase (MT1-MMP), matrix metalloproteinase-2 (MMP-2) and cyclooxygenase-2 (COX-2) in rabbit atherosclerosis: comparison with plaque instability analysis.
Atherosclerosis
Effect of MMP-2 deficiency on atherosclerotic lesion formation in apoE-deficient mice.
Atherosclerosis
Emodin inhibits tumor necrosis factor-?-induced migration and inflammatory responses in rat aortic smooth muscle cells.
Atherosclerosis
Facial amphipathic deoxycholic acid-modified polyethyleneimine for efficient MMP-2 siRNA delivery in vascular smooth muscle cells.
Atherosclerosis
Furin-like proprotein convertases are central regulators of the membrane type matrix metalloproteinase-pro-matrix metalloproteinase-2 proteolytic cascade in atherosclerosis.
Atherosclerosis
Heparin inhibits the production of matrix metalloproteinase-2 and improves atherosclerosis in LDL receptor-deficient mice.
Atherosclerosis
High glucose alters matrix metalloproteinase expression in two key vascular cells: potential impact on atherosclerosis in diabetes.
Atherosclerosis
High glucose enhance expression of matrix metalloproteinase-2 in smooth muscle cells.
Atherosclerosis
Identification of 92-kD gelatinase in human coronary atherosclerotic lesions. Association of active enzyme synthesis with unstable angina.
Atherosclerosis
Identification of novel, functional genetic variants in the human matrix metalloproteinase-2 gene: role of Sp1 in allele-specific transcriptional regulation.
Atherosclerosis
Immortalization of human aortic smooth muscle cells with origin-minus simian virus 40 DNA.
Atherosclerosis
Increased expression of 72-kd type IV collagenase (MMP-2) in human aortic atherosclerotic lesions.
Atherosclerosis
Influence of elastin-derived peptides on metalloprotease production in endothelial cells.
Atherosclerosis
Inhibitory effect of recombinant human CXCL8(3-72)K11R/G31P on atherosclerotic plaques in a mouse model of atherosclerosis.
Atherosclerosis
Laminar high shear stress up-regulates type IV collagen synthesis and down-regulates MMP-2 secretion in endothelium. A quantitative analysis.
Atherosclerosis
Markers of increased atherosclerotic risk in patients with chronic kidney disease: a preliminary study.
Atherosclerosis
Matrix Metalloproteinase 2 and Osteoprotegrin as New Markers of Increased Atherosclerotic Risk in Egyptian Patients with Chronic Kidney Disease.
Atherosclerosis
Matrix metalloproteinase-2 on activated platelets triggers endothelial PAR-1 initiating atherosclerosis.
Atherosclerosis
Matrix metalloproteinases 2 and 9 in human atherosclerotic and non-atherosclerotic cerebral aneurysms.
Atherosclerosis
Matrix Metalloproteinases and Subclinical Atherosclerosis in Chronic Kidney Disease: A Systematic Review.
Atherosclerosis
Matrix Metalloproteinases in Vascular Disease - A Potential Therapeutic Target?
Atherosclerosis
Methylation in the matrix metalloproteinase-2 gene is associated with cerebral ischemic stroke.
Atherosclerosis
MMP-2 and MMP-9 are prominent matrix metalloproteinases during atherosclerosis development in the Ldlr(-/-)Apob(100/100) mouse.
Atherosclerosis
Pentosan polysulfate inhibits atherosclerosis in Watanabe heritable hyperlipidemic rabbits: differential modulation of metalloproteinase-2 and -9.
Atherosclerosis
Platelet-derived growth factor-BB induces matrix metalloproteinase-2 expression and rat vascular smooth muscle cell migration via ROCK and ERK/p38 MAPK pathways.
Atherosclerosis
Possible Mechanisms of Di(2-ethylhexyl) Phthalate-Induced MMP-2 and MMP-9 Expression in A7r5 Rat Vascular Smooth Muscle Cells.
Atherosclerosis
Pterostilbene Inhibits Vascular Smooth Muscle Cells Migration and Matrix Metalloproteinase-2 through Modulation of MAPK Pathway.
Atherosclerosis
Rapid release of matrix metalloproteinase (MMP)-2 by thrombin in the rat aorta: modulation by protein tyrosine kinase/phosphatase.
Atherosclerosis
Renal Denervation Promotes Atherosclerosis in Hypertensive Apolipoprotein E-Deficient Mice Infused with Angiotensin II.
Atherosclerosis
Role of oncogene 24p3 neutrophil gelatinase-associated lipocalin (NGAL) in digestive system cancers.
Atherosclerosis
Rosuvastatin inhibits MMP-2 expression and limits the progression of atherosclerosis in LDLR-deficient mice.
Atherosclerosis
Silencing of long non-coding RNA H19 downregulates CTCF to protect against atherosclerosis by upregulating PKD1 expression in ApoE knockout mice.
Atherosclerosis
Smooth muscle NADPH oxidase 4 promotes angiotensin II-induced aortic aneurysm and atherosclerosis by regulating osteopontin.
Atherosclerosis
Synthesis of a beta-tetrapeptide analog as a mother compound for the development of matrix metalloproteinase-2-imaging agents.
Atherosclerosis
Tanshinone IIA downregulates the CD40 expression and decreases MMP-2 activity on atherosclerosis induced by high fatty diet in rabbit.
Atherosclerosis
The expression of CD40-CD40L and activities of matrix metalloproteinases in atherosclerotic rats.
Atherosclerosis
The role of matrix metalloproteinases 2 in atherosclerosis of patients with chronic kidney disease in type 2 diabetes.
Atherosclerosis
Thrombin-thrombomodulin activation of protein C facilitates the activation of progelatinase A.
Atherosclerosis
Treatment of ?-thujaplicin counteracts di(2-ethylhexyl)phthalate (DEHP)-exposed vascular smooth muscle activation, inflammation and atherosclerosis progression.
Atherosclerosis
Urokinase-type plasminogen activator and metalloproteinase-2 are independently related to the carotid atherosclerosis in haemodialysis patients.
Atherosclerosis
[Effects of PPAR-gamma agonist and MMP-2 on formation of atherosclerosis plaque in rabbits]
Atherosclerosis
[Impacts of atovastatin and tinidazole on cardiac muscle inflammation factors of tumor necrosis factor-?, interleukin-1 and metalloproteinase-2 of experimental rabbits with atherosclerosis and periodontitis].
Atherosclerosis
[The expression of matrix metalloproteinase-2,9 on atherosclerosis in experimental rats by treatment of 2,3,4',5-tetrahydroxystilbene -2-0-beta-D glucoside].
Atrial Fibrillation
Ageing related down-regulation of myocardial connexin-43 and up-regulation of MMP-2 may predict propensity to atrial fibrillation in experimental animals.
Atrial Fibrillation
Associations Between Neutrophil Gelatinase Associated Lipocalin, Neutrophil-to-Lymphocyte Ratio, Atrial Fibrillation and Renal Dysfunction in Chronic Heart Failure.
Atrial Fibrillation
Associations of MMP-2, BAX, and Bcl-2 mRNA and Protein Expressions with Development of Atrial Fibrillation.
Atrial Fibrillation
Atrial extracellular matrix remodeling and the maintenance of atrial fibrillation.
Atrial Fibrillation
Effects of amiodarone on electrical and structural remodeling induced in a canine rapid pacing-induced persistent atrial fibrillation model.
Atrial Fibrillation
Impact of Biomarkers of Inflammation and Extracellular Matrix Turnover on the Outcome of Atrial Fibrillation Ablation: Importance of Matrix Matalloproteinase-2 as a Predictor of Atrial Fibrillation Recurrence.
Atrial Fibrillation
Impact of matrix metalloproteinase-2 levels on long-term outcome following pharmacological or electrical cardioversion in patients with atrial fibrillation.
Atrial Fibrillation
MMP-2 and TIMP-2 gene polymorphisms and susceptibility to atrial fibrillation in Chinese Han patients with hypertensive heart disease.
Atrial Fibrillation
Oral direct renin inhibitor aliskiren reduces in vivo oxidative stress and serum matrix metalloproteinase-2 levels in patients with permanent atrial fibrillation.
Atrial Fibrillation
The role of matrix metalloproteinase-2 in the treatment of atrial fibrillation recurrence after a radiofrequency modified maze procedure.
Atrial Fibrillation
[Clinical on molecular basis of atrial fibrosis in patients with atrial fibrillation investigation]
Autoimmune Diseases
Changes of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) in the serum of patients with autoimmune diseases: association with age and disease activity.
Autoimmune Diseases
Deficiency of gelatinase B/MMP-9 aggravates lpr-induced lymphoproliferation and lupus-like systemic autoimmune disease.
Autoimmune Diseases
In vivo activation of gelatinase B/MMP-9 by trypsin in acute pancreatitis is a permissive factor in streptozotocin-induced diabetes.
Autoimmune Pancreatitis
Differential Diagnosis of Autoimmune Pancreatitis From Pancreatic Cancer by Analysis of Serum Gelatinase Levels.
Azoospermia
Quantitative differences in matrix metalloproteinase (MMP)-2, but not in MMP-9, tissue inhibitor of metalloproteinase (TIMP)-1 or TIMP-2, in seminal plasma of normozoospermic and azoospermic patients.
Bacteremia
Association between the presence of enterococcal virulence factors gelatinase, hemolysin, and enterococcal surface protein and mortality among patients with bacteremia due to Enterococcus faecalis.
Bacteremia
Bacterial and host factors affecting Pseudomonas aeruginosa colonization versus bacteremia in granulocytopenic patients.
Bacteremia
[Virulence genes and bacteriocins in Enterococcus faecalis strains isolated from different clinical samples in Maule Region, Chile].
Bacterial Infections
Matrix metalloproteinase 2 of grass carp Ctenopharyngodon idella (CiMMP2) is involved in the immune response against bacterial infection.
Bacterial Infections
Regulation of MMPs and TIMPs by IL-1beta during corneal ulceration and infection.
Bicuspid Aortic Valve Disease
Differential expression of MMP-2, MMP-9 and TIMP proteins in thoracic aortic aneurysm - comparison with and without bicuspid aortic valve: a meta-analysis.
Bicuspid Aortic Valve Disease
Endothelial function and plasma matrix metalloproteinase-2 levels and their association with the size and elastic properties of the ascending aorta in first-degree relatives of bicuspid aortic valve patients.
Bicuspid Aortic Valve Disease
Endothelial function, carotid-femoral stiffness, and plasma matrix metalloproteinase-2 in men with bicuspid aortic valve and dilated aorta.
Bicuspid Aortic Valve Disease
Enlarged Size and Impaired Elastic Properties of the Ascending Aorta are Associated with Endothelial Dysfunction and Elevated Plasma Matrix Metalloproteinase-2 Level in Patients with Bicuspid Aortic Valve.
Bicuspid Aortic Valve Disease
Expression of matrix metalloproteinases and endogenous inhibitors within ascending aortic aneurysms of patients with bicuspid or tricuspid aortic valves.
Bicuspid Aortic Valve Disease
Matrix metalloproteinase activity in thoracic aortic aneurysms associated with bicuspid and tricuspid aortic valves.
Bicuspid Aortic Valve Disease
Matrix metalloproteinase-2 and -9 levels in patients with dilated ascending aorta and bicuspid aortic valve.
Bicuspid Aortic Valve Disease
Matrix Metalloproteinase-2 Isoforms Differ within the Aortic Wall of Ascending Aortic Aneurysms Associated with Bicuspid Aortic Valve.
Bicuspid Aortic Valve Disease
Nonstenotic bicuspid aortic valve is associated with elevated plasma asymmetric dimethylarginine.
Bicuspid Aortic Valve Disease
The Role Matrix Metalloproteinases in the Production of Aortic Aneurysm.
Bicuspid Aortic Valve Disease
Vascular matrix remodeling in patients with bicuspid aortic valve malformations: implications for aortic dilatation.
Biliary Atresia
Matrilysin (MMP-7) is a major matrix metalloproteinase upregulated in biliary atresia-associated liver fibrosis.
Blast Crisis
Matrix metalloproteinase production by bone marrow mononuclear cells from normal individuals and patients with acute and chronic myeloid leukemia or myelodysplastic syndromes.
Blister
92-kD gelatinase is produced by eosinophils at the site of blister formation in bullous pemphigoid and cleaves the extracellular domain of recombinant 180-kD bullous pemphigoid autoantigen.
Blister
A case of anaphylactoid purpura with multiple blister formation: possible pathophysiological role of gelatinase (MMP-9).
Blister
Altered expression of basement membrane proteins and their integrin receptors in lichen planus: possible pathogenetic role of gelatinases A and B.
Blister
Correlation between Tissue Characterization and Dynamic Expression of Matrix Metalloproteinase-2 and Its Tissue Inhibitor in Conjunctival Filtering Bleb of Rats.
Blister
Effect of Qingguangan on the expressions of MMP-2 and MMP-9 in filtering bleb after trabeculectomy in rabbits.
Blister
Exogenous Tissue Inhibitor of Metalloproteinase-2 Affects Matrix Metalloproteinase-2 Expression in Conjunctival Filtering Blebs and Bleb Scarring in Rats.
Blister
Increased expression of matrix metalloproteinase-2, matrix metalloproteinase-9 and matrix metalloproteinase-13 in lesional skin of bullous pemphigoid.
Blister
Influence of aging, localization, glucocorticoids and isotretinoin on matrix metalloproteases 2 (MMP-2) and 9 (MMP-9) in suction blister fluids.
Blister
Interleukin 1 alpha (IL-1 alpha) in human skin in vivo: lack of correlation to markers of collagen metabolism.
Blister
Matrix metalloproteinases (MMP-1, MMP-2, MMP-3 and MMP-9, and TIMP-1, TIMP-2 and TIMP-3) and markers for vascularization in functioning and non-functioning bleb capsules of glaucoma drainage implants.
Blister
Matrix- metalloproteinase -2, -8 and -9 in serum and skin blister fluid in patients with severe sepsis.
Blister
MMP expression in leaking filtering blebs and tears after glaucoma filtering surgery.
Blister
Nonlethal oxidant injury to human retinal pigment epithelium cells causes cell membrane blebbing but decreased MMP-2 activity.
Blister
Photosensitization of uroporphyrin augments the ultraviolet A-induced synthesis of matrix metalloproteinases in human dermal fibroblasts.
Blister
Possible involvement of gelatinase A (MMP2) and gelatinase B (MMP9) in toxic epidermal necrolysis or Stevens-Johnson syndrome.
Blister
Topical synthetic inhibitor of matrix metalloproteinases delays epidermal regeneration of human wounds.
Bone Diseases
MMP-2, MMP-9 and activin A blood levels in patients with breast cancer or prostate cancer metastatic to the bone.
Bone Diseases, Metabolic
[Relationships between circulating matrix metalloproteinase-1, -2 and metalloproteinase-1 levels and bone biochemical markers and bone mineral density in Chinese postmenopausal women]
Bone Resorption
1alpha,25-dihydroxyvitamin D3 regulates the expression of membrane-type matrix metalloproteinase-1 in normal human osteoblast-like cells.
Bone Resorption
Alendronate blocks TGF-beta1 stimulated collagen 1 degradation by human prostate PC-3 ML cells.
Bone Resorption
Basigin-2 upregulated by receptor activator of NF-?B ligand enhances lung cancer-induced osteolytic lesions.
Bone Resorption
Biphenyl sulfonylamino methyl bisphosphonic acids as inhibitors of matrix metalloproteinases and bone resorption.
Bone Resorption
Effects of 17beta-estradiol and progesterone on the expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in rat osteoblasts.
Bone Resorption
Effects of 17beta-estradiol on the expression of matrix metalloproteinase-1, -2 and tissue inhibitor of metalloproteinase-1 in human osteoblast-like cell cultures.
Bone Resorption
Effects of 17beta-estradiol on the expression of membrane type 1 matrix metalloproteinase (MT1-MMP) and MMP-2 in human osteoblastic MG-63 cell cultures.
Bone Resorption
Effects of bisphosphonate on the release of MMP-2 from cultured human osteoblasts.
Bone Resorption
EGF and IL-1 alpha modulate the release of collagenase, gelatinase and TIMP-1 as well as the release of calcium by rabbit calvarial bone explants.
Bone Resorption
Expression of metalloproteinases and tissue inhibitors of metalloproteinases in human osteoblast-like cells: differentiation is associated with repression of metalloproteinase biosynthesis.
Bone Resorption
Expression of MMP-2, 9 and 13 in newly formed bone after sinus augmentation using inorganic bovine bone in human.
Bone Resorption
Impaired bone resorption to prostaglandin E2 in prostaglandin E receptor EP4-knockout mice.
Bone Resorption
Inhibition of bone resorption in vitro by selective inhibitors of gelatinase and collagenase.
Bone Resorption
Inhibition of matrix metalloproteinase-mediated periodontal bone loss in rats: a comparison of 6 chemically modified tetracyclines.
Bone Resorption
Interleukin-1 and tumor necrosis factor-alpha induce collagenolysis and bone resorption by regulation of matrix metalloproteinase-2 in mouse calvarial bone cells.
Bone Resorption
Localization of matrix metalloproteinase 9 (92-kilodalton gelatinase/type IV collagenase = gelatinase B) in osteoclasts: implications for bone resorption.
Bone Resorption
Phase I and pharmacological study of the oral matrix metalloproteinase inhibitor, MMI270 (CGS27023A), in patients with advanced solid cancer.
Bone Resorption
Potential anti-arthritic and anti-inflammatory effects of TNF-? processing inhibitor-1 (TAPI-1): A new approach to the treatment of S. aureus arthritis.
Bone Resorption
Resveratrol Suppresses Matrix Metalloproteinase-2 Activation Induced by Lipopolysaccharide in Mouse Osteoblasts via Interactions with AMP-Activated Protein Kinase and Suppressor of Cytokine Signaling 1.
Bone Resorption
Role of Chemically Modified Tetracyclines in the Management of Periodontal Diseases: A Review.
Bone Resorption
Role of RANKL-induced osteoclast formation and MMP-dependent matrix degradation in bone destruction by breast cancer metastasis.
Bone Resorption
Soluble IL-6R alpha upregulated IL-6, MMP-1 and MMP-2 secretion in bone marrow stromal cells.
Bone Resorption
Strontium ranelate inhibits key factors affecting bone remodeling in human osteoarthritic subchondral bone osteoblasts.
Bone Resorption
The effect of phenytoin on collagenase and gelatinase activities in UMR 106-01 rat osteoblastic osteosarcoma cells.
Bone Resorption
The effects of selective inhibitors of matrix metalloproteinases (MMPs) on bone resorption and the identification of MMPs and TIMP-1 in isolated osteoclasts.
Bone Resorption
The virulence factor GroEL promotes gelatinase secretion from cells in the osteoblast lineage: Implication for direct crosstalk between bacteria and adult cells.
Bone Resorption
Timp-1, -2 and -3 show coexpression with gelatinases A and B during mouse tooth morphogenesis.
Bone Resorption
Wnt signaling pathway inhibitors as promising diagnostic serum markers of osteolytic bone metastasis.
Bone Resorption
Zoledronate is a potent inhibitor of myeloma cell growth and secretion of IL-6 and MMP-1 by the tumoral environment.
Bowen's Disease
Differential expression of matrix metalloproteinase (MMP)-2, MMP-9 and tissue inhibitor of metalloproteinase (TIMP)-1 and TIMP-2 in non-melanoma skin cancer: implications for tumour progression.
Bowen's Disease
Immunolocalizations of human gelatinase (type IV collagenase, MMP-9) and TIMP (tissue inhibitor of metalloproteinases) in normal epidermis and some epidermal tumors.
Brain Contusion
Brain contusions induce a strong local overexpression of MMP-9. Results of a pilot study.
Brain Diseases
HIV-1 gp120 upregulates matrix metalloproteinases and their inhibitors in a rat model of HIV encephalopathy.
Brain Edema
2-Chloroethanol Induced Upregulation of Matrix Metalloproteinase-2 in Primary Cultured Rat Astrocytes Via MAPK Signal Pathways.
Brain Edema
Chlorogenic acid ameliorates brain damage and edema by inhibiting matrix metalloproteinase-2 and 9 in a rat model of focal cerebral ischemia.
Brain Edema
Effect of Propofol Post-treatment on Blood-Brain Barrier Integrity and Cerebral Edema After Transient Cerebral Ischemia in Rats.
Brain Edema
Erythropoietin attenuates intracerebral hemorrhage by diminishing matrix metalloproteinases and maintaining blood-brain barrier integrity in mice.
Brain Edema
HMGB1 inhibitor glycyrrhizin attenuates intracerebral hemorrhage-induced injury in rats.
Brain Edema
Matrix metalloproteinase inhibition attenuates brain edema after surgical brain injury.
Brain Edema
MATRIX METALLOPROTEINASE INHIBITION ATTENUATES BRAIN EDEMA IN AN IN VIVO MODEL OF SURGICALLY-INDUCED BRAIN INJURY.
Brain Edema
Matrix metalloproteinase inhibition attenuates brain edema in an in vivo model of surgically-induced brain injury.
Brain Edema
MATRIX METALLOPROTEINASE INHIBITION ATTENUATES BRAIN EDEMA IN AN IN VIVO MODEL OF SURGICALLY-INDUCED BRAIN INJURY.
Brain Edema
Matrix metalloproteinase-2 deletions protect against hemorrhagic transformation after 1h of cerebral ischemia and 23h of reperfusion.
Brain Edema
Reduced brain edema and matrix metalloproteinase (MMP) expression by pre-reperfusion infusion into ischemic territory in rat.
Brain Edema
SIRT1 inhibition by sirtinol aggravates brain edema after experimental subarachnoid hemorrhage.
Brain Edema
[Study on expression of matrix metalloproteinase-2 and matrix metalloproteinase-9 in brain tissue adjacent to hemorrhage after brain hemorrhage in human]
Brain Infarction
Effects of tissue plasminogen activator on cerebral microvessels of rats during focal cerebral ischemia and reperfusion.
Brain Infarction
Matrix metalloproteinase-2 deletions protect against hemorrhagic transformation after 1h of cerebral ischemia and 23h of reperfusion.
Brain Injuries
Carnosine Attenuates Brain Oxidative Stress and Apoptosis After Intracerebral Hemorrhage in Rats.
Brain Injuries
Delayed administration of a matrix metalloproteinase inhibitor limits progressive brain injury after hypoxia-ischemia in the neonatal rat.
Brain Injuries
Examination of Gelatinase Isoforms in Rodent Models of Acute Neurodegenerative Diseases Using Two-Dimensional Zymography.
Brain Injuries
Heterogeneity of serum gelatinases MMP-2 and MMP-9 isoforms and charge variants.
Brain Injuries
Matrix metalloproteinase 2 gene knockout has no effect on acute brain injury after focal ischemia.
Brain Injuries
Matrix metalloproteinase inhibitor KB-R7785 attenuates brain damage resulting from permanent focal cerebral ischemia in mice.
Brain Injuries
Matrix metalloproteinase-2 deletions protect against hemorrhagic transformation after 1h of cerebral ischemia and 23h of reperfusion.
Brain Injuries
Matrix metalloproteinase-2 or -9 deletions protect against hemorrhagic transformation during early stage of cerebral ischemia and reperfusion.
Brain Injuries
Molecular pathology of pulmonary edema after injury in forensic autopsy cases.
Brain Injuries
Neuroprotection by inhibition of matrix metalloproteinases in a mouse model of intracerebral haemorrhage.
Brain Injuries
Proteolytic processed form of CXCL12 abolishes migration and induces apoptosis in neural stem cells in vitro.
Brain Injuries
Tumor necrosis factor-alpha-induced gelatinase B causes delayed opening of the blood-brain barrier: an expanded therapeutic window.
Brain Injuries
Two-dimensional zymography differentiates gelatinase isoforms in stimulated microglial cells and in brain tissues of acute brain injuries.
Brain Injuries, Traumatic
CXCL12/CXCR4 Axis Improves Migration of Neuroblasts Along Corpus Callosum by Stimulating MMP-2 Secretion After Traumatic Brain Injury in Rats.
Brain Injuries, Traumatic
Early Gelatinase Activity Is Not a Determinant of Long-Term Recovery after Traumatic Brain Injury in the Immature Mouse.
Brain Injuries, Traumatic
Synapse loss regulated by matrix metalloproteinases in traumatic brain injury is associated with hypoxia inducible factor-1alpha expression.
Brain Injuries, Traumatic
The role of matrix metalloproteinases in infant traumatic brain injury.
Brain Ischemia
?2-Adrenergic Receptor-Mediated HIF-1? Upregulation Mediates Blood Brain Barrier Damage in Acute Cerebral Ischemia.
Brain Ischemia
A non-steroidal anti-inflammatory agent provides significant protection during focal ischemic stroke with decreased expression of matrix metalloproteinases.
Brain Ischemia
Activation systems for latent matrix metalloproteinase-2 are upregulated immediately after focal cerebral ischemia.
Brain Ischemia
Angiotensin type 1 receptor blockage improves ischemic injury following transient focal cerebral ischemia.
Brain Ischemia
Chlorogenic acid ameliorates brain damage and edema by inhibiting matrix metalloproteinase-2 and 9 in a rat model of focal cerebral ischemia.
Brain Ischemia
Crocin protects against cerebral- ischemia-induced damage in aged rats through maintaining the integrity of blood-brain barrier.
Brain Ischemia
Early Abrogation of Gelatinase Activity Extends the Time Window for tPA Thrombolysis after Embolic Focal Cerebral Ischemia in Mice.
Brain Ischemia
Effect of neutrophil depletion on gelatinase expression, edema formation and hemorrhagic transformation after focal ischemic stroke.
Brain Ischemia
Expression and activation of matrix metalloproteinase-2 and -9 in rat brain after transient focal cerebral ischemia.
Brain Ischemia
Gelatinase activity imaged by activatable cell-penetrating peptides in cell-based and in vivo models of stroke.
Brain Ischemia
Green tea polyphenol (-)-epigallocatechin gallate reduces matrix metalloproteinase-9 activity following transient focal cerebral ischemia.
Brain Ischemia
Green tea polyphenol (-)-epigallocatechin gallate reduces neuronal cell damage and up-regulation of MMP-9 activity in hippocampal CA1 and CA2 areas following transient global cerebral ischemia.
Brain Ischemia
Inhibition of HIF-1? Reduced Blood Brain Barrier Damage by Regulating MMP-2 and VEGF During Acute Cerebral Ischemia.
Brain Ischemia
Inhibition of matrix metalloproteinase-2 and 9 by Piroxicam confer neuroprotection in cerebral ischemia: an in silico evaluation of the hypothesis.
Brain Ischemia
Inhibition of MMP-9 by a selective gelatinase inhibitor protects neurovasculature from embolic focal cerebral ischemia.
Brain Ischemia
Matrix metalloproteinase expression after human cardioembolic stroke: temporal profile and relation to neurological impairment.
Brain Ischemia
Matrix metalloproteinase-2 deletions protect against hemorrhagic transformation after 1h of cerebral ischemia and 23h of reperfusion.
Brain Ischemia
Matrix metalloproteinase-2 or -9 deletions protect against hemorrhagic transformation during early stage of cerebral ischemia and reperfusion.
Brain Ischemia
Matrix metalloproteinases increase very early during experimental focal cerebral ischemia.
Brain Ischemia
Melatonin decreases matrix metalloproteinase-9 activation and expression and attenuates reperfusion-induced hemorrhage following transient focal cerebral ischemia in rats.
Brain Ischemia
Protective effect of quercetin, a natural flavonoid against neuronal damage after transient global cerebral ischemia.
Brain Ischemia
Reduction of hemorrhagic transformation by PJ34, a poly(ADP-ribose)polymerase inhibitor, after permanent focal cerebral ischemia in mice.
Brain Ischemia
Resveratrol inhibits matrix metalloproteinases to attenuate neuronal damage in cerebral ischemia: a molecular docking study exploring possible neuroprotection.
Brain Ischemia
Role of matrix metalloproteinases in delayed neuronal damage after transient global cerebral ischemia.
Brain Ischemia
Stromelysin-1 and gelatinase A are upregulated before TNF-alpha in LPS-stimulated neuroinflammation.
Brain Ischemia
The significance of matrix metalloproteinase (MMP)-2 and MMP-9 in the ischemic stroke.
Brain Ischemia
Up-regulation of brain cytokines and metalloproteinases 1 and 2 contributes to neurological deficit and brain damage in transient ischemic stroke.
Brain Neoplasms
A nutrient mixture inhibits glioblastoma xenograft U-87 MG growth in male nude mice.
Brain Neoplasms
Adenovirus-mediated transfer of siRNA against MMP-2 mRNA results in impaired invasion and tumor-induced angiogenesis, induces apoptosis in vitro and inhibits tumor growth in vivo in glioblastoma.
Brain Neoplasms
Chapter 4 - Applications of nanotechnology in molecular imaging of the brain.
Brain Neoplasms
Development of a gene/drug dual delivery system for brain tumor therapy: potent inhibition via RNA interference and synergistic effects.
Brain Neoplasms
Differential expression of membrane-type matrix metalloproteinase and its correlation with gelatinase A activation in human malignant brain tumors in vivo and in vitro.
Brain Neoplasms
Dual roles of tumour cells-derived matrix metalloproteinase 2 on brain tumour growth and invasion.
Brain Neoplasms
Expression of matrix metalloproteinases and their inhibitors in human brain tumors.
Brain Neoplasms
Human MT6-matrix metalloproteinase: identification, progelatinase A activation, and expression in brain tumors.
Brain Neoplasms
Identification and characterization of human MT5-MMP, a new membrane-bound activator of progelatinase a overexpressed in brain tumors.
Brain Neoplasms
Inhibition of MMP-2 secretion from brain tumor cells suggests chemopreventive properties of a furanocoumarin glycoside and of chalcones isolated from the twigs of Dorstenia turbinata.
Brain Neoplasms
Matrix metalloproteinase 2 (MMP-2) immunoreactive protein is associated with poor grade and survival in brain neoplasms.
Brain Neoplasms
Matrix metalloproteinase 2 attenuates brain tumour growth, while promoting macrophage recruitment and vascular repair.
Brain Neoplasms
Possible pathophysiological role of vascular endothelial growth factor (VEGF) and matrix metalloproteinases (MMPs) in metastatic brain tumor-associated intracerebral hemorrhage.
Brain Neoplasms
Production of matrix metalloproteinases and tissue inhibitor of metalloproteinases-1 by human brain tumors.
Brain Neoplasms
Specific matrix metalloproteinase profiles in the cerebrospinal fluid correlated with the presence of malignant astrocytomas, brain metastases, and carcinomatous meningitis.
Brain Neoplasms
Targeted delivery of silver nanoparticles and alisertib: in vitro and in vivo synergistic effect against glioblastoma.
Brain Neoplasms
Type IV collagenase activity and cavernous sinus invasion in human pituitary adenomas.
Breast Diseases
Gelatinase-a/mmp-2 serum levels and neoplastic progression in breast-cancer patients.
Breast Diseases
Plasma concentration and activity of matrix metalloproteinase 2 and 9 in patients with breast disease, breast cancer and at risk of developing breast cancer.
Breast Diseases
Sequential activation and production of matrix metalloproteinase-2 during breast cancer progression.
Breast Neoplasms
72 KD and 92 KD type IV collagenase, type IV collagen, and laminin mRNAs in breast cancer: a study by in situ hybridization.
Breast Neoplasms
A fluorescence nanoprobe for detecting the effect of different oxygen and nutrient conditions on breast cancer cells' migration and invasion.
Breast Neoplasms
A high serum matrix metalloproteinase-2 level is associated with an adverse prognosis in node-positive breast carcinoma.
Breast Neoplasms
A novel pathway for mammary epithelial cell invasion induced by the helix-loop-helix protein Id-1.
Breast Neoplasms
A role for endothelial-derived matrix metalloproteinase-2 in breast cancer cell transmigration across the endothelial-basement membrane barrier.
Breast Neoplasms
A single ets-related transcription factor, E1AF, confers invasive phenotype on human cancer cells.
Breast Neoplasms
A stimuli-responsive Janus peptide dendron-drug conjugate as a safe and nanoscale drug delivery vehicle for breast cancer therapy.
Breast Neoplasms
Activated integrin alphavbeta3 cooperates with metalloproteinase MMP-9 in regulating migration of metastatic breast cancer cells.
Breast Neoplasms
Activated Leukocyte Cell Adhesion Molecule (ALCAM) is associated with suppression of breast cancer cells invasion.
Breast Neoplasms
Activation of kinin B1 receptor increases the release of metalloproteases-2 and -9 from both estrogen-sensitive and -insensitive breast cancer cells.
Breast Neoplasms
Activation of matrix metalloproteinase-2 and -9 by 2- and 4-hydroxyestradiol.
Breast Neoplasms
Activation of matrix metalloproteinase-2 by overexpression of manganese superoxide dismutase in human breast cancer MCF-7 cells involves reactive oxygen species.
Breast Neoplasms
Activation of matrix metalloproteinase-2 in human breast cancer cells overexpressing cyclooxygenase-1 or -2.
Breast Neoplasms
Activator Protein-2? Promotes Tumor Growth and Predicts Poor Prognosis in Breast Cancer.
Breast Neoplasms
ADAM 12 cleaves extracellular matrix proteins and correlates with cancer status and stage.
Breast Neoplasms
Aging of stromal-derived human breast fibroblasts might contribute to breast cancer progression.
Breast Neoplasms
An aqueous extract from toad skin prevents gelatinase activities derived from fetal serum albumin and serum-free culture medium of human breast carcinoma MDA-MB-231 cells.
Breast Neoplasms
An Au-Se nanoprobe for the evaluation of the invasive potential of breast cancer cells via imaging the sequential activation of uPA and MMP-2.
Breast Neoplasms
Analysis of the MMP-dependent and independent functions of tissue inhibitor of metalloproteinase-2 on the invasiveness of breast cancer cells.
Breast Neoplasms
Anti-cancer effect of metformin on the metastasis and invasion of primary breast cancer cells through mediating NF-kB activity.
Breast Neoplasms
Anti-cancer effects of Piper nigrum via inducing multiple molecular signaling in vivo and in vitro.
Breast Neoplasms
Apatinib Inhibits Stem Properties and Malignant Biological Behaviors of Breast Cancer Stem Cells by Blocking Wnt/?-catenin Signal Pathway Through Down-regulating LncRNA ROR.
Breast Neoplasms
Apoptotic Induction and Anti-Migratory Effects of Rhazya Stricta Fruit Extracts on a Human Breast Cancer Cell Line.
Breast Neoplasms
Association between Expression of Tissue Inhibitors of Metalloproteinases-1, Matrix Metalloproteinase-2, and Matrix Metalloproteinase-9 Genes and Axillary Lymph Nodes Metastasis in Patients with Breast Cancer.
Breast Neoplasms
Association of cyclooxygenase-2 and matrix metalloproteinase-2 expression in human breast cancer.
Breast Neoplasms
Association of MMP-2 activation potential with metastatic progression in human breast cancer cell lines independent of MMP-2 production.
Breast Neoplasms
Augmentation of type IV collagenase, laminin receptor, and Ki67 proliferation antigen associated with human colon, gastric, and breast carcinoma progression.
Breast Neoplasms
Augmented release of matrix metalloproteinase-9 by PKC activation in organotypic cultures of human breast cancer and adjacent normal breast tissue and fibroadenoma.
Breast Neoplasms
Biomarkers of anticancer activity of R115777 (Tipifarnib, Zarnestra) in human breast cancer models in vitro.
Breast Neoplasms
Bone-Seeking Matrix Metalloproteinase-2 Inhibitors Prevent Bone Metastatic Breast Cancer Growth.
Breast Neoplasms
Breast cancer cell invasion mediated by G?12 signaling involves expression of interleukins-6 and -8, and matrix metalloproteinase-2.
Breast Neoplasms
Brucine suppresses breast cancer metastasis via inhibiting epithelial mesenchymal transition and matrix metalloproteinases expressions.
Breast Neoplasms
C-terminal binding protein-2 promotes cell proliferation and migration in breast cancer via suppression of p16INK4A.
Breast Neoplasms
Calycosin inhibits breast cancer cell migration and invasion by suppressing EMT via BATF/TGF-?1.
Breast Neoplasms
Cancer cell-associated fibronectin induces release of matrix metalloproteinase-2 from normal fibroblasts.
Breast Neoplasms
Cell surface immunophenotype and gelatinase activity of the human breast carcinoma cell line (MCF-7/6) with functionally defective E-cadherin.
Breast Neoplasms
Characterization of a novel, membrane-bound, 80-kDa matrix-degrading protease from human breast cancer cells. Monoclonal antibody production, isolation, and localization.
Breast Neoplasms
Chromodomain Helicase/ATPase DNA-Binding Protein 1-Like Gene (CHD1L) Expression and Implications for Invasion and Metastasis of Breast Cancer.
Breast Neoplasms
Clinical and prognostic role of matrix metalloproteinase-2, -9 and their inhibitors in breast cancer and liver diseases: A review.
Breast Neoplasms
Clinical relevance of cyclooxygenase-2 and matrix metalloproteinases (MMP-2 and MT1-MMP) in human breast cancer tissue.
Breast Neoplasms
Clinical role of MiRNA 29a and MiRNA 335 on breast cancer management: their relevance to MMP2 protein level.
Breast Neoplasms
Clinical significance of matrix metalloproteinase 2 and 9 in breast cancer.
Breast Neoplasms
Clinical significance of plasma MMP-2 and MMP-9 levels as biomarkers for tumor expression in breast cancer patients in Egypt.
Breast Neoplasms
Clinical Study of Tumor Angiogenesis and Perfusion Imaging Using Multi-slice Spiral Computed Tomography for Breast Cancer.
Breast Neoplasms
Clodronate treatment influences MMP-2 associated outcome in node positive breast cancer.
Breast Neoplasms
Cobalt chloride-induced hypoxia modulates the invasive potential and matrix metalloproteinases of primary and metastatic breast cancer cells.
Breast Neoplasms
Common matrix metalloproteinase-2 gene variants and altered susceptibility to breast cancer and associated features in Tunisian women.
Breast Neoplasms
Complex regulation of membrane-type matrix metalloproteinase expression and matrix metalloproteinase-2 activation by concanavalin A in MDA-MB-231 human breast cancer cells.
Breast Neoplasms
Control of lymphatic and hematogenous metastasis of a rat mammary carcinoma by the matrix metalloproteinase inhibitor batimastat (BB-94).
Breast Neoplasms
Correlation between bone scan findings and collagenase activities in patients with breast cancer.
Breast Neoplasms
Correlation between MMPs and their inhibitors in breast cancer tumor tissue specimens and in cell lines with different metastatic potential.
Breast Neoplasms
Correlation of tissue inhibitor of metalloproteinase-2 with proliferative activity and patients' survival in breast cancer.
Breast Neoplasms
Current evidence on the relationship between four polymorphisms in the matrix metalloproteinases (MMP) gene and breast cancer risk: a meta-analysis.
Breast Neoplasms
Daidzein, R-(+)equol and S-(-)equol inhibit the invasion of MDA-MB-231 breast cancer cells potentially via the down-regulation of matrix metalloproteinase-2.
Breast Neoplasms
Degradation of HER2/neu by ANT2 shRNA suppresses migration and invasiveness of breast cancer cells.
Breast Neoplasms
Differential regulation of matrix metalloproteinase-2 activation in human breast cancer cell lines.
Breast Neoplasms
Downregulation of miR-106b induced breast cancer cell invasion and motility in association with overexpression of matrix metalloproteinase 2.
Breast Neoplasms
Doxorubicin conjugated with a trastuzumab epitope and an MMP-2 sensitive peptide linker for the treatment of HER2-positive breast cancer.
Breast Neoplasms
Effect of bevacizumab combined with docetaxel in the treatment of HER-2-negative recurrent metastatic breast cancer.
Breast Neoplasms
Effect of methanolic and water extract of Leucobryum bowringii Mitt. on growth, migration and invasion of MCF 7 human breast cancer cells in vitro.
Breast Neoplasms
Effect of microRNA-206 on cytoskeleton remodelling by downregulating Cdc42 in MDA-MB-231 cells.
Breast Neoplasms
Effect of MMP-2 gene silencing on radiation-induced DNA damage in human normal dermal fibroblasts and breast cancer cells.
Breast Neoplasms
Effect of phorbol ester and cytokines on matrix metalloproteinase and tissue inhibitor of metalloproteinase expression in tumor and normal cell lines.
Breast Neoplasms
Effect of Sirtuin 1 inhibition on matrix metalloproteinase 2 and Forkhead box O3a expression in breast cancer cells.
Breast Neoplasms
Effects of doxycycline on in vitro growth, migration, and gelatinase activity of breast carcinoma cells.
Breast Neoplasms
Effects of Lidocaine and Src Inhibition on Metastasis in a Murine Model of Breast Cancer Surgery.
Breast Neoplasms
Effects of linoleic acid on the growth and metastasis of two human breast cancer cell lines in nude mice and the invasive capacity of these cell lines in vitro.
Breast Neoplasms
Effects of specific DNMT-gene depletion on cancer cell transformation and breast cancer cell invasion; towards selective DNMT inhibitors.
Breast Neoplasms
Eicosanoids as mediators of linoleic acid-stimulated invasion and type IV collagenase production by a metastatic human breast cancer cell line.
Breast Neoplasms
Elevated cyclic AMP suppresses ConA-induced MT1-MMP expression in MDA-MB-231 human breast cancer cells.
Breast Neoplasms
Elevated expression of both MDR1 and MMP-2 genes in metastasized lymph node of invasive ductal breast cancer.
Breast Neoplasms
Enhanced expression of tissue inhibitor of metalloproteinase-2 (TIMP-2) in the stroma of breast carcinomas correlates with tumor recurrence.
Breast Neoplasms
Enhancing effect of platelet-derived microvesicles on the invasive potential of breast cancer cells.
Breast Neoplasms
Epidermal growth factor and amphiregulin up-regulate matrix metalloproteinase-9 (MMP-9) in human breast cancer cells.
Breast Neoplasms
Epidermal growth factor receptor-mediated regulation of matrix metalloproteinase-2 and matrix metalloproteinase-9 in MCF-7 breast cancer cells.
Breast Neoplasms
Epigenetic Control of the Invasion-promoting MT1-MMP/MMP-2/TIMP-2 Axis in Cancer Cells.
Breast Neoplasms
Epigenetic induction of tissue inhibitor of matrix metalloproteinase-3 by green tea polyphenols in breast cancer cells.
Breast Neoplasms
Ethanol-induced in vitro invasion of breast cancer cells: the contribution of MMP-2 by fibroblasts.
Breast Neoplasms
Ethyl gallate suppresses proliferation and invasion in human breast cancer cells via Akt-NF-?B signaling.
Breast Neoplasms
Evaluation of Matrix Metalloproteinase-2 (MMP-2) Activity with Film in situ Zymography for Improved Cytological Diagnosis of Breast Tumors.
Breast Neoplasms
Ex-FABP: a fatty acid binding lipocalin developmentally regulated in chicken endochondral bone formation and myogenesis.
Breast Neoplasms
Exogenous coenzyme Q10 modulates MMP-2 activity in MCF-7 cell line as a breast cancer cellular model.
Breast Neoplasms
Expression of Alpha-Enolase (ENO1), Myc Promoter-Binding Protein-1 (MBP-1) and Matrix Metalloproteinases (MMP-2 and MMP-9) Reflect the Nature and Aggressiveness of Breast Tumors.
Breast Neoplasms
Expression of E-cadherin, beta-catenin, cathepsin D, gelatinases and their inhibitors in invasive ductal breast carcinomas.
Breast Neoplasms
Expression of gelatinases A and B, stromelysin-3 and matrilysin genes in breast carcinomas: clinico-pathological correlations.
Breast Neoplasms
Expression of matrix metalloproteinase (MMP)-2 and MMP-9 in breast cancer with a special reference to activator protein-2, HER2, and prognosis.
Breast Neoplasms
Expression of matrix metalloproteinase 2 and 9 in breast cancer and breast fibroadenoma: a randomized, double-blind study.
Breast Neoplasms
Expression of matrix metalloproteinase-26 in multiple human cancer tissues and smooth muscle cells.
Breast Neoplasms
Expression of metalloproteinases MMP-2 and MMP-9 in sentinel lymph node and serum of patients with metastatic and non-metastatic breast cancer.
Breast Neoplasms
Expression of MiR-335 and its target metalloproteinase genes: clinical significance in breast cancer.
Breast Neoplasms
Expression of MMP-2 and MMP-9, their inhibitors, and the activator MT1-MMP in primary breast carcinomas.
Breast Neoplasms
Expression of MMP2, MMP9 and MMP3 in breast cancer brain metastasis in a rat model.
Breast Neoplasms
Expression of mRNA for gelatinase A and TIMP-2 in cell cultures and tissue samples derived from breast and lung carcinomas.
Breast Neoplasms
Expression of neurotensin and NT1 receptor in human breast cancer: a potential role in tumor progression.
Breast Neoplasms
Expression of nm23, MMP-2, TIMP-2 in breast neoplasm in Zhengzhou Center Hospital, China.
Breast Neoplasms
Expression of PEA3/E1AF/ETV4, an Ets-related transcription factor, in breast tumors: positive links to MMP2, NRG1 and CGB expression.
Breast Neoplasms
Expression of proteinases and inhibitors in human breast cancer progression and survival.
Breast Neoplasms
Expression of tissue inhibitor of metalloproteinase-1 and type IV collagenase/gelatinase messenger RNAs in human breast cancer.
Breast Neoplasms
Expression of tissue levels of matrix metalloproteinases and their inhibitors in breast cancer.
Breast Neoplasms
Expression patterns of stromal MMP-2 and tumoural MMP-2 and -9 are significant prognostic factors in invasive ductal carcinoma of the breast.
Breast Neoplasms
Extracellular heat shock protein (Hsp)70 and Hsp90? assist in matrix metalloproteinase-2 activation and breast cancer cell migration and invasion.
Breast Neoplasms
Ezrin-Radixin-Moesin Binding Phosphoprotein 50 (EBP50) Suppresses the Metastasis of Breast Cancer and HeLa Cells by Inhibiting Matrix Metalloproteinase-2 Activity.
Breast Neoplasms
Fibronectin affects transient MMP2 gene expression through DNA demethylation changes in non-invasive breast cancer cell lines.
Breast Neoplasms
Formononetin Inhibits Migration and Invasion of MDA-MB-231 and 4T1 Breast Cancer Cells by Suppressing MMP-2 and MMP-9 Through PI3K/AKT Signaling Pathways.
Breast Neoplasms
Fucosyltransferase 8 deficiency suppresses breast cancer cell migration by interference of the FAK/integrin pathway.
Breast Neoplasms
Galectin-3 is a novel substrate for human matrix metalloproteinases-2 and -9.
Breast Neoplasms
GALNT14 mediates tumor invasion and migration in breast cancer cell MCF-7.
Breast Neoplasms
Gelatin zymography and substrate cleavage assays of matrix metalloproteinase-2 in breast carcinoma cells overexpressing membrane type-1 matrix metalloproteinase.
Breast Neoplasms
Gelatinase A expression and localization in human breast cancers. An in situ hybridization study and immunohistochemical detection using confocal microscopy.
Breast Neoplasms
Gelatinase A, membrane type 1 matrix metalloproteinase, and extracellular matrix metalloproteinase inducer mRNA expression: correlation with invasive growth of breast cancer.
Breast Neoplasms
Gelatinase A/TIMP-2 imbalance in lymph-node-positive breast carcinomas, as measured by RT-PCR.
Breast Neoplasms
Gelatinase concentrations and zymographic profiles in human breast cancer: matrix metalloproteinases circulating in plasma are better markers for the subclassification and early prediction of cancer: the coagulation/fibrinolysis pathways alter the release, activation and recovery of different gelatinases in serum.
Breast Neoplasms
Gelatinase-a/mmp-2 serum levels and neoplastic progression in breast-cancer patients.
Breast Neoplasms
Gene Polymorphisms and Circulating Levels of MMP-2 and MMP-9: A Review of Their Role in Breast Cancer Risk.
Breast Neoplasms
Genetic polymorphisms in the MMP-2 and MMP-9 genes and breast cancer phenotype.
Breast Neoplasms
Genetic polymorphisms of matrix metalloproteinases in lung, breast and colorectal cancer.
Breast Neoplasms
Genistein suppresses the invasive potential of human breast cancer cells through transcriptional regulation of metalloproteinases and their tissue inhibitors.
Breast Neoplasms
HIF-2? as a prognostic marker for breast cancer progression and patient survival.
Breast Neoplasms
How ADAM-9 and ADAM-11 differentially from estrogen receptor predict response to tamoxifen treatment in patients with recurrent breast cancer: a retrospective study.
Breast Neoplasms
Human brain endothelial cell-derived COX-2 facilitates extravasation of breast cancer cells across the blood-brain barrier.
Breast Neoplasms
Hypoxia stimulates breast carcinoma cell invasion through MT1-MMP and MMP-2 activation.
Breast Neoplasms
Identification and characterization of a novel matrix-degrading protease from hormone-dependent human breast cancer cells.
Breast Neoplasms
Identification of Caspase-6 as a New Regulator of Alternatively Activated Macrophages.
Breast Neoplasms
Identification of the functional role of AF1Q in the progression of breast cancer.
Breast Neoplasms
Immunolocalization of matrix metallo-proteinases and their tissue inhibitor in human mammary pathology.
Breast Neoplasms
Immunological characterization of cell-surface and soluble forms of membrane type 1 matrix metalloproteinase in human breast cancer cells and in fibroblasts.
Breast Neoplasms
Implication of alpha5beta1 integrin in invasion of drug-resistant MCF-7/ADR breast carcinoma cells: a role for MMP-2 collagenase.
Breast Neoplasms
Implication of collagen type I-induced membrane-type 1-matrix metalloproteinase expression and matrix metalloproteinase-2 activation in the metastatic progression of breast carcinoma.
Breast Neoplasms
In vitro and in vivo antitumorigenic activity of a mixture of lysine, proline, ascorbic acid, and green tea extract on human breast cancer lines MDA-MB-231 and MCF-7.
Breast Neoplasms
Increase in tissue inhibitor of metalloproteinase-2 (TIMP-2) levels and inhibition of MMP-2 activity in a metastatic breast cancer cell line by an anti-invasive small molecule SR13179.
Breast Neoplasms
Increased expression of CYP4Z1 promotes tumor angiogenesis and growth in human breast cancer.
Breast Neoplasms
Increased gelatinase-A and gelatinase-B activities in malignant vs. benign breast tumors.
Breast Neoplasms
Increased invasive potential and up-regulation of MMP-2 in MDA-MB-231 breast cancer cells expressing the beta3 integrin subunit.
Breast Neoplasms
Indole-3-carbinol inhibits Sp1-induced matrix metalloproteinase-2 expression to attenuate migration and invasion of breast cancer cells.
Breast Neoplasms
Induction of matrix metalloproteinases MMP-1 and MMP-2 by co-culture of breast cancer cells and bone marrow fibroblasts.
Breast Neoplasms
Inhibition of breast cancer cell extracellular matrix degradative activity by chemically modified tetracyclines.
Breast Neoplasms
Inhibition of matrix metalloproteinase-2 by halofuginone is mediated by the Egr1 transcription factor.
Breast Neoplasms
Inhibition of Metastatic Tumor Growth and Metastasis via Targeting Metastatic Breast Cancer by Chlorotoxin-Modified Liposomes.
Breast Neoplasms
Inhibition of MT1-MMP proteolytic function and ERK1/2 signalling influences cell migration and invasion through changes in MMP-2 and MMP-9 levels.
Breast Neoplasms
Inhibition of osteolytic bone metastasis of breast cancer by combined treatment with the bisphosphonate ibandronate and tissue inhibitor of the matrix metalloproteinase-2.
Breast Neoplasms
Inhibitory effect of emodin on migration, invasion and metastasis of human breast cancer MDA-MB-231 cells in vitro and in vivo.
Breast Neoplasms
Integrin alpha5beta1 controls invasion of human breast carcinoma cells by direct and indirect modulation of MMP-2 collagenase activity.
Breast Neoplasms
Integrin-linked kinase regulates osteopontin-dependent MMP-2 and uPA expression to convey metastatic function in murine mammary epithelial cancer cells.
Breast Neoplasms
Interaction between CD147 and P-glycoprotein and their regulation by ubiquitination in breast cancer cells.
Breast Neoplasms
Invasiveness of breast cancer cells MDA-MB-231 through extracellular matrix is increased by the estradiol metabolite 4-hydroxyestradiol.
Breast Neoplasms
Involvement of matrix metalloproteinase 2 and 9 in gambogic acid induced suppression of MDA-MB-435 human breast carcinoma cell lung metastasis.
Breast Neoplasms
Irradiation of normal mouse tissue increases the invasiveness of mammary cancer cells.
Breast Neoplasms
Knockdown of hypoxia inducible factor-2? inhibits cell invasion via the downregulation of MMP-2 expression in breast cancer cells.
Breast Neoplasms
Lack of association between the matrix metalloproteinase-2 -1306C>T polymorphism and breast cancer susceptibility: a meta-analysis.
Breast Neoplasms
LASS2/TMSG1 inhibits growth and invasion of breast cancer cell in vitro through regulation of vacuolar ATPase activity.
Breast Neoplasms
Leptin utilizes Jun N-terminal kinases to stimulate the invasion of MCF-7 breast cancer cells.
Breast Neoplasms
Localization of gelatinolytic activity can be detected in breast cancer tissues by film in situ zymography.
Breast Neoplasms
Localization of TFPI-2 in the nucleus modulates MMP-2 gene expression in breast cancer cells.
Breast Neoplasms
Locally advanced breast carcinoma treated with neoadjuvant chemotherapy: are the changes in serum levels of YKL-40, MMP-2 and MMP-9 correlated with tumor response?
Breast Neoplasms
Low serum level of pro-matrix metalloproteinase 2 correlates with aggressive behavior in breast carcinoma.
Breast Neoplasms
Low-volume multiplexed proteolytic activity assay and inhibitor analysis through a pico-injector array.
Breast Neoplasms
Lycorine inhibits the growth and metastasis of breast cancer through the blockage of STAT3 signaling pathway.
Breast Neoplasms
M(r) 92,000 type IV collagenase is increased in plasma of patients with colon cancer and breast cancer.
Breast Neoplasms
Matrix metalloproteinase-2 (MMP-2) is associated with survival in breast carcinoma.
Breast Neoplasms
Matrix metalloproteinase-2 (MMP-2) is associated with the risk for a relapse in postmenopausal patients with node-positive breast carcinoma treated with antiestrogen adjuvant therapy.
Breast Neoplasms
Matrix metalloproteinase-2 C(-1306)T promoter polymorphism and breast cancer risk in the Saudi population.
Breast Neoplasms
Matrix metalloproteinase-2 immunoreactive protein: a marker of aggressiveness in breast carcinoma.
Breast Neoplasms
Matrix metalloproteinase-2 involvement in breast cancer progression: a mini-review.
Breast Neoplasms
Matrix metalloproteinase-2 polymorphisms and breast cancer susceptibility.
Breast Neoplasms
Matrix Metalloproteinase-2 Promoter Polymorphism Is Associated with Breast Cancer in a Mexican Population.
Breast Neoplasms
Matrix metalloproteinase-2: A key regulator in coagulation proteases mediated human breast cancer progression through autocrine signaling.
Breast Neoplasms
Matrix Metalloproteinase-9 -1562T Allele and its Combination with MMP-2 -735 C Allele are Risk Factors for Breast Cancer.
Breast Neoplasms
Matrix metalloproteinases in neoplasm-induced extracellular matrix remodeling in breast carcinomas.
Breast Neoplasms
MEKK1 controls matrix degradation and tumor cell dissemination during metastasis of polyoma middle-T driven mammary cancer.
Breast Neoplasms
Membrane-type matrix metalloproteinase (MT-MMP) gene is expressed in stromal cells of human colon, breast, and head and neck carcinomas.
Breast Neoplasms
Meta-analysis on the relationship between the SNP of MMP-2-1306 C>T and susceptibility to breast cancer.
Breast Neoplasms
Metalloproteinases 1 and 3 as Potential Biomarkers in Breast Cancer Development.
Breast Neoplasms
MMP-2 -1306C>T polymorphism in breast cancer: a case-control study in a South European population.
Breast Neoplasms
MMP-2 and MMP-9 activity is regulated by estradiol and tamoxifen in cultured human breast cancer cells.
Breast Neoplasms
MMP-2 and MMP-9 expression in breast cancer-derived human fibroblasts is differentially regulated by stromal-epithelial interactions.
Breast Neoplasms
MMP-2 positivity and age less than 40 years increases the risk for recurrence in premenopausal patients with node-positive breast carcinoma.
Breast Neoplasms
MMP-2 protein in invasive breast cancer and the impact of MMP-2/TIMP-2 phenotype on overall survival.
Breast Neoplasms
MMP-2, MMP-9 and activin A blood levels in patients with breast cancer or prostate cancer metastatic to the bone.
Breast Neoplasms
MMP-9 and MMP-2 gelatinases and TIMP-1 and TIMP-2 inhibitors in breast cancer: correlations with prognostic factors.
Breast Neoplasms
MMP-9 secretion and MMP-2 activation distinguish invasive and metastatic sublines of a mouse mammary carcinoma system showing epithelial-mesenchymal transition traits.
Breast Neoplasms
MMP2 role in breast cancer brain metastasis development and its regulation by TIMP2 and ERK1/2.
Breast Neoplasms
Momordica cochinchinensis Seed Extracts Suppress Migration and Invasion of Human Breast Cancer ZR-75-30 Cells Via Down-regulating MMP-2 and MMP-9.
Breast Neoplasms
Monensin inhibits proliferation, migration, and promotes apoptosis of breast cancer cells via downregulating UBA2.
Breast Neoplasms
MT1-MMP correlates with MMP-2 activation potential seen after epithelial to mesenchymal transition in human breast carcinoma cells.
Breast Neoplasms
MT1-MMP initiates activation of pro-MMP-2 and integrin alphavbeta3 promotes maturation of MMP-2 in breast carcinoma cells.
Breast Neoplasms
Multifunctional effect of epigallocatechin-3-gallate (EGCG) in downregulation of gelatinase-A (MMP-2) in human breast cancer cell line MCF-7.
Breast Neoplasms
Mutation analysis of membrane type-1 matrix metalloproteinase (MT1-MMP). The role of the cytoplasmic tail Cys(574), the active site Glu(240), and furin cleavage motifs in oligomerization, processing, and self-proteolysis of MT1-MMP expressed in breast carcinoma cells.
Breast Neoplasms
Neurokinin-1 receptor mediated breast cancer cell migration by increased expression of MMP-2 and MMP-14.
Breast Neoplasms
New Insights into the Occurrence of Matrix Metalloproteases -2 and -9 in a Cohort of Breast Cancer Patients and Proteomic Correlations.
Breast Neoplasms
New pathway links from cancer-progression determinants to gene expression of matrix metalloproteinases in breast cancer cells.
Breast Neoplasms
Novel ternary vanadium-betaine-peroxido species suppresses H-ras and matrix metalloproteinase-2 expression by increasing reactive oxygen species-mediated apoptosis in cancer cells.
Breast Neoplasms
NRF3 suppresses breast cancer cell metastasis and cell proliferation and is a favorable predictor of survival in breast cancer.
Breast Neoplasms
Ocimum gratissimum retards breast cancer growth and progression and is a natural inhibitor of matrix metalloproteases.
Breast Neoplasms
Oncological Risk in Autologous Stem Cell Donation for Novel Tissue-Engineering Approaches to Postmastectomy Breast Regeneration.
Breast Neoplasms
Overexpression of MMP Family Members Functions as Prognostic Biomarker for Breast Cancer Patients: A Systematic Review and Meta-Analysis.
Breast Neoplasms
Patients with hepatic breast cancer metastases demonstrate highly specific profiles of matrix metalloproteinases MMP-2 and MMP-9 after SIRT treatment as compared to other primary and secondary liver tumours.
Breast Neoplasms
Pattern of collagen fibers and localization of matrix metalloproteinase 2 and 9 during breast cancer invasion.
Breast Neoplasms
Phosphocitrate inhibits calcium hydroxyapatite induced mitogenesis and upregulation of matrix metalloproteinase-1, interleukin-1beta and cyclooxygenase-2 mRNA in human breast cancer cell lines.
Breast Neoplasms
Photothermal/matrix metalloproteinase-2 dual-responsive gelatin nanoparticles for breast cancer treatment.
Breast Neoplasms
Physical exercise modulates the level of serum MMP-2 and MMP-9 in patients with breast cancer.
Breast Neoplasms
Plantamajoside, a potential anti-tumor herbal medicine inhibits breast cancer growth and pulmonary metastasis by decreasing the activity of matrix metalloproteinase-9 and -2.
Breast Neoplasms
Plasma concentration and activity of matrix metalloproteinase 2 and 9 in patients with breast disease, breast cancer and at risk of developing breast cancer.
Breast Neoplasms
Plasma gelatinase levels in patients with primary breast cancer in relation to axillary lymph node status, Her2/neu expression and other clinicopathological variables.
Breast Neoplasms
Plasma Levels and Diagnostic Utility of M-CSF, MMP-2 and its Inhibitor TIMP-2 in the Diagnostics of Breast Cancer Patients.
Breast Neoplasms
Plasma levels and diagnostic utility of VEGF, MMP-2 and TIMP-2 in the diagnostics of breast cancer patients.
Breast Neoplasms
Plasma levels of matrix metalloproteinases 2 and 9 correlate with histological grade in breast cancer patients.
Breast Neoplasms
Platelet derived growth factor increases phospholipase D1 but not phospholipase D2 expression via NFkappaB signaling pathway and enhances invasion of breast cancer cells.
Breast Neoplasms
Polymorphisms of matrix metalloproteinases 1, 2, 3 and 9 and susceptibility to lung, breast and colorectal cancer in over 30,000 subjects.
Breast Neoplasms
Polyphenols from Artemisia annua L Inhibit Adhesion and EMT of Highly Metastatic Breast Cancer Cells MDA-MB-231.
Breast Neoplasms
Potential of fluorescent metalloproteinase substrates for cancer detection.
Breast Neoplasms
Preoperative Serum Levels of Matrix Metalloproteinase-2 (MMP-2) and Survival of Breast Cancer among Korean Women.
Breast Neoplasms
Prevalence of vascular-endothelial growth factor, matrix metalloproteinases and tissue inhibitors of metalloproteinases in primary breast cancer.
Breast Neoplasms
Pro-matrix metalloproteinase-2 transfection increases orthotopic primary growth and experimental metastasis of MDA-MB-231 human breast cancer cells in nude mice.
Breast Neoplasms
Production of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human breast carcinomas.
Breast Neoplasms
Prognostic impact of polymorphism of matrix metalloproteinase-2 and metalloproteinase tissue inhibitor-2 promoters in breast cancer in Tunisia: case-control study.
Breast Neoplasms
Prognostic significance of stromelysin 3, gelatinase A, and urokinase expression in breast cancer.
Breast Neoplasms
Prognostic value of matrix metalloproteinase-2 (MMP-2), matrix metalloproteinase-9 (MMP-9) and aminopeptidase N/CD13 in breast cancer patients.
Breast Neoplasms
Prognostic value of matrix metalloproteinases (MMP-2 and MMP-9) in patients with lymph node-negative breast carcinoma.
Breast Neoplasms
Prognostic values of ETS-1, MMP-2 and MMP-9 expression and co-expression in breast cancer patients.
Breast Neoplasms
Propoxur enhances MMP-2 expression and the corresponding invasion of human breast cancer cells via the ERK/Nrf2 signaling pathway.
Breast Neoplasms
Protein kinase D1 regulates matrix metalloproteinase expression and inhibits breast cancer cell invasion.
Breast Neoplasms
Purification and characterization of bioactive his6-tagged recombinant human tissue inhibitor of metalloproteinases-1 (TIMP-1) protein expressed at high yields in mammalian cells.
Breast Neoplasms
Quantitatively Visualizing Tumor-Related Protease Activity in Vivo Using a Ratiometric Photoacoustic Probe.
Breast Neoplasms
Rapid expression and activation of MMP-2 and MMP-9 upon exposure of human breast cancer cells (MCF-7) to fibronectin in serum free medium.
Breast Neoplasms
Realgar Nanoparticles Inhibit Migration, Invasion and Metastasis in a Mouse Model of Breast Cancer by Suppressing Matrix Metalloproteinases and Angiogenesis.
Breast Neoplasms
Reciprocal effects of ascorbate on cancer cell growth and the expression of matrix metalloproteinases and transforming growth factor-beta.
Breast Neoplasms
Reduced expression of Snail decreases breast cancer cell motility by downregulating the expression and inhibiting the activity of RhoA GTPase.
Breast Neoplasms
Regulation of MMP-1 and MMP-2 production through CD147/extracellular matrix metalloproteinase inducer interactions.
Breast Neoplasms
Relationship between matrix metalloproteinase expression and tumor angiogenesis in human breast carcinoma.
Breast Neoplasms
Relationships Between Immunophenotype, Ki-67 Index, Microvascular Density, Ep-CAM/P-cadherin, and MMP-2 Expression in Early-stage Invasive Ductal Breast Cancer.
Breast Neoplasms
Relationships between the level of matrix metalloproteinase-2 and tumor size of breast cancer.
Breast Neoplasms
Requirements for estrogen receptor alpha membrane localization and function.
Breast Neoplasms
Restricted expression of membrane type 1-matrix metalloproteinase by myofibroblasts adjacent to human breast cancer cells.
Breast Neoplasms
Role of DDR1 in the gelatinases secretion induced by native type IV collagen in MDA-MB-231 breast cancer cells.
Breast Neoplasms
Role of matrix metalloproteinase-2 in ethanol-induced invasion by breast cancer cells.
Breast Neoplasms
Role of PTHrp and PTHrp-engaged pathways in MCF-7 cells migration/invasion.
Breast Neoplasms
Role of serum matrix metalloproteinase-2 and -9 to predict breast cancer progression.
Breast Neoplasms
Salinomycin suppresses TGF-?1-induced epithelial-to-mesenchymal transition in MCF-7 human breast cancer cells.
Breast Neoplasms
Self-assembled nanomedicine combining a berberine derivative and doxorubicin for enhanced antitumor and antimetastatic efficacy via mitochondrial pathways.
Breast Neoplasms
Sequential activation and production of matrix metalloproteinase-2 during breast cancer progression.
Breast Neoplasms
Serum levels of matrix metalloproteinase 2 in patients with breast cancer.
Breast Neoplasms
Serum levels of matrix metalloproteinase-9 predict lymph node metastasis in breast cancer patients.
Breast Neoplasms
Serum levels of matrix metalloproteinases MMP-2 and MMP-9 and their tissue natural inhibitors in breast tumors.
Breast Neoplasms
Silencing of KIF3B Suppresses Breast Cancer Progression by Regulating EMT and Wnt/?-Catenin Signaling.
Breast Neoplasms
Silencing of TMSG1 enhances metastasis capacity by targeting V-ATPase in breast cancer.
Breast Neoplasms
Snail, Slug, and Smad-interacting protein 1 as novel parameters of disease aggressiveness in metastatic ovarian and breast carcinoma.
Breast Neoplasms
SPARC/osteonectin induces matrix metalloproteinase 2 activation in human breast cancer cell lines.
Breast Neoplasms
Stimulation of type IV collagenase expression by linoleic acid in a metastatic human breast cancer cell line.
Breast Neoplasms
Stromal expression of matrix metalloproteinase 2 in cancer-associated fibroblasts is strongly related to human epidermal growth factor receptor 2 status in invasive breast carcinoma.
Breast Neoplasms
Stromelysin 3 belongs to a subgroup of proteinases expressed in breast carcinoma fibroblastic cells and possibly implicated in tumor progression.
Breast Neoplasms
Stromelysin-3 mRNA expression and malignancy: comparison with clinicopathological features and type IV collagenase mRNA expression in breast tumors.
Breast Neoplasms
Studies on Multifunctional Effect of All-Trans Retinoic Acid (ATRA) on Matrix Metalloproteinase-2 (MMP-2) and Its Regulatory Molecules in Human Breast Cancer Cells (MCF-7).
Breast Neoplasms
Substantial reduction in risk of breast cancer associated with genetic polymorphisms in the promoters of the matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 genes.
Breast Neoplasms
Sulforaphene Interferes with Human Breast Cancer Cell Migration and Invasion through Inhibition of Hedgehog Signaling.
Breast Neoplasms
Super Magnetic Niosomal Nanocarrier as a New Approach for Treatment of Breast Cancer: A Case Study on SK-BR-3 and MDA-MB-231 Cell Lines.
Breast Neoplasms
Suppression of growth, migration and invasion of highly-metastatic human breast cancer cells by berbamine and its molecular mechanisms of action.
Breast Neoplasms
Suppression of type IV collagenase in MDA-MB-435 human breast cancer cells by eicosapentaenoic acid in vitro and in vivo.
Breast Neoplasms
Suppressive Effects of Plumbagin on Invasion and Migration of Breast Cancer Cells via the Inhibition of STAT3 Signaling and Down-regulation of Inflammatory Cytokine Expressions.
Breast Neoplasms
Synthesis, characterization and in vitro study of biocompatible cinnamaldehyde functionalized magnetite nanoparticles (CPGF Nps) for hyperthermia and drug delivery applications in breast cancer.
Breast Neoplasms
The AIB1 oncogene promotes breast cancer metastasis by activation of PEA3-mediated matrix metalloproteinase 2 (MMP2) and MMP9 expression.
Breast Neoplasms
The Anti-tumoral Effect of ?-D-Mannuronic Acid (M2000) as a Novel NSAID on Treg Cells Frequency and MMP-2, MMP-9, CCL22 and TGF?1 Gene Expression in Pre-surgical Breast Cancer Patients.
Breast Neoplasms
The Difference of Expression of 18 Genes in Axillary Invasion and Vascular Invasion Compared to Control Samples in Breast Cancer.
Breast Neoplasms
The Effect of Chrysin Loaded PLGA-PEG on Metalloproteinase Gene Expression in Mouse 4T1 Tumor Model.
Breast Neoplasms
The Effects of Houttuynia cordata Thunb and Piper ribesioides Wall Extracts on Breast Carcinoma Cell Proliferation, Migration, Invasion and Apoptosis.
Breast Neoplasms
The EphB4 receptor suppresses breast cancer cell tumorigenicity through an Abl-Crk pathway.
Breast Neoplasms
The G(12) family proteins upregulate matrix metalloproteinase-2 via p53 leading to human breast cell invasion.
Breast Neoplasms
The impact of matrix metalloproteinase 2 on prognosis and clinicopathology of breast cancer patients: a systematic meta-analysis.
Breast Neoplasms
The influence of MMP-14, TIMP-2 and MMP-2 expression on breast cancer prognosis.
Breast Neoplasms
The influence of opioids on matrix metalloproteinase-2 and -9 secretion and mRNA levels in MCF-7 breast cancer cell line.
Breast Neoplasms
The level of serum pro-matrix metalloproteinase-2 as a prognostic factor in patients with invasive ductal breast cancer.
Breast Neoplasms
The MMP-2 -735 C allele is a risk factor for susceptibility to breast cancer.
Breast Neoplasms
The Protein Extract of Chlorella minutissima Inhibits The Expression of MMP-1, MMP-2 and MMP-9 in Cancer Cells through Upregulation of TIMP-3 and Down Regulation of c-Jun.
Breast Neoplasms
The relationship between MMP-2 and MMP-9 expression levels with breast cancer incidence and prognosis.
Breast Neoplasms
The TGF-beta/Smad pathway induces breast cancer cell invasion through the up-regulation of matrix metalloproteinase 2 and 9 in a spheroid invasion model system.
Breast Neoplasms
The type I collagen induction of MT1-MMP-mediated MMP-2 activation is repressed by alphaVbeta3 integrin in human breast cancer cells.
Breast Neoplasms
Tissue distribution of major matrix metalloproteinases and their transcripts in human breast carcinomas.
Breast Neoplasms
Tissue inhibitor of metalloproteinase-2 regulates matrix metalloproteinase-2-mediated endothelial barrier dysfunction and breast cancer cell transmigration through lung microvascular endothelial cells.
Breast Neoplasms
Tumor cell invasion through matrigel is regulated by activated matrix metalloproteinase-2.
Breast Neoplasms
Tumor cell specific expression of MMP-2 correlates with tumor vascularisation in breast cancer.
Breast Neoplasms
Tumor grade and matrix metalloproteinase 2 expression in stromal fibroblasts help to stratify the high-risk group of patients with early breast cancer identified on the basis of st gallen recommendations.
Breast Neoplasms
Tumor-derived matrix metalloproteinase-13 (MMP-13) correlates with poor prognoses of invasive breast cancer.
Breast Neoplasms
Tumour-associated fibrinolysis: the prognostic relevance of plasminogen activators uPA and tPA in human breast cancer.
Breast Neoplasms
Tyrosine phosphorylation mediates ConA-induced membrane type 1-matrix metalloproteinase expression and matrix metalloproteinase-2 activation in MDA-MB-231 human breast carcinoma cells.
Breast Neoplasms
Unifloral ajwain honey ameliorates differential inhibition of matrix metalloproteinases 2 and 9 protein, cytotoxicity, and antioxidant potential.
Breast Neoplasms
Up-regulation of CD147 and matrix metalloproteinase-2, -9 induced by P-glycoprotein substrates in multidrug resistant breast cancer cells.
Breast Neoplasms
Upregulation of VEGF-A and CD24 gene expression by the tGLI1 transcription factor contributes to the aggressive behavior of breast cancer cells.
Breast Neoplasms
Values of MMP-2 and MMP-9 in Tumor Tissue of Basal-Like Breast Cancer Patients.
Breast Neoplasms
Violacein inhibits matrix metalloproteinase mediated CXCR4 expression: potential anti-tumor effect in cancer invasion and metastasis.
Breast Neoplasms
Vitamin D, tamoxifen and beta-estradiol modulate breast cancer cell growth and interleukin-6 and metalloproteinase-2 production in three-dimensional co-cultures of tumor cell spheroids with endothelium.
Breast Neoplasms
Worse prognosis in breast cancer patients can be predicted by immunohistochemical analysis of positive MMP-2 and negative estrogen and progesterone receptors.
Breast Neoplasms
Zymographic detection and clinical correlations of MMP-2 and MMP-9 in breast cancer sera.
Breast Neoplasms
[Association of JMJD3, MMP-2 and VEGF expressions with clinicopathological features of invasive ductal breast carcinoma].
Breast Neoplasms
[Clinical significance and relationship of expression of matrix metalloproteinase-2 mRNA with breast cancer metastasis.]
Breast Neoplasms
[Effect of ethyl gallate on invasion abilities and its mechanism of breast cancer MDA-MB-231 cells].
Breast Neoplasms
[Effect of lupeol on migration and invasion of human breast cancer MDA-MB-231 cells and its mechanism].
Breast Neoplasms
[Effects of Se-methylselenocysteine on Biological Behavior of and Matrix Metalloproteinase-2 Expression in Human Breast Cancer MDA-MB-231 Cells.]
Breast Neoplasms
[Expression and clinical significance of MMP-2, MMP-9,TIMP-1, and TIMP-2 in breast carcinoma]
Breast Neoplasms
[Expression of CD147, matrix metalloproteinases and transforming growth factor beta1 in breast cancer]
Breast Neoplasms
[Expression of matrix metalloproteinase (MMP-2) and extracellular matrix metalloproteinases inducer (EMMPRIN) in benign and advanced breast cancer tissue samples]
Breast Neoplasms
[Expression of TGF-beta1 and the mechanism of invasiveness and metastasis induced by TGF-beta1 in breast cancer]
Breast Neoplasms
[Expressions of CD147 and matrix metalloproteinase-2 in breast cancer and their correlations to prognosis]
Breast Neoplasms
[Inhibitory effect of luteolin on the angiogenesis of chick chorioallantoic membrane and invasion of breast cancer cells via downregulation of AEG-1 and MMP-2].
Breast Neoplasms
[Relationship between the expression of matrix metalloproteinase-13 protein and other biomarkers, prognosis in invasive breast cancer]
Breast Neoplasms
[Role of matrix metalloproteinase (MMP)-2 and -9 and vascular endothelial growth factor C in lymph node metastasis of breast cancer.]
Breast Neoplasms
[Serum level of MMP-2 in early breast cancer and its correlation with circulating tumor cells].
Breast Neoplasms
[The expression of MMPs and TIMPs in human breast cancer tissues and importance of their balance in cancer invasion and metastasis]
Breast Neoplasms
[Zymography--method for quantitation of activity on gelatinase A (pro-MMP-2, 72 kDa) and gelatinase B (pro-MMP-9, 92 kDa) in serum of patients with breast cancer]
Bronchial Hyperreactivity
Tachykinins induce gelatinase production by guinea pig alveolar macrophages: involvement of NK2 receptors.
Bronchiectasis
Matrix metalloproteinase activation by free neutrophil elastase contributes to bronchiectasis progression in early cystic fibrosis.
Bronchiectasis
Matrix Metalloproteinases Vary with Airway Microbiota Composition and Lung Function in Non-Cystic Fibrosis Bronchiectasis.
Bronchiectasis
Soluble membrane-type 1 matrix metalloproteinase (MT1-MMP) and gelatinase A (MMP-2) in induced sputum and bronchoalveolar lavage fluid of human bronchial asthma and bronchiectasis.
Bronchiolitis
Regression of Allograft Airway Fibrosis The Role of MMP-Dependent Tissue Remodeling in Obliterative Bronchiolitis after Lung Transplantation.
Bronchiolitis Obliterans
Increased net gelatinase but not serine protease activity in bronchiolitis obliterans syndrome.
Bronchopulmonary Dysplasia
Gelatinase activities in the airways of premature infants and development of bronchopulmonary dysplasia.
Bronchopulmonary Dysplasia
Low levels of tissue inhibitor of metalloproteinase-2 at birth may be associated with subsequent development of bronchopulmonary dysplasia in preterm infants.
Bronchopulmonary Dysplasia
MMP-2 and MMP-9 and their tissue inhibitors in the plasma of preterm and term neonates.
Bundle-Branch Block
Polymorphisms of MMP-2 gene are associated with systolic heart failure prognosis.
Burkitt Lymphoma
PEG10 promotes the migration of human Burkitt's lymphoma cells by up-regulating the expression of matrix metalloproteinase-2 and -9.
Burning Mouth Syndrome
Effect of a Homemade Salivary Substitute Prepared Using Chamomile (Matricaria chamomilla L.) Flower and Flax (Linum usitatissimum L.) Seed to Relieve Primary Burning Mouth Syndrome: A Preliminary Report.
Campylobacter Infections
Colonic Expression of Genes Encoding Inflammatory Mediators and Gelatinases During Campylobacter Jejuni Infection of Conventional Infant Mice.
Campylobacter Infections
Selective gelatinase inhibition reduces apoptosis and pro-inflammatory immune cell responses in Campylobacter jejuni-infected gnotobiotic IL-10 deficient mice.
Capsule Opacification
Induction of matrix metalloproteinases 2 and 9 following stress to the lens.
Carcinogenesis
A significant elevation of plasma level of matrix metalloproteinase-9 in patients with high-grade intraepithelial neoplasia and early squamous cell carcinoma of the uterine cervix.
Carcinogenesis
A study on angiogenesis-related matrix metalloproteinase networks in primary hepatocellular carcinoma.
Carcinogenesis
Active matrix metalloproteinase-2 activity discriminates colonic mucosa, adenomas with and without high-grade dysplasia, and cancers.
Carcinogenesis
Angiogenin contributes to bladder cancer tumorigenesis by DNMT3b-mediated MMP2 activation.
Carcinogenesis
Associations between single nucleotide polymorphisms of COX-2 and MMP-2 genes and colorectal cancer susceptibility in the Saudi population.
Carcinogenesis
circ-CSPP1 promotes proliferation, invasion and migration of ovarian cancer cells by acting as a miR-1236-3p sponge.
Carcinogenesis
CKAP2 Promotes Ovarian Cancer Proliferation and Tumorigenesis Through the FAK-ERK Pathway.
Carcinogenesis
Cutaneous carcinomas and preinvasive neoplastic lesions. Role of MMP-2 and MMP-9 metalloproteinases in neoplastic invasion and their relationship with proliferative activity and p53 expression.
Carcinogenesis
Effect of epithelial growth factor on matrix metalloproteinase-2 and E-cadherin/?-catenin expression in an in situ model of tumorigenesis.
Carcinogenesis
Effects of oral contraceptives or a gonadotropin-releasing hormone agonist on ovarian carcinogenesis in genetically engineered mice.
Carcinogenesis
Evaluation of matrix metalloproteinase 2 expression in cervical carcinogenesis using tissue array and integrated optical density for immunoreactivity.
Carcinogenesis
Expression analysis of three miRNAs, miR-26a, miR-29b and miR-519d, in relation to MMP-2 expression level in non-small cell lung cancer patients: a pilot study.
Carcinogenesis
Expression and localization of matrix-degrading metalloproteinases during colorectal tumorigenesis.
Carcinogenesis
Expression of matrix metalloproteinase 2 (MMP-2), membrane-type 1 MMP and tissue inhibitor of metalloproteinase 2 and activation of proMMP-2 in pancreatic duct adenocarcinomas in hamsters treated with N-nitrosobis(2-oxopropyl)amine.
Carcinogenesis
Expression of Matrix Metalloproteinase-2, but not Caspase-3, Facilitates Distinction between Benign and Malignant Thyroid Follicular Neoplasms.
Carcinogenesis
Expression of peroxisome proliferator-activated receptor g, E-cadherin and matrix metalloproteinases-2 in gastric carcinoma and lymph node metastases.
Carcinogenesis
Functional genotype in matrix metalloproteinases-2 promoter is a risk factor for oral carcinogenesis.
Carcinogenesis
Gelatinases A and B expression in human colorectal cancer in upper Egypt: a clinicopathological study.
Carcinogenesis
High expression of tissue inhibitor of metalloproteinase-2 in serous ovarian carcinomas and the role of this expression in ovarian tumorigenesis.
Carcinogenesis
In vivo optical imaging of MMP2 immuno protein antibody: tumor uptake is associated with MMP2 activity.
Carcinogenesis
Increased expression of matrix metalloproteinase-2 and 9 and human papilloma virus infection are associated with malignant transformation of sinonasal inverted papilloma.
Carcinogenesis
Increased expression of MMP-2 and MMP-9 in esophageal squamous cell carcinoma.
Carcinogenesis
Inflammatory and tumorigenic effects of environmental pollutants found in particulate matter on lung epithelial cells.
Carcinogenesis
Loss of basement membrane type IV collagen is associated with increased expression of metalloproteinases 2 and 9 (MMP-2 and MMP-9) during human colorectal tumorigenesis.
Carcinogenesis
Matrix metalloproteinase inhibitors: do they have a place in anticancer therapy?
Carcinogenesis
Matrix metalloproteinase-2 (MMP-2) and its tissue inhibitor (TIMP-2) are prognostic factors in cervical cancer, related to invasive disease but not to high-risk human papillomavirus (HPV) or virus persistence after treatment of CIN.
Carcinogenesis
Matrix metalloproteinase-2 expression in laryngeal preneoplastic and neoplastic lesions.
Carcinogenesis
MMP-2 mRNA Expression in Ovarian Cancer Tissues Predicts Patients' Response to Platinum-Taxane Chemotherapy.
Carcinogenesis
MMP-9 directed shRNAs as relevant inhibitors of matrix metalloproteinase 9 activity and signaling.
Carcinogenesis
Modulating Effect of Enicostemma littorale on the Expression Pattern of Apoptotic, Cell Proliferative, Inflammatory and Angiogenic Markers During 7, 12-Dimethylbenz (a) Anthracene Induced Hamster Buccal Pouch Carcinogenesis.
Carcinogenesis
Modulatory effect of hesperidin on benzo(a)pyrene induced experimental lung carcinogenesis with reference to COX-2, MMP-2 and MMP-9.
Carcinogenesis
Molecular biology of the nasal airways: how do we assess cellular and molecular responses in the nose?
Carcinogenesis
Neutral endopeptidase 24.11/CD10 suppresses progressive potential in ovarian carcinoma in vitro and in vivo.
Carcinogenesis
Olive Leaf Extract and Its Main Component Oleuropein Prevent Chronic Ultraviolet B Radiation-Induced Skin Damage and Carcinogenesis in Hairless Mice.
Carcinogenesis
Oncogenic roles of astrocyte elevated gene-1 (AEG-1) in osteosarcoma progression and prognosis.
Carcinogenesis
Oncogenic transformation of human benign prostate hyperplasia with chronic cadmium exposure.
Carcinogenesis
Overexpression of 5-lipoxygenase and its relation with cell proliferation and angiogenesis in 7,12-dimethylbenz(?)anthracene-induced rat mammary carcinogenesis.
Carcinogenesis
Overexpression of EMMPRIN Isoform 2 Is Associated with Head and Neck Cancer Metastasis.
Carcinogenesis
POU5F1 enhances the invasiveness of cancer stem-like cells in lung adenocarcinoma by upregulation of MMP-2 expression.
Carcinogenesis
Resveratrol Inhibits the Epithelial-Mesenchymal Transition of Pancreatic Cancer Cells Via Suppression of the PI-3K/Akt/NF-?B Pathway.
Carcinogenesis
Rho Guanine Nucleotide Exchange Factor 5 Increases Lung Cancer Cell Tumorigenesis via MMP-2 and Cyclin D1 Upregulation.
Carcinogenesis
Role of the TNF-? receptor type 1 on prostate carcinogenesis in knockout mice.
Carcinogenesis
Semi-quantitative expression of tissue inhibitor of matrix metalloproteinase-2 in cancer of uterine cervix.
Carcinogenesis
Silymarin attenuated mast cell recruitment thereby decreased the expressions of matrix metalloproteinases-2 and 9 in rat liver carcinogenesis.
Carcinogenesis
The anti-invasive role of novel synthesized pyridazine hydrazide appended phenoxy acetic acid against neoplastic development targeting matrix metallo proteases.
Carcinogenesis
The Anti-tumoral Effect of ?-D-Mannuronic Acid (M2000) as a Novel NSAID on Treg Cells Frequency and MMP-2, MMP-9, CCL22 and TGF?1 Gene Expression in Pre-surgical Breast Cancer Patients.
Carcinogenesis
The inhibition of MAPK pathway is correlated with down-regulation of MMP-9 secretion induced by TNF-alpha in human keratinocytes.
Carcinogenesis
The interaction between aromatase, metalloproteinase 2,9 and cd44 in breast cancer.
Carcinogenesis
The protective role of the -1306C>T functional polymorphism in matrix metalloproteinase-2 gene is associated with cervical cancer: implication of human papillomavirus infection.
Carcinogenesis
The role of matrix metalloproteinases 2 and 9 during rat tongue carcinogenesis induced by 4-nitroquinoline 1-oxide.
Carcinogenesis
Transcriptional expression of the genes implicated in angiogenesis and tumor invasion in cervical carcinomas.
Carcinogenesis
Trichostatin A-histone deacetylase inhibitor with clinical therapeutic potential-is also a selective and potent inhibitor of gelatinase A expression.
Carcinogenesis
[Clinicopathological significance of expressions of RECK and MMP-2 in esophageal squamous carcinoma]
Carcinogenesis
[Dynamic study on expression of gelatinase A and its natural inhibitor during invasion and metastasis of induced lung cancer in Wistar rats]
Carcinogenesis
[Expression and clinical significance of matrix metalloproteinase-2 in laryngeal squamous cell carcinoma]
Carcinogenesis
[Expression of MMP-2 and its clinical significance in cervical squamous carcinoma]
Carcinogenesis
[Expression of MMP-2, HIF-1alpha and VEGF in Colon Adenoma and Colon Cancer.]
Carcinogenesis
[Gelatinases A and B and their endogenous regulators in the corpus uteri in squamous cell cervical carcinoma].
Carcinogenesis
[Molecular mechanism of reversing metastatic phenotype in human high-metastatic large cell lung cancer cell line L9981 by nm23-H1]
Carcinogenesis
[State of the liver antioxidant system and content of matrix metalloproteinase-2 of the large intestine under the effect of maleimide derivative in experimental colorectal carcinogenesis in rats].
Carcinogenesis
[The matrix metalloproteinase in oral and oropharyngeol cancer - literature review].
Carcinogenesis
[The role of matrix metalloproteinases and their tissue inhibitors in oral lichen planus]
Carcinoid Tumor
Correlation of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinase expression in ileal carcinoids, lymph nodes and liver metastasis with prognosis and survival.
Carcinoid Tumor
Expression of gelatinase A, tissue inhibitor of metalloproteinases-2, matrilysin, and trypsin(ogen) in lung neoplasms: an immunohistochemical study.
Carcinoid Tumor
GHRH antagonist inhibits focal adhesion kinase (FAK) and decreases expression of vascular endothelial growth factor (VEGF) in human lung cancer cells in vitro.
Carcinoma
72 KD and 92 KD type IV collagenase, type IV collagen, and laminin mRNAs in breast cancer: a study by in situ hybridization.
Carcinoma
72-kD (MMP-2) and 92-kD (MMP-9) type IV collagenase production and activity in different histologic types of lung cancer cells.
Carcinoma
92-kd gelatinase is actively expressed by eosinophils and stored by neutrophils in squamous cell carcinoma.
Carcinoma
A multicenter study on expressions of vascular endothelial growth factor, matrix metallopeptidase-9 and tissue inhibitor of metalloproteinase-2 in oral and maxillofacial squamous cell carcinoma.
Carcinoma
A role for focal adhesion kinase in hyluronan-dependent MMP-2 secretion in a human small-cell lung carcinoma cell line, QG90.
Carcinoma
Aberrant activation of Wnt/?-catenin signaling pathway contributes to the sequential progression of DMBA-induced HBP carcinomas.
Carcinoma
Activated matrix metalloproteinase-2--a potential marker of prognosis for epithelial ovarian cancer.
Carcinoma
Activation of matrix metalloproteinase-2 in head and neck squamous cell carcinoma: studies of clinical samples and in vitro cell lines co-cultured with fibroblasts.
Carcinoma
Activation of pro-MMP-2 mediated by MT1-MMP in human salivary gland carcinomas: possible regulation of pro-MMP-2 activation by TIMP-2.
Carcinoma
Activation of the precursor of gelatinase A/72 kDa type IV collagenase/MMP-2 in lung carcinomas correlates with the expression of membrane-type matrix metalloproteinase (MT-MMP) and with lymph node metastasis.
Carcinoma
Activation of Toll-Like Receptor-9 Promotes Cellular Migration via Up-Regulating MMP-2 Expression in Oral Squamous Cell Carcinoma.
Carcinoma
Active matrix metalloproteinase-2 activity discriminates colonic mucosa, adenomas with and without high-grade dysplasia, and cancers.
Carcinoma
Activity and cellular origin of gelatinases in patients with colon and rectal carcinoma differential activity of matrix metalloproteinase-9.
Carcinoma
Activity of type IV collagenases (MMP-2 and MMP-9) in primary pulmonary carcinomas: a quantitative analysis.
Carcinoma
ADAM17 is associated with EMMPRIN and predicts poor prognosis in patients with uterine cervical carcinoma.
Carcinoma
Adenovirus-mediated ING4 expression suppresses lung carcinoma cell growth via induction of cell cycle alteration and apoptosis and inhibition of tumor invasion and angiogenesis.
Carcinoma
AG-9, an Elastin-Derived Peptide, Increases In Vitro Oral Tongue Carcinoma Cell Invasion, through an Increase in MMP-2 Secretion and MT1-MMP Expression, in a RPSA-Dependent Manner.
Carcinoma
ALDH1A1 defines invasive cancer stem-like cells and predicts poor prognosis in patients with esophageal squamous cell carcinoma.
Carcinoma
Alteration of MMP-2 and -14 expression by imatinib in HPV-positive and -negative squamous cell carcinoma.
Carcinoma
Alterations in enhancer of zeste homolog 2, matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 expression are associated with ex vivo and in vitro bone metastasis in renal cell carcinoma.
Carcinoma
Altered expression of metastasis-associated and regulatory molecules in effusions from breast cancer patients: a novel model for tumor progression.
Carcinoma
Ameloblastic neoplasia spectrum: a cross-sectional study of MMPS expression and proliferative activity.
Carcinoma
Analysis of expression of matrix metalloproteinases-2 and -9 in hypopharyngeal squamous cell carcinoma by in situ hybridization.
Carcinoma
Anti-cancer Effect of 20(S)-Ginsenoside-Rh2 on Oral Squamous Cell Carcinoma Cells via the Decrease in ROS and Downregulation of MMP-2 and VEGF.
Carcinoma
Anti-invasive effect of MMI-166, a new selective matrix metalloproteinase inhibitor, in cervical carcinoma cell lines.
Carcinoma
Anti-proliferative and matrix metalloproteinase-2 inhibition of Longkong (Lansium domesticum) extracts on human mouth epidermal carcinoma.
Carcinoma
Anticancer effect of lysine, proline, arginine, ascorbic acid and green tea extract on human renal adenocarcinoma line 786-0.
Carcinoma
Antimetastatic Effects of Sesamin on Human Head and Neck Squamous Cell Carcinoma through Regulation of Matrix Metalloproteinase-2.
Carcinoma
Antimetastatic potentials of salvianolic acid A on oral squamous cell carcinoma by targeting MMP-2 and the c-Raf/MEK/ERK pathway.
Carcinoma
Association between expression of activated 72-kilodalton gelatinase and tumor spread in non-small-cell lung carcinoma.
Carcinoma
Associations of Promoter Methylations and mRNA Expressions of MMP-2, MMP-7 and MMP-9 with Primary Fallopian Tube Carcinoma.
Carcinoma
Augmented membrane type 1 matrix metalloproteinase (MT1-MMP):MMP-2 messenger RNA ratio in gastric carcinomas with poor prognosis.
Carcinoma
Aurora-A modulates MMP-2 expression via AKT/NF-?B pathway in esophageal squamous cell carcinoma cells.
Carcinoma
Autocrine factor enhancing the secretion of M(r) 95,000 gelatinase (matrix metalloproteinase 9) in serum-free medium conditioned with murine metastatic colon carcinoma cells.
Carcinoma
BAG3 (BCL2-associated athanogene 3) interacts with MMP-2 to positively regulate invasion by ovarian carcinoma cells.
Carcinoma
Basement membrane collagen-degrading activity from a malignant tumor is inhibited by anthracycline antibiotics.
Carcinoma
Behavior of the basement membrane during carcinoma cell invasion in chemically induced carcinomas of the skin.
Carcinoma
Behaviour of basement membrane antigens in gastric and colorectal cancer. Immunohistochemical study.
Carcinoma
Blockage of Squamous Cancer Cell Collective Invasion by FAK Inhibition Is Released by CAFs and MMP-2.
Carcinoma
Caffeoyl pyrrolidine derivative LY52 inhibits tumor invasion and metastasis via suppression of matrix metalloproteinase activity.
Carcinoma
Cancer-Specific Survival Stratification Derived from Tumor Expression of Tissue Inhibitor of Metalloproteinase-2 in Non-Metastatic Renal Cell Carcinoma.
Carcinoma
Cancer/Testis Antigens: Expression, Regulation, Tumor Invasion, and Use in Immunotherapy of Cancers.
Carcinoma
CD147 and matrix metalloproteinase-2 protein expression as significant prognostic factors in esophageal squamous cell carcinoma.
Carcinoma
CD40L induces matrix-metalloproteinase-9 but not tissue inhibitor of metalloproteinases-1 in cervical carcinoma cells: imbalance between NF-kappaB and STAT3 activation.
Carcinoma
Cellular protein and mRNA expression patterns of matrix metalloproteinases-2, -3 and -9 in human breast cancer: correlation with tumour growth.
Carcinoma
Characterization of gelatinases linked to extracellular matrix invasion in ovarian adenocarcinoma: purification of matrix metalloproteinase 2.
Carcinoma
Chronic stress promotes oral cancer growth and angiogenesis with increased circulating catecholamine and glucocorticoid levels in a mouse model.
Carcinoma
Clinical significance of expression of membrane type 1 matrix metalloproteinase and matrix metalloproteinase-2 in human head and neck squamous cell carcinoma.
Carcinoma
Clinical significance of secreted protein acidic and rich in cystein in esophageal carcinoma and its relation to carcinoma progression.
Carcinoma
Clinicopathologic and prognostic significance of matrix metalloproteinases in rectal cancer.
Carcinoma
Clinicopathological significance of matrix metalloproteinase 2 protein expression in patients with renal cell carcinoma: A case-control study and meta-analysis.
Carcinoma
Clinicopathological Significance of Matrix Metalloproteinase-2 Protein Expression in Renal Cell Carcinoma Patients.
Carcinoma
Collagenase-3 expression is associated with advanced local invasion in human squamous cell carcinomas of the larynx.
Carcinoma
Combination therapy including a gelatinase inhibitor and cytotoxic agent reduces local invasion and metastasis of murine Lewis lung carcinoma.
Carcinoma
Comparative Analysis of P63, Maspin and Matrix Metalloproteinase 2 Expression in Mucoepidermoid Carcinoma and Adenoid Cystic Carcinoma of Salivary Glands.
Carcinoma
Comparative analysis of the expression of metalloproteases (MMP-2, MMP-9, MMP-11 and MMP-13) and the tissue inhibitor of metalloprotease 3 (TIMP-3) between previous negative biopsies and radical prostatectomies.
Carcinoma
Comparative expression of matrix metalloproteinases in low-grade mucoepidermoid carcinoma and typical lung cancer.
Carcinoma
Comparative study of MMP-2 (matrix metalloproteinase 2) immune expression in normal uterine cervix, intraepithelial neoplasias, and squamous cells cervical carcinoma.
Carcinoma
Comparison of matrix metalloproteinase expression between primary tumors with or without liver metastasis in pancreatic and colorectal carcinomas.
Carcinoma
Comparisons of efficacy and safety between docetaxel + cisplatin and paclitaxel + cisplatin and their effects on serum HE4, CA125 and ROMA indicators in patients with ovarian carcinoma.
Carcinoma
Concomitant reduction of matrix metalloproteinase-2 secretion and intracellular reactive oxygen species following anti-sense inhibition of telomerase activity in PC-3 prostate carcinoma cells.
Carcinoma
Contribution of the PI3K/MMPs/Ln-5?2 and EphA2/FAK/Paxillin signaling pathways to tumor growth and vasculogenic mimicry of gallbladder carcinomas.
Carcinoma
Coordinated expression of integrin subunits, matrix metalloproteinases (MMP), angiogenic genes and Ets transcription factors in advanced-stage ovarian carcinoma: a possible activation pathway?
Carcinoma
Correction: liang, j., et Al. Antisense oligonucleotide against clusterin regulates human hepatocellular carcinoma invasion through transcriptional regulation of matrix metalloproteinase-2 and e-cadherin. Int. J. Mol. Sci. 2012, 13, 10594-10607.
Carcinoma
Correlation and prognostic significance of MMP-2 and TFPI-2 differential expression in pancreatic carcinoma.
Carcinoma
Correlation between vascular endothelial growth factor-C expression and invasion phenotype in cervical carcinomas.
Carcinoma
Correlation of matrix metalloproteinase-2, -9, tissue inhibitor-1 of matrix metalloproteinase and CD44 variant 6 in head and neck cancer metastasis.
Carcinoma
Correlation of the in situ detection of polymerase chain reaction-amplified metalloproteinase complementary DNAs and their inhibitors with prognosis in cervical carcinoma.
Carcinoma
Correspondence re: C. F. M. Sier et al., Enhanced urinary gelatinase activities (matrix metalloproteinases 2 and 9) are associated with early-stage bladder carcinoma: a comparison with clinically used tumor markers. Clin. Cancer Res., 6: 2333-2340, 2000.
Carcinoma
Corrigendum: HCRP-1 regulates cell migration and invasion via EGFR-ERK mediated up-regulation of MMP-2 with prognostic significance in human renal cell carcinoma.
Carcinoma
Critical roles of Wnt5a-Ror2 signaling in aggressiveness of tongue squamous cell carcinoma and production of matrix metalloproteinase-2 via ?Np63?-mediated epithelial-mesenchymal transition.
Carcinoma
Curcumin Inhibits Invasiveness and Epithelial-Mesenchymal Transition in Oral Squamous Cell Carcinoma Through Reducing Matrix Metalloproteinase 2, 9 and Modulating p53-E-Cadherin Pathway.
Carcinoma
Cutaneous carcinomas and preinvasive neoplastic lesions. Role of MMP-2 and MMP-9 metalloproteinases in neoplastic invasion and their relationship with proliferative activity and p53 expression.
Carcinoma
Cytokine regulation of gelatinase production by head and neck squamous cell carcinoma: the role of tumor necrosis factor-alpha.
Carcinoma
Dehydroandrographolide inhibits oral cancer cell migration and invasion through NF-?B-, AP-1-, and SP-1-modulated matrix metalloproteinase-2 inhibition.
Carcinoma
Design and characterization of a metalloproteinase inhibitor-tethered resin for the detection of active MMPs in biological samples.
Carcinoma
Desmoplastic basal cell carcinomas possess unique basement membrane-degrading properties.
Carcinoma
Desmoplastic response in scirrhous gastric carcinoma: imbalance between collagen synthesis and degradation.
Carcinoma
Detection of differentially expressed gelatinase A in metastatic and non-metastatic subpopulations of tumor cells by target RNA arbitrarily primed polymerase chain reaction (TRAP-PCR).
Carcinoma
Differential expression and activity status of MMP-1, MMP-2 and MMP-9 in tumor and stromal cells of squamous cell carcinomas of the lung.
Carcinoma
Differential expression of E-cadherin and type IV collagenase genes predicts outcome in patients with stage I non-small cell lung carcinoma.
Carcinoma
Differential expression of matrix metalloproteinase (MMP)-2, MMP-9 and tissue inhibitor of metalloproteinase (TIMP)-1 and TIMP-2 in non-melanoma skin cancer: implications for tumour progression.
Carcinoma
Differential expression of matrix metalloproteinase-2 by fibroblasts in co-cultures with keratinocytes, basal cell carcinoma and melanoma.
Carcinoma
Differential expression of MMP and uPA systems and prognostic relevance of their expression in esophageal squamous cell carcinoma.
Carcinoma
Differential regulation of membrane type 1-matrix metalloproteinase activity by ERK 1/2- and p38 MAPK-modulated tissue inhibitor of metalloproteinases 2 expression controls transforming growth factor-beta1-induced pericellular collagenolysis.
Carcinoma
DJ-1 is involved in the peritoneal metastasis of gastric cancer through activation of the Akt signaling pathway.
Carcinoma
Down-regulation of E-cadherin in mouse skin carcinoma cells enhances a migratory and invasive phenotype linked to matrix metalloproteinase-9 gelatinase expression.
Carcinoma
Downregulation of G3BPs inhibits the growth, migration and invasion of human lung carcinoma H1299 cells by suppressing the Src/FAK-associated signaling pathway.
Carcinoma
Downregulation of miR-21 regulates MMP-2 expression and suppress migration of Laryngeal squamous cell carcinoma.
Carcinoma
Dual regulation of MMP-2 expression by the type 1 insulin-like growth factor receptor: the phosphatidylinositol 3-kinase/Akt and Raf/ERK pathways transmit opposing signals.
Carcinoma
E1AF expression is closely correlated with malignant phenotype of tongue squamous cell carcinoma through activation of MT1-MMP gene promoters.
Carcinoma
Early acquisition of gelatinolytic activity in carcinogenesis of the uterine cervix.
Carcinoma
Effect of DAPK1 gene on proliferation, migration, and invasion of carcinoma of pancreas BxPC-3 cell line.
Carcinoma
Effect of epithelial growth factor on matrix metalloproteinase-2 and E-cadherin/?-catenin expression in an in situ model of tumorigenesis.
Carcinoma
Effect on the Expression of MMP-2, MT-MMP in Laryngeal Carcinoma Hep-2 Cell Line by Antisense Glucose Transporter-1.
Carcinoma
Effects of a KiSS-1 peptide, a metastasis suppressor gene, on the invasive ability of renal cell carcinoma cells through a modulation of a matrix metalloproteinase 2 expression.
Carcinoma
Effects of basic fibroblast factor (bFGF) on MMP-2, TIMP-2, and type-I collagen levels in human lung carcinoma fibroblasts.
Carcinoma
Effects of matrix metalloproteinase inhibitor doxycycline and CD147 antagonist peptide-9 on gallbladder carcinoma cell lines.
Carcinoma
Effects of RNA silencing of matrix metalloproteinase-2 on the growth of esophageal carcinoma cells in vivo.
Carcinoma
Effects of RNAi-mediated matrix metalloproteinase-2 gene silencing on the invasiveness and adhesion of esophageal carcinoma cells, KYSE150.
Carcinoma
Elevation of serum levels of matrix metalloproteinase-2 and -3 as new predictors of recurrence in patients with urothelial carcinoma.
Carcinoma
EMMPRIN-induced MMP-2 activation cascade in human cervical squamous cell carcinoma.
Carcinoma
Enhanced cell surface expression of matrix metalloproteinases and their inhibitors, and tumor-induced host response in progression of human gastric carcinoma.
Carcinoma
Enhanced production and activation of progelatinase A mediated by membrane-type 1 matrix metalloproteinase in human oral squamous cell carcinomas: implications for lymph node metastasis.
Carcinoma
Enhanced production and activation of progelatinase A mediated by membrane-type 1 matrix metalloproteinase in human papillary thyroid carcinomas.
Carcinoma
Enhanced production of matrix metalloproteinase-2 in human head and neck carcinomas is correlated with lymph node metastasis.
Carcinoma
Enhanced production of matrix metalloproteinases and activation of matrix metalloproteinase 2 (gelatinase A) in human gastric carcinomas.
Carcinoma
Enhanced urinary gelatinase activities (matrix metalloproteinases 2 and 9) are associated with early-stage bladder carcinoma: a comparison with clinically used tumor markers.
Carcinoma
Epigallocatechin gallate sensitizes CAL-27 human oral squamous cell carcinoma cells to the anti-metastatic effects of gefitinib (Iressa) via synergistic suppression of epidermal growth factor receptor and matrix metalloproteinase-2.
Carcinoma
Epithelial expression of extracellular matrix metalloproteinase inducer/CD147 and matrix metalloproteinase-2 in neoplasms and precursor lesions derived from cutaneous squamous cells: An immunohistochemical study.
Carcinoma
Epithelial-mesenchymal transition in oral squamous cell carcinoma triggered by transforming growth factor-beta1 is Snail family-dependent and correlates with matrix metalloproteinase-2 and -9 expressions.
Carcinoma
Evaluation of basement membrane components and the 72 kDa type IV collagenase in serous tumors of the ovary.
Carcinoma
Evaluation of matrix metalloproteinase 2 expression in cervical carcinogenesis using tissue array and integrated optical density for immunoreactivity.
Carcinoma
Expression and clinical significance of matrix metalloproteinase-2 and matrix metalloproteinase-9 in oral squamous cell carcinoma.
Carcinoma
Expression and correlation of CD44v6, vascular endothelial growth factor, matrix metalloproteinase-2, and matrix metalloproteinase-9 in Krukenberg tumor.
Carcinoma
Expression and localization of matrix-degrading metalloproteinases during colorectal tumorigenesis.
Carcinoma
Expression and role of matrix metalloproteinases MMP-2 and MMP-9 in human spinal column tumors.
Carcinoma
Expression and tissue localization of membrane-types 1, 2, and 3 matrix metalloproteinases in human invasive breast carcinomas.
Carcinoma
Expression of 92-kDa type IV collagenase mRNA by eosinophils associated with basal cell carcinoma.
Carcinoma
Expression of C-X-C chemokine receptor types 1/2 in patients with gastric carcinoma: Clinicopathological correlations and significance.
Carcinoma
Expression of cyclooxygenase-2 in renal cell carcinoma: correlation with tumor cell proliferation, apoptosis, angiogenesis, expression of matrix metalloproteinase-2, and survival.
Carcinoma
Expression of cyclooxygenase-2, vascular endothelial growth factor and matrix metalloproteinase-2 in patients with primary laryngeal carcinoma: a tissue microarray study.
Carcinoma
Expression of FLJ10540 is correlated with aggressiveness of oral cavity squamous cell carcinoma by stimulating cell migration and invasion through increased FOXM1 and MMP-2 activity.
Carcinoma
Expression of gelatinase A and TIMP-2 mRNAs in desmoplastic fibroblasts in both mammary carcinomas and basal cell carcinomas of the skin.
Carcinoma
Expression of gelatinase A, tissue inhibitor of metalloproteinases-2, matrilysin, and trypsin(ogen) in lung neoplasms: an immunohistochemical study.
Carcinoma
Expression of Gelatinases (MMP-2, MMP-9) and Gelatinase Activator (MMP-14) in Actinic Keratosis and in In Situ and Invasive Squamous Cell Carcinoma.
Carcinoma
Expression of integrin alphaVbeta3 in pancreatic carcinoma: relation to MMP-2 activation and lymph node metastasis.
Carcinoma
Expression of laminin, collagen IV, fibronectin, and type IV collagenase in gastric carcinoma. An immunohistochemical study of 87 patients.
Carcinoma
Expression of matrix metalloprotease-2 (MMP-2) and the activator membrane type 1 (MT1-MMP) in canine mammary carcinomas.
Carcinoma
Expression of matrix metalloproteinase (MMP)-2 and MMP-9 in breast cancer with a special reference to activator protein-2, HER2, and prognosis.
Carcinoma
Expression of matrix metalloproteinase 1, matrix metalloproteinase 2, and matrix metalloproteinase 9 in carcinoma of the head and neck.
Carcinoma
Expression of matrix metalloproteinase 2 (MMP-2), E-cadherin and Ki-67 in metastatic and non-metastatic canine mammary carcinomas.
Carcinoma
Expression of matrix metalloproteinase 2 (MMP-2), membrane-type 1 MMP and tissue inhibitor of metalloproteinase 2 and activation of proMMP-2 in pancreatic duct adenocarcinomas in hamsters treated with N-nitrosobis(2-oxopropyl)amine.
Carcinoma
Expression of matrix metalloproteinase 2 and its tissue inhibitor in oral squamous cell carcinoma.
Carcinoma
Expression of matrix metalloproteinase-1, -2 and -3 in squamous cell carcinoma and actinic keratosis.
Carcinoma
Expression of matrix metalloproteinase-2 (MMP-2) and of membrane-type-1-matrix metalloproteinase (MT1-MMP) in transitional cell carcinoma of the upper urinary tract.
Carcinoma
Expression of matrix metalloproteinase-2 (mmp-2) in cervical neoplasia - immunohistochemical and in-situ hybridization studies.
Carcinoma
Expression of matrix metalloproteinase-2 and -9 in oral squamous cell carcinomas with regard to the metastatic potential.
Carcinoma
Expression of matrix metalloproteinase-2 and 9 in cervical intraepithelial neoplasia and cervical carcinoma among different age groups of premenopausal and postmenopausal women.
Carcinoma
Expression of matrix metalloproteinase-2 in preinvasive and invasive carcinoma of the uterine cervix.
Carcinoma
Expression of matrix metalloproteinase-2 related to lymph node metastasis of oral squamous cell carcinoma. A clinicopathologic study.
Carcinoma
Expression of matrix metalloproteinases (MMP-1 and -2) and their inhibitors (TIMP-1, -2 and -3) in oral lichen planus, dysplasia, squamous cell carcinoma and lymph node metastasis.
Carcinoma
Expression of matrix metalloproteinases (MMP-2 and MMP-9) in recurrent respiratory papillomas and laryngeal carcinoma: clinical and morphological parallels.
Carcinoma
Expression of matrix metalloproteinases (MMP-2, MMP-9, MT1-MMP) and their inhibitors (TIMP-1, TIMP-2) in common epithelial tumors of the ovary.
Carcinoma
Expression of matrix metalloproteinases (MMPs-2, -7, -9, and -26) and tissue inhibitors of metalloproteinases (TIMPs-1 and -2) in pleomorphic adenomas and adenoid cystic carcinomas.
Carcinoma
Expression of Matrix Metalloproteinases and Its Inhibitor in Gastric Adenocarcinoma.
Carcinoma
Expression of matrix metalloproteinases and related tissue inhibitors in the cyst fluids of ovarian mucinous neoplasms.
Carcinoma
Expression of matrix metalloproteinases and tissue inhibitor of matrix metalloproteinases in non-small-cell lung cancer.
Carcinoma
Expression of matrix metalloproteinases and tissue inhibitor of metalloproteinases in head and neck squamous cell carcinoma.
Carcinoma
Expression of matrix metalloproteinases in benign and malignant follicular thyroid lesions.
Carcinoma
Expression of matrix metalloproteinases in gallbladder carcinoma and their significance in carcinogenesis.
Carcinoma
Expression of matrix metalloproteinases in supraglottic carcinoma and its clinical implication for estimating lymph node metastases.
Carcinoma
Expression of matrix metalloproteinases MMP-2, MMP-9 and their tissue inhibitors TIMP-1, -2, and -3 in benign and malignant tumours of the salivary gland.
Carcinoma
Expression of matrix metalloproteinases-2 and -9 by cells isolated from the peritoneal fluid of women with ovarian carcinoma.
Carcinoma
Expression of membrane type 1 matrix metalloproteinase (MMP-14) in epithelial ovarian cancer: high level expression in clear cell carcinoma.
Carcinoma
Expression of membrane type 1 matrix metalloproteinase, matrix metalloproteinase 2 and tissue inhibitor of metalloproteinase 2 in human cartilaginous tumors with special emphasis on mesenchymal and dedifferentiated chondrosarcoma.
Carcinoma
Expression of membrane-type-1-matrix metalloproteinase and metalloproteinase-2 in nonsmall cell lung carcinomas.
Carcinoma
Expression of metalloproteinase 2 and 9 and their inhibitors in renal cell carcinoma.
Carcinoma
Expression of metalloproteinase-2, metalloproteinase-9, and tissue inhibitor of metalloproteinase-1 in transitional cell carcinoma of upper urinary tract: correlation with tumor stage and survival.
Carcinoma
Expression of MMP-2 and MMP-9, their inhibitors, and the activator MT1-MMP in primary breast carcinomas.
Carcinoma
Expression of MMP-2 correlates with increased angiogenesis in CNS metastasis of lung carcinoma.
Carcinoma
Expression of MMP-2 is associated with progression and lymph node metastasis of gastric carcinoma.
Carcinoma
Expression of MMP-2, -9 and -13 in cell lines and fresh biopsies of squamous cell carcinomas of the upper aerodigestive tract.
Carcinoma
Expression of MMP-2,TIMP-2 protein and the ratio of MMP-2/TIMP-2 in gallbladder carcinoma and their significance.
Carcinoma
Expression of mRNA for gelatinase A and TIMP-2 in cell cultures and tissue samples derived from breast and lung carcinomas.
Carcinoma
Expression of nm23, MMP-2, TIMP-2 in breast neoplasm in Zhengzhou Center Hospital, China.
Carcinoma
Expression of nm23-H1 gene product in sarcomatous cancer cells of renal cell carcinoma: correlation with tumor stage and expression of matrix metalloproteinase-2, matrix metalloproteinase-9, sialyl Lewis X, and c-erbB-2.
Carcinoma
Expression of peroxisome proliferator-activated receptor g, E-cadherin and matrix metalloproteinases-2 in gastric carcinoma and lymph node metastases.
Carcinoma
Expression of RECK and MMP-2 in salivary adenoid cystic carcinoma: Correlation with tumor progression and patient prognosis.
Carcinoma
Expression of the metalloproteinase matrilysin in DU-145 cells increases their invasive potential in severe combined immunodeficient mice.
Carcinoma
Expression of tissue inhibitor of matrix metalloproteinase-2 correlates with activation of matrix metalloproteinase-2 and predicts poor prognosis in tongue squamous cell carcinoma.
Carcinoma
Expression of type IV collagen and matrix metalloproteinase-2 (type IV collagenase) in relation to nodal status in laryngeal cancer.
Carcinoma
Expression of type IV collagen, metalloproteinase-2, metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in laryngeal squamous cell carcinomas.
Carcinoma
Expression profile of epithelial-mesenchymal transition markers in non-muscle-invasive urothelial carcinoma of the bladder: correlation with intravesical recurrence following transurethral resection.
Carcinoma
Expressions of CD147, MMP-2 and MMP-9 in Laryngeal Carcinoma and its Correlation with Poor Prognosis.
Carcinoma
Expressions of MMP-2, MMP-9 and VEGF are closely linked to growth, invasion, metastasis and angiogenesis of gastric carcinoma.
Carcinoma
Front-cell-specific expression of membrane-type 1 matrix metalloproteinase and gelatinase A during cohort migration of colon carcinoma cells induced by hepatocyte growth factor/scatter factor.
Carcinoma
Functional genotype in matrix metalloproteinases-2 promoter is a risk factor for oral carcinogenesis.
Carcinoma
Functional haplotypes in the promoter of matrix metalloproteinase-2 predict risk of the occurrence and metastasis of esophageal cancer.
Carcinoma
Galloyl cyclic-imide derivative CH1104I inhibits tumor invasion through suppressing matrix metalloproteinase activity.
Carcinoma
Ganoderic acid T inhibits tumor invasion in vitro and in vivo through inhibition of MMP expression.
Carcinoma
Gelatinase A (MMP-2) and its mRNA detected in both neoplastic and stromal cells of tumors with different invasive and metastatic properties.
Carcinoma
Gelatinase A expression and localization in human breast cancers. An in situ hybridization study and immunohistochemical detection using confocal microscopy.
Carcinoma
Gelatinase A, membrane type 1 matrix metalloproteinase, and extracellular matrix metalloproteinase inducer mRNA expression: correlation with invasive growth of breast cancer.
Carcinoma
Gelatinases and metalloproteinase inhibitor secreted by murine colonic carcinoma cells with differing metastatic potential.
Carcinoma
Gelatinolytic activity of matrix metalloproteinase-2 and -9 in oesophageal carcinoma; a study using in situ zymography.
Carcinoma
Genes of laminin B1 chain, alpha 1 (IV) chain of type IV collagen, and 72-kd type IV collagenase are mainly expressed by the stromal cells of lung carcinomas.
Carcinoma
Granulocyte-macrophage colony-stimulating factor upregulates matrix metalloproteinase-2 (MMP-2) and membrane type-1 MMP (MT1-MMP) in human head and neck cancer cells.
Carcinoma
HCRP-1 regulates cell migration and invasion via EGFR-ERK mediated up-regulation of MMP-2 with prognostic significance in human renal cell carcinoma.
Carcinoma
HIF-1? contributes to hypoxia-induced invasion and metastasis of esophageal carcinoma via inhibiting E-cadherin and promoting MMP-2 expression.
Carcinoma
High expression of tissue inhibitor of metalloproteinase-2 in serous ovarian carcinomas and the role of this expression in ovarian tumorigenesis.
Carcinoma
High levels of MMP-2, MMP-9, MT1-MMP and TIMP-2 mRNA correlate with poor survival in ovarian carcinoma.
Carcinoma
Higher expression and activity of metalloproteinases in human cervical carcinoma cell lines is associated with HPV presence.
Carcinoma
HPV16 oncoproteins induce MMPs/RECK-TIMP-2 imbalance in primary keratinocytes: possible implications in cervical carcinogenesis.
Carcinoma
Human keratinocytes express EMMPRIN, an extracellular matrix metalloproteinase inducer.
Carcinoma
Human MT6-matrix metalloproteinase: identification, progelatinase A activation, and expression in brain tumors.
Carcinoma
Human neutrophil peptide-1 affects matrix metalloproteinase-2, -8 and -9 secretions of oral squamous cell carcinoma cell lines in vitro.
Carcinoma
Human recombinant interferons-beta and -gamma decrease gelatinase production and invasion by human KG-2 renal-carcinoma cells.
Carcinoma
Human tongue carcinoma growth is inhibited by selective antigelatinolytic peptides.
Carcinoma
Hyaluronan-CD44s signaling regulates matrix metalloproteinase-2 secretion in a human lung carcinoma cell line QG90.
Carcinoma
Hypoxia suppresses E-cadherin and enhances matrix metalloproteinase-2 expression favoring esophageal carcinoma migration and invasion via hypoxia inducible factor-1 alpha activation.
Carcinoma
Hypoxia-Induced Cleavage Of Soluble ephrinA1 From Cancer Cells Is Mediated By MMP-2 And Associates With Angiogenesis In Oral Squamous Cell Carcinoma.
Carcinoma
Identification of the 170-kDa melanoma membrane-bound gelatinase (seprase) as a serine integral membrane protease.
Carcinoma
Imatinib-associated matrix metalloproteinase suppression in p16-positive squamous cell carcinoma compared to HPV-negative HNSCC cells in vitro.
Carcinoma
Imbalance between MMP-2, 9 and TIMP-1 promote the invasion and metastasis of renal cell carcinoma via SKP2 signaling pathways.
Carcinoma
Immunocytochemical detection of matrix metalloproteinase expression in prostate cancer.
Carcinoma
Immunoelectron microscopic localization of gelatinase A in human gastrointestinal and skin carcinomas: difference between cancer cells and fibroblasts.
Carcinoma
Immunoexpression of matrix metalloproteinase-2 and matrix metalloproteinase-9 in the metastasis of squamous cell carcinoma of the human tongue.
Carcinoma
Immunoexpression of the PTEN protein and matrix metalloproteinase-2 in endometrial cysts, endometrioid and clear cell ovarian cancer.
Carcinoma
Immunohistochemical evaluation of MMP-2, MMP-9 and CD31/microvascular density in squamous cell carcinomas of the floor of the mouth.
Carcinoma
Immunohistochemical expression of matrix metalloproteinase-1, matrix metalloproteinase-2 and matrix metalloproteinase-9, myofibroblasts and Ki-67 in actinic cheilitis and lip squamous cell carcinoma.
Carcinoma
Immunohistochemical expression of MMP-2 and MMP-8 in oral squamous cell carcinoma.
Carcinoma
Immunohistochemical markers of prolonged survival in small cell carcinoma of the lung. An immunohistochemical study.
Carcinoma
Immunohistochemically detected high expression of matrix metalloproteinase-2 as predictor of poor prognosis in Duke's B colon cancer.
Carcinoma
Immunolocalizations of human gelatinase (type IV collagenase, MMP-9) and TIMP (tissue inhibitor of metalloproteinases) in normal epidermis and some epidermal tumors.
Carcinoma
Implication of collagen type I-induced membrane-type 1-matrix metalloproteinase expression and matrix metalloproteinase-2 activation in the metastatic progression of breast carcinoma.
Carcinoma
In situ detection of PCR-amplified metalloproteinase cDNAs, their inhibitors and human papillomavirus transcripts in cervical carcinoma cell lines.
Carcinoma
In situ mRNA hybridization technique for analysis of metastasis-related genes in human colon carcinoma cells.
Carcinoma
In vitro determination of basement membrane invasion predicts liver metastases in human gastrointestinal carcinoma.
Carcinoma
In vivo and in vitro antitumor effect of a unique nutrient mixture on lung cancer cell line A-549.
Carcinoma
In vivo characterization of activatable cell penetrating peptides for targeting protease activity in cancer.
Carcinoma
Increased cell-substratum adhesion, and decreased gelatinase secretion and cell growth, induced by E-cadherin transfection of human colon carcinoma cells.
Carcinoma
Increased expression and activation of gelatinolytic matrix metalloproteinases is associated with the progression and recurrence of human cervical cancer.
Carcinoma
Increased expression and activation of matrix metalloproteinase-2 (MMP-2) in O-1N: hamster oral squamous cell carcinoma with high potential lymph node metastasis.
Carcinoma
Increased expression of matrix metalloproteinase 7 and 9 and membrane type 1-matrix metalloproteinase in esophageal squamous cell carcinomas.
Carcinoma
Increased expression of matrix metalloproteinase-2 (MMP-2) predicts tumour recurrence and unfavourable outcome in non-small cell lung cancer.
Carcinoma
Increased expression of matrix metalloproteinase-2 and 9 and human papilloma virus infection are associated with malignant transformation of sinonasal inverted papilloma.
Carcinoma
Increased expression of matrix metalloproteinase-2 in oral cells after short-term stimulation and long-term usage of areca quid.
Carcinoma
Increased expression of the Mr 72,000 type IV collagenase in human colonic adenocarcinoma.
Carcinoma
Increased expression of tissue inhibitor of metalloproteinase-2 in clear cell carcinoma of the ovary.
Carcinoma
Increased invasion and matrix metalloproteinase-2 expression by Snail-induced mesenchymal transition in squamous cell carcinomas.
Carcinoma
Increased matrix metalloproteinase 2 concentration and transcript expression in advanced colorectal carcinomas.
Carcinoma
Increased matrix metalloproteinase-2 expression and reduced tissue factor pathway inhibitor-2 expression correlate with angiogenesis and early postoperative recurrence of pancreatic carcinoma.
Carcinoma
Increased matrix metalloproteinase-9 secretion in short-term tissue cultures of prostatic tumor cells.
Carcinoma
Increased matrix metalloproteinases 2 and 9 and tissue inhibitor of matrix metalloproteinase 2 expression is associated with progression from vulvar intraepithelial neoplasia to invasive carcinoma.
Carcinoma
Induction of M(r) 92,000 type IV collagenase expression in a squamous cell carcinoma cell line by fibroblasts.
Carcinoma
Influence of angiogenetic factors and matrix metalloproteinases upon tumour progression in non-small-cell lung cancer.
Carcinoma
Influence of cytokines and growth factors on matrix metalloproteinase-2 production and invasion of human renal cancer.
Carcinoma
Influence of lymphatic endothelial cells on proliferation and invasiveness of esophageal carcinoma cells in vitro and lymphangiogenesis in vivo.
Carcinoma
Influence of organ environment on extracellular matrix degradative activity and metastasis of human colon carcinoma cells.
Carcinoma
Infrequent stromal expression of gelatinase A and intact basement membrane in intraductal neoplasms of the pancreas.
Carcinoma
Inhibition activity of sulfated polysaccharide of Sepiella maindroni ink on matrix metalloproteinase (MMP)-2.
Carcinoma
Inhibition of cervical lymph node metastasis by marimastat (BB-2516) in an orthotopic oral squamous cell carcinoma implantation model.
Carcinoma
Inhibition of cyclooxygenase-2 suppresses invasiveness of oral squamous cell carcinoma cell lines via down-regulation of matrix metalloproteinase-2 and CD44.
Carcinoma
Inhibition of cyclooxygenase-2 suppresses the invasiveness of oral squamous cell carcinoma cell lines via down-regulation of matrix metalloproteinase-2 production and activation.
Carcinoma
Inhibition of gelatinase A (MMP-2) by batimastat and captopril reduces tumor growth and lung metastases in mice bearing Lewis lung carcinoma.
Carcinoma
Inhibition of matrix metalloproteinase-2 expression and bladder carcinoma metastasis by halofuginone.
Carcinoma
Inhibition of matrix metalloproteinase-2 modulates malignant behaviour of oral squamous cell carcinoma cells.
Carcinoma
Inhibition of tumor-cell invasion and gelatinase production in metastatic human gastric-carcinoma cells by retinoic Acid and bestatin.
Carcinoma
Inhibitory effects of ubenimex (bestatin) on the invasion of uterine cervical carcinoma cells and their production and activation of gelatinase A.
Carcinoma
Inonotus obliquus-derived polysaccharide inhibits the migration and invasion of human non-small cell lung carcinoma cells via suppression of MMP-2 and MMP-9.
Carcinoma
Inostamycin, an inhibitor of cytidine 5'-diphosphate 1,2-diacyl-sn-glycerol (CDP-DG): inositol transferase, suppresses invasion ability by reducing productions of matrix metalloproteinase-2 and -9 and cell motility in HSC-4 tongue carcinoma cell line.
Carcinoma
Intratumoral heterogeneity and inverse correlation between expression of E-cadherin and collagenase type IV in human gastric carcinomas.
Carcinoma
Introduction of basic fibroblast growth factor gene into mouse renal cell carcinoma cell line enhances its metastatic potential.
Carcinoma
Invasive ability of human renal cell carcinoma cell line Caki-2 is accelerated by gamma-aminobutyric acid, via sustained activation of ERK1/2 inducible matrix metalloproteinases.
Carcinoma
Involvement of DPPIV/CD26 in epithelial morphology and suppressed invasive ability in ovarian carcinoma cells.
Carcinoma
Involvement of Ets-1 transcription factor in inducing matrix metalloproteinase-2 expression by epithelial-mesenchymal transition in human squamous carcinoma cells.
Carcinoma
Involvement of focal adhesion kinase in cellular invasion of head and neck squamous cell carcinomas via regulation of MMP-2 expression.
Carcinoma
Involvement of matrix metalloproteinase-2 activity in invasion and metastasis of pancreatic carcinoma.
Carcinoma
Isolation and characterization of a high molecular weight type IV collagenase isolated from human carcinoma tissue.
Carcinoma
Knockdown of Angiopoietin-2 Suppresses Metastasis in Human Pancreatic Carcinoma by Reduced Matrix Metalloproteinase-2.
Carcinoma
Laminin-5 gamma2 chain and matrix metalloproteinase-2 expression in the neoplastic changes of uterine cervical squamous epithelium.
Carcinoma
Leptin acts on neoplastic behavior and expression levels of genes related to hypoxia, angiogenesis, and invasiveness in oral squamous cell carcinoma.
Carcinoma
Leucine-rich repeat-containing G-protein-coupled receptor 5 is associated with invasion, metastasis, and could be a potential therapeutic target in human gastric cancer.
Carcinoma
Levels of matrix metalloproteases in bladder cancer correlate with tumor grade and invasion.
Carcinoma
Levels of neutrophil gelatinase-assosciated lipocalin in patients with head and neck squamous cell carcinoma in Indian population from Haryana state.
Carcinoma
Localization of matrix metalloproteinase 9 (92-kilodalton gelatinase/type IV collagenase = gelatinase B) in osteoclasts: implications for bone resorption.
Carcinoma
Localization of messenger RNA for Mr 72,000 and 92,000 type IV collagenases in human skin cancers by in situ hybridization.
Carcinoma
Localization of the 92 kd gelatinase mRNA in squamous cell and adenocarcinomas of the lung using in situ hybridization.
Carcinoma
Low concentrations of the recombinant toxin protein rLj-RGD3 suppress TNF-?-induced human renal carcinoma cell invasion.
Carcinoma
Lymph node micrometastasis and its correlation with MMP-2 expression in gastric carcinoma.
Carcinoma
Marked acceleration of the metastatic phenotype of a rat bladder carcinoma cell line by the expression of human gelatinase A.
Carcinoma
Matrilysin (MMP-7) promotes invasion of ovarian cancer cells by activation of progelatinase.
Carcinoma
Matrix metallopeptidase 2 (MMP2) mediates MHC class I polypeptide-related sequence A (MICA) shedding in renal cell carcinoma.
Carcinoma
Matrix metalloproteinase (MMP-2 and MMP-9) and steroid receptor expressions in feline mammary tumors.
Carcinoma
Matrix metalloproteinase 2 and matrix metalloproteinase 9 expression in human oral squamous cell carcinoma and the effect of protein kinase C inhibitors: preliminary observations.
Carcinoma
Matrix metalloproteinase 2 immunoreactive protein appears early in cervical epithelial dedifferentiation.
Carcinoma
Matrix metalloproteinase 9 expression in primary human prostatic adenocarcinoma and benign prostatic hyperplasia.
Carcinoma
Matrix metalloproteinase expression in normal skin associated with basal cell carcinoma and in distal skin from the same patients.
Carcinoma
Matrix metalloproteinase-2 (MMP-2): A major player in the progression of systemic malignancies besides endometrial serous carcinomas.
Carcinoma
Matrix metalloproteinase-2 and -14 in p16-positive and -negative HNSCC after exposure To 5-FU and docetaxel In Vitro.
Carcinoma
Matrix metalloproteinase-2 and -9 activities correlate with the disease-free survival of oral squamous cell carcinoma patients.
Carcinoma
Matrix metalloproteinase-2 and -9 and tissue inhibitor of metalloproteinase-1 and -2 in sera and urine of patients with renal carcinoma.
Carcinoma
Matrix metalloproteinase-2 and -9 in the sera and in the urine of human oncocytoma and renal cell carcinoma.
Carcinoma
Matrix metalloproteinase-2 and matrix metalloproteinase-9 codistribute with transcription factors RUNX1/AML1 and ETV5/ERM at the invasive front of endometrial and ovarian carcinoma.
Carcinoma
Matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 expression and synthetic matrix metalloproteinase-2 inhibitor binding in ovarian carcinomas and tumor cell lines.
Carcinoma
Matrix metalloproteinase-2 expression in laryngeal preneoplastic and neoplastic lesions.
Carcinoma
Matrix metalloproteinase-2 immunoreactive protein as a prognostic marker in bladder cancer.
Carcinoma
Matrix metalloproteinase-2 status in stromal fibroblasts, not in tumor cells, is a significant prognostic factor in non-small-cell lung cancer.
Carcinoma
Matrix metalloproteinase-2, squamous cell carcinoma antigen, and tissue polypeptide-specific antigen expression in Egyptian patients with cervical carcinoma: Relationship with prognosis.
Carcinoma
Matrix metalloproteinase-9 from bone marrow-derived cells contributes to survival but not growth of tumor cells in the lung microenvironment.
Carcinoma
Matrix metalloproteinase-9 is a prognostic marker to predict survival of patients who underwent surgery due to rectal carcinoma.
Carcinoma
Matrix metalloproteinases (MMPs) and inhibitor of metalloproteinases (TIMP) mRNA and protein expression in laryngeal squamous cell carcinoma.
Carcinoma
Matrix metalloproteinases 2 and 9 immunoexpression in prostate carcinoma at the positive margin of radical prostatectomy specimens.
Carcinoma
Matrix metalloproteinases and their inhibitors: correlation with invasion and metastasis in oral cancer.
Carcinoma
Matrix metalloproteinases contribute distinct roles in neuroendocrine prostate carcinogenesis, metastasis, and angiogenesis progression.
Carcinoma
Matrix metalloproteinases expressed in squamous cell carcinoma of the oral cavity: correlation with clinicopathologic features and neo-adjuvant chemotherapy response.
Carcinoma
Matrix-metalloproteinases 1, 2, and 3 and their tissue inhibitors 1 and 2 in benign and malignant breast lesions: an in situ hybridization study.
Carcinoma
Matrix-metalloproteinases and their inhibitors in plasma and tumor tissue of patients with renal cell carcinoma.
Carcinoma
May High MMP-2 and TIMP-2 Expressions Increase or Decrease the Aggressivity of Oral Cancer?
Carcinoma
Membrane-type matrix metalloproteinase (MT-MMP) gene is expressed in stromal cells of human colon, breast, and head and neck carcinomas.
Carcinoma
Membrane-type matrix metalloproteinase expression and matrix metalloproteinase-2 activation in primary human ovarian epithelial carcinoma cells.
Carcinoma
Metalloproteinase-2 expression correlates with aggressiveness of cutaneous squamous cell carcinomas.
Carcinoma
Metalloproteinases and their inhibitors: Influence on tumor invasiveness and metastasis formation in head and neck squamous cell carcinomas.
Carcinoma
Metalloproteinases and tissue inhibitor of metalloproteinase 1 (TIMP-1) in endometrial flushings from pre- and post-menopausal women and from women with endometrial adenocarcinoma.
Carcinoma
Metastatic dissemination of human ovarian epithelial carcinoma is promoted by alpha2beta1-integrin-mediated interaction with type I collagen.
Carcinoma
miR-29b inhibits the progression of esophageal squamous cell carcinoma by targeting MMP-2.
Carcinoma
MMP production in human fibrosarcoma cells and their invasiveness are regulated by group IB secretory phospholipase A2 receptor-mediated activation of cytosolic phospholipase A2.
Carcinoma
MMP-1 and MMP-2 in the cervix uteri in different steps of malignant transformation--an immunohistochemical study.
Carcinoma
MMP-2 and DcR3 expression in esophageal cancer tissue and correlation with patient survival.
Carcinoma
MMP-2 and MMP-9 as prognostic markers for the early detection of urinary bladder cancer.
Carcinoma
MMP-2 and TIMP-2 expression correlates with poor prognosis in cervical carcinoma--a clinicopathologic study using immunohistochemistry and mRNA in situ hybridization.
Carcinoma
MMP-2 together with MMP-9 overexpression correlated with lymph node metastasis and poor prognosis in early gastric carcinoma.
Carcinoma
MMP-2, TIMP-1, E-cadherin, and beta-catenin expression in endometrial serous carcinoma compared with low-grade endometrial endometrioid carcinoma and proliferative endometrium.
Carcinoma
MMP-9 secretion and MMP-2 activation distinguish invasive and metastatic sublines of a mouse mammary carcinoma system showing epithelial-mesenchymal transition traits.
Carcinoma
Modulation of cell growth and matrix metalloproteinase-2 activation of oral squamous cell carcinoma as a function of culture condition with type I collagen.
Carcinoma
Modulation of human renal cell carcinoma 786-0 MMP-2 and MMP-9 activity by inhibitors and inducers in vitro.
Carcinoma
Modulation of the invasive phenotype of human colon carcinoma cells by organ specific fibroblasts of nude mice.
Carcinoma
Molecular pathways involved in crosstalk between cancer cells, osteoblasts and osteoclasts in the invasion of bone by oral squamous cell carcinoma.
Carcinoma
mRNA expression of matrix metalloproteases and their inhibitors differs in subtypes of renal cell carcinomas.
Carcinoma
MT1-MMP and MMP-2 mRNA expression in human ovarian tumors: possible implications for the role of desmoplastic fibroblasts.
Carcinoma
MT1-MMP correlates with MMP-2 activation potential seen after epithelial to mesenchymal transition in human breast carcinoma cells.
Carcinoma
Neutrophil Gelatinase Associated Lipocalin is an Independent Predictor of Poor Prognosis in Cases of Papillary Renal Cell Carcinoma.
Carcinoma
Nicotinamide N-methyltransferase Induces Cellular Invasion through Activating Matrix Metalloproteinase-2 Expression in Clear Cell Renal Cell Carcinoma Cells.
Carcinoma
nm23-H1 suppresses invasion of oral squamous cell carcinoma-derived cell lines without modifying matrix metalloproteinase-2 and matrix metalloproteinase-9 expression.
Carcinoma
Novel 19F activatable probe for the detection of matrix metalloprotease-2 activity by MRI/MRS.
Carcinoma
O-6-methylguanine-DNA Methyltransferase Inhibits Gastric Carcinoma Cell Migration and Invasion by Downregulation of Matrix Metalloproteinase 2.
Carcinoma
Occurrence of an active form of gelatinase in human gastric and colorectal carcinoma tissues.
Carcinoma
Of humans and hamsters: A comparative evaluation of carcinogen activation, DNA damage, cell proliferation, apoptosis, invasion, and angiogenesis in oral cancer patients and hamster buccal pouch carcinomas.
Carcinoma
Oral and IV Dosages of Doxorubicin-Methotrexate loaded- Nanoparticles Inhibit Progression of Oral Cancer by Down- Regulation of Matrix Methaloproteinase 2 Expression in Vivo.
Carcinoma
Oral submucous fibrosis stimulates invasion and epithelial-mesenchymal transition in oral squamous cell carcinoma by activating MMP-2 and IGF-IR.
Carcinoma
Ovarian carcinoma cells in serous effusions show altered MMP-2 and TIMP-2 mRNA levels.
Carcinoma
Ovarian carcinoma regulation of matrix metalloproteinase-2 and membrane type 1 matrix metalloproteinase through beta1 integrin.
Carcinoma
Overexpression of Aurora-A enhances invasion and matrix metalloproteinase-2 expression in esophageal squamous cell carcinoma cells.
Carcinoma
Overexpression of MMP-2 and MMP-9 in squamous cell carcinomas of immunosuppressed patients.
Carcinoma
Overexpression of MMP-2 in laryngeal squamous cell carcinoma: a potential indicator for poor prognosis.
Carcinoma
p21(WAF-1/CIP-1), a downstream regulator of functional p53 loss, in transitional cell carcinoma of urothelium.
Carcinoma
p38 mitogen-activated protein kinase-driven MAPKAPK2 regulates invasion of bladder cancer by modulation of MMP-2 and MMP-9 activity.
Carcinoma
Pancreatic Stellate Cells Activation and Matrix Metallopeptidase 2 Expression Correlate With Lymph Node Metastasis in Pancreatic Carcinoma.
Carcinoma
Paracrine communication between malignant and non-malignant prostate epithelial cells in culture alters growth rate, matrix protease secretion and in vitro invasion.
Carcinoma
Participation of fibroblasts in MMP-2 binding and activation on the surface of oral squamous cell carcinoma cells.
Carcinoma
PEA3 is the second Ets family transcription factor involved in tumor progression in ovarian carcinoma.
Carcinoma
Periacinar Retraction Clefting in Nonneoplastic and Neoplastic Prostatic Glands: Artifact or Molecular Involvement.
Carcinoma
Periostin promotes migration and invasion of renal cell carcinoma through the integrin/focal adhesion kinase/c-Jun N-terminal kinase pathway.
Carcinoma
Peritumoral Clefting and Expression of MMP-2 and MMP-9 in Basal Cell Carcinoma of the Skin.
Carcinoma
Phenotypes of human esophageal squamous cell carcinoma based on matrix metalloproteinase production.
Carcinoma
Pinosylvin reduced migration and invasion of oral cancer carcinoma by regulating matrix metalloproteinase-2 expression and extracellular signal-regulated kinase pathway.
Carcinoma
PinX1 serves as a potential prognostic indicator for clear cell renal cell carcinoma and inhibits its invasion and metastasis by suppressing MMP-2 via NF-?B-dependent transcription.
Carcinoma
Pituitary tumor-transforming 1 expression in laryngeal cancer and its association with prognosis.
Carcinoma
Plasma levels of matrix metalloproteinases 2 and 9 correlate with histological grade in breast cancer patients.
Carcinoma
Prediction of metastasis in oral squamous cell carcinoma through phenotypic evaluation and gene expression of E-cadherin, ?-catenin, matrix metalloproteinase-2, and matrix metalloproteinase-9 biomarkers with clinical correlation.
Carcinoma
Prediction of prognosis in gallbladder carcinoma by CD147 and MMP-2 immunohistochemistry.
Carcinoma
Preliminary evaluation for Bit1 as a potential biomarker for squamous cell carcinoma and adenocarcinoma of esophagus.
Carcinoma
Proanthocyanidins from grape seeds inhibit expression of matrix metalloproteinases in human prostate carcinoma cells, which is associated with the inhibition of activation of MAPK and NF kappa B.
Carcinoma
Production of extracellular matrix-degrading proteinases by primary cultures of human epithelial ovarian carcinoma cells.
Carcinoma
Production of matrix metalloproteinase 2 (gelatinase/type IV collagenase) and 3 (stromelysin) by cultured oral squamous cell carcinoma.
Carcinoma
Production of matrix metalloproteinase-2 and metalloproteinase-3 related to malignant behavior of esophageal carcinoma. A clinicopathologic study.
Carcinoma
Production of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human breast carcinomas.
Carcinoma
Progelatinase A mRNA expression in cell lines derived from tumors in patients with metastatic renal cell carcinoma correlates inversely with survival.
Carcinoma
Prognosis of gastric carcinoma revealed by interactions between tumor cells and basement membrane.
Carcinoma
Prognostic analysis of clinicopathologic factors in 49 patients with diffuse malignant peritoneal mesothelioma treated with cytoreductive surgery and intraperitoneal hyperthermic perfusion.
Carcinoma
Prognostic molecular markers in head and neck squamous cell carcinoma in a New Zealand population: matrix metalloproteinase-2 and sialyl Lewis x antigen.
Carcinoma
Prognostic relevance of serum levels of the angiogenic peptide bFGF in advanced carcinoma of the head and neck treated by primary radiochemotherapy.
Carcinoma
Prognostic significance of matrix metalloproteinases 2 and 9 in endometrial cancer.
Carcinoma
Prognostic significance of matrix metalloproteinases-2 activation ratio in renal cell carcinoma.
Carcinoma
Prognostic significance of stromal metalloproteinase-2 in ovarian adenocarcinoma and its relation to carcinoma progression.
Carcinoma
Prognostic significance of TIMP-2, MMP-2, and MMP-9 on high-grade serous ovarian carcinoma using digital image analysis.
Carcinoma
Prognostic stratification of stage IIIA pN2 non-small cell lung cancer by hierarchical clustering analysis of tissue microarray immunostaining data: an Alpe Adria Thoracic Oncology Multidisciplinary Group study (ATOM 014).
Carcinoma
Prognostic value of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in bladder carcinoma.
Carcinoma
Prognostic value of matrix metalloproteinases (MMP-2 and MMP-9) in patients with lymph node-negative breast carcinoma.
Carcinoma
Prognostic value of MMP-2 for patients with ovarian epithelial carcinoma: a systematic review and meta-analysis.
Carcinoma
Prognostic value of MMP-2, -9 and TIMP-1,-2 immunoreactive protein at the invasive front in advanced head and neck squamous cell carcinomas.
Carcinoma
Prognostic values of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 expression in bladder cancer.
Carcinoma
Prominent expression of metalloproteinases in early stages of ovarian tumorigenesis.
Carcinoma
Prostate carcinoma and green tea: (-)epigallocatechin-3-gallate inhibits inflammation-triggered MMP-2 activation and invasion in murine TRAMP model.
Carcinoma
Prostate carcinoma and green tea: PSA-triggered basement membrane degradation and MMP-2 activation are inhibited by (-)epigallocatechin-3-gallate.
Carcinoma
Protein Expression of MMP-2 and MT1-MMP in Actinic Keratosis, Squamous Cell Carcinoma of the Skin, and Basal Cell Carcinoma.
Carcinoma
Proteolytic enzymes in tumor metastasis. II. Collagenase type IV activity in subcellular fractions of cloned tumor cell populations.
Carcinoma
Purification and characterization of a two-chain form of tissue inhibitor of metalloproteinases (TIMP) type 2 and a low molecular weight TIMP-like protein.
Carcinoma
Quantitative Assessment of the Effects of MMP-2 Polymorphisms on Lung Carcinoma Risk.
Carcinoma
Ras levels and metalloproteinase activity in normal versus neoplastic rat mammary tissues.
Carcinoma
Recombinant EGFR/MMP-2 bi-targeted fusion protein markedly binding to non-small-cell lung carcinoma and exerting potent therapeutic efficacy.
Carcinoma
Redox-regulation of gelatinases during growth of cisplatin-sensitive and resistant Guerin carcinoma.
Carcinoma
Reduced expression of tissue inhibitor of metalloproteinase in nodal metastasis of stomach cancer.
Carcinoma
Regulation of gelatinase production in metastatic renal cell carcinoma by organ-specific fibroblasts.
Carcinoma
Regulation of the Mr 72,000 type IV collagenase by the type I insulin-like growth factor receptor.
Carcinoma
Regulatory effect of MiR103 on proliferation, EMT and invasion of oral squamous carcinoma cell through SALL4.
Carcinoma
Relationship between metalloprotease expression in tumour and stromal cells and aggressive behaviour in prostate carcinoma: Simultaneous high-throughput study of multiple metalloproteases and their inhibitors using tissue array analysis of radical prostatectomy samples.
Carcinoma
Relationship between the Expression of Matrix Metalloproteinase and Clinicopathologic Features in Oral Squamous Cell Carcinoma.
Carcinoma
Relationships Between Immunophenotype, Ki-67 Index, Microvascular Density, Ep-CAM/P-cadherin, and MMP-2 Expression in Early-stage Invasive Ductal Breast Cancer.
Carcinoma
Relative expression of E-cadherin and type IV collagenase genes predicts disease outcome in patients with resectable pancreatic carcinoma.
Carcinoma
Relative expression of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in mouse renal cell carcinoma cells regulates their metastatic potential.
Carcinoma
Role of functional polymorphism of matrix metalloproteinase-2 (-1306 C/T and -168 G/T) and MMP-9 (-1562 C/T) promoter in oral submucous fibrosis and head and neck squamous cell carcinoma in an Indian population.
Carcinoma
Role of immunohistochemical overexpression of matrix metalloproteinases MMP-2 and MMP-11 in the prognosis of death by ovarian cancer.
Carcinoma
Role of matrix metalloproteinase-9 in in vitro invasion of esophageal carcinoma cells.
Carcinoma
Role of matrix metalloproteinase-9 in the basement membrane destruction of superficial urothelial carcinomas.
Carcinoma
Role of membrane type 1-matrix metalloproteinase and gelatinase A in head and neck squamous cell carcinoma invasion in vitro.
Carcinoma
Role of siRNA silencing of MMP-2 gene on invasion and growth of laryngeal squamous cell carcinoma.
Carcinoma
ROS Production and Distribution: A New Paradigm to Explain the Differential Effects of X-ray and Carbon Ion Irradiation on Cancer Stem Cell Migration and Invasion.
Carcinoma
S100A4 mediated cell invasion and metastasis of esophageal squamous cell carcinoma via the regulation of MMP-2 and E-cadherin activity.
Carcinoma
S100A8/A9 regulates MMP-2 expression and invasion and migration by carcinoma cells.
Carcinoma
Salivary MMP-1, MMP-2, MMP-3 and MMP-13 Levels in Patients with Oral Lichen Planus and Squamous Cell Carcinoma
Carcinoma
Secretion of gelatinases by human pancreatic cancer cell lines: lack of correlation with invasive ability.
Carcinoma
Selective gelatinase inhibitor peptide is effective in targeting tongue carcinoma cell tumors in vivo.
Carcinoma
Serum Level of Matrix Metalloproteinase-2 and -9 in Patients with Laryngeal Squamous Cell Carcinoma and Clinical Significance.
Carcinoma
Serum levels of matrix metalloproteinase-2 and -9 in patients with head and neck squamous cell carcinoma.
Carcinoma
Serum matrix metalloproteinase 2 and tissue inhibitor of matrix metalloproteinases 2 in esophageal cancer patients.
Carcinoma
Serum metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in lung carcinoma patients.
Carcinoma
Shedding of membrane type 1 matrix metalloproteinase in a human breast carcinoma cell line.
Carcinoma
Significance of matrix metalloproteinases and tissue inhibitors of metalloproteinase expression in the recurrence of superficial transitional cell carcinoma of the bladder.
Carcinoma
Significance of MMP-2 expression in prostate cancer: an immunohistochemical study.
Carcinoma
Similarities of in situ mRNA expression between gelatinase A (MMP-2) and type I procollagen in human gastrointestinal carcinoma: comparison with granulation tissue reaction.
Carcinoma
Skp2 Regulates the Expression of MMP-2 and MMP-9, and Enhances the Invasion Potential of Oral Squamous Cell Carcinoma.
Carcinoma
Snail, Slug, and Smad-interacting protein 1 as novel parameters of disease aggressiveness in metastatic ovarian and breast carcinoma.
Carcinoma
Sodium caffeate induces endothelial cell apoptosis and inhibits VEGF expression in cancer cells.
Carcinoma
Soluble EMMPRIN (extra-cellular matrix metalloproteinase inducer) stimulates the migration of HEp-2 human laryngeal carcinoma cells, accompanied by increased MMP-2 production in fibroblasts.
Carcinoma
Squamous cell carcinoma growth in mice and in culture is regulated by c-Jun and its control of matrix metalloproteinase-2 and -9 expression.
Carcinoma
Stromal cells play a role in cervical cancer progression mediated by MMP-2 protein.
Carcinoma
Stromal expression of 72 kda type IV collagenase (MMP-2) and TIMP-2 mRNAs in colorectal neoplasia.
Carcinoma
Stromal fibroblasts adjacent to invasive thyroid tumors: expression of gelatinase A but not stromelysin 3 mRNA.
Carcinoma
Strong association of the tissue inhibitor of metalloproteinase-2 polymorphism with an increased risk of oral squamous cell carcinoma in Europeans.
Carcinoma
Strong significant correlation between MMP-9 and systemic symptoms in patients with localized renal cell carcinoma.
Carcinoma
Substance P accelerates the progression of human esophageal squamous cell carcinoma via MMP-2, MMP-9, VEGF-A, and VEGFR1 overexpression.
Carcinoma
Suppression of matrix metalloproteinase-2 via RNA interference inhibits pancreatic carcinoma cell invasiveness and adhesion.
Carcinoma
Survivin, bcl-2 and matrix metalloproteinase-2 enhance progression of clear cell- and serous-type ovarian carcinomas.
Carcinoma
Synthetic emmprin peptides inhibit tumor cell-fibroblast interaction-stimulated upregulation of MMP-2 and tumor cell invasion.
Carcinoma
Taxifolin inhibits the scar cell carcinoma growth by inducing apoptosis, cell cycle arrest and suppression of PI3K/AKT/mTOR pathway.
Carcinoma
The aqueous extract of Prunella vulgaris suppresses cell invasion and migration in human liver cancer cells by attenuating matrix metalloproteinases.
Carcinoma
The clinical role of phospholipase A2 isoforms in advanced-stage ovarian carcinoma.
Carcinoma
The Effect of TGF-beta(2) on MMP-2 Production and Activity in Highly Metastatic Human Bladder Carcinoma Cell Line 5637.
Carcinoma
The enamel matrix derivative (Emdogain) enhances human tongue carcinoma cells gelatinase production, migration and metastasis formation.
Carcinoma
The expression and clinical significance of metastasis suppressor gene and matrix metalloproteinase-2 in esophageal squamous cell of carcinoma.
Carcinoma
The Expression and Clinical Significance of TGF-B1 and MMP2 in Human Renal Clear Cell Carcinoma.
Carcinoma
The expression of matrix metalloproteinases in intrahepatic cholangiocarcinoma, hilar (Klatskin tumor), middle and distal extrahepatic cholangiocarcinoma, gallbladder cancer, and ampullary carcinoma: role of matrix metalloproteinases in tumor progression and prognosis.
Carcinoma
The expression of matrix metalloproteinases-2 and -9 and their tissue inhibitor 2 in pancreatic ductal and ampullary carcinoma and their relation to angiogenesis and clinicopathological parameters.
Carcinoma
The expression of six biomarkers in the four most common ovarian cancers: correlation with clinicopathological parameters.
Carcinoma
The expression of STAT3, BCL-XL and MMP-2 proteins in colon adenocarcinomas and their relationship with prognostic factors.
Carcinoma
The High Mobility Group A1 (HMGA1) gene is highly overexpressed in human uterine serous carcinomas and carcinosarcomas and drives Matrix Metalloproteinase-2 (MMP-2) in a subset of tumors.
Carcinoma
The immunohistochemical characterization of MMP-2, MMP-10, TIMP-1, TIMP-2, and podoplanin in oral squamous cell carcinoma.
Carcinoma
The influence of matrix metalloproteinase-2, -9, and -12 promoter polymorphisms on Iranian patients with oesophageal squamous cell carcinoma.
Carcinoma
The inhibitory effects of capillarisin on cell proliferation and invasion of prostate carcinoma cells.
Carcinoma
The Mechanism of Asparagine Endopeptidase in the Progression of Malignant Tumors: A Review.
Carcinoma
The prognostic value of metalloproteinases and angiogenic factors in ovarian carcinoma.
Carcinoma
The prognostic value of p53, Ki-67 and matrix metalloproteinases MMP-2 and MMP-9 in transitional cell carcinoma of the renal pelvis and ureter.
Carcinoma
The prognostic value of the expression of collagenase IV, cathepsin D and metallothionein in squamous cell carcinomas of the skin determined by immunohistochemistry.
Carcinoma
The role of matrix metalloproteinases 2 and 9 during rat tongue carcinogenesis induced by 4-nitroquinoline 1-oxide.
Carcinoma
The role of MMP-2 and MMP-9 as prognostic markers in the early stages of tongue squamous cell carcinoma.
Carcinoma
The role of MMP-2 and MMP-9 in the metastasis and development of hypopharyngeal carcinoma.
Carcinoma
The role of p53 protein and MMP-2 tumor/stromal cells expression on progressive growth of ovarian neoplasms.
Carcinoma
Therapy of head and neck squamous cell carcinoma with replicative adenovirus expressing tissue inhibitor of metalloproteinase-2 and chemoradiation.
Carcinoma
Thymoquinone inhibits metastasis of renal cell carcinoma cell 786-O-SI3 associating with downregulation of MMP-2 and u-PA and suppression of PI3K/Src signaling.
Carcinoma
Tissue and serum metalloproteinase (MMP-2) expression in advanced ovarian serous cystoadenocarcinomas: clinical and prognostic implications.
Carcinoma
Tissue inhibitor of metalloproteinase-2 as a multifunctional molecule of which the expression is associated with adverse prognosis of patients with urothelial bladder carcinomas.
Carcinoma
Tissue levels of matrix metalloproteinases MMP-2 and MMP-9 are related to the overall survival of patients with gastric carcinoma.
Carcinoma
Tissue MMP-2 and MMP-9 [corrected] are better prognostic factors than serum MMP-2/TIMP-2--complex or TIMP-1 [corrected] in stage [corrected] I-III lung carcinoma.
Carcinoma
Transcriptional expression of the genes implicated in angiogenesis and tumor invasion in cervical carcinomas.
Carcinoma
Treatment of epigallocatechin-3-gallate inhibits matrix metalloproteinases-2 and -9 via inhibition of activation of mitogen-activated protein kinases, c-jun and NF-kappaB in human prostate carcinoma DU-145 cells.
Carcinoma
Tumor-specific urinary matrix metalloproteinase fingerprinting: identification of high molecular weight urinary matrix metalloproteinase species.
Carcinoma
Type IV collagenase and immunostaining of type IV collagen in human thyroid tumors.
Carcinoma
Upregulated EMMPRIN/CD147 might contribute to growth and angiogenesis of gastric carcinoma: a good marker for local invasion and prognosis.
Carcinoma
Upregulated matrix metalloproteinase-2 and downregulated tissue factor pathway inhibitor-2 are risk factors for lymph node metastasis and perineural invasion in pancreatic carcinoma.
Carcinoma
Upregulation of MMP-2 by HMGA1 promotes transformation in undifferentiated, large-cell lung cancer.
Carcinoma
Urinary type IV collagenase: elevated levels are associated with bladder transitional cell carcinoma.
Carcinoma
White matter microglia produce membrane-type matrix metalloprotease, an activator of gelatinase A, in human brain tissues.
Carcinoma
WISP-1 overexpression upregulates cell proliferation in human salivary gland carcinomas via regulating MMP-2 expression.
Carcinoma
XRCC1 serves as a potential prognostic indicator for clear cell renal cell carcinoma and inhibits its invasion and metastasis through suppressing MMP-2 and MMP-9.
Carcinoma
Zymographic analysis of circulating and tissue forms of colon carcinoma gelatinase A (MMP-2) and B (MMP-9) separated by mono- and two-dimensional electrophoresis.
Carcinoma
[An experimental study of matrix metalloproteinase inhibitor BB-94 inhibits the invasion and metastasis of the human salivary adenoid cystic carcinoma in vitro and in vivo]
Carcinoma
[An immunohistochemical double labelling study on type IV collagenase and basement membrane in human colonic carcinoma]
Carcinoma
[Anti-human collagenase type IV expression in preneoplastic lesions and early squamous cell lung carcinoma]
Carcinoma
[Clinicopathological significance of expressions of RECK and MMP-2 in esophageal squamous carcinoma]
Carcinoma
[Correlation between expression of matrix metalloproteinase-2 and angiogenesis in esophageal carcinoma]
Carcinoma
[Correlation of expression of vascular endothelial growth factor and matrix matalloproteinase-2 to invasion of ovarian tumor cells in vitro]
Carcinoma
[Correlations of serous levels of matrix metalloproteinases (MMP-2 and MMP-9) to invasion and metastasis of papillary thyroid carcinoma]
Carcinoma
[Dynamic study on expression of gelatinase A and its natural inhibitor during invasion and metastasis of induced lung cancer in Wistar rats]
Carcinoma
[Effect of bone morphogenetic protein-2 on the expression of membrane Type 1-matrix metalloproteinase in human A549 lung carcinoma cells]
Carcinoma
[Effect of cyclooxygenase-2 inhibitor on expression of matrix metalloproteinase-2 and invasion of tongue squamous cell carcinoma cell line Tca8113].
Carcinoma
[Expression and clinical significance of CD147 and MMP-2 ?in squamous cell carcinoma and adenocarcinoma of the lungs].
Carcinoma
[Expression and clinical significance of matrix metalloproteinase-2 in laryngeal squamous cell carcinoma]
Carcinoma
[Expression and clinicopathologic significance of OPN, CD44v6 and MMP-2 in squamous cell carcinoma and adenocarcinoma of the lung].
Carcinoma
[Expression of FOXC-2 and YB-1 in Gastric Carcinoma and Its Role in Invasion and Metastasis].
Carcinoma
[Expression of matrix metalloproteinase 2 in oral verruvous carcinoma and squamous cell carcinoma]
Carcinoma
[Expression of matrix metalloproteinase-2 and insulin-like growth factor-1 in gastric carcinoma and their clinicopathological significance].
Carcinoma
[Expression of matrix metalloproteinase-2 in hypopharyngeal carcinoma and its clinical significance]
Carcinoma
[Expression of matrix metalloproteinase-2, 9 and it's tissue inhibitor-1, 2 in endometrial carcinoma]
Carcinoma
[Expression of matrix metalloproteinase-2, 9 and their inhibitor-TIMP 1,2 in human squamous cell carcinoma of uterine cervix]
Carcinoma
[Expression of matrix metalloproteinase-2,9 in hypopharyngeal carcinoma and its relationship with lymphatic metastasis]
Carcinoma
[Expression of MMP-2 and E-CD in salivary mucoepidermoid carcinoma and its correlation with infiltration, metastasis and prognosis]
Carcinoma
[Expression of MMP-2 and its clinical significance in cervical squamous carcinoma]
Carcinoma
[Expression of MMP-2 and MMP-9 in non-small-cell lung cancer and their prognostic value.]
Carcinoma
[Expression of nm23/NDPK, integrin, type IV collagenase and uPA in transplanted tumors with various metastatic potential in nude mice and surgical specimens]
Carcinoma
[Expression of S100A4 in esophageal squamous cell carcinoma and its relation to tumor invasion and metastasis]
Carcinoma
[Expressions and clinical significance of vasculogenic mimicry and related protein Mig-7 and MMP-2 in gastric carcinoma].
Carcinoma
[Expressions and significances of CD147, OPN and MMP-2 in oral squamous cell carcinoma].
Carcinoma
[Expressions of CD147, MMP-2 and MMP-9 in laryngeal carcinoma and clinical significance]
Carcinoma
[Expressions of discoidin domain receptor 1 and matrix metalloproteinase 2 in salivary gland adenoid cystic carcinoma and clinical significance].
Carcinoma
[Expressions of MMP-2 and COX-2 mRNA in bladder transitional cell carcinoma and their correlation]
Carcinoma
[Gelatinases A and B and their endogenous regulators in the corpus uteri in squamous cell cervical carcinoma].
Carcinoma
[Helicobacter pylori infection, the invasion and metastasis of the gastric carcinoma, and the expression of MMP-2 and TIMP-2]
Carcinoma
[Inhibitory effect of anti-type IV collagenase intrabody on invasiveness of human pulmonary giant cell carcinoma PG cells in vitro]
Carcinoma
[Inhibitory effects of matrix metalloproteinase (MMP) inhibitor LY52 on expression of MMP-2 and MMP-9 and invasive ability of human ovarian carcinoma cell line SKOV3]
Carcinoma
[Interactions of ovarian carcinoma cells and human peritoneal mesothelial cells involved in matrix metalloproteinases expressions of ovarian carcinoma cells]
Carcinoma
[Interference of HIF-1alpha by RNA reduces the expression of matrix metalloproteinase-2 in human cervical carcinoma HeLa cells]
Carcinoma
[Matrix metalloproteinase-2 concentrations in squamous cell carcinoma of the head and neck and its clinical significance]
Carcinoma
[Matrix metalloproteinase-2 expression and its correlation with mesorectal metastasis in middle and lower rectal cancer]
Carcinoma
[Matrix metalloproteinases (MMP)--MMP-1,-2,-9 and its endogenous activity regulators in transformed by E7 oncogene HPV16 and HPV18 cervical carcinoma cell lines].
Carcinoma
[Matrix metalloproteinases and their tissue inhibitors in malignancies of the female genital tract]
Carcinoma
[miR-143 inhibits proliferation and invasion of hepatocellular carcinoma cells via down-regulation of TLR2 expression].
Carcinoma
[mRNA expression analysis of metastatic markers in clear-cell renal cell carcinoma]
Carcinoma
[New direct assay method of type IV collagenase in tissue homogenate and biochemical role of collagenase against type I, and IV collagens to the invasion of the stomach and lung cancer]
Carcinoma
[Polymorphism of metalloproteinases MMP-1 and MMP-2 in risk of laryngeal cancer].
Carcinoma
[Predictive value of serum levels of basic fibroblast growth factor, vascular endothelial growth factor and matrix metalloproteinase-2 in advanced carcinomas of the head and neck]
Carcinoma
[Relationship of local recurrence with the expression of Survivin and MMP-2 in laryngeal carcinoma and its surgical margins].
Carcinoma
[Relationship of the disturbed balance between matrix metalloproteinases and their tissue inhibitors and the invasion of malignant salivary gland tumours]
Carcinoma
[Role of matrix metalloproteinases (MMPs) in tumor invasion and metastasis: serial studies on MMPs and TIMPs]
Carcinoma
[Role of organ specific fibroblasts in metastasis of human renal cell carcinoma: regulation of type IV collagenase production from human renal cell carcinoma by organ specific fibroblasts]
Carcinoma
[Role of tissue factor in the invasion of cultured human colon carcinoma cells and its correlation with matrix metalloproteinases]
Carcinoma
[Role of type IV collagenase in tumor cell invasion and effect of laminin on invasive potential in bile duct carcinoma]
Carcinoma
[Role of type IV collagene and type IV collagenase in the invasion and metastasis of salivary adenoid cystic carcinoma]
Carcinoma
[Significance of activated matrix metalloproteinase 2 (MMP2) in progression of bladder transitional cell carcinoma]
Carcinoma
[The effect of tissue inhibitor of metalloproteinase-2 gene (TIMP-2 gene) on gastric carcinoma cells in vitro and in vivo]
Carcinoma
[The expression of matrix metalloproteinase-2 and -9 in cervical cancer and a study of their relationship]
Carcinoma
[The expression of matrix metalloproteinases and tissue inhibitor of metalloproteinases in transplanted tumor of salivary adenoid cystic carcinoma cell lines]
Carcinoma
[The expression of MMP-2 and MMP-9 in adenoid cystic carcinoma of lacrimal gland].
Carcinoma
[The expression of MMP-2, -9 in the uterine leiomyoma and its significance in prognosis].
Carcinoma
[The expression of MMP-2, E-cadherin in supraglottic carcinoma and their relationship with cervical lymph nody metastasis]
Carcinoma
[The relation between integrin, type IV collagenase and extracellular matrix in invasion and metastasis of gastric carcinoma]
Carcinoma
[Type IV collagenase expression in human prostate carcinoma cell lines with different metastasis potentials]
Carcinoma in Situ
Biomarker expression in normal fimbriae: Comparison of high- and low-grade serous ovarian carcinoma.
Carcinoma in Situ
Expression profile of epithelial-mesenchymal transition markers in non-muscle-invasive urothelial carcinoma of the bladder: correlation with intravesical recurrence following transurethral resection.
Carcinoma in Situ
[Anti-human collagenase type IV expression in preneoplastic lesions and early squamous cell lung carcinoma]
Carcinoma in Situ
[Dynamic study on expression of gelatinase A and its natural inhibitor during invasion and metastasis of induced lung cancer in Wistar rats]
Carcinoma in Situ
[The expression of matrix metalloproteinase-2 and -9 in cervical cancer and a study of their relationship]
Carcinoma, Acinar Cell
Expression of matrix metalloproteinases MMP-2, MMP-9 and their tissue inhibitors TIMP-1, -2, and -3 in benign and malignant tumours of the salivary gland.
Carcinoma, Adenoid Cystic
Comparative Analysis of P63, Maspin and Matrix Metalloproteinase 2 Expression in Mucoepidermoid Carcinoma and Adenoid Cystic Carcinoma of Salivary Glands.
Carcinoma, Adenoid Cystic
Expression of matrix metalloproteinases (MMPs-2, -7, -9, and -26) and tissue inhibitors of metalloproteinases (TIMPs-1 and -2) in pleomorphic adenomas and adenoid cystic carcinomas.
Carcinoma, Adenoid Cystic
Expression of RECK and MMP-2 in salivary adenoid cystic carcinoma: Correlation with tumor progression and patient prognosis.
Carcinoma, Adenoid Cystic
[An experimental study of matrix metalloproteinase inhibitor BB-94 inhibits the invasion and metastasis of the human salivary adenoid cystic carcinoma in vitro and in vivo]
Carcinoma, Adenoid Cystic
[Expressions of discoidin domain receptor 1 and matrix metalloproteinase 2 in salivary gland adenoid cystic carcinoma and clinical significance].
Carcinoma, Adenoid Cystic
[Role of type IV collagene and type IV collagenase in the invasion and metastasis of salivary adenoid cystic carcinoma]
Carcinoma, Adenoid Cystic
[The expression of matrix metalloproteinases and tissue inhibitor of metalloproteinases in transplanted tumor of salivary adenoid cystic carcinoma cell lines]
Carcinoma, Adenoid Cystic
[The expression of MMP-2 and MMP-9 in adenoid cystic carcinoma of lacrimal gland].
Carcinoma, Adenosquamous
[Expression of MMP-2 and MMP-9 in non-small-cell lung cancer and their prognostic value.]
Carcinoma, Basal Cell
Desmoplastic basal cell carcinomas possess unique basement membrane-degrading properties.
Carcinoma, Basal Cell
Differential expression of matrix metalloproteinase (MMP)-2, MMP-9 and tissue inhibitor of metalloproteinase (TIMP)-1 and TIMP-2 in non-melanoma skin cancer: implications for tumour progression.
Carcinoma, Basal Cell
Differential expression of matrix metalloproteinase-2 by fibroblasts in co-cultures with keratinocytes, basal cell carcinoma and melanoma.
Carcinoma, Basal Cell
Expression of 92-kDa type IV collagenase mRNA by eosinophils associated with basal cell carcinoma.
Carcinoma, Basal Cell
Expression of gelatinase A and TIMP-2 mRNAs in desmoplastic fibroblasts in both mammary carcinomas and basal cell carcinomas of the skin.
Carcinoma, Basal Cell
Localization of messenger RNA for Mr 72,000 and 92,000 type IV collagenases in human skin cancers by in situ hybridization.
Carcinoma, Basal Cell
Matrix metalloproteinase expression in normal skin associated with basal cell carcinoma and in distal skin from the same patients.
Carcinoma, Basal Cell
Peritumoral Clefting and Expression of MMP-2 and MMP-9 in Basal Cell Carcinoma of the Skin.
Carcinoma, Basal Cell
Protein Expression of MMP-2 and MT1-MMP in Actinic Keratosis, Squamous Cell Carcinoma of the Skin, and Basal Cell Carcinoma.
Carcinoma, Ductal
Epidermal growth factor receptor-mediated regulation of matrix metalloproteinase-2 and matrix metalloproteinase-9 in MCF-7 breast cancer cells.
Carcinoma, Ductal
Expression of cyclooxygenase-2 and its relation to histological grade, inducible nitric oxide synthase, matrix metalloproteinase-2, CD-34, Caspase-3, and CD8 in invasive ductal carcinoma of the breast.
Carcinoma, Ductal
Expression of nm23, MMP-2, TIMP-2 in breast neoplasm in Zhengzhou Center Hospital, China.
Carcinoma, Ductal
Expression patterns of stromal MMP-2 and tumoural MMP-2 and -9 are significant prognostic factors in invasive ductal carcinoma of the breast.
Carcinoma, Ductal
Matrix metalloproteinase-2 (MMP-2) and MMP-9 expression in invasive ductal carcinoma of the breast.
Carcinoma, Ductal
Matrix-metalloproteinases 1, 2, and 3 and their tissue inhibitors 1 and 2 in benign and malignant breast lesions: an in situ hybridization study.
Carcinoma, Ductal
RECK expression in pancreatic cancer: its correlation with lower invasiveness and better prognosis.
Carcinoma, Ductal
Seprase, a membrane-bound protease, is overexpressed by invasive ductal carcinoma cells of human breast cancers.
Carcinoma, Ductal
Sequential activation and production of matrix metalloproteinase-2 during breast cancer progression.
Carcinoma, Ductal
Stromal expression of fibroblast activation protein/seprase, a cell membrane serine proteinase and gelatinase, is associated with longer survival in patients with invasive ductal carcinoma of breast.
Carcinoma, Ductal
The interaction between aromatase, metalloproteinase 2,9 and cd44 in breast cancer.
Carcinoma, Embryonal
Increased expression of the matrix metalloproteinase 2 in differentiating Tera 2 human embryonal carcinoma cells.
Carcinoma, Embryonal
Mono-(2-Ethylhexyl) Phthalate (MEHP) Promotes Invasion and Migration of Human Testicular Embryonal Carcinoma Cells.
Carcinoma, Endometrioid
A quantitative evaluation of active gelatinolytic sites in uterine endometrioid adenocarcinoma using film in situ zymography: association of stronger gelatinolysis with myometrial invasion.
Carcinoma, Endometrioid
CD147 (EMMPRIN) and matrix metalloproteinase-2 expression in uterine endometrioid adenocarcinoma.
Carcinoma, Endometrioid
Matrix metalloproteinase-2 and matrix metalloproteinase-9 codistribute with transcription factors RUNX1/AML1 and ETV5/ERM at the invasive front of endometrial and ovarian carcinoma.
Carcinoma, Endometrioid
Matrix metalloproteinases 2 and 9, E-cadherin, and beta-catenin expression in endometriosis, low-grade endometrial carcinoma and non-neoplastic eutopic endometrium.
Carcinoma, Endometrioid
MMP-2, TIMP-1, E-cadherin, and beta-catenin expression in endometrial serous carcinoma compared with low-grade endometrial endometrioid carcinoma and proliferative endometrium.
Carcinoma, Endometrioid
Prognostic significance of matrix metalloproteinases 2 and 9 in endometrial cancer.
Carcinoma, Endometrioid
Prognostic significance of stromal metalloproteinase-2 in ovarian adenocarcinoma and its relation to carcinoma progression.
Carcinoma, Endometrioid
Prognostic value of matrix metalloproteinase-2 (MMP-2) expression in endometrial endometrioid adenocarcinoma.
Carcinoma, Endometrioid
[Expression and significance of Twist1 and MMP-2 in endometrial endometrioid adenocarcinoma].
Carcinoma, Giant Cell
[Inhibitory effect of anti-type IV collagenase intrabody on invasiveness of human pulmonary giant cell carcinoma PG cells in vitro]
Carcinoma, Hepatocellular
(-)-Oleocanthal inhibits growth and metastasis by blocking activation of STAT3 in human hepatocellular carcinoma.
Carcinoma, Hepatocellular
?-mangostin suppresses human hepatocellular carcinoma cell invasion through inhibition of MMP-2 and MMP-9 expression and activating the ERK and JNK pathways.
Carcinoma, Hepatocellular
A synergistic interaction of transcription factors AP2 and YB-1 regulates gelatinase A enhancer-dependent transcription.
Carcinoma, Hepatocellular
Accelerated orthotopic hepatocellular carcinomas growth is linked to increased expression of pro-angiogenic and prometastatic factors in murine liver fibrosis.
Carcinoma, Hepatocellular
Actinidia callosa var. callosa suppresses metastatic potential of human hepatoma cell SK-Hep1 by inhibiting matrix metalloproteinase-2 through PI3K/Akt and MAPK signaling pathways.
Carcinoma, Hepatocellular
An absolute role of the PKC-dependent NF-kappaB activation for induction of MMP-9 in hepatocellular carcinoma cells.
Carcinoma, Hepatocellular
Analysis of matrix metalloproteinase mRNAs expressed in hepatocellular carcinoma cell lines.
Carcinoma, Hepatocellular
Anti-Invasion and Antimetastatic Effects of Porcine Recombinant NK-lysin on SMMC-7721 Human Hepatocellular Carcinoma Cells.
Carcinoma, Hepatocellular
Anti-invasive activity of anthocyanins isolated from Vitis coignetiae in human hepatocarcinoma cells.
Carcinoma, Hepatocellular
Antisense oligonucleotide against clusterin regulates human hepatocellular carcinoma invasion through transcriptional regulation of matrix metalloproteinase-2 and e-cadherin.
Carcinoma, Hepatocellular
Apicidin-resistant HA22T hepatocellular carcinoma cells strongly activated the Wnt/?-catenin signaling pathway and MMP-2 expression via the IGF-IR/PI3K/Akt signaling pathway enhancing cell metastatic effect.
Carcinoma, Hepatocellular
Arsenic trioxide inhibits metastatic potential of mouse hepatoma H22 cells in vitro and in vivo.
Carcinoma, Hepatocellular
Assessment of the clinical significance of serum matrix metalloproteinases MMP-2 and MMP-9 in patients with various chronic liver diseases and hepatocellular carcinoma.
Carcinoma, Hepatocellular
Association of E-cadherin, matrix metalloproteinases, and tissue inhibitors of metalloproteinases with the progression and metastasis of hepatocellular carcinoma.
Carcinoma, Hepatocellular
Autocrine motility factor enhances hepatoma cell invasion across the basement membrane through activation of beta1 integrins.
Carcinoma, Hepatocellular
Bacoside A downregulates matrix metalloproteinases 2 and 9 in DEN-induced hepatocellular carcinoma.
Carcinoma, Hepatocellular
Baicalein Inhibits the Invasion and Metastatic Capabilities of Hepatocellular Carcinoma Cells via Down-Regulation of the ERK Pathway.
Carcinoma, Hepatocellular
Black tea polyphenols target matrix metalloproteinases, RECK, proangiogenic molecules and histone deacetylase in a rat hepatocarcinogenesis model.
Carcinoma, Hepatocellular
Caffeic acid phenethyl ester inhibits invasion and expression of matrix metalloproteinase in SK-Hep1 human hepatocellular carcinoma cells by targeting nuclear factor kappa B.
Carcinoma, Hepatocellular
Caffeoyl pyrrolidine derivative LY52 inhibits hepatocellular carcinoma invasion via suppressing matrix metalloproteinase-2.
Carcinoma, Hepatocellular
CD147, MMP-2, MMP-9 and MVD-CD34 are Significant Predictors of Recurrence After Liver Transplantation in Hepatocellular Carcinoma Patients.
Carcinoma, Hepatocellular
Cellular distribution of 92-kd type IV collagenase/gelatinase B in human hepatocellular carcinoma.
Carcinoma, Hepatocellular
Claudin-1 acts through c-Abl-protein kinase Cdelta (PKCdelta) signaling and has a causal role in the acquisition of invasive capacity in human liver cells.
Carcinoma, Hepatocellular
Clinical and prognostic role of matrix metalloproteinase-2, -9 and their inhibitors in breast cancer and liver diseases: A review.
Carcinoma, Hepatocellular
Clinical usefulness of serum matrix metalloproteinase-2 concentration in patients with chronic viral liver disease.
Carcinoma, Hepatocellular
Clinical value of apoptosis and angiogenesis factors in estimating the prognosis of hepatocellular carcinoma.
Carcinoma, Hepatocellular
Combinatorial interactions of p53, activating protein-2, and YB-1 with a single enhancer element regulate gelatinase A expression in neoplastic cells.
Carcinoma, Hepatocellular
Comparative effects of EGCG, green tea and a nutrient mixture on the patterns of MMP-2 and MMP-9 expression in cancer cell lines.
Carcinoma, Hepatocellular
Correction: liang, j., et Al. Antisense oligonucleotide against clusterin regulates human hepatocellular carcinoma invasion through transcriptional regulation of matrix metalloproteinase-2 and e-cadherin. Int. J. Mol. Sci. 2012, 13, 10594-10607.
Carcinoma, Hepatocellular
CXCL10 accelerates EMT and metastasis by MMP-2 in hepatocellular carcinoma.
Carcinoma, Hepatocellular
Differential expression and origin of membrane-type 1 and 2 matrix metalloproteinases (MT-MMPs) in association with MMP2 activation in injured human livers.
Carcinoma, Hepatocellular
Differential expression of matrix metalloproteinase (MMP)-2, MMP-9, and membrane type 1-MMP in hepatocellular and pancreatic adenocarcinoma: implications for tumor progression and clinical prognosis.
Carcinoma, Hepatocellular
Down-regulation of osteopontin inhibits metastasis of hepatocellular carcinoma cells via a mechanism involving MMP-2 and uPA.
Carcinoma, Hepatocellular
Downregulation of CD147 expression alters cytoskeleton architecture and inhibits gelatinase production and SAPK pathway in human hepatocellular carcinoma cells.
Carcinoma, Hepatocellular
Downregulation of the Notch signaling pathway inhibits hepatocellular carcinoma cell invasion by inactivation of matrix metalloproteinase-2 and -9 and vascular endothelial growth factor.
Carcinoma, Hepatocellular
Earthworm fibrinolytic enzyme: anti-tumor activity on human hepatoma cells in vitro and in vivo.
Carcinoma, Hepatocellular
Effect of all trans-retinoic acid on the secretion of IV collagenase.
Carcinoma, Hepatocellular
Effect of c-myc, Ki-67, MMP-2 and VEGF expression on prognosis of hepatocellular carcinoma patients undergoing tumor resection.
Carcinoma, Hepatocellular
Elevated expression levels of androgen receptors and matrix metalloproteinase-2 and -9 in 30 cases of hepatocellular carcinoma compared with adjacent tissues as predictors of cancer invasion and staging.
Carcinoma, Hepatocellular
Elevated plasma levels of matrix metalloproteinase-9 (92-kd type IV collagenase/gelatinase B) in hepatocellular carcinoma.
Carcinoma, Hepatocellular
Evaluation of anti-invasion effect of resveratrol and related methoxy analogues on human hepatocarcinoma cells.
Carcinoma, Hepatocellular
Evaluation of hepatocellular carcinoma aggressiveness by a panel of extracellular matrix antigens.
Carcinoma, Hepatocellular
Evaluation of serum matrix metalloproteinase (MMP)-9 to MMP-2 ratio as a biomarker in hepatocellular carcinoma.
Carcinoma, Hepatocellular
Exogenous hydrogen sulfide exerts proliferation/anti-apoptosis/angiogenesis/migration effects via amplifying the activation of NF-?B pathway in PLC/PRF/5 hepatoma cells.
Carcinoma, Hepatocellular
Expression of Concern: CD147, MMP-2, MMP-9 and MVD-CD34 are significant predictors of recurrence after liver transplantation in hepatocellular carcinoma patients.
Carcinoma, Hepatocellular
Expression of cytokeratin 19 and matrix metalloproteinase 2 predicts lymph node metastasis in hepatocellular carcinoma.
Carcinoma, Hepatocellular
Expression of LGR8 and related biomarkers in hepatocellular carcinoma: correlation with clinicopathological parameters.
Carcinoma, Hepatocellular
Expression of matrix metalloproiteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) in hepatocellular carcinoma tissue, compared with the surrounding non-tumor tissue.
Carcinoma, Hepatocellular
Expression of the lysyl oxidase propeptide in hepatocellular carcinoma and its clinical relevance.
Carcinoma, Hepatocellular
Expression of vascular endothelial growth factor and matrix metalloproteinase-2 correlates with the invasion and metastasis of hepatocellular carcinoma.
Carcinoma, Hepatocellular
Factors of transforming growth factor beta signalling are co-regulated in human hepatocellular carcinoma.
Carcinoma, Hepatocellular
Full-length soluble CD147 promotes MMP-2 expression and is a potential serological marker in detection of hepatocellular carcinoma.
Carcinoma, Hepatocellular
Functional polymorphisms in the promoters of MMP-1, MMP-2, MMP-3, MMP-9, MMP-12 and MMP-13 are not associated with hepatocellular carcinoma risk.
Carcinoma, Hepatocellular
Gene Expression Profiling of Fixed Tissues Identified Hypoxia-Inducible Factor-1{alpha}, VEGF, and Matrix Metalloproteinase-2 as Biomarkers of Lymph Node Metastasis in Hepatocellular Carcinoma.
Carcinoma, Hepatocellular
Hepatocarcinoma cell lines down-regulate matrix metalloproteinase-2 expression in human hepatic myofibroblasts.
Carcinoma, Hepatocellular
HGF, MET, and matrix-related proteases in hepatocellular carcinoma, fibrolamellar variant, cirrhotic and normal liver.
Carcinoma, Hepatocellular
Human hepatoma cells produce an 85 kDa gelatinase regulated by phorbol 12-myristate 13-acetate.
Carcinoma, Hepatocellular
Immunocytochemical detection of MMP-3 and -10 expression in hepatocellular carcinomas.
Carcinoma, Hepatocellular
In situ detection of matrix metalloproteinase-2 (MMP2) and the metalloproteinase inhibitor TIMP2 transcripts in human primary hepatocellular carcinoma and in liver metastasis.
Carcinoma, Hepatocellular
Increased expression of membrane type 1 matrix metalloproteinase and matrix metalloproteinase-2 with tumor dedifferentiation in hepatocellular carcinomas.
Carcinoma, Hepatocellular
Inhibition of MMP-2 Expression Enhances the Anti-tumor Effect of Sorafenib in Hepatocellular Carcinoma by Suppressing PI3K/AKT/mTOR Pathway.
Carcinoma, Hepatocellular
Inhibitory effect of Daesungki-Tang on the invasiveness potential of hepatocellular carcinoma through inhibition of matrix metalloproteinase-2 and -9 activities.
Carcinoma, Hepatocellular
Inhibitory effect of Sihoga-Yonggol-Moryo-Tang on matrix metalloproteinase-2 and -9 activities and invasiveness potential of hepatocellular carcinoma.
Carcinoma, Hepatocellular
Involvement of PI3K/PTEN/AKT/mTOR pathway in invasion and metastasis in hepatocellular carcinoma: Association with MMP-9.
Carcinoma, Hepatocellular
Knockdown of Golgi phosphoprotein 73 blocks the trafficking of matrix metalloproteinase-2 in hepatocellular carcinoma cells and inhibits cell invasion.
Carcinoma, Hepatocellular
Localization of messenger RNA for tissue inhibitor of metalloproteinases-1 and type IV collagenases/gelatinases in monkey hepatocellular carcinomas.
Carcinoma, Hepatocellular
Matrix Metalloproteinase 2 Knockdown Suppresses the Proliferation of HepG2 and Huh7 Cells and Enhances the Cisplatin Effect.
Carcinoma, Hepatocellular
Messenger RNA expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human hepatocellular carcinoma.
Carcinoma, Hepatocellular
miR-100 Suppresses the Proliferation, Invasion, and Migration of Hepatocellular Carcinoma Cells via Targeting CXCR7.
Carcinoma, Hepatocellular
Morin regulates the expression of NF-kappaB-p65, COX-2 and matrix metalloproteinases in diethylnitrosamine induced rat hepatocellular carcinoma.
Carcinoma, Hepatocellular
No association of MMP-7, MMP-8, and MMP-21 polymorphisms with the risk of hepatocellular carcinoma in a Chinese population.
Carcinoma, Hepatocellular
Osteopontin enhances the expression and activity of MMP-2 via the SDF-1/CXCR4 axis in hepatocellular carcinoma cell lines.
Carcinoma, Hepatocellular
Osteopontin promotes hepatocellular carcinoma invasion by up-regulating MMP-2 and uPA expression.
Carcinoma, Hepatocellular
Overexpression of MT3-MMP in hepatocellular carcinoma correlates with capsular invasion.
Carcinoma, Hepatocellular
Overexpression of Tripartite Motif Conaining 55 (TRIM55) Inhibits Migration and Invasion of Hepatocellular Carcinoma (HCC) Cells via Epithelial-Mesenchymal Transition and Matrix Metalloproteinase-2 (MMP2).
Carcinoma, Hepatocellular
Prognostic values of vascular endothelial growth factor and matrix metalloproteinase-2 in hepatocellular carcinoma after radiotherapy.
Carcinoma, Hepatocellular
Protective effects of fermented rice vinegar sediment (Kurozu moromimatsu) in a diethylnitrosamine-induced hepatocellular carcinoma animal model.
Carcinoma, Hepatocellular
Relation of enhanced secretion of active matrix metalloproteinases with tumor spread in human hepatocellular carcinoma.
Carcinoma, Hepatocellular
Serum levels of tissue inhibitor of metalloproteinases-2 and of precursor form of matrix metalloproteinase-2 in patients with liver disease.
Carcinoma, Hepatocellular
Sinulariolide Suppresses Human Hepatocellular Carcinoma Cell Migration and Invasion by Inhibiting Matrix Metalloproteinase-2/-9 through MAPKs and PI3K/Akt Signaling Pathways.
Carcinoma, Hepatocellular
siRNA suppression of hTERT using activatable cell-penetrating peptides in hepatoma cells.
Carcinoma, Hepatocellular
siRNA targeted against HAb18G/CD147 inhibits MMP-2 secretion, actin and FAK expression in hepatocellular carcinoma cell line via ERK1/2 pathway.
Carcinoma, Hepatocellular
Sonic Hedgehog signaling pathway induces cell migration and invasion through focal adhesion kinase/AKT signaling-mediated activation of matrix metalloproteinase (MMP)-2 and MMP-9 in liver cancer.
Carcinoma, Hepatocellular
The effects of propofol on the growth behavior of hepatoma xenografts in Balb/c mice.
Carcinoma, Hepatocellular
The role of Twist1 in hepatocellular carcinoma angiogenesis: a clinical study.
Carcinoma, Hepatocellular
The Significance of MMP-9 Over MMP-2 in HCC Invasiveness and Recurrence of Hepatocellular Carcinoma After Curative Resection.
Carcinoma, Hepatocellular
Therapeutic effects of tyroserleutide on lung metastasis of human hepatocellular carcinoma SK-HEP-1 and its mechanism affecting ICAM-1 and MMP-2 and -9.
Carcinoma, Hepatocellular
Thyroid hormone regulation of miR-21 enhances migration and invasion of hepatoma.
Carcinoma, Hepatocellular
Up-regulation of TIMP-1 by genipin inhibits MMP-2 activities and suppresses the metastatic potential of human hepatocellular carcinoma.
Carcinoma, Hepatocellular
Upregulation of IL-6 is involved in moderate hyperthermia induced proliferation and invasion of hepatocellular carcinoma cells.
Carcinoma, Hepatocellular
[Antitumor effects of the immunoconjugate composed of lidamycin and monoclonal antibody 3G11]
Carcinoma, Hepatocellular
[Clinical usefulness of plasma activities of gelatinase (matrix metalloproteinase-2 and 9) in chronic liver disease]
Carcinoma, Hepatocellular
[Effects of Biejiajian Pills on Wnt signal pathway signal molecules ?-catenin/TCF4 complex activities and downstream proteins cyclin D1 and MMP-2 in hepatocellular carcinoma cells].
Carcinoma, Hepatocellular
[Expression and clinical impact of vascular endothelial growth factor and matrix metalloproteinase-2 in hepatocellular carcinoma]
Carcinoma, Hepatocellular
[Expression of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases in the hepatocellular carcinomas]
Carcinoma, Hepatocellular
[HBx silencing by shRNA down-regulates MMP-2 expression in human hepatocellular carcinoma cell HepG2.2.15].
Carcinoma, Hepatocellular
[Inhibition of adenovirus-mediated gene transfer of antisense matrix metalloproteinase-2 on hepatocellular carcinoma growth in vivo]
Carcinoma, Hepatocellular
[Recombinant adenovirus vectors carrying antisense matrix metalloproteinase-2 inhibits hepatocellular carcinoma growth in vivo]
Carcinoma, Hepatocellular
[Recombinant adenovirus vectors carrying antisense MMP2 inhibit invasion of HCC cells in vitro]
Carcinoma, Hepatocellular
[Relationship between serum matrix metalloproteinase-2 and metastasis and recurrence following radical hepatic resection in hepatocellular carcinoma]
Carcinoma, Hepatocellular
[Study on effect of arsenic trioxide on adhesion and invasion of human hepatocarcinoma cells in vitro]
Carcinoma, Hepatocellular
[The influence of c-Myc, Ki-67, MMP-2 and VEGF expression on the prognosis of hepatocellular carcinoma patients with tumor resection.]
Carcinoma, Hepatocellular
[The role of MMP-2 in the invasion and metastasis of hepatocellular carcinoma (HCC)]
Carcinoma, Intraductal, Noninfiltrating
Comedo-ductal carcinoma in situ: A paradoxical role for programmed cell death.
Carcinoma, Intraductal, Noninfiltrating
Expression of metalloproteases and their inhibitors by tumor and stromal cells in ductal carcinoma in situ of the breast and their relationship with microinvasive events.
Carcinoma, Intraductal, Noninfiltrating
Expression of nm23, MMP-2, TIMP-2 in breast neoplasm in Zhengzhou Center Hospital, China.
Carcinoma, Intraductal, Noninfiltrating
Sequential activation and production of matrix metalloproteinase-2 during breast cancer progression.
Carcinoma, Intraductal, Noninfiltrating
Serum MMPs and TIMPs: May be predictors of breast carcinogenesis?
Carcinoma, Intraductal, Noninfiltrating
Study of matrix metalloproteinases and their tissue inhibitors in ductal in situ carcinomas of the breast.
Carcinoma, Intraductal, Noninfiltrating
The interaction between aromatase, metalloproteinase 2,9 and cd44 in breast cancer.
Carcinoma, Large Cell
Increased expression of matrix metalloproteinase-2 (MMP-2) predicts tumour recurrence and unfavourable outcome in non-small cell lung cancer.
Carcinoma, Lewis Lung
Combination therapy including a gelatinase inhibitor and cytotoxic agent reduces local invasion and metastasis of murine Lewis lung carcinoma.
Carcinoma, Lewis Lung
Dual regulation of MMP-2 expression by the type 1 insulin-like growth factor receptor: the phosphatidylinositol 3-kinase/Akt and Raf/ERK pathways transmit opposing signals.
Carcinoma, Lewis Lung
Ganoderic acid T inhibits tumor invasion in vitro and in vivo through inhibition of MMP expression.
Carcinoma, Lewis Lung
Inhibition of gelatinase A (MMP-2) by batimastat and captopril reduces tumor growth and lung metastases in mice bearing Lewis lung carcinoma.
Carcinoma, Lewis Lung
Matrix metalloproteinase-9 from bone marrow-derived cells contributes to survival but not growth of tumor cells in the lung microenvironment.
Carcinoma, Lewis Lung
Proteolytic enzymes in tumor metastasis. II. Collagenase type IV activity in subcellular fractions of cloned tumor cell populations.
Carcinoma, Lewis Lung
Reduced angiogenesis and tumor progression in gelatinase A-deficient mice.
Carcinoma, Lobular
Matrix-metalloproteinases 1, 2, and 3 and their tissue inhibitors 1 and 2 in benign and malignant breast lesions: an in situ hybridization study.
Carcinoma, Medullary
Ratio of metalloproteinase 2 to tissue inhibitor of metalloproteinase 2 in medullary thyroid carcinoma.
Carcinoma, Medullary
[Effects of CD147 gene silencing on protein expression of ANXA2,MMP-2 and TIMP-2 by thyroid medullary carcinoma TT cells and biologic characteristics].
Carcinoma, Mucoepidermoid
Comparative Analysis of P63, Maspin and Matrix Metalloproteinase 2 Expression in Mucoepidermoid Carcinoma and Adenoid Cystic Carcinoma of Salivary Glands.
Carcinoma, Mucoepidermoid
Expression of matrix metalloproteinases MMP-2, MMP-9 and their tissue inhibitors TIMP-1, -2, and -3 in benign and malignant tumours of the salivary gland.
Carcinoma, Mucoepidermoid
[Expression of MMP-2 and E-CD in salivary mucoepidermoid carcinoma and its correlation with infiltration, metastasis and prognosis]
Carcinoma, Non-Small-Cell Lung
A third-generation matrix metalloproteinase (MMP) inhibitor (ONO-4817) combined with docetaxel suppresses progression of lung micrometastasis of MMP-expressing tumor cells in nude mice.
Carcinoma, Non-Small-Cell Lung
Association between cyclooxygenase-2 and matrix metalloproteinase-2 expression in non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
Association between expression of activated 72-kilodalton gelatinase and tumor spread in non-small-cell lung carcinoma.
Carcinoma, Non-Small-Cell Lung
Autocrine/paracrine prostaglandin E2 production by non-small cell lung cancer cells regulates matrix metalloproteinase-2 and CD44 in cyclooxygenase-2-dependent invasion.
Carcinoma, Non-Small-Cell Lung
Berberine hydrochloride inhibits cell proliferation and promotes apoptosis of non-small cell lung cancer via the suppression of the MMP2 and Bcl-2/Bax signaling pathways.
Carcinoma, Non-Small-Cell Lung
Biological and clinical significance of MMP-2, MMP-9, TIMP-1 and TIMP-2 in non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
Cancer/Testis Antigens: Expression, Regulation, Tumor Invasion, and Use in Immunotherapy of Cancers.
Carcinoma, Non-Small-Cell Lung
Capn4 promotes non-small cell lung cancer progression via upregulation of matrix metalloproteinase 2.
Carcinoma, Non-Small-Cell Lung
Clinicopathologic significance of ?-catenin and matrix metalloproteinase-2 expression in non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
Degradation of tenascin-C and activity of matrix metalloproteinase-2 are associated with tumor recurrence in early stage non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
Derlin-1 Is Overexpressed in Non-Small Cell Lung Cancer and Promotes Cancer Cell Invasion via EGFR-ERK-Mediated Up-Regulation of MMP-2 and MMP-9.
Carcinoma, Non-Small-Cell Lung
Differential expression of E-cadherin and type IV collagenase genes predicts outcome in patients with stage I non-small cell lung carcinoma.
Carcinoma, Non-Small-Cell Lung
Expression analysis of three miRNAs, miR-26a, miR-29b and miR-519d, in relation to MMP-2 expression level in non-small cell lung cancer patients: a pilot study.
Carcinoma, Non-Small-Cell Lung
Expression of metastasis-associated molecules in non-small cell lung cancer and their prognostic significance.
Carcinoma, Non-Small-Cell Lung
Expression of SHP2 and Related Markers in Non-Small Cell Lung Cancer: A Tissue Microarray Study of 80 Cases.
Carcinoma, Non-Small-Cell Lung
Expression of type IV collagenase correlates with the expression of vascular endothelial growth factor in primary non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
Fibulin-3 promoter methylation alters the invasive behavior of non-small cell lung cancer cell lines via MMP-7 and MMP-2 regulation.
Carcinoma, Non-Small-Cell Lung
GOLPH3 Overexpression is Closely Correlated with Poor Prognosis in Human Non-Small Cell Lung Cancer and Mediates its Metastasis Through Upregulating MMP-2 and MMP-9.
Carcinoma, Non-Small-Cell Lung
ICAM-3 enhances the migratory and invasive potential of human non-small cell lung cancer cells by inducing MMP-2 and MMP-9 via Akt and CREB.
Carcinoma, Non-Small-Cell Lung
IL-17A/IL-17RA promotes invasion and activates MMP-2 and MMP-9 expression via p38 MAPK signaling pathway in non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
Increased expression of matrix metalloproteinase-2 (MMP-2) predicts tumour recurrence and unfavourable outcome in non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
Influence of angiogenetic factors and matrix metalloproteinases upon tumour progression in non-small-cell lung cancer.
Carcinoma, Non-Small-Cell Lung
Influence of MMP-2 and MMP-9 promoter polymorphisms on gene expression and clinical outcome of non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
Inonotus obliquus-derived polysaccharide inhibits the migration and invasion of human non-small cell lung carcinoma cells via suppression of MMP-2 and MMP-9.
Carcinoma, Non-Small-Cell Lung
Matrix metalloproteinase-2 polymorphisms and clinical outcome of Chinese patients with nonsmall cell lung cancer treated with first-line, platinum-based chemotherapy.
Carcinoma, Non-Small-Cell Lung
MED28 and forkhead box M1 (FOXM1) mediate matrix metalloproteinase 2 (MMP2)-dependent cellular migration in human nonsmall cell lung cancer (NSCLC) cells.
Carcinoma, Non-Small-Cell Lung
MicroRNA-130b functions as an oncomiRNA in non-small cell lung cancer by targeting tissue inhibitor of metalloproteinase-2.
Carcinoma, Non-Small-Cell Lung
MicroRNA-29b attenuates non-small cell lung cancer metastasis by targeting matrix metalloproteinase 2 and PTEN.
Carcinoma, Non-Small-Cell Lung
MMP-2, TIMP-2 and CD44v6 Expression in Non-small-cell Lung Carcinomas.
Carcinoma, Non-Small-Cell Lung
Overexpression level of stromelysin 3 is related to the lymph node involvement in non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
Overexpression of matrix metalloproteinase 2 predicts unfavorable outcome in early-stage non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
Prognostic impact of MMP-2 and MMP-9 expression in pathologic stage IA non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
Prognostic significance of overexpressed matrix metalloproteinase-2, mouse-double minute: 2 homolog and epidermal growth factor receptor in non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
Prognostic value of tissue inhibitor of metalloproteinase-2 expression in patients with non-small cell lung cancer: a systematic review and meta-analysis.
Carcinoma, Non-Small-Cell Lung
Progression of non-small cell lung cancer: diagnostic and prognostic utility of matrix metalloproteinase-2, C-reactive protein and serum amyloid A.
Carcinoma, Non-Small-Cell Lung
Recombinant EGFR/MMP-2 bi-targeted fusion protein markedly binding to non-small-cell lung carcinoma and exerting potent therapeutic efficacy.
Carcinoma, Non-Small-Cell Lung
Salinomycin suppresses TGF-?1-induced EMT by down-regulating MMP-2 and MMP-9 via the AMPK/SIRT1 pathway in non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
Serum metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in lung carcinoma patients.
Carcinoma, Non-Small-Cell Lung
The Role of Matrix Metalloproteinase 2 on the Survival of Patients with Non-Small Cell Lung Cancer: A Systematic Review with Meta-Analysis.
Carcinoma, Non-Small-Cell Lung
The VEGFR2, COX-2 and MMP-2 polymorphisms are associated with clinical outcome of patients with inoperable non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
Transfection of nm23-H1 increased expression of beta-Catenin, E-Cadherin and TIMP-1 and decreased the expression of MMP-2, CD44v6 and VEGF and inhibited the metastatic potential of human non-small cell lung cancer cell line L9981.
Carcinoma, Non-Small-Cell Lung
[Effect of Src tyrosine kinase inhibition on secretion of MMP-2 and MMP-9 by non-small cell lung cancer cells].
Carcinoma, Non-Small-Cell Lung
[Expression of MMP-2 and MMP-9 in non-small-cell lung cancer and their prognostic value.]
Carcinoma, Non-Small-Cell Lung
[Prognostic impact of matrix metalloproteinases 2,9, and 11 in stromal cells stage I non-small cell lung cancer]
Carcinoma, Non-Small-Cell Lung
[The expression and its clinical significance of MMP-2 and MMP-9 in non-small cell lung cancer.]
Carcinoma, Ovarian Epithelial
Activated matrix metalloproteinase-2--a potential marker of prognosis for epithelial ovarian cancer.
Carcinoma, Ovarian Epithelial
Expression and correlation of CD44v6, vascular endothelial growth factor, matrix metalloproteinase-2, and matrix metalloproteinase-9 in Krukenberg tumor.
Carcinoma, Ovarian Epithelial
Expression of matrix metalloproteinases-2 and -9 by cells isolated from the peritoneal fluid of women with ovarian carcinoma.
Carcinoma, Ovarian Epithelial
Expression of metalloproteinases MMP-2 and MMP-9 is associated to the presence of androgen receptor in epithelial ovarian tumors.
Carcinoma, Ovarian Epithelial
Expression of MMP-2, -7, -9, MT1-MMP and TIMP-1 and -2 has no prognostic relevance in patients with advanced epithelial ovarian cancer.
Carcinoma, Ovarian Epithelial
Functional role of matrix metalloproteinases in ovarian tumor cell plasticity.
Carcinoma, Ovarian Epithelial
Gelatinase A-immunoreactive protein in ovarian lesions- prognostic value in epithelial ovarian cancer.
Carcinoma, Ovarian Epithelial
Membrane-type matrix metalloproteinase expression and matrix metalloproteinase-2 activation in primary human ovarian epithelial carcinoma cells.
Carcinoma, Ovarian Epithelial
MMP-2 mRNA Expression in Ovarian Cancer Tissues Predicts Patients' Response to Platinum-Taxane Chemotherapy.
Carcinoma, Ovarian Epithelial
Production of extracellular matrix-degrading proteinases by primary cultures of human epithelial ovarian carcinoma cells.
Carcinoma, Ovarian Epithelial
Prognostic Significance of Ets-1 and the Matrix Metalloproteinase-2 to Tissue Inhibitor of Matrix Metalloproteinase-2 Ratio in Egyptian Epithelial Ovarian Cancer Patients.
Carcinoma, Ovarian Epithelial
Prognostic Significance of Extracellular Matrix Metalloproteinase Inducer and Matrix Metalloproteinase 2 in Epithelial Ovarian Cancer.
Carcinoma, Ovarian Epithelial
Prognostic significance of stromal metalloproteinase-2 in ovarian adenocarcinoma and its relation to carcinoma progression.
Carcinoma, Ovarian Epithelial
Prognostic value of MMP-2 for patients with ovarian epithelial carcinoma: a systematic review and meta-analysis.
Carcinoma, Ovarian Epithelial
Stromal-cell derived factor-1 regulates epithelial ovarian cancer cell invasion by activating matrix metalloproteinase-9 and matrix metalloproteinase-2.
Carcinoma, Ovarian Epithelial
The activity of medroxyprogesterone acetate, an androgenic ligand, in ovarian cancer cell invasion.
Carcinoma, Ovarian Epithelial
The correlation between immunohistochemical expression of MMP-2 and the prognosis of epithelial ovarian cancer.
Carcinoma, Ovarian Epithelial
The reinforcement of invasion in epithelial ovarian cancer cells by 17 beta-Estradiol is associated with up-regulation of Snail.
Carcinoma, Ovarian Epithelial
The relevance and role of vascular endothelial growth factor C, matrix metalloproteinase-2 and E-cadherin in epithelial ovarian cancer.
Carcinoma, Ovarian Epithelial
[Association of SNPs in the promoter of MMP-2 and TIMP-2 genes with epithelial ovarian cancer]
Carcinoma, Ovarian Epithelial
[Clinical significance of matrix metalloproteinase-2 expression in patients with epithelial ovarian tumor]
Carcinoma, Ovarian Epithelial
[Elevated expression of matrix metalloproteinase-9, and fibronectin concentration in recurrent epithelial ovarian cancer]
Carcinoma, Pancreatic Ductal
Infrequent stromal expression of gelatinase A and intact basement membrane in intraductal neoplasms of the pancreas.
Carcinoma, Papillary
Expression of matrix metalloproteinase-2 and its tissue inhibitor-2 in fetal and neoplastic thyroid tissue and their significance as diagnostic and prognostic markers in papillary carcinoma.
Carcinoma, Papillary
Increased expression of matrix metalloproteinase-2: a diagnostic marker but not prognostic marker of papillary thyroid carcinoma.
Carcinoma, Papillary
Stromal fibroblasts adjacent to invasive thyroid tumors: expression of gelatinase A but not stromelysin 3 mRNA.
Carcinoma, Papillary
Type IV collagenase and immunostaining of type IV collagen in human thyroid tumors.
Carcinoma, Papillary
[Study of matrix metalloproteinase-2 and -9 in thyroid papillary cancer]
Carcinoma, Renal Cell
A Chinese medicine formula Gegen Qinlian decoction suppresses expansion of human renal carcinoma with inhibition of matrix metalloproteinase-2.
Carcinoma, Renal Cell
Alterations in enhancer of zeste homolog 2, matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 expression are associated with ex vivo and in vitro bone metastasis in renal cell carcinoma.
Carcinoma, Renal Cell
Anticancer effect of lysine, proline, arginine, ascorbic acid and green tea extract on human renal adenocarcinoma line 786-0.
Carcinoma, Renal Cell
Cancer-Specific Survival Stratification Derived from Tumor Expression of Tissue Inhibitor of Metalloproteinase-2 in Non-Metastatic Renal Cell Carcinoma.
Carcinoma, Renal Cell
Clinicopathological significance of matrix metalloproteinase 2 protein expression in patients with renal cell carcinoma: A case-control study and meta-analysis.
Carcinoma, Renal Cell
Clinicopathological Significance of Matrix Metalloproteinase-2 Protein Expression in Renal Cell Carcinoma Patients.
Carcinoma, Renal Cell
Corrigendum: HCRP-1 regulates cell migration and invasion via EGFR-ERK mediated up-regulation of MMP-2 with prognostic significance in human renal cell carcinoma.
Carcinoma, Renal Cell
Effects of a KiSS-1 peptide, a metastasis suppressor gene, on the invasive ability of renal cell carcinoma cells through a modulation of a matrix metalloproteinase 2 expression.
Carcinoma, Renal Cell
Epigallocatechin-3-gallate inhibits migration and invasion of human renal carcinoma cells by downregulating matrix metalloproteinase-2 and matrix metalloproteinase-9.
Carcinoma, Renal Cell
Expression of cyclooxygenase-2 in renal cell carcinoma: correlation with tumor cell proliferation, apoptosis, angiogenesis, expression of matrix metalloproteinase-2, and survival.
Carcinoma, Renal Cell
Expression of metalloproteinase 2 and 9 and their inhibitors in renal cell carcinoma.
Carcinoma, Renal Cell
Expression of nm23-H1 gene product in sarcomatous cancer cells of renal cell carcinoma: correlation with tumor stage and expression of matrix metalloproteinase-2, matrix metalloproteinase-9, sialyl Lewis X, and c-erbB-2.
Carcinoma, Renal Cell
Expression of tissue levels of matrix metalloproteinases and tissue inhibitors of metalloproteinases in renal cell carcinoma.
Carcinoma, Renal Cell
HCRP-1 regulates cell migration and invasion via EGFR-ERK mediated up-regulation of MMP-2 with prognostic significance in human renal cell carcinoma.
Carcinoma, Renal Cell
Histopathological analysis of angiogenic factors in renal cell carcinoma.
Carcinoma, Renal Cell
Imbalance between MMP-2, 9 and TIMP-1 promote the invasion and metastasis of renal cell carcinoma via SKP2 signaling pathways.
Carcinoma, Renal Cell
Influence of cytokines and growth factors on matrix metalloproteinase-2 production and invasion of human renal cancer.
Carcinoma, Renal Cell
Introduction of basic fibroblast growth factor gene into mouse renal cell carcinoma cell line enhances its metastatic potential.
Carcinoma, Renal Cell
Invasive ability of human renal cell carcinoma cell line Caki-2 is accelerated by gamma-aminobutyric acid, via sustained activation of ERK1/2 inducible matrix metalloproteinases.
Carcinoma, Renal Cell
Low concentrations of the recombinant toxin protein rLj-RGD3 suppress TNF-?-induced human renal carcinoma cell invasion.
Carcinoma, Renal Cell
Matrix metallopeptidase 2 (MMP2) mediates MHC class I polypeptide-related sequence A (MICA) shedding in renal cell carcinoma.
Carcinoma, Renal Cell
Matrix metalloproteinase-2 and -9 and tissue inhibitor of metalloproteinase-1 and -2 in sera and urine of patients with renal carcinoma.
Carcinoma, Renal Cell
Matrix metalloproteinase-2 and -9 in the sera and in the urine of human oncocytoma and renal cell carcinoma.
Carcinoma, Renal Cell
Matrix-metalloproteinases and their inhibitors in plasma and tumor tissue of patients with renal cell carcinoma.
Carcinoma, Renal Cell
MicroRNA-132 suppresses migration and invasion of renal carcinoma cells.
Carcinoma, Renal Cell
Modifications of the radiosensitivity of a renal cancer cell line as a consequence of stable TIMP-1 overexpression.
Carcinoma, Renal Cell
Modulation of human renal cell carcinoma 786-0 MMP-2 and MMP-9 activity by inhibitors and inducers in vitro.
Carcinoma, Renal Cell
Monomeric 55-kDa guanidinobenzoatase switches to a serine proteinase activity upon tetramerization. Tetrameric proteinase SP 220 K appears as the native form.
Carcinoma, Renal Cell
mRNA expression of matrix metalloproteases and their inhibitors differs in subtypes of renal cell carcinomas.
Carcinoma, Renal Cell
Neutrophil Gelatinase Associated Lipocalin is an Independent Predictor of Poor Prognosis in Cases of Papillary Renal Cell Carcinoma.
Carcinoma, Renal Cell
Nicotinamide N-methyltransferase Induces Cellular Invasion through Activating Matrix Metalloproteinase-2 Expression in Clear Cell Renal Cell Carcinoma Cells.
Carcinoma, Renal Cell
Osteopontin silencing by small interfering RNA induces apoptosis and suppresses invasion in human renal carcinoma Caki-1 cells.
Carcinoma, Renal Cell
Periostin promotes migration and invasion of renal cell carcinoma through the integrin/focal adhesion kinase/c-Jun N-terminal kinase pathway.
Carcinoma, Renal Cell
PinX1 serves as a potential prognostic indicator for clear cell renal cell carcinoma and inhibits its invasion and metastasis by suppressing MMP-2 via NF-?B-dependent transcription.
Carcinoma, Renal Cell
Progelatinase A mRNA expression in cell lines derived from tumors in patients with metastatic renal cell carcinoma correlates inversely with survival.
Carcinoma, Renal Cell
Regulation of gelatinase production in metastatic renal cell carcinoma by organ-specific fibroblasts.
Carcinoma, Renal Cell
Relative expression of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in mouse renal cell carcinoma cells regulates their metastatic potential.
Carcinoma, Renal Cell
Strong significant correlation between MMP-9 and systemic symptoms in patients with localized renal cell carcinoma.
Carcinoma, Renal Cell
Thymoquinone inhibits metastasis of renal cell carcinoma cell 786-O-SI3 associating with downregulation of MMP-2 and u-PA and suppression of PI3K/Src signaling.
Carcinoma, Renal Cell
XRCC1 serves as a potential prognostic indicator for clear cell renal cell carcinoma and inhibits its invasion and metastasis through suppressing MMP-2 and MMP-9.
Carcinoma, Renal Cell
[mRNA expression analysis of metastatic markers in clear-cell renal cell carcinoma]
Carcinoma, Renal Cell
[Role of organ specific fibroblasts in metastasis of human renal cell carcinoma: regulation of type IV collagenase production from human renal cell carcinoma by organ specific fibroblasts]
Carcinoma, Small Cell
Expression of gelatinase A, tissue inhibitor of metalloproteinases-2, matrilysin, and trypsin(ogen) in lung neoplasms: an immunohistochemical study.
Carcinoma, Small Cell
Immunohistochemical markers of prolonged survival in small cell carcinoma of the lung. An immunohistochemical study.
Carcinoma, Squamous Cell
92-kd gelatinase is actively expressed by eosinophils and stored by neutrophils in squamous cell carcinoma.
Carcinoma, Squamous Cell
A multicenter study on expressions of vascular endothelial growth factor, matrix metallopeptidase-9 and tissue inhibitor of metalloproteinase-2 in oral and maxillofacial squamous cell carcinoma.
Carcinoma, Squamous Cell
Activation of matrix metalloproteinase-2 in head and neck squamous cell carcinoma: studies of clinical samples and in vitro cell lines co-cultured with fibroblasts.
Carcinoma, Squamous Cell
Activation of Wnt5a-Ror2 signaling associated with epithelial-to-mesenchymal transition of tubular epithelial cells during renal fibrosis.
Carcinoma, Squamous Cell
Activity of matrix metalloproteinase-2 (MMP-2) in canine oronasal tumors.
Carcinoma, Squamous Cell
Alpha-mangostin suppresses MMP-2 and MMP-9 expression in head and neck squamous carcinoma cells.
Carcinoma, Squamous Cell
Alteration of MMP-2 and -14 expression by imatinib in HPV-positive and -negative squamous cell carcinoma.
Carcinoma, Squamous Cell
Antimetastatic Effects of Sesamin on Human Head and Neck Squamous Cell Carcinoma through Regulation of Matrix Metalloproteinase-2.
Carcinoma, Squamous Cell
Berberine suppresses in vitro migration and invasion of human SCC-4 tongue squamous cancer cells through the inhibitions of FAK, IKK, NF-kappaB, u-PA and MMP-2 and -9.
Carcinoma, Squamous Cell
Blockage of Squamous Cancer Cell Collective Invasion by FAK Inhibition Is Released by CAFs and MMP-2.
Carcinoma, Squamous Cell
Cancer/Testis Antigens: Expression, Regulation, Tumor Invasion, and Use in Immunotherapy of Cancers.
Carcinoma, Squamous Cell
Clinical significance of expression of membrane type 1 matrix metalloproteinase and matrix metalloproteinase-2 in human head and neck squamous cell carcinoma.
Carcinoma, Squamous Cell
Collagenase-3 expression is associated with advanced local invasion in human squamous cell carcinomas of the larynx.
Carcinoma, Squamous Cell
Correlation of matrix metalloproteinase-2, -9, tissue inhibitor-1 of matrix metalloproteinase and CD44 variant 6 in head and neck cancer metastasis.
Carcinoma, Squamous Cell
Critical roles of Wnt5a-Ror2 signaling in aggressiveness of tongue squamous cell carcinoma and production of matrix metalloproteinase-2 via ?Np63?-mediated epithelial-mesenchymal transition.
Carcinoma, Squamous Cell
Curcumin, a potential inhibitor of MMP-2 in human laryngeal squamous carcinoma cells HEp2.
Carcinoma, Squamous Cell
Cytokine regulation of gelatinase production by head and neck squamous cell carcinoma: the role of tumor necrosis factor-alpha.
Carcinoma, Squamous Cell
Density-dependent induction of 92-kd type IV collagenase activity in cultures of A431 human epidermoid carcinoma cells.
Carcinoma, Squamous Cell
Differential expression and activity status of MMP-1, MMP-2 and MMP-9 in tumor and stromal cells of squamous cell carcinomas of the lung.
Carcinoma, Squamous Cell
Differential expression of matrix metalloproteinase (MMP)-2, MMP-9 and tissue inhibitor of metalloproteinase (TIMP)-1 and TIMP-2 in non-melanoma skin cancer: implications for tumour progression.
Carcinoma, Squamous Cell
Direct cell-cell interaction enhances pro-MMP-2 production and activation in co-culture of laryngeal cancer cells and fibroblasts: involvement of EMMPRIN and MT1-MMP.
Carcinoma, Squamous Cell
EMMPRIN-induced MMP-2 activation cascade in human cervical squamous cell carcinoma.
Carcinoma, Squamous Cell
Enhanced production of matrix metalloproteinase-2 in human head and neck carcinomas is correlated with lymph node metastasis.
Carcinoma, Squamous Cell
Enhancement of membrane-type 1-matrix metalloproteinase (MT1-MMP) production and sequential activation of progelatinase A on human squamous carcinoma cells co-cultured with human dermal fibroblasts.
Carcinoma, Squamous Cell
Epidermal growth factor-like ligands differentially up-regulate matrix metalloproteinase 9 in head and neck squamous carcinoma cells.
Carcinoma, Squamous Cell
Epithelial expression of extracellular matrix metalloproteinase inducer/CD147 and matrix metalloproteinase-2 in neoplasms and precursor lesions derived from cutaneous squamous cells: An immunohistochemical study.
Carcinoma, Squamous Cell
Evaluation of matrix metalloproteinase 2 expression in cervical carcinogenesis using tissue array and integrated optical density for immunoreactivity.
Carcinoma, Squamous Cell
Expression of FLJ10540 is correlated with aggressiveness of oral cavity squamous cell carcinoma by stimulating cell migration and invasion through increased FOXM1 and MMP-2 activity.
Carcinoma, Squamous Cell
Expression of gelatinase A, tissue inhibitor of metalloproteinases-2, matrilysin, and trypsin(ogen) in lung neoplasms: an immunohistochemical study.
Carcinoma, Squamous Cell
Expression of Gelatinases (MMP-2, MMP-9) and Gelatinase Activator (MMP-14) in Actinic Keratosis and in In Situ and Invasive Squamous Cell Carcinoma.
Carcinoma, Squamous Cell
Expression of matrix metalloproteinase-1, -2 and -3 in squamous cell carcinoma and actinic keratosis.
Carcinoma, Squamous Cell
Expression of matrix metalloproteinase-2 (mmp-2) in cervical neoplasia - immunohistochemical and in-situ hybridization studies.
Carcinoma, Squamous Cell
Expression of matrix metalloproteinases and tissue inhibitor of matrix metalloproteinases in non-small-cell lung cancer.
Carcinoma, Squamous Cell
Expression of MMP-2, -9 and -13 in cell lines and fresh biopsies of squamous cell carcinomas of the upper aerodigestive tract.
Carcinoma, Squamous Cell
Expression of tissue inhibitor of matrix metalloproteinase-2 correlates with activation of matrix metalloproteinase-2 and predicts poor prognosis in tongue squamous cell carcinoma.
Carcinoma, Squamous Cell
Expression of type IV collagen, metalloproteinase-2, metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in laryngeal squamous cell carcinomas.
Carcinoma, Squamous Cell
Granulocyte-macrophage colony-stimulating factor upregulates matrix metalloproteinase-2 (MMP-2) and membrane type-1 MMP (MT1-MMP) in human head and neck cancer cells.
Carcinoma, Squamous Cell
Heat shock-mediated transient increase in intracellular 3',5'-cyclic AMP results in tumor specific suppression of membrane type 1-matrix metalloproteinase production and progelatinase A activation.
Carcinoma, Squamous Cell
Immunoelectron microscopic localization of gelatinase A in human gastrointestinal and skin carcinomas: difference between cancer cells and fibroblasts.
Carcinoma, Squamous Cell
Immunoexpression of matrix metalloproteinase-2 and matrix metalloproteinase-9 in the metastasis of squamous cell carcinoma of the human tongue.
Carcinoma, Squamous Cell
Immunohistochemical evaluation of MMP-2, MMP-9 and CD31/microvascular density in squamous cell carcinomas of the floor of the mouth.
Carcinoma, Squamous Cell
Immunohistochemical expression of matrix metalloproteinase-1, matrix metalloproteinase-2 and matrix metalloproteinase-9, myofibroblasts and Ki-67 in actinic cheilitis and lip squamous cell carcinoma.
Carcinoma, Squamous Cell
Immunolocalizations of human gelatinase (type IV collagenase, MMP-9) and TIMP (tissue inhibitor of metalloproteinases) in normal epidermis and some epidermal tumors.
Carcinoma, Squamous Cell
In vivo characterization of activatable cell penetrating peptides for targeting protease activity in cancer.
Carcinoma, Squamous Cell
Increased expression and activation of gelatinolytic matrix metalloproteinases is associated with the progression and recurrence of human cervical cancer.
Carcinoma, Squamous Cell
Increased expression of matrix metalloproteinase-2 in oral cells after short-term stimulation and long-term usage of areca quid.
Carcinoma, Squamous Cell
Increased invasion and matrix metalloproteinase-2 expression by Snail-induced mesenchymal transition in squamous cell carcinomas.
Carcinoma, Squamous Cell
Increased matrix metalloproteinases 2 and 9 and tissue inhibitor of matrix metalloproteinase 2 expression is associated with progression from vulvar intraepithelial neoplasia to invasive carcinoma.
Carcinoma, Squamous Cell
Induction of M(r) 92,000 type IV collagenase expression in a squamous cell carcinoma cell line by fibroblasts.
Carcinoma, Squamous Cell
Inhibition of cervical lymph node metastasis by marimastat (BB-2516) in an orthotopic oral squamous cell carcinoma implantation model.
Carcinoma, Squamous Cell
Inhibitive effect of celecoxib on the adhesion and invasion of human tongue squamous carcinoma cells to extracellular matrix via down regulation of MMP-2 expression.
Carcinoma, Squamous Cell
Involvement of Ets-1 transcription factor in inducing matrix metalloproteinase-2 expression by epithelial-mesenchymal transition in human squamous carcinoma cells.
Carcinoma, Squamous Cell
Involvement of focal adhesion kinase in cellular invasion of head and neck squamous cell carcinomas via regulation of MMP-2 expression.
Carcinoma, Squamous Cell
Laminin-5 gamma2 chain and matrix metalloproteinase-2 expression in the neoplastic changes of uterine cervical squamous epithelium.
Carcinoma, Squamous Cell
Levels of neutrophil gelatinase-assosciated lipocalin in patients with head and neck squamous cell carcinoma in Indian population from Haryana state.
Carcinoma, Squamous Cell
Localization of messenger RNA for Mr 72,000 and 92,000 type IV collagenases in human skin cancers by in situ hybridization.
Carcinoma, Squamous Cell
Localization of the 92 kd gelatinase mRNA in squamous cell and adenocarcinomas of the lung using in situ hybridization.
Carcinoma, Squamous Cell
Matrix metalloproteinase 2 immunoreactive protein appears early in cervical epithelial dedifferentiation.
Carcinoma, Squamous Cell
Matrix metalloproteinase-2 and -14 in p16-positive and -negative HNSCC after exposure To 5-FU and docetaxel In Vitro.
Carcinoma, Squamous Cell
Matrix metalloproteinase-2 expression in laryngeal preneoplastic and neoplastic lesions.
Carcinoma, Squamous Cell
Matrix metalloproteinase-2 status in stromal fibroblasts, not in tumor cells, is a significant prognostic factor in non-small-cell lung cancer.
Carcinoma, Squamous Cell
Matrix metalloproteinase-2, squamous cell carcinoma antigen, and tissue polypeptide-specific antigen expression in Egyptian patients with cervical carcinoma: Relationship with prognosis.
Carcinoma, Squamous Cell
Metalloproteinase-2 expression correlates with aggressiveness of cutaneous squamous cell carcinomas.
Carcinoma, Squamous Cell
MMP-2 and TIMP-2 expression correlates with poor prognosis in cervical carcinoma--a clinicopathologic study using immunohistochemistry and mRNA in situ hybridization.
Carcinoma, Squamous Cell
Modulation of the invasive phenotype of human colon carcinoma cells by organ specific fibroblasts of nude mice.
Carcinoma, Squamous Cell
Newt squamous carcinoma proves phylogenetic conservation of tumors as caricatures of tissue renewal.
Carcinoma, Squamous Cell
Novel 19F activatable probe for the detection of matrix metalloprotease-2 activity by MRI/MRS.
Carcinoma, Squamous Cell
Overexpression of MMP-2 and MMP-9 in squamous cell carcinomas of immunosuppressed patients.
Carcinoma, Squamous Cell
Polysaccharides isolated from Hedyotis diffusa inhibits the aggressive phenotypes of laryngeal squamous carcinoma cells via inhibition of Bcl-2, MMP-2, and ?PA.
Carcinoma, Squamous Cell
Production of matrix metalloproteinase-2 and metalloproteinase-3 related to malignant behavior of esophageal carcinoma. A clinicopathologic study.
Carcinoma, Squamous Cell
Prognostic molecular markers in head and neck squamous cell carcinoma in a New Zealand population: matrix metalloproteinase-2 and sialyl Lewis x antigen.
Carcinoma, Squamous Cell
Prognostic stratification of stage IIIA pN2 non-small cell lung cancer by hierarchical clustering analysis of tissue microarray immunostaining data: an Alpe Adria Thoracic Oncology Multidisciplinary Group study (ATOM 014).
Carcinoma, Squamous Cell
Prognostic value of MMP-2, -9 and TIMP-1,-2 immunoreactive protein at the invasive front in advanced head and neck squamous cell carcinomas.
Carcinoma, Squamous Cell
Protein Expression of MMP-2 and MT1-MMP in Actinic Keratosis, Squamous Cell Carcinoma of the Skin, and Basal Cell Carcinoma.
Carcinoma, Squamous Cell
Role of functional polymorphism of matrix metalloproteinase-2 (-1306 C/T and -168 G/T) and MMP-9 (-1562 C/T) promoter in oral submucous fibrosis and head and neck squamous cell carcinoma in an Indian population.
Carcinoma, Squamous Cell
Role of membrane type 1-matrix metalloproteinase and gelatinase A in head and neck squamous cell carcinoma invasion in vitro.
Carcinoma, Squamous Cell
ROS Production and Distribution: A New Paradigm to Explain the Differential Effects of X-ray and Carbon Ion Irradiation on Cancer Stem Cell Migration and Invasion.
Carcinoma, Squamous Cell
Salivary MMP-1, MMP-2, MMP-3 and MMP-13 Levels in Patients with Oral Lichen Planus and Squamous Cell Carcinoma
Carcinoma, Squamous Cell
Scutellarin inhibits the growth and invasion of human tongue squamous carcinoma through the inhibition of matrix metalloproteinase-2 and -9 and ?v?6 integrin.
Carcinoma, Squamous Cell
Serum levels of matrix metalloproteinase-2 and -9 in patients with head and neck squamous cell carcinoma.
Carcinoma, Squamous Cell
Squamous cell carcinoma growth in mice and in culture is regulated by c-Jun and its control of matrix metalloproteinase-2 and -9 expression.
Carcinoma, Squamous Cell
Stromal cells play a role in cervical cancer progression mediated by MMP-2 protein.
Carcinoma, Squamous Cell
The prognostic value of CXCR4, MMP-2 and MMP-9 in tongue squamous carcinoma.
Carcinoma, Squamous Cell
The prognostic value of the expression of collagenase IV, cathepsin D and metallothionein in squamous cell carcinomas of the skin determined by immunohistochemistry.
Carcinoma, Squamous Cell
The role of matrix metalloproteinases 2 and 9 during rat tongue carcinogenesis induced by 4-nitroquinoline 1-oxide.
Carcinoma, Squamous Cell
The role of MMP-2 and MMP-9 as prognostic markers in the early stages of tongue squamous cell carcinoma.
Carcinoma, Squamous Cell
Therapy of head and neck squamous cell carcinoma with replicative adenovirus expressing tissue inhibitor of metalloproteinase-2 and chemoradiation.
Carcinoma, Squamous Cell
Upregulation of MMP-2 by HMGA1 promotes transformation in undifferentiated, large-cell lung cancer.
Carcinoma, Squamous Cell
[Anti-human collagenase type IV expression in preneoplastic lesions and early squamous cell lung carcinoma]
Carcinoma, Squamous Cell
[Clinicopathological significance of expressions of RECK and MMP-2 in esophageal squamous carcinoma]
Carcinoma, Squamous Cell
[Effect of cyclooxygenase-2 inhibitor on expression of matrix metalloproteinase-2 and invasion of tongue squamous cell carcinoma cell line Tca8113].
Carcinoma, Squamous Cell
[Expression and clinical significance of CD147 and MMP-2 ?in squamous cell carcinoma and adenocarcinoma of the lungs].
Carcinoma, Squamous Cell
[Expression and clinical significance of matrix metalloproteinase-2 in laryngeal squamous cell carcinoma]
Carcinoma, Squamous Cell
[Expression and clinicopathologic significance of OPN, CD44v6 and MMP-2 in squamous cell carcinoma and adenocarcinoma of the lung].
Carcinoma, Squamous Cell
[Expression of matrix metalloproteinase 2 in oral verruvous carcinoma and squamous cell carcinoma]
Carcinoma, Squamous Cell
[Expression of matrix metalloproteinase-2, 9 and their inhibitor-TIMP 1,2 in human squamous cell carcinoma of uterine cervix]
Carcinoma, Squamous Cell
[Expression of MMP-2 and its clinical significance in cervical squamous carcinoma]
Carcinoma, Squamous Cell
[Expression of MMP-2 and MMP-9 in non-small-cell lung cancer and their prognostic value.]
Carcinoma, Squamous Cell
[Matrix metalloproteinase-2 concentrations in squamous cell carcinoma of the head and neck and its clinical significance]
Carcinoma, Squamous Cell
[New direct assay method of type IV collagenase in tissue homogenate and biochemical role of collagenase against type I, and IV collagens to the invasion of the stomach and lung cancer]
Carcinoma, Transitional Cell
Expression of matrix metalloproteinase-2 (MMP-2) and of membrane-type-1-matrix metalloproteinase (MT1-MMP) in transitional cell carcinoma of the upper urinary tract.
Carcinoma, Transitional Cell
Expression of metalloproteinase-2, metalloproteinase-9, and tissue inhibitor of metalloproteinase-1 in transitional cell carcinoma of upper urinary tract: correlation with tumor stage and survival.
Carcinoma, Transitional Cell
Levels of matrix metalloproteases in bladder cancer correlate with tumor grade and invasion.
Carcinoma, Transitional Cell
p38 mitogen-activated protein kinase-driven MAPKAPK2 regulates invasion of bladder cancer by modulation of MMP-2 and MMP-9 activity.
Carcinoma, Transitional Cell
Prognostic value of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in bladder carcinoma.
Carcinoma, Transitional Cell
Role of matrix metalloproteinase-9 in the basement membrane destruction of superficial urothelial carcinomas.
Carcinoma, Transitional Cell
Significance of matrix metalloproteinases and tissue inhibitors of metalloproteinase expression in the recurrence of superficial transitional cell carcinoma of the bladder.
Carcinoma, Transitional Cell
The prognostic value of p53, Ki-67 and matrix metalloproteinases MMP-2 and MMP-9 in transitional cell carcinoma of the renal pelvis and ureter.
Carcinoma, Transitional Cell
Urinary type IV collagenase: elevated levels are associated with bladder transitional cell carcinoma.
Carcinoma, Transitional Cell
[Expressions of MMP-2 and COX-2 mRNA in bladder transitional cell carcinoma and their correlation]
Carcinoma, Transitional Cell
[Significance of activated matrix metalloproteinase 2 (MMP2) in progression of bladder transitional cell carcinoma]
Carcinoma, Verrucous
Immunohistochemical study of p53, Ki-67, MMP-2 and MMP-9 expression at invasive front of squamous cell and verrucous carcinoma in oral cavity.
Carcinosarcoma
The High Mobility Group A1 (HMGA1) gene is highly overexpressed in human uterine serous carcinomas and carcinosarcomas and drives Matrix Metalloproteinase-2 (MMP-2) in a subset of tumors.
Cardiac Output, Low
Latent AKI is
still AKI: the quantification of the burden of renal dysfunction.
Cardiomegaly
Aberrant gene expression of heparanase in ventricular hypertrophy induced by monocrotaline in rats.
Cardiomegaly
Activation of matrix metalloproteinase dilates and decreases cardiac tensile strength.
Cardiomegaly
Crosstalk between obesity and MMP-9 in cardiac remodelling -a cross-sectional study in apparent treatment-resistant hypertension.
Cardiomegaly
Effect of phentolamine on myocardial extracellular matrix of cardiac remodeling in rats.
Cardiomegaly
Effects of pressure overload on extracellular matrix expression in the heart of the atrial natriuretic peptide-null mouse.
Cardiomegaly
Efficacy of nobiletin, a citrus flavonoid, in the treatment of the cardiovascular dysfunction of diabetes in rats.
Cardiomegaly
Hydrogen sulfide mitigates transition from compensatory hypertrophy to heart failure.
Cardiomegaly
Increased Circulating Tissue Inhibitor of Metalloproteinase-2 Is Associated With Resistant Hypertension.
Cardiomegaly
Induction of heparanase gene expression in ventricular myocardium of rats with isoproterenol-induced cardiac hypertrophy.
Cardiomegaly
Investigation of MMP-2 and MMP-9 activities in canine sera with dilated cardiomyopathy.
Cardiomegaly
Matrix Metalloproteinase-2 Mediates a Mechanism of Metabolic Cardioprotection Consisting of Negative Regulation of the Sterol Regulatory Element-Binding Protein-2/3-Hydroxy-3-Methylglutaryl-CoA Reductase Pathway in the Heart.
Cardiomegaly
MMP-2 mediates angiotensin II-induced hypertension under the transcriptional control of MMP-7 and TACE.
Cardiomegaly
Spironolactone prevents alterations associated with cardiac hypertrophy produced by isoproterenol in rats: involvement of SGK-1.
Cardiomegaly
Targeted deletion of matrix metalloproteinase 2 ameliorates myocardial remodeling in mice with chronic pressure overload.
Cardiomegaly
Tumor necrosis factor-alpha-converting enzyme is a key regulator of agonist-induced cardiac hypertrophy and fibrosis.
Cardiomegaly
Verapamil decreases calpain-1 and matrix metalloproteinase-2 activities and improves hypertension-induced hypertrophic cardiac remodeling in rats.
Cardiomyopathies
A functional activating protein 1 (AP-1) site regulates matrix metalloproteinase 2 (MMP-2) transcription by cardiac cells through interactions with JunB-Fra1 and JunB-FosB heterodimers.
Cardiomyopathies
Atrial extracellular matrix remodeling and the maintenance of atrial fibrillation.
Cardiomyopathies
Biomarkers in Trypanosoma cruzi-infected and uninfected individuals with varying severity of cardiomyopathy in Santa Cruz, Bolivia.
Cardiomyopathies
Comparison of levels of matrix metalloproteinase-2 and -3 in patients with ischemic cardiomyopathy versus nonischemic cardiomyopathy.
Cardiomyopathies
Matrix Metalloproteinases MMP-1 and MMP-9 and Their Inhibitor TIMP-1 as Markers of Dilated Cardiomyopathy in Patients of Different Age.
Cardiomyopathies
Reduced degradation of the chemokine MCP-3 by matrix metalloproteinase-2 exacerbates myocardial inflammation in experimental viral cardiomyopathy.
Cardiomyopathies
Role of Matrix Metalloproteinase-2 in the Development of Cyclophosphamide-Induced Cardiomyopathy.
Cardiomyopathies
Selective disruption of MMP-2 gene exacerbates myocardial inflammation and dysfunction in mice with cytokine-induced cardiomyopathy.
Cardiomyopathies
The roles of MMP-2/TIMP-2 in extracellular matrix remodelling in the hearts of STZ-induced diabetic rats.
Cardiomyopathy, Dilated
Comparison of levels of matrix metalloproteinase-2 and -3 in patients with ischemic cardiomyopathy versus nonischemic cardiomyopathy.
Cardiomyopathy, Dilated
Investigation of MMP-2 and MMP-9 activities in canine sera with dilated cardiomyopathy.
Cardiomyopathy, Dilated
Matrix metalloproteinase (MMP)-9, but not MMP-2, is involved in the development and progression of C protein-induced myocarditis and subsequent dilated cardiomyopathy.
Cardiomyopathy, Dilated
Matrix Metalloproteinases MMP-1 and MMP-9 and Their Inhibitor TIMP-1 as Markers of Dilated Cardiomyopathy in Patients of Different Age.
Cardiomyopathy, Dilated
Plasma profiling determinants of matrix homeostasis in paediatric dilated cardiomyopathy.
Cardiomyopathy, Hypertrophic
Increased circulating matrix metalloproteinase-2 in patients with hypertrophic cardiomyopathy with systolic dysfunction.
Cardiomyopathy, Hypertrophic
Left atrial remodelling in hypertrophic cardiomyopathy: relation with exercise capacity and biochemical markers of tissue strain and remodelling.
Cardiomyopathy, Hypertrophic
Procollagen type I carboxy-terminal propeptide (PICP) and MMP-2 are potential biomarkers of myocardial fibrosis in patients with hypertrophic cardiomyopathy.
Cardiotoxicity
Acute doxorubicin-induced cardiotoxicity is associated with matrix metalloproteinase-2 alterations in rats.
Cardiotoxicity
Enhanced gene expression of myocardial matrix metalloproteinases 2 and 9 after acute treatment with doxorubicin in mice.
Cardiotoxicity
Erythropoietin Modulates Imbalance of Matrix Metalloproteinase-2 and Tissue Inhibitor of Metalloproteinase-2 in Doxorubicin-induced Cardiotoxicity.
Cardiotoxicity
MMP inhibitors attenuate doxorubicin cardiotoxicity by preventing intracellular and extracellular matrix remodeling.
Cardiotoxicity
Peroxynitrite-induced myocardial injury is mediated through matrix metalloproteinase-2.
Cardiotoxicity
Ranolazine Attenuates Trastuzumab-Induced Heart Dysfunction by Modulating ROS Production.
Cardiovascular Diseases
Activation of intracellular matrix metalloproteinase-2 by reactive oxygen-nitrogen species: consequences and therapeutic strategies in the heart.
Cardiovascular Diseases
Acute actions and novel targets of matrix metalloproteinases in the heart and vasculature.
Cardiovascular Diseases
Anti-apolipoprotein A-1 IgG predicts major cardiovascular events in patients with rheumatoid arthritis.
Cardiovascular Diseases
Association between plasma neutrophil gelatinase associated lipocalin level and obstructive sleep apnea or nocturnal intermittent hypoxia.
Cardiovascular Diseases
Association of Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9 With Endothelial Dysfunction, Cardiovascular Disease Risk Factors and thrombotic events in Children With End-stage Renal Disease.
Cardiovascular Diseases
Chinese Yellow Wine and Red Wine Inhibit Matrix Metalloproteinase-2 and Improve Atherosclerotic Plaque in LDL Receptor Knockout Mice.
Cardiovascular Diseases
Circulating Matrix Metalloproteinase-2 Is an Independent Correlate of Proteinuria in Patients with Chronic Kidney Disease.
Cardiovascular Diseases
Determinants of circulating matrix metalloproteinase-2 and pregnancy-associated plasma protein-A in patients with chronic kidney disease.
Cardiovascular Diseases
Development of anti-matrix metalloproteinase-2 (MMP-2) nanobodies as potential therapeutic and diagnostic tools.
Cardiovascular Diseases
Effect of Angiotensin II on Matrix Metalloproteinase-2 Secretion in Human Umbilical Vein Endothelial Cells.
Cardiovascular Diseases
Effect of metabolic syndrome risk factors and MMP-2 genetic variations on circulating MMP-2 levels in childhood obesity.
Cardiovascular Diseases
Effects of age on plasma matrix metalloproteinases (MMPs) and tissue inhibitor of metalloproteinases (TIMPs).
Cardiovascular Diseases
Elastin Degradation Is Associated With Progressive Aortic Stiffening and All-Cause Mortality in Predialysis Chronic Kidney Disease.
Cardiovascular Diseases
Elevated concentrations of serum matrix metalloproteinase-2 and -9 and their associations with circulating markers of cardiovascular diseases in chronic arsenic-exposed individuals.
Cardiovascular Diseases
Endogenous nitric oxide formation correlates negatively with circulating matrix metalloproteinase (MMP)-2 and MMP-9 levels in black subjects.
Cardiovascular Diseases
Extrinsic coagulation pathway activation and metalloproteinase-2/TIMPs system are related to oxidative stress and atherosclerosis in hemodialysis patients.
Cardiovascular Diseases
Increase in MMP-2 activity in overweight and obese women is associated with menopausal status.
Cardiovascular Diseases
Increased Matrix Metalloproteinase 2 Activity in the Human Internal Mammary Artery Is Associated with Ageing, Hypertension, Diabetes and Kidney Dysfunction.
Cardiovascular Diseases
Increased plasma activity of metalloproteinase 2 in women with metabolic syndrome.
Cardiovascular Diseases
Is cardiovascular disease in patients with diabetes associated with serum levels of MMP-2, LOX, and the elastin degradation products ELM and ELM-2?
Cardiovascular Diseases
Matrix metalloproteinase 9 polymorphisms and systemic lupus erythematosus: correlation with systemic inflammatory markers and oxidative stress.
Cardiovascular Diseases
Matrix metalloproteinase-2 (MMP-2) gene polymorphism and cardiovascular comorbidity in type 2 diabetes patients.
Cardiovascular Diseases
Matrix metalloproteinase-2 functional promoter polymorphism G1575A is associated with elevated circulatory MMP-2 level and increased risk of cardiovascular disease in systemic lupus erythematosus patients.
Cardiovascular Diseases
Matrix metalloproteinases/tissue inhibitors of metalloproteinases: relationship between changes in proteolytic determinants of matrix composition and structural, functional, and clinical manifestations of hypertensive heart disease.
Cardiovascular Diseases
MiR-29b mimics promotes cell apoptosis of smooth muscle cells via targeting on MMP-2.
Cardiovascular Diseases
MMP-2 mediates angiotensin II-induced hypertension under the transcriptional control of MMP-7 and TACE.
Cardiovascular Diseases
OS 15-02 MATRIX METALLOPROTEINASE 2 KNOCKOUT PROTECTS FROM ANGIOTENSIN II-INDUCED VASCULAR INJURY IN PART VIA INHIBITION OF EGFR AND ERK1/2 ACTIVATION.
Cardiovascular Diseases
Periodontal Condition and Immunological Aspects of Individuals Hospitalized in the Intensive Care Unit.
Cardiovascular Diseases
The Involvement of miR-29b-3p in Arterial Calcification by Targeting Matrix Metalloproteinase-2.
Cardiovascular Diseases
The role of matrix metalloproteinases 2 in atherosclerosis of patients with chronic kidney disease in type 2 diabetes.
Cardiovascular Diseases
The role of neutrophil gelatinase associated lipocalin (NGAL) as biological constituent linking depression and cardiovascular disease.
Cardiovascular Diseases
Two MMP-2 promoter polymorphisms (-790T/G and -735C/T) in chronic heart failure.
Cardiovascular Diseases
Vascular Remodeling and Prothrombotic Markers in Subjects Affected by Familial Combined Hyperlipidemia and/or Metabolic Syndrome in Primary Prevention for Cardiovascular Disease.
Cardiovascular Diseases
Verapamil decreases calpain-1 and matrix metalloproteinase-2 activities and improves hypertension-induced hypertrophic cardiac remodeling in rats.
Carotid Artery Diseases
Genotype association of C(-735)T polymorphism of the MMP-2 gene with the risk of carotid atherosclerosis-vulnerable plaque in the Han Chinese population.
Carotid Artery Diseases
Serum matrix metalloproteinase-2 and increased oxidative stress are associated with carotid atherosclerosis in hemodialyzed patients.
Carotid Artery Diseases
Urokinase-type plasminogen activator and metalloproteinase-2 are independently related to the carotid atherosclerosis in haemodialysis patients.
Carotid Stenosis
Elevated circulating metalloproteinase 7 predicts recurrent cardiovascular events in patients with carotid stenosis: a prospective cohort study.
Carotid Stenosis
Matrix metalloproteinase-2 on activated platelets triggers endothelial PAR-1 initiating atherosclerosis.
Carotid Stenosis
MMP and TIMP alterations in asymptomatic and symptomatic severe recurrent carotid artery stenosis.
Carotid Stenosis
Neutrophil Gelatinase Associated Lipocalin (NGAL) for Identification of Unstable Plaques in Patients with Asymptomatic Carotid Stenosis.
Carotid Stenosis
Neutrophil gelatinase associated lipocalin (NGAL) is elevated in type 2 diabetics with carotid artery stenosis and reduced under metformin treatment.
Carotid Stenosis
Serum values of metalloproteinase-2 and metalloproteinase-9 as related to unstable plaque and inflammatory cells in patients with greater than 70% carotid artery stenosis.
Carpal Tunnel Syndrome
MMP-2 expression is associated with rapidly proliferative arteriosclerosis in the flexor tenosynovium and pain severity in carpal tunnel syndrome.
Cataract
A feasible tool to detect mRNA expression of matrix metalloproteinases and their tissue inhibitors in human Tenon's capsule.
Cataract
Altered expression of transforming growth factor beta 1 and matrix metalloproteinase-9 results in elevated intraocular pressure in mice.
Cataract
Association between MMP-2 gene polymorphism and cataract susceptibility: A protocol for systematic review and meta-analysis.
Cataract
Expression of matrix metalloproteinases of human lens epithelial cells in the cultured lens capsule bag.
Cataract
Gelatinase B/matrix metalloproteinase-9 provokes cataract by cleaving lens betaB1 crystallin.
Cataract
Higher aqueous levels of matrix metalloproteinases indicated visual impairment in patients with retina vein occlusion after anti-VEGF therapy.
Cataract
Higher TGF-?1, TGF-?2, MMP-2 and TIMP-1 Levels in the Aqueous Humor of the Patients with Acute Primary Angle Closure.
Cataract
Human aqueous humor levels of transforming growth factor-?2: Association with matrix metalloproteinases/tissue inhibitors of matrix metalloproteinases.
Cataract
Immunoreactivity of ICAM-1, MMP-2, and Nesfatin-1 in lens epithelial cells of patients with diabetes mellitus with or without diabetic retinopathy.
Cataract
Levels and activation of matrix metalloproteinases in aqueous humor are elevated in uveitis-related secondary glaucoma.
Cataract
Matrix metalloproteinase-2 and -9 activities in the human lens epithelial cells and serum of steroid induced posterior subcapsular cataracts.
Cataract
Matrix metalloproteinases and their inhibitors in aqueous humor of patients with pseudoexfoliation syndrome/glaucoma and primary open-angle glaucoma.
Cataract
MMP-2, MMP-3, TIMP-1, TIMP-2, and TIMP-3 protein levels in human aqueous humor: relationship with axial length.
Cataract
The expression of cytokines in aqueous humor of high myopic patients with cataracts.
Cataract
[Expression and significance of transforming growth factor-beta1, matrix metalloproteinase-2 and its inhibitor in lens epithelial cells of diabetic cataract]
Central Nervous System Diseases
l-Glutamate in Middlebrook 7H9 culture medium upregulates matrix metalloproteinase-2 secretion from human astrocytoma cells.
Cerebral Amyloid Angiopathy
The Interaction of Amyloid ? and the Receptor for Advanced Glycation Endproducts Induces Matrix Metalloproteinase-2 Expression in Brain Endothelial Cells.
Cerebral Hemorrhage
A gelatin in situ-overlay technique localizes brain matrix metalloproteinase activity in experimental focal cerebral ischemia.
Cerebral Hemorrhage
Donor spontaneous intracerebral hemorrhage is associated with systemic activation of matrix metalloproteinase-2 and matrix metalloproteinase-9 and subsequent development of coronary vasculopathy in the heart transplant recipient.
Cerebral Hemorrhage
Early Abrogation of Gelatinase Activity Extends the Time Window for tPA Thrombolysis after Embolic Focal Cerebral Ischemia in Mice.
Cerebral Hemorrhage
Effects of minocycline on apoptosis and angiogenesis-related protein expression in a rat model of intracerebral hemorrhage.
Cerebral Hemorrhage
Exosomes promote restoration after an experimental animal model of intracerebral hemorrhage.
Cerebral Hemorrhage
Ginsenoside Represses Symptomatic Intracerebral Hemorrhage after Recombinant Tissue Plasminogen Activator Therapy by Promoting Transforming Growth Factor-?1.
Cerebral Hemorrhage
Induction of hyperhomocysteinemia models vascular dementia by induction of cerebral microhemorrhages and neuroinflammation.
Cerebral Hemorrhage
Intralesional administration of allogeneic bone marrow stromal cells reduces functional deficits after intracerebral hemorrhage.
Cerebral Hemorrhage
Minocycline reduces spontaneous hemorrhage in mouse models of cerebral amyloid angiopathy.
Cerebral Hemorrhage
Polymorphisms in the Promoters of the MMP-2 and TIMP-2 Genes Are Associated with Spontaneous Deep Intracerebral Hemorrhage in the Taiwan Population.
Cerebral Hemorrhage
Simvastatin improves intracerebral hemorrhage through NF-?B-mediated apoptosis via the MyD88/TRIF signaling pathway.
Cerebral Hemorrhage
Timing of serum active MMP-9 and MMP-2 levels in acute and subacute phases after spontaneous intracerebral hemorrhage.
Cerebral Infarction
Carotid thickness and atherosclerotic plaque stability, serum inflammation, serum MMP-2 and MMP-9 were associated with acute cerebral infarction.
Cerebral Infarction
Correlation between acute myocardial infarction complicated with cerebral infarction and expression levels of MMP-2 and MMP-9.
Cerebral Infarction
Neuroprotection by platelet-activating factor acetylhydrolase in a mouse model of transient cerebral ischemia.
Cerebral Infarction
The serum levels of MMP-9, MMP-2 and vWF in patients with low doses of urokinase peritoneal dialysis decreased uremia complicated with cerebral infarction.
Cerebral Infarction
White matter damage is associated with matrix metalloproteinases in vascular dementia.
Cerebrovascular Disorders
Effect of dietary ? carotene on cerebral aneurysm and subarachnoid haemorrhage in the brain apo E(-/-) mice.
Cerebrovascular Disorders
Increased Levels of Soluble Cluster of Differentiation 40 Ligand, Matrix Metalloproteinase 9, and Matrix Metalloproteinase 2 Are Associated with Carotid Plaque Vulnerability in Patients with Ischemic Cerebrovascular Disease.
Cervical Intraepithelial Neoplasia
A coumarin-based fluorescence resonance energy transfer probe targeting matrix metalloproteinase-2 for the detection of cervical cancer.
Cervical Intraepithelial Neoplasia
Comparative study of MMP-2 (matrix metalloproteinase 2) immune expression in normal uterine cervix, intraepithelial neoplasias, and squamous cells cervical carcinoma.
Cervical Intraepithelial Neoplasia
Early acquisition of gelatinolytic activity in carcinogenesis of the uterine cervix.
Cervical Intraepithelial Neoplasia
Evaluation of matrix metalloproteinase 2 expression in cervical carcinogenesis using tissue array and integrated optical density for immunoreactivity.
Cervical Intraepithelial Neoplasia
Expression of matrix metalloproteinase-2 and 9 in cervical intraepithelial neoplasia and cervical carcinoma among different age groups of premenopausal and postmenopausal women.
Cervical Intraepithelial Neoplasia
Expression of MMP-2, MMP-9, and urokinase-type plasminogen activator in cervical intraepithelial neoplasia.
Cervical Intraepithelial Neoplasia
MMP-2 and TIMP-2 expression correlates with poor prognosis in cervical carcinoma--a clinicopathologic study using immunohistochemistry and mRNA in situ hybridization.
Cervical Intraepithelial Neoplasia
Predicting high-risk human papillomavirus infection, progression of cervical intraepithelial neoplasia, and prognosis of cervical cancer with a panel of 13 biomarkers tested in multivariate modeling.
Cervical Intraepithelial Neoplasia
Stromal cells play a role in cervical cancer progression mediated by MMP-2 protein.
Chagas Cardiomyopathy
Biomarkers in Trypanosoma cruzi-infected and uninfected individuals with varying severity of cardiomyopathy in Santa Cruz, Bolivia.
Chagas Cardiomyopathy
Synergic and antagonistic relationship between MMP-2 and MMP-9 with fibrosis and inflammation in Chagas' cardiomyopathy.
Chagas Disease
Differential Expression of Matrix Metalloproteinases 2, 9 and Cytokines by Neutrophils and Monocytes in the Clinical Forms of Chagas Disease.
Chagas Disease
Matrix metalloproteinases 2 and 9 are differentially expressed in patients with indeterminate and cardiac clinical forms of chagas disease.
Chagas Disease
MMP-2 and MMP-9 plasma levels are potential biomarkers for indeterminate and cardiac clinical forms progression in chronic Chagas disease.
Chagas Disease
Sialic acid removal by trans-sialidase modulates MMP-2 activity during Trypanosoma cruzi infection.
Chagas Disease
Synergic and antagonistic relationship between MMP-2 and MMP-9 with fibrosis and inflammation in Chagas' cardiomyopathy.
Chediak-Higashi Syndrome
Giant granules of neutrophils in Chediak-Higashi syndrome are derived from azurophil granules but not from specific and gelatinase granules.
Cheilitis
Immunohistochemical expression of matrix metalloproteinase-1, matrix metalloproteinase-2 and matrix metalloproteinase-9, myofibroblasts and Ki-67 in actinic cheilitis and lip squamous cell carcinoma.
Cholangiocarcinoma
Ductular reaction after submassive necrosis in humans. Special emphasis on analysis of ductular hepatocytes.
Cholangiocarcinoma
Expression of epidermal growth factor receptor, apomucins, matrix metalloproteinases, and p53 in rat and human cholangiocarcinoma: appraisal of an animal model of cholangiocarcinoma.
Cholangiocarcinoma
Expression of Matrix Metalloproteinase 2 and Extracellular Matrix Metalloproteinase Inducer are Unfavorable Postoperative Prognostic Factors in Intrahepatic Cholangiocarcinoma.
Cholangiocarcinoma
Expression of matrix metalloproteinase 7 is an unfavorable postoperative prognostic factor in cholangiocarcinoma of the perihilar, hilar, and extrahepatic bile ducts.
Cholangiocarcinoma
Expression of matrix metalloproteinase-2 and -9 and tissue inhibitor of metalloproteinase-1 and -2 in intraductal and nonintraductal growth type of cholangiocarcinoma.
Cholangiocarcinoma
Inhibitory effect of isomorellin on cholangiocarcinoma cells via suppression of NF-?B translocation, the phosphorylated p38 MAPK pathway and MMP-2 and uPA expression.
Cholangiocarcinoma
Rhinacanthin-C Extracted from Rhinacanthus nasutus (L.) Inhibits Cholangiocarcinoma Cell Migration and Invasion by Decreasing MMP-2, uPA, FAK and MAPK Pathways
Cholangiocarcinoma
The expression of matrix metalloproteinases in intrahepatic cholangiocarcinoma, hilar (Klatskin tumor), middle and distal extrahepatic cholangiocarcinoma, gallbladder cancer, and ampullary carcinoma: role of matrix metalloproteinases in tumor progression and prognosis.
Cholangiocarcinoma
TPX2 level correlates with cholangiocarcinoma cell proliferation, apoptosis, and EMT.
Cholangiocarcinoma
Wip1 is associated with tumorigenity and metastasis through MMP-2 in human intrahepatic cholangiocarcinoma.
Cholangitis, Sclerosing
MMP-2 is a disease-modifying gene in primary sclerosing cholangitis.
Cholecystitis
Expression of matrix metalloproteinases in gallbladder carcinoma and their significance in carcinogenesis.
Cholecystitis
Prediction of prognosis in gallbladder carcinoma by CD147 and MMP-2 immunohistochemistry.
Cholera
Elevated cyclic AMP suppresses ConA-induced MT1-MMP expression in MDA-MB-231 human breast cancer cells.
Cholera
Pituitary adenylate cyclase-activating polypeptide acts synergistically with relaxin in modulating ovarian cell function in rats.
Cholestasis
Cholestatic liver fibrosis and toxin-induced fibrosis are exacerbated in matrix metalloproteinase-2 deficient mice.
Cholestasis
Increased MMP-7 expression in biliary epithelium and serum underpins native liver fibrosis after successful portoenterostomy in biliary atresia.
Cholestasis
Lobe-specific heterogeneity in asymmetric dimethylarginine and matrix metalloproteinase levels in a rat model of obstructive cholestasis.
Cholestasis
Opioid system blockade decreases collagenase activity and improves liver injury in a rat model of cholestasis.
Cholestasis, Intrahepatic
Epigallocatechin-3-gallate ameliorates intrahepatic cholestasis of pregnancy by inhibiting matrix metalloproteinase-2 and matrix metalloproteinase-9.
Cholestasis, Intrahepatic
Identification of Matrix Metalloproteinase-2 and 9 as Biomarker of Intrahepatic Cholestasis of Pregnancy.
Cholesteatoma
Association of Matrix Metalloproteinase-2 mRNA Expression with Subtypes of Pediatric Cholesteatoma.
Cholesteatoma
Effect of CT manifestations of cholesteatoma on MMP-2, MMP-9 and IL-6 in the serum of patients.
Cholesteatoma
Evaluation of significant gene expression changes in congenital and acquired cholesteatoma.
Cholesteatoma
Expression of matrix-metalloproteinases and their inhibitors in human cholesteatomas.
Cholesteatoma
Gelatinolytic activity of matrix metalloproteinases 2 and 9 in middle ear cholesteatoma.
Cholesteatoma
Matrix metalloproteinase-1 in cholesteatoma, middle ear granulations and deep meatal skin: a comparative analysis.
Cholesteatoma
Matrix metalloproteinase-2 and matrix metalloproteinase-9 in cholesteatoma and deep meatal skin.
Cholesteatoma
Modeling the cholesteatoma microenvironment: coculture of HaCaT keratinocytes with WS1 fibroblasts induces MMP-2 activation, invasive phenotype, and proteolysis of the extracellular matrix.
Cholesteatoma
TREM-2 promotes acquired cholesteatoma-induced bone destruction by modulating TLR4 signaling pathway and osteoclasts activation.
Cholesteatoma
Up-regulation of matrix metalloprotease-9 in middle ear cholesteatoma--correlations with growth factor expression in vivo?
Cholesteatoma
[Expression of matrix metalloproteinasa-2,9 in cholesteatoma and middle ear cancer]
Cholesteatoma
[Expression of matrix metalloproteinase-2,9 in cholesteatoma from different positions]
Choline Deficiency
Immunohistochemical determination of the extracellular matrix modulation in a rat model of choline-deprived myocardium: the effects of carnitine.
Chondroma
Expression of membrane type 1 matrix metalloproteinase, matrix metalloproteinase 2 and tissue inhibitor of metalloproteinase 2 in human cartilaginous tumors with special emphasis on mesenchymal and dedifferentiated chondrosarcoma.
Chondrosarcoma
Alendronate inhibits cell invasion and MMP-2 secretion in human chondrosarcoma cell line.
Chondrosarcoma
AMP-activated protein kinase activation mediates CCL3-induced cell migration and matrix metalloproteinase-2 expression in human chondrosarcoma.
Chondrosarcoma
Anti-tumor effects of a nonsteroidal anti-inflammatory drug zaltoprofen on chondrosarcoma via activating peroxisome proliferator-activated receptor gamma and suppressing matrix metalloproteinase-2 expression.
Chondrosarcoma
Correlation between the histological grade of chondrosarcoma and the expression of MMPs, ADAMTSs and TIMPs.
Chondrosarcoma
Correlation of hypoxic signalling to histological grade and outcome in cartilage tumours.
Chondrosarcoma
Expression of matrix metalloproteinases 1, 2, 9 and their tissue inhibitor-1 in cartilage-forming osteal tumors.
Chondrosarcoma
Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human chondrosarcomas.
Chondrosarcoma
Expression of membrane type 1 matrix metalloproteinase, matrix metalloproteinase 2 and tissue inhibitor of metalloproteinase 2 in human cartilaginous tumors with special emphasis on mesenchymal and dedifferentiated chondrosarcoma.
Chondrosarcoma
In vitro modulation of MMP-2 and MMP-9 in adult human sarcoma cell lines by cytokines, inducers and inhibitors.
Chondrosarcoma
Modulation of u-PA, MMPs and their inhibitors by a novel nutrient mixture in adult human sarcoma cell lines.
Chondrosarcoma
Production of matrix metalloproteinases and a metalloproteinase inhibitor by swarm rat chondrosarcoma.
Chondrosarcoma
Resistin promotes tumor metastasis by down-regulation of miR-519d through the AMPK/p38 signaling pathway in human chondrosarcoma cells.
Chondrosarcoma
Resveratrol attenuates matrix metalloproteinase-9 and -2-regulated differentiation of HTB94 chondrosarcoma cells through the p38 kinase and JNK pathways.
Chondrosarcoma
Sphingosine-1-phosphate suppresses chondrosarcoma metastasis by upregulation of tissue inhibitor of metalloproteinase 3 through suppressing miR-101 expression.
Chondrosarcoma
The mir-423-5p/MMP-2 Axis Regulates the Nerve Growth Factor-Induced Promotion of Chondrosarcoma Metastasis.
Chondrosarcoma
Thrombin enhanced migration and MMPs expression of human chondrosarcoma cells involves PAR receptor signaling pathway.
Chondrosarcoma
Visfatin Promotes the Metastatic Potential of Chondrosarcoma Cells by Stimulating AP-1-Dependent MMP-2 Production in the MAPK Pathway.
Chondrosarcoma
WISP-1 increases MMP-2 expression and cell motility in human chondrosarcoma cells.
Chondrosarcoma, Mesenchymal
Expression of membrane type 1 matrix metalloproteinase, matrix metalloproteinase 2 and tissue inhibitor of metalloproteinase 2 in human cartilaginous tumors with special emphasis on mesenchymal and dedifferentiated chondrosarcoma.
Chordoma
Expression of hypoxia-inducible factor-1?, vascular endothelial growth factor and matrix metalloproteinase-2 in sacral chordomas.
Chordoma
Expression of matrix metalloproteinase (MMP)-1, MMP-2, MMP-9, cathepsin B, and urokinase plasminogen activator in non-skull base chordoma.
Chorioamnionitis
Chorioamnionitis and increased neonatal lung lavage fluid matrix metalloproteinase-9 levels: implications for antenatal origins of chronic lung disease.
Chorioamnionitis
Low maternal serum matrix metalloproteinase (MMP)-2 concentrations are associated with preterm labor and fetal inflammatory response.
Chorioamnionitis
Maternal Betamethasone and Chorioamnionitis Induce Different Collagenases during Lung Maturation in Fetal Sheep.
Chorioamnionitis
Premature rupture of the fetal membrane combined with subclinical chorioamnionitis negatively affects pregnancy outcomes by a mechanism associated with reduced levels of matrix metalloproteinase-2.
Chorioamnionitis
Protease production by microorganisms associated with reproductive tract infection.
Choriocarcinoma
Cloning of choriocarcinoma cells shows that invasion correlates with expression and activation of gelatinase A.
Choriocarcinoma
Expression and importance of matrix metalloproteinase 2 and 9 (MMP-2 and -9) in human trophoblast invasion.
Choriocarcinoma
HSPC117 is regulated by epigenetic modification and is involved in the migration of JEG-3 cells.
Choriocarcinoma
Low-molecular weight heparin induces in vitro trophoblast invasiveness: role of matrix metalloproteinases and tissue inhibitors.
Choriocarcinoma
Matrix metalloproteinases and their inhibitors in gestational trophoblastic diseases and normal placenta.
Choriocarcinoma
Mechanisms of matrix metalloproteinase-2 (mmp-2) transcriptional repression by progesterone in jar choriocarcinoma cells.
Choriocarcinoma
p53 Mediates Epidermal Growth Factor (EGF) Induction of MMP-2 Transcription and Trophoblast Invasion.
Choriocarcinoma
Reduced expression of tissue inhibitor of metalloproteinase (TIMP)-2 in gestational trophoblastic diseases.
Choriocarcinoma
Resistance of malignant trophoblast cells to both the anti-proliferative and anti-invasive effects of transforming growth factor-beta.
Choriocarcinoma
Resistin regulates human choriocarcinoma cell invasive behaviour and endothelial cell angiogenic processes.
Choriocarcinoma
Suppression of choriocarcinoma invasion and metastasis following blockade of BDNF/TrkB signaling.
Choriocarcinoma
Suppression of gelatinase production with decreased invasiveness of choriocarcinoma cells by human recombinant interferon beta.
Choriocarcinoma
[Regulation of matrix-degrading enzymes in gynecologic cancer tissues and cells]
Choroidal Neovascularization
Matrix metalloproteinase (MMP) expression in experimental choroidal neovascularization.
Choroidal Neovascularization
MMP-2 and MMP-9 synergize in promoting choroidal neovascularization.
Choroidal Neovascularization
The non-antibiotic properties of tetracyclines: Clinical potential in ophthalmic disease.
Chromoblastomycosis
Secretion of five extracellular enzymes by strains of chromoblastomycosis agents.
Chronic Periodontitis
Activation of human matrix metalloproteinase 2 by gingival crevicular fluid and Porphyromonas gingivalis.
Chronic Periodontitis
Activation of MMP-2 by Porphyromonas gingivalis in human periodontal ligament cells.
Chronic Periodontitis
Analysis of in situ protease activity in chronic adult periodontitis patients: expression of activated MMP-2 and a 40 kDa serine protease.
Chronic Periodontitis
Diabetes may affect the expression of matrix metalloproteinases and their inhibitors more than smoking in chronic periodontitis.
Chronic Periodontitis
Effect of Azadirachta indica (Neem) and Aloe vera as compared to subantimicrobial dose doxycycline on matrix metalloproteinases (MMP)-2 and MMP-9: An in-vitro study.
Chronic Periodontitis
Effects of therapy with two combinations of antibiotics on the imbalance of MMP-2÷TIMP-2 in chronic periodontitis.
Chronic Periodontitis
Expression of matrix metalloproteinases-2, -9 and reversion-inducing cysteine-rich protein with Kazal motifs in gingiva in periodontal health and disease.
Chronic Periodontitis
Expression of metalloproteinases and their tissue inhibitors in inflamed gingival biopsies.
Chronic Periodontitis
Gene polymorphisms of matrix metalloproteinase-2, -9 and -12 in periodontal health and severe chronic periodontitis.
Chronic Periodontitis
Genetic variations in the human gelatinase A (matrix metalloproteinase-2) promoter are not associated with susceptibility to, and severity of, chronic periodontitis.
Chronic Periodontitis
Increased expression of extracellular matrix metalloproteinase inducer is associated with matrix metalloproteinase-1 and -2 in gingival tissues from patients with periodontitis.
Chronic Periodontitis
Inhibitory effect of procyanidin oligomer from elm cortex on the matrix metalloproteinases and proteases of periodontopathogens.
Chronic Periodontitis
Interaction between the Wnt/?-catenin signaling pathway and the EMMPRIN/MMP-2, 9 route in periodontitis.
Chronic Periodontitis
Matrix metalloproteinase-2, -9, and tissue inhibitor of MMP-2 gene polymorphisms in Taiwanese periodontitis patients.
Chronic Periodontitis
Multiple forms of gelatinases/type IV collagenases in saliva and gingival crevicular fluid of periodontitis patients.
Chronic Periodontitis
The expressions of inflammatory factors and tissue inhibitor of matrix metalloproteinase-2 in human chronic periodontitis with type 2 diabetes mellitus.
Chronic Periodontitis
[Expression of MMP-2 and MMP-3 in periodontal tissues of rat periodontitis model]
Churg-Strauss Syndrome
Modulation of MMP-2 and MMP-9 in Churg-Strauss syndrome respiratory mucosa: potential monitoring parameters.
Cleft Lip
Evaluation of the presence of MMP-2, TIMP-2, BMP2/4, and TGF?3 in the facial tissue of children with cleft lip and palate.
Coinfection
Active form of gelatinases in tear fluidin patients with corneal ulcer or ocular burn.
Coinfection
Helminth Coinfection Is Associated With Enhanced Plasma Levels of Matrix Metalloproteinases and Tissue Inhibitor of Metalloproteinases in Tuberculous Lymphadenitis.
Coinfection
Levels of Serum Markers of Liver Inflammation and Fibrosis in Patients with Chronic Hepatitis C Virus Infection According to HIV Status and Antiretroviral Use.
Coinfection
Matrix metalloproteases and their tissue inhibitors in non-alcoholic liver fibrosis of human immunodeficiency virus-infected patients.
Colic
Detecting early kidney damage in horses with colic by measuring matrix metalloproteinase -9 and -2, other enzymes, urinary glucose and total proteins.
Colitis
Attenuation of dextran sodium sulphate induced colitis in matrix metalloproteinase-9 deficient mice.
Colitis
Comparisons of gut microbiota profiles in wild-type and gelatinase B/matrix metalloproteinase-9-deficient mice in acute DSS-induced colitis.
Colitis
Dyospiros kaki phenolics inhibit colitis and colon cancer cell proliferation, but not gelatinase activities.
Colitis
Enterococcus faecalis Metalloprotease Compromises Epithelial Barrier and Contributes to Intestinal Inflammation.
Colitis
Genetic Deletion of Tissue Inhibitor of Metalloproteinase-1/TIMP-1 Alters Inflammation and Attenuates Fibrosis in Dextran Sodium Sulphate-induced Murine Models of Colitis.
Colitis
Increased activity and expression of matrix metalloproteinase-9 in a rat model of distal colitis.
Colitis
Inhibition of gelatinase B/MMP-9 does not attenuate colitis in murine models of inflammatory bowel disease.
Colitis
Matrix metalloproteinase-9 and metalloproteinase-2 activity and expression is reduced by melatonin during experimental colitis.
Colitis
Matrix metalloproteinase-9 modulates intestinal injury in rats with transmural colitis.
Colitis
Matrix metalloproteinase-9-mediated tissue injury overrides the protective effect of matrix metalloproteinase-2 during colitis.
Colitis
Pterostilbene Attenuates High-Fat Diet and Dextran Sulfate Sodium-Induced Colitis via Suppressing Inflammation and Intestinal Fibrosis in Mice.
Colitis
Selective ablation of matrix metalloproteinase-2 exacerbates experimental colitis: contrasting role of gelatinases in the pathogenesis of colitis.
Colitis
Selective gelatinase inhibition reduces apoptosis and pro-inflammatory immune cell responses in Campylobacter jejuni-infected gnotobiotic IL-10 deficient mice.
Colitis
Targeted deletion of metalloproteinase 9 attenuates experimental colitis in mice: central role of epithelial-derived MMP.
Colitis, Ulcerative
Accuracy of Faecal Calprotectin and Neutrophil Gelatinase B-associated Lipocalin in Evaluating Subclinical Inflammation in UlceRaTIVE Colitis-the ACERTIVE study.
Colitis, Ulcerative
Auraptene decreases the activity of matrix metalloproteinases in dextran sulfate sodium-induced ulcerative colitis in ICR mice.
Colitis, Ulcerative
Changes in MMP-2, MMP-9, inflammation, blood coagulation and intestinal mucosal permeability in patients with active ulcerative colitis.
Colitis, Ulcerative
Effect of Etiasa on the expression of matrix metalloproteinase-2 and tumor necrosis factor-? in a rat model of ulcerative colitis.
Colitis, Ulcerative
Enhanced expression of MMP-7 and MMP-13 in inflammatory bowel disease: a precancerous potential?
Colitis, Ulcerative
Expression and regulation of tissue inhibitor of metalloproteinase-1 and matrix metalloproteinases by intestinal myofibroblasts in inflammatory bowel disease.
Colitis, Ulcerative
Expressions of Matrix Metalloproteinases (MMP-2, MMP-7, and MMP-9) and Their Inhibitors (TIMP-1, TIMP-2) in Inflammatory Bowel Diseases.
Colitis, Ulcerative
Increased incidence of urinary matrix metalloproteinases as predictors of disease in pediatric patients with inflammatory bowel disease.
Colitis, Ulcerative
Neutrophil gelatinase B-associated lipocalin and matrix metalloproteinase-9 complex as a surrogate serum marker of mucosal healing in ulcerative colitis.
Colonic Neoplasms
A key role of microRNA-29b for the suppression of colon cancer cell migration by American ginseng.
Colonic Neoplasms
Anti-beta4 integrin antibodies enhance migratory and invasive abilities of human colon adenocarcinoma cells and their MMP-2 expression.
Colonic Neoplasms
Balance between activation and inhibition of matrix metalloproteinase-2 (MMP-2) is altered in colorectal tumors compared to normal colonic epithelium.
Colonic Neoplasms
CD155 knockdown promotes apoptosis via AKT/Bcl-2/Bax in colon cancer cells.
Colonic Neoplasms
Characterization of a profile of the anthocyanins isolated from Vitis coignetiae Pulliat and their anti-invasive activity on HT-29 human colon cancer cells.
Colonic Neoplasms
Colon cancer cell-derived tumor necrosis factor-alpha mediates the tumor growth-promoting response in macrophages by up-regulating the colony-stimulating factor-1 pathway.
Colonic Neoplasms
Colony-stimulating factor-1 antisense treatment suppresses growth of human tumor xenografts in mice.
Colonic Neoplasms
Construction of a recombinant eukaryotic expression vector containing DNM3 gene and its expression in colon cancer cells.
Colonic Neoplasms
Conversion of highly malignant colon cancer from an aggressive to a controlled disease by oral administration of a metalloproteinase inhibitor.
Colonic Neoplasms
Curcumin inhibits cell migration of human colon cancer colo 205 cells through the inhibition of nuclear factor kappa B /p65 and down-regulates cyclooxygenase-2 and matrix metalloproteinase-2 expressions.
Colonic Neoplasms
Diallyl sulfide, diallyl disulfide, and diallyl trisulfide inhibit migration and invasion in human colon cancer colo 205 cells through the inhibition of matrix metalloproteinase-2, -7, and -9 expressions.
Colonic Neoplasms
Differential inhibition of gelatinase activity in human colon adenocarcinoma cells by Aloe vera and Aloe arborescens extracts.
Colonic Neoplasms
Dyospiros kaki phenolics inhibit colitis and colon cancer cell proliferation, but not gelatinase activities.
Colonic Neoplasms
Endocrine gland-derived vascular endothelial growth factor strengthens cell invasion ability via prokineticin receptor 2 in colon cancer cell lines.
Colonic Neoplasms
Evaluation of the expression of metalloproteinases 2 and 9 and their tissue inhibitors in colon cancer cells treated with phytic acid.
Colonic Neoplasms
Evidence for tumor-host cooperation in regulating MMP-2 expression in human colon cancer.
Colonic Neoplasms
Extracellular vesicles carrying miR-193a derived from mesenchymal stem cells impede cell proliferation, migration and invasion of colon cancer by downregulating FAK.
Colonic Neoplasms
FABP4 promotes invasion and metastasis of colon cancer by regulating fatty acid transport.
Colonic Neoplasms
Glucose regulated protein 78 promotes cell invasion via regulation of uPA production and secretion in colon cancer cells.
Colonic Neoplasms
Heated and humidified CO2 pneumoperitoneum inhibits tumour cell proliferation, migration and invasion in colon cancer.
Colonic Neoplasms
Host CD147 blockade by small interfering RNAs suppresses growth of human colon cancer xenografts.
Colonic Neoplasms
Host expression of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in normal colon tissue affects metastatic potential of colorectal cancer.
Colonic Neoplasms
Immunohistochemically detected high expression of matrix metalloproteinase-2 as predictor of poor prognosis in Duke's B colon cancer.
Colonic Neoplasms
In situ localization of gelatinolytic activity in the extracellular matrix of metastases of colon cancer in rat liver using quenched fluorogenic DQ-gelatin.
Colonic Neoplasms
Increased gelatinase A (MMP-2) and cathepsin B activity in invasive tumor regions of human colon cancer samples.
Colonic Neoplasms
Inhibition of arachidonic acid metabolism decreases tumor cell invasion and matrix metalloproteinase expression.
Colonic Neoplasms
Inhibition of Experimental Colon Cancer Metastasis by the GABA-Receptor Agonist Nembutal.
Colonic Neoplasms
Inhibitory effect of a gamma-oryzanol-rich fraction from purple rice extract on lipopolysaccharide-induced metastasis in human colon cancer cells.
Colonic Neoplasms
Inhibitory effect of a selective cyclooxygenase-2 inhibitor on liver metastasis of colon cancer.
Colonic Neoplasms
Klotho suppresses growth and invasion of colon cancer cells through inhibition of IGF1R-mediated PI3K/AKT pathway.
Colonic Neoplasms
Knockdown GREM1 suppresses cell growth, angiogenesis, and epithelial-mesenchymal transition in colon cancer.
Colonic Neoplasms
M(r) 92,000 type IV collagenase is increased in plasma of patients with colon cancer and breast cancer.
Colonic Neoplasms
M2-like macrophages induce colon cancer cell invasion via matrix metalloproteinases.
Colonic Neoplasms
Matrix metalloproteinase-2 cleavage of the ?1 integrin ectodomain facilitates colon cancer cell motility.
Colonic Neoplasms
Matrix metalloproteinase-2 expression in stromal tissues is a consistent prognostic factor in stage II colon cancer.
Colonic Neoplasms
Microenvironment influence on human colon adenocarcinoma phenotypes and matrix metalloproteinase-2, p53 and ?-catenin tumor expressions from identical monoclonal cell tumor in the orthotopic model in athymic nude rats.
Colonic Neoplasms
MicroRNA-340 inhibits the proliferation and promotes the apoptosis of colon cancer cells by modulating REV3L.
Colonic Neoplasms
MMP-9-hemopexin domain hampers adhesion and migration of colorectal cancer cells.
Colonic Neoplasms
Modulation of the invasive phenotype of human colon carcinoma cells by organ specific fibroblasts of nude mice.
Colonic Neoplasms
Ornithine decarboxylase, mitogen-activated protein kinase and matrix metalloproteinase-2 expressions in human colon tumors.
Colonic Neoplasms
p38? MAPK Mediates 17?-Estradiol Inhibition of MMP-2 and -9 Expression and Cell Migration in Human LoVo Colon Cancer Cells.
Colonic Neoplasms
Phenethyl Isothiocyanate Inhibited Tumor Migration and Invasion via Suppressing Multiple Signal Transduction Pathways in Human Colon Cancer HT29 Cells.
Colonic Neoplasms
Platelet aggregation-induced by caco-2 cells: regulation by matrix metalloproteinase-2 and adenosine diphosphate.
Colonic Neoplasms
Polymorphisms in MMP-1, MMP-2, MMP-7, MMP-13 and MT2A do not contribute to breast, lung and colon cancer risk in polish population.
Colonic Neoplasms
Prognostic significance of matrix metalloproteinases-1, -2, -7 and -13 and tissue inhibitors of metalloproteinases-1, -2, -3 and -4 in colorectal cancer.
Colonic Neoplasms
Protein arginine methyltransferase 5 is implicated in the aggressiveness of human hepatocellular carcinoma and controls the invasive activity of cancer cells.
Colonic Neoplasms
Reduction of in vivo tumor growth by MMI-166, a selective matrix metalloproteinase inhibitor, through inhibition of tumor angiogenesis in squamous cell carcinoma cell lines of head and neck.
Colonic Neoplasms
ROCK-II mediates colon cancer invasion via regulation of MMP-2 and MMP-13 at the site of invadopodia as revealed by multiphoton imaging.
Colonic Neoplasms
Role of endothelin a receptor in colon cancer metastasis: In vitro and in vivo evidence.
Colonic Neoplasms
RUNX3 Inhibits the Invasion and Metastasis of Human Colon Cancer HT-29 Cells by Upregulating MMP-2/9.
Colonic Neoplasms
Silibinin inhibits the invasion of IL-6-stimulated colon cancer cells via selective JNK/AP-1/MMP-2 modulation in vitro.
Colonic Neoplasms
Small integrin binding ligand N-linked glycoprotein gene family expression in different cancers.
Colonic Neoplasms
Spectrum of matrix metalloproteinase expression in primary and metastatic colon cancer: relationship to the tissue inhibitors of metalloproteinases and membrane type-1-matrix metalloproteinase.
Colonic Neoplasms
Tetrandrine suppresses adhesion, migration and invasion of human colon cancer SW620 cells via inhibition of nuclear factor-?B, matrix metalloproteinase-2 and matrix metalloproteinase-9 signaling pathways.
Colonic Neoplasms
The clinical significance and biological function of tropomyosin 4 in colon cancer.
Colonic Neoplasms
The expression of STAT3, BCL-XL and MMP-2 proteins in colon adenocarcinomas and their relationship with prognostic factors.
Colonic Neoplasms
The Immunohistochemical Expression of STAT3, Bcl-xL, and MMP-2 Proteins in Colon Adenoma and Adenocarcinoma.
Colonic Neoplasms
The traditional Chinese medicine Achyranthes bidentata and our de novo conception of its metastatic chemoprevention: from phytochemistry to pharmacology.
Colonic Neoplasms
Transforming growth factor-beta1 modulates metalloproteinase-2 and -9, nitric oxide, RhoA and alpha-smooth muscle actin expression in colon adenocarcinoma cells.
Colonic Neoplasms
[Effects of phosphatase of regenerating liver cell-3 gene silence by RNA interference on the expression of matrix metalloproteinases-2,-9 in human colon cancer cells]
Colonic Neoplasms
[Expression and clinical significance of kisspeptin-1, matrix metalloproteinase-2 and vascular endothelial growth factor in tissue of colon cancer].
Colonic Neoplasms
[Expression of MMP-2, HIF-1alpha and VEGF in Colon Adenoma and Colon Cancer.]
Colonic Neoplasms
[State of the liver antioxidant system and content of matrix metalloproteinase-2 of the large intestine under the effect of maleimide derivative in experimental colorectal carcinogenesis in rats].
Colorectal Neoplasms
(-)-Epigallocatechin-3-gallate promotes pro-matrix metalloproteinase-7 production via activation of the JNK1/2 pathway in HT-29 human colorectal cancer cells.
Colorectal Neoplasms
A prospective study of prognostic value of type IV collagenase activity in colorectal cancer tissue.
Colorectal Neoplasms
A single nucleotide polymorphism in the matrix metalloproteinase-2 promoter is associated with colorectal cancer.
Colorectal Neoplasms
Active matrix metalloproteinase-2 activity discriminates colonic mucosa, adenomas with and without high-grade dysplasia, and cancers.
Colorectal Neoplasms
Active MMP-2 effectively identifies the presence of colorectal cancer.
Colorectal Neoplasms
Activity and expression of urokinase-type plasminogen activator and matrix metalloproteinases in human colorectal cancer.
Colorectal Neoplasms
Antitumor activity of anti-type IV collagenase monoclonal antibody and its lidamycin conjugate against colon carcinoma.
Colorectal Neoplasms
Association of matrix metalloproteinase-2 and -9 promoter polymorphisms with colorectal cancer in Chinese.
Colorectal Neoplasms
Associations between single nucleotide polymorphisms of COX-2 and MMP-2 genes and colorectal cancer susceptibility in the Saudi population.
Colorectal Neoplasms
Associations between Single Nucleotide Polymorphisms of MMP2, VEGF, and HIF1A Genes and the Risk of Developing Colorectal Cancer.
Colorectal Neoplasms
Balance between activation and inhibition of matrix metalloproteinase-2 (MMP-2) is altered in colorectal tumors compared to normal colonic epithelium.
Colorectal Neoplasms
Behaviour of basement membrane antigens in gastric and colorectal cancer. Immunohistochemical study.
Colorectal Neoplasms
Carcinoembryonic antigen and matrix metalloproteinase 2 serum and peritoneal washes concentration in staging and prognosis in colorectal cancer patients.
Colorectal Neoplasms
Celecoxib inhibits tumor growth and angiogenesis in an orthotopic implantation tumor model of human colon cancer.
Colorectal Neoplasms
Changes in extracellular matrix in different stages of colorectal cancer and their effects on proliferation of cancer cells.
Colorectal Neoplasms
Circulating gelatinases and tissue inhibitor of metalloproteinase-1 in colorectal cancer metastatic liver disease.
Colorectal Neoplasms
Clinical relevance of MMP-9, MMP-2, TIMP-1 and TIMP-2 in colorectal cancer.
Colorectal Neoplasms
Clinicopathologic and Prognostic Significance of Gelatinase A in Tunisian Colorectal Cancer: A Case-Control Study.
Colorectal Neoplasms
Clinicopathological assessment and quantitative estimation of the matrix metalloproteinases MMP-2 and MMP-7 and the inhibitors TIMP-1 and TIMP-2 in colorectal carcinoma tissue samples.
Colorectal Neoplasms
Clinicopathological significance of the gene expression of matrix metalloproteinases and reversion-inducing cysteine-rich protein with Kazal motifs in patients with colorectal cancer: MMP-2 gene expression is a useful predictor of liver metastasis from colorectal cancer.
Colorectal Neoplasms
Correlation of reversion-inducing cysteine-rich protein with kazal motifs (RECK) and extracellular matrix metalloproteinase inducer (EMMPRIN), with MMP-2, MMP-9, and survival in colorectal cancer.
Colorectal Neoplasms
Correlations of serum VEGF and MMP-2 levels with CLM in CRC patients and effects of TACE on their expressions.
Colorectal Neoplasms
Correspondence re: N-B. Liabakk et al., matrix metalloprotease 2 (MMP-2) and matrix metalloprotease 9 (MMP-9) type IV collagenases in colorectal cancer. Cancer Res., 56: 190-196, 1966.
Colorectal Neoplasms
Cudratricusxanthone G inhibits human colorectal carcinoma cell invasion by MMP-2 down-regulation through suppressing activator protein-1 activity.
Colorectal Neoplasms
Cyclooxygenase-2 expression correlates with membrane-type-1 matrix metalloproteinase expression in colorectal cancer tissue.
Colorectal Neoplasms
Cyclooxygenase-2 inhibition prevents migration of colorectal cancer cells to extracellular matrix by down-regulation of matrix metalloproteinase-2 expression.
Colorectal Neoplasms
Cyclooxygenase-2/Carbonic anhydrase-IX up-regulation promotes invasive potential and hypoxia survival in colorectal cancer cells.
Colorectal Neoplasms
Enhanced expression of MMP-7 and MMP-13 in inflammatory bowel disease: a precancerous potential?
Colorectal Neoplasms
Enhanced expression of tissue inhibitors of metalloproteinases in human colorectal tumors.
Colorectal Neoplasms
Evaluation of the expression of metalloproteinases 2 and 9 and their tissue inhibitors in colon cancer cells treated with phytic acid.
Colorectal Neoplasms
Expression and localization of matrix metalloproteinases and tissue inhibitors of metalloproteinases as a prognostic factor in advanced colorectal carcinomas.
Colorectal Neoplasms
Expression of COX-2, MMP-2 and VEGF in stage II and III colorectal cancer and the clinical significance.
Colorectal Neoplasms
Expression of gelatinase-A (MMP-2) in human colon cancer and normal colon mucosa.
Colorectal Neoplasms
Expression of matrix metalloproteinases 2, 7 and 9 in patients with colorectal cancer.
Colorectal Neoplasms
Expression of tissue inhibitor of metalloproteinases TIMP-2 in human colorectal cancer--a predictor of tumour stage.
Colorectal Neoplasms
Expression profiling using a cDNA array and immunohistochemistry for the extracellular matrix genes FN-1, ITGA-3, ITGB-5, MMP-2, and MMP-9 in colorectal carcinoma progression and dissemination.
Colorectal Neoplasms
Genetic Modification of Cell Lines to Enhance Their Metastatic Capability.
Colorectal Neoplasms
Genetic polymorphisms of matrix metalloproteinases in lung, breast and colorectal cancer.
Colorectal Neoplasms
High expression of matrix metalloproteinases: MMP-2 and MMP-9 predicts poor survival outcome in colorectal carcinoma.
Colorectal Neoplasms
High molecular weight coffee melanoidins are inhibitors for matrix metalloproteases.
Colorectal Neoplasms
Host expression of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in normal colon tissue affects metastatic potential of colorectal cancer.
Colorectal Neoplasms
Hyaluronan preconditioning of monocytes/macrophages affects their angiogenic behavior and regulation of TSG-6 expression in a tumor type-specific manner.
Colorectal Neoplasms
Immunohistochemical detection of membrane-type-1-matrix metalloproteinase in colorectal carcinoma.
Colorectal Neoplasms
In vitro determination of basement membrane invasion predicts liver metastases in human gastrointestinal carcinoma.
Colorectal Neoplasms
Increased activity of matrix metalloproteinase 2 and 9 after hepatic radiofrequency ablation.
Colorectal Neoplasms
Increased expression of the Mr 72,000 type IV collagenase in human colonic adenocarcinoma.
Colorectal Neoplasms
Increased matrix metalloproteinase 2 concentration and transcript expression in advanced colorectal carcinomas.
Colorectal Neoplasms
Increased plasma MMP-2 protein expression in lymph node-positive patients with colorectal cancer.
Colorectal Neoplasms
Increased serum type IV collagen 7-S levels in patients with hepatic metastasis.
Colorectal Neoplasms
Increased Sushi repeat-containing protein X-linked 2 is associated with progression of colorectal cancer.
Colorectal Neoplasms
Inhibition of organ invasion by the matrix metalloproteinase inhibitor batimastat (BB-94) in two human colon carcinoma metastasis models.
Colorectal Neoplasms
Inhibitory Effects of Dried Longan (Euphoria longana Lam.) Seed Extract on Invasion and Matrix Metalloproteinases of Colon Cancer Cells.
Colorectal Neoplasms
Ito cell morphology, alpha-smooth muscle actin and collagen type IV expression in the liver of patients with gastric and colorectal tumors.
Colorectal Neoplasms
Knockdown of LI-cadherin alters expression of matrix metalloproteinase-2 and -9 and galectin-3.
Colorectal Neoplasms
Knockdown of Li-cadherin increases metastatic behaviors of LoVo cells.
Colorectal Neoplasms
Laminin-5 gamma 2 chain and matrix metalloproteinase-2 may trigger colorectal carcinoma invasiveness through formation of budding tumor cells.
Colorectal Neoplasms
Letter to the editor: a meta-analysis of MMP-2 expression on the survival of patients with colorectal cancer.
Colorectal Neoplasms
Limited value of preoperative serum analyses of matrix metalloproteinases (MMP-2, MMP-9) and tissue inhibitors of matrix metalloproteinases (TIMP-1, TIMP-2) in colorectal cancer.
Colorectal Neoplasms
Loss of basement membrane type IV collagen is associated with increased expression of metalloproteinases 2 and 9 (MMP-2 and MMP-9) during human colorectal tumorigenesis.
Colorectal Neoplasms
Matrix metalloprotease 2 (MMP-2) and matrix metalloprotease 9 (MMP-9) type IV collagenases in colorectal cancer.
Colorectal Neoplasms
Matrix metalloproteinase 2 and 9 activity in patients with colorectal cancer liver metastasis.
Colorectal Neoplasms
Matrix metalloproteinase 2 and tissue inhibitor of matrix metalloproteinases 2 in the diagnosis of colorectal adenoma and cancer patients.
Colorectal Neoplasms
Matrix metalloproteinase 2 overexpression and prognosis in colorectal cancer: a meta-analysis.
Colorectal Neoplasms
Matrix metalloproteinase 2 promotes cell growth and invasion in colorectal cancer.
Colorectal Neoplasms
Matrix metalloproteinase-2 (-1306 c>t) promoter polymorphism and risk of colorectal cancer in the Saudi population.
Colorectal Neoplasms
Matrix metalloproteinase-2 (MMP-2) and -9 (MMP-9) in preoperative serum as independent prognostic markers in patients with colorectal cancer.
Colorectal Neoplasms
Matrix metalloproteinase-2 and -9 in bile as a marker of liver metastasis in colorectal cancer.
Colorectal Neoplasms
Matrix Metalloproteinase-2 and -9, Lactate, and Malate Dehydrogenase and Lipid Peroxides in Sera of Patients with Colorectal Carcinoma.
Colorectal Neoplasms
Matrix metalloproteinase-2 and tissue inhibitor of metallo-proteinase-2 in colorectal carcinoma invasion and metastasis.
Colorectal Neoplasms
Matrix metalloproteinase-2 cleavage of the ?1 integrin ectodomain facilitates colon cancer cell motility.
Colorectal Neoplasms
Matrix metalloproteinase-9 activity is associated with poor prognosis in T3-T4 node-negative colorectal cancer.
Colorectal Neoplasms
Matrix metalloproteinase/tissue inhibitors of matrix metalloproteinase phenotype identifies poor prognosis colorectal cancers.
Colorectal Neoplasms
Matrix metalloproteinases in Vietnamese patients with colorectal cancer.
Colorectal Neoplasms
Matrix metalloproteinases may contribute compensationally to tumor invasion in T1 colorectal carcinomas.
Colorectal Neoplasms
MFG-E8 overexpression promotes colorectal cancer progression via AKT/MMPs signalling.
Colorectal Neoplasms
MicroRNA-29a promotes colorectal cancer metastasis by regulating matrix metalloproteinase 2 and E-cadherin via KLF4.
Colorectal Neoplasms
MMP-2 and MMP-9 in normal mucosa are independently associated with outcome of colorectal cancer patients.
Colorectal Neoplasms
MMP-2 geno-phenotype is prognostic for colorectal cancer survival, whereas MMP-9 is not.
Colorectal Neoplasms
MMP-2, -3 and TIMP-2, -3 polymorphisms in colorectal cancer in a Chinese Han population: A case-control study.
Colorectal Neoplasms
Multi-layered proteogenomic analysis unravels cancer metastasis directed by MMP-2 and focal adhesion kinase signaling.
Colorectal Neoplasms
Myricetin inhibits matrix metalloproteinase 2 protein expression and enzyme activity in colorectal carcinoma cells.
Colorectal Neoplasms
Naturally occurring glycyrrhizin triterpene exerts anticancer effects on colorectal cancer cells via induction of apoptosis and autophagy and suppression of cell migration and invasion by targeting MMP-9 and MMP-2 expression.
Colorectal Neoplasms
Netrin-1 plays a role in the effect of moderate exercise on myocardial fibrosis in rats.
Colorectal Neoplasms
Occurrence of an active form of gelatinase in human gastric and colorectal carcinoma tissues.
Colorectal Neoplasms
Plasma gelatinase activity does not reflect disease activity after operation for colorectal cancer.
Colorectal Neoplasms
Plasma levels of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-1 correlate with disease stage and survival in colorectal cancer patients.
Colorectal Neoplasms
Polymorphisms of matrix metalloproteinases 1, 2, 3 and 9 and susceptibility to lung, breast and colorectal cancer in over 30,000 subjects.
Colorectal Neoplasms
Preoperative plasma MMP-2 expression is prognostic in colorectal cancer.
Colorectal Neoplasms
Prognostic and diagnostic implications of MMP-2, MMP-9, and VEGF-? expressions in colorectal cancer.
Colorectal Neoplasms
Prognostic significance of matrix metalloproteinase expression in colorectal carcinomas.
Colorectal Neoplasms
Prognostic significance of matrix metalloproteinase-2, cathepsin D, and tenascin-C expression in colorectal carcinoma.
Colorectal Neoplasms
Quantitative estimation of matrix metalloproteinases 2 and 7 (MMP-2, MMP-7) and tissue inhibitors of matrix metalloproteinases 1 and 2 (TIMP-1, TIMP-2) in colorectal carcinoma tissue samples.
Colorectal Neoplasms
Relationship between single-nucleotide polymorphism of matrix metalloproteinase-2 gene and colorectal cancer and gastric cancer susceptibility: a meta-analysis.
Colorectal Neoplasms
Relevance of biologic markers in colorectal carcinoma: a comparative study of a broad panel.
Colorectal Neoplasms
S-adenosylmethionine, a methyl donor, up regulates tissue inhibitor of metalloproteinase-2 in colorectal cancer.
Colorectal Neoplasms
Serum levels and tissue expression of matrix metalloproteinase 2 (MMP-2) and tissue inhibitor of metalloproteinases 2 (TIMP-2) in colorectal cancer patients.
Colorectal Neoplasms
Speckle-Type POZ Protein Down-Regulates Matrix Metalloproteinase 2 Expression via Sp1/PI3K/Akt Signaling Pathway in Colorectal Cancer.
Colorectal Neoplasms
Spectrum of matrix metalloproteinase expression in primary and metastatic colon cancer: relationship to the tissue inhibitors of metalloproteinases and membrane type-1-matrix metalloproteinase.
Colorectal Neoplasms
Stromal expression of 72 kda type IV collagenase (MMP-2) and TIMP-2 mRNAs in colorectal neoplasia.
Colorectal Neoplasms
Stromelysin-1 promoter mutations impair gelatinase B activation in high microsatellite instability sporadic colorectal tumors.
Colorectal Neoplasms
Synergistic efficacy of Cullin1 and MMP-2 expressions in diagnosis and prognosis of colorectal cancer.
Colorectal Neoplasms
Targeted MMP-2 responsive chimeric polymersomes for therapy against colorectal cancer.
Colorectal Neoplasms
The expression of MMP-2 and TIMP-2 in patients with colorectal adenocarcinoma invaded to the submucosal and proper muscle layer.
Colorectal Neoplasms
The expression of MMP-2 and TIMP-2 in patients with primary colorectal adenocarcinoma: correlation with liver metastasis.
Colorectal Neoplasms
The relation of gelatinase (MMP-2 and -9) expression with distant site metastasis and tumour aggressiveness in colorectal cancer.
Colorectal Neoplasms
The role of gelatinases in colorectal cancer progression and metastasis.
Colorectal Neoplasms
Tissue levels of active matrix metalloproteinase-2 and -9 in colorectal cancer.
Colorectal Neoplasms
TRIB1 promotes colorectal cancer cell migration and invasion through activation MMP-2 via FAK/Src and ERK pathways.
Colorectal Neoplasms
Twist1/2 activates MMP2 expression via binding to its promoter in colorectal cancer.
Colorectal Neoplasms
Up-regulation of gelatinases in the colorectal adenoma-carcinoma sequence.
Colorectal Neoplasms
Upregulation of nemo-like kinase is an independent prognostic factor in colorectal cancer.
Colorectal Neoplasms
Use of plasma MMP-2 and MMP-9 levels as a surrogate for tumour expression in colorectal cancer patients.
Colorectal Neoplasms
VEGF release by MMP-9 mediated heparan sulphate cleavage induces colorectal cancer angiogenesis.
Colorectal Neoplasms
[Expression of LOX in Colorectal Cancer Tissues and Its Relationship with Progress and Prognosis].
Colorectal Neoplasms
[Expression of matrix metalloproteinases and tissue inhibitor of metalloproteinases in colorectal neoplasm]
Colorectal Neoplasms
[Expression of MMP-2, MMP-9 and collagen type IV and their relationship in colorectal carcinomas.]
Colorectal Neoplasms
[Implication of VEGF and MMPs in hepatic metastasis of human colon cancer]
Colorectal Neoplasms
[Short hairpin RNA-mediated suvivin gene silencing inhibits invasion and metastasis of human colon carcinoma cell line SW480 in vitro]
Colorectal Neoplasms
[The correlation between polymorphisms of matrix metalloproteinase-2 and -9 genes and colorectal cancer of Chinese patients]
Colorectal Neoplasms
[Type IV collagenase activities in human colorectal cancers and its role in cancer invasion and metastasis]
Colorectal Neoplasms
[Type IV collagenase activities in human colorectal carcinomas and its role in hepatic metastasis: preliminary report]
Common Cold
MicroRNA-124-3p inhibits the growth and metastasis of nasopharyngeal carcinoma cells by targeting STAT3.
Complex Regional Pain Syndromes
Local and Systemic Expression Pattern of MMP-2 and MMP-9 in Complex Regional Pain Syndrome.
Confusion
Areca nut procyanidins prevent ultraviolet light B-induced photoaging via suppression of cyclooxygenase-2 and matrix metalloproteinases in mouse skin.
Conjunctivitis, Allergic
Activation of corneal fibroblast-derived matrix metalloproteinase-2 by tryptase.
Conjunctivitis, Allergic
Active matrix metalloproteinases in the tear fluid of individuals with vernal keratoconjunctivitis.
Connective Tissue Diseases
Autoactivation profiles of calcium-dependent matrix metalloproteinase-2 and -9 in inflammatory synovial fluid: effect of pyrophosphate and bisphosphonates.
Connective Tissue Diseases
Zymographic analysis of latent and activated forms of matrix metalloproteinase-2 and -9 in synovial fluid: correlation to polymorphonuclear leukocyte infiltration and in response to infection.
Contracture
Effect of Tissue Inhibitors of Metalloproteinases and Matrix Metalloproteinases on Capsular Formation Around Smooth and Textured Silicone Gel Implants.
Contracture
Matrix metalloproteinases, tissue inhibitors of metalloproteinases, aminoterminal propeptide of procollagen type III, and hyaluronan in sera and tissue of patients with capsular contracture after augmentation with Trilucent breast implants.
Corneal Injuries
Expression of matrix metalloproteinases 2 and 9 in experimental corneal injury and fungal keratitis.
Corneal Neovascularization
Controlling herpes simplex virus-induced ocular inflammatory lesions with the lipid-derived mediator resolvin E1.
Corneal Neovascularization
Corneal angiogenic privilege: angiogenic and antiangiogenic factors in corneal avascularity, vasculogenesis, and wound healing (an American Ophthalmological Society thesis).
Corneal Neovascularization
Delayed inflammation-associated corneal neovascularization in MMP-2-deficient mice.
Corneal Neovascularization
Expression of matrix metalloproteinase-2 (MMP-2) and vascular endothelial growth factor (VEGF) in inflammation-associated corneal neovascularization.
Corneal Neovascularization
Expression of matrix metalloproteinases 2 and 9 and tissue inhibitors of metalloproteinase 1 and 2 in inflammation-induced corneal neovascularization.
Corneal Neovascularization
Regulation of Matrix Metalloproteinase 2 and 9 in Corneal Neovascularization.
Corneal Ulcer
Active form of gelatinases in tear fluidin patients with corneal ulcer or ocular burn.
Corneal Ulcer
Matrix metalloproteinases (MMP-2 and MMP-9) activity in corneal ulcer and ocular surface disorders determined by gelatin zymography.
Coronary Aneurysm
Systemic arterial expression of matrix metalloproteinases 2 and 9 in acute Kawasaki disease.
Coronary Artery Disease
A haplotype constituted of four MMP-2 promoter polymorphisms (-1575G/A, -1306C/T, -790T/G and -735C/T) is associated with coronary triple-vessel disease.
Coronary Artery Disease
Matrix Metalloproteinase-2 Polymorphisms and Incident Coronary Artery Disease: A Meta-Analysis.
Coronary Artery Disease
MMP-2, MMP-9, and TIMP-4 and Response to Aspirin in Diabetic and Nondiabetic Patients with Stable Coronary Artery Disease: A Pilot Study.
Coronary Artery Disease
Neutrophil Gelatinase Associated Lipocalin (NGAL) as a Biomarker. Does It Apply in Abdominal Aortic Aneurysms? A Review of Literature.
Coronary Artery Disease
New insights into molecular mechanisms of diffuse coronary ectasiae: a possible role for VEGF.
Coronary Artery Disease
Plasma matrix metalloproteinase-9 and left ventricular remodelling after acute myocardial infarction in man: a prospective cohort study.
Coronary Artery Disease
Plasma matrix metalloproteinase-9, tissue inhibitor of metalloproteinase-2, and CD40 ligand levels in patients with stable coronary artery disease.
Coronary Artery Disease
Polymorphisms in the promoter regions of MMP-2, MMP-3, MMP-9 and MMP-12 genes as determinants of aneurysmal coronary artery disease.
Coronary Artery Disease
Progression of kidney disease in non-diabetic patients with coronary artery disease: predictive role of circulating matrix metalloproteinase-2, -3, and -9.
Coronary Artery Disease
Serum levels of gelatinase associated lipocalin as indicator of the inflammatory status in coronary artery disease.
Coronary Artery Disease
Soluble P-selectin and matrix metalloproteinase 2 levels are elevated in patients with diastolic dysfunction independent of glucose metabolism disorder or coronary artery disease.
Coronary Artery Disease
The role of matrix metalloproteinase-2 promoter polymorphisms in coronary artery disease and myocardial infarction.
Coronary Artery Disease
Urinary levels of matrix metalloproteinase 9 and 2 and tissue inhibitor of matrix metalloproteinase in patients with coronary artery disease.
Coronary Artery Disease
Vitamin D is related to markers of vulnerable plaque in acute myocardial infarction.
Coronary Artery Disease
[Changes in serum level of carboxy-terminal telopeptide of type I collagen in patients with coronary heart disease].
Coronary Disease
A haplotype constituted of four MMP-2 promoter polymorphisms (-1575G/A, -1306C/T, -790T/G and -735C/T) is associated with coronary triple-vessel disease.
Coronary Disease
Angiotensin II Induces an Increase in Matrix Metalloproteinase 2 Expression in Aortic Smooth Muscle Cells of Ascending Thoracic Aortic Aneurysms Through JNK, ERK1/2, and p38 MAPK Activation.
Coronary Disease
Angiotensin II Induces the Vascular Expression of VEGF and MMP-2 in vivo: Preventive Effect of Red Wine Polyphenols.
Coronary Disease
Carotid thickness and atherosclerotic plaque stability, serum inflammation, serum MMP-2 and MMP-9 were associated with acute cerebral infarction.
Coronary Disease
Correlation between plasma angiopoietin-1, angiopoietin-2 and matrix metalloproteinase-2 in coronary heart disease.
Coronary Disease
Elevated circulating levels of matrix metalloproteinase-9 and -2 in patients with symptomatic coronary artery disease.
Coronary Disease
[Analysis of the gene polymorphism of matrix metalloproteinase-2 and -9 in patients with coronary heart disease]
Coronary Stenosis
Metalloproteases 2 and 9, Lp-PLA(2) and lipoprotein profile in coronary patients.
Cough
Predictors of exacerbations in chronic obstructive pulmonary disease--results from the Bergen COPD cohort study.
COVID-19
Matrix metalloproteinases are involved in the development of neurological complications in patients with Coronavirus disease 2019.
COVID-19
MMP-2 and MMP-9 levels in plasma are altered and associated with mortality in COVID-19 patients.
Crohn Disease
Elevated plasma gelatinase A (MMP-2) activity is associated with quiescent Crohn's Disease.
Crohn Disease
Enhanced expression of MMP-7 and MMP-13 in inflammatory bowel disease: a precancerous potential?
Crohn Disease
Expression and regulation of tissue inhibitor of metalloproteinase-1 and matrix metalloproteinases by intestinal myofibroblasts in inflammatory bowel disease.
Crohn Disease
Expression of protease-activated receptor-1 and -2 in orofacial granulomatosis.
Crohn Disease
Expressions of Matrix Metalloproteinases (MMP-2, MMP-7, and MMP-9) and Their Inhibitors (TIMP-1, TIMP-2) in Inflammatory Bowel Diseases.
Crohn Disease
Increased incidence of urinary matrix metalloproteinases as predictors of disease in pediatric patients with inflammatory bowel disease.
Crohn Disease
P269. Serum neutrophil gelatinase B-associated lipocalin and matrix metalloproteinase-9 (NGAL-MMP-9) complex as a surrogate marker for mucosal healing in patients with Crohn's disease.
Crohn Disease
Role of N-acetylcysteine and GSH redox system on total and active MMP-2 in intestinal myofibroblasts of Crohn's disease patients.
Crohn Disease
Serum Neutrophil Gelatinase B-associated Lipocalin and Matrix Metalloproteinase-9 Complex as a Surrogate Marker for Mucosal Healing in Patients with Crohn's Disease.
Cryptogenic Organizing Pneumonia
Characteristic elevation of matrix metalloproteinase activity in idiopathic interstitial pneumonias.
Cryptogenic Organizing Pneumonia
Localization of matrix metalloproteinases-1, -2, and -9 and tissue inhibitor of metalloproteinase-2 in interstitial lung diseases.
Cryptorchidism
Plasma concentration of MMP-1 and MMP-2 in boys with cryptorchidism and its lack of correlation with INSL3 and inhibin B.
Cutis Laxa
Cutis Laxa: analysis of metalloproteinases and extracellular matrix expression by immunohistochemistry and histochemistry.
Cutis Laxa
Regulation of matrix metalloproteinase (MMP) expression in cutis laxa fibroblasts: upregulation of MMP-1, MMP-3 and MMP-9 genes but not of the MMP-2 gene.
Cystadenocarcinoma
72-kilodalton type IV collagenase, type IV collagen, and Ki 67 antigen in serous tumors or the ovary: a clinicopathologic, immunohistochemical, and Serological study.
Cystadenocarcinoma
Increased serum 72 KDa metalloproteinase in serous ovarian tumors: comparison with CA 125.
Cystadenocarcinoma, Serous
Tissue and serum metalloproteinase (MMP-2) expression in advanced ovarian serous cystoadenocarcinomas: clinical and prognostic implications.
Cystadenoma
72-kilodalton type IV collagenase, type IV collagen, and Ki 67 antigen in serous tumors or the ovary: a clinicopathologic, immunohistochemical, and Serological study.
Cystadenoma
Evaluation of basement membrane components and the 72 kDa type IV collagenase in serous tumors of the ovary.
Cystadenoma
Increased expression of matrix metalloproteinases (MMP)-2, MMP-9, and the urokinase-type plasminogen activator is associated with progression from benign to advanced ovarian cancer.
Cystadenoma
Increased serum 72 KDa metalloproteinase in serous ovarian tumors: comparison with CA 125.
Cystadenoma
Tissue and serum metalloproteinase (MMP-2) expression in advanced ovarian serous cystoadenocarcinomas: clinical and prognostic implications.
Cystic Fibrosis
Imbalance between 95 kDa type IV collagenase and tissue inhibitor of metalloproteinases in sputum of patients with cystic fibrosis.
Cystic Fibrosis
Matrix metalloproteinase activation by free neutrophil elastase contributes to bronchiectasis progression in early cystic fibrosis.
Cystic Fibrosis
Study of biological characteristics of Pseudomonas aeruginosa strains isolated from patients with cystic fibrosis and from patients with extra-pulmonary infections.
Cysts
Adhesion molecules, chemokines and matrix metallo-proteinases response after albendazole and albendazole plus steroid therapy in swine neurocysticercosis.
Cysts
Analyses of matrix metalloproteinases and their inhibitors in cyst fluid of serous ovarian tumors.
Cysts
Cystic vestibular schwannomas: a possible role of matrix metalloproteinase-2 in cyst development and unfavorable surgical outcome.
Cysts
Difference in expression of matrix metalloproteinase-2 and matrix metalloproteinase-9 in patients with persistent ovarian cysts.
Cysts
Doxycycline use in patients with lymphangioleiomyomatosis: safety and efficacy in metalloproteinase blockade.
Cysts
Entamoeba invadens: cysteine protease inhibitors block excystation and metacystic development.
Cysts
Expression of adhesion molecules, chemokines and matrix metallo- proteinases (MMPs) in viable and degenerating stage of Taenia solium metacestode in swine neurocysticercosis.
Cysts
Expression of matrix metalloproteinases and related tissue inhibitors in the cyst fluids of ovarian mucinous neoplasms.
Cysts
Immunoexpression of the PTEN protein and matrix metalloproteinase-2 in endometrial cysts, endometrioid and clear cell ovarian cancer.
Cysts
Immunohistochemical study of matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) in pulmonary lymphangioleiomyomatosis (LAM).
Cysts
Increased expression of intracystic matrix metalloproteinases in brain tumors: relationship to the pathogenesis of brain tumor-associated cysts and peritumoral edema.
Cysts
Increased matrix metalloproteinase-2 activity induced by TGF-beta 1 in duct cells of human salivary gland is associated with the development of cyst formation in vivo.
Cysts
Involvement of Matrix Metalloproteinases and their Inhibitors in Bovine Cystic Ovarian Disease.
Cysts
Laminin-5 gamma 2 chain is colocalized with gelatinase-A (MMP-2) and collagenase-3 (MMP-13) in odontogenic keratocysts.
Cysts
Marked induction of gelatinases, especially type B, in host fibroblasts by human ovarian cancer cells in athymic mice.
Cysts
Matrix metalloproteinase-2 in a murine model of infantile-type polycystic kidney disease.
Cysts
Membrane-type-1 matrix metalloproteinase confers tumorigenicity on nonmalignant epithelial cells.
Cysts
Neutrophil gelatinase-associated lipocalin suppresses cyst growth by Pkd1 null cells in vitro and in vivo.
Cysts
Significance of matrix metalloproteinases in the pathophysiology of the ovary and uterus.
Cysts
The levels of trypsinogen isoenzymes in ovarian tumour cyst fluids are associated with promatrix metalloproteinase-9 but not promatrix metalloproteinase-2 activation.
Cysts
Tubular gelatinase A (MMP-2) and its tissue inhibitors in polycystic kidney disease in the Han:SPRD rat.
Cytomegalovirus Infections
[Effect of cytomegalovirus infection on expression of matrix metalloproteinase-2 in human endothelial cells.]
Dementia
Cerebrospinal fluid levels of MMP-2, 7, and 9 are elevated in association with human immunodeficiency virus dementia.
Dementia
Concentrations of Matrix Metalloproteinases and their Tissue Inhibitors in the Cerebrospinal Fluid of Patients with Alzheimer's Disease.
Dementia
Evaluation of HIV RNA and markers of immune activation as predictors of HIV-associated dementia.
Dementia
Evaluation of Matrix Metalloproteinase-2 (MMP-2) and -9 (MMP-9) and Their Tissue Inhibitors (TIMP-1 and TIMP-2) in Plasma from Patients with Neurodegenerative Dementia.
Dementia
Increased activity of matrix metalloproteinases in the cerebrospinal fluid of patients with HIV-associated neurological diseases.
Dementia
Lentivirus infection in the brain induces matrix metalloproteinase expression: role of envelope diversity.
Dementia
Local delivery of protease-resistant stromal cell derived factor-1 for stem cell recruitment after myocardial infarction.
Dementia
Profiles of matrix metalloproteinases and their inhibitors in plasma of patients with dementia.
Dementia
The role of matrix metalloproteinases and tissue inhibitors of metalloproteinases in the pathophysiology of neurodegeneration: a literature study.
Dementia, Vascular
Profiles of matrix metalloproteinases and their inhibitors in plasma of patients with dementia.
Demyelinating Diseases
Matrix metalloproteinase upregulation in chronic inflammatory demyelinating polyneuropathy and nonsystemic vasculitic neuropathy.
Demyelinating Diseases
Matrix metalloproteinase-2 is involved in myelination of dorsal root ganglia neurons.
Demyelinating Diseases
Matrix metalloproteinases MMP-9 and MMP-7 are expressed in experimental autoimmune neuritis and the Guillain-Barré syndrome.
Demyelinating Diseases
MMP-12, MMP-3, and TIMP-1 are markedly upregulated in chronic demyelinating theiler murine encephalomyelitis.
Demyelinating Diseases
Zymographic patterns of MMP-2 and MMP-9 in the CSF and cerebellum of dogs with subacute distemper leukoencephalitis.
Dengue
Relationship between MMP Expression and Virulence of Dengue Virus Type-2 in Infected Mosquito and Mammalian Cells.
Dengue
Severity of Plasma Leakage Is Associated With High Levels of Interferon ?-Inducible Protein 10, Hepatocyte Growth Factor, Matrix Metalloproteinase 2 (MMP-2), and MMP-9 During Dengue Virus Infection.
Dental Pulp Necrosis
Decreased levels of matrix metalloproteinase-2 in root-canal exudates during root canal treatment.
Dentigerous Cyst
Correlation between radiographic area and immunolocation of MMP-2 and MMP-9 in unilocular radiographic lesions.
Dentigerous Cyst
Presence of myofibroblasts and matrix metalloproteinase 2 in radicular cysts, dentigerous cysts, and keratocystic odontogenic tumors: a comparative immunohistochemical study.
Dermatitis
Expression of matrix metalloproteinases (MMP-2, MMP-3, and MMP-9) and fibronectin in lichen planus.
Dermatitis
Inflammation in stasis dermatitis upregulates MMP-1, MMP-2 and MMP-13 expression.
Dermatitis, Atopic
Increased Expression of Gelatinase and Caspase Activities in the Skin of NC/Tnd Mice: A Model for Atopic Dermatitis.
Dermatitis, Contact
Analysis of skin patch test results and metalloproteinase-2 levels in a patient with contact dermatitis.
Dermatitis, Contact
Collagen of chronically inflamed skin is over-modified and upregulates secretion of matrix metalloproteinase 2 and matrix-degrading enzymes by endothelial cells and fibroblasts.
Dermatitis, Phototoxic
Protective effect of chromene isolated from Sargassum horneri against UV-A-induced damage in skin dermal fibroblasts.
Dermatofibrosarcoma
Expression of MMP-2, MMP-9 and MMP-11 in dermatofibroma and dermatofibrosarcoma protuberans.
Dermatomyositis
Expression of matrix metalloproteinases in the muscle of patients with inflammatory myopathies.
Diabetes Mellitus
A feasible tool to detect mRNA expression of matrix metalloproteinases and their tissue inhibitors in human Tenon's capsule.
Diabetes Mellitus
Anti-apoptotic activity of human matrix Metalloproteinase-2 attenuates diabetes mellitus.
Diabetes Mellitus
Carotid thickness and atherosclerotic plaque stability, serum inflammation, serum MMP-2 and MMP-9 were associated with acute cerebral infarction.
Diabetes Mellitus
Changes in Activity of Matrix Metalloproteinases and Serum Concentrations of Proinsulin and C-Peptide Depending on the Compensation Stage of Type 2 Diabetes Mellitus.
Diabetes Mellitus
Circulating matrix metalloproteinase-2 is associated with cystatin C level, posttransplant duration, and diabetes mellitus in kidney transplant recipients.
Diabetes Mellitus
Circulating matrix metalloproteinases and their endogenous inhibitors in patients with erectile dysfunction.
Diabetes Mellitus
Effect of Non-Surgical Periodontal Therapy on CRP, Oxidative Stress, MMP-9 and MMP-2 Levels in Patients With Type 2 Diabetes. A Randomized Controlled Study.
Diabetes Mellitus
Effects of N-acetylcysteine on kidney tissue, matrix metalloproteinase-2, irisin and oxidative stress in a diabetes mellitus model.
Diabetes Mellitus
Effects of pioglitazone on expressions of matrix metalloproteinases 2 and 9 in kidneys of diabetic rats.
Diabetes Mellitus
Enhanced expression of two discrete isoforms of matrix metalloproteinase-2 in experimental and human diabetic nephropathy.
Diabetes Mellitus
Evaluation of Urinary Neutrophil Gelatinase Associated Lipocalin and Kidney Injury Molecule-1 as Diagnostic Markers for Early Nephropathy in Patients with Type 2 Diabetes Mellitus.
Diabetes Mellitus
Immunoreactivity of ICAM-1, MMP-2, and Nesfatin-1 in lens epithelial cells of patients with diabetes mellitus with or without diabetic retinopathy.
Diabetes Mellitus
Increased circulatory MMP-2 and MMP-9 levels and activities in patients with type 1 diabetes mellitus.
Diabetes Mellitus
Intraocular matrix metalloproteinase 2 and 9 in patients with diabetes mellitus with and without diabetic retinopathy.
Diabetes Mellitus
Matrix metalloproteinase 2 may be a marker of microangiopathy in children and adolescents with type 1 diabetes mellitus.
Diabetes Mellitus
Matrix Metalloproteinase Gene Polymorphisms and New-Onset Diabetes After Kidney Transplantation in Korean Renal Transplant Subjects.
Diabetes Mellitus
MMP-2 gene polymorphisms in type 2 diabetes mellitus diabetic retinopathy.
Diabetes Mellitus
MMP-2 serum concentrations predict mortality in hemodialysis patients: a 5-year cohort study.
Diabetes Mellitus
Multiple forms of gelatinases/type IV collagenases in saliva and gingival crevicular fluid of periodontitis patients.
Diabetes Mellitus
Periodontal Condition and Immunological Aspects of Individuals Hospitalized in the Intensive Care Unit.
Diabetes Mellitus
Plasma levels of MMP-2, MMP-9 and TIMP-1 are not associated with arterial stiffness in subjects with type 2 diabetes mellitus.
Diabetes Mellitus
Potential role of increased matrix metalloproteinase-2 (MMP2) transcription in impaired adipogenesis in type 2 diabetes mellitus.
Diabetes Mellitus
Renal in situ hybridization studies of extracellular matrix related molecules in type 1 diabetes mellitus.
Diabetes Mellitus
Salivary matrix metalloproteinase (MMP-8) levels and gelatinase (MMP-9) activities in patients with type 2 diabetes mellitus.
Diabetes Mellitus
Serum cystatin C and tubular urinary enzymes as biomarkers of renal dysfunction in type 2 diabetes mellitus.
Diabetes Mellitus
Serum matrix metalloproteinases MMP-2 and MMP-9 and metalloproteinase tissue inhibitors TIMP-1 and TIMP-2 in diabetic nephropathy.
Diabetes Mellitus
The expression of two isoforms of matrix metalloproteinase-2 in aged mouse models of diabetes mellitus and chronic kidney disease.
Diabetes Mellitus
The expressions of inflammatory factors and tissue inhibitor of matrix metalloproteinase-2 in human chronic periodontitis with type 2 diabetes mellitus.
Diabetes Mellitus
The Protective Role of Autophagy in Matrix Metalloproteinase-Mediated Cell Transmigration and Cell Death in High-Glucose-Treated Endothelial Cells.
Diabetes Mellitus
The two isoforms of matrix metalloproteinase- 2 have distinct renal spatial and temporal distributions in murine models of types 1 and 2 diabetes mellitus.
Diabetes Mellitus
Tissue inhibitor of metalloproteinase-2 inhibits T-cell infiltration and preserves pancreatic beta-cell function in an in vitro type 1 diabetes mellitus model.
Diabetes Mellitus
[Change of expression of matrix metalloproteinase-2 in the periodontal tissues of diabetes mellitus rats during orthodontic tooth movement]
Diabetes Mellitus, Experimental
Enhanced cardiac expression of two isoforms of matrix metalloproteinase-2 in experimental diabetes mellitus.
Diabetes Mellitus, Experimental
Renal proteinases and kidney hypertrophy in experimental diabetes.
Diabetes Mellitus, Type 1
Erratum to: Plasma levels of matrix metalloproteinase-2, -3, -10, and tissue inhibitor of metalloproteinase-1 are associated with vascular complications in patients with type 1 diabetes: the EURODIAB Prospective Complications Study.
Diabetes Mellitus, Type 1
Increased circulatory MMP-2 and MMP-9 levels and activities in patients with type 1 diabetes mellitus.
Diabetes Mellitus, Type 1
Kidney injury molecule-1 and neutrophil gelatinase associated lipocalin in normoalbuminuric diabetic children.
Diabetes Mellitus, Type 1
Matrix metalloproteinase -2, -9 and arterial stiffness in children and adolescents: The role of chronic kidney disease, diabetes, and hypertension.
Diabetes Mellitus, Type 1
Matrix metalloproteinase 2 may be a marker of microangiopathy in children and adolescents with type 1 diabetes mellitus.
Diabetes Mellitus, Type 1
Matrix metalloproteinase 2 may be a marker of microangiopathy in children and adolescents with type 1 diabetes.
Diabetes Mellitus, Type 1
Peripheral blood level alterations of TIMP-1, MMP-2 and MMP-9 in patients with type 1 diabetes.
Diabetes Mellitus, Type 1
Plasma levels of matrix metalloproteinase-2, -3, -10, and tissue inhibitor of metalloproteinase-1 are associated with vascular complications in patients with type 1 diabetes: the EURODIAB Prospective Complications Study.
Diabetes Mellitus, Type 1
Renal in situ hybridization studies of extracellular matrix related molecules in type 1 diabetes mellitus.
Diabetes Mellitus, Type 1
The skin remodeling in type 1 diabetes and insulin resistance animal models.
Diabetes Mellitus, Type 1
Tissue inhibitor of metalloproteinase-2 inhibits T-cell infiltration and preserves pancreatic beta-cell function in an in vitro type 1 diabetes mellitus model.
Diabetes Mellitus, Type 1
[Metalloproteinases MMP-2 and MMP-9 and their inhibitors TIMP-1 and TIMP-2 levels in children and adolescents with type 1 diabetes.]
Diabetes Mellitus, Type 2
Association of matrix metalloproteinase-2 gene polymorphisms with susceptibility to type 2 diabetes: A case control study.
Diabetes Mellitus, Type 2
Changes in Activity of Matrix Metalloproteinases and Serum Concentrations of Proinsulin and C-Peptide Depending on the Compensation Stage of Type 2 Diabetes Mellitus.
Diabetes Mellitus, Type 2
Do different bariatric surgical procedures influence plasma levels of matrix metalloproteinase-2, -7, and -9 among patients with type 2 diabetes mellitus?
Diabetes Mellitus, Type 2
Down-regulation of glomerular matrix metalloproteinase-2 gene in human NIDDM.
Diabetes Mellitus, Type 2
Effect of Non-Surgical Periodontal Therapy on CRP, Oxidative Stress, MMP-9 and MMP-2 Levels in Patients With Type 2 Diabetes. A Randomized Controlled Study.
Diabetes Mellitus, Type 2
Evaluation of Urinary Neutrophil Gelatinase Associated Lipocalin and Kidney Injury Molecule-1 as Diagnostic Markers for Early Nephropathy in Patients with Type 2 Diabetes Mellitus.
Diabetes Mellitus, Type 2
Matrix Metalloproteinase Gene Polymorphisms and New-Onset Diabetes After Kidney Transplantation in Korean Renal Transplant Subjects.
Diabetes Mellitus, Type 2
Matrix metalloproteinase-2 (MMP-2) gene polymorphism and cardiovascular comorbidity in type 2 diabetes patients.
Diabetes Mellitus, Type 2
MMP-2 gene polymorphisms in type 2 diabetes mellitus diabetic retinopathy.
Diabetes Mellitus, Type 2
Nuclear factor-kappaB induction by visfatin in human vascular endothelial cells: its role in MMP-2/9 production and activation.
Diabetes Mellitus, Type 2
Plasma levels of MMP-2, MMP-9 and TIMP-1 are not associated with arterial stiffness in subjects with type 2 diabetes mellitus.
Diabetes Mellitus, Type 2
Potential role of increased matrix metalloproteinase-2 (MMP2) transcription in impaired adipogenesis in type 2 diabetes mellitus.
Diabetes Mellitus, Type 2
Salivary matrix metalloproteinase (MMP-8) levels and gelatinase (MMP-9) activities in patients with type 2 diabetes mellitus.
Diabetes Mellitus, Type 2
Serum cystatin C and tubular urinary enzymes as biomarkers of renal dysfunction in type 2 diabetes mellitus.
Diabetes Mellitus, Type 2
Serum matrix metalloproteinases MMP-2 and MMP-9 and metalloproteinase tissue inhibitors TIMP-1 and TIMP-2 in diabetic nephropathy.
Diabetes Mellitus, Type 2
The expressions of inflammatory factors and tissue inhibitor of matrix metalloproteinase-2 in human chronic periodontitis with type 2 diabetes mellitus.
Diabetes Mellitus, Type 2
The two isoforms of matrix metalloproteinase- 2 have distinct renal spatial and temporal distributions in murine models of types 1 and 2 diabetes mellitus.
Diabetes, Gestational
Serum levels of matrix metalloproteinases MMP-2 and MMP-9 and their inhibitors in women with glucose intolerance in pregnancy and normal controls.
Diabetic Angiopathies
High glucose enhances MMP-2 production in adventitial fibroblasts via Akt1-dependent NF-kappaB pathway.
Diabetic Angiopathies
Production of type IV collagen and 72-kDa gelatinase by human endothelial cells cultured in high glucose. Effects of a protein kinase C inhibitor, GF 109203X.
Diabetic Angiopathies
[High glucose and tea polyphenols on expression of matrix metalloproteinase-2 and extracellular matrix metalloproteinase inducer in human umbilical vein endothelial cells]
Diabetic Cardiomyopathies
Antioxidant treatment protects diabetic rats from cardiac dysfunction by preserving contractile protein targets of oxidative stress.
Diabetic Cardiomyopathies
Diabetic Cardiomiopathy Progression is Triggered by miR122-5p and Involves Extracellular Matrix: A 5-Year Prospective Study.
Diabetic Cardiomyopathies
Reduced MMP-2 activity contributes to cardiac fibrosis in experimental diabetic cardiomyopathy.
Diabetic Cardiomyopathies
Role of TSPO/VDAC1 Upregulation and Matrix Metalloproteinase-2 Localization in the Dysfunctional Myocardium of Hyperglycaemic Rats.
Diabetic Cardiomyopathies
The role of alpha-lipoic acid supplementation in the prevention of diabetes complications: A comprehensive review of clinical trials.
Diabetic Cardiomyopathies
[Effects of tamoxifen on CD147 glycosylation and MMPs in the diabetic rat myocardium].
Diabetic Foot
Enzymatically active Peptostreptococcus magnus: association with site of infection.
Diabetic Nephropathies
An imbalance between matrix metalloproteinase-2 and tissue inhibitor of matrix metalloproteinase-2 contributes to the development of early diabetic nephropathy.
Diabetic Nephropathies
Association of serum sestrin 2 and betatrophin with serum neutrophil gelatinase associated lipocalin levels in type 2 diabetic patients with diabetic nephropathy.
Diabetic Nephropathies
C-peptide exhibits a late induction effect on matrix metallopeptidase-9 in high glucose-stimulated rat mesangial cells.
Diabetic Nephropathies
Changes of serum advanced glycation end products (AGEs), matrix metalloprotein-2 (MMP-2), and urinary microalbuminuria (mALB) in diabetic nephropathy and their predictive value for heart failure.
Diabetic Nephropathies
Effects of benazepril on renal function and kidney expression of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in diabetic rats.
Diabetic Nephropathies
Effects of pioglitazone on expressions of matrix metalloproteinases 2 and 9 in kidneys of diabetic rats.
Diabetic Nephropathies
Elevated matrix metalloproteinase-2 and -9 in urine, but not in serum, are markers of type 1 diabetic nephropathy.
Diabetic Nephropathies
Enhanced expression of two discrete isoforms of matrix metalloproteinase-2 in experimental and human diabetic nephropathy.
Diabetic Nephropathies
Epigenetic Regulation of the N-Terminal Truncated Isoform of Matrix Metalloproteinase-2 (NTT-MMP-2) and Its Presence in Renal and Cardiac Diseases.
Diabetic Nephropathies
Experimental diabetic nephropathy is accelerated in matrix metalloproteinase-2 knockout mice.
Diabetic Nephropathies
In Diabetic Kidney Disease Urinary Exosomes Better Represent Kidney Specific Protein Alterations Than Whole Urine.
Diabetic Nephropathies
Inhibitory effects of salvianolic acid B on the high glucose-induced mesangial proliferation via NF-kappaB-dependent pathway.
Diabetic Nephropathies
Matrix metalloproteinase-2 (MMP-2) and membrane-type 1 MMP (MT1-MMP) affect the remodeling of glomerulosclerosis in diabetic OLETF rats.
Diabetic Nephropathies
Matrix metalloproteinase-2 and mesangiolysis in diabetic nephropathy.
Diabetic Nephropathies
Minocycline with aspirin: an approach to attenuate diabetic nephropathy in rats.
Diabetic Nephropathies
Pioglitazone Attenuates Cardiac Fibrosis and Hypertrophy in a Rat Model of Diabetic Nephropathy.
Diabetic Nephropathies
Plasma levels of tissue inhibitor of metalloproteinase-1 in patients with type 1 diabetes mellitus associate with early diabetic neuropathy and nephropathy.
Diabetic Nephropathies
PTGER3 and MMP-2 play potential roles in diabetic nephropathy via competing endogenous RNA mechanisms.
Diabetic Nephropathies
Ramipril inhibits AGE-RAGE-induced matrix metalloproteinase-2 activation in experimental diabetic nephropathy.
Diabetic Nephropathies
Renal in situ hybridization studies of extracellular matrix related molecules in type 1 diabetes mellitus.
Diabetic Nephropathies
Serum matrix metalloproteinases MMP-2 and MMP-9 and metalloproteinase tissue inhibitors TIMP-1 and TIMP-2 in diabetic nephropathy.
Diabetic Nephropathies
The role of matrix metalloproteinases 2 in atherosclerosis of patients with chronic kidney disease in type 2 diabetes.
Diabetic Nephropathies
Utility of urinary biomarkers as a diagnostic tool for early diabetic nephropathy in patients with type 2 diabetes mellitus.
Diabetic Nephropathies
[Effects of puerarin on renal function, expressions of MMP-2 and TIMP-2 in diabetic rats]
Diabetic Neuropathies
Matrix metalloproteinase-2 is downregulated in sciatic nerve by streptozotocin induced diabetes and/or treatment with minocycline: Implications for nerve regeneration.
Diabetic Neuropathies
Minocycline with aspirin: a therapeutic approach in the treatment of diabetic neuropathy.
Diabetic Retinopathy
Attenuation of diabetic retinopathy by enhanced inhibition of MMP-2 and MMP-9 using aspirin and minocycline in streptozotocin-diabetic rats.
Diabetic Retinopathy
Circ-ITCH restrains the expression of MMP-2, MMP-9 and TNF-? in diabetic retinopathy by inhibiting miR-22.
Diabetic Retinopathy
Functional links between gelatinase B/matrix metalloproteinase-9 and prominin-1/CD133 in diabetic retinal vasculopathy and neuropathy.
Diabetic Retinopathy
Genetic variations and plasma levels of gelatinase A (matrix metalloproteinase-2) and gelatinase B (matrix metalloproteinase-9) in proliferative diabetic retinopathy.
Diabetic Retinopathy
Immunoreactivity of ICAM-1, MMP-2, and Nesfatin-1 in lens epithelial cells of patients with diabetes mellitus with or without diabetic retinopathy.
Diabetic Retinopathy
Interrelationship between activation of matrix metalloproteinases and mitochondrial dysfunction in the development of diabetic retinopathy.
Diabetic Retinopathy
Intraocular matrix metalloproteinase 2 and 9 in patients with diabetes mellitus with and without diabetic retinopathy.
Diabetic Retinopathy
Matrix metalloproteinase-2 expression and apoptogenic activity in retinal pericytes: implications in diabetic retinopathy.
Diabetic Retinopathy
Matrix metalloproteinase-2 in the development of diabetic retinopathy and mitochondrial dysfunction.
Diabetic Retinopathy
Matrix metalloproteinases in diabetic retinopathy: potential role of MMP-9.
Diabetic Retinopathy
MMP-2 gene polymorphisms in type 2 diabetes mellitus diabetic retinopathy.
Diabetic Retinopathy
Novel Role of Mitochondrial Matrix Metalloproteinase-2 in the Development of Diabetic Retinopathy.
Diabetic Retinopathy
Oxidative stress and the development of diabetic retinopathy: contributory role of matrix metalloproteinase-2.
Diabetic Retinopathy
Production and activation of matrix metalloproteinase-2 in proliferative diabetic retinopathy.
Diabetic Retinopathy
Regulation of Matrix Metalloproteinase in the Pathogenesis of Diabetic Retinopathy.
Diabetic Retinopathy
Role of matrix metalloproteinase-2 and -9 in the development of diabetic retinopathy.
Diabetic Retinopathy
VEGF Secreted by Hypoxic Muller Cells Induces MMP-2 Expression and Activity in Endothelial Cells to Promote Retinal Neovascularization in Proliferative Diabetic Retinopathy.
Distemper
Phase-dependent expression of matrix metalloproteinases and their inhibitors in demyelinating canine distemper encephalitis.
Distemper
Zymographic patterns of MMP-2 and MMP-9 in the CSF and cerebellum of dogs with subacute distemper leukoencephalitis.
Diverticular Diseases
Increased concentration of tissue-degrading matrix metalloproteinases and their inhibitor in complicated diverticular disease.
Diverticulitis
Comparative analysis of the expression of metalloproteases and their inhibitors in resected crohn's disease and complicated diverticular disease.
Diverticulum
Up-regulation of collagen and tissue inhibitors of matrix metalloproteinase in colonic diverticular disease.
Down Syndrome
Analysis of matrix metalloproteinase (MMP-8 and MMP-2) activity in gingival crevicular fluid from children with Down's syndrome.
Down Syndrome
Enhancement of matrix metalloproteinase (MMP)-2 activity in gingival tissue and cultured fibroblasts from Down's syndrome patients.
Dry Eye Syndromes
High Levels of 17?-Estradiol Are Associated with Increased Matrix Metalloproteinase-2 and Metalloproteinase-9 Activity in Tears of Postmenopausal Women with Dry Eye.
Duodenal Ulcer
Inappropriate Angiogenic Response as a Novel Mechanism of Duodenal Ulceration and Impaired Healing.
Duodenal Ulcer
[Role of Allelic Genes of Matrix Metalloproteinases and Their Tissue Inhibitors in the Peptic Ulcer Disease Development].
Dupuytren Contracture
Expression of MMP-2, TIMP-2, TGF-?1, and Decorin in Dupuytren's Contracture.
Dupuytren Contracture
Matrix metalloproteinases and tissue inhibitors of metalloproteinases in sera and tissue of patients with Dupuytren's disease.
Dupuytren Contracture
MMP-14 and MMP-2 are key metalloproteases in Dupuytren's disease fibroblast-mediated contraction.
Dwarfism
Comparative Serum Analyses Identify Cytokines and Hormones Commonly Dysregulated as Well as Implicated in Promoting Osteolysis in MMP-2-Deficient Mice and Children.
Dyslipidemias
Evaluation of metalloproteinase 2 and 9 levels and their inhibitors in combined dyslipidemia.
Dyslipidemias
Rice bran protein hydrolysates reduce arterial stiffening, vascular remodeling and oxidative stress in rats fed a high-carbohydrate and high-fat diet.
Dyslipidemias
The effect of obesity and tobacco smoke exposure on inflammatory mediators and matrix metalloproteinases in rat model.
Dysplastic Nevus Syndrome
Coordinate expression of membrane type-matrix metalloproteinases-2 and 3 (MT2-MMP and MT3-MMP) and matrix metalloproteinase-2 (MMP-2) in primary and metastatic melanoma cells.
Dysplastic Nevus Syndrome
Immunohistochemical expression of vascular endothelial growth factor, matrix metalloproteinase 2, and matrix metalloproteinase 9 in cutaneous melanocytic lesions.
Dysplastic Nevus Syndrome
Matrix metalloproteinases MMP-1, MMP-2, and MMP-13 are overexpressed in primary nodular melanoma.
Ear Neoplasms
[Expression of matrix metalloproteinasa-2,9 in cholesteatoma and middle ear cancer]
Embolic Stroke
Matrix metalloproteinase expression after human cardioembolic stroke: temporal profile and relation to neurological impairment.
Embolic Stroke
Matrix metalloproteinase expression is related to hemorrhagic transformation after cardioembolic stroke.
Embolic Stroke
MMP-2 concentrations in stroke according to etiology: Adjusting for enzyme degradation in stored deep-frozen serum and other methodological pitfalls.
Empyema
Matrix metalloproteinase levels in the differentiation of parapneumonic pleural effusions.
Encephalitis
Circulating levels of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases during Japanese encephalitis virus infection.
Encephalitis
Increased matrix metalloproteinases in cerebrospinal fluids of patients with major depressive disorder and schizophrenia.
Encephalitis
Matrix metalloproteinase-2 and -9 lead to fibronectin degradation in astroglia infected with Toxoplasma gondii.
Encephalitis
Phase-dependent expression of matrix metalloproteinases and their inhibitors in demyelinating canine distemper encephalitis.
Encephalitis, Viral
Expression of MMP-2 and TIMP-1 in cerebrospinal fluid and the correlation with dynamic changes of serum PCT in neonatal purulent meningitis.
Encephalomyelitis
Distinct roles for matrix metalloproteinase-2 and alpha4 integrin in autoimmune T cell extravasation and residency in brain parenchyma during experimental autoimmune encephalomyelitis.
Encephalomyelitis
Gelatinase B/matrix metalloproteinase-9 is a phase-specific effector molecule, independent from Fas, in experimental autoimmune encephalomyelitis.
Encephalomyelitis
Imaging matrix metalloproteinase activity in multiple sclerosis as a specific marker of leukocyte penetration of the blood-brain barrier.
Encephalomyelitis
Magnetic brain stimulation upregulates adhesion and prevents Eae: MMP-2, ICAM-1, and VCAM-1 in the choroid plexus as a target.
Encephalomyelitis
Minocycline suppresses experimental autoimmune encephalomyelitis by increasing tissue inhibitors of metalloproteinases.
Encephalomyelitis
MMP-2 null mice exhibit an early onset and severe experimental autoimmune encephalomyelitis due to an increase in MMP-9 expression and activity.
Encephalomyelitis
MMP-2, VCAM-1 and NCAM-1 expression in the brain of rats with experimental autoimmune encephalomyelitis as a trigger mechanism for synaptic plasticity and pathology.
Encephalomyelitis
On the structure and functions of gelatinase B/matrix metalloproteinase-9 in neuroinflammation.
Encephalomyelitis
Resistance of young gelatinase B-deficient mice to experimental autoimmune encephalomyelitis and necrotizing tail lesions.
Encephalomyelitis
The gelatinases, MMP-2 and MMP-9, as fine tuners of neuroinflammatory processes.
Encephalomyelitis
The interrelationship of alpha4 integrin and matrix metalloproteinase-2 in the pathogenesis of experimental autoimmune encephalomyelitis.
Encephalomyelitis
Treatment of experimental autoimmune encephalomyelitis with a neurotropic alphavirus vector expressing tissue inhibitor of metalloproteinase-2.
Encephalomyelitis, Autoimmune, Experimental
Distinct roles for matrix metalloproteinase-2 and alpha4 integrin in autoimmune T cell extravasation and residency in brain parenchyma during experimental autoimmune encephalomyelitis.
Encephalomyelitis, Autoimmune, Experimental
Gelatinase B/matrix metalloproteinase-9 is a phase-specific effector molecule, independent from Fas, in experimental autoimmune encephalomyelitis.
Encephalomyelitis, Autoimmune, Experimental
Imaging matrix metalloproteinase activity in multiple sclerosis as a specific marker of leukocyte penetration of the blood-brain barrier.
Encephalomyelitis, Autoimmune, Experimental
Magnetic brain stimulation upregulates adhesion and prevents Eae: MMP-2, ICAM-1, and VCAM-1 in the choroid plexus as a target.
Encephalomyelitis, Autoimmune, Experimental
Matrix metalloproteinase-9 (gelatinase B) is selectively elevated in CSF during relapses and stable phases of multiple sclerosis.
Encephalomyelitis, Autoimmune, Experimental
Minocycline suppresses experimental autoimmune encephalomyelitis by increasing tissue inhibitors of metalloproteinases.
Encephalomyelitis, Autoimmune, Experimental
MMP-2 null mice exhibit an early onset and severe experimental autoimmune encephalomyelitis due to an increase in MMP-9 expression and activity.
Encephalomyelitis, Autoimmune, Experimental
MMP-2, VCAM-1 and NCAM-1 expression in the brain of rats with experimental autoimmune encephalomyelitis as a trigger mechanism for synaptic plasticity and pathology.
Encephalomyelitis, Autoimmune, Experimental
Pathological findings in rats with experimental allergic encephalomyelitis.
Encephalomyelitis, Autoimmune, Experimental
Resistance of young gelatinase B-deficient mice to experimental autoimmune encephalomyelitis and necrotizing tail lesions.
Encephalomyelitis, Autoimmune, Experimental
The gelatinases, MMP-2 and MMP-9, as fine tuners of neuroinflammatory processes.
Encephalomyelitis, Autoimmune, Experimental
The interrelationship of alpha4 integrin and matrix metalloproteinase-2 in the pathogenesis of experimental autoimmune encephalomyelitis.
Encephalomyelitis, Autoimmune, Experimental
Treatment of experimental autoimmune encephalomyelitis with a neurotropic alphavirus vector expressing tissue inhibitor of metalloproteinase-2.
Endocarditis
Characterization of Enterococcus faecium isolates and first report of vanB phenotype-vanA genotype incongruence in the Middle East.
Endocarditis
Comparison of the incidence of virulence determinants and antibiotic resistance between Enterococcus faecium strains of dairy, animal and clinical origin.
Endocarditis
Enterocin AS-48RJ: a variant of enterocin AS-48 chromosomally encoded by Enterococcus faecium RJ16 isolated from food.
Endocarditis
Enterococcal virulence determinants may be involved in resistance to clinical therapy.
Endocarditis
Evaluation of Enterococcus mundtii ST4SA and Lactobacillus plantarum 423 as probiotics by using a gastro-intestinal model with infant milk formulations as substrate.
Endocarditis
Fsr-independent production of protease(s) may explain the lack of attenuation of an Enterococcus faecalis fsr mutant versus a gelE-sprE mutant in induction of endocarditis.
Endocarditis
Gelatinase contributes to the pathogenesis of endocarditis caused by Enterococcus faecalis.
Endocarditis
Gelatinase is important for translocation of Enterococcus faecalis across polarized human enterocyte-like T84 cells.
Endocarditis
Genotypic and phenotypic diversity in Enterococcus faecalis: is agar invasion a pathogenicity score?
Endocarditis
Incidence of hemolysin, gelatinase, and aggregation substance among enterococci isolated from patients with endocarditis and other infections and from feces of hospitalized and community-based persons.
Endocarditis
Incidence of virulence factors in enterococci from raw and fermented meat and biofilm forming capacity at 25°C and 37°C.
Endocarditis
IS256 abolishes gelatinase activity and biofilm formation in a mutant of the nosocomial pathogen Enterococcus faecalis V583.
Endocarditis
Prevalence of enterococcus species and their virulence genes in fresh water prior to and after storm events.
Endocarditis
Survey for virulence determinants among Enterococcus faecalis isolated from different sources.
Endocarditis
The Enterococcus faecalis fsr two-component system controls biofilm development through production of gelatinase.
Endocarditis
Virulence, phenotype and genotype characteristics of endodontic Enterococcus spp.
Endocarditis
[The study of activity of matrix metalloproteinases abd reactants of inflammation in patients with endocarditis.]
Endoleak
Correlation of Baseline Plasma and Inguinal Connective Tissue Metalloproteinases and Their Inhibitors With Late High-Pressure Endoleak After Endovascular Aneurysm Repair: Long-term Results.
Endometrial Hyperplasia
Enhanced expressions of matrix metalloproteinase (MMP)-2 and -9 and vascular endothelial growth factors (VEGF) and increased microvascular density in the endometrial hyperplasia of women with anovulatory dysfunctional uterine bleeding.
Endometrial Hyperplasia
Matrix Metalloproteinases and Their Tissue Inhibitors in Blood Serum of Patients with Endometrial Cancer: Clinical and Morphological Correlations.
Endometrial Hyperplasia
Mechanisms of matrix metalloproteinase-2 (mmp-2) transcriptional repression by progesterone in jar choriocarcinoma cells.
Endometrial Neoplasms
Angiogenesis extent and expression of matrix metalloproteinase-2 and -9 correlate with upgrading and myometrial invasion in endometrial carcinoma.
Endometrial Neoplasms
Characterization of extracellular matrix-degrading proteinase and its inhibitor in gynecologic cancer tissues with clinically different metastatic form.
Endometrial Neoplasms
Clinical significance of matrix metalloproteinase-2 in endometrial cancer: A systematic review and meta-analysis.
Endometrial Neoplasms
Combination of strong MMP-2 and weak TIMP-2 immunostainings is a significant prognostic factor in endometrial carcinoma.
Endometrial Neoplasms
Corticotropin-releasing hormone enhances the invasiveness and migration of Ishikawa cells, possibly by increasing matrix metalloproteinase-2 and matrix metalloproteinase-9.
Endometrial Neoplasms
Detection of endometrial cancer by determination of matrix metalloproteinases in the uterine cavity.
Endometrial Neoplasms
Different pattern of zymography between human gynecologic normal and malignant tissues.
Endometrial Neoplasms
Differential expression of MMP-2, MMP-9 and PCNA in endometriosis and endometrial carcinoma.
Endometrial Neoplasms
Effects of curcumin on the role of MMP-2 in endometrial cancer cell proliferation and invasion.
Endometrial Neoplasms
Effects of hepatocyte growth factor on the expression of matrix metalloproteinases and their tissue inhibitors during the endometrial cancer invasion in a three-dimensional coculture.
Endometrial Neoplasms
ERM/ETV5 up-regulation plays a role during myometrial infiltration through matrix metalloproteinase-2 activation in endometrial cancer.
Endometrial Neoplasms
Expression of gelatinase (MMP-2 and MMP-9) and cyclooxygenase-2 (COX-2) in endometrial carcinoma.
Endometrial Neoplasms
Expression of matrix metalloproteinase-2 and survivin in endometrioid and nonendometrioid endometrial cancers and clinicopathologic significance.
Endometrial Neoplasms
Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinase in uterine endometrial carcinoma and a correlation between expression of matrix metalloproteinase-7 and prognosis.
Endometrial Neoplasms
Extracellular matrix metalloproteinase inducer and matrix metalloproteinase-2 overexpression is associated with loss of hormone receptor expression and poor prognosis in endometrial cancer.
Endometrial Neoplasms
Gelatinases A and B (MMP-2 and MMP-9) in endometrial cancer-MMP-9 correlates to the grade and the stage.
Endometrial Neoplasms
IL-37b?1-45 suppresses the migration and invasion of endometrial cancer cells by targeting the Rac1/NF-?B/MMP2 signal pathway.
Endometrial Neoplasms
Immunohistochemical detection of matrix metalloproteinases (MMP) 1 and 2, and tissue inhibitor of metalloproteinase 2 (TIMP 2) in stage I and II endometrial cancer.
Endometrial Neoplasms
Immunohistochemical expression of hormone receptors, Ki-67, endoglin (CD105), claudins 3 and 4, MMP-2 and -9 in endometrial polyps and endometrial cancer type I.
Endometrial Neoplasms
Immunohistochemical expression of MMP-2, MMP-9 and COX-2 in Stage IA malignant polyps of the endometrium.
Endometrial Neoplasms
Inhibitory effect of ginsenoside-Rb2 on invasiveness of uterine endometrial cancer cells to the basement membrane.
Endometrial Neoplasms
Malignant cell-specific gelatinase activity in human endometrial carcinoma.
Endometrial Neoplasms
Matrix metalloproteinase-7 (MMP-7) polymorphism is a risk factor for endometrial cancer susceptibility.
Endometrial Neoplasms
Matrix Metalloproteinases and Their Tissue Inhibitors in Blood Serum of Patients with Endometrial Cancer: Clinical and Morphological Correlations.
Endometrial Neoplasms
Metalloproteinase-2, -7 and -9 and tissue inhibitor of metalloproteinase-1 and -2 expression in normal, hyperplastic and neoplastic endometrium: a clinical-pathological correlation study.
Endometrial Neoplasms
miR-124 functions as a tumor suppressor in the endometrial carcinoma cell line HEC-1B partly by suppressing STAT3.
Endometrial Neoplasms
MMP-2 expression associates with CA 125 and clinical course in endometrial carcinoma.
Endometrial Neoplasms
Overexpression of BP1, an isoform of Homeobox Gene DLX4, promotes cell proliferation, migration and predicts poor prognosis in endometrial cancer.
Endometrial Neoplasms
p21-activated kinase 4 regulation of endometrial cancer cell migration and invasion involves the ERK1/2 pathway mediated MMP-2 secretion.
Endometrial Neoplasms
Presence of active gelatinases in endometrial carcinoma and correlation of matrix metalloproteinase expression with increasing tumor grade and invasion.
Endometrial Neoplasms
Selective gene transfer to endometrial cancer cells by a polymer against matrix metalloproteinase 2 (MMP-2).
Endometrial Neoplasms
The association of transforming growth factor-beta 1 with myometrial invasion of endometrial carcinomas through effects on matrix metalloproteinase.
Endometrial Neoplasms
The influence of vascular endothelial growth factor-A and matrix metalloproteinase-2 and -9 in angiogenesis, metastasis, and prognosis of endometrial cancer.
Endometrial Neoplasms
The relationships between the immunoexpression of KAI1, MMP-2, MMP-9 and steroid receptors expression in endometrial cancer.
Endometrial Neoplasms
[Activity of matrix metalloproteinases -2 and -9 (MMP-2 and MMP-9) and content of their tissue inhibitors in endometrial cancer--a preliminary study]
Endometrial Neoplasms
[Expression of matrix metalloproteinase-2, 9 and it's tissue inhibitor-1, 2 in endometrial carcinoma]
Endometrial Neoplasms
[Matrix metalloproteinases and their tissue inhibitors in malignancies of the female genital tract]
Endometrial Neoplasms
[Methylation of matrix metalloproteinases-2 promoter in endometrial cancer invasion].
Endometrial Neoplasms
[Progesterone receptor's profile and the effect of the hormone and its derivatives on invasiveness and MMP2 secretion in endometrial carcinoma cell lines]
Endometrial Neoplasms
[Prognostic value of serum MMP-2 level in uterine cancer affected women]
Endometriosis
15-Epi-lipoxin A(4) inhibits the progression of endometriosis in a murine model.
Endometriosis
Angiogenesis extent and expression of matrix metalloproteinase-2 and -9 agree with progression of ovarian endometriomas.
Endometriosis
Association between matrix metalloproteinase-2 and matrix metalloproteinase-9 polymorphisms and endometriosis: A systematic review and meta-analysis.
Endometriosis
Association Between MMP-2 and TIMP-2 Gene Polymorphisms and Advanced-Stage Endometriosis in Korean Women.
Endometriosis
Association of polymorphisms of the MMP-2 and TIMP-2 genes with the risk of endometriosis in North Chinese women.
Endometriosis
Associations between various possible promoter polymorphisms of MMPs genes and endometriosis risk: a meta-analysis.
Endometriosis
Autocrine Production of Interleukin-34 Promotes the Development of Endometriosis through CSF1R/JAK3/STAT6 signaling.
Endometriosis
CAPN 7 promotes the migration and invasion of human endometrial stromal cell by regulating matrix metalloproteinase 2 activity.
Endometriosis
Change profiles in matrix metalloproteinase-2 and -9 in induced endometriosis in mice.
Endometriosis
Clinical significance of matrix metalloproteinase-2 in endometrial cancer: A systematic review and meta-analysis.
Endometriosis
Differential expression of MMP-2, MMP-9 and PCNA in endometriosis and endometrial carcinoma.
Endometriosis
Differential regulation of matrix metalloproteinase-3 gene expression in endometriotic lesions compared with endometrium.
Endometriosis
Disturbed progesterone signalling in an advanced preclinical model of endometriosis.
Endometriosis
Doxycycline reduces MMP-2 activity and inhibits invasion of 12Z epithelial endometriotic cells as well as MMP-2 and -9 activity in primary endometriotic stromal cells in vitro.
Endometriosis
Effect of matrix metalloproteinase promoter polymorphisms on endometriosis and adenomyosis risk: evidence from a meta-analysis.
Endometriosis
Effect of traditional Chinese medicine (Xiaochaihu Tang) on the expression of MMP-2 and MMP-9 in rats with endometriosis.
Endometriosis
Effects of estrogen and progestin on expression of MMP-2 and TIMP-2 in a nude mouse model of endometriosis.
Endometriosis
Effects of Yiweining recipe on expressions of metalloproteinase-2 and cyclooxygenase-2 mRNAs in ectopic endometrium of rats with endometriosis.
Endometriosis
Endometriotic epithelial cells induce MMPs expression in endometrial stromal cells via an NFkappaB-dependent pathway.
Endometriosis
Eutopic endometrium and peritoneal, ovarian and bowel endometriotic tissues express a different profile of matrix metalloproteinases-2, -3 and -11, and of tissue inhibitor metalloproteinases-1 and -2.
Endometriosis
Evidence for an increased release of proteolytic activity by the eutopic endometrial tissue in women with endometriosis and for involvement of matrix metalloproteinase-9.
Endometriosis
Expression and significance of autophagy genes LC3, Beclin1 and MMP-2 in endometriosis.
Endometriosis
Expression and Significance of Matrix Metalloproteinase-2 and Matrix Metalloproteinas-9 in Endometriosis.
Endometriosis
Expression of CD44s, vascular endothelial growth factor, matrix metalloproteinase-2 and Ki-67 in peritoneal, rectovaginal and ovarian endometriosis.
Endometriosis
Expression of metalloproteinase-9 in ectopic endometrium in women with endometriosis.
Endometriosis
Gelatinase A (MM-2), gelatinase B (MMP-9) and their inhibitors (TIMP 1, TIMP-2) in serum of women with endometriosis: Significant correlation between MMP-2, MMP-9 and their inhibitors without difference in levels of matrix metalloproteinases and tissue inhibitors of metalloproteinases in relation to the severity of endometriosis.
Endometriosis
Gene expression of adhesion molecules and matrix metalloproteinases in endometriosis.
Endometriosis
Genetic polymorphisms and endometriosis: contribution of genes that regulate vascular function and tissue remodeling.
Endometriosis
Human Wharton's jelly stem cells inhibit endometriosis through apoptosis induction.
Endometriosis
Increased Circulating MMP-2 Levels in Infertile Patients With Moderate and Severe Pelvic Endometriosis.
Endometriosis
Investigating the association of matrix metalloproteinase-2 gene variants with endometriosis in an Iranian population.
Endometriosis
Matrix metalloproteinase 2 is associated with changes in steroid hormones in the sera and peritoneal fluid of patients with endometriosis.
Endometriosis
Matrix metalloproteinase messenger RNA expression in human endometriosis grafts cultured on a chicken chorioallantoic membrane.
Endometriosis
Matrix metalloproteinase-2 (MMP-2), MMP-9, tissue inhibitor of matrix metalloproteinases (TIMP-1) and transforming growth factor-?2 (TGF-?2) expression in eutopic endometrium of women with peritoneal endometriosis.
Endometriosis
Matrix metalloproteinase-2, membranous type 1 matrix metalloproteinase, and tissue inhibitor of metalloproteinase-2 expression in ectopic and eutopic endometrium.
Endometriosis
Matrix metalloproteinases 2 and 9, E-cadherin, and beta-catenin expression in endometriosis, low-grade endometrial carcinoma and non-neoplastic eutopic endometrium.
Endometriosis
Matrix metalloproteinases are elevated in the urine of patients with endometriosis.
Endometriosis
Mechanisms of matrix metalloproteinase-2 (mmp-2) transcriptional repression by progesterone in jar choriocarcinoma cells.
Endometriosis
Mechanisms regulating invasiveness and growth of endometriosis lesions in rat experimental model and in humans.
Endometriosis
mRNA expression and DNA methylation level of the MMP-2 gene in peritoneal endometriosis.
Endometriosis
Polymorphisms in MMP-2 and MMP-9 promoter regions are associated with endometriosis.
Endometriosis
Regulation of Matrix Metalloproteinase-2 Activity by COX-2-PGE2-pAKT Axis Promotes Angiogenesis in Endometriosis.
Endometriosis
SMURF1-mediated ubiquitylation of SHP-1 promotes cell proliferation and invasion of endometrial stromal cells in endometriosis.
Endometriosis
Suppression of matrix metalloproteinase-9 by prostaglandin E(2) in peritoneal macrophage is associated with severity of endometriosis.
Endometriosis
Survivin, MMP-2, MT1-MMP, and TIMP-2: their impact on survival, implantation, and proliferation of endometriotic tissues.
Endometriosis
The Effect of Imbalanced Progesterone Receptor-A/-B Ratio on Gelatinase Expressions in Endometriosis.
Endometriosis
The modulating effects of Resveratrol on the expression of MMP-2 and MMP-9 in endometriosis women: a randomized exploratory trial.
Endometriosis
TNFRp55 deficiency promotes the development of ectopic endometriotic-like lesions in mice.
Endometriosis
Ureaplasma Urealyticum Infection Contributes to the Development of Pelvic Endometriosis Through Toll-Like Receptor 2.
Endometriosis
Vascular endothelial growth factor and matrix metalloproteinase-2 expedite formation of endometriosis in the early stage ICR mouse model.
Endometriosis
[Effect of progesterone on the secretion of matrix metalloproteinase-2 and matrix metalloproteinase-9 in human ectopic endometrial stromal cells]
Endometriosis
[Effect of the combination of bushen xuguan recipe and ruanjian huayu recipe on the MMP-2 expression in endometriosis rats].
Endometriosis
[Effects of acupuncture combined with medicine on expression of matrix metalloproteinase-2 in the rat of endometriosis]
Endometriosis
[Expression of matrix metalloproteinase and tissue inhibitor of metalloproteinase in adenomyosis]
Endometriosis
[Inhibitory effect on estrogen production and its influence on invasive ability of human endometrial cells of endometriosis by medicated serum of SLW]
Endometriosis
[Molecular biological features of ectopic and eutopic endometrium in genital endometriosis].
Endometriosis
[Study on the association of SNPs of MMP-2 and TIMP-2 genes with the risk of endometriosis and adenomyosis]
Endophthalmitis
Contribution of gelatinase, serine protease, and fsr to the pathogenesis of Enterococcus faecalis endophthalmitis.
Endotoxemia
ELR-CXC chemokine receptor antagonism targets inflammatory responses at multiple levels.
Endotoxemia
Endotoxemia shifts neutrophils with TIMP-free gelatinase B/ MMP-9 from bone marrow to periphery and induces systematic upregulation of TIMP-1.
Endotoxemia
Matrix metalloproteinase activities are altered in the heart and plasma during endotoxemia.
Endotoxemia
Roles of MMP-2/-9 in cardiac dysfunction during early multiple organ failure in an ovine animal model.
Endotoxemia
Small interfering RNA targeting focal adhesion kinase prevents cardiac dysfunction in endotoxemia.
Enteritis
Role of matrix metalloproteinases in the pathogenesis of childhood gastroenteritis.
Ependymoma
The effects of exogenous growth factors on matrix metalloproteinase secretion by human brain tumour cells.
Epidermal Cyst
Gelatinase B in chronic synovitis: immunolocalization with a monoclonal antibody.
Epidermolysis Bullosa Dystrophica
Inhibition of collagen degradative enzymes by retinoic acid in vitro.
Epidermolysis Bullosa Dystrophica
Skin expression of metalloproteinases and tissue inhibitor of metalloproteinases in sibling patients with recessive dystrophic epidermolysis and intrafamilial phenotypic variation.
Epidermolysis Bullosa Simplex
Epidermolysis bullosa simplex: expression of gelatinase activity in cultured human skin fibroblasts.
Epidermolysis Bullosa Simplex
Gelatinase expression in generalized epidermolysis bullosa simplex fibroblasts.
Epilepsy
Chronic Intermittent Ethanol Exposure Induces Upregulation of Matrix Metalloproteinase-9 in the Rat Medial Prefrontal Cortex and Hippocampus.
Epilepsy
Design and synthesis of selective and blood-brain barrier-permeable hydroxamate-based gelatinase inhibitors.
Epilepsy
Imbalance of matrix metalloproteinase-9 and matrix metalloproteinase tissue inhibitor-1 may contribute to hemorrhage in cerebellar arteriovenous malformations.
Epilepsy
Increased Expression of Matrix Metalloproteinase-9 in Patients with Temporal Lobe Epilepsy.
Epilepsy
Matrix metalloproteinase (MMP)-2 gene polymorphisms affect circulating MMP-2 levels in patients with migraine with aura.
Epilepsy
Matrix metalloproteinases contribute to neuronal dysfunction in animal models of drug dependence, Alzheimer's disease, and epilepsy.
Epilepsy
Recruited leukocytes and local synthesis account for increased matrix metalloproteinase-9 activity in cerebrospinal fluid of dogs with central nervous system neoplasm.
Epilepsy
Serum matrix metalloproteinase-2: A potential biomarker for diagnosis of epilepsy.
Epilepsy, Temporal Lobe
Gelatinase Biosensor Reports Cellular Remodeling During Epileptogenesis.
Epilepsy, Temporal Lobe
Increased Expression of Matrix Metalloproteinase-9 in Patients with Temporal Lobe Epilepsy.
Epiretinal Membrane
Interleukin-1-beta changes the expression of metalloproteinases in the vitreous humor and induces membrane formation in eyes containing preexisting retinal holes.
Epiretinal Membrane
Predominance of MMP-1 and MMP-2 in epiretinal and subretinal membranes of proliferative vitreoretinopathy.
Epiretinal Membrane
Vitreous TIMP-1 levels associate with neovascularization and TGF-?2 levels but not with fibrosis in the clinical course of proliferative diabetic retinopathy.
Erythema Nodosum
Matrix metalloproteinase-2, -9, -12, and tissue inhibitor of metalloproteinase 2 gene polymorphisms and cutaneous expressions in patients with Behçet's disease.
Escherichia coli Infections
Activation of human progelatinase A/promatrix metalloproteinase 2 by Escherichia coli-derived serine proteinase.
Esophageal Achalasia
Gelatinase B/Matrix Metalloproteinase-9 as Innate Immune Effector Molecule in Achalasia.
Esophageal Neoplasms
Androgen receptor promotes esophageal cancer cell migration and proliferation via matrix metalloproteinase 2.
Esophageal Neoplasms
Expression of decorin in esophageal cancer in relation to the expression of three isoforms of transforming growth factor-beta (TGF-beta1, -beta2, and -beta3) and matrix metalloproteinase-2 activity.
Esophageal Neoplasms
Functional haplotypes in the promoter of matrix metalloproteinase-2 predict risk of the occurrence and metastasis of esophageal cancer.
Esophageal Neoplasms
MiR-196a binding-site SNP regulates RAP1A expression contributing to esophageal squamous cell carcinoma risk and metastasis.
Esophageal Neoplasms
MMP-2 and DcR3 expression in esophageal cancer tissue and correlation with patient survival.
Esophageal Neoplasms
Prognostic significance of stromelysin-3 and tissue inhibitor of matrix metalloproteinase-2 in esophageal cancer.
Esophageal Neoplasms
Serum matrix metalloproteinase 2 and tissue inhibitor of matrix metalloproteinases 2 in esophageal cancer patients.
Esophageal Neoplasms
The expression and clinical significance of metastasis suppressor gene and matrix metalloproteinase-2 in esophageal squamous cell of carcinoma.
Esophageal Neoplasms
[Correlation between expression of matrix metalloproteinase-2 and angiogenesis in esophageal carcinoma]
Esophageal Neoplasms
[Genetic polymorphisms in STK15 and MMP-2 associated susceptibility to esophageal cancer in Mongolian population]
Esophageal Squamous Cell Carcinoma
ALDH1A1 defines invasive cancer stem-like cells and predicts poor prognosis in patients with esophageal squamous cell carcinoma.
Esophageal Squamous Cell Carcinoma
Aurora-A modulates MMP-2 expression via AKT/NF-?B pathway in esophageal squamous cell carcinoma cells.
Esophageal Squamous Cell Carcinoma
Cancer/Testis Antigens: Expression, Regulation, Tumor Invasion, and Use in Immunotherapy of Cancers.
Esophageal Squamous Cell Carcinoma
CD147 and matrix metalloproteinase-2 protein expression as significant prognostic factors in esophageal squamous cell carcinoma.
Esophageal Squamous Cell Carcinoma
Differential expression of MMP and uPA systems and prognostic relevance of their expression in esophageal squamous cell carcinoma.
Esophageal Squamous Cell Carcinoma
Functional haplotypes in the promoter of matrix metalloproteinase-2 predict risk of the occurrence and metastasis of esophageal cancer.
Esophageal Squamous Cell Carcinoma
Increased expression of MMP-2 and MMP-9 in esophageal squamous cell carcinoma.
Esophageal Squamous Cell Carcinoma
miR-29b inhibits the progression of esophageal squamous cell carcinoma by targeting MMP-2.
Esophageal Squamous Cell Carcinoma
Overexpression of Aurora-A enhances invasion and matrix metalloproteinase-2 expression in esophageal squamous cell carcinoma cells.
Esophageal Squamous Cell Carcinoma
Overexpression of MMP-2 and MMP-9 in esophageal squamous cell carcinoma.
Esophageal Squamous Cell Carcinoma
Phenotypes of human esophageal squamous cell carcinoma based on matrix metalloproteinase production.
Esophageal Squamous Cell Carcinoma
Preliminary evaluation for Bit1 as a potential biomarker for squamous cell carcinoma and adenocarcinoma of esophagus.
Esophageal Squamous Cell Carcinoma
S100A4 mediated cell invasion and metastasis of esophageal squamous cell carcinoma via the regulation of MMP-2 and E-cadherin activity.
Esophageal Squamous Cell Carcinoma
Substance P accelerates the progression of human esophageal squamous cell carcinoma via MMP-2, MMP-9, VEGF-A, and VEGFR1 overexpression.
Esophageal Squamous Cell Carcinoma
The expression and clinical significance of metastasis suppressor gene and matrix metalloproteinase-2 in esophageal squamous cell of carcinoma.
Esophageal Squamous Cell Carcinoma
The influence of matrix metalloproteinase-2, -9, and -12 promoter polymorphisms on Iranian patients with oesophageal squamous cell carcinoma.
Esophageal Squamous Cell Carcinoma
[Clinicopathological significance of expressions of RECK and MMP-2 in esophageal squamous carcinoma]
Esophageal Squamous Cell Carcinoma
[Expression of S100A4 in esophageal squamous cell carcinoma and its relation to tumor invasion and metastasis]
Essential Hypertension
Correlations of MMP-1 and MMP-2 gene polymorphisms with essential hypertension.
Essential Hypertension
Elevated Levels of MMP-9 in Untreated Patients with Stage I Essential Hypertension.
Essential Hypertension
MMP-2 and sTNF-R1 Variability in Patients with Essential Hypertension: 1-Year Follow-Up Study.
Essential Hypertension
Plasma levels of active extracellular matrix metalloproteinases 2 and 9 in patients with essential hypertension before and after antihypertensive treatment.
Essential Hypertension
The effect of Ca2+ channel antagonists on plasma concentrations of matrix metalloproteinase-2 and -9 in essential hypertension.
Exfoliation Syndrome
Matrix metalloproteinase-2, tissue inhibitor of matrix metalloproteinase-2, and transforming growth factor beta 1 in the aqueous humor and serum of patients with pseudoexfoliation syndrome.
Eye Infections
(-)Epigallocatechin-3-gallate inhibits gelatinase activity of some bacterial isolates from ocular infection, and limits their invasion through gelatine.
Factor XIII Deficiency
Association between expression of MMP-2 and MMP-9 genes and pathogenesis of intracranial hemorrhage in severe coagulation factor XIII deficiency.
Factor XIII Deficiency
Expression and CpG island methylation pattern of MMP-2 and MMP-9 genes in patients with congenital factor XIII deficiency and intracranial hemorrhage.
Fanconi Anemia
Cytokines, inducers and inhibitors modulate MMP-2 and MMP?9 secretion by human Fanconi anemia immortalized fibroblasts.
Fanconi Anemia
IL-6, IL-8, MMP-2, MMP-9 are overexpressed in Fanconi anemia cells through a NF-?B/TNF-? dependent mechanism.
Fatty Liver
Deficiency of inducible nitric oxide synthase exacerbates hepatic fibrosis in mice fed high-fat diet.
Fatty Liver
Higher hepatic gene expression and serum levels of matrix metalloproteinase-2 are associated with steatohepatitis in non-alcoholic fatty liver diseases.
Fatty Liver
Sesame oil attenuates nutritional fibrosing steatohepatitis by modulating matrix metalloproteinases-2, 9 and PPAR-?.
Fetal Growth Retardation
Midregional pro-adrenomedullin and matrix metalloproteinase-2 levels in intrauterine growth restriction and small gestational age pregnancies: biochemical diagnostic difference.
Fetal Membranes, Premature Rupture
Expression of a progelatinase activator (MT1-MMP) in human fetal membranes.
Fetal Membranes, Premature Rupture
Programmed cell death (apoptosis) as a possible pathway to metalloproteinase activation and fetal membrane degradation in premature rupture of membranes.
Fibroadenoma
72 KD and 92 KD type IV collagenase, type IV collagen, and laminin mRNAs in breast cancer: a study by in situ hybridization.
Fibroadenoma
Augmented release of matrix metalloproteinase-9 by PKC activation in organotypic cultures of human breast cancer and adjacent normal breast tissue and fibroadenoma.
Fibroadenoma
Expression of gelatinase A and TIMP-2 mRNAs in desmoplastic fibroblasts in both mammary carcinomas and basal cell carcinomas of the skin.
Fibroadenoma
Expression of matrix metalloproteinase 2 and 9 in breast cancer and breast fibroadenoma: a randomized, double-blind study.
Fibroadenoma
Expression of nm23, MMP-2, TIMP-2 in breast neoplasm in Zhengzhou Center Hospital, China.
Fibroadenoma
Immunolocalization of matrix metallo-proteinases and their tissue inhibitor in human mammary pathology.
Fibroadenoma
Increased gelatinase-A and gelatinase-B activities in malignant vs. benign breast tumors.
Fibroadenoma
Plasma levels of matrix metalloproteinases 2 and 9 correlate with histological grade in breast cancer patients.
Fibroadenoma
Production of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human breast carcinomas.
Fibroadenoma
Stromelysin 3 belongs to a subgroup of proteinases expressed in breast carcinoma fibroblastic cells and possibly implicated in tumor progression.
Fibrocystic Breast Disease
Gelatinase A/TIMP-2 imbalance in lymph-node-positive breast carcinomas, as measured by RT-PCR.
Fibroma
Matrix metalloproteinase expression is related to angiogenesis and histologic grade in spindle cell soft tissue neoplasms of the extremities.
Fibroma
Ras levels and metalloproteinase activity in normal versus neoplastic rat mammary tissues.
Fibromatosis, Aggressive
Malignant Fibrous Histiocytoma, Aggressive Fibromatosis and Benign Fibrous Tumors Express mRNA for the Metalloproteinase Inducer EMMPRIN and the Metalloproteinases MMP-2 and MT1-MMP.
Fibromatosis, Gingival
Alteration in expression of MMP-1 and MMP-2 but not TIMP-1 and TIMP-2 in hereditary gingival fibromatosis is mediated by TGF-beta 1 autocrine stimulation.
Fibromatosis, Gingival
Effect of transforming growth factor-beta1, interleukin-6, and interferon-gamma on the expression of type I collagen, heat shock protein 47, matrix metalloproteinase (MMP)-1 and MMP-2 by fibroblasts from normal gingiva and hereditary gingival fibromatosis.
Fibrosarcoma
(-)Epigallocatechin-3-gallate directly inhibits MT1-MMP activity, leading to accumulation of nonactivated MMP-2 at the cell surface.
Fibrosarcoma
3,5-Dicaffeoyl-epi-quinic acid inhibits the PMA-stimulated activation and expression of MMP-9 but not MMP-2 via downregulation of MAPK pathway.
Fibrosarcoma
A small-molecule furin inhibitor inhibits cancer cell motility and invasiveness.
Fibrosarcoma
A specific sequence of the noncollagenous domain of the alpha3(IV) chain of type IV collagen inhibits expression and activation of matrix metalloproteinases by tumor cells.
Fibrosarcoma
Antisense Deoxyoligonucleotides Inhibit Activities of Matrix Metalloproteinase-2 in Human Fibrosarcoma HT1080 Cells.
Fibrosarcoma
Apoptotic efficacy and inhibitory effect of dexamethasone on matrix metalloproteinase.
Fibrosarcoma
Attenuation of melanoma invasion by a secreted variant of activated leukocyte cell adhesion molecule.
Fibrosarcoma
Autocrine induction of tumor protease production and invasion by a metallothionein-regulated TGF-beta 1 (Ser223, 225).
Fibrosarcoma
Biosynthesis and recovery of selenium nanoparticles and the effects on matrix metalloproteinase-2 expression.
Fibrosarcoma
Calcium influx modulates expression of matrix metalloproteinase-2 (72-kDa type IV collagenase, gelatinase A).
Fibrosarcoma
Carbohydrate-mediated regulation of matrix metalloproteinase-2 activation in normal human fibroblasts and fibrosarcoma cells.
Fibrosarcoma
CD97 inhibits cell migration in human fibrosarcoma cells by modulating TIMP-2/MT1- MMP/MMP-2 activity--role of GPS autoproteolysis and functional cooperation between the N- and C-terminal fragments.
Fibrosarcoma
Cellular cholesterol regulates MT1 MMP dependent activation of MMP 2 via MEK-1 in HT1080 fibrosarcoma cells.
Fibrosarcoma
Cellular uptake of proMMP-2:TIMP-2 complexes by the endocytic receptor megalin/LRP-2.
Fibrosarcoma
Characteristics of 92 kDa type IV collagenase/gelatinase produced by granulocytic leukemia cells: structure, expression of cDNA in E. coli and enzymic properties.
Fibrosarcoma
Collagen-binding domains of gelatinase A and thrombospondin-derived peptides impede endocytic clearance of active gelatinase A and promote HT1080 fibrosarcoma cell invasion.
Fibrosarcoma
Comparative effects of EGCG, green tea and a nutrient mixture on the patterns of MMP-2 and MMP-9 expression in cancer cell lines.
Fibrosarcoma
Complete structure of the human gene for 92-kDa type IV collagenase. Divergent regulation of expression for the 92- and 72-kilodalton enzyme genes in HT-1080 cells.
Fibrosarcoma
Constituents of Aquilaria sinensis Leaves Upregulate the Expression of Matrix Metalloproteases 2 and 9.
Fibrosarcoma
Culture of human fibrosarcoma HT-1080 cells in presence of fibronectin activates MMP-2.
Fibrosarcoma
Curcumin, demethoxycurcumin and bisdemethoxycurcumin differentially inhibit cancer cell invasion through the down-regulation of MMPs and uPA.
Fibrosarcoma
Dieckol from Ecklonia cava Regulates Invasion of Human Fibrosarcoma Cells and Modulates MMP-2 and MMP-9 Expression via NF-?B Pathway.
Fibrosarcoma
Differential effects of trichostatin A on gelatinase A expression in 3T3 fibroblasts and HT-1080 fibrosarcoma cells: implications for use of TSA in cancer therapy.
Fibrosarcoma
Dimerization of endogenous MT1-MMP is a regulatory step in the activation of the 72-kDa gelatinase MMP-2 on fibroblasts and fibrosarcoma cells.
Fibrosarcoma
DTD, an anti-inflammatory ditriazine, inhibits angiogenesis in vitro and in vivo.
Fibrosarcoma
Eicosapentaenoic acid reduces the invasive and metastatic activities of malignant tumor cells.
Fibrosarcoma
Epigenetically induced changes in nuclear textural patterns and gelatinase expression in human fibrosarcoma cells.
Fibrosarcoma
Evaluation of matrix metalloproteinases (MMP)-2 and MMP-9 activity in serum and biochemical and hematological parameters in spontaneous canine cutaneous tumors before and after surgical treatment.
Fibrosarcoma
Ginsenoside 20(S)-protopanaxadiol inhibits the proliferation and invasion of human fibrosarcoma HT1080 cells.
Fibrosarcoma
Heat shock suppresses membrane type 1-matrix metalloproteinase production and progelatinase A activation in human fibrosarcoma HT-1080 cells and thereby inhibits cellular invasion.
Fibrosarcoma
Heat shock-mediated transient increase in intracellular 3',5'-cyclic AMP results in tumor specific suppression of membrane type 1-matrix metalloproteinase production and progelatinase A activation.
Fibrosarcoma
Highly activated matrix metalloproteinase-2 secreted from clones of metastatic lung nodules of nude mice injected with human fibrosarcoma HT1080.
Fibrosarcoma
Human fibronectin and MMP-2 collagen binding domains compete for collagen binding sites and modify cellular activation of MMP-2.
Fibrosarcoma
Human protein kinase CK2 phosphorylates matrix metalloproteinase 2 and inhibits its activity.
Fibrosarcoma
Hydrophilic extract from Posidonia oceanica inhibits activity and expression of gelatinases and prevents HT1080 human fibrosarcoma cell line invasion.
Fibrosarcoma
Identification of arachidonic acid pathways required for the invasive and metastatic activity of malignant tumor cells.
Fibrosarcoma
In vitro modulation of MMP-2 and MMP-9 in adult human sarcoma cell lines by cytokines, inducers and inhibitors.
Fibrosarcoma
In vivo and in vitro antitumor effect of ascorbic acid, lysine, proline, arginine, and green tea extract on human fibrosarcoma cells HT-1080.
Fibrosarcoma
Inhibition of human collagenase activity by antisense oligonucleoside methylphosphonates.
Fibrosarcoma
Inhibition of matrix metalloproteinase activity and growth of gastric adenocarcinoma cells by an angiotensin converting enzyme inhibitor in in vitro and murine models.
Fibrosarcoma
Inhibition of the expression on MMP-2, 9 and morphological changes via human fibrosarcoma cell line by 6,6'-bieckol from marine alga Ecklonia cava.
Fibrosarcoma
Inhibitory effect of obovatal on the migration and invasion of HT1080 cells via the inhibition of MMP-2.
Fibrosarcoma
Inhibitory effect of the carnosine-gallic acid synthetic peptide on MMP-2 and MMP-9 in human fibrosarcoma HT1080 cells.
Fibrosarcoma
Inhibitory effects of a benz[f]indole-4,9-dione analog on cancer cell metastasis mediated by the down-regulation of matrix metalloproteinase expression in human HT1080 fibrosarcoma cells.
Fibrosarcoma
Inhibitory effects of caffeic acid phenethyl ester on cancer cell metastasis mediated by the down-regulation of matrix metalloproteinase expression in human HT1080 fibrosarcoma cells.
Fibrosarcoma
Insulin like growth factor-1 selectively regulates the expression of matrix metalloproteinase-2 in malignant H-ras transformed cells.
Fibrosarcoma
Matrix metalloproteinase 2 in tumor cell-induced platelet aggregation: regulation by nitric oxide.
Fibrosarcoma
Matrix metalloproteinase 2 secretion in WEHI 164 fibrosarcoma cells is nitric oxide-related and modified by morphine.
Fibrosarcoma
MicroRNA-29 Family Suppresses the Invasion of HT1080 Human Fibrosarcoma Cells by Regulating Matrix Metalloproteinase 2 Expression.
Fibrosarcoma
Modulation of type IV collagenase and plasminogen activator in a hamster fibrosarcoma by basement membrane components and lung fibroblasts.
Fibrosarcoma
Modulation of u-PA, MMPs and their inhibitors by a novel nutrient mixture in adult human sarcoma cell lines.
Fibrosarcoma
Mosaic structure of the secreted ECM metalloproteases and interaction of the type IV collagenases with inhibitors.
Fibrosarcoma
Near-infrared triple-helical peptide with quenched fluorophores for optical imaging of MMP-2 and MMP-9 proteolytic activity in vivo.
Fibrosarcoma
New N-arylsulfonyl-N-alkoxyaminoacetohydroxamic acids as selective inhibitors of gelatinase A (MMP-2).
Fibrosarcoma
Novel processing of beta-amyloid precursor protein catalyzed by membrane type 1 matrix metalloproteinase releases a fragment lacking the inhibitor domain against gelatinase A.
Fibrosarcoma
Proteolytic processing of membrane-type-1 matrix metalloproteinase is associated with gelatinase A activation at the cell surface.
Fibrosarcoma
Rac1 mediates type I collagen-dependent MMP-2 activation. role in cell invasion across collagen barrier.
Fibrosarcoma
Rapid trafficking of membrane type 1-matrix metalloproteinase to the cell surface regulates progelatinase a activation.
Fibrosarcoma
Regulated Expressions of MMP-2, -9 by Diterpenoids from Euphorbia formosana Hayata.
Fibrosarcoma
Regulation of matrix metalloproteinase-2 (gelatinase A, MMP-2), membrane-type matrix metalloproteinase-1 (MT1-MMP) and tissue inhibitor of metalloproteinases-2 (TIMP-2) expression by elastin-derived peptides in human HT-1080 fibrosarcoma cell line.
Fibrosarcoma
Regulation of membrane-type matrix metalloproteinase-1 expression by growth factors and phorbol 12-myristate 13-acetate.
Fibrosarcoma
Release of gelatinase A (matrix metalloproteinase 2) induced by photolysis of caged phosphatidic acid in HT 1080 metastatic fibrosarcoma cells.
Fibrosarcoma
Repression of stromelysin metalloprotease expression in rat fibrosarcoma cells by dimethylsulfoxide.
Fibrosarcoma
Retinoic acid synergizes with cyclic AMP to enhance MMP-2 basal promoter activity.
Fibrosarcoma
Salinomycin causes migration and invasion of human fibrosarcoma cells by inducing MMP-2 expression via PI3-kinase, ERK-1/2 and p38 kinase pathways.
Fibrosarcoma
Stimulation of the 92-kD type IV collagenase promoter and enzyme expression in human melanoma cells.
Fibrosarcoma
Sulfated glucosamine inhibits MMP-2 and MMP-9 expressions in human fibrosarcoma cells.
Fibrosarcoma
Suppressive effects of electrochemically reduced water on matrix metalloproteinase-2 activities and in vitro invasion of human fibrosarcoma HT1080 cells.
Fibrosarcoma
The activation of ProMMP-2 (gelatinase A) by HT1080 fibrosarcoma cells is promoted by culture on a fibronectin substrate and is concomitant with an increase in processing of MT1-MMP (MMP-14) to a 45 kDa form.
Fibrosarcoma
The C-terminal domain of tissue inhibitor of metalloproteinases-2 is required for cell binding but not for antimetalloproteinase activity.
Fibrosarcoma
The inhibitory mechanism of a novel cationic glucosamine derivative against MMP-2 and MMP-9 expressions.
Fibrosarcoma
Tumor cell invasion through matrigel is regulated by activated matrix metalloproteinase-2.
Fibrosarcoma
Two-dimensional zymography differentiates gelatinase isoforms in stimulated microglial cells and in brain tissues of acute brain injuries.
Fibrosarcoma
Type IV collagen induces matrix metalloproteinase 2 activation in HT1080 fibrosarcoma cells.
Fibrosarcoma
Type IV collagenase activity of a primary HSV-2-induced hamster fibrosarcoma and its in vivo metastases and in vitro clones.
Fluorosis, Dental
[Effect of fluoride on the expression of MMP-20/TIMP-2 in ameloblast of rat incisor and the antagonistic effect of melatonin against fluorosis].
Follicular Cyst
Involvement of Matrix Metalloproteinases and their Inhibitors in Bovine Cystic Ovarian Disease.
Follicular Cyst
Laminin-5 gamma 2 chain is colocalized with gelatinase-A (MMP-2) and collagenase-3 (MMP-13) in odontogenic keratocysts.
Follicular Cyst
Matrix metalloproteinases-2 and -9 activities in bovine follicular fluid of different-sized follicles: relationship to intra-follicular inhibin and steroid concentrations.
Foot Ulcer
Expression of miR-217 and HIF-1?/VEGF pathway in patients with diabetic foot ulcer and its effect on angiogenesis of diabetic foot ulcer rats.
Foot Ulcer
Increased ratio of serum matrix metalloproteinase-9 against TIMP-1 predicts poor wound healing in diabetic foot ulcers.
Frontotemporal Dementia
MMP-9 and MMP-2 Contribute to Neuronal Cell Death in iPSC Models of Frontotemporal Dementia with MAPT Mutations.
Frontotemporal Dementia
Profiles of matrix metalloproteinases and their inhibitors in plasma of patients with dementia.
Gallbladder Neoplasms
Guggulsterone enhances antitumor activity of gemcitabine in gallbladder cancer cells through suppression of NF-?B.
Gastrinoma
[Role of matrix metalloproteinase-2 and components of the extracellular matrix--collagen type IV and laminin expression in detection of the invasive potential of pancreatic tumors]
Gastritis
Enhanced systemic matrix metalloproteinase response in Helicobacter pylori gastritis.
Gastritis
Gastric gelatinase B/matrix metalloproteinase-9 is rapidly increased in Helicobacter felis-induced gastritis.
Gastrointestinal Neoplasms
Serum levels of matrix metalloproteinase-2 and -9 and conventional tumor markers (CEA and CA 19-9) in patients with colorectal and gastric cancers.
Gastrointestinal Stromal Tumors
[Correlation between expressions of matrix metalloproteinase-2 & 9 and vasculogenic mimicry in gastrointestinal stromal tumors]
gelatinase a deficiency
Angiotensin Type 1 Receptor Blocker Reduces Intimal Neovascularization and Plaque Growth in Apolipoprotein E-Deficient Mice.
gelatinase a deficiency
Clinical and radiographic findings in two brothers affected with a novel mutation in matrix metalloproteinase 2 gene.
gelatinase a deficiency
Comparative Serum Analyses Identify Cytokines and Hormones Commonly Dysregulated as Well as Implicated in Promoting Osteolysis in MMP-2-Deficient Mice and Children.
gelatinase a deficiency
Deficiency in matrix metalloproteinase-2 results in long-term vascular instability and regression in the injured mouse spinal cord.
gelatinase a deficiency
Differential Actions of the Endocytic Collagen Receptor uPARAP/Endo180 and the Collagenase MMP-2 in Bone Homeostasis.
gelatinase a deficiency
Effect of MMP-2 deficiency on atherosclerotic lesion formation in apoE-deficient mice.
gelatinase a deficiency
Emergence of a metalloproteinase / phospholipase A2 axis of systemic inflammation.
gelatinase a deficiency
Interleukin (IL)-23 mediates Toxoplasma gondii-induced immunopathology in the gut via matrixmetalloproteinase-2 and IL-22 but independent of IL-17.
gelatinase a deficiency
Loss of Matrix Metalloproteinase-2 Amplifies Murine Toxin-Induced Liver Fibrosis by Upregulating Collagen I Expression.
gelatinase a deficiency
Matrix Metalloproteinase-2 (MMP-2) Gene Deletion Enhances MMP-9 Activity, Impairs PARP-1 Degradation, and Exacerbates Hepatic Ischemia and Reperfusion Injury in Mice.
gelatinase a deficiency
Matrix metalloproteinase-2 deficiency impairs aortic atherosclerotic calcification in ApoE-deficient mice.
gelatinase a deficiency
Matrix metalloproteinase-2 deletions protect against hemorrhagic transformation after 1h of cerebral ischemia and 23h of reperfusion.
gelatinase a deficiency
Matrix metalloproteinase-2 facilitates wound healing events that promote functional recovery after spinal cord injury.
gelatinase a deficiency
Matrix Metalloproteinase-2 Mediates a Mechanism of Metabolic Cardioprotection Consisting of Negative Regulation of the Sterol Regulatory Element-Binding Protein-2/3-Hydroxy-3-Methylglutaryl-CoA Reductase Pathway in the Heart.
gelatinase a deficiency
Matrix metalloproteinase-2 or -9 deletions protect against hemorrhagic transformation during early stage of cerebral ischemia and reperfusion.
gelatinase a deficiency
Matrix metalloproteinase-2 regulates the expression of tissue inhibitor of matrix metalloproteinase-2.
gelatinase a deficiency
Mechanisms underlying the impairment of ischemia-induced neovascularization in matrix metalloproteinase 2-deficient mice.
gelatinase a deficiency
Modulation of Systemic Metabolism by MMP-2: From MMP-2 Deficiency in Mice to MMP-2 Deficiency in Patients.
gelatinase a deficiency
Pathologies of matrix metalloproteinase-2 underactivity: a perspective on a neglected condition 1.
gelatinase b deficiency
In vivo activation of gelatinase B/MMP-9 by trypsin in acute pancreatitis is a permissive factor in streptozotocin-induced diabetes.
gelatinase b deficiency
Matrix metalloproteinase-2 or -9 deletions protect against hemorrhagic transformation during early stage of cerebral ischemia and reperfusion.
gelatinase b deficiency
Mmp-9 deficiency enhances collagenase-induced intracerebral hemorrhage and brain injury in mutant mice.
Genetic Diseases, Inborn
A crucial role for matrix metalloproteinase 2 in osteocytic canalicular formation and bone metabolism.
Genetic Diseases, Inborn
Dermal fibroblasts from pseudoxanthoma elasticum patients have raised MMP-2 degradative potential.
Geographic Atrophy
MMP-2 Rs24386 (C-->T) gene polymorphism and the phenotype of age-related macular degeneration.
Gestational Trophoblastic Disease
[MMP-2/TIMP-2 expression in the trophoblasts of patients with gestational trophoblastic disease]
Giant Cell Arteritis
Elevated levels of 92-kd type IV collagenase (matrix metalloproteinase 9) in giant cell arteritis.
Giant Cell Arteritis
Macrophages contain 92-kd gelatinase (MMP-9) at the site of degenerated internal elastic lamina in temporal arteritis.
Giant Cell Arteritis
Metalloproteinase-2 and -9 in giant cell arteritis: involvement in vascular remodeling.
Giant Cell Arteritis
Serum MMP-2 and MMP-9 in patients with Behçet's disease: Do their higher levels correlate to vasculo-Behçet's disease associated with aneurysm formation?
Giant Cell Tumor of Bone
Regulation of MMP-9 (92 kDa type IV collagenase/gelatinase B) expression in stromal cells of human giant cell tumor of bone.
Giant Cell Tumors
Activation of MMP-2 by human GCT23 giant cell tumour cells induced by osteopontin, bone sialoprotein and GRGDSP peptides is RGD and cell shape change dependent.
Giant Cell Tumors
Regulation of MMP-9 (92 kDa type IV collagenase/gelatinase B) expression in stromal cells of human giant cell tumor of bone.
Gingival Diseases
Activity of matrix metalloproteinase-2 (MMP-2) in canine oronasal tumors.
Gingival Overgrowth
Cyclosporin A inhibits production and activity of matrix metalloproteinases by gingival fibroblasts.
Gingival Overgrowth
Evaluation of inductive effects of different concentrations of cyclosporine A on MMP-1, MMP-2, MMP-3, TIMP-1, and TIMP-2 in fetal and adult human gingival fibroblasts.
Gingival Overgrowth
Local Inflammation Alters MMP-2 and MMP-9 Gelatinase Expression Associated with the Severity of Nifedipine-Induced Gingival Overgrowth: a Rat Model Study.
Gingival Overgrowth
Molecular events associated with ciclosporin?A-induced gingival overgrowth are attenuated by Smad7 overexpression in fibroblasts.
Gingivitis
Levels of metalloproteinase-2 and -9 and tissue inhibitor of matrix metalloproteinase-1 in gingival crevicular fluid of patients with periodontitis, gingivitis, and healthy gingiva.
Gingivitis
[Expression of MMP-2 and MMP-3 in periodontal tissues of rat periodontitis model]
Glaucoma
A feasible tool to detect mRNA expression of matrix metalloproteinases and their tissue inhibitors in human Tenon's capsule.
Glaucoma
Alteration of MCP-1 and MMP-9 in aqueous humor is associated with secondary glaucoma in Fuchs uveitis syndrome.
Glaucoma
Altered transcripts expression of matrix metalloproteinases and their tissue inhibitors in tenon capsule of patients with glaucoma.
Glaucoma
Connective tissue growth factor and tissue inhibitor of matrix metalloproteinase-2 in patients with exfoliative glaucoma.
Glaucoma
Decreased TNF Levels and Improved Retinal Ganglion Cell Survival in MMP-2 Null Mice Suggest a Role for MMP-2 as TNF Sheddase.
Glaucoma
Effect of cyclical mechanical stretch and exogenous transforming growth factor-beta1 on matrix metalloproteinase-2 activity in lamina cribrosa cells from the human optic nerve head.
Glaucoma
Identification of ocular matrix metalloproteinases present within the aqueous humor and iridocorneal drainage angle tissue of normal and glaucomatous canine eyes.
Glaucoma
Increased expression of matrix metalloproteinases in mononuclear blood cells of normal-tension glaucoma patients.
Glaucoma
Latanoprost therapy reduces the levels of TGF beta 1 and gelatinases in the aqueous humour of patients with exfoliative glaucoma.
Glaucoma
Levels and activation of matrix metalloproteinases in aqueous humor are elevated in uveitis-related secondary glaucoma.
Glaucoma
Matrix metalloproteinases and their inhibitors in aqueous humor of patients with pseudoexfoliation syndrome/glaucoma and primary open-angle glaucoma.
Glaucoma
Trabodenoson on trabecular meshwork rejuvenation: a comprehensive review of clinical data.
Glaucoma
[Expression of matrix metalloproteinases and inhibitors on the scleral tissue of lamina cribrosa in rat with experimental chronic ocular hypertension]
Glaucoma, Angle-Closure
Altered transcripts expression of matrix metalloproteinases and their tissue inhibitors in tenon capsule of patients with glaucoma.
Glaucoma, Open-Angle
Altered transcripts expression of matrix metalloproteinases and their tissue inhibitors in tenon capsule of patients with glaucoma.
Glaucoma, Open-Angle
Correlations of TIMP2 and TIMP3 gene polymorphisms with primary open-angle glaucoma.
Glaucoma, Open-Angle
Effect of cyclical mechanical stretch and exogenous transforming growth factor-beta1 on matrix metalloproteinase-2 activity in lamina cribrosa cells from the human optic nerve head.
Glaucoma, Open-Angle
Hyaluronic acid increases MMP-2 and MMP-9 expressions in cultured trabecular meshwork cells from patients with primary open-angle glaucoma.
Glaucoma, Open-Angle
Involvement of inflammation, degradation, and apoptosis in a mouse model of glaucoma.
Glaucoma, Open-Angle
Levels and activation of matrix metalloproteinases in aqueous humor are elevated in uveitis-related secondary glaucoma.
Glaucoma, Open-Angle
The Protective Role of the -735C/T and the -1306C/T Polymorphisms of the MMP-2 Gene in the Development of Primary Open-angle Glaucoma.
Glioblastoma
Activated isoforms of MMP-2 are induced in U87 human glioma cells in response to beta-amyloid peptide.
Glioblastoma
Activation of sonic hedgehog signaling enhances cell migration and invasion by induction of matrix metalloproteinase-2 and -9 via the phosphoinositide-3 kinase/AKT signaling pathway in glioblastoma.
Glioblastoma
Adenovirus-mediated transfer of siRNA against MMP-2 mRNA results in impaired invasion and tumor-induced angiogenesis, induces apoptosis in vitro and inhibits tumor growth in vivo in glioblastoma.
Glioblastoma
Aldehyde dehydrogenase 1A1 circumscribes high invasive glioma cells and predicts poor prognosis.
Glioblastoma
Andrographolide suppresses the migratory ability of human glioblastoma multiforme cells by targeting ERK1/2-mediated matrix metalloproteinase-2 expression.
Glioblastoma
Arsenic Trioxide Induces Apoptosis and Incapacitates Proliferation and Invasive Properties of U87MG Glioblastoma Cells through a Possible NF-?B-Mediated Mechanism.
Glioblastoma
Autocrine Production of PDGF Stimulated by the Tenascin-C-Derived Peptide TNIIIA2 Induces Hyper-Proliferation in Glioblastoma Cells.
Glioblastoma
Bacitracin Inhibits the Migration of U87-MG Glioma Cells via Interferences of the Integrin Outside-in Signaling Pathway.
Glioblastoma
Calpain 2 is required for glioblastoma cell invasion: regulation of matrix metalloproteinase 2.
Glioblastoma
Cannabinoids inhibit glioma cell invasion by down-regulating matrix metalloproteinase-2 expression.
Glioblastoma
Characterization of matrix metalloproteinase-2 and -9, ADAM-10 and N-cadherin expression in human glioblastoma multiforme.
Glioblastoma
Chitosan-Doxycycline hydrogel: an MMP inhibitor/sclerosing embolizing agent as a new approach to endoleak prevention and treatment after endovascular aneurysm repair.
Glioblastoma
Comparative effects of EGCG, green tea and a nutrient mixture on the patterns of MMP-2 and MMP-9 expression in cancer cell lines.
Glioblastoma
CRM197 in Combination With shRNA Interference of VCAM-1 Displays Enhanced Inhibitory Effects on Human Glioblastoma Cells.
Glioblastoma
Cysteinyl Leukotriene Receptor Antagonists Inhibit Migration, Invasion, and Expression of MMP-2/9 in Human Glioblastoma.
Glioblastoma
Differential expression of membrane-type matrix metalloproteinase and its correlation with gelatinase A activation in human malignant brain tumors in vivo and in vitro.
Glioblastoma
Downregulation of Akt and FAK phosphorylation reduces invasion of glioblastoma cells by impairment of MT1-MMP shuttling to lamellipodia and downregulates MMPs expression.
Glioblastoma
Effect of cisplatin and BCNU on MMP-2 levels in human glioblastoma cell lines in vitro.
Glioblastoma
Effect of resveratrol on matrix metalloproteinase-2 (MMP-2) and Secreted Protein Acidic and Rich in Cysteine (SPARC) on human cultured glioblastoma cells.
Glioblastoma
Effect of Ukrain on matrix metalloproteinase-2 and Secreted Protein Acidic and Rich in Cysteine (SPARC) expression in human glioblastoma cells.
Glioblastoma
Epigenetic Control of the Invasion-promoting MT1-MMP/MMP-2/TIMP-2 Axis in Cancer Cells.
Glioblastoma
Expression and localization of 72 kDa type IV collagenase (MMP-2) in human malignant gliomas in vivo.
Glioblastoma
Expression and prognostic impact of matrix metalloproteinase-2 (MMP-2) in astrocytomas.
Glioblastoma
Expression and tissue localization of membrane-type 1, 2, and 3 matrix metalloproteinases in human astrocytic tumors.
Glioblastoma
Expression of adhesion factors and degrading proteins in primary and secondary glioblastomas and their precursor tumors.
Glioblastoma
Expression of hepatocyte growth factor and matrix metalloproteinase-2 in human glioma.
Glioblastoma
Expression of matrix metalloproteinases and their tissue inhibitors in human brain tumors.
Glioblastoma
Expression of matrix metalloproteinases, their inhibitors, and urokinase plasminogen activator in human meningiomas.
Glioblastoma
Expression of MMP-2, MMP-7, MMP-9, MMP-10 and MMP-11 in human astrocytic and oligodendroglial gliomas.
Glioblastoma
Gabexate mesilate inhibits colon cancer growth, invasion, and metastasis by reducing matrix metalloproteinases and angiogenesis.
Glioblastoma
Glioblastoma inhibition by cell surface immunoglobulin protein EWI-2, in vitro and in vivo.
Glioblastoma
Green tea polyphenol (-)-epigallocatechin 3-gallate inhibits MMP-2 secretion and MT1-MMP-driven migration in glioblastoma cells.
Glioblastoma
Human chorionic gonadotropin ? induces cell motility via ERK1/2 and MMP-2 activation in human glioblastoma U87MG cells.
Glioblastoma
IL-6 augments the invasiveness of U87MG human glioblastoma multiforme cells via up-regulation of MMP-2 and fascin-1.
Glioblastoma
In Silico prediction of the molecular basis of ClTx and AaCTx interaction with matrix metalloproteinase-2 (MMP-2) to inhibit glioma cell invasion.
Glioblastoma
Increased expression of gelatinase-a and timp-2 in primary human glioblastomas.
Glioblastoma
Inhibition of Necl-5 (CD155/PVR) reduces glioblastoma dispersal and decreases MMP-2 expression and activity.
Glioblastoma
Localization of gelatinase activities in glioma tissues by film in situ zymography.
Glioblastoma
Low-density lipoprotein receptor-related protein 1 promotes cancer cell migration and invasion by inducing the expression of matrix metalloproteinases 2 and 9.
Glioblastoma
Low-dose chemotherapy combined with an antiangiogenic drug reduces human glioma growth in vivo.
Glioblastoma
Matrix metalloproteinase 2 (MMP-2) immunoreactive protein is associated with poor grade and survival in brain neoplasms.
Glioblastoma
Matrix metalloproteinase-2 and -9 in glioblastoma: a trio of old drugs-captopril, disulfiram and nelfinavir-are inhibitors with potential as adjunctive treatments in glioblastoma.
Glioblastoma
Matrix metalloproteinase-2 gene polymorphism is not associated with increased glioblastoma multiforme susceptibility: an Indian institutional experience.
Glioblastoma
Matrix metalloproteinases in human gliomas: activation of matrix metalloproteinase-2 (MMP-2) may be correlated with membrane-type-1 matrix metalloproteinase (MT1-MMP) expression.
Glioblastoma
Melatonin antagonizes hypoxia-mediated glioblastoma cell migration and invasion via inhibition of HIF-1?.
Glioblastoma
Modulation of MMP-2 and MMP-9 secretion by cytokines, inducers and inhibitors in human glioblastoma T-98G cells.
Glioblastoma
Moesin Up-regulation Is Associated with Enhanced Tumor Progression Imaged Non-invasively in an Orthotopic Mouse Model of Human Glioblastoma.
Glioblastoma
Naringin inhibits the invasion and migration of human glioblastoma cell via downregulation of MMP-2 and MMP-9 expression and inactivation of p38 signaling pathway.
Glioblastoma
PAX6 suppresses the invasiveness of glioblastoma cells and the expression of the matrix metalloproteinase-2 gene.
Glioblastoma
PEG-co-PCL nanoparticles modified with MMP-2/9 activatable low molecular weight protamine for enhanced targeted glioblastoma therapy.
Glioblastoma
PEITC inhibits human brain glioblastoma GBM 8401 cell migration and invasion through the inhibition of uPA, Rho A, and Ras with inhibition of MMP-2, -7 and -9 gene expression.
Glioblastoma
Protein kinase C activation by phorbol ester increases in vitro invasion through regulation of matrix metalloproteinases/tissue inhibitors of metalloproteinases system in D54 human glioblastoma cells.
Glioblastoma
Regulation of matrix metalloproteinase-2 (MMP-2) by hepatocyte growth factor/scatter factor (HGF/SF) in human glioma cells: HGF/SF enhances MMP-2 expression and activation accompanying up-regulation of membrane type-1 MMP.
Glioblastoma
Signaling pathways mediating manganese-induced toxicity in human glioblastoma cells (u87).
Glioblastoma
Silencing microRNA-221/222 cluster suppresses glioblastoma angiogenesis by suppressor of cytokine signaling-3-dependent JAK/STAT pathway.
Glioblastoma
Specificity Protein 1 Expression Contributes to Bcl-w-Induced Aggressiveness in Glioblastoma Multiforme.
Glioblastoma
Sublethal dose of irradiation enhances invasion of malignant glioma cells through p53-MMP 2 pathway in U87MG mouse brain tumor model.
Glioblastoma
Sulindac and its metabolites inhibit invasion of glioblastoma cells via down-regulation of Akt/PKB and MMP-2.
Glioblastoma
Targeting NFE2L2, a transcription factor upstream of MMP-2: A potential therapeutic strategy for temozolomide resistant glioblastoma.
Glioblastoma
Targeting the MMP-14/MMP-2/integrin ?v?3 axis with multispecific N-TIMP2-based antagonists for cancer therapy.
Glioblastoma
Thymoquinone reduces migration and invasion of human glioblastoma cells associated with FAK, MMP-2 and MMP-9 down-regulation.
Glioblastoma
TRAIL inhibits angiogenesis stimulated by VEGF expression in human glioblastoma cells.
Glioblastoma
Tricetin suppresses the migration/invasion of human glioblastoma multiforme cells by inhibiting matrix metalloproteinase-2 through modulation of the expression and transcriptional activity of specificity protein 1.
Glioblastoma
Upregulation of tissue inhibitor of metalloproteinases (TIMP)-2 promotes matrix metalloproteinase (MMP)-2 activation and cell invasion in a human glioblastoma cell line.
Glioblastoma
Vascular cell adhesion molecule-1-mediated matrix metalloproteinase-2 induction in peripheral blood T cells is up-regulated in patients with HTLV-I-associated myelopathy.
Glioblastoma
Vascular endothelial growth factor expression correlates with matrix metalloproteinases MT1-MMP, MMP-2 and MMP-9 in human glioblastomas.
Glioblastoma
Verbascoside Inhibits Glioblastoma Cell Proliferation, Migration and Invasion While Promoting Apoptosis Through Upregulation of Protein Tyrosine Phosphatase SHP-1 and Inhibition of STAT3 Phosphorylation.
Glioblastoma
[Corrigendum] Activation of sonic hedgehog signaling enhances cell migration and invasion by induction of matrix metalloproteinase-2 and -9 via the phosphoinositide-3 kinase/AKT signaling pathway in glioblastoma.
Glioblastoma
[Increased expression of gelatinases A and B, matrilysin and TIMP-1 genes in human malignant gliomas ]
Glioma
A model of BmK CT in inhibiting glioma cell migration via matrix metalloproteinase-2 from experimental and molecular dynamics simulation study
Glioma
A model of BmK CT in inhibiting glioma cell migration via matrix metalloproteinase-2 from experimental and molecular dynamics simulation study.
Glioma
A potential strategy for high-grade gliomas: combination treatment with lithium chloride and BmK CT.
Glioma
Aberrant FoxM1B expression increases matrix metalloproteinase-2 transcription and enhances the invasion of glioma cells.
Glioma
Activated isoforms of MMP-2 are induced in U87 human glioma cells in response to beta-amyloid peptide.
Glioma
Activated leukocyte cell adhesion molecule is expressed in neuroepithelial neoplasms and decreases with tumor malignancy, matrix metalloproteinase 2 expression, and absence of IDH1R132H mutation.
Glioma
Activating transcription factor 3 is overexpressed in human glioma and its knockdown in glioblastoma cells causes growth inhibition both in vitro and in vivo.
Glioma
Activation of matrix metalloproteinase-2 (MMP-2) by membrane type 1 matrix metalloproteinase through an artificial receptor for proMMP-2 generates active MMP-2.
Glioma
Activation of NMDA receptor of glutamate influences MMP-2 activity and proliferation of glioma cells.
Glioma
Adenoviral vectors expressing fusogenic membrane glycoproteins activated via matrix metalloproteinase cleavable linkers have significant antitumor potential in the gene therapy of gliomas.
Glioma
Adenovirus-mediated expression of BmK CT suppresses growth and invasion of rat C6 glioma cells
Glioma
Adenovirus-mediated expression of BmK CT suppresses growth and invasion of rat C6 glioma cells.
Glioma
Adenovirus-mediated transfer of siRNA against MMP-2 mRNA results in impaired invasion and tumor-induced angiogenesis, induces apoptosis in vitro and inhibits tumor growth in vivo in glioblastoma.
Glioma
All-trans retinoic acid inhibits migration, invasion and proliferation, and promotes apoptosis in glioma cells in vitro.
Glioma
Angiopoietin 2 induces glioma cell invasion by stimulating matrix metalloprotease 2 expression through the alphavbeta1 integrin and focal adhesion kinase signaling pathway.
Glioma
Angiopoietin-2 induces human glioma invasion through the activation of matrix metalloprotease-2.
Glioma
Anti-inflammatory effects of serum isolated from animals on intermittent feeding in C6 glioma cell line.
Glioma
Anti-vascular endothelial growth factor therapy-induced glioma invasion is associated with accumulation of Tie2-expressing monocytes.
Glioma
Antitumor progression potential of caffeic acid phenethyl ester involving p75(NTR) in C6 glioma cells.
Glioma
Association of increased phosphatidylinositol 3-kinase signaling with increased invasiveness and gelatinase activity in malignant gliomas.
Glioma
Association of matrix metalloproteinase 2 plasma level with response and survival in patients treated with bevacizumab for recurrent high-grade glioma.
Glioma
Baicalein reduces the invasion of glioma cells via reducing the activity of p38 signaling pathway.
Glioma
BmK CT and 125I-BmK CT suppress the invasion of glioma cells in vitro via matrix metalloproteinase-2.
Glioma
BRG1 expression is increased in human glioma and controls glioma cell proliferation, migration and invasion in vitro.
Glioma
BRMS1 suppresses glioma progression by regulating invasion, migration and adhesion of glioma cells.
Glioma
Cannabinoids inhibit glioma cell invasion by down-regulating matrix metalloproteinase-2 expression.
Glioma
Captopril inhibits Matrix Metalloproteinase-2 and extends survival as a temozolomide adjuvant in an intracranial gliosarcoma model.
Glioma
CCL5 of glioma-associated microglia/macrophages regulates glioma migration and invasion via calcium-dependent matrix metalloproteinase 2.
Glioma
CCR7 Mediates TGF-?1-Induced Human Malignant Glioma Invasion, Migration, and Epithelial-Mesenchymal Transition by Activating MMP2/9 Through the Nuclear Factor KappaB Signaling Pathway.
Glioma
CD44 expression and MMP-2 secretion by mouse glioma cells: effect of interferon and anti-CD44 antibody.
Glioma
Cerebrospinal fluid matrix metalloproteinase-9 increases during treatment of recurrent malignant gliomas.
Glioma
CHI3L1 (YKL-40) is expressed in human gliomas and regulates the invasion, growth and survival of glioma cells.
Glioma
Chlorotoxin Fused to IgG-Fc Inhibits Glioblastoma Cell Motility via Receptor-Mediated Endocytosis.
Glioma
Chronic Intermittent Ethanol Exposure Induces Upregulation of Matrix Metalloproteinase-9 in the Rat Medial Prefrontal Cortex and Hippocampus.
Glioma
Combination of lithium chloride and pEGFP-N1-BmK CT effectively decreases proliferation and migration of C6 glioma cells.
Glioma
Construction and Evaluation of the Tumor-Targeting, Cell-Penetrating Multifunctional Molecular Probe iCREKA.
Glioma
Coronarin D suppresses proliferation, invasion and migration of glioma cells via activating JNK signaling pathway.
Glioma
CTHRC1 mediates multiple pathways regulating cell invasion, migration and adhesion in glioma.
Glioma
Current Biochemical Applications and Future Prospects of Chlorotoxin in Cancer Diagnostics and Therapeutics.
Glioma
Cysteinyl Leukotriene Receptor Antagonists Inhibit Migration, Invasion, and Expression of MMP-2/9 in Human Glioblastoma.
Glioma
Decrease of endogenous vascular endothelial growth factor may not affect glioma cell proliferation and invasion.
Glioma
Destruction of vasculogenic mimicry channels by targeting epirubicin plus celecoxib liposomes in treatment of brain glioma.
Glioma
Dexamethasone reduced invasiveness of human malignant glioblastoma cells through a MAPK phosphatase-1 (MKP-1) dependent mechanism.
Glioma
Differential expression of laminin and fibronectin and of their related metalloproteinases in human glioma cell lines: relation to invasion.
Glioma
Differential expression of membrane-type matrix metalloproteinase and its correlation with gelatinase A activation in human malignant brain tumors in vivo and in vitro.
Glioma
Discoidin domain receptor-1a (DDR1a) promotes glioma cell invasion and adhesion in association with matrix metalloproteinase-2.
Glioma
Dlxin-1, a member of MAGE family, inhibits cell proliferation, invasion and tumorigenicity of glioma stem cells.
Glioma
Downregulation of astrocyte elevated gene-1 expression inhibits the development of vasculogenic mimicry in gliomas.
Glioma
EFEMP2 is upregulated in gliomas and promotes glioma cell proliferation and invasion.
Glioma
Effect of cisplatin and BCNU on MMP-2 levels in human glioblastoma cell lines in vitro.
Glioma
Effect of photodynamic therapy combined with torasemide on the expression of matrix metalloproteinase 2 and sodium-potassium-chloride cotransporter 1 in rat peritumoral edema and glioma.
Glioma
Enhancement of invadopodia activity in glioma cells by sublethal doses of irradiation and temozolomide.
Glioma
Exosomes from glioma cells induce a tumor-like phenotype in mesenchymal stem cells by activating glycolysis.
Glioma
Exploitation of astrocytes by glioma cells to facilitate invasiveness: a mechanism involving matrix metalloproteinase-2 and the urokinase-type plasminogen activator-plasmin cascade.
Glioma
Expression and function of chondroitin 4-sulfate and chondroitin 6-sulfate in human glioma.
Glioma
Expression and localization of 72 kDa type IV collagenase (MMP-2) in human malignant gliomas in vivo.
Glioma
Expression and localization of 92 kDa type IV collagenase/gelatinase B (MMP-9) in human gliomas.
Glioma
Expression and quantitative analysis of matrix metalloproteinase-2 and -9 in human gliomas.
Glioma
Expression of 72 kDa type IV collagenase and invasion activity of human glioma cells.
Glioma
Expression of hepatocyte growth factor and matrix metalloproteinase-2 in human glioma.
Glioma
Expression of MMP-2, MMP-7, MMP-9, MMP-10 and MMP-11 in human astrocytic and oligodendroglial gliomas.
Glioma
Expression pattern of osteopontin splice variants and its functions on cell apoptosis and invasion in glioma cells.
Glioma
FRK controls migration and invasion of human glioma cells by regulating JNK/c-Jun signaling.
Glioma
Functional cooperativity by direct interaction between PAK4 and MMP-2 in the regulation of anoikis resistance, migration and invasion in glioma.
Glioma
Gelatinolytic activity of matrix metalloproteinase-2 and matrix metalloproteinase-9 in rat brain after implantation of 9L rat glioma cells.
Glioma
Genistein Suppression of Matrix Metalloproteinase 2 (MMP-2) and Vascular Endothelial Growth Factor (VEGF) Expression in Mesenchymal Stem Cell Like Cells Isolated from High and Low Grade Gliomas
Glioma
Girdin, an actin-binding protein, is critical for migration, adhesion, and invasion of human glioblastoma cells.
Glioma
Glioblastoma inhibition by cell surface immunoglobulin protein EWI-2, in vitro and in vivo.
Glioma
Glioma cell extracellular matrix metalloproteinase inducer (EMMPRIN) (CD147) stimulates production of membrane-type matrix metalloproteinases and activated gelatinase A in co-cultures with brain-derived fibroblasts.
Glioma
Glioma invasion in vitro: regulation by matrix metalloprotease-2 and protein kinase C.
Glioma
In Silico prediction of the molecular basis of ClTx and AaCTx interaction with matrix metalloproteinase-2 (MMP-2) to inhibit glioma cell invasion.
Glioma
In vitro expression of MMP-2 and MMP-9 in glioma cells following exposure to inflammatory mediators.
Glioma
In vivo glioma growth requires host-derived matrix metalloproteinase 2 for maintenance of angioarchitecture.
Glioma
Increased expression of MMP-2 and MMP-9 indicates poor prognosis in glioma recurrence.
Glioma
Induction of membrane-type-1 matrix metalloproteinase by epidermal growth factor-mediated signaling in gliomas.
Glioma
Inflammatory cytokine modulation of matrix metalloproteinase expression and invasiveness of glioma cells in a 3-dimensional collagen matrix.
Glioma
Inhibition of glioblastoma growth and invasion by (125)I brachytherapy in rat glioma model.
Glioma
Inhibition of matrix degrading enzymes and invasion in human glioblastoma (U87MG) cells by isoflavones.
Glioma
Inhibition of metalloproteinases derived from tumours: new insights in the treatment of human glioblastoma.
Glioma
Inhibition of Necl-5 (CD155/PVR) reduces glioblastoma dispersal and decreases MMP-2 expression and activity.
Glioma
Inhibitory effect of penta-acetyl geniposide on C6 glioma cells metastasis by inhibiting matrix metalloproteinase-2 expression involved in both the PI3K and ERK signaling pathways.
Glioma
Insulin-like growth factor binding protein 2 enhances glioblastoma invasion by activating invasion-enhancing genes.
Glioma
Invasion of brain tissue by primary glioma: evidence for the involvement of urokinase-type plasminogen activator as an activator of type IV collagenase.
Glioma
Ionizing Radiation Enhances Matrix Metalloproteinase-2 Secretion and Invasion of Glioma Cells through Src/Epidermal Growth Factor Receptor-Mediated p38/Akt and Phosphatidylinositol 3-Kinase/Akt Signaling Pathways.
Glioma
Ionizing radiation-inducible miR-494 promotes glioma cell invasion through EGFR stabilization by targeting p190B RhoGAP.
Glioma
Irradiation differentially affects substratum-dependent survival, adhesion, and invasion of glioblastoma cell lines.
Glioma
Lactate promotes glioma migration by TGF-beta2 dependent regulation of matrix metalloproteinase-2.
Glioma
Layilin enhances the invasive ability of malignant glioma cells via SNAI1 signaling.
Glioma
Local intracerebral delivery of endogenous inhibitors by osmotic minipumps effectively suppresses glioma growth in vivo.
Glioma
Long Non-coding RNA LINC00339 Stimulates Glioma Vasculogenic Mimicry Formation by Regulating the miR-539-5p/TWIST1/MMPs Axis.
Glioma
Low-density lipoprotein receptor-related protein contributes to the antiangiogenic activity of thrombospondin-2 in a murine glioma model.
Glioma
Matrix metalloproteinase triggered size-shrinkable gelatin-gold fabricated nanoparticles for tumor microenvironment sensitive penetration and diagnosis of glioma.
Glioma
Matrix metalloproteinase-2 gene polymorphism is not associated with increased glioblastoma multiforme susceptibility: an Indian institutional experience.
Glioma
Matrix metalloproteinase-2 regulates vascular patterning and growth affecting tumor cell survival and invasion in GBM.
Glioma
Matrix metalloproteinases and tissue inhibitors of metalloproteinases in human gliomas.
Glioma
Matrix metalloproteinases in human gliomas: activation of matrix metalloproteinase-2 (MMP-2) may be correlated with membrane-type-1 matrix metalloproteinase (MT1-MMP) expression.
Glioma
Melatonin suppresses migration and invasion via inhibition of oxidative stress pathway in glioma cells.
Glioma
MicroRNA-140-5p inhibits cell proliferation and invasion by regulating VEGFA/MMP2 signaling in glioma.
Glioma
Migfilin promotes migration and invasion in glioma by driving EGFR and MMP-2 signalings: A positive feedback loop regulation.
Glioma
miR-150-5p and miR-133a suppress glioma cell proliferation and migration through targeting membrane-type-1 matrix metalloproteinase.
Glioma
MMP-2 downregulation mediates differential regulation of cell death via ErbB-2 in glioma xenografts.
Glioma
Modulation of phorbol ester-induced regulation of matrix metalloproteinases and tissue inhibitors of metalloproteinases by SB203580, a specific inhibitor of p38 mitogen-activated protein kinase.
Glioma
Mutations in isocitrate dehydrogenase 2 accelerate glioma cell migration via matrix metalloproteinase-2 and 9
Glioma
Mutations in isocitrate dehydrogenase 2 accelerate glioma cell migration via matrix metalloproteinase-2 and 9.
Glioma
N-(2-18F-fluoropropionyl)-l-glutamate as a potential oncology tracer for PET imaging of glioma.
Glioma
Neurokinin-1 receptor directly mediates glioma cell migration by up-regulation of matrix metalloproteinase-2 (MMP-2) and membrane type 1-matrix metalloproteinase (MT1-MMP).
Glioma
Non-apoptotic Fas signaling regulates invasiveness of glioma cells and modulates MMP-2 activity via NFkappaB-TIMP-2 pathway.
Glioma
Noninvasive evaluation of radiation-enhanced glioma cells invasiveness by ultra-high-field (1)H-MRS in vitro.
Glioma
Novel anti IGFBP2 single chain variable fragment inhibits glioma cell migration and invasion.
Glioma
Overexpression of phospholipase D enhances matrix metalloproteinase-2 expression and glioma cell invasion via protein kinase C and protein kinase A/NF-kappaB/Sp1-mediated signaling pathways.
Glioma
Overexpression of riboflavin transporter 2 contributes toward progression and invasion of glioma.
Glioma
Phosphoglycerate dehydrogenase induces glioma cells proliferation and invasion by stabilizing forkhead box M1.
Glioma
Protein kinase C-mediated in vitro invasion of human glioma cells through extracellular-signal-regulated kinase and ornithine decarboxylase.
Glioma
Proteolipid Protein 2 Overexpression Indicates Aggressive Tumor Behavior and Adverse Prognosis in Human Gliomas.
Glioma
Psychological Stress Up-Regulates CD147 Expression Through Beta-Arrestin1/ERK to Promote Proliferation and Invasiveness of Glioma Cells.
Glioma
PTEN gene transfer suppresses the invasive potential of human malignant gliomas by regulating cell invasion-related molecules.
Glioma
Quantitative analysis of matrix metalloproteinase-2 mRNA expression in central and peripheral regions of gliomas.
Glioma
Quercetin-induced downregulation of phospholipase D1 inhibits proliferation and invasion in U87 glioma cells.
Glioma
Radiosynthesis and Preliminary Biological Evaluation of 18F-Fluoropropionyl-Chlorotoxin as a Potential PET Tracer for Glioma Imaging.
Glioma
Rapid activation of matrix metalloproteinase-2 by glioma cells occurs through a posttranslational MT1-MMP-dependent mechanism.
Glioma
Regulation of matrix metalloproteinase-2 (MMP-2) by hepatocyte growth factor/scatter factor (HGF/SF) in human glioma cells: HGF/SF enhances MMP-2 expression and activation accompanying up-regulation of membrane type-1 MMP.
Glioma
regulation of the invasion and metastasis of human glioma cells by polypeptide N-acetylgalactosaminyltransferase 2.
Glioma
Relationship between expression of XRCC1 and tumor proliferation, migration, invasion, and angiogenesis in glioma.
Glioma
Remodeling of collagen matrix by human tumor cells requires activation and cell surface association of matrix metalloproteinase-2.
Glioma
RhoA regulates invasion of glioma cells via the c-Jun NH2-terminal kinase pathway under hypoxia.
Glioma
RNAi-mediated downregulation of MMP-2 activates the extrinsic apoptotic pathway in human glioma xenograft cells.
Glioma
Role of MMP-2 in the regulation of IL-6/Stat3 survival signaling via interaction with ?5?1 integrin in glioma.
Glioma
Rosiglitazone reduces cell invasiveness by inducing MKP-1 in human U87MG glioma cells.
Glioma
S-Adenosylhomocysteine Promotes the Invasion of C6 Glioma Cells via Increased Secretion of Matrix Metalloproteinase-2 in Murine Microglial BV2 Cells.
Glioma
S100B-p53 disengagement by pentamidine promotes apoptosis and inhibits cellular migration via aquaporin-4 and metalloproteinase-2 inhibition in C6 glioma cells.
Glioma
Scatter factor/hepatocyte growth factor gene transfer enhances glioma growth and angiogenesis in vivo.
Glioma
Secreted Frizzled-related proteins inhibit motility and promote growth of human malignant glioma cells.
Glioma
Secretion of matrix metalloproteinase-2 (72 kD gelatinase/type IV collagenase = gelatinase A) by malignant human glioma cell lines: implications for the growth and cellular invasion of the extracellular matrix.
Glioma
Serine protease inhibitor (SERPIN) B1 suppresses cell migration and invasion in glioma cells.
Glioma
Sevoflurane and thiopental preconditioning attenuates the migration and activity of MMP-2 in U87MG glioma cells.
Glioma
Sevoflurane inhibits migration and invasion of glioma cells via regulating miR-34a-5p/MMP-2 axis.
Glioma
Shikonin Inhibits the Migration and Invasion of Human Glioblastoma Cells by Targeting Phosphorylated ?-Catenin and Phosphorylated PI3K/Akt: A Potential Mechanism for the Anti-Glioma Efficacy of a Traditional Chinese Herbal Medicine.
Glioma
Simultaneous inhibition of glioma angiogenesis, cell proliferation, and invasion by a naturally occurring fragment of human metalloproteinase-2.
Glioma
Single minded 2-s (SIM2-s) gene is expressed in human GBM cells and involved in GBM invasion.
Glioma
SPARC upregulates MT1-MMP expression, MMP-2 activation, and the secretion and cleavage of galectin-3 in U87MG glioma cells.
Glioma
Specific matrix metalloproteinase profiles in the cerebrospinal fluid correlated with the presence of malignant astrocytomas, brain metastases, and carcinomatous meningitis.
Glioma
Sublethal dose of irradiation enhances invasion of malignant glioma cells through p53-MMP 2 pathway in U87MG mouse brain tumor model.
Glioma
Sublethal irradiation promotes migration and invasiveness of glioma cells: implications for radiotherapy of human glioblastoma.
Glioma
Suppression of cell invasion on human malignant glioma cell lines by a novel matrix-metalloproteinase inhibitor SI-27: in vitro study.
Glioma
Suppression of matrix metalloproteinase-2 gene expression and invasion in human glioma cells by MMAC/PTEN.
Glioma
Suppression of MMP-2 attenuates TNF-? induced NF-?B activation and leads to JNK mediated cell death in glioma.
Glioma
Synthetic emmprin peptides inhibit tumor cell-fibroblast interaction-stimulated upregulation of MMP-2 and tumor cell invasion.
Glioma
Tailoring Particle Size of Mesoporous Silica Nanosystem To Antagonize Glioblastoma and Overcome Blood-Brain Barrier.
Glioma
Targeting Gelatinases with a Near-Infrared Fluorescent Cyclic His-Try-Gly-Phe Peptide.
Glioma
Targeting the cytotoxicity of fusogenic membrane glycoproteins in gliomas through protease-substrate interaction.
Glioma
The combined use of EphA2/MMP-2 expression and MRI findings contributes to the determination of cerebral glioma grade.
Glioma
The effects of exogenous growth factors on matrix metalloproteinase secretion by human brain tumour cells.
Glioma
The expression and activation of matrix metalloproteinase-2 in rat brain after implantation of C6 rat glioma cells.
Glioma
The expression of matrix metalloproteinase-2 and -9 in human gliomas of different pathological grades.
Glioma
The farnesyltransferase inhibitor R115777 reduces hypoxia and matrix metalloproteinase 2 expression in human glioma xenograft.
Glioma
The impact of a chlorotoxin-modified liposome system on receptor MMP-2 and the receptor-associated protein ClC-3.
Glioma
The Impact of MMP-2 and Its Specific Inhibitor TIMP-2 Expression on the WHO Grade and Prognosis of Gliomas in Chinese Population: a Meta-Analysis.
Glioma
The mechanical and pharmacological regulation of glioblastoma cell migration in 3D matrices.
Glioma
The transcription factors Sp1, Sp3, and AP-2 are required for constitutive matrix metalloproteinase-2 gene expression in astroglioma cells.
Glioma
TNF-? mediated MEK-ERK signaling in invasion with putative network involving NF-?B and STAT-6: a new perspective in glioma.
Glioma
Tricetin suppresses the migration/invasion of human glioblastoma multiforme cells by inhibiting matrix metalloproteinase-2 through modulation of the expression and transcriptional activity of specificity protein 1.
Glioma
Tumor cell invasion through matrigel is regulated by activated matrix metalloproteinase-2.
Glioma
Tumor-suppressive function of long noncoding RNA MALAT1 in glioma cells by downregulation of MMP2 and inactivation of ERK/MAPK signaling.
Glioma
Up-regulation of angiopoietin-2, matrix metalloprotease-2, membrane type 1 metalloprotease, and laminin 5 gamma 2 correlates with the invasiveness of human glioma.
Glioma
Wnt-5a signaling is correlated with infiltrative activity in human glioma by inducing cellular migration and MMP-2.
Glioma
Zn(2+) induces apoptosis in human highly metastatic SHG-44 glioma cells, through inhibiting activity of the voltage-gated proton channel Hv1.
Glioma
[Expression of CD147 and MMP-2 in human gliomas and its correlations with prognosis]
Glioma
[Increased expression of gelatinases A and B, matrilysin and TIMP-1 genes in human malignant gliomas ]
Glioma
[Isoliquiritigenin can inhibit migration and invasion of human glioma stem cells by down-regulating matrix metalloproteinases].
Glioma
[The anti-cancer effect of ZR30 protein via targeting extracellular signal proteins of different cell subpopulations of glioma].
Gliosarcoma
Captopril inhibits Matrix Metalloproteinase-2 and extends survival as a temozolomide adjuvant in an intracranial gliosarcoma model.
Gliosarcoma
Transcriptional Factors for Epithelial-Mesenchymal Transition Are Associated with Mesenchymal Differentiation in Gliosarcoma.
Glomerulonephritis
Angiotensin-converting enzyme inhibition but not angiotensin II receptor blockade regulates matrix metalloproteinase activity in patients with glomerulonephritis.
Glomerulonephritis
Enhanced expression of membrane type-1 matrix metalloproteinase in mesangial proliferative glomerulonephritis.
Glomerulonephritis
Expression of MMP-9 in mesangial cells and its changes in anti-GBM glomerulonephritis in WKY rats.
Glomerulonephritis
Gelatinase B (MMP-9) is not essential in the normal kidney and does not influence progression of renal disease in a mouse model of Alport syndrome.
Glomerulonephritis
Macrophage-derived MT1-MMP and increased MMP-2 activity are associated with glomerular damage in crescentic glomerulonephritis.
Glomerulonephritis
Renal expression of matrix metalloproteinases in human ANCA-associated glomerulonephritis.
Glomerulonephritis
Specific changes in plasma concentrations of matrix metalloproteinase-2 and -9, TIMP-1 and TGF-beta1 in patients with distinct types of primary glomerulonephritis.
Glomerulonephritis
Structural characterization of the mesangial cell type IV collagenase and enhanced expression in a model of immune complex-mediated glomerulonephritis.
Glomerulonephritis
Transforming growth factor-beta 1 stimulates glomerular mesangial cell synthesis of the 72-kd type IV collagenase.
Glomerulonephritis
Treatment of experimental immune complex glomerulonephritis by sodium alginate.
Glomerulonephritis, IGA
Differential glomerular immunoexpression of matrix metalloproteinases MMP-2 and MMP-9 in idiopathic IgA nephropathy and Schoenlein-Henoch nephritis.
Glomerulonephritis, Membranous
Changes in serum concentrations of matrix metalloproteinases, tissue inhibitors of metalloproteinases and type IV collagen in patients with various types of glomerulonephritis.
Glomerulonephritis, Membranous
Matrix metalloproteinase-2, matrix metalloproteinase-9, and tissue inhibitor of metalloproteinase-1 in the peripheral blood of patients with various glomerular diseases and their implication in pathogenetic lesions: study based on an enzyme-linked assay and immunohistochemical staining.
Glomerulosclerosis, Focal Segmental
Distinct metalloproteinase excretion patterns in focal segmental glomerulosclerosis.
Glucose Intolerance
Serum levels of matrix metalloproteinases MMP-2 and MMP-9 and their inhibitors in women with glucose intolerance in pregnancy and normal controls.
Glucose Metabolism Disorders
Soluble P-selectin and matrix metalloproteinase 2 levels are elevated in patients with diastolic dysfunction independent of glucose metabolism disorder or coronary artery disease.
Granuloma
A comparative study of osteopontin and MMP-2 protein expression in peripheral and central giant cell granuloma of the jaws.
Granuloma
Association between bacteria occurring in the apical canal system and expression of bone-resorbing mediators and matrix metalloproteinases in apical periodontitis.
Granuloma
Continuous recruitment, co-expression of tumour necrosis factor-alpha and matrix metalloproteinases, and apoptosis of macrophages in gout tophi.
Granuloma
Cryptococcus neoformans pulmonary granuloma formation is associated with matrix metalloproteinase-2 expression.
Granuloma
Cytokines, MMP-2, and MMP-9 levels in patients with a solitary cysticercus granuloma.
Granuloma
Doxycycline hyclate: A schistosomicidal agent in vitro with immunomodulatory potential on granulomatous inflammation in vivo.
Granuloma
Expression of metalloproteinases (MMP-1, MMP-2, and MMP-9) and their inhibitors (TIMP-1 and TIMP-2) in schistosomal portal fibrosis.
Granuloma
Gene-expression analysis of matrix metalloproteinases 1 and 2 and their tissue inhibitors in chronic periapical inflammatory lesions.
Granuloma
Interstitial collagenase (MMP-1), gelatinase (MMP-2) and stromelysin (MMP-3) released by human fibroblasts cultured on acellular sarcoid granulomas (sarcoid matrix complex, SMC).
Granuloma
Matrix metalloproteinase-2 and -9 in the granulomatous fibrosis of rats infected with Angiostrongylus cantonensis.
Granuloma
Matrix metalloproteinase-2 and matrix metalloproteinase-9 in mice with ocular toxocariasis.
Granuloma
Matrix metalloproteinases and their tissue inhibitors in the lesions of cardiac and pulmonary sarcoidosis: an immunohistochemical study.
Granuloma
N-acetyl-cysteine decreases the matrix-degrading capacity of macrophage-derived foam cells: new target for antioxidant therapy?
Granuloma
Polymeric meshes induce zonal regulation of matrix metalloproteinase-2 gene expression by macrophages and fibroblasts.
Granuloma
Schwann cells producing matrix metalloproteinases under Mycobacterium leprae stimulation may play a role in the outcome of leprous neuropathy.
Granuloma, Giant Cell
A comparative study of osteopontin and MMP-2 protein expression in peripheral and central giant cell granuloma of the jaws.
Granulomatous Disease, Chronic
Activation of the endogenous metalloproteinase, gelatinase, by triggered human neutrophils.
Graves Disease
Elevated serum concentrations of metalloproteinases (MMP-2, MMP-9) and their inhibitors (TIMP-1, TIMP-2) in patients with Graves' orbitopathy.
Graves Disease
Type IV collagenase and immunostaining of type IV collagen in human thyroid tumors.
Graves Ophthalmopathy
[Serum gelatinases (MMP-2 and MMP-9) and VCAM-1 as a guideline in a therapeutic approach in Graves' ophthalmopathy.]
Guillain-Barre Syndrome
Matrix metalloproteinase-2 is involved in myelination of dorsal root ganglia neurons.
Guillain-Barre Syndrome
Matrix metalloproteinase-9 is increased and correlates with severity in Guillain-Barré syndrome.
Guillain-Barre Syndrome
Matrix metalloproteinases MMP-9 and MMP-7 are expressed in experimental autoimmune neuritis and the Guillain-Barré syndrome.
Hajdu-Cheney Syndrome
A novel matrix metalloproteinase 2 (MMP2) terminal hemopexin domain mutation in a family with multicentric osteolysis with nodulosis and arthritis with cardiac defects.
Hajdu-Cheney Syndrome
A novel mutation in the matrix metallopeptidase 2 coding gene associated with intrafamilial variability of multicentric osteolysis, nodulosis, and arthropathy.
Hajdu-Cheney Syndrome
Al-Aqeel Sewairi syndrome, a new autosomal recessive disorder with multicentric osteolysis, nodulosis and arthropathy. The first genetic defect of matrix metalloproteinase 2 gene.
Hajdu-Cheney Syndrome
Bisphosphonates in multicentric osteolysis, nodulosis and arthropathy (MONA) spectrum disorder - an alternative therapeutic approach.
Hajdu-Cheney Syndrome
Comparative Serum Analyses Identify Cytokines and Hormones Commonly Dysregulated as Well as Implicated in Promoting Osteolysis in MMP-2-Deficient Mice and Children.
Hajdu-Cheney Syndrome
Loss of MMP-2 in osteoblasts upregulates osteopontin and bone sialoprotein expression in a circuit regulating bone homeostasis.
Hajdu-Cheney Syndrome
Multicentric osteolysis with nodulosis and arthropathy (MONA) with cardiac malformation, mimicking polyarticular juvenile idiopathic arthritis: case report and literature review.
Hajdu-Cheney Syndrome
Multicentric Osteolysis, Nodulosis, and Arthropathy in two unrelated children with matrix metalloproteinase 2 variants: Genetic-skeletal correlations.
Hajdu-Cheney Syndrome
Mutation of the matrix metalloproteinase 2 gene (MMP2) causes a multicentric osteolysis and arthritis syndrome.
Hamartoma
Expression of matrix metalloproteinases and their endogenous tissue inhibitors in skin lesions from patients with tuberous sclerosis.
Head and Neck Neoplasms
Correlation between protein expression of PTEN in human pancreatic cancer and the proliferation, infiltration, metastasis and prognosis.
Head and Neck Neoplasms
Correlation of matrix metalloproteinase-2, -9, tissue inhibitor-1 of matrix metalloproteinase and CD44 variant 6 in head and neck cancer metastasis.
Head and Neck Neoplasms
Dehydrocrenatidine inhibits head and neck cancer cells invasion and migration by modulating JNK1/2 and ERK1/2 pathway and decreases MMP-2 expression.
Head and Neck Neoplasms
Epidermal growth factor-like ligands differentially up-regulate matrix metalloproteinase 9 in head and neck squamous carcinoma cells.
Head and Neck Neoplasms
Fibroblasts and extracellular matrix differently modulate MMP activation by primary and metastatic head and neck cancer cells.
Head and Neck Neoplasms
Genistein elicits pleiotropic molecular effects on head and neck cancer cells.
Head and Neck Neoplasms
Granulocyte colony-stimulating factor (G-CSF)-mediated signaling regulates type IV collagenase activity in head and neck cancer cells.
Head and Neck Neoplasms
Granulocyte-macrophage colony-stimulating factor upregulates matrix metalloproteinase-2 (MMP-2) and membrane type-1 MMP (MT1-MMP) in human head and neck cancer cells.
Head and Neck Neoplasms
Matrix metalloproteinase-2 as a target for head and neck cancer therapy.
Head and Neck Neoplasms
The role of genetic polymorphisms in the promoters of the matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 genes in head and neck cancer.
Heart Defects, Congenital
Matrix metalloproteinases as candidate biomarkers in adults with congenital heart disease.
Heart Defects, Congenital
Modulation of Systemic Metabolism by MMP-2: From MMP-2 Deficiency in Mice to MMP-2 Deficiency in Patients.
Heart Diseases
Acute actions and novel targets of matrix metalloproteinases in the heart and vasculature.
Heart Diseases
Angiotensin II downregulates ACE2-mediated enhancement of MMP-2 activity in human cardiofibroblasts.
Heart Diseases
Cardiac sarcomeric proteins: novel intracellular targets of matrix metalloproteinase-2 in heart disease.
Heart Diseases
Endogenous osteopontin induces myocardial CCL5 and MMP-2 activation that contributes to inflammation and cardiac remodeling in a mouse model of chronic Chagas heart disease.
Heart Diseases
Epigenetic Regulation of the N-Terminal Truncated Isoform of Matrix Metalloproteinase-2 (NTT-MMP-2) and Its Presence in Renal and Cardiac Diseases.
Heart Diseases
Intracellular targets of matrix metalloproteinase-2 in cardiac disease: rationale and therapeutic approaches.
Heart Diseases
Matrix metalloproteinase-2 functional promoter polymorphism G1575A is associated with elevated circulatory MMP-2 level and increased risk of cardiovascular disease in systemic lupus erythematosus patients.
Heart Diseases
Matrix Metalloproteinase-2 Mediates a Mechanism of Metabolic Cardioprotection Consisting of Negative Regulation of the Sterol Regulatory Element-Binding Protein-2/3-Hydroxy-3-Methylglutaryl-CoA Reductase Pathway in the Heart.
Heart Diseases
MMP-2 and TIMP-2 gene polymorphisms and susceptibility to atrial fibrillation in Chinese Han patients with hypertensive heart disease.
Heart Diseases
Targeted deletion of matrix metalloproteinase 2 ameliorates myocardial remodeling in mice with chronic pressure overload.
Heart Failure
Activation and modulation of 72kDa matrix metalloproteinase-2 by peroxynitrite and glutathione.
Heart Failure
Activation of matrix metalloproteinase dilates and decreases cardiac tensile strength.
Heart Failure
Admission plasma neutrophil gelatinase associated lipocalin (NGAL) predicts worsening renal function during hospitalization and post discharge outcome in patients with acute heart failure.
Heart Failure
Adrenoceptor blockade alters plasma gelatinase activity in patients with heart failure and MMP-9 promoter activity in a human cell line (ECV304).
Heart Failure
Associations Between Neutrophil Gelatinase Associated Lipocalin, Neutrophil-to-Lymphocyte Ratio, Atrial Fibrillation and Renal Dysfunction in Chronic Heart Failure.
Heart Failure
Atrial extracellular matrix remodeling and the maintenance of atrial fibrillation.
Heart Failure
Cardiac resynchronization therapy in patients with chronic heart failure is associated with anti-inflammatory and anti-remodeling effects.
Heart Failure
Cardiac transgenic matrix metalloproteinase-2 expression directly induces impaired contractility.
Heart Failure
Changes in activities of circulating MMP-2 and MMP-9 in patients suffering from heart failure in relation to gender, hypertension and treatment: a cross-sectional study.
Heart Failure
Changes of serum advanced glycation end products (AGEs), matrix metalloprotein-2 (MMP-2), and urinary microalbuminuria (mALB) in diabetic nephropathy and their predictive value for heart failure.
Heart Failure
Circulating matrix metalloproteinase-2 but not matrix metalloproteinase-3, matrix metalloproteinase-9, or tissue inhibitor of metalloproteinase-1 predicts outcome in patients with congestive heart failure.
Heart Failure
Circulating matrix metalloproteinase-2 is elevated in patients with congestive heart failure.
Heart Failure
Clinical significance of matrix metalloproteinase (MMP)-2 in patients with acute heart failure.
Heart Failure
Combination of Plasma Biomarkers and Clinical Data for the Detection of Myocardial Fibrosis or Aggravation of Heart Failure Symptoms in Heart Failure with Preserved Ejection Fraction Patients.
Heart Failure
Comparison between admission natriuretic peptides, NGAL and sST2 testing for the prediction of worsening renal function in patients with acutely decompensated heart failure.
Heart Failure
Comparison of levels of matrix metalloproteinase-2 and -3 in patients with ischemic cardiomyopathy versus nonischemic cardiomyopathy.
Heart Failure
Comparison of predictive value of NT-proBNP, sST2 and MMPs in heart failure patients with different ejection fractions.
Heart Failure
Cycloastragenol ameliorates experimental heart damage in rats by promoting myocardial autophagy via inhibition of AKT1-RPS6KB1 signaling.
Heart Failure
Differences in the association between behavior and neutrophil gelatinase-associated lipocalin in male and female rats after coronary artery ligation.
Heart Failure
Down-regulation of matrix metalloproteinase-9 (MMP-9) expression in the myocardium of congestive heart failure patients.
Heart Failure
Effect of atorvastatin on non-ischemic heart failure and matrix metalloproteinase-2 and 9 in rats.
Heart Failure
Effect of typhaneoside on ventricular remodeling and regulation of PI3K/Akt/mTOR pathway.
Heart Failure
Ethanol extract from Epimedium brevicornum attenuates left ventricular dysfunction and cardiac remodeling through down-regulating matrix metalloproteinase-2 and -9 activity and myocardial apoptosis in rats with congestive heart failure.
Heart Failure
Excessive activation of matrix metalloproteinases coincides with left ventricular remodeling during transition from hypertrophy to heart failure in hypertensive rats.
Heart Failure
Human cardiac fibroblast extracellular matrix remodeling: dual effects of tissue inhibitor of metalloproteinase-2.
Heart Failure
Hydrogen sulfide mitigates transition from compensatory hypertrophy to heart failure.
Heart Failure
Icariin attenuates cardiac remodelling through down-regulating myocardial apoptosis and matrix metalloproteinase activity in rats with congestive heart failure.
Heart Failure
Immediate administration of atorvastatin decreased the serum MMP-2 level and improved the prognosis for acute heart failure.
Heart Failure
Impact of metalloproteinases on left ventricular remodeling and heart failure events in patients with hypertrophic cardiomyopathy.
Heart Failure
Influence of Spironolactone on Matrix Metalloproteinase-2 in Acute Decompensated Heart Failure.
Heart Failure
Influence of spironolactone on matrix metalloproteinase-2 in acute decompensated heart failure.
Heart Failure
Inhibition of matrix metalloproteinase activity by ACE inhibitors prevents left ventricular remodeling in a rat model of heart failure.
Heart Failure
Levosimendan use reduces matrix metalloproteinase-2 in patients with decompensated heart failure.
Heart Failure
Long-term therapy with the acorn cardiac support device normalizes gene expression of growth factors and gelatinases in dogs with heart failure.
Heart Failure
Matrix metalloproteinase-2 and myocardial oxidative stress injury: beyond the matrix.
Heart Failure
Matrix metalloproteinase-2 mediates cytokine-induced myocardial contractile dysfunction.
Heart Failure
Matrix Metalloproteinase-2 Polymorphisms in Chronic Heart Failure: Relationship with Susceptibility and Long-Term Survival.
Heart Failure
Matrix Metalloproteinase-2 predicts mortality in patients with acute coronary syndrome.
Heart Failure
Matrix remodeling in experimental and human heart failure: a possible regulatory role for TIMP-3.
Heart Failure
Metalloproteinase expression is altered in cardiac and skeletal muscle in cancer cachexia.
Heart Failure
Metalloproteinases 2 and 9 are increased in plasma of patients with heart failure.
Heart Failure
Metalloproteinases-2 and -9 predict left ventricular remodeling after myocardial infarction.
Heart Failure
MMP-2/TIMP-2/TIMP-4 versus MMP-9/TIMP-3 in transition from compensatory hypertrophy and angiogenesis to decompensatory heart failure.
Heart Failure
Neurohormonal activation is associated with increased levels of plasma matrix metalloproteinase-2 in human heart failure.
Heart Failure
Plasma Biomarkers Reflecting Profibrotic Processes in Heart Failure With a Preserved Ejection Fraction: Data From the Prospective Comparison of ARNI With ARB on Management of Heart Failure With Preserved Ejection Fraction Study.
Heart Failure
Plasma concentrations of matrix metalloproteinase-2, tissue inhibitor of metalloproteinase-1 and osteopontin reflect severity of heart failure in DOCA-salt hypertensive rat.
Heart Failure
Polymorphisms of MMP-2 gene are associated with systolic heart failure prognosis.
Heart Failure
Polymorphisms of MMP-2 Gene are Associated With Systolic Heart Failure Risk in Han Chinese.
Heart Failure
Prolargin and matrix metalloproteinase-2 in heart failure after heart transplantation and their association with haemodynamics.
Heart Failure
Quantification of diffuse myocardial fibrosis using CMR extracellular volume fraction and serum biomarkers of collagen turnover with histologic quantification as standard of reference.
Heart Failure
Relationship Between Myocardial Redox State and Matrix Metalloproteinase Activity in Patients on Left Ventricular Assist Device Support.
Heart Failure
Selective disruption of MMP-2 gene exacerbates myocardial inflammation and dysfunction in mice with cytokine-induced cardiomyopathy.
Heart Failure
Serum MMP-9 activity as a diagnosing marker for the developing heart failure of post MI patients.
Heart Failure
Targeted deletion of MMP-2 attenuates early LV rupture and late remodeling after experimental myocardial infarction.
Heart Failure
Temporal regulation of extracellular matrix components in transition from compensatory hypertrophy to decompensatory heart failure.
Heart Failure
The influence of oral copper-methionine on matrix metalloproteinase-2 gene expression and activation in right-sided heart failure induced by cold temperature: A broiler chicken perspective.
Heart Failure
TIMP-2 mutant decreases MMP-2 activity and augments pressure overload induced LV dysfunction and heart failure.
Heart Failure
Two MMP-2 promoter polymorphisms (-790T/G and -735C/T) in chronic heart failure.
Heart Failure
Urinary neutrophil gelatinase associated lipocalin (NGAL), a marker of tubular damage, is increased in patients with chronic heart failure.
Heart Failure
Water-soluble alkaloids extracted from Aconiti Radix lateralis praeparata protect against chronic heart failure in rats via a calcium signaling pathway.
Heart Failure
[Effects of angiotensin II receptor antagonism on matrix metalloproteinases and fibronectin in rats with experimental myocardial infarction]
Heart Failure
[Effects of bone marrow mesenchymal stem cells transplantation on heart function and ventricular remodeling in rats with isoproterenol-induced congestive heart failure]
Heart Failure
[Matrix metalloproteinases and their inhibitors in lung cancer with malignant pleural effusion]
Heart Failure, Systolic
A novel intracellular isoform of matrix metalloproteinase-2 induced by oxidative stress activates innate immunity.
Heart Failure, Systolic
N-terminal truncated intracellular matrix metalloproteinase-2 induces cardiomyocyte hypertrophy, inflammation and systolic heart failure.
Heart Failure, Systolic
Polymorphisms of MMP-2 gene are associated with systolic heart failure prognosis.
Heart Failure, Systolic
Polymorphisms of MMP-2 Gene are Associated With Systolic Heart Failure Risk in Han Chinese.
Heart Rupture
Apoptosis inhibitor of macrophage depletion decreased M1 macrophage accumulation and the incidence of cardiac rupture after myocardial infarction in mice.
Heart Rupture
Targeted deletion of MMP-2 attenuates early LV rupture and late remodeling after experimental myocardial infarction.
Heart Rupture
Targeted deletion or pharmacological inhibition of MMP-2 prevents cardiac rupture after myocardial infarction in mice.
Heart Rupture
Temporal changes in matrix metalloproteinase expression and inflammatory response associated with cardiac rupture after myocardial infarction in mice.
Heart Rupture
Toll-like receptor 7 deficiency promotes survival and reduces adverse left ventricular remodelling after myocardial infarction.
Heart Rupture
Trimetazidine suppresses oxidative stress, inhibits MMP-2 and MMP-9 expression, and prevents cardiac rupture in mice with myocardial infarction.
Heart Rupture
Twinkle overexpression prevents cardiac rupture after myocardial infarction by alleviating impaired mitochondrial biogenesis.
Heart Septal Defects, Ventricular
Circulating matrix metalloproteinase-2 and -9 enzyme activities in the children with ventricular septal defect.
HELLP Syndrome
Placental expression of proteases and their inhibitors in patients with HELLP syndrome.
Hemangioma
Activation of matrix metalloproteinase (MMP)-2 by membrane type 1-MMP and abnormal immunolocalization of the basement membrane components laminin and type IV collagen in canine spontaneous hemangiosarcomas.
Hemangioma
Evaluation of Effect of Propranolol on Serum Vascular Endothelial Growth Factor and Tissue Inhibitor of Metalloproteinase-2 Levels in Infantile Hemangioma.
Hemangioma
Inhibition of matrix metalloproteinases by over-expression of tissue inhibitor of metalloproteinase-2 inhibits the growth of experimental hemangiomas.
Hemangioma
Serum cytokine profiles in infants with infantile hemangiomas on oral propranolol treatment: VEGF and bFGF, potential biomarkers predicting clinical outcomes.
Hemangioma
[Study the effect of antisense MMP-2 by transfection of ad-aMMP-2 on vascular endothelial cells from human proferating hemangiomas in vitro]
Hemangioma, Cavernous, Central Nervous System
Expression of matrix metalloproteinases (MMPs) and tissue inhibitor of metalloproteinase (TIMP) in cerebral cavernous malformations: immunohistochemical analysis of MMP-2, -9 and TIMP-2.
Hemangiosarcoma
Inhibition of endoglin exerts anti-tumor effects through the regulation of non-Smad TGF-? signaling in angiosarcoma.
Hematologic Neoplasms
Association of MMP-2 (-1306 C>T), MMP-9 (-1562 C>T) Gene Polymorphism and the Formation of the Hematological Malignancies.
Hematologic Neoplasms
Inhibitors of gelatinases (MMP-2 and MMP-9) for the management of hematological malignancies.
Hematologic Neoplasms
Is dual inhibition of metalloenzymes HDAC-8 and MMP-2 a potential pharmacological target to combat hematological malignancies?
Hematologic Neoplasms
Secretion and Expression of Matrix Metalloproteinase-2 and 9 from Bone Marrow Mononuclear Cells in Myelodysplastic Syndrome and Acute Myeloid Leukemia.
Hematologic Neoplasms
[Effect of As(2)O(3) on Expressions of COX-2 and Matrix Metalloproteinases in SGC7901 and K562 Cells.]
Hematoma, Subdural, Chronic
Role of MMP-2, MMP-9 and VEGF in the development of chronic subdural hematoma.
Hematoma, Subdural, Chronic
[Role of matrix metalloproteinase in transformation of subdural effusion into chronic subdural hematoma]
Hemochromatosis
Elevated serum type IV collagen: a sensitive indicator of the presence of cirrhosis in haemochromatosis.
Hemochromatosis
Evidence for altered hepatic matrix degradation in genetic haemochromatosis.
Hemorrhagic Stroke
Different expression of ubiquitin C-terminal hydrolase-L1 and ?II-spectrin in ischemic and hemorrhagic stroke: Potential biomarkers in diagnosis.
Hemorrhagic Stroke
Increased brain expression of matrix metalloproteinase-9 after ischemic and hemorrhagic human stroke.
Hemorrhagic Stroke
Intranasal delivery of hypoxia-preconditioned bone marrow-derived mesenchymal stem cells enhanced regenerative effects after intracerebral hemorrhagic stroke in mice.
Hemorrhagic Stroke
MMP-2/MMP-9 plasma level and brain expression in Cerebral Amyloid Angiopathy-associated hemorrhagic stroke.
Hepatic Veno-Occlusive Disease
Sinusoidal obstruction syndrome (veno-occlusive disease) in the rat is prevented by matrix metalloproteinase inhibition.
Hepatitis
Clinical significance of serum matrix metalloproteinases and tissue inhibitors of metalloproteinases in chronic liver disease.
Hepatitis
Correlation between plasma levels of matrix metalloproteinase (MMP)-9 /MMP-2 ratio and alpha-fetoproteins in chronic hepatitis carrying hepatitis B virus.
Hepatitis
Elevated MTSS1 expression associated with metastasis and poor prognosis of residual hepatitis B-related hepatocellular carcinoma.
Hepatitis
Expression and cDNA sequence of matrix metalloproteinase-2 (MMP-2) in a mammalian model of human disease processes: Tupaia belangeri.
Hepatitis B
Correlation between plasma levels of matrix metalloproteinase (MMP)-9 /MMP-2 ratio and alpha-fetoproteins in chronic hepatitis carrying hepatitis B virus.
Hepatitis B
Evaluation of serum matrix metalloproteinase (MMP)-9 to MMP-2 ratio as a biomarker in hepatocellular carcinoma.
Hepatitis B, Chronic
Clinical utility of serum matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 concentrations in the assessment of liver fibrosis due to chronic hepatitis B.
Hepatitis B, Chronic
Differential expression of matrix metalloproteinases in viral and non-viral chronic liver diseases.
Hepatitis B, Chronic
Evaluation of serum matrix metalloproteinase (MMP)-9 to MMP-2 ratio as a biomarker in hepatocellular carcinoma.
Hepatitis B, Chronic
Matrix metalloproteinases and their tissue inhibitors in children with chronic hepatitis B treated with lamivudine.
Hepatitis B, Chronic
Significant differences in serum activities of matrix metalloproteinase-2 and -9 between HCV- and HBV-infected patients and carriers.
Hepatitis B, Chronic
The Clinical Significance of Serum Apoptotic Cytokeratin 18 Neoepitope M30 (CK-18 M30) and Matrix Metalloproteinase 2 (MMP-2) Levels in Chronic Hepatitis B Patients with Cirrhosis.
Hepatitis B, Chronic
[Effect of oxymatrine on serum matrix metalloproteinase-2 and its inhibitor in patients with chronic hepatitis B and liver cirrhosis]
Hepatitis C
Binding of hepatitis C virus envelope protein E2 to CD81 up-regulates matrix metalloproteinase-2 in human hepatic stellate cells.
Hepatitis C
Diagnostic potential of circulating TIMP-1 and MMP-2 as markers of liver fibrosis in patients with chronic hepatitis C.
Hepatitis C
Differential expression of matrix metalloproteinases in viral and non-viral chronic liver diseases.
Hepatitis C
Expression of matrix metalloproteinase-2 and -9 and their inhibitors in peripheral blood cells of patients with chronic hepatitis C.
Hepatitis C
Hepatitis C virus activates Bcl-2 and MMP-2 expression through multiple cellular signaling pathways.
Hepatitis C
Is neutrophil gelatinase associated lipocalin useful in hepatitis C virus infection?
Hepatitis C, Chronic
Circulating matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-1 as serum markers of fibrosis in patients with chronic hepatitis C. Relationship to interferon response.
Hepatitis C, Chronic
Clinical role of serum and tissue matrix metalloprotease-9 expression in chronic HCV patients treated with pegylated IFN-alpha2b and ribavirin.
Hepatitis C, Chronic
Diagnostic potential of circulating TIMP-1 and MMP-2 as markers of liver fibrosis in patients with chronic hepatitis C.
Hepatitis C, Chronic
Diagnostic potential of serum matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-1 as non-invasive markers of hepatic fibrosis in patients with HCV related chronic liver disease.
Hepatitis C, Chronic
Diagnostic value of serum markers of connective tissue turnover for predicting histological staging and grading in patients with chronic hepatitis C.
Hepatitis C, Chronic
Effect of antiviral therapy on markers of fibrogenesis in patients with chronic hepatitis C.
Hepatitis C, Chronic
Effects of interferon plus ribavirin treatment on NF-kappaB, TGF-beta1, and metalloproteinase activity in chronic hepatitis C.
Hepatitis C, Chronic
Expression of matrix metalloproteinase-2 and -9 and their inhibitors in peripheral blood cells of patients with chronic hepatitis C.
Hepatitis C, Chronic
Increased intrahepatic cyclooxygenase 2, matrix metalloproteinase 2, and matrix metalloproteinase 9 expression is associated with progressive liver disease in chronic hepatitis C virus infection: role of viral core and NS5A proteins.
Hepatitis C, Chronic
Plasma levels of matrix metalloproteinase-2 (MMP-2) and tissue inhibitors of metalloproteinases -1 and -2 (TIMP-1 and TIMP-2) as noninvasive markers of liver disease in chronic hepatitis C: comparison using ROC analysis.
Hepatitis C, Chronic
Significance of serum matrix metalloproteinases and their inhibitors on the antifibrogenetic effect of interferon-alfa in chronic hepatitis C patients.
Hepatitis, Chronic
Clinical significance of serum matrix metalloproteinases and tissue inhibitors of metalloproteinases in chronic liver disease.
Hepatitis, Chronic
Clinical usefulness of serum matrix metalloproteinase-2 concentration in patients with chronic viral liver disease.
Hepatitis, Chronic
Evaluation of serum matrix metalloproteinase (MMP)-9 to MMP-2 ratio as a biomarker in hepatocellular carcinoma.
Hepatitis, Chronic
Expression of matrix metalloproteinase-2 and -9 and their inhibitors in peripheral blood cells of patients with chronic hepatitis C.
Hepatitis, Chronic
Overexpression of matrix metalloproteinase 9 gene in hepatocellular carcinoma with invasive potential.
Hepatitis, Chronic
Serum levels of tissue inhibitor of metalloproteinases-2 and of precursor form of matrix metalloproteinase-2 in patients with liver disease.
Hepatitis, Chronic
Usefulness of non-invasive markers for predicting liver cirrhosis in patients with chronic hepatitis B.
Hepatitis, Chronic
[Clinical usefulness of plasma activities of gelatinase (matrix metalloproteinase-2 and 9) in chronic liver disease]
Hepatitis, Chronic
[Expression of matrix metalloproteinase-2 and its tissue inhibitor in liver tissue of patients with chronic hepatitis and cirrhosis]
Hepatopulmonary Syndrome
Correlations of MMP-2 and MMP-9 gene polymorphisms with the risk of hepatopulmonary syndrome in cirrhotic patients: A case-control study.
Herpes Zoster
Caspase-1 Inhibitor Prevents Neurogenic Pulmonary Edema After Subarachnoid Hemorrhage in Mice.
Herpes Zoster
Effects of Kaixinjieyu, a Chinese herbal medicine preparation, on neurovascular unit dysfunction in rats with vascular depression.
Herpes Zoster
Sperm Cohort-Specific Zinc Signature Acquisition and Capacitation-Induced Zinc Flux Regulate Sperm-Oviduct and Sperm-Zona Pellucida Interactions.
Herpes Zoster
Sperm matrix metalloproteinase-2 activity increased in pregnant couples treated with intrauterine insemination: a prospective case control study.
Herpes Zoster
T cell-mediated biliary epithelial-to-mesenchymal transition in liver allograft rejection.
Hidradenitis Suppurativa
Tumour Necrosis Factor-alpha and Matrix Metalloproteinase-2 are Expressed Strongly in Hidradenitis Suppurativa.
Hirsutism
Comparative Serum Analyses Identify Cytokines and Hormones Commonly Dysregulated as Well as Implicated in Promoting Osteolysis in MMP-2-Deficient Mice and Children.
Histiocytoma, Benign Fibrous
Expression of 72 kilodalton and 92 kilodalton type IV collagenase in malignant fibrous histiocytomas and dermatofibromas.
Histiocytoma, Benign Fibrous
Expression of MMP-2, MMP-9 and MMP-11 in dermatofibroma and dermatofibrosarcoma protuberans.
Histiocytoma, Benign Fibrous
Immunohistochemical study of membrane type-matrix metalloproteinases (MT-MMPs) and matrix metalloproteinase-2 (MMP-2) in dermatofibroma and malignant fibrous histiocytoma.
Histiocytoma, Malignant Fibrous
Expression of 72 kilodalton and 92 kilodalton type IV collagenase in malignant fibrous histiocytomas and dermatofibromas.
Histiocytoma, Malignant Fibrous
Immunohistochemical study of membrane type-matrix metalloproteinases (MT-MMPs) and matrix metalloproteinase-2 (MMP-2) in dermatofibroma and malignant fibrous histiocytoma.
Histiocytoma, Malignant Fibrous
Malignant Fibrous Histiocytoma, Aggressive Fibromatosis and Benign Fibrous Tumors Express mRNA for the Metalloproteinase Inducer EMMPRIN and the Metalloproteinases MMP-2 and MT1-MMP.
HIV Infections
72-kDa and 92-kDa gelatinases in saliva of patients with human immunodeficiency virus infection.
HIV Infections
An evaluation of neurocognitive status and markers of immune activation as predictors of time to death in advanced HIV infection.
HIV Infections
Effects of norepinephrine, HIV type 1 infection, and leukocyte interactions with endothelial cells on the expression of matrix metalloproteinases.
HIV Infections
Evaluation of HIV RNA and markers of immune activation as predictors of HIV-associated dementia.
HIV Infections
HIV-induced metalloproteinase processing of the chemokine stromal cell derived factor-1 causes neurodegeneration.
HIV Infections
Matrix metalloproteinase levels in early HIV infection and relation to in vivo brain status.
HIV Infections
Matrix metalloproteinase-2 on activated platelets triggers endothelial PAR-1 initiating atherosclerosis.
HIV Infections
Modulations of 92kDa gelatinase B and its inhibitors are associated with HIV-1 infection in human macrophage cultures.
Hodgkin Disease
Diverse role of MMP-2 and MMP-9 in the clinicopathological behavior of Hodgkin's lymphoma.
Hodgkin Disease
Immunohistochemical expression of angiogenic cytokines in childhood Hodgkin lymphoma.
Hodgkin Disease
Plasma MMP-2-TIMP-2 complex levels measured during follow-up predict a risk of relapse in patients with malignant lymphoma.
Hodgkin Disease
Prognostic value of matrix metalloproteinases (MMP-2 and MMP-9) in Hodgkin's and non-Hodgkin's lymphoma.
HTLV-I Infections
Expression of metalloproteinase-2 (gelatinase A) in labial salivary glands of patients with Sjögren's syndrome with HTLV-I infection.
HTLV-I Infections
Human T-cell leukemia virus type I Tax transactivates the matrix metalloproteinase-9 gene: potential role in mediating adult T-cell leukemia invasiveness.
Hyaline Membrane Disease
Gelatinase activities in the airways of premature infants and development of bronchopulmonary dysplasia.
Hydatidiform Mole
Expression of matrix metalloproteinase-2 and mutant p53 is increased in hydatidiform mole as compared with normal placenta.
Hydatidiform Mole
Reduced expression of tissue inhibitor of metalloproteinase (TIMP)-2 in gestational trophoblastic diseases.
Hydatidiform Mole
[MMP-2/TIMP-2 expression in the trophoblasts of patients with gestational trophoblastic disease]
Hydatidiform Mole
[Prediction of malignant transformation of hydatidiform mole by mRNA determination of matrix metalloproteinases and tissue inhibitor of metalloproteinases]
Hydatidiform Mole, Invasive
[MMP-2/TIMP-2 expression in the trophoblasts of patients with gestational trophoblastic disease]
Hydronephrosis
Can serum Neutrophil Gelatinase Associated Lipocalin and Kidney Injury Molecule-1 help in decision making for surgery in antenatally dedected hydronephrosis.
Hydronephrosis
Matrix Metalloproteinase-2 Knockout and Heterozygote Mice Are Protected from Hydronephrosis and Kidney Fibrosis after Unilateral Ureteral Obstruction.
Hydronephrosis
Selected Metal Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases as Potential Biomarkers for Tubulointerstitial Fibrosis in Children with Unilateral Hydronephrosis.
Hyperalgesia
Analgesic Effect of Methane Rich Saline in a Rat Model of Chronic Inflammatory Pain.
Hyperalgesia
Astrocyte contributes to pain development via MMP2-JNK1/2 signaling in a mouse model of complex regional pain syndrome.
Hyperalgesia
DNMT3b SUMOylation Mediated MMP-2 Upregulation Contribute to Paclitaxel Induced Neuropathic Pain.
Hyperalgesia
Effect of a Novel, Orally Active Matrix Metalloproteinase-2 and -9 Inhibitor in Spinal and Trigeminal Rat Models of Neuropathic Pain.
Hyperalgesia
Functional interplay between gelatinases and hyperalgesia in endotoxin-induced localized inflammatory pain.
Hyperalgesia
Growth hormone releasing hormone reverses endotoxin-induced localized inflammatory hyperalgesia without reducing the upregulated cytokines, nerve growth factor and gelatinase activity.
Hyperalgesia
NOV/CCN3 attenuates inflammatory pain through regulation of matrix metalloproteinases-2 and -9.
Hypercholesterolemia
Management of cardiac fibrosis in diabetic rats; the role of peroxisome proliferator activated receptor gamma (PPAR-gamma) and calcium channel blockers (CCBs).
Hypercholesterolemia
Salvianolic acid B attenuates MMP-2 and MMP-9 expression in vivo in apolipoprotein-E-deficient mouse aorta and in vitro in LPS-treated human aortic smooth muscle cells.
Hyperglycemia
Defining the Regulated Secreted Proteome of Rodent Adipocytes upon the Induction of Insulin Resistance.
Hyperglycemia
Do different bariatric surgical procedures influence plasma levels of matrix metalloproteinase-2, -7, and -9 among patients with type 2 diabetes mellitus?
Hyperglycemia
Enhanced expression of two discrete isoforms of matrix metalloproteinase-2 in experimental and human diabetic nephropathy.
Hyperglycemia
Hyperglycemia-Induced Modulation of the Physiognomy and Angiogenic Potential of Fibroblasts Mediated by Matrix Metalloproteinase-2: Implications for Venous Stenosis Formation Associated with Hemodialysis Vascular Access in Diabetic Milieu.
Hyperglycemia
Hyperglycemic condition during puberty increases collagen fibers deposition in the prostatic stroma and reduces MMP-2 activity.
Hyperglycemia
Insulin-dependent activation of endothelial nitric oxide synthase is impaired by O-linked glycosylation modification of signaling proteins in human coronary endothelial cells.
Hyperglycemia
Lercanidipine decreases vascular matrix metalloproteinase-2 activity and protects against vascular dysfunction in diabetic rats.
Hyperglycemia
Management of cardiac fibrosis in diabetic rats; the role of peroxisome proliferator activated receptor gamma (PPAR-gamma) and calcium channel blockers (CCBs).
Hyperglycemia
Rice bran protein hydrolysates reduce arterial stiffening, vascular remodeling and oxidative stress in rats fed a high-carbohydrate and high-fat diet.
Hyperglycemia
Role of TSPO/VDAC1 Upregulation and Matrix Metalloproteinase-2 Localization in the Dysfunctional Myocardium of Hyperglycaemic Rats.
Hyperhomocysteinemia
Homocysteine enriched diet leads to prolonged QT interval and reduced left ventricular performance in telemetric monitored mice.
Hyperhomocysteinemia
Induction of oxidative stress by homocyst(e)ine impairs endothelial function.
Hyperinsulinism
In vivo effects of insulin and free fatty acids on matrix metalloproteinases in rat aorta.
Hyperlipidemias
Hyperlipidemia attenuates the infarct size-limiting effect of ischemic preconditioning: role of matrix metalloproteinase-2 inhibition.
Hyperostosis
Possible role of matrix metalloproteinases (MMPs) in hyperostosis of intracranial meningiomas.
Hypersensitivity
Expression of matrix metalloproteinase-9 and -2 in pediatric chronic otitis media with effusion.
Hypertension
Adiponectin as an Independent Predictor of Left Ventricular Hypertrophy in Nondiabetic Patients With Hypertension.
Hypertension
Age- and Phenotype-Dependent Changes in Circulating MMP-2 and MMP-9 Activities in Normotensive and Hypertensive Rats.
Hypertension
Aldosterone mediates angiotensin II-induced interstitial cardiac fibrosis via a Nox2-containing NADPH oxidase.
Hypertension
Alterations in vascular matrix metalloproteinase due to ageing and chronic hypertension: effects of endothelin receptor blockade.
Hypertension
Antioxidant effect of doxycycline decreases MMP activity and blood pressure in SHR.
Hypertension
Antioxidant treatment reduces matrix metalloproteinase-2-induced vascular changes in renovascular hypertension.
Hypertension
Atorvastatin and sildenafil decrease vascular TGF-? levels and MMP-2 activity and ameliorate arterial remodeling in a model of renovascular hypertension.
Hypertension
Cell-specific and endothelium-dependent regulations of matrix metalloproteinase-2 in rat aorta.
Hypertension
Changes in activities of circulating MMP-2 and MMP-9 in patients suffering from heart failure in relation to gender, hypertension and treatment: a cross-sectional study.
Hypertension
Changes of serum advanced glycation end products (AGEs), matrix metalloprotein-2 (MMP-2), and urinary microalbuminuria (mALB) in diabetic nephropathy and their predictive value for heart failure.
Hypertension
Common matrix metalloproteinase 2 gene haplotypes may modulate left ventricular remodelling in hypertensive patients.
Hypertension
Comparative study on antioxidant effects and vascular matrix metalloproteinase-2 downregulation by dihydropyridines in renovascular hypertension.
Hypertension
Consistent Alterations of Circulating Matrix Metalloproteinases Levels in Untreated Hypertensives and in Spontaneously Hypertensive Rats: A Relevant Pharmacological Target.
Hypertension
Does Arterial Hypertension Affect Plasma Levels of Matrix Metalloproteinases and Their Tissue Inhibitors in Patients with Stable Coronary Artery Disease? A Preliminary Study.
Hypertension
Downregulation of vascular matrix metalloproteinase inducer and activator proteins in hypertensive patients.
Hypertension
Dynamics of Distribution of Capillaries with Matrix Metalloproteinase-2 and Its Tissue Inhibitor in Rat Brain during Development of Experimental Hypertension.
Hypertension
Estrogen deficiency-induced alterations of vascular MMP-2, MT1-MMP, and TIMP-2 in ovariectomized rats.
Hypertension
Euterpe oleracea Mart.-derived polyphenols prevent endothelial dysfunction and vascular structural changes in renovascular hypertensive rats: role of oxidative stress.
Hypertension
Evaluation of metalloproteinases 2 and 9 and their inhibitors in physiologic and pre-eclamptic pregnancy.
Hypertension
Evidence of early involvement of matrix metalloproteinase-2 in lead-induced hypertension.
Hypertension
Excessive activation of matrix metalloproteinases coincides with left ventricular remodeling during transition from hypertrophy to heart failure in hypertensive rats.
Hypertension
Exogenous l-arginine reduces matrix metalloproteinase-2 and -9 activities and oxidative stress in patients with hypertension.
Hypertension
Expression and response to Angiotensin-converting enzyme inhibition of matrix metalloproteinases 2 and 9 in renal glomerular damage in young transgenic rats with Renin-dependent hypertension.
Hypertension
Expression of matrix metalloproteinases MMP-2 and MMP-9 is altered during nephrogenesis in fetuses from diabetic rats.
Hypertension
Expression of the recessive glomerulosclerosis gene Mpv17 regulates MMP-2 expression in fibroblasts, the kidney, and the inner ear of mice.
Hypertension
Hypertension, augmented activity of matrix metalloproteinases-2 and -9 and angiogenic imbalance in hypertensive pregnancy are attenuated by doxycycline.
Hypertension
Hypertensive vascular remodeling was inhibited by Xuezhikang through the regulation of Fibulin-3 and MMPs in spontaneously hypertensive rats.
Hypertension
Impact of Biomarkers of Inflammation and Extracellular Matrix Turnover on the Outcome of Atrial Fibrillation Ablation: Importance of Matrix Matalloproteinase-2 as a Predictor of Atrial Fibrillation Recurrence.
Hypertension
Impact of matrix metalloproteinase-2 levels on long-term outcome following pharmacological or electrical cardioversion in patients with atrial fibrillation.
Hypertension
Increased Circulating Tissue Inhibitor of Metalloproteinase-2 Is Associated With Resistant Hypertension.
Hypertension
Increased Matrix Metalloproteinase 2 Activity in the Human Internal Mammary Artery Is Associated with Ageing, Hypertension, Diabetes and Kidney Dysfunction.
Hypertension
Inhibition of matrix metalloproteinase-2 improves endothelial function and prevents hypertension in insulin resistant rats.
Hypertension
Involvement of matrix metalloproteinase-2 in medial hypertrophy of pulmonary arterioles in broiler chickens with pulmonary arterial hypertension.
Hypertension
Lercanidipine reduces matrix metalloproteinase-2 activity and reverses vascular dysfunction in renovascular hypertensive rats.
Hypertension
Management of cardiac fibrosis in diabetic rats; the role of peroxisome proliferator activated receptor gamma (PPAR-gamma) and calcium channel blockers (CCBs).
Hypertension
Matrix metalloproteinase (MMP)-2 activation by oxidative stress decreases aortic calponin-1 levels during hypertrophic remodeling in early hypertension.
Hypertension
Matrix metalloproteinase (MMP)-2 decreases calponin-1 levels and contributes to arterial remodeling in early hypertension.
Hypertension
Matrix metalloproteinase -2, -9 and arterial stiffness in children and adolescents: The role of chronic kidney disease, diabetes, and hypertension.
Hypertension
Matrix Metalloproteinase 2 as a Potential Mediator of Vascular Smooth Muscle Cell Migration and Chronic Vascular Remodeling in Hypertension.
Hypertension
Matrix metalloproteinase 7 in diagnosis and differentiation of pulmonary arterial hypertension.
Hypertension
Matrix metalloproteinase 9 polymorphisms and systemic lupus erythematosus: correlation with systemic inflammatory markers and oxidative stress.
Hypertension
Matrix metalloproteinase-2 -735C/T polymorphism is associated with resistant hypertension in a specialized outpatient clinic in Brazil.
Hypertension
Matrix Metalloproteinase-2 Activity is Associated with Divergent Regulation of Calponin-1 in Conductance and Resistance Arteries in Hypertension-induced Early Vascular Dysfunction and Remodelling.
Hypertension
Matrix metalloproteinase-2 and -9 in glioblastoma: a trio of old drugs-captopril, disulfiram and nelfinavir-are inhibitors with potential as adjunctive treatments in glioblastoma.
Hypertension
Matrix Metalloproteinase-2 Mediates a Mechanism of Metabolic Cardioprotection Consisting of Negative Regulation of the Sterol Regulatory Element-Binding Protein-2/3-Hydroxy-3-Methylglutaryl-CoA Reductase Pathway in the Heart.
Hypertension
Matrix metalloproteinase-2, -9, and tissue inhibitor of metalloproteinase-1 in patients with hypertension.
Hypertension
Matrix metalloproteinase-9 (MMP-9), MMP-2, and serum elastase activity are associated with systolic hypertension and arterial stiffness.
Hypertension
Matrix Metalloproteinases in Vascular Disease - A Potential Therapeutic Target?
Hypertension
Matrix metalloproteinases: discrete elevations in essential hypertension and hypertensive end-stage renal disease.
Hypertension
Mechanical stretch enhances the expression and activity of osteopontin and MMP-2 via the Akt1/AP-1 pathways in VSMC.
Hypertension
Metalloproteinase inhibition ameliorates hypertension and prevents vascular dysfunction and remodeling in renovascular hypertensive rats.
Hypertension
MMP inhibition attenuates hypertensive eccentric cardiac hypertrophy and dysfunction by preserving troponin I and dystrophin.
Hypertension
MMP-2 and MMP-9 contribute to the angiogenic effect produced by hypoxia/15-HETE in pulmonary endothelial cells.
Hypertension
MMP-2 and MMP-9 levels in plasma are altered and associated with mortality in COVID-19 patients.
Hypertension
MMP-2 and sTNF-R1 Variability in Patients with Essential Hypertension: 1-Year Follow-Up Study.
Hypertension
MMP-2 mediates angiotensin II-induced hypertension under the transcriptional control of MMP-7 and TACE.
Hypertension
Morphological and biochemical characterization of remodeling in aorta and vena cava of DOCA-salt hypertensive rats.
Hypertension
Nebivolol attenuates prooxidant and profibrotic mechanisms involving TGF-? and MMPs, and decreases vascular remodeling in renovascular hypertension.
Hypertension
Nitrite treatment downregulates vascular MMP-2 activity and inhibits vascular remodeling in hypertension independently of its antihypertensive effects.
Hypertension
Polymorphisms in gene MMP-2 modify the association of cadmium exposure with hypertension risk.
Hypertension
Pyrrolidine dithiocarbamate downregulates vascular matrix metalloproteinases and ameliorates vascular dysfunction and remodeling in renovascular hypertension.
Hypertension
Reversal of deleterious effect of hypertension on the liver by inhibition of endoplasmic reticulum stress.
Hypertension
Rice bran protein hydrolysates reduce arterial stiffening, vascular remodeling and oxidative stress in rats fed a high-carbohydrate and high-fat diet.
Hypertension
Role of MMP-2 and MMP-9 in resistance to drug therapy in patients with resistant hypertension.
Hypertension
Spironolactone and hydrochlorothiazide exert antioxidant effects and reduce vascular matrix metalloproteinase-2 activity and expression in a model of renovascular hypertension.
Hypertension
Suppression of ?1-Adrenoceptor Autoantibodies is Involved in the Antiarrhythmic Effects of Omega-3 Fatty Acids in Male and Female Hypertensive Rats.
Hypertension
Synergistic effect of mitral expression of tissue inhibitor of metalloproteinase-2 with hypertension on the occurrence of mitral chordae tendinae rupture.
Hypertension
Temporal changes in cardiac matrix metalloproteinase activity, oxidative stress, and TGF-? in renovascular hypertension-induced cardiac hypertrophy.
Hypertension
Time course involvement of matrix metalloproteinases in the vascular alterations of renovascular hypertension.
Hypertension
TNF-? inhibition decreases MMP-2 activity, reactive oxygen species formation and improves hypertensive vascular hypertrophy independent of its effects on blood pressure.
Hypertension
[Metalloproteinases MMP-2 and MMP-9 and their inhibitors TIMP-1 and TIMP-2 levels in children and adolescents with type 1 diabetes.]
Hypertension
[The markers of inflammation reaction and dysfunction of endothelium in pregnant women with hypertension disorders of various genesis].
Hypertension, Portal
Neutrophil gelatinase associated lipocalin and Cystatin C in cirrhosis and portal hypertension: Relations to organ extraction and dysfunction.
Hypertension, Pregnancy-Induced
A stromal interaction molecule 1 variant up-regulates matrix metalloproteinase-2 expression by strengthening nucleoplasmic Ca(2+) signaling.
Hypertension, Pregnancy-Induced
Association between matrix metalloproteinase (MMP)-2 polymorphisms and MMP-2 levels in hypertensive disorders of pregnancy.
Hypertension, Pregnancy-Induced
Effects of Matrix Metalloproteinase (MMP)-2 Polymorphisms on Responsiveness to Antihypertensive Therapy of Women with Hypertensive Disorders of Pregnancy.
Hypertension, Pregnancy-Induced
Matrix metalloproteinase-2 C-735T and its interaction with matrix metalloproteinase-7 A-181G polymorphism are associated with the risk of preeclampsia: influence on total antioxidant capacity and blood pressure.
Hypertension, Pregnancy-Induced
Matrix metalloproteinase-2 is elevated in midtrimester amniotic fluid prior to the development of preeclampsia.
Hypertension, Pregnancy-Induced
[Expression of trophoblast invasion related genes mRNA and protein in human placenta in preeclampsia]
Hypertension, Pulmonary
Effects of angiotensin II intervention on MMP-2, MMP-9, TIMP-1, and collagen expression in rats with pulmonary hypertension.
Hypertension, Pulmonary
Effects of Dietary Copper-Methionine on Matrix Metalloproteinase-2 in the Lungs of Cold-Stressed Broilers as an Animal Model for Pulmonary Hypertension.
Hypertension, Pulmonary
Gelatinase expression in pulmonary arteries during experimental pulmonary hypertension.
Hypertension, Pulmonary
Gene expressions of nitric oxide synthase and matrix metalloproteinase-2 in monocrotaline-induced pulmonary hypertension in rats after bosentan treatment.
Hypertension, Pulmonary
hsa-miR-106b-5p participates in the development of chronic thromboembolic pulmonary hypertension via targeting matrix metalloproteinase 2.
Hypertension, Pulmonary
Immunohistochemical study of endothelin-1 and matrix metalloproteinases in plexogenic pulmonary arteriopathy.
Hypertension, Pulmonary
L-arginine attenuates acute pulmonary embolism-induced increases in lung matrix metalloproteinase-2 and matrix metalloproteinase-9.
Hypertension, Pulmonary
Protective effects of atorvastatin in rat models of acute pulmonary embolism: involvement of matrix metalloproteinase-9.
Hypertension, Renovascular
Atorvastatin and sildenafil decrease vascular TGF-? levels and MMP-2 activity and ameliorate arterial remodeling in a model of renovascular hypertension.
Hypertension, Renovascular
Comparative study on antioxidant effects and vascular matrix metalloproteinase-2 downregulation by dihydropyridines in renovascular hypertension.
Hypertension, Renovascular
Dynamics of Distribution of Capillaries with Matrix Metalloproteinase-2 and Its Tissue Inhibitor in Rat Brain during Development of Experimental Hypertension.
Hypertension, Renovascular
Quercetin decreases the activity of matrix metalloproteinase-2 and ameliorates vascular remodeling in renovascular hypertension.
Hypertension, Renovascular
Spironolactone and hydrochlorothiazide exert antioxidant effects and reduce vascular matrix metalloproteinase-2 activity and expression in a model of renovascular hypertension.
Hypertension, Renovascular
The Nuclear Factor kappaB Inhibitor Pyrrolidine Dithiocarbamate Prevents Cardiac Remodelling and Matrix Metalloproteinase-2 Up-Regulation in Renovascular Hypertension.
Hypertension, Renovascular
Verapamil decreases calpain-1 and matrix metalloproteinase-2 activities and improves hypertension-induced hypertrophic cardiac remodeling in rats.
Hypertriglyceridemia
Management of cardiac fibrosis in diabetic rats; the role of peroxisome proliferator activated receptor gamma (PPAR-gamma) and calcium channel blockers (CCBs).
Hypertrophy, Left Ventricular
Effect of phentolamine on myocardial extracellular matrix of cardiac remodeling in rats.
Hypertrophy, Left Ventricular
Effects of crocetin on the matrix metalloproteinases in cardiac hypertrophy induced by norepinephrine in rats.
Hypertrophy, Left Ventricular
Excessive activation of matrix metalloproteinases coincides with left ventricular remodeling during transition from hypertrophy to heart failure in hypertensive rats.
Hypertrophy, Left Ventricular
Matrix metalloproteinase-2 -735C/T polymorphism is associated with resistant hypertension in a specialized outpatient clinic in Brazil.
Hypertrophy, Right Ventricular
Captopril attenuates matrix metalloproteinase-2 and -9 in monocrotaline-induced right ventricular hypertrophy in rats.
Hypertrophy, Right Ventricular
Inhaled PLGA Particles of Prostaglandin E1 Ameliorate Symptoms and Progression of Pulmonary Hypertension at a Reduced Dosing Frequency.
Hypoalbuminemia
Identification of matrix metalloproteinase-2 and -9 activities within the intestinal mucosa of dogs with chronic enteropathies.
Hypotension
Small interfering RNA targeting focal adhesion kinase prevents cardiac dysfunction in endotoxemia.
Hypoxia-Ischemia, Brain
Correlation of MMP-2 gene polymorphism with neonatal hypoxic-ischemic encephalopathy.
Idiopathic Interstitial Pneumonias
Characteristic elevation of matrix metalloproteinase activity in idiopathic interstitial pneumonias.
Idiopathic Pulmonary Fibrosis
Matrix metalloproteinase-2, -7, and -9 activities in dogs with idiopathic pulmonary fibrosis compared to healthy dogs and dogs with other respiratory diseases.
IgA Vasculitis
A case of anaphylactoid purpura with multiple blister formation: possible pathophysiological role of gelatinase (MMP-9).
Ileitis
Selective gelatinase inhibition reduces apoptosis and pro-inflammatory immune cell responses in Campylobacter jejuni-infected gnotobiotic IL-10 deficient mice.
Immune System Diseases
Characterization of porcine MMP-2 and its association with immune traits.
Infarction, Middle Cerebral Artery
Activation systems for latent matrix metalloproteinase-2 are upregulated immediately after focal cerebral ischemia.
Infarction, Middle Cerebral Artery
Brain regional and cellular localization of gelatinase activity in rat that have undergone transient middle cerebral artery occlusion.
Infarction, Middle Cerebral Artery
Different expression of ubiquitin C-terminal hydrolase-L1 and ?II-spectrin in ischemic and hemorrhagic stroke: Potential biomarkers in diagnosis.
Infarction, Middle Cerebral Artery
Hyperbaric oxygen preconditioning attenuates hyperglycemia-enhanced hemorrhagic transformation by inhibiting matrix metalloproteinases in focal cerebral ischemia in rats.
Infarction, Middle Cerebral Artery
Matrix metalloproteinase-2 deletions protect against hemorrhagic transformation after 1h of cerebral ischemia and 23h of reperfusion.
Infarction, Middle Cerebral Artery
Plasma and brain matrix metalloproteinase-9 after acute focal cerebral ischemia in rats.
Infarction, Middle Cerebral Artery
Tissue inhibitor of metalloproteinases protect blood-brain barrier disruption in focal cerebral ischemia.
Infections
A role for matrix metalloproteinase-9 in pathogenesis of urogenital Chlamydia muridarum infection in mice.
Infections
A role for the 72 kDa gelatinase (MMP-2) and its inhibitor (TIMP-2) in human parturition, premature rupture of membranes and intraamniotic infection.
Infections
Ablation of matrix metalloproteinase-9 increases severity of viral myocarditis in mice.
Infections
Activation of human progelatinase A/promatrix metalloproteinase 2 by Escherichia coli-derived serine proteinase.
Infections
Activation of MMP-9 by human lung epithelial cells in response to cystic fibrosis associated pathogen Burkholderia cenocepacia reduced wound healing in vitro.
Infections
Activity of matrix metalloproteinase 2 and 9 isoforms in sputum samples from individuals infected with M. tuberculosis.
Infections
Adenoviral vectors expressing fusogenic membrane glycoproteins activated via matrix metalloproteinase cleavable linkers have significant antitumor potential in the gene therapy of gliomas.
Infections
Adenovirus-mediated small interfering RNA against matrix metalloproteinase-2 suppresses tumor growth and lung metastasis in mice.
Infections
Adrenal Steroids Modulate Fibroblast-Like Synoviocytes Response During B. abortus Infection.
Infections
Arginase 1 is expressed in myelocytes/metamyelocytes and localized in gelatinase granules of human neutrophils.
Infections
Brucella abortus Invasion of Osteocytes Modulates Connexin 43 and Integrin Expression and Induces Osteoclastogenesis via Receptor Activator of NF-?B Ligand and Tumor Necrosis Factor Alpha Secretion.
Infections
Cadherin-11 involves in synovitis and increases the migratory and invasive capacity of fibroblast-like synoviocytes of osteoarthritis.
Infections
Chlamydia pneumoniae infection induces an unstable atherosclerotic plaque phenotype in LDL-receptor, ApoE double knockout mice.
Infections
Chlamydia pneumoniae infection of microglial cells in vitro: a model of microbial infection for neurological disease.
Infections
Chlamydia trachomatis enhances the expression of matrix metalloproteinases in an in vitro model of the human fallopian tube infection.
Infections
Circulating levels of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases during Japanese encephalitis virus infection.
Infections
Clinical Correlation with the PA/Plasmin System in Septic Arthritis of the Knee.
Infections
Clove Bud Oil Modulates Pathogenicity Phenotypes of the Opportunistic Human Pathogen Pseudomonas aeruginosa.
Infections
Collagenolytic enzymes (gelatinases) and their inhibitors in human amniochorionic membrane.
Infections
Colonic Expression of Genes Encoding Inflammatory Mediators and Gelatinases During Campylobacter Jejuni Infection of Conventional Infant Mice.
Infections
Comparative study for the presence of enterococcal virulence factors gelatinase, hemolysin and biofilm among clinical and commensal isolates of enterococcus faecalis.
Infections
Correlation between matrix metalloproteinase expression and activation of the focal adhesion kinase signaling pathway in herpes stromal keratitis.
Infections
Cryptococcus neoformans pulmonary granuloma formation is associated with matrix metalloproteinase-2 expression.
Infections
Cytomegalovirus-caused release of collagenase IV from human cerebral microvascular endothelial cells.
Infections
Design, synthesis and anti-HIV-1 evaluation of hydrazide-based peptidomimetics as selective gelatinase inhibitors.
Infections
Detection of Enterococcus faecalis in subgingival biofilms of healthy, gingivitis, and chronic periodontitis subjects.
Infections
Diagnostic accuracy of urine neutrophil gelatinase-associated lipocalin and urine kidney injury molecule-1 as predictors of acute pyelonephritis in young children with febrile urinary tract infection.
Infections
Didanosine (ddI) associates with increased liver fibrosis in adult HIV-HCV coinfected patients.
Infections
Difference in Host Immune response to Methicillin-Resistant and Methicillin Sensitive Staphylococcus aureus (MRSA and MSSA) Endophthalmitis.
Infections
Different responses in MMPs/TIMPs expression of U937 and HepG2 cells to dengue virus infection.
Infections
Differential expression of hepatic fibrosis mediators in sick and spontaneously recovered mice with experimental biliary atresia.
Infections
Differential secretion of matrix metalloproteinase-2 and -9 after selective infection with group B streptococci in human fetal membranes.
Infections
Discoidin domain receptor 2 regulates fibroblast proliferation and migration through the extracellular matrix in association with transcriptional activation of matrix metalloproteinase-2.
Infections
Dual neutralization of TNFR-2 and MMP-2 regulates the severity of S. aureus induced septic arthritis correlating alteration in the level of interferon gamma and interleukin-10 in terms of TNFR2 blocking.
Infections
Early prediction of urinary tract infection with urinary neutrophil gelatinase associated lipocalin.
Infections
Effect of adenovirus-mediated overexpression of decorin on metalloproteinases, tissue inhibitors of metalloproteinases and cytokines secretion by human gingival fibroblasts.
Infections
Effect of respiratory syncytial virus on the activity of matrix metalloproteinase in mice.
Infections
Efficiency of controlled topical delivery of silver sulfadiazine in infected burn wounds.
Infections
Efficient infection of mature skeletal muscle with herpes simplex virus vectors by using dextran sulfate as a co-receptor.
Infections
Enzymatic activity of Microsporum canis and Trichophyton mentagrophytes from breeding rabbits with and without skin lesions.
Infections
Enzymatically active Peptostreptococcus magnus: association with site of infection.
Infections
Eradication of Helicobacter pylori infection favourably affects altered gastric mucosal MMP-9 levels.
Infections
Evidence of in vivo differential bioavailability of the active forms of matrix metalloproteinases 9 and 2 in parturition, spontaneous rupture of membranes, and intra-amniotic infection.
Infections
Expression of matrix metalloproteinases subsequent to urogenital Chlamydia muridarum infection of mice.
Infections
Functional characterization of a matrix metalloproteinase 2 gene in Litopenaeus vannamei.
Infections
GM-CSF- and TNF-{alpha}-mediated matrix metalloproteinase production by human osteoblasts and monocytes upon infection with Brucella abortus.
Infections
Hepatitis C virus activates Bcl-2 and MMP-2 expression through multiple cellular signaling pathways.
Infections
High expression of protein phosphatase 4 is associated with the aggressive malignant behavior of colorectal carcinoma.
Infections
High fat diet modulates inflammatory parameters in the heart and liver during acute Trypanosoma cruzi infection.
Infections
HIV-1 interaction with human mannose receptor (hMR) induces production of matrix metalloproteinase 2 (MMP-2) through hMR-mediated intracellular signaling in astrocytes.
Infections
Human neural stem cell-derived neuron/astrocyte co-cultures respond to La Crosse virus infection with proinflammatory cytokines and chemokines.
Infections
Identification of matrix metalloproteinase-9 in amniotic fluid and amniochorion in spontaneous labor and after experimental intrauterine infection or interleukin-1 beta infusion in pregnant rhesus monkeys.
Infections
Imbalance of pro- and antifibrogenic genes and bile duct injury in murine Schistosoma mansoni infection-induced liver fibrosis.
Infections
Immunohistochemical analysis of MMP-9, MMP-2 and TIMP-1, TIMP-2 expression in the central nervous system following infection with viral and bacterial meningitis.
Infections
In vivo assessment of growth and virulence gene expression during commensal and pathogenic lifestyles of luxABCDE-tagged Enterococcus faecalis strains in murine gastrointestinal and intravenous infection models.
Infections
Incidence of hemolysin, gelatinase, and aggregation substance among enterococci isolated from patients with endocarditis and other infections and from feces of hospitalized and community-based persons.
Infections
Increased activities of cardiac matrix metalloproteinases matrix metalloproteinase (MMP)-2 and MMP-9 are associated with mortality during the acute phase of experimental Trypanosoma cruzi infection.
Infections
Increased expression of matrix metalloproteinase-2 and 9 and human papilloma virus infection are associated with malignant transformation of sinonasal inverted papilloma.
Infections
Increased intrahepatic cyclooxygenase 2, matrix metalloproteinase 2, and matrix metalloproteinase 9 expression is associated with progressive liver disease in chronic hepatitis C virus infection: role of viral core and NS5A proteins.
Infections
Increased production of matrix metalloproteinases 1 and 3 by smooth muscle cells upon infection with Chlamydia pneumoniae.
Infections
Increased production of matrix metalloproteinases in Helicobacter pylori-associated human gastritis.
Infections
Increased urinary neutrophil gelatinase associated lipocalin in urinary tract infections and leukocyturia.
Infections
Increased urinary neutrophil gelatinase associated lipocalin levels in a rat model of upper urinary tract infection.
Infections
Induction of matrix metalloproteinases (MMPs) and tissue inhibitors of MMPs correlates with outcome of acute experimental pseudomonal keratitis.
Infections
Influence of persistent canine distemper virus infection on expression of RECK, matrix-metalloproteinases and their inhibitors in a canine macrophage/monocytic tumour cell line (DH82).
Infections
Integration of transcriptomic profile of SARS-CoV-2 infected normal human bronchial epithelial cells with metabolic and protein-protein interaction networks.
Infections
Involvement of matrix metalloproteinases and their inhibitors in Staphylococcus aureus chronically infected bovine mammary glands during active involution.
Infections
Kaposi's sarcoma-associated herpesvirus infection promotes invasion of primary human umbilical vein endothelial cells by inducing matrix metalloproteinases.
Infections
Lentivirus infection in the brain induces matrix metalloproteinase expression: role of envelope diversity.
Infections
Levels of Matrix Metalloproteinase-2 and -9 in the Cerebrospinal Fluid of Dogs with Visceral Leishmaniasis.
Infections
Levels of plasma matrix metalloproteinases (MMP-2 and MMP-9) in response to INTEGRA® dermal regeneration template implantation.
Infections
Levocetirizine inhibits rhinovirus-induced up-regulation of fibrogenic and angiogenic factors in nasal polyp fibroblasts.
Infections
Lymphoid tissue collagen deposition in HIV-infected patients correlates with the imbalance between matrix metalloproteinases and their inhibitors.
Infections
Matrix metalloproteinase 2 of grass carp Ctenopharyngodon idella (CiMMP2) is involved in the immune response against bacterial infection.
Infections
Matrix metalloproteinase-2 contributes to joint destruction in group B streptococcus-induced arthritis.
Infections
Matrix Metalloproteinase-2 Mediates Intestinal Immunopathogenesis in Campylobacter Jejuni-Infected Infant Mice.
Infections
Matrix metalloproteinase-9 amplifies the immune response to Pseudomonas aeruginosa corneal infection.
Infections
Matrix metalloproteinases and their tissue inhibitors in serum and cerebrospinal fluid of children with Japanese encephalitis virus infection.
Infections
Matrix metalloproteinases and tissue inhibitors of metalloproteinases in coxsackievirus-induced myocarditis.
Infections
Matrix metalloproteinases in the cervical mucus plug in relation to gestational age, plug compartment, and preterm labor.
Infections
Matrix Metalloproteinases Vary with Airway Microbiota Composition and Lung Function in Non-Cystic Fibrosis Bronchiectasis.
Infections
Matrix metaloproteinase-2 and placentary dysfunction development in pregnancy with perinatal infections
Infections
Metalloproteinases 2 and 9 Immunoexpression in Periapical Lesions from Primary Endodontic Infection: Possible Relationship with the Histopathological Diagnosis and the Presence of Pain.
Infections
Modified Profile of Matrix Metalloproteinase 2 and 9 Production by Human Fallopian Tube Epithelial Cells After Infection In Vitro With Neisseria gonorrhoeae.
Infections
Molecular epidemiology of the fsr locus and of gelatinase production among different subsets of Enterococcus faecalis isolates.
Infections
Mycobacterium tuberculosis-infected human monocytes down-regulate microglial MMP-2 secretion in CNS tuberculosis via TNF?, NF?B, p38 and caspase 8 dependent pathways.
Infections
Neutralization of MMP-2 and TNFR1 Regulates the Severity of S. aureus-Induced Septic Arthritis by Differential Alteration of Local and Systemic Proinflammatory Cytokines in Mice.
Infections
Neutralization of MMP-2 protects Staphylococcus aureus infection induced septic arthritis in mice and regulates the levels of cytokines.
Infections
Peculiarities of changes in indices of calcium and zinc trace elements and matrix metalloproteinase-2 in pregnant women with perinatal infections.
Infections
Potential Role of Fibroblast-Like Synoviocytes in Joint Damage Induced by Brucella abortus Infection through Production and Induction of Matrix Metalloproteinases.
Infections
Proteolytic activation of corneal matrix metalloproteinase by Pseudomonas aeruginosa elastase.
Infections
Relationship between metalloproteinase-2 and -9 levels in plasma and vaginal secretion with preterm birth.
Infections
Relationship between MMP Expression and Virulence of Dengue Virus Type-2 in Infected Mosquito and Mammalian Cells.
Infections
Relative expression of matrix metalloproteinase-2 and -9 in synovial fluid from healthy calves and calves with experimentally induced septic arthritis.
Infections
Rhinovirus upregulates matrix metalloproteinase-2, matrix metalloproteinase-9, and vascular endothelial growth factor expression in nasal polyp fibroblasts.
Infections
Sendai virus infection up-regulates trypsin I and matrix metalloproteinase-9, triggering viral multiplication and matrix degradation in rat lungs and lung L2 cells.
Infections
Serological cytokine profiles of cardiac rejection and lung infection after heart transplantation in rats.
Infections
Serum levels of matrix metalloproteinase-2, -9, and vitamin D in patients with multiple sclerosis with or without herpesvirus-6 seropositivity.
Infections
Sialic acid removal by trans-sialidase modulates MMP-2 activity during Trypanosoma cruzi infection.
Infections
Staphylococcus aureus Biofilm Infection Compromises Wound Healing by Causing Deficiencies in Granulation Tissue Collagen.
Infections
Staphylococcus aureus increases cytokine and matrix metalloproteinase expression in nasal mucosae of patients with chronic rhinosinusitis and nasal polyps.
Infections
Strong biofilm production, antibiotic multi-resistance and high gelE expression in epidemic clones of Enterococcus faecalis from orthopaedic implant infections.
Infections
Study of biological characteristics of Pseudomonas aeruginosa strains isolated from patients with cystic fibrosis and from patients with extra-pulmonary infections.
Infections
Synergic and antagonistic relationship between MMP-2 and MMP-9 with fibrosis and inflammation in Chagas' cardiomyopathy.
Infections
The effect of Candida albicans systemic infection on matrix metalloproteinases in breast cancer bearing BALB/c mice.
Infections
The Intraperitoneal Transcriptome of the Opportunistic Pathogen Enterococcus faecalis in Mice.
Infections
The role of metalloproteases in Leishmania species infection in the New World: a systematic review.
Infections
The use of pentoxifylline as adjuvant therapy with praziquantel downregulates profibrogenic cytokines, collagen deposition and oxidative stress in experimental schistosomiasis mansoni.
Infections
Therapeutical effects of vaccine from Trypanosoma cruzi amastigote surface protein 2 by simultaneous inoculation with live parasites.
Infections
Tissue inhibitor of metalloproteinase-3 expression from an oncolytic adenovirus inhibits matrix metalloproteinase activity in vivo without affecting antitumor efficacy in malignant glioma.
Infections
Treponema denticola upregulates MMP-2 activation in periodontal ligament cells: interplay between epigenetics and periodontal infection.
Infections
Upregulation of extracellular matrix metalloproteinase inducer (EMMPRIN) and gelatinases in human atherosclerosis infected with Chlamydia pneumoniae: the potential role of Chlamydia pneumoniae infection in the progression of atherosclerosis.
Infections
Ureaplasma Urealyticum Infection Contributes to the Development of Pelvic Endometriosis Through Toll-Like Receptor 2.
Infections
Urinary Neutrophil Gelatinase Associated Lipocalin - A Sensitive Marker for Urinary Tract Infection in Children.
Infections
Zymographic analysis of latent and activated forms of matrix metalloproteinase-2 and -9 in synovial fluid: correlation to polymorphonuclear leukocyte infiltration and in response to infection.
Infections
[Effect of cytomegalovirus infection on expression of matrix metalloproteinase-2 in human endothelial cells.]
Infections
[Helicobacter pylori infection, the invasion and metastasis of the gastric carcinoma, and the expression of MMP-2 and TIMP-2]
Infections
[Therapeutic effect of Haobieyangyinruanjianfang on the mouse liver fibrosis caused by schistosomiasis]
Infections
[Virulence genes and bacteriocins in Enterococcus faecalis strains isolated from different clinical samples in Maule Region, Chile].
Inferior Wall Myocardial Infarction
Plasma MMP-9 and MMP-2 following acute myocardial infarction in man: correlation with echocardiographic and neurohumoral parameters of left ventricular dysfunction.
Infertility
Altered expression of genes involved in the production and degradation of endometrial extracellular matrix in patients with unexplained infertility and recurrent miscarriages.
Infertility
Endometrial mRNA expression of matrix metalloproteinases, their tissue inhibitors and cell adhesion molecules in unexplained infertility and implantation failure patients.
Infertility
Matrix metalloproteinase 2 is associated with changes in steroid hormones in the sera and peritoneal fluid of patients with endometriosis.
Infertility, Male
MMP2, MMP9 and TIMP2 polymorphisms affect sperm parameters but not fertility in Polish males.
Inflammatory Bowel Diseases
Enhanced expression of MMP-7 and MMP-13 in inflammatory bowel disease: a precancerous potential?
Inflammatory Bowel Diseases
Expression of matrix metalloproteinases-2 and -9 in intestinal tissue of patients with inflammatory bowel diseases.
Inflammatory Bowel Diseases
Fecal Neutrophil Gelatinase Associated Lipocalin (NGAL) as a biomarker for Inflammatory Bowel Disease.
Inflammatory Bowel Diseases
Gelatinase A (MMP-2), collagenase-2 (MMP-8), and laminin-5 gamma2-chain expression in murine inflammatory bowel disease (ulcerative colitis).
Inflammatory Bowel Diseases
Identification of Matrix Metalloproteinase-2 and -9 Activities within Intestinal Mucosa of Clinically Healthy Beagle Dogs.
Inflammatory Bowel Diseases
Identification of matrix metalloproteinase-2 and -9 activities within the intestinal mucosa of dogs with chronic enteropathies.
Inflammatory Bowel Diseases
Inhibition of gelatinase B/MMP-9 does not attenuate colitis in murine models of inflammatory bowel disease.
Inflammatory Bowel Diseases
Role of MMP-2 and MMP-9 and their natural inhibitors in liver fibrosis, chronic pancreatitis and non-specific inflammatory bowel diseases.
Inflammatory Bowel Diseases
Selective ablation of matrix metalloproteinase-2 exacerbates experimental colitis: contrasting role of gelatinases in the pathogenesis of colitis.
Inflammatory Bowel Diseases
Targeted deletion of metalloproteinase 9 attenuates experimental colitis in mice: central role of epithelial-derived MMP.
Inflammatory Bowel Diseases
Ulcer-associated cell lineage expresses genes involved in regeneration and is hallmarked by high neutrophil gelatinase-associated lipocalin (NGAL) levels.
Inflammatory Bowel Diseases
Unlocking the Gates to Inflammatory Bowel Disease: The Role of Enterococcus faecalis Gelatinase.
Inflammatory Breast Neoplasms
Membrane type-1 matrix metalloproteinase (MT1-MMP) correlates with the expression and activation of matrix metalloproteinase-2 (MMP-2) in inflammatory breast cancer.
Influenza, Human
Cigarette smoke worsens lung inflammation and impairs resolution of influenza infection in mice.
Influenza, Human
Influenza A virus infection modulates the expression of type IV collagenase in epithelial cells.
Influenza, Human
Role of matrix metalloproteinases and their inhibitor in the development of early pulmonary fibrosis in mice infected with influenza A/H5N1 A/goose/Krasnoozerskoye/627/05 virus.
Insulin Resistance
Cortisol/cortisone ratio and matrix metalloproteinase-9 activity are associated with pediatric primary hypertension.
Insulin Resistance
Defining the Regulated Secreted Proteome of Rodent Adipocytes upon the Induction of Insulin Resistance.
Insulin Resistance
Do different bariatric surgical procedures influence plasma levels of matrix metalloproteinase-2, -7, and -9 among patients with type 2 diabetes mellitus?
Insulin Resistance
Evaluation of the Effect Derived from Silybin with Vitamin D and Vitamin E Administration on Clinical, Metabolic, Endothelial Dysfunction, Oxidative Stress Parameters, and Serological Worsening Markers in Nonalcoholic Fatty Liver Disease Patients.
Insulin Resistance
Exercise ameliorates serum MMP-9 and TIMP-2 levels in patients with type 2 diabetes.
Insulin Resistance
Lipocalin-2 inhibits autophagy and induces insulin resistance in H9c2 cells.
Insulin Resistance
Resistance training and caloric restriction prevent systolic blood pressure rise by improving the nitric oxide effect on smooth muscle and morphological changes in the aorta of ovariectomized rats.
Insulin Resistance
Rice bran protein hydrolysates reduce arterial stiffening, vascular remodeling and oxidative stress in rats fed a high-carbohydrate and high-fat diet.
Insulin Resistance
Serum levels of matrix metalloproteinases MMP-2 and MMP-9 and their inhibitors in women with glucose intolerance in pregnancy and normal controls.
Insulin Resistance
Sexually Dimorphic Diet-Induced Insulin Resistance in Obese Tissue Inhibitor of Metalloproteinase-2 (TIMP-2)-Deficient Mice.
Insulin Resistance
The skin remodeling in type 1 diabetes and insulin resistance animal models.
Intervertebral Disc Degeneration
Alterations in biochemical components of extracellular matrix in intervertebral disc herniation: role of MMP-2 and TIMP-2 in type II collagen loss.
Intervertebral Disc Degeneration
Analysis of genetic polymorphisms associated with intervertebral disc degeneration.
Intervertebral Disc Degeneration
Association of the polymorphism of MMP2 with the risk and severity of lumbar disc degeneration in the Chinese Han population.
Intervertebral Disc Degeneration
Circular RNA derived from TIMP2 functions as a competitive endogenous RNA and regulates intervertebral disc degeneration by targeting miR?185?5p and matrix metalloproteinase 2.
Intervertebral Disc Degeneration
Degenerative Cervical Myelopathy: Epidemiology, Genetics, and Pathogenesis.
Intervertebral Disc Degeneration
Increased MMP-2 activity during intervertebral disc degeneration is correlated to MMP-14 levels.
Intervertebral Disc Degeneration
Induction of matrix metalloproteinase-2 and -3 activity in ovine nucleus pulposus cells grown in three-dimensional agarose gel culture by interleukin-1beta: a potential pathway of disc degeneration.
Intervertebral Disc Degeneration
MMP-2 mediates local degradation and remodeling of collagen by annulus fibrosus cells of the intervertebral disc.
Intervertebral Disc Degeneration
[Effect of Acupotomy Lysis at Cervical Acupoints on Expression of Matrix Metalloproteinases and Tissue Inhibitor of Metalloproteinase 1 and Changes of Pulpiform Nucleus Ultrastructure in Rats with Degenerated Cervical Intervertebral Discs].
Intervertebral Disc Degeneration
[Expression of hypoxia-inducible factor-1alpha and matrix metalloproteinase-2 in degenerative lumbar intervertebral disc]
Intervertebral Disc Displacement
Alterations in biochemical components of extracellular matrix in intervertebral disc herniation: role of MMP-2 and TIMP-2 in type II collagen loss.
Intervertebral Disc Displacement
Altered expression of metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in cervical disc herniation patients.
Intervertebral Disc Displacement
Analysis of genetic polymorphisms associated with intervertebral disc degeneration.
Intervertebral Disc Displacement
Expression of Matrix Metalloproteinases is Positively Related to the Severity of Disc Degeneration and Growing Age in the East Asian Lumbar Disc Herniation Patients.
Intervertebral Disc Displacement
The impact of changes in serum levels of metalloproteinase-2 and metalloproteinase-9 on pain perception in patients with disc herniation before and after surgery.
Intervertebral Disc Displacement
The increased expression of matrix metalloproteinases associated with elastin degradation and fibrosis of the ligamentum flavum in patients with lumbar spinal stenosis.
Intracranial Aneurysm
Association of functional MMP-2 gene variant with intracranial aneurysms: case-control genetic association study and meta-analysis.
Intracranial Aneurysm
Correlation between MMP-2 and NF-? B expression of intracranial aneurysm.
Intracranial Aneurysm
Effect of dietary ? carotene on cerebral aneurysm and subarachnoid haemorrhage in the brain apo E(-/-) mice.
Intracranial Aneurysm
Identification of a serum gelatinase associated with the occurrence of cerebral aneurysms as pro-matrix metalloproteinase-2.
Intracranial Aneurysm
Macrophage-derived matrix metalloproteinase-2 and -9 promote the progression of cerebral aneurysms in rats.
Intracranial Aneurysm
Matrix metalloproteinases 2 and 9 in human atherosclerotic and non-atherosclerotic cerebral aneurysms.
Intracranial Aneurysm
Matrix metalloproteinases and tissue inhibitors of metalloproteinases expression in human cerebral ruptured and unruptured aneurysm.
Intracranial Aneurysm
miR-34a regulates phenotypic modulation of vascular smooth muscle cells in intracranial aneurysm by targeting CXCR3 and MMP-2.
Intracranial Aneurysm
The effect of intravascular interventional embolization and craniotomy on MMP-2, MMP-9 and caspase3 in serum of intracranial aneurysm patients.
Intracranial Aneurysm
The role of MMP-2 and MMP-9 polymorphisms in sporadic intracranial aneurysms.
Intracranial Arteriosclerosis
Biomarkers and location of atherosclerosis: Matrix metalloproteinase-2 may be related to intracranial atherosclerosis.
Intracranial Hemorrhages
Association between expression of MMP-2 and MMP-9 genes and pathogenesis of intracranial hemorrhage in severe coagulation factor XIII deficiency.
Intracranial Hemorrhages
Clinical efficacy of mouse nerve growth factor plus nimodipine in neonatal intracranial hemorrhage and its effect on plasma PAF, CNP, MMP-2, and neurological function.
Intracranial Hemorrhages
Expression and CpG island methylation pattern of MMP-2 and MMP-9 genes in patients with congenital factor XIII deficiency and intracranial hemorrhage.
Intracranial Hemorrhages
[Study on expression of matrix metalloproteinase-2 and matrix metalloproteinase-9 in brain tissue adjacent to hemorrhage after brain hemorrhage in human]
Ischemic Attack, Transient
Effect of Propofol Post-treatment on Blood-Brain Barrier Integrity and Cerebral Edema After Transient Cerebral Ischemia in Rats.
Ischemic Stroke
A gelatin in situ-overlay technique localizes brain matrix metalloproteinase activity in experimental focal cerebral ischemia.
Ischemic Stroke
Association between microRNA binding site polymorphisms in immunoinflammatory genes and recurrence risk of ischemic stroke.
Ischemic Stroke
Cerebral mast cells mediate blood-brain barrier disruption in acute experimental ischemic stroke through perivascular gelatinase activation.
Ischemic Stroke
Complexity in differentiating truncated or matured forms of MMP-2 and MMP-9 by zymography in acute ischemic stroke induced rat brain tissues.
Ischemic Stroke
Correlation between matrix metalloproteinase-2 polymorphisms and first and recurrent atherosclerotic ischemic stroke events: a case-control study.
Ischemic Stroke
Decreased plasma decorin levels following acute ischemic stroke: correlation with MMP-2 and differential expression in TOAST subtypes.
Ischemic Stroke
Different expression of ubiquitin C-terminal hydrolase-L1 and ?II-spectrin in ischemic and hemorrhagic stroke: Potential biomarkers in diagnosis.
Ischemic Stroke
Different roles of matrix metalloproteinases-2 and -9 after human ischaemic stroke.
Ischemic Stroke
Discovery of 7-aminophenanthridin-6-one as a new scaffold for matrix metalloproteinase inhibitors with multitarget neuroprotective activity.
Ischemic Stroke
Do extracellular-matrix-regulating enzymes play a role in cervical artery dissection?
Ischemic Stroke
Early upregulation of matrix metalloproteinases following reperfusion triggers neuroinflammatory mediators in brain ischemia in rat.
Ischemic Stroke
Effect of neutrophil depletion on gelatinase expression, edema formation and hemorrhagic transformation after focal ischemic stroke.
Ischemic Stroke
Effects of Mesenchymal Stem Cell Treatment on the Expression of Matrix Metalloproteinases and Angiogenesis during Ischemic Stroke Recovery.
Ischemic Stroke
Influence of interleukin-1 beta gene polymorphisms on the risk of myocardial infarction and ischemic stroke at young age in vivo and in vitro.
Ischemic Stroke
Intranuclear matrix metalloproteinases promote DNA damage and apoptosis induced by oxygen-glucose deprivation in neurons.
Ischemic Stroke
Intraplaque MMP-8 levels are increased in asymptomatic patients with carotid plaque progression on ultrasound.
Ischemic Stroke
Matrix metalloproteinase-2 gene polymorphisms are associated with ischemic stroke in a Hainan population.
Ischemic Stroke
Methylation in the matrix metalloproteinase-2 gene is associated with cerebral ischemic stroke.
Ischemic Stroke
Oxidative Stress Biomarkers of Brain Damage: Hyperacute Plasma F2-Isoprostane Predicts Infarct Growth in Stroke.
Ischemic Stroke
Profiles of matrix metalloproteinases, their inhibitors, and laminin in stroke patients: influence of different therapies.
Ischemic Stroke
White Matter Hyperintensity Volume Correlates with Matrix Metalloproteinase-2 in Acute Ischemic Stroke.
Jaw Cysts
Identification and characterization of gelatinases/type IV collagenases in jaw cysts.
Joint Diseases
A crucial role for matrix metalloproteinase 2 in osteocytic canalicular formation and bone metabolism.
Joint Diseases
A novel mutation in the matrix metallopeptidase 2 coding gene associated with intrafamilial variability of multicentric osteolysis, nodulosis, and arthropathy.
Joint Diseases
Al-Aqeel Sewairi syndrome, a new autosomal recessive disorder with multicentric osteolysis, nodulosis and arthropathy. The first genetic defect of matrix metalloproteinase 2 gene.
Joint Diseases
Bisphosphonates in multicentric osteolysis, nodulosis and arthropathy (MONA) spectrum disorder - an alternative therapeutic approach.
Joint Diseases
Characterisation of the cell type-specificity of collagenase 3 mRNA expression in comparison with membrane type 1 matrix metalloproteinase and gelatinase A in the synovial membrane in rheumatoid arthritis.
Joint Diseases
Comparative Serum Analyses Identify Cytokines and Hormones Commonly Dysregulated as Well as Implicated in Promoting Osteolysis in MMP-2-Deficient Mice and Children.
Joint Diseases
Determination of MMP-2 and -9 activities in synovial fluid of horses with osteoarthritic and arthritic joint diseases using gelatin zymography and immunocapture activity assays.
Joint Diseases
Loss of MMP-2 in osteoblasts upregulates osteopontin and bone sialoprotein expression in a circuit regulating bone homeostasis.
Joint Diseases
Matrix metalloproteinase, vitamin A and methylprednisolone effects on experimentally induced amyloid arthropathy.
Joint Diseases
Measurement of cartilage oligomeric matrix protein (COMP) in normal and diseased equine synovial fluids.
Joint Diseases
Multicentric osteolysis with nodulosis and arthropathy (MONA) with cardiac malformation, mimicking polyarticular juvenile idiopathic arthritis: case report and literature review.
Joint Diseases
Multicentric Osteolysis, Nodulosis, and Arthropathy in two unrelated children with matrix metalloproteinase 2 variants: Genetic-skeletal correlations.
Joint Diseases
Synovial fluid gelatinase concentrations and matrix metalloproteinase and cytokine expression in naturally occurring joint disease in horses.
Joint Diseases
The role of matrix metalloproteinase-2 and matrix metalloproteinase-9 in antibody-induced arthritis.
Keloid
Efficacy and possible mechanisms of Botulinum Toxin type A on hypertrophic scarring.
Keloid
High-mobility Group Box Protein-1, Matrix Metalloproteinases, and Vitamin D in Keloids and Hypertrophic Scars.
Keloid
Keloid-derived fibroblasts show increased secretion of factors involved in collagen turnover and depend on matrix metalloproteinase for migration.
Keloid
Matrix metalloproteinase-2 and -9 activities in human keloids, hypertrophic and atrophic scars: a pilot study.
Keloid
Promoted activation of matrix metalloproteinase (MMP)-2 in keloid fibroblasts and increased expression of MMP-2 in collagen bundle regions: implications for mechanisms of keloid progression.
Keloid
TGF-beta1 antisense therapy modulates expression of matrix metalloproteinases in keloid-derived fibroblasts.
Keloid
Tissue Inhibitor of Metalloproteinase-2 Suppresses Collagen Synthesis in Cultured Keloid Fibroblasts.
Keratitis
Correlation between matrix metalloproteinase expression and activation of the focal adhesion kinase signaling pathway in herpes stromal keratitis.
Keratitis
Detection of virulence factors in Serratia strains isolated from contact lens-associated corneal ulcers.
Keratitis
Evaluation of matrix metalloproteinase concentrations in precorneal tear film from dogs with Pseudomonas aeruginosa-associated keratitis.
Keratitis
Immunohistochemical study of matrix metalloproteinases-2 and -9, macrophage inflammatory protein-2 and tissue inhibitors of matrix metalloproteinases-1 and -2 in normal, purulonecrotic and fungal infected equine corneas.
Keratitis
JAK/STAT regulation of Aspergillus fumigatus corneal infections and IL-6/23-stimulated neutrophil, IL-17, elastase, and MMP9 activity.
Keratitis
Modulation of Corneal FAK/PI3K/Akt Signaling Expression and of Metalloproteinase-2 and Metalloproteinase-9 during the Development of Herpes Simplex Keratitis.
Keratitis
Testican-1 Promotes Resistance against Pseudomonas aeruginosa-Induced Keratitis through Regulation of MMP-2 Expression and Activation.
Keratitis, Herpetic
Active form of gelatinases in tear fluidin patients with corneal ulcer or ocular burn.
Keratitis, Herpetic
Modulation of Corneal FAK/PI3K/Akt Signaling Expression and of Metalloproteinase-2 and Metalloproteinase-9 during the Development of Herpes Simplex Keratitis.
Keratoacanthoma
Immunolocalizations of human gelatinase (type IV collagenase, MMP-9) and TIMP (tissue inhibitor of metalloproteinases) in normal epidermis and some epidermal tumors.
Keratoacanthoma
Transformation-specific matrix metalloproteinases, MMP-7 and MMP-13, are present in epithelial cells of keratoacanthomas.
Keratoconjunctivitis
Metalloproteinases in canine experimental traumatic keratoconjunctivitis.
Keratoconus
Altered gelatinolytic activities in an apparent unilateral keratoconus patient. A case report.
Keratoconus
Elements of the nitric oxide pathway can degrade TIMP-1 and increase gelatinase activity.
Keratoconus
Expression of membrane-type 1 matrix metalloproteinase (MT1-MMP) and MMP-2 in normal and keratoconus corneas.
Keratoconus
Increased gelatinolytic activity in keratoconus keratocyte cultures. A correlation to an altered matrix metalloproteinase-2/tissue inhibitor of metalloproteinase ratio.
Keratoconus
The expression of human corneal MMP-2, MMP-9, proMMP-13 and TIMP-1 in bullous keratopathy and keratoconus.
Keratosis, Actinic
Epithelial expression of extracellular matrix metalloproteinase inducer/CD147 and matrix metalloproteinase-2 in neoplasms and precursor lesions derived from cutaneous squamous cells: An immunohistochemical study.
Keratosis, Actinic
Expression of Gelatinases (MMP-2, MMP-9) and Gelatinase Activator (MMP-14) in Actinic Keratosis and in In Situ and Invasive Squamous Cell Carcinoma.
Keratosis, Actinic
Expression of matrix metalloproteinase-1, -2 and -3 in squamous cell carcinoma and actinic keratosis.
Keratosis, Actinic
Metalloproteinase-2 expression correlates with aggressiveness of cutaneous squamous cell carcinomas.
Keratosis, Actinic
Protein Expression of MMP-2 and MT1-MMP in Actinic Keratosis, Squamous Cell Carcinoma of the Skin, and Basal Cell Carcinoma.
Kidney Diseases
Exploration of association of 1,25-OH2D3 with augmentation index, a composite measure of arterial stiffness.
Kidney Diseases
In Diabetic Kidney Disease Urinary Exosomes Better Represent Kidney Specific Protein Alterations Than Whole Urine.
Kidney Diseases
Intraoperative venous congestion and acute kidney injury in cardiac surgery: an observational cohort study.
Kidney Diseases
Progression of kidney disease in non-diabetic patients with coronary artery disease: predictive role of circulating matrix metalloproteinase-2, -3, and -9.
Kidney Diseases, Cystic
Matrix metalloproteinase-2 in a murine model of infantile-type polycystic kidney disease.
Kidney Failure, Chronic
Association of Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9 With Endothelial Dysfunction, Cardiovascular Disease Risk Factors and thrombotic events in Children With End-stage Renal Disease.
Kidney Failure, Chronic
Effluent Tenascin-C Levels Reflect Peritoneal Deterioration in Peritoneal Dialysis: MAJOR IN PD Study.
Kidney Failure, Chronic
Investigation of the Relationship Between IL-18 (-?607 C/A), IL-18 (-?137 G/C), and MMP-2 (-?1306 C/T) Gene Variations and Serum Copper and Zinc Levels in Patients Diagnosed with Chronic Renal Failure.
Kidney Failure, Chronic
Matrix Metalloproteinase (MMP)-2 Genetic Variants Modify the Circulating MMP-2 Levels in End-Stage Kidney Disease.
Kidney Failure, Chronic
Regulation of miR-29b and miR-30c by vitamin D receptor activators contributes to attenuate uraemia-induced cardiac fibrosis.
Kidney Failure, Chronic
Serum matrix metalloproteinases MMP-2 and MMP-9 and metalloproteinase tissue inhibitors TIMP-1 and TIMP-2 in diabetic nephropathy.
Kidney Failure, Chronic
Urinary neutrophil gelatinase associated lipocalin as a biomarker in ifosfamide induced chronic renal failure.
Kidney Neoplasms
Anticancer effect of lysine, proline, arginine, ascorbic acid and green tea extract on human renal adenocarcinoma line 786-0.
Kidney Neoplasms
Antitumor activity of irradiated riboflavin on human renal carcinoma cell line 786-O.
Kidney Neoplasms
Influence of cytokines and growth factors on matrix metalloproteinase-2 production and invasion of human renal cancer.
Kidney Neoplasms
Influence of osteopontin short hairpin RNA on the proliferation and invasion of human renal cancer cells.
Kidney Neoplasms
Progelatinase A mRNA expression in cell lines derived from tumors in patients with metastatic renal cell carcinoma correlates inversely with survival.
Kidney Neoplasms
RNA interference suppression of A100A4 reduces the growth and metastatic phenotype of human renal cancer cells via NF-kB-dependent MMP-2 and bcl-2 pathway.
Kidney Neoplasms
[mRNA expression analysis of metastatic markers in clear-cell renal cell carcinoma]
Klatskin Tumor
The expression of matrix metalloproteinases in intrahepatic cholangiocarcinoma, hilar (Klatskin tumor), middle and distal extrahepatic cholangiocarcinoma, gallbladder cancer, and ampullary carcinoma: role of matrix metalloproteinases in tumor progression and prognosis.
Klatskin Tumor
The ratio of MMP-2 to TIMP-2 in hilar cholangiocarcinoma: a semi-quantitative study.
Krukenberg Tumor
Expression and correlation of CD44v6, vascular endothelial growth factor, matrix metalloproteinase-2, and matrix metalloproteinase-9 in Krukenberg tumor.
Labyrinth Diseases
Expression of the recessive glomerulosclerosis gene Mpv17 regulates MMP-2 expression in fibroblasts, the kidney, and the inner ear of mice.
Laryngeal Neoplasms
A combined modality of carboplatin and photodynamic therapy suppresses epithelial-mesenchymal transition and matrix metalloproteinase-2 (MMP-2)/MMP-9 expression in HEp-2 human laryngeal cancer cells via ROS-mediated inhibition of MEK/ERK signalling pathway.
Laryngeal Neoplasms
Activity of matrix metalloproteinases-2 and -9 in advanced laryngeal cancer.
Laryngeal Neoplasms
Expression of type IV collagen and matrix metalloproteinase-2 (type IV collagenase) in relation to nodal status in laryngeal cancer.
Laryngeal Neoplasms
Matrix metalloproteinase 2 (MMP2) protein expression and laryngeal cancer prognosis: a meta analysis.
Laryngeal Neoplasms
Matrix metalloproteinases (MMPs) and inhibitor of metalloproteinases (TIMP) mRNA and protein expression in laryngeal squamous cell carcinoma.
Laryngeal Neoplasms
Overexpression of MMP-2 in laryngeal squamous cell carcinoma: a potential indicator for poor prognosis.
Laryngeal Neoplasms
Pituitary tumor-transforming 1 expression in laryngeal cancer and its association with prognosis.
Laryngeal Neoplasms
SOX2 promotes the migration and invasion of laryngeal cancer cells by induction of MMP-2 via the PI3K/Akt/mTOR pathway.
Laryngeal Neoplasms
[Role of siRNA mediated matrix metalloproteinase-2 gene silencing in the inhibition of invasion and growth of laryngeal cancer cells]
Laryngeal Neoplasms
[The experimental investigation of the invasion and growth of laryngeal cancer by matrix metalloproteinase-2 and matrix metalloproteinase-9 gene silence together]
Laryngitis
[Expressions of CD147, MMP-2 and MMP-9 in laryngeal carcinoma and clinical significance]
Leg Ulcer
Effect of oxidised regenerated cellulose/collagen matrix on proteases in wound exudate of patients with chronic venous ulceration.
Leg Ulcer
Elevated expression of extracellular matrix metalloproteinase inducer (CD147) and membrane-type matrix metalloproteinases in venous leg ulcers.
Leg Ulcer
Mitogenic bovine whey extract modulates matrix metalloproteinase-2, -9, and tissue inhibitor of matrix metalloproteinase-2 levels in chronic leg ulcers.
Leg Ulcer
The direct inhibition of MMP-2 and MMP-9 by an enzyme alginogel: a possible mechanism of healing support for venous leg ulcers.
Leg Ulcer
The Impact of Differential Expression of Extracellular Matrix Metalloproteinase Inducer, Matrix Metalloproteinase-2, Tissue Inhibitor of Matrix Metalloproteinase-2 and PDGF-AA on the Chronicity of Venous Leg Ulcers.
Leg Ulcer
The role of the urokinase-type plasminogen activator (uPA) and its receptor (CD87) in lipodermatosclerosis.
Leg Ulcer
Wound fluid from chronic leg ulcers contains elevated levels of metalloproteinases MMP-2 and MMP-9.
Leiomyoma
Activity of matrix metalloproteinase-2 and -9 and contents of their tissue inhibitors in uterine leiomyoma and corresponding myometrium.
Leiomyoma
Differential effects of tumor necrosis factor-? on matrix metalloproteinase-2 expression in human myometrial and uterine leiomyoma smooth muscle cells.
Leiomyoma
Differential expression of matrix metalloproteinases and their tissue inhibitors in leiomyomata: a mechanism for gonadotrophin releasing hormone agonist-induced tumour regression.
Leiomyoma
Expression of matrix metalloproteinases in patients with uterine smooth muscle tumors: an immunohistochemical analysis of MMP-1 and MMP-2 protein expression in leiomyoma, uterine smooth muscle tumor of uncertain malignant potential, and leiomyosarcoma.
Leiomyoma
Expression of vascular endothelial factor-A, gelatinases (MMP-2, MMP-9) and TIMP-1 in uterine leiomyomas.
Leiomyoma
Lichong decoction reduces Matrix Metalloproteinases-2 expression but increases Tissue Inhibitors of Matrix Metalloproteinases-2 expression in a rat model of uterine leiomyoma.
Leiomyoma
MicroRNA 21a-5p overexpression impacts mediators of extracellular matrix formation in uterine leiomyoma.
Leiomyoma
Progesterone receptor modulator CDB-2914 induces extracellular matrix metalloproteinase inducer in cultured human uterine leiomyoma cells.
Leiomyoma
Vitamin D3 inhibits expression and activities of matrix metalloproteinase-2 and -9 in human uterine fibroid cells.
Leiomyoma
[The expression of MMP-2, -9 in the uterine leiomyoma and its significance in prognosis].
Leiomyosarcoma
Expression of matrix metalloproteinases in patients with uterine smooth muscle tumors: an immunohistochemical analysis of MMP-1 and MMP-2 protein expression in leiomyoma, uterine smooth muscle tumor of uncertain malignant potential, and leiomyosarcoma.
Leiomyosarcoma
MMP-1 and MMP-2 expression in uterine leiomyosarcoma and correlation with different clinicopathologic parameters.
Leiomyosarcoma
Modulation of u-PA, MMPs and their inhibitors by a novel nutrient mixture in adult human sarcoma cell lines.
Leishmaniasis
Canine cerebral leishmaniasis: Potential role of matrix metalloproteinase-2 in the development of neurological disease.
Leishmaniasis, Cutaneous
Therapeutic failure in American cutaneous leishmaniasis is associated with gelatinase activity and cytokine expression.
Leishmaniasis, Visceral
Canine cerebral leishmaniasis: Potential role of matrix metalloproteinase-2 in the development of neurological disease.
Leishmaniasis, Visceral
Differential alterations in the activity of matrix metalloproteinases within the nervous tissue of dogs in distinct manifestations of visceral leishmaniasis.
Leishmaniasis, Visceral
Expression of matrix metalloproteinase-2 and metalloproteinase-9 in the skin of dogs with visceral leishmaniasis.
Leishmaniasis, Visceral
Levels of Matrix Metalloproteinase-2 and -9 in the Cerebrospinal Fluid of Dogs with Visceral Leishmaniasis.
Lentivirus Infections
LncRNA-HCG18 regulates the viability, apoptosis, migration, invasion and epithelial-mesenchymal transition of papillary thyroid cancer cells via regulating the miR-106a-5p/PPP2R2A axis.
Lentivirus Infections
Potential suppression of the high glucose and insulin-induced retinal neovascularization by Sirtuin 3 in the human retinal endothelial cells.
Leprosy
Expression of metalloproteinases (MMP-2, MMP-9, and TACE) and TNF-alpha in the nerves of leprosy patients.
Leptospirosis
Neutrophil Gelatinase Associated Lipocalin (NGAL) in Leptospirosis Acute Kidney Injury: A Multicenter Study in Thailand.
Leukemia
A possible role of 92 kDa type IV collagenase in the extramedullary tumor formation in leukemia.
Leukemia
Activation of collagenase IV gene expression and enzymatic activity by the Moloney murine leukemia virus long terminal repeat.
Leukemia
Amsacrine suppresses matrix metalloproteinase-2 (MMP-2)/MMP-9 expression in human leukemia cells.
Leukemia
Association of Matrix Metallopeptidase-2 Promoter Polymorphisms With the Risk of Childhood Leukemia.
Leukemia
Autocrine regulation of matrix metalloproteinase-9 gene expression and secretion by tumor necrosis factor-alpha (TNF-alpha) in NB4 leukemic cells: specific involvement of TNF receptor type 1.
Leukemia
Caffeine induces matrix metalloproteinase-2 (MMP-2) and MMP-9 down-regulation in human leukemia U937 cells via Ca(2+)/ROS-mediated suppression of ERK/c-fos pathway and activation of p38 MAPK/c-jun pathway.
Leukemia
CIL-102 induces matrix metalloproteinase-2 (MMP-2)/MMP-9 down-regulation via simultaneous suppression of genetic transcription and mRNA stability.
Leukemia
Effects of AG490 and S3I-201 on regulation of the JAK/STAT3 signaling pathway in relation to angiogenesis in TRAIL-resistant prostate cancer cells in vitro.
Leukemia
Enhanced invasiveness of drug-resistant acute myeloid leukemia cells through increased expression of matrix metalloproteinase-2.
Leukemia
Freshly isolated osteoarthritic chondrocytes are catabolically more active than normal chondrocytes, but less responsive to catabolic stimulation with interleukin-1beta.
Leukemia
Gallic acid downregulates matrix metalloproteinase-2 (MMP-2) and MMP-9 in human leukemia cells with expressed Bcr/Abl.
Leukemia
High molecular weight hyaluronic acid down-regulates the gene expression of osteoarthritis-associated cytokines and enzymes in fibroblast-like synoviocytes from patients with early osteoarthritis.
Leukemia
Is dual inhibition of metalloenzymes HDAC-8 and MMP-2 a potential pharmacological target to combat hematological malignancies?
Leukemia
Leukemic cells (HL-60) produce a novel extracellular matrix-degrading proteinase that is not inhibited by tissue inhibitors of matrix metalloproteinases (TIMPs).
Leukemia
Matrix metalloproteinase-2 and -9 secreted by leukemic cells increase the permeability of blood-brain barrier by disrupting tight junction proteins.
Leukemia
Mutations that abrogate transactivational activity of the feline leukemia virus long terminal repeat do not affect virus replication.
Leukemia
No correlation between pinopode formation and LIF and MMP2 expression in endometrium during implantation window.
Leukemia
Overexpression of amyloid precursor protein in acute myeloid leukemia enhances extramedullary infiltration by MMP-2.
Leukemia
Peroxisome proliferator activated receptor-gamma ligands induced cell growth inhibition and its influence on matrix metalloproteinase activity in human myeloid leukemia cells.
Leukemia
Procyanidin oligomers from Japanese quince (Chaenomeles japonica) fruit inhibit activity of MMP-2 and MMP-9 metalloproteinases.
Leukemia
Regulation of 92-kD gelatinase release in HL-60 leukemia cells: tumor necrosis factor-alpha as an autocrine stimulus for basal- and phorbol ester-induced secretion.
Leukemia
Resveratrol enhances anticancer effects of paclitaxel in HepG2 human liver cancer cells.
Leukemia
Simvastatin induces NF?B/p65 down-regulation and JNK1/c-Jun/ATF-2 activation, leading to matrix metalloproteinase-9 (MMP-9) but not MMP-2 down-regulation in human leukemia cells.
Leukemia
Synthetic emmprin peptides inhibit tumor cell-fibroblast interaction-stimulated upregulation of MMP-2 and tumor cell invasion.
Leukemia
The essential roles of matrix metalloproteinase-2, membrane type 1 metalloproteinase and tissue inhibitor of metalloproteinase-2 in the invasive capacity of acute monocytic leukemia SHI-1 cells.
Leukemia
Tumor necrosis factor alpha and lymphotoxin stimulate human myeloblastic leukemia cell (ML-1) invasion through a reconstituted basement membrane (Matrigel) with concomitant induction of 92 kDa gelatinase secretion.
Leukemia
[Acetyl-11-keto-beta-boswellic acid and arsenic trioxide regulate the productions and activities of matrix metalloproteinases in human skin fibroblasts and human leukemia cell line THP-1].
Leukemia
[Effect of glycyrrhetinic acid on invasive capacity of leukemic cells and activity of gelatinase]
Leukemia
[Effect of TIMP-2, MT1-MMP and MMP-2 expression on the in vitro invasive capacity of acute monocytic leukemia SHI-1 cells.]
Leukemia
[Expression of gelatinase A and B in cord blood CD34+ cells and leukemic cell lines]
Leukemia
[Expression of nuclear factor-kappaB in bone marrow cells from patients with acute leukemia and its relationship with P21, MMP-2 and MMP-9]
Leukemia
[High tumorigenicity of human acute monocytic leukemic cell Line SHI-1 in nude mice and its mechanism]
Leukemia
[Inhibition effect of short hairpin RNA on VEGF receptor flt-1 gene expression in leukemia cell line k562]
Leukemia, Erythroblastic, Acute
[Regulation of Ruxolitinib on matrix metalloproteinase in JAK2V617F positive myeloroliferative neoplasms cells].
Leukemia, Feline
Feline leukemia virus long terminal repeat activates collagenase IV gene expression through AP-1.
Leukemia, Feline
Long terminal repeat regions from exogenous but not endogenous feline leukemia viruses transactivate cellular gene expression.
Leukemia, Feline
Mutations that abrogate transactivational activity of the feline leukemia virus long terminal repeat do not affect virus replication.
Leukemia, Lymphocytic, Chronic, B-Cell
A catalytically inactive gelatinase B/MMP-9 mutant impairs homing of chronic lymphocytic leukemia cells by altering migration regulatory pathways.
Leukemia, Lymphocytic, Chronic, B-Cell
Overexpression of progelatinase B/proMMP-9 affects migration regulatory pathways and impairs chronic lymphocytic leukemia cell homing to bone marrow and spleen.
Leukemia, Monocytic, Acute
The essential roles of matrix metalloproteinase-2, membrane type 1 metalloproteinase and tissue inhibitor of metalloproteinase-2 in the invasive capacity of acute monocytic leukemia SHI-1 cells.
Leukemia, Monocytic, Acute
[Acetyl-11-keto-beta-boswellic acid and arsenic trioxide regulate the productions and activities of matrix metalloproteinases in human skin fibroblasts and human leukemia cell line THP-1].
Leukemia, Monocytic, Acute
[Effect of TIMP-2, MT1-MMP and MMP-2 expression on the in vitro invasive capacity of acute monocytic leukemia SHI-1 cells.]
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
A pentanoic acid derivative targeting matrix metalloproteinase-2 (MMP-2) induces apoptosis in a chronic myeloid leukemia cell line.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Cancer/Testis Antigens: Expression, Regulation, Tumor Invasion, and Use in Immunotherapy of Cancers.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Characteristics of 92 kDa type IV collagenase/gelatinase produced by granulocytic leukemia cells: structure, expression of cDNA in E. coli and enzymic properties.
Leukemia, Myeloid
A possible role of 92 kDa type IV collagenase in the extramedullary tumor formation in leukemia.
Leukemia, Myeloid
All-Trans Retinoic Acid Enhances Matrix Metalloproteinase 2 Expression and Secretion in Human Myeloid Leukemia THP-1 Cells.
Leukemia, Myeloid
Characteristics of 92 kDa type IV collagenase/gelatinase produced by granulocytic leukemia cells: structure, expression of cDNA in E. coli and enzymic properties.
Leukemia, Myeloid
Correlation in the expression of type IV collagenase and the invasive and chemotactic abilities of myelomonocytic cells during differentiation into macrophages.
Leukemia, Myeloid
Peroxisome proliferator activated receptor-gamma ligands induced cell growth inhibition and its influence on matrix metalloproteinase activity in human myeloid leukemia cells.
Leukemia, Myeloid, Acute
Enhanced invasiveness of drug-resistant acute myeloid leukemia cells through increased expression of matrix metalloproteinase-2.
Leukemia, Myeloid, Acute
Expression of the active form of MMP-2 on the surface of leukemic cells accounts for their in vitro invasion.
Leukemia, Myeloid, Acute
Overexpression of amyloid precursor protein in acute myeloid leukemia enhances extramedullary infiltration by MMP-2.
Leukemia, Myeloid, Acute
Secretion and Expression of Matrix Metalloproteinase-2 and 9 from Bone Marrow Mononuclear Cells in Myelodysplastic Syndrome and Acute Myeloid Leukemia.
Leukemia, Myeloid, Acute
The Hematopoietic Microenvironment: Matrix Metalloproteinases in the Hematopoietic Microenvironment.
Leukemia, Myeloid, Acute
[Activity of matrix metalloproteinases MMP-2 and MMP-9 in bone marrow plasma of patients with acute myeloid leukemia].
Leukemia, Myeloid, Acute
[Relationship between VEGF and MMP-2, MMP-9 in 82 Patients with Acute Myeloid Leukemia.]
Leukemia, Promyelocytic, Acute
Autocrine regulation of matrix metalloproteinase-9 gene expression and secretion by tumor necrosis factor-alpha (TNF-alpha) in NB4 leukemic cells: specific involvement of TNF receptor type 1.
Leukocytosis
Neutrophil gelatinase B and chemokines in leukocytosis and stem cell mobilization.
Leukoplakia
Matrix metalloproteinase-2 matrix metalloproteinase-9 and inducible nitric oxide synthase in oral leukoplakia: immunohistochemistry and RT-PCR analysis.
Leukoplakia, Oral
Changes in the expression of Col IV, gelatinase and TIMP-1 in oral leukoplakia.
Leukoplakia, Oral
Matrix metalloproteinase-2 matrix metalloproteinase-9 and inducible nitric oxide synthase in oral leukoplakia: immunohistochemistry and RT-PCR analysis.
Lichen Planus
Expression of matrix metalloproteinases (MMP-1 and -2) and their inhibitors (TIMP-1, -2 and -3) in oral lichen planus, dysplasia, squamous cell carcinoma and lymph node metastasis.
Lichen Planus, Oral
Correlation of VEGF and MMP-2 levels in oral lichen planus: An in vivo immunohistochemical study.
Lichen Planus, Oral
Immunohistochemical and clinical significance of matrix metalloproteinase-2 and its inhibitor in oral lichen planus.
Lichen Planus, Oral
miR-125b inhibits keratinocyte proliferation and promotes keratinocyte apoptosis in oral lichen planus by targeting MMP-2 expression through PI3K/Akt/mTOR pathway.
Lichen Planus, Oral
MMPs, TIMP-2, and TGF-beta1 in the cancerization of oral lichen planus.
Lichen Planus, Oral
Salivary MMP-1, MMP-2, MMP-3 and MMP-13 Levels in Patients with Oral Lichen Planus and Squamous Cell Carcinoma
Lichen Planus, Oral
[The role of matrix metalloproteinases and their tissue inhibitors in oral lichen planus]
Lipodystrophy
Didanosine (ddI) associates with increased liver fibrosis in adult HIV-HCV coinfected patients.
Lipodystrophy
Modulation of Systemic Metabolism by MMP-2: From MMP-2 Deficiency in Mice to MMP-2 Deficiency in Patients.
Liposarcoma
In vitro modulation of MMP-2 and MMP-9 in adult human sarcoma cell lines by cytokines, inducers and inhibitors.
Liposarcoma
Modulation of u-PA, MMPs and their inhibitors by a novel nutrient mixture in adult human sarcoma cell lines.
Liver Cirrhosis
Acetaldehyde regulates the gene expression of matrix-metalloproteinase-1 and -2 in human fat-storing cells.
Liver Cirrhosis
Activity of MMP-2, MMP-8 and MMP-9 in serum as a marker of progression of alcoholic liver disease in people from Lublin Region, eastern Poland.
Liver Cirrhosis
Adenoviral delivery of dominant-negative transforming growth factor beta type II receptor up-regulates transcriptional repressor SKI-like oncogene, decreases matrix metalloproteinase 2 in hepatic stellate cell and prevents liver fibrosis in rats.
Liver Cirrhosis
Aldose reductase is involved in the development of murine diet-induced nonalcoholic steatohepatitis.
Liver Cirrhosis
An herbal formula, CGX, exerts hepatotherapeutic effects on dimethylnitrosamine-induced chronic liver injury model in rats.
Liver Cirrhosis
Antifibrotic effects of a tissue inhibitor of metalloproteinase-1 antibody on established liver fibrosis in rats.
Liver Cirrhosis
Cholestatic liver fibrosis and toxin-induced fibrosis are exacerbated in matrix metalloproteinase-2 deficient mice.
Liver Cirrhosis
Circulating matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-1 as serum markers of fibrosis in patients with chronic hepatitis C. Relationship to interferon response.
Liver Cirrhosis
Clinical implication of vascular cell adhesion molecule-1 and very late activation antigen-4 interaction, and matrix metalloproteinase-2 production in patients with liver disease.
Liver Cirrhosis
Clinical significance of serum matrix metalloproteinases and tissue inhibitors of metalloproteinases in chronic liver disease.
Liver Cirrhosis
Clinical usefulness of serum matrix metalloproteinase-2 concentration in patients with chronic viral liver disease.
Liver Cirrhosis
Clinical utility of serum matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 concentrations in the assessment of liver fibrosis due to chronic hepatitis B.
Liver Cirrhosis
Combined use of aspartate aminotransferase, platelet count and matrix metalloproteinase 2 measurements to predict liver fibrosis in HIV/hepatitis C virus-coinfected patients.
Liver Cirrhosis
Deficiency in myeloid differentiation factor-2 and toll-like receptor 4 expression attenuates nonalcoholic steatohepatitis and fibrosis in mice.
Liver Cirrhosis
Deficiency of inducible nitric oxide synthase exacerbates hepatic fibrosis in mice fed high-fat diet.
Liver Cirrhosis
Diagnostic potential of circulating TIMP-1 and MMP-2 as markers of liver fibrosis in patients with chronic hepatitis C.
Liver Cirrhosis
Diagnostic potential of serum matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-1 as non-invasive markers of hepatic fibrosis in patients with HCV related chronic liver disease.
Liver Cirrhosis
Disruption of tissue-type plasminogen activator gene in mice aggravated liver fibrosis.
Liver Cirrhosis
Dual expression of matrix metalloproteinase-2 and membrane-type 1-matrix metalloproteinase in fibrotic human livers.
Liver Cirrhosis
Dynamic change of cells expressing MMP-2 mRNA and MT1-MMP mRNA in the recovery from liver fibrosis in the rat.
Liver Cirrhosis
Effect of antiviral therapy on markers of fibrogenesis in patients with chronic hepatitis C.
Liver Cirrhosis
Effects of alcohol consumption on eight circulating markers of liver fibrosis.
Liver Cirrhosis
Enhanced efficacy of curcumin with phosphatidylserine-decorated nanoparticles in the treatment of hepatic fibrosis.
Liver Cirrhosis
Evaluation of matrix metalloproteinases and their endogenous tissue inhibitors in biliary atresia-associated liver fibrosis.
Liver Cirrhosis
Expression of matrix metalloproteinase-2 and -14 persists during early resolution of experimental liver fibrosis and might contribute to fibrolysis.
Liver Cirrhosis
Fibrogenesis II. Metalloproteinases and their inhibitors in liver fibrosis.
Liver Cirrhosis
Fraxinus rhynchophylla ethanol extract attenuates carbon tetrachloride-induced liver fibrosis in rats via down-regulating the expressions of uPA, MMP-2, MMP-9 and TIMP-1.
Liver Cirrhosis
Heparanase expression during normal liver development and following partial hepatectomy.
Liver Cirrhosis
HIF-1 ? as a Key Factor in Bile Duct Ligation-Induced Liver Fibrosis in Rats.
Liver Cirrhosis
Inhibition of Cyclic Adenosine Monophosphate (cAMP)-response Element-binding Protein (CREB)-binding Protein (CBP)/?-Catenin Reduces Liver Fibrosis in Mice.
Liver Cirrhosis
Inhibition of liver fibrosis using vitamin A-coupled liposomes to deliver matrix metalloproteinase-2 siRNA in vitro.
Liver Cirrhosis
Liver fibrosis improvement in chronic hepatitis C after direct acting-antivirals is accompanied by reduced profibrogenic biomarkers-a role for MMP-9/TIMP-1.
Liver Cirrhosis
Loss of Matrix Metalloproteinase-2 Amplifies Murine Toxin-Induced Liver Fibrosis by Upregulating Collagen I Expression.
Liver Cirrhosis
Matrilysin (MMP-7) is a major matrix metalloproteinase upregulated in biliary atresia-associated liver fibrosis.
Liver Cirrhosis
Matrix metalloproteases and their tissue inhibitors in non-alcoholic liver fibrosis of human immunodeficiency virus-infected patients.
Liver Cirrhosis
Matrix Metalloproteinase-13 Promotes Recovery from Experimental Liver Cirrhosis in Rats.
Liver Cirrhosis
Matrix metalloproteinase-2 activation in human hepatic fibrosis regulation by cell-matrix interactions.
Liver Cirrhosis
Matrix Metalloproteinases (MMPs) Activity in Cultured Canine Bone Marrow Stromal Cells (BMSCs).
Liver Cirrhosis
Matrix metalloproteinases and their tissue inhibitors in children with chronic hepatitis B treated with lamivudine.
Liver Cirrhosis
MMP mediated degradation of type VI collagen is highly associated with liver fibrosis--identification and validation of a novel biochemical marker assay.
Liver Cirrhosis
Modified synthetic siRNA targeting tissue inhibitor of metalloproteinase-2 inhibits hepatic fibrogenesis in rats.
Liver Cirrhosis
Naringenin loaded multifunctional nanoparticles to enhance the chemotherapeutic efficacy in hepatic fibrosis.
Liver Cirrhosis
Neutrophil Gelatinase Associated Lipocalin (NGAL) - a biomarker of renal dysfunction in patients with liver cirrhosis: Do we have enough proof?
Liver Cirrhosis
Plasma levels of matrix metalloproteinase-2 and -9 in male and female patients with cirrhosis of different aetiologies.
Liver Cirrhosis
Production of pro- and anti-fibrotic agents by rat Kupffer cells; the effect of octreotide.
Liver Cirrhosis
Resolution of liver fibrosis by isoquinoline alkaloid berberine in CCl?-intoxicated mice is mediated by suppression of oxidative stress and upregulation of MMP-2 expression.
Liver Cirrhosis
Role of MMP-2 and MMP-9 and their natural inhibitors in liver fibrosis, chronic pancreatitis and non-specific inflammatory bowel diseases.
Liver Cirrhosis
The anti-fibrotic effect of pirfenidone in rat liver fibrosis is mediated by downregulation of procollagen alpha1(I), TIMP-1 and MMP-2.
Liver Cirrhosis
The Clinical Significance of Serum Apoptotic Cytokeratin 18 Neoepitope M30 (CK-18 M30) and Matrix Metalloproteinase 2 (MMP-2) Levels in Chronic Hepatitis B Patients with Cirrhosis.
Liver Cirrhosis
The effect of Ras inhibition on the proliferation, apoptosis and matrix metalloproteases activity in rat hepatic stellate cells.
Liver Cirrhosis
The selective cyclooxygenase-2 inhibitor SC-236 reduces liver fibrosis by mechanisms involving non-parenchymal cell apoptosis and PPARgamma activation.
Liver Cirrhosis
The use of low molecular weight heparin-pluronic nanogels to impede liver fibrosis by inhibition the TGF-?/Smad signaling pathway.
Liver Cirrhosis
Usefulness of non-invasive markers for predicting liver cirrhosis in patients with chronic hepatitis B.
Liver Cirrhosis
[Clinical usefulness of plasma activities of gelatinase (matrix metalloproteinase-2 and 9) in chronic liver disease]
Liver Cirrhosis
[Dynamic evolution of MMP-2 gene expression and its enzymatic activities in experimental liver fibrosis]
Liver Cirrhosis
[Effect of oxymatrine on serum matrix metalloproteinase-2 and its inhibitor in patients with chronic hepatitis B and liver cirrhosis]
Liver Cirrhosis
[Effect of TGFbeta1 vaccine on the expression of MMP-2 and TIMP-2 in rats with liver fibrosis.]
Liver Cirrhosis
[Effects of salvianolic acid B on lipid peroxidation and metalloproteinase-2 activity in fibrotic liver in rat]
Liver Cirrhosis
[Expression of matrix metalloproteinase 2 and 9 in liver tissue of patients with schistosomiasis japonica]
Liver Cirrhosis
[Serum markers of fibrosis and endothelial dysfunction in patients with alcoholism, with varying degrees of liver fibrosis].
Liver Cirrhosis
[The effect of herbal compound 861 on mRNA levels of MMP-2 and its activities in experimental rats liver fibrosis]
Liver Cirrhosis
[The role of changes of MMP-2, 9 activity in the development of liver fibrosis in rats]
Liver Cirrhosis, Alcoholic
Activity of MMP-2, MMP-8 and MMP-9 in serum as a marker of progression of alcoholic liver disease in people from Lublin Region, eastern Poland.
Liver Cirrhosis, Alcoholic
The decrease of serum MMP-2 activity corresponds to alcoholic cirrhosis stage.
Liver Diseases
Assessment of serum matrix metalloproteinases MMP-2 and MMP-9 after human liver transplantation: increased serum MMP-9 level in acute rejection.
Liver Diseases
Assessment of the clinical significance of serum matrix metalloproteinases MMP-2 and MMP-9 in patients with various chronic liver diseases and hepatocellular carcinoma.
Liver Diseases
Circulating gelatinases and tissue inhibitor of metalloproteinase-1 in colorectal cancer metastatic liver disease.
Liver Diseases
Clinical and prognostic role of matrix metalloproteinase-2, -9 and their inhibitors in breast cancer and liver diseases: A review.
Liver Diseases
Clinical Benefits of Biochemical Markers of Fibrosis in Egyptian Children With Chronic Liver Diseases.
Liver Diseases
Clinical implication of vascular cell adhesion molecule-1 and very late activation antigen-4 interaction, and matrix metalloproteinase-2 production in patients with liver disease.
Liver Diseases
Clinical significance of serum matrix metalloproteinases and tissue inhibitors of metalloproteinases in chronic liver disease.
Liver Diseases
Clinical usefulness of serum matrix metalloproteinase-2 concentration in patients with chronic viral liver disease.
Liver Diseases
Diagnostic potential of serum matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-1 as non-invasive markers of hepatic fibrosis in patients with HCV related chronic liver disease.
Liver Diseases
Differential expression of matrix-metalloproteinase-1 and -2 genes in normal and fibrotic human liver.
Liver Diseases
Expression of matrix metalloproteinase-2 and -9 and their inhibitors in peripheral blood cells of patients with chronic hepatitis C.
Liver Diseases
Higher hepatic gene expression and serum levels of matrix metalloproteinase-2 are associated with steatohepatitis in non-alcoholic fatty liver diseases.
Liver Diseases
Increased intrahepatic cyclooxygenase 2, matrix metalloproteinase 2, and matrix metalloproteinase 9 expression is associated with progressive liver disease in chronic hepatitis C virus infection: role of viral core and NS5A proteins.
Liver Diseases
Interactions of central obesity with rs3918242 on risk of non-alcoholic fat liver disease: a preliminary case-control study.
Liver Diseases
Loss of Matrix Metalloproteinase-2 Amplifies Murine Toxin-Induced Liver Fibrosis by Upregulating Collagen I Expression.
Liver Diseases
Plasma Levels of Matrix Metalloproteinase (MMP)-2, MMP-9 and Tumor Necrosis Factor-? in Chronic Hepatitis C Virus Patients.
Liver Diseases
Plasma levels of matrix metalloproteinase-2 (MMP-2) and tissue inhibitors of metalloproteinases -1 and -2 (TIMP-1 and TIMP-2) as noninvasive markers of liver disease in chronic hepatitis C: comparison using ROC analysis.
Liver Diseases
Relationship between matrix metalloproteinase-2 activity and cystatin C levels in patients with hepatic disease.
Liver Diseases
Serum levels of tissue inhibitor of metalloproteinases-2 and of precursor form of matrix metalloproteinase-2 in patients with liver disease.
Liver Diseases
[Clinical usefulness of plasma activities of gelatinase (matrix metalloproteinase-2 and 9) in chronic liver disease]
Liver Diseases, Alcoholic
Activity of MMP-2, MMP-8 and MMP-9 in serum as a marker of progression of alcoholic liver disease in people from Lublin Region, eastern Poland.
Liver Diseases, Alcoholic
[Dynamic change and expression of matrix metalloproteinase-2, -9 in alcoholic liver disease in rats]
Liver Neoplasms
Atractylon induces apoptosis and suppresses metastasis in hepatic cancer cells and inhibits growth in vivo.
Liver Neoplasms
Contribution of Nitric Oxide and Epidermal Growth Factor Receptor in Anti-Metastatic Potential of Paclitaxel in Human Liver Cancer Cell (HebG2).
Liver Neoplasms
Effects of siRNA-targeting BMP-2 on the abilities of migration and invasion of human liver cancer SMMC7721 cells and its mechanism.
Liver Neoplasms
Expression and clinical significance of HMGB1 in human liver cancer: Knockdown inhibits tumor growth and metastasis in vitro and in vivo.
Liver Neoplasms
Inhibitory effect of bufalin combined with Hedgehog signaling pathway inhibitors on proliferation and invasion and metastasis of liver cancer cells.
Liver Neoplasms
Isolation of Fibroblast-Activation Protein-Specific Cancer-Associated Fibroblasts.
Liver Neoplasms
MiR-129-2 weakens proliferation and promotes apoptosis of liver cancer cells by suppressing the Wnt signaling pathway.
Liver Neoplasms
Patients with hepatic breast cancer metastases demonstrate highly specific profiles of matrix metalloproteinases MMP-2 and MMP-9 after SIRT treatment as compared to other primary and secondary liver tumours.
Liver Neoplasms
Plumbagin inhibits invasion and migration of liver cancer HepG2 cells by decreasing productions of matrix metalloproteinase-2 and urokinase- plasminogen activator.
Liver Neoplasms
Silymarin attenuated mast cell recruitment thereby decreased the expressions of matrix metalloproteinases-2 and 9 in rat liver carcinogenesis.
Liver Neoplasms
Sonic Hedgehog signaling pathway induces cell migration and invasion through focal adhesion kinase/AKT signaling-mediated activation of matrix metalloproteinase (MMP)-2 and MMP-9 in liver cancer.
Liver Neoplasms
The Protein Extract of Chlorella minutissima Inhibits The Expression of MMP-1, MMP-2 and MMP-9 in Cancer Cells through Upregulation of TIMP-3 and Down Regulation of c-Jun.
Liver Neoplasms
Ultra-small gold nanoparticles self-assembled by gadolinium ions for enhanced photothermal/photodynamic liver cancer therapy.
Liver Neoplasms
[Effect of Dahuang Zhechong Pills combined with TACE on VEGF, MMP-2, TGF-?1 and immune function of patients with primary liver cancer (blood stasis and collaterals blocking type)].
Lung Diseases
Alpha-1-antitrypsin aerosolised augmentation abrogates neutrophil elastase-induced expression of cathepsin B and matrix metalloprotease 2 in vivo and in vitro.
Lung Diseases
Cigarette smoke exposure inhibits extracellular MMP-2 (gelatinase A) activity in human lung fibroblasts.
Lung Diseases
Elevated expression of MMP-2 and TIMP-2 cooperatively correlates with risk of lung cancer.
Lung Diseases
Exploring the Role of Matrix Metalloproteinases as Biomarkers in Sporadic Lymphangioleiomyomatosis and Tuberous Sclerosis Complex. A Pilot Study.
Lung Diseases
Hyperoxia decreases matrix metalloproteinase-9 and increases tissue inhibitor of matrix metalloproteinase-1 protein in the newborn rat lung: association with arrested alveolarization.
Lung Diseases
Implications for matrix metalloproteinases as modulators of pediatric lung disease.
Lung Diseases
Increased matrix metalloproteinase-2 and membrane type 1 matrix metalloproteinase activity and expression in heterotopically transplanted murine tracheas.
Lung Diseases
Increased production of matrix metalloproteinase-2 in alveolar macrophages and regulation by interleukin-10 in patients with acute pulmonary sarcoidosis.
Lung Diseases
Matrix metalloproteinase-2, -7, and -9 activities in dogs with idiopathic pulmonary fibrosis compared to healthy dogs and dogs with other respiratory diseases.
Lung Diseases
[The changes and effects of metalloproteinase-2 and tissue inhibitors of metalloproteinase-1 protein and mRNA expression in the lung tissue of neonatal rats with chronic lung disease induced by hyperoxia.]
Lung Diseases
[The expression and its clinical significance of MMP-2 and MMP-9 in non-small cell lung cancer.]
Lung Diseases, Interstitial
Extracellular matrix metalloproteinase inducer in interstitial pneumonias.
Lung Diseases, Interstitial
Localization of matrix metalloproteinases-1, -2, and -9 and tissue inhibitor of metalloproteinase-2 in interstitial lung diseases.
Lung Injury
Augmented metalloproteinase activity and acute lung injury in copper-deficient rats.
Lung Injury
Collagenase and gelatinase activities in bronchoalveolar lavage fluids during bleomycin-induced lung injury.
Lung Injury
Impact of Time on Fluid Resuscitation with Hypertonic Saline (NaCl 7.5%) in Rats with LPS-Induced Acute Lung Injury.
Lung Injury
Inhibition of matrix metalloproteinase-2 enhances radiosensitivity by abrogating radiation-induced FoxM1-mediated G2/M arrest in A549 lung cancer cells.
Lung Injury
Ionizing radiation enhances matrix metalloproteinase-2 production in human lung epithelial cells.
Lung Injury
LPS-induced lung injury in neonatal rats: changes in gelatinase activities and consequences on lung growth.
Lung Injury
Matrix metalloproteinase-14 triggers an anti-inflammatory proteolytic cascade in endotoxemia.
Lung Injury
Matrix-Metallo-Proteinases and their tissue inhibitors in radiation-induced lung injury.
Lung Injury
Metalloproteinase inhibition reduces lung injury and improves survival after cecal ligation and puncture in rats.
Lung Injury
Neutrophil proteinases in hydrochloric acid- and endotoxin-induced acute lung injury: evaluation of interstitial protease activity by in situ zymography.
Lung Injury
Pentoxifylline attenuates lung injury and modulates transcription factor activity in hemorrhagic shock.
Lung Injury
Retinoic aacid diminished the expression of MMP-2 in hyperoxia-exposed premature rat lung fibroblasts through regulating mitogen-activated protein kinases.
Lung Injury
Selective PDE4 inhibitors as potent anti-inflammatory drugs for the treatment of airway diseases.
Lung Injury
TGF-betal transgenic mouse model of thoracic irradiation: modulation of MMP-2 and MMP-9 in the lung tissue.
Lung Injury
[Expression of various matrix metalloproteinases in mice with hyperoxia induced acute lung injury.]
Lung Injury
[Retinoic acid diminished the expression of lung tissue matrix metalloproteinase-2 and matrix metalloproteinase-9 in hyperoxia-exposed premature rats through regulating mitogen-activated protein kinases]
Lung Neoplasms
3,4-Dihydroxybenzalactone Suppresses Human Non-Small Cell Lung Carcinoma Cells Metastasis via Suppression of Epithelial to Mesenchymal Transition, ROS-Mediated PI3K/AKT/MAPK/MMP and NF?B Signaling Pathways.
Lung Neoplasms
72-kD (MMP-2) and 92-kD (MMP-9) type IV collagenase production and activity in different histologic types of lung cancer cells.
Lung Neoplasms
A Fra-1-dependent, matrix metalloproteinase driven EGFR activation promotes human lung epithelial cell motility and invasion.
Lung Neoplasms
A functional polymorphism in the matrix metalloproteinase-2 gene promoter (-1306C/T) is associated with risk of development but not metastasis of gastric cardia adenocarcinoma.
Lung Neoplasms
A third-generation matrix metalloproteinase (MMP) inhibitor (ONO-4817) combined with docetaxel suppresses progression of lung micrometastasis of MMP-expressing tumor cells in nude mice.
Lung Neoplasms
Absence of CD9 enhances adhesion-dependent morphologic differentiation, survival, and matrix metalloproteinase-2 production in small cell lung cancer cells.
Lung Neoplasms
Acacetin inhibits TPA-induced MMP-2 and u-PA expressions of human lung cancer cells through inactivating JNK signaling pathway and reducing binding activities of NF-kappaB and AP-1.
Lung Neoplasms
Activating transcription factor 1 promoted migration and invasion in lung cancer cells through regulating EGFR and MMP-2.
Lung Neoplasms
Activity of type IV collagenases (MMP-2 and MMP-9) in primary pulmonary carcinomas: a quantitative analysis.
Lung Neoplasms
Adenovirus-mediated small interfering RNA against matrix metalloproteinase-2 suppresses tumor growth and lung metastasis in mice.
Lung Neoplasms
Angelica sinensis suppresses human lung adenocarcinoma A549 cell metastasis by regulating MMPs/TIMPs and TGF-?1.
Lung Neoplasms
Anti-metastatic effects of isolinderalactone via the inhibition of MMP-2 and up regulation of NM23-H1 expression in human lung cancer A549 cells.
Lung Neoplasms
Anticancer Effects of Valproic Acid via Regulation of Epigenetic Mechanisms in Non-small-cell Lung Cancer A549 Cell Line.
Lung Neoplasms
Aquaporin 1 promotes the proliferation and migration of lung cancer cell in vitro.
Lung Neoplasms
ARHGAP15 regulates lung cancer cell proliferation and metastasis via the STAT3 pathway.
Lung Neoplasms
Assessment of control tissue for gene and protein expression studies: a comparison of three alternative lung sources.
Lung Neoplasms
Association between cyclooxygenase-2 and matrix metalloproteinase-2 expression in non-small cell lung cancer.
Lung Neoplasms
Astragaloside IV increases MMP-2 mRNA and protein expression in human lung cancer A549 cells.
Lung Neoplasms
Autocrine/paracrine prostaglandin E2 production by non-small cell lung cancer cells regulates matrix metalloproteinase-2 and CD44 in cyclooxygenase-2-dependent invasion.
Lung Neoplasms
Berberine hydrochloride inhibits cell proliferation and promotes apoptosis of non-small cell lung cancer via the suppression of the MMP2 and Bcl-2/Bax signaling pathways.
Lung Neoplasms
Biological and clinical significance of MMP-2, MMP-9, TIMP-1 and TIMP-2 in non-small cell lung cancer.
Lung Neoplasms
Bisphenol A stimulates human lung cancer cell migration via upregulation of matrix metalloproteinases by GPER/EGFR/ERK1/2 signal pathway.
Lung Neoplasms
BIX02189 inhibits TGF-?1-induced lung cancer cell metastasis by directly targeting TGF-? type I receptor.
Lung Neoplasms
Cancer/Testis Antigens: Expression, Regulation, Tumor Invasion, and Use in Immunotherapy of Cancers.
Lung Neoplasms
Capn4 promotes non-small cell lung cancer progression via upregulation of matrix metalloproteinase 2.
Lung Neoplasms
Cellular localization of EMMPRIN predicts prognosis of patients with operable lung adenocarcinoma independent from MMP-2 and MMP-9.
Lung Neoplasms
Chemoradiation in Lung Cancer: Effect on Levels of NGAL and Vitamin D in Serum.
Lung Neoplasms
Circulating tumor cells from a 4-dimensional lung cancer model are resistant to cisplatin.
Lung Neoplasms
CK2 inhibitor CX4945 induces sequential inactivation of proteins in the signaling pathways related with cell migration and suppresses metastasis of A549 human lung cancer cells.
Lung Neoplasms
Clinicopathologic significance of ?-catenin and matrix metalloproteinase-2 expression in non-small cell lung cancer.
Lung Neoplasms
Combined therapeutic effect and molecular mechanisms of metformin and cisplatin in human lung cancer xenografts in nude mice.
Lung Neoplasms
Comparative expression of matrix metalloproteinases in internal malignancies and paired cutaneous metastatic lesions.
Lung Neoplasms
Correlation between a single nucleotide polymorphism in the matrix metalloproteinase-2 promoter and risk of lung cancer.
Lung Neoplasms
Correlation between MMP2 expression in lung cancer tissues and clinical parameters: a retrospective clinical analysis.
Lung Neoplasms
Correlation of serum metalloproteinase levels with lung cancer metastasis and response to therapy.
Lung Neoplasms
Curcumin inhibits lung cancer cell migration and invasion through Rac1-dependent signaling pathway.
Lung Neoplasms
Curcumin inhibits the migration and invasion of human A549 lung cancer cells through the inhibition of matrix metalloproteinase-2 and -9 and Vascular Endothelial Growth Factor (VEGF).
Lung Neoplasms
Deficiency of antiproliferative family protein Ana correlates with development of lung adenocarcinoma.
Lung Neoplasms
Degradation of tenascin-C and activity of matrix metalloproteinase-2 are associated with tumor recurrence in early stage non-small cell lung cancer.
Lung Neoplasms
Dehydrocostus Lactone Enhances Chemotherapeutic Potential of Doxorubicin in Lung Cancer by Inducing Cell Death and Limiting Metastasis.
Lung Neoplasms
Derlin-1 Is Overexpressed in Non-Small Cell Lung Cancer and Promotes Cancer Cell Invasion via EGFR-ERK-Mediated Up-Regulation of MMP-2 and MMP-9.
Lung Neoplasms
Dietary flavonoid myricetin inhibits invasion and migration of radioresistant lung cancer cells (A549-IR) by suppressing MMP-2 and MMP-9 expressions through inhibition of the FAK-ERK signaling pathway.
Lung Neoplasms
Differences in Plasma MMPs and TIMPs Protein Expression and Chemotherapy Response in Patients with Tobacco- or Wood-Smoke-Induced Lung Cancer.
Lung Neoplasms
Effect of shRNA Mediated Down-Regulation of Annexin A2 on Biological Behavior of Human Lung Adencarcinoma Cells A549.
Lung Neoplasms
Efficient, enzyme responsive and tumor receptor targeting gelatin nanoparticles decorated with concanavalin-A for site-specific and controlled drug delivery for cancer therapy.
Lung Neoplasms
EGCG inhibits the invasion of highly invasive CL1-5 lung cancer cells through suppressing MMP-2 expression via JNK signaling and induces G2/M arrest.
Lung Neoplasms
Elastin-derived peptides increase invasive capacities of lung cancer cells by post-transcriptional regulation of MMP-2 and uPA.
Lung Neoplasms
Elevated activities of MMP-2 in the non-tumorous lung tissues of curatively resected stage I NSCLC patients are associated with tumor recurrence and a poor survival.
Lung Neoplasms
Elevated expression of MMP-2 and TIMP-2 cooperatively correlates with risk of lung cancer.
Lung Neoplasms
Elevated level of circulating matrix metalloproteinase-9 in patients with lung cancer.
Lung Neoplasms
Estrogen promotes tumor metastasis via estrogen receptor beta-mediated regulation of matrix-metalloproteinase-2 in non-small cell lung cancer.
Lung Neoplasms
Exosomal miR-106b serves as a novel marker for lung cancer and promotes cancer metastasis via targeting PTEN.
Lung Neoplasms
Expression analysis of three miRNAs, miR-26a, miR-29b and miR-519d, in relation to MMP-2 expression level in non-small cell lung cancer patients: a pilot study.
Lung Neoplasms
Expression and the potential functions of TRIM32 in lung cancer tumorigenesis.
Lung Neoplasms
Expression of gelatinase A, tissue inhibitor of metalloproteinases-2, matrilysin, and trypsin(ogen) in lung neoplasms: an immunohistochemical study.
Lung Neoplasms
Expression of matrix metalloproteinases and tissue inhibitor of matrix metalloproteinases in non-small-cell lung cancer.
Lung Neoplasms
Expression of metastasis-associated molecules in non-small cell lung cancer and their prognostic significance.
Lung Neoplasms
Expression of SHP2 and Related Markers in Non-Small Cell Lung Cancer: A Tissue Microarray Study of 80 Cases.
Lung Neoplasms
Expression of type IV collagenase correlates with the expression of vascular endothelial growth factor in primary non-small cell lung cancer.
Lung Neoplasms
Fibulin-3 promoter methylation alters the invasive behavior of non-small cell lung cancer cell lines via MMP-7 and MMP-2 regulation.
Lung Neoplasms
FOXH1 promotes lung cancer progression by activating the Wnt/?-catenin signaling pathway.
Lung Neoplasms
Functional haplotypes in the promoter of matrix metalloproteinase-2 and lung cancer susceptibility.
Lung Neoplasms
Gaseous nitrogen oxide promotes human lung cancer cell line A549 migration, invasion, and metastasis via iNOS-mediated MMP-2 production.
Lung Neoplasms
Gelatin-degrading type IV collagenase isolated from human small cell lung cancer.
Lung Neoplasms
Gelatinolytic activity of matrix metalloproteinase in lung cancer studied using film in situ zymography stamp method.
Lung Neoplasms
Genetic polymorphisms in MMP 2, 9 and 3 genes modify lung cancer risk and survival.
Lung Neoplasms
Genetic polymorphisms of matrix metalloproteinases in lung, breast and colorectal cancer.
Lung Neoplasms
GOLPH3 Overexpression is Closely Correlated with Poor Prognosis in Human Non-Small Cell Lung Cancer and Mediates its Metastasis Through Upregulating MMP-2 and MMP-9.
Lung Neoplasms
Granulocyte, granulocyte-macrophage, and macrophage colony-stimulating factors can stimulate the invasive capacity of human lung cancer cells.
Lung Neoplasms
Growth factor-enhanced expression and activity of matrix metalloproteases in human non-small cell lung cancer cell lines.
Lung Neoplasms
High Mobility Group Box Protein 1 Serves as a Potential Prognostic Marker of Lung Cancer and Promotes Its Invasion and Metastasis by Matrix Metalloproteinase-2 in a Nuclear Factor-?B-Dependent Manner.
Lung Neoplasms
Human papillomavirus up-regulates MMP-2 and MMP-9 expression and activity by inducing interleukin-8 in lung adenocarcinomas.
Lung Neoplasms
ICAM-3 enhances the migratory and invasive potential of human non-small cell lung cancer cells by inducing MMP-2 and MMP-9 via Akt and CREB.
Lung Neoplasms
IDH-Inhibiting Small Molecule DTDQ Inhibits Migration and Invasion of A549 Human Non-Small-Cell Lung Cancer Cells via Sequential Inactivation Of ERK and P38 Signaling Pathways.
Lung Neoplasms
IL-17A/IL-17RA promotes invasion and activates MMP-2 and MMP-9 expression via p38 MAPK signaling pathway in non-small cell lung cancer.
Lung Neoplasms
Increased expression of matrix metalloproteinase-2 (MMP-2) predicts tumour recurrence and unfavourable outcome in non-small cell lung cancer.
Lung Neoplasms
Influence of MMP-2 and MMP-9 promoter polymorphisms on gene expression and clinical outcome of non-small cell lung cancer.
Lung Neoplasms
Inhibition of matrix metalloproteinase-2 enhances radiosensitivity by abrogating radiation-induced FoxM1-mediated G2/M arrest in A549 lung cancer cells.
Lung Neoplasms
Inhibitory effect of berberine on the invasion of human lung cancer cells via decreased productions of urokinase-plasminogen activator and matrix metalloproteinase-2.
Lung Neoplasms
Integrin ?v?6 Promotes Lung Cancer Proliferation and Metastasis through Upregulation of IL-8-Mediated MAPK/ERK Signaling.
Lung Neoplasms
Intracellular expression of a single-chain antibody directed against type IV collagenase inhibits the growth of lung cancer xenografts in nude mice.
Lung Neoplasms
Is a single nucleotide polymorphism a risk factor for lung cancer in the matrix metalloproteinase-2 promoter?
Lung Neoplasms
Kaempferol Suppresses Transforming Growth Factor-?1-Induced Epithelial-to-Mesenchymal Transition and Migration of A549 Lung Cancer Cells by Inhibiting Akt1-Mediated Phosphorylation of Smad3 at Threonine-179.
Lung Neoplasms
MAG-2 promotes invasion, mobility and adherence capability of lung cancer cells by MMP-2, CD44 and intracellular calcium in vitro.
Lung Neoplasms
Matrix metalloproteinase 2 polymorphisms and expression in lung cancer: a meta-analysis.
Lung Neoplasms
Matrix metalloproteinase-2 gene polymorphism is not associated with increased glioblastoma multiforme susceptibility: an Indian institutional experience.
Lung Neoplasms
Matrix metalloproteinase-2 polymorphisms and clinical outcome of Chinese patients with nonsmall cell lung cancer treated with first-line, platinum-based chemotherapy.
Lung Neoplasms
Matrix metalloproteinase-2 status in stromal fibroblasts, not in tumor cells, is a significant prognostic factor in non-small-cell lung cancer.
Lung Neoplasms
MED28 and forkhead box M1 (FOXM1) mediate matrix metalloproteinase 2 (MMP2)-dependent cellular migration in human nonsmall cell lung cancer (NSCLC) cells.
Lung Neoplasms
MicroRNA-130b functions as an oncomiRNA in non-small cell lung cancer by targeting tissue inhibitor of metalloproteinase-2.
Lung Neoplasms
MicroRNA-29b attenuates non-small cell lung cancer metastasis by targeting matrix metalloproteinase 2 and PTEN.
Lung Neoplasms
MMP-2 alters VEGF expression via alphaVbeta3 integrin-mediated PI3K/AKT signaling in A549 lung cancer cells.
Lung Neoplasms
MMP-2 and MMP-13 affect vasculogenic mimicry formation in large cell lung cancer.
Lung Neoplasms
MMP-2 siRNA induced Fas/CD95-mediated extrinsic II apoptotic pathway in the A549 lung adenocarcinoma cell line.
Lung Neoplasms
Modulation of MMP-2 and MMP-9 by cytokines, mitogens and inhibitors in lung cancer and malignant mesothelioma cell lines.
Lung Neoplasms
Modulatory effect of hesperidin on benzo(a)pyrene induced experimental lung carcinogenesis with reference to COX-2, MMP-2 and MMP-9.
Lung Neoplasms
N-myc downstream regulated gene 2 overexpression reduces matrix metalloproteinase-2 and -9 activities and cell invasion of A549 lung cancer cell line in vitro.
Lung Neoplasms
Naringenin inhibited migration and invasion of glioblastoma cells through multiple mechanisms.
Lung Neoplasms
Naringenin inhibits migration of lung cancer cells via the inhibition of matrix metalloproteinases-2 and -9.
Lung Neoplasms
Non-steroidal anti-inflammatory drugs inhibit matrix metalloproteinase-2 expression via repression of transcription in lung cancer cells.
Lung Neoplasms
Nonsteroidal anti-inflammatory drugs inhibit matrix metalloproteinase-2 via suppression of the ERK/Sp1-mediated transcription.
Lung Neoplasms
Osthole suppresses migration and invasion of A549 human lung cancer cells through inhibition of matrix metalloproteinase-2 and matrix metallopeptidase-9 in vitro.
Lung Neoplasms
Overexpression level of stromelysin 3 is related to the lymph node involvement in non-small cell lung cancer.
Lung Neoplasms
Overexpression of matrix metalloproteinase 2 predicts unfavorable outcome in early-stage non-small cell lung cancer.
Lung Neoplasms
Overexpression of matrix metalloproteinase-7 and -9 in NSCLC tumor and stromal cells: Correlation with a favorable clinical outcome.
Lung Neoplasms
Pipoxolan inhibits CL1-5 lung cancer cells migration and invasion through inhibition of MMP-9 and MMP-2.
Lung Neoplasms
Plasminogen Activator Inhibitor-2 Plays a Leading Prognostic Role among Protease Families in Non-Small Cell Lung Cancer.
Lung Neoplasms
Plumbagin inhibits TPA-induced MMP-2 and u-PA expressions by reducing binding activities of NF-kappaB and AP-1 via ERK signaling pathway in A549 human lung cancer cells.
Lung Neoplasms
Polymorphisms of matrix metalloproteinases 1, 2, 3 and 9 and susceptibility to lung, breast and colorectal cancer in over 30,000 subjects.
Lung Neoplasms
Prognosis of metastasis based on age and serum analytes after follow-up of non-metastatic lung cancer patients.
Lung Neoplasms
Prognostic impact of MMP-2 and MMP-9 expression in pathologic stage IA non-small cell lung cancer.
Lung Neoplasms
Prognostic significance of overexpressed matrix metalloproteinase-2, mouse-double minute: 2 homolog and epidermal growth factor receptor in non-small cell lung cancer.
Lung Neoplasms
Prognostic value of tissue inhibitor of metalloproteinase-2 expression in patients with non-small cell lung cancer: a systematic review and meta-analysis.
Lung Neoplasms
Progression of non-small cell lung cancer: diagnostic and prognostic utility of matrix metalloproteinase-2, C-reactive protein and serum amyloid A.
Lung Neoplasms
Quantitative Assessment of the Effects of MMP-2 Polymorphisms on Lung Carcinoma Risk.
Lung Neoplasms
Quercetin metabolites inhibit MMP-2 expression in A549 lung cancer cells by PPAR-? associated mechanisms.
Lung Neoplasms
Reduction of in vivo tumor growth by MMI-166, a selective matrix metalloproteinase inhibitor, through inhibition of tumor angiogenesis in squamous cell carcinoma cell lines of head and neck.
Lung Neoplasms
Relationship between matrix metalloproteinase 2 and lung cancer progression.
Lung Neoplasms
Resveratrol inhibits human lung adenocarcinoma cell metastasis by suppressing heme oxygenase 1-mediated nuclear factor-kappaB pathway and subsequently downregulating expression of matrix metalloproteinases.
Lung Neoplasms
Rho Guanine Nucleotide Exchange Factor 5 Increases Lung Cancer Cell Tumorigenesis via MMP-2 and Cyclin D1 Upregulation.
Lung Neoplasms
Salinomycin suppresses TGF-?1-induced EMT by down-regulating MMP-2 and MMP-9 via the AMPK/SIRT1 pathway in non-small cell lung cancer.
Lung Neoplasms
Serum metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in lung carcinoma patients.
Lung Neoplasms
Silibinin inhibits the invasion of human lung cancer cells via decreased productions of urokinase-plasminogen activator and matrix metalloproteinase-2.
Lung Neoplasms
Skp2 overexpression increases the expression of MMP-2 and MMP-9 and invasion of lung cancer cells.
Lung Neoplasms
Social defeat stress promotes tumor growth and angiogenesis by upregulating vascular endothelial growth factor/extracellular signal-regulated kinase/matrix metalloproteinase signaling in a mouse model of lung carcinoma.
Lung Neoplasms
Steroidal Saponins from Paris polyphylla Suppress Adhesion, Migration and Invasion of Human Lung Cancer A549 Cells Via Down-Regulating MMP-2 and MMP-9.
Lung Neoplasms
Study on the expression of p53 and MMP-2 in patients with lung cancer after interventional therapy.
Lung Neoplasms
Suppression of cell invasion and migration by propofol are involved in down-regulating matrix metalloproteinase-2 and p38 MAPK signaling in A549 human lung adenocarcinoma epithelial cells.
Lung Neoplasms
Targeting matrix metalloproteinases with novel diazepine substituted cinnamic acid derivatives: design, synthesis, in vitro and in silico studies.
Lung Neoplasms
The association of MMP-9 enzyme activity, MMP-9 C1562T polymorphism, and MMP-2 and -9 and TIMP-1, -2, -3, and -4 gene expression in lung cancer.
Lung Neoplasms
The Butanol Fraction of Guava (Psidium cattleianum Sabine) Leaf Extract Suppresses MMP-2 and MMP-9 Expression and Activity Through the Suppression of the ERK1/2 MAPK Signaling Pathway.
Lung Neoplasms
The impact of a chlorotoxin-modified liposome system on receptor MMP-2 and the receptor-associated protein ClC-3.
Lung Neoplasms
The Role of Matrix Metalloproteinase 2 on the Survival of Patients with Non-Small Cell Lung Cancer: A Systematic Review with Meta-Analysis.
Lung Neoplasms
The VEGFR2, COX-2 and MMP-2 polymorphisms are associated with clinical outcome of patients with inoperable non-small cell lung cancer.
Lung Neoplasms
Thymoquinone inhibits proliferation and invasion of human nonsmall-cell lung cancer cells via ERK pathway.
Lung Neoplasms
Timosaponin AIII inhibits migration and invasion of A549 human non-small-cell lung cancer cells via attenuations of MMP-2 and MMP-9 by inhibitions of ERK1/2, Src/FAK and ?-catenin signaling pathways.
Lung Neoplasms
Tissue inhibitor of metalloproteinase 3 suppresses tumor angiogenesis in matrix metalloproteinase 2-down-regulated lung cancer.
Lung Neoplasms
Tissue MMP-2 and MMP-9 [corrected] are better prognostic factors than serum MMP-2/TIMP-2--complex or TIMP-1 [corrected] in stage [corrected] I-III lung carcinoma.
Lung Neoplasms
Transfection of nm23-H1 increased expression of beta-Catenin, E-Cadherin and TIMP-1 and decreased the expression of MMP-2, CD44v6 and VEGF and inhibited the metastatic potential of human non-small cell lung cancer cell line L9981.
Lung Neoplasms
Tumor-associated macrophages provide a suitable microenvironment for non-small lung cancer invasion and progression.
Lung Neoplasms
Type IV collagenase/gelatinase (MMP-2) is not increased in plasma of patients with cancer.
Lung Neoplasms
Upregulation of MMP-2 by HMGA1 promotes transformation in undifferentiated, large-cell lung cancer.
Lung Neoplasms
[Dynamic study on expression of gelatinase A and its natural inhibitor during invasion and metastasis of induced lung cancer in Wistar rats]
Lung Neoplasms
[Effect of cyclooxygenase-2,and matrix metalloproteinase-2 expression on prognosis of lung cancer]
Lung Neoplasms
[Effect of hypoxia on infiltration and migration of lung cancer cells and expression of MMP-2 and TIMP-2.]
Lung Neoplasms
[Effect of Src tyrosine kinase inhibition on secretion of MMP-2 and MMP-9 by non-small cell lung cancer cells].
Lung Neoplasms
[Expression and pathological mechanism of MMP-9 and HIF-2? in CD133(+) lung cancer stem cells].
Lung Neoplasms
[Expression and significance of matrix metalloproteinases and their tissue inhibitors in the infiltration and metastasis of lung cancer.]
Lung Neoplasms
[Expression of bone morphogenetic proteins, matrix metalloproteinases and inhibitors of matrix metalloproteinases in lung cancers and their prognostic significance]
Lung Neoplasms
[Expression of membrane-type matrix metalloproteinase (MT-MMP) and activation of MMP-2 in lung cancer]
Lung Neoplasms
[Expression of MMP-2 and MMP-9 in non-small-cell lung cancer and their prognostic value.]
Lung Neoplasms
[New direct assay method of type IV collagenase in tissue homogenate and biochemical role of collagenase against type I, and IV collagens to the invasion of the stomach and lung cancer]
Lung Neoplasms
[Preliminary study of dihydroartemisin in inhibiting invasion and metastasis of hepatoma cells].
Lung Neoplasms
[Prognostic impact of matrix metalloproteinases 2,9, and 11 in stromal cells stage I non-small cell lung cancer]
Lung Neoplasms
[Promotion of MAG-1 on Metastasis of Lung Cancer Cells in vitro and Its Expression in Lung Cancer Tissue of 24 Cases.]
Lung Neoplasms
[Significance of caveolin-1 protein detected by quantum dots technique in human lung cancer invasiveness and metastasis.]
Lung Neoplasms
[The expression and its clinical significance of MMP-2 and MMP-9 in non-small cell lung cancer.]
Lupus Erythematosus, Cutaneous
Matrix metalloproteinase-2 and -9 activity levels increase in cutaneous lupus erythematosus lesions and correlate with disease severity.
Lupus Erythematosus, Systemic
Elevated circulatory MMP-2 and MMP-9 levels and activities in patients with rheumatoid arthritis and systemic lupus erythematosus.
Lupus Erythematosus, Systemic
Elevated serum levels of MMP-2, MMP-3, and MMP-13 in Chinese patients with systemic lupus erythematosus.
Lupus Erythematosus, Systemic
Expression of the matrix metalloproteinases MMP-2 and MMP-9 and their inhibitors TIMP-1 and TIMP-2 in systemic lupus erythematosus patients.
Lupus Erythematosus, Systemic
Matrix metalloproteinase-2 functional promoter polymorphism G1575A is associated with elevated circulatory MMP-2 level and increased risk of cardiovascular disease in systemic lupus erythematosus patients.
Lupus Erythematosus, Systemic
Neutrophil extracellular traps induce endothelial dysfunction in systemic lupus erythematosus through the activation of matrix metalloproteinase-2.
Lupus Erythematosus, Systemic
Role of MMP-2 and its inhibitor TIMP-2 as biomarkers for susceptibility to systemic lupus erythematosus.
Lupus Nephritis
Glomerular expression of matrix metalloproteinases in systemic lupus erythematosus in association with activity index and renal function.
Lupus Nephritis
Relationships between MMP-2, MMP-9, TIMP-1 and TIMP-2 levels and their pathogenesis in patients with lupus nephritis.
Lupus Nephritis
Significance of MMP-2 and TIMP-2 mRNA expressions on glomerular cells in the development of glomerulosclerosis.
Lyme Disease
Cloning of a salivary gland metalloprotease and characterization of gelatinase and fibrin(ogen)lytic activities in the saliva of the Lyme disease tick vector Ixodes scapularis.
Lymphadenopathy
Ratio of metalloproteinase 2 to tissue inhibitor of metalloproteinase 2 in medullary thyroid carcinoma.
Lymphangioleiomyomatosis
Doxycycline inhibits matrix metalloproteinase-2 secretion from TSC2-null mouse embryonic fibroblasts and lymphangioleiomyomatosis cells.
Lymphangioleiomyomatosis
Doxycycline use in patients with lymphangioleiomyomatosis: safety and efficacy in metalloproteinase blockade.
Lymphangioleiomyomatosis
Immunohistochemical study of matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) in pulmonary lymphangioleiomyomatosis (LAM).
Lymphatic Metastasis
Activation of MMP-2 and MMP-9 in patients with oral squamous cell carcinoma.
Lymphatic Metastasis
Activation of the precursor of gelatinase A/72 kDa type IV collagenase/MMP-2 in lung carcinomas correlates with the expression of membrane-type matrix metalloproteinase (MT-MMP) and with lymph node metastasis.
Lymphatic Metastasis
Active and inactive forms of matrix metalloproteinases 2 and 9 in cutaneous melanoma.
Lymphatic Metastasis
Altered expression of metastasis-associated and regulatory molecules in effusions from breast cancer patients: a novel model for tumor progression.
Lymphatic Metastasis
Association of single nucleotide polymorphisms of ?2-adrenergic receptor gene with clinicopathological features of pancreatic carcinoma.
Lymphatic Metastasis
Chromodomain Helicase/ATPase DNA-Binding Protein 1-Like Gene (CHD1L) Expression and Implications for Invasion and Metastasis of Breast Cancer.
Lymphatic Metastasis
Clinical significance of expression of membrane type 1 matrix metalloproteinase and matrix metalloproteinase-2 in human head and neck squamous cell carcinoma.
Lymphatic Metastasis
Clinical significance of matrix metalloproteinase 2 and 9 in breast cancer.
Lymphatic Metastasis
Clinical significance of matrix metalloproteinase-2 in cancer of uterine cervix: a semiquantitative study of immunoreactivities using tissue array.
Lymphatic Metastasis
Clinical significance of matrix metalloproteinase-2 in endometrial cancer: A systematic review and meta-analysis.
Lymphatic Metastasis
Clinicopathologic evaluation of immunohistochemical CD147 and MMP-2 expression in differentiated thyroid carcinoma.
Lymphatic Metastasis
Clinicopathological significance of E-cadherin, VEGF, and MMPs in gastric cancer.
Lymphatic Metastasis
Clinicopathological significance of matrix metalloproteinase 2 protein expression in patients with renal cell carcinoma: A case-control study and meta-analysis.
Lymphatic Metastasis
Clinicopathological Significance of Matrix Metalloproteinase-2 Protein Expression in Renal Cell Carcinoma Patients.
Lymphatic Metastasis
Correlation between expression of extracellular matrix metalloproteinase inducer and matrix metalloproteinase-2 and cervical lymph node metastasis of nasopharyngeal carcinoma.
Lymphatic Metastasis
Correlation of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinase expression in ileal carcinoids, lymph nodes and liver metastasis with prognosis and survival.
Lymphatic Metastasis
Correlations of serum VEGF and MMP-2 levels with CLM in CRC patients and effects of TACE on their expressions.
Lymphatic Metastasis
Differentially expressed genes between primary cancer and paired lymph node metastases predict clinical outcome of node-positive breast cancer patients.
Lymphatic Metastasis
Endometrial tumor invasiveness is related to metalloproteinase 2 and tissue inhibitor of metalloproteinase 2 expressions.
Lymphatic Metastasis
Enhanced production and activation of progelatinase A mediated by membrane-type 1 matrix metalloproteinase in human oral squamous cell carcinomas: implications for lymph node metastasis.
Lymphatic Metastasis
Enhanced production of matrix metalloproteinase-2 in human head and neck carcinomas is correlated with lymph node metastasis.
Lymphatic Metastasis
Evidence for increased activated metalloproteinase 2 (MMP-2a) expression associated with human prostate cancer progression.
Lymphatic Metastasis
Expression and clinical significance of matrix metalloproteinase-2 and matrix metalloproteinase-9 in oral squamous cell carcinoma.
Lymphatic Metastasis
Expression of cyclooxygenase-2, vascular endothelial growth factor and matrix metalloproteinase-2 in patients with primary laryngeal carcinoma: a tissue microarray study.
Lymphatic Metastasis
Expression of cytokeratin 19 and matrix metalloproteinase 2 predicts lymph node metastasis in hepatocellular carcinoma.
Lymphatic Metastasis
Expression of integrin alphaVbeta3 in pancreatic carcinoma: relation to MMP-2 activation and lymph node metastasis.
Lymphatic Metastasis
Expression of matrix metalloproteinase-2 and its tissue inhibitor-2 in fetal and neoplastic thyroid tissue and their significance as diagnostic and prognostic markers in papillary carcinoma.
Lymphatic Metastasis
Expression of matrix metalloproteinase-2 related to lymph node metastasis of oral squamous cell carcinoma. A clinicopathologic study.
Lymphatic Metastasis
Expression of matrix metalloproteinases in supraglottic carcinoma and its clinical implication for estimating lymph node metastases.
Lymphatic Metastasis
Expression of MMP-2 and TIMP-3 with incidence and prognosis of giant-cell tumor of the bone.
Lymphatic Metastasis
Expression of MMP-2 is associated with progression and lymph node metastasis of gastric carcinoma.
Lymphatic Metastasis
Expression of SHP2 and Related Markers in Non-Small Cell Lung Cancer: A Tissue Microarray Study of 80 Cases.
Lymphatic Metastasis
Expression of tissue levels of matrix metalloproteinases and their inhibitors in breast cancer.
Lymphatic Metastasis
Expression of tissue levels of matrix metalloproteinases and tissue inhibitors of metalloproteinases in gastric adenocarcinoma.
Lymphatic Metastasis
Expression of TRAP1 in gastric cancer tissue and its correlation with malignant biology.
Lymphatic Metastasis
Expressions of CD147, MMP-2 and MMP-9 in Laryngeal Carcinoma and its Correlation with Poor Prognosis.
Lymphatic Metastasis
Expressions of MMP-2, MMP-9 and VEGF are closely linked to growth, invasion, metastasis and angiogenesis of gastric carcinoma.
Lymphatic Metastasis
Extracellular matrix expression in metastasizing and nonmetastasizing adenocarcinomas of the lung.
Lymphatic Metastasis
GABRA3 promotes lymphatic metastasis in lung adenocarcinoma by mediating upregulation of matrix metalloproteinases.
Lymphatic Metastasis
Gelatinolytic activity of matrix metalloproteinase-2 and -9 in oesophageal carcinoma; a study using in situ zymography.
Lymphatic Metastasis
Gene Expression Profiling of Fixed Tissues Identified Hypoxia-Inducible Factor-1{alpha}, VEGF, and Matrix Metalloproteinase-2 as Biomarkers of Lymph Node Metastasis in Hepatocellular Carcinoma.
Lymphatic Metastasis
HAND2-AS1 inhibits invasion and metastasis of cervical cancer cells via microRNA-330-5p-mediated LDOC1.
Lymphatic Metastasis
High expression of osteoglycin decreases gelatinase activity of murine hepatocarcinoma Hca-F cells.
Lymphatic Metastasis
High MMP-21 expression in metastatic lymph nodes predicts unfavorable overall survival for oral squamous cell carcinoma patients with lymphatic metastasis.
Lymphatic Metastasis
HMGA2 gene silencing reduces epithelial-mesenchymal transition and lymph node metastasis in cervical cancer through inhibiting the ATR/Chk1 signaling pathway.
Lymphatic Metastasis
Immunoexpression of matrix metalloproteinase-2 (MMP-2) in malignant ovarian epithelial tumours.
Lymphatic Metastasis
Immunohistochemical distribution of type IV collagenase in normal, dysplastic and neoplastic canine mammary gland.
Lymphatic Metastasis
Immunohistochemical evaluation of MMP-2, MMP-9 and CD31/microvascular density in squamous cell carcinomas of the floor of the mouth.
Lymphatic Metastasis
Immunohistochemical levels of matrix metalloproteinase-2 and CD44 variant 6 protein in the diagnosis and lateral cervical lymph node metastasis of papillary thyroid carcinoma.
Lymphatic Metastasis
Increased expression and activation of gelatinolytic matrix metalloproteinases is associated with the progression and recurrence of human cervical cancer.
Lymphatic Metastasis
Increased expression and activation of matrix metalloproteinase-2 (MMP-2) in O-1N: hamster oral squamous cell carcinoma with high potential lymph node metastasis.
Lymphatic Metastasis
Increased plasma MMP-2 protein expression in lymph node-positive patients with colorectal cancer.
Lymphatic Metastasis
Inhibition of cervical lymph node metastasis by marimastat (BB-2516) in an orthotopic oral squamous cell carcinoma implantation model.
Lymphatic Metastasis
Intratumoral heterogeneity and inverse correlation between expression of E-cadherin and collagenase type IV in human gastric carcinomas.
Lymphatic Metastasis
Intratumoral macrophage counts correlate with tumor progression in colorectal cancer.
Lymphatic Metastasis
Involvement of matrix metalloproteinase-2 activity in invasion and metastasis of pancreatic carcinoma.
Lymphatic Metastasis
LABAZ1: A metastatic tumor model for renal cell carcinoma expressing the carbonic anhydrase type 9 tumor antigen.
Lymphatic Metastasis
Low expression of RECK in oral squamous cell carcinoma patients induces a shorter survival rate through an imbalance of RECK/MMPs.
Lymphatic Metastasis
Lymph Node Metastasis of Gastric Cancer Is Associated with the Interaction Between Poly (ADP-Ribose) Polymerase 1 and Matrix Metallopeptidase 2.
Lymphatic Metastasis
Lymph node micrometastasis and its correlation with MMP-2 expression in gastric carcinoma.
Lymphatic Metastasis
Matrix metalloproteinase 2 immunoreactive protein appears early in cervical epithelial dedifferentiation.
Lymphatic Metastasis
Matrix metalloproteinase-2 and tissue inhibitor of metallo-proteinase-2 in colorectal carcinoma invasion and metastasis.
Lymphatic Metastasis
Matrix metalloproteinase-2 expression in laryngeal preneoplastic and neoplastic lesions.
Lymphatic Metastasis
Matrix metalloproteinase-2 expression in stromal tissues is a consistent prognostic factor in stage II colon cancer.
Lymphatic Metastasis
Matrix metalloproteinases 2 and 9 in situ mRNA expression in colorectal tumors from Iraqi patients.
Lymphatic Metastasis
Metalloproteinases and their inhibitors: Influence on tumor invasiveness and metastasis formation in head and neck squamous cell carcinomas.
Lymphatic Metastasis
MMP-2 together with MMP-9 overexpression correlated with lymph node metastasis and poor prognosis in early gastric carcinoma.
Lymphatic Metastasis
Overexpression of MMP-2 and MMP-9 in esophageal squamous cell carcinoma.
Lymphatic Metastasis
Pancreatic Stellate Cells Activation and Matrix Metallopeptidase 2 Expression Correlate With Lymph Node Metastasis in Pancreatic Carcinoma.
Lymphatic Metastasis
Pathological and prognostic significance of matrix metalloproteinase-2 expression in ovarian cancer: a meta-analysis.
Lymphatic Metastasis
Pituitary tumor-transforming 1 expression in laryngeal cancer and its association with prognosis.
Lymphatic Metastasis
Plasma gelatinase levels in patients with primary breast cancer in relation to axillary lymph node status, Her2/neu expression and other clinicopathological variables.
Lymphatic Metastasis
Production of matrix metalloproteinase-2 and metalloproteinase-3 related to malignant behavior of esophageal carcinoma. A clinicopathologic study.
Lymphatic Metastasis
Prognostic significance of circulating matrix metalloproteinase-2 to tissue inhibitor of metalloproteinases-2 ratio in recurrence of urothelial cancer after complete resection.
Lymphatic Metastasis
Prognostic significance of phosphorylated signal transducer and activator of transcription 3 and suppressor of cytokine signaling 3 expression in human cutaneous melanoma.
Lymphatic Metastasis
Prognostic value of membrane type 1 and 2 matrix metalloproteinase expression and gelatinase A activity in bladder cancer.
Lymphatic Metastasis
Ratio of metalloproteinase 2 to tissue inhibitor of metalloproteinase 2 in medullary thyroid carcinoma.
Lymphatic Metastasis
Relationship between matrix metalloproteinase-2 mRNA expression and clinicopathological and urokinase-type plasminogen activator system parameters and prognosis in human gastric cancer.
Lymphatic Metastasis
Relationship between protein expression of VEGF-C, MMP-2 and lymph node metastasis in papillary thyroid cancer.
Lymphatic Metastasis
Serum MMP-2 as a potential predictive marker for papillary thyroid carcinoma.
Lymphatic Metastasis
Silencing of LASS2/TMSG1 enhances invasion and metastasis capacity of prostate cancer cell.
Lymphatic Metastasis
The collagenase activities, interstitial collagenase and type IV collagenase, in human stomach cancer: with special reference to local spreading and lymph node metastasis.
Lymphatic Metastasis
The expression and clinical significance of metastasis suppressor gene and matrix metalloproteinase-2 in esophageal squamous cell of carcinoma.
Lymphatic Metastasis
The expression and significance of AKR1B10 in laryngeal squamous cell carcinoma.
Lymphatic Metastasis
The Immunohistochemical Expression of STAT3, Bcl-xL, and MMP-2 Proteins in Colon Adenoma and Adenocarcinoma.
Lymphatic Metastasis
The impact of matrix metalloproteinase 2 on prognosis and clinicopathology of breast cancer patients: a systematic meta-analysis.
Lymphatic Metastasis
The relationship between MMP-2 and MMP-9 expression levels with breast cancer incidence and prognosis.
Lymphatic Metastasis
Tumor progression driven by pathways activating matrix metalloproteinases and their inhibitors.
Lymphatic Metastasis
Type IV collagenase and immunostaining of type IV collagen in human thyroid tumors.
Lymphatic Metastasis
Upregulated EMMPRIN/CD147 might contribute to growth and angiogenesis of gastric carcinoma: a good marker for local invasion and prognosis.
Lymphatic Metastasis
Upregulated matrix metalloproteinase-2 and downregulated tissue factor pathway inhibitor-2 are risk factors for lymph node metastasis and perineural invasion in pancreatic carcinoma.
Lymphatic Metastasis
Vascular endothelial growth factor-C expression and invasive phenotype in ovarian carcinomas.
Lymphatic Metastasis
VEGF-D-enhanced lymph node metastasis of ovarian cancer is reversed by vesicular stomatitis virus matrix protein.
Lymphatic Metastasis
[Association of JMJD3, MMP-2 and VEGF expressions with clinicopathological features of invasive ductal breast carcinoma].
Lymphatic Metastasis
[Correlation between expression of matrix metalloproteinase-2 and angiogenesis in esophageal carcinoma]
Lymphatic Metastasis
[Correlation between expression of metastasis-related genes and lymph node metastasis in testicular cancer]
Lymphatic Metastasis
[Correlations of serous levels of matrix metalloproteinases (MMP-2 and MMP-9) to invasion and metastasis of papillary thyroid carcinoma]
Lymphatic Metastasis
[Expression and clinical significance of MMP-2, MMP-9,TIMP-1, and TIMP-2 in breast carcinoma]
Lymphatic Metastasis
[Expression of FOXC-2 and YB-1 in Gastric Carcinoma and Its Role in Invasion and Metastasis].
Lymphatic Metastasis
[Expression of LOX and MMP-2 in gastric cancer tissue and the effects of LOX and MMP-2 on tumor invasion and metastasis].
Lymphatic Metastasis
[Expression of matrix metalloproteinase-2 in hypopharyngeal carcinoma and its clinical significance]
Lymphatic Metastasis
[Expression of matrix metalloproteinase-2, 9 and their inhibitor-TIMP 1,2 in human squamous cell carcinoma of uterine cervix]
Lymphatic Metastasis
[Expression of matrix metalloproteinase-2,9 in hypopharyngeal carcinoma and its relationship with lymphatic metastasis]
Lymphatic Metastasis
[Expression of matrix metaloproteinase and tissue inhibitors in ovarian tumors]
Lymphatic Metastasis
[Expression of membrane-type matrix metalloproteinase (MT-MMP) and activation of MMP-2 in lung cancer]
Lymphatic Metastasis
[Expression of MMP-2 and E-CD in salivary mucoepidermoid carcinoma and its correlation with infiltration, metastasis and prognosis]
Lymphatic Metastasis
[Expression of MMP-2 and its clinical significance in cervical squamous carcinoma]
Lymphatic Metastasis
[Expression of MMP-2, MMP-9, TIMP-1 and their relationship with prognosis in NSCLC.]
Lymphatic Metastasis
[Expressions of CD147 and matrix metalloproteinase-2 in breast cancer and their correlations to prognosis]
Lymphatic Metastasis
[Expressions of CD147, MMP-2 and MMP-9 in laryngeal carcinoma and clinical significance]
Lymphatic Metastasis
[Expressions of COX-2 and MMP-2 in nasopharyngeal carcinoma and the their relationship with lymph node metastasis]
Lymphatic Metastasis
[Expressions of vascular endothelial growth factor C and matrix metalloproteinases-2 and prognosis of non-small cell lung carcinoma.]
Lymphatic Metastasis
[Helicobacter pylori infection, the invasion and metastasis of the gastric carcinoma, and the expression of MMP-2 and TIMP-2]
Lymphatic Metastasis
[Relationship between expression of MMP-2 and prognosis in human laryngeal squamous cell carcinoma].
Lymphatic Metastasis
[Role of matrix metalloproteinase (MMP)-2 and -9 and vascular endothelial growth factor C in lymph node metastasis of breast cancer.]
Lymphatic Metastasis
[Study of type I and IV collagenase activity in human thyroid diseases]
Lymphatic Metastasis
[Study on expression of matrix metalloproteinases and their inhibitors in parotid gland tumors]
Lymphatic Metastasis
[The correlation between neck lymphy node metastasis and matrixmetalloproteinase-2 expression at the invasive tumor front of oral squamous cell carcinomas]
Lymphatic Metastasis
[The effects of MMPs and TIMPs on the metastasis of oral squamous cell carcinoma to neck lymph nodes]
Lymphatic Metastasis
[The expression and its clinical significance of MMP-2 and MMP-9 in non-small cell lung cancer.]
Lymphatic Metastasis
[The expression of matrix metalloproteinase-2 and -9 in cervical cancer and a study of their relationship]
Lymphatic Metastasis
[The expression of MMP-2, E-cadherin in supraglottic carcinoma and their relationship with cervical lymph nody metastasis]
Lymphatic Metastasis
[The relation between integrin, type IV collagenase and extracellular matrix in invasion and metastasis of gastric carcinoma]
Lymphocele
Doxycycline sclerotherapy of lymphocele after renal transplantation and its inhibition of gelatinase activity.
Lymphoma
CircHIPK2 Contributes to DDP Resistance and Malignant Behaviors of DDP-Resistant Ovarian Cancer Cells Both in vitro and in vivo Through circHIPK2/miR-338-3p/CHTOP ceRNA Pathway.
Lymphoma
Distinct Functionality of Tumor Cell-Derived Gelatinases during Formation of Liver Metastases.
Lymphoma
Emmprin, a cell surface inducer of matrix metalloproteinases (MMPs), is expressed in T-cell lymphomas.
Lymphoma
Expression of the metalloproteases MMP-1, MMP-2, MMP-3, MMP-9, MMP-11, TIMP-1 and TIMP-2 in angiocentric midfacial lymphomas.
Lymphoma
Gelatinases (MMP-2 and MMP-9), TIMP-1 expression and the extent of neovascularization in aggressive non-Hodgkin's lymphomas.
Lymphoma
Interleukin-6 regulation of matrix metalloproteinase (MMP-2 and MMP-9) and tissue inhibitor of metalloproteinase (TIMP-1) expression in malignant non-Hodgkin's lymphomas.
Lymphoma
Lack of prognostic value of MMP-9 expression and immunohistochemically defined germinal center phenotype in patients with diffuse large B-cell lymphoma treated with modern chemotherapy with or without CD20 antibody.
Lymphoma
Matrix metalloproteinase-9 and vascular endothelial growth factor: a possible link in adult T-cell leukaemia cell invasion.
Lymphoma
Molecular mechanisms behind the biological effects of hesperidin and hesperetin for the prevention of cancer and cardiovascular diseases.
Lymphoma
The cloning and expression of matrix metalloproteinase-2 and tissue inhibitor of matrix metalloproteinase 2 in normal canine lymph nodes and in canine lymphoma.
Lymphoma, B-Cell
Berberine hydrochloride inhibits cell proliferation and promotes apoptosis of non-small cell lung cancer via the suppression of the MMP2 and Bcl-2/Bax signaling pathways.
Lymphoma, B-Cell
CircHIPK2 Contributes to DDP Resistance and Malignant Behaviors of DDP-Resistant Ovarian Cancer Cells Both in vitro and in vivo Through circHIPK2/miR-338-3p/CHTOP ceRNA Pathway.
Lymphoma, B-Cell
circRPS28 (hsa_circ_0049055) is a novel contributor for papillary thyroid carcinoma by regulating cell growth and motility via functioning as ceRNA for miR-345-5p to regulate frizzled family receptor 8 (FZD8).
Lymphoma, B-Cell
Combination Efficacy of Astragalus membranaceus and Curcuma wenyujin at Different Stages of Tumor Progression in an Imageable Orthotopic Nude Mouse Model of Metastatic Human Ovarian Cancer Expressing Red Fluorescent Protein.
Lymphoma, B-Cell
Hepatitis C virus activates Bcl-2 and MMP-2 expression through multiple cellular signaling pathways.
Lymphoma, B-Cell
Knockdown of REG? inhibits the proliferation and migration and promotes the apoptosis of multiple myeloma cells by downregulating NF-?B signal pathway.
Lymphoma, B-Cell
microRNA-613 exerts anti-angiogenic effect on nasopharyngeal carcinoma cells through inactivating the AKT signaling pathway by down-regulating FN1.
Lymphoma, B-Cell
Protective effect of genistein isolated from Hydrocotyle sibthorpioides on hepatic injury and fibrosis induced by chronic alcohol in rats.
Lymphoma, B-Cell
Sanguinarine inhibits growth and invasion of gastric cancer cells via regulation of the DUSP4/ERK pathway.
Lymphoma, B-Cell
Upregulation of ARHGAP30 attenuates pancreatic cancer progression by inactivating the ?-catenin pathway.
Lymphoma, Follicular
Prognostic significance of p53 and matrix metalloproteinase-9 expression in follicular lymphoma.
Lymphoma, Non-Hodgkin
Association between matrix metalloproteinase 2 (MMP2) promoter polymorphisms and the susceptibility to non-Hodgkin's lymphoma in Egyptians.
Lymphoma, Non-Hodgkin
Human neutrophil gelatinase: a marker for circulating blood neutrophils. Purification and quantitation by enzyme linked immunosorbent assay.
Lymphoma, Non-Hodgkin
Large B-cell lymphoma of the leg--complete remission with perilesional interferon alpha.
Lymphoma, Non-Hodgkin
Matrix metalloproteinase-2 promoter and tissue inhibitor of metalloproteinase-2 gene polymorphisms in non-Hodgkin's lymphoma.
Lymphoma, Non-Hodgkin
Matrix Metalloproteinase-2 Single Nucleotide Polymorphism in Egyptian Non-Hodgkin Lymphoma Patients: Correlation with Clinicopathological Characteristics and Outcome.
Lymphoma, Non-Hodgkin
Plasma MMP-2-TIMP-2 complex levels measured during follow-up predict a risk of relapse in patients with malignant lymphoma.
Lymphoma, Non-Hodgkin
Prognostic value of matrix metalloproteinases (MMP-2 and MMP-9) in Hodgkin's and non-Hodgkin's lymphoma.
Lymphoma, Non-Hodgkin
Role of gelatinases (MMP-2 and MMP-9), TIMP-1, vascular endothelial growth factor (VEGF), and microvessel density on the clinicopathological behavior of childhood non-Hodgkin lymphoma.
Lymphoma, T-Cell
miRNA-218 inhibits osteosarcoma cell migration and invasion by down-regulating of TIAM1, MMP2 and MMP9.
Lymphoma, T-Cell, Cutaneous
Matrix metalloproteinase-2 promoter genotype as a marker of cutaneous T-cell lymphoma early stage.
Lymphopenia
Recombinant mouse granulocyte chemotactic protein-2: production in bacteria, characterization, and systemic effects on leukocytes.
Macular Degeneration
Age-dependent variation in metalloproteinase activity of isolated human Bruch's membrane and choroid.
Macular Degeneration
Angiotensin II-induced MMP-2 activity and MMP-14 and basigin protein expression are mediated via the angiotensin II receptor type 1-mitogen-activated protein kinase 1 pathway in retinal pigment epithelium implications for age-related macular degeneration.
Macular Degeneration
Association analysis of genetic polymorphisms and expression levels of selected genes involved in extracellular matrix turnover and angiogenesis with the risk of age-related macular degeneration.
Macular Degeneration
Estrogen receptor alpha and matrix metalloproteinase 2 polymorphisms and age-related maculopathy in older women.
Macular Degeneration
Increase in interphotoreceptor matrix gelatinase A (MMP-2) associated with age-related macular degeneration.
Macular Degeneration
Matrix metalloproteinase (MMP) expression in experimental choroidal neovascularization.
Macular Degeneration
Meta-analysis of the rs243865 MMP-2 polymorphism and age-related macular degeneration risk.
Macular Degeneration
MMP-2 Rs24386 (C-->T) gene polymorphism and the phenotype of age-related macular degeneration.
Macular Degeneration
Nonlethal oxidant injury to human retinal pigment epithelium cells causes cell membrane blebbing but decreased MMP-2 activity.
Macular Degeneration
Plasma levels of matrix metalloproteinase-2 and -9 (MMP-2 and MMP-9) in age-related macular degeneration.
Macular Degeneration
Reduced choroidal neovascular membrane formation in matrix metalloproteinase-2-deficient mice.
Macular Degeneration
Risk of macular degeneration affected by polymorphisms in Matrix metalloproteinase-2: A case-control study in Chinese Han population.
Macular Degeneration
Role of MMP-2 (-1306?C/T) Polymorphism in Age-Related Macular Degeneration.
Macular Degeneration
Serum levels of matrix metalloproteinase 2 and matrix metalloproteinase 9 elevated in polypoidal choroidal vasculopathy but not in age-related macular degeneration.
Macular Degeneration
The Role of Matrix Metalloproteinases Polymorphisms in Age-Related Macular Degeneration.
Macular Degeneration
The Role of MMP2 (-1306C>T) and TIMP2 (-418 G>C) Promoter Variants in Age-related Macular Degeneration.
Macular Degeneration
[Prevention and treatment of age-related macular degeneration by extract of Fructus lycii and its constituents lutein/zeaxanthin: an in vive and in vitro experimental research].
Macular Edema
The relationship between plasma MMP-9 and TIMP-2 levels and intraocular pressure elevation in diabetic patients after intravitreal triamcinolone injection.
Malnutrition
Long-term effects of maternal undernutrition on offspring carotid artery remodeling: role of miR-29c.
Marfan Syndrome
Immunohistochemistry of matrix metalloproteinases and their inhibitors in thoracic aortic aneurysms and aortic valves of patients with Marfan's syndrome.
Marfan Syndrome
Long-term doxycycline is more effective than atenolol to prevent thoracic aortic aneurysm in marfan syndrome through the inhibition of matrix metalloproteinase-2 and -9.
Marfan Syndrome
Loss of elastic fiber integrity and reduction of vascular smooth muscle contraction resulting from the upregulated activities of matrix metalloproteinase-2 and -9 in the thoracic aortic aneurysm in Marfan syndrome.
Marfan Syndrome
MMP-2 regulates Erk1/2 phosphorylation and aortic dilatation in Marfan syndrome.
Mastitis
Increase in milk metalloproteinase activity and vascular permeability in bovine endotoxin-induced and naturally occurring Escherichia coli mastitis.
Mastocytoma
Dog mast cell alpha-chymase activates progelatinase B by cleaving the Phe88-Gln89 and Phe91-Glu92 bonds of the catalytic domain.
Mastocytoma
Dog mastocytoma cells secrete a 92-kD gelatinase activated extracellularly by mast cell chymase.
Medulloblastoma
Expression of matrix metalloproteinases and their tissue inhibitors in human brain tumors.
Medulloblastoma
Matrix metalloproteinase expression in childhood medulloblastomas/primitive neuroectodermal tumors.
Medulloblastoma
MMP-2 mediates mesenchymal stem cell tropism towards medulloblastoma tumors.
Medulloblastoma
Significant differences in the matrix metalloproteinase expression profiles of spontaneous medulloblastomas/primitive neuroectodermal tumors as compared with their xenografted, established tumor cell line derived counterparts.
Melanoma
(-)-Oleocanthal exerts anti-melanoma activities and inhibits STAT3 signaling pathway.
Melanoma
2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) induces matrix metalloproteinase (MMP) expression and invasion in A2058 melanoma cells.
Melanoma
?-Elemene inhibits the metastasis of B16F10 melanoma cells by downregulation of the expression of uPA, uPAR, MMP-2, and MMP-9.
Melanoma
A 170-kDa membrane-bound protease is associated with the expression of invasiveness by human malignant melanoma cells.
Melanoma
A comparison of ocular melanocyte and uveal melanoma cell invasion and the implication of alpha1beta1, alpha4beta1 and alpha6beta1 integrins.
Melanoma
A new approach for the treatment of malignant melanoma: enhanced antitumor efficacy of an albumin-binding doxorubicin prodrug that is cleaved by matrix metalloproteinase 2.
Melanoma
A novel matrix metalloproteinase-2 inhibitor triazolylmethyl aziridine reduces melanoma cell invasion, angiogenesis and targets ERK1/2 phosphorylation.
Melanoma
A novel synthetic oleanane triterpenoid suppresses adhesion, migration, and invasion of highly metastatic melanoma cells by modulating gelatinase signaling axis.
Melanoma
A potential marker protease of invasiveness, seprase, is localized on invadopodia of human malignant melanoma cells.
Melanoma
A prognostic index in skin melanoma through the combination of matrix metalloproteinase-2, Ki67, and p53.
Melanoma
A specific sequence of the noncollagenous domain of the alpha3(IV) chain of type IV collagen inhibits expression and activation of matrix metalloproteinases by tumor cells.
Melanoma
Acetylsalicylic acid regulates MMP-2 activity and inhibits colorectal invasion of murine B16F0 melanoma cells in C57BL/6J mice: Effects of prostaglandin F(2)alpha.
Melanoma
Acidic extracellular pH promotes experimental metastasis of human melanoma cells in athymic nude mice.
Melanoma
ACTIBIND, a T2 RNase, competes with angiogenin and inhibits human melanoma growth, angiogenesis, and metastasis.
Melanoma
Activated leukocyte cell adhesion molecule (ALCAM/CD166/MEMD), a novel actor in invasive growth, controls matrix metalloproteinase activity.
Melanoma
Active and inactive forms of matrix metalloproteinases 2 and 9 in cutaneous melanoma.
Melanoma
alpha v beta3-dependent cross-presentation of matrix metalloproteinase-2 by melanoma cells gives rise to a new tumor antigen.
Melanoma
Alpha-V-dependent outside-in signaling is required for the regulation of CD44 surface expression, MMP-2 secretion, and cell migration by osteopontin in human melanoma cells.
Melanoma
Alterations in endothelial cell proteinase and inhibitor polarized secretion following treatment with interleukin-1, phorbol ester, and human melanoma cell conditioned medium.
Melanoma
An inhibitor of stress-activated MAP-kinases reduces invasion and MMP-2 expression of malignant melanoma cells.
Melanoma
Angiopoietin-like 4 promotes melanoma cell invasion and survival through aldolase A.
Melanoma
Anti-angiogenesis effect of essential oil from Curcuma zedoaria in vitro and in vivo.
Melanoma
Anti-metastatic Effects of Cationic KT2 Peptide (a Lysine/Tryptophan-rich Peptide) on Human Melanoma A375.S2 Cells.
Melanoma
Anti-tumor activities of chondroitinase AC and chondroitinase B: inhibition of angiogenesis, proliferation and invasion.
Melanoma
Antimetastatic potential of vernolide-A, a sesquiterpenoid from Vernonia cinerea L.
Melanoma
Antiproliferative and anti-invasive effects of inorganic and organic arsenic compounds on human and murine melanoma cells in vitro.
Melanoma
Antitumor efficacy of reticulol from Streptoverticillium against the lung metastasis model B16F10 melanoma. Lung metastasis inhibition by growth inhibition of melanoma.
Melanoma
AT1 receptors activation enhances the expression of MMP-2, MMP-13 and VEGF but not MMP-9 in B16F10 melanoma cells.
Melanoma
Attenuation of melanoma invasion by a secreted variant of activated leukocyte cell adhesion molecule.
Melanoma
Basal caspase-3 activity promotes migration, invasion, and vasculogenic mimicry formation of melanoma cells.
Melanoma
Basigin (CD147) is expressed on melanoma cells and induces tumor cell invasion by stimulating production of matrix metalloproteinases by fibroblasts.
Melanoma
Beneficial regulation of matrixmetalloproteinases and their inhibitors, fibrillar collagens and transforming growth factor-beta by Polypodium leucotomos, directly or in dermal fibroblasts, ultraviolet radiated fibroblasts, and melanoma cells.
Melanoma
Binding of alpha5 monoclonal antibody to cell surface alpha5beta1 integrin modulates MMP-2 and MMP-7 activity in B16F10 melanoma cells.
Melanoma
Black tea polyphenol (theaflavin) downregulates MMP-2 in human melanoma cell line A375 by involving multiple regulatory molecules.
Melanoma
Bornyl cis-4-Hydroxycinnamate Suppresses Cell Metastasis of Melanoma through FAK/PI3K/Akt/mTOR and MAPK Signaling Pathways and Inhibition of the Epithelial-to-Mesenchymal Transition.
Melanoma
Calcium influx modulates expression of matrix metalloproteinase-2 (72-kDa type IV collagenase, gelatinase A).
Melanoma
Cancer/Testis Antigens: Expression, Regulation, Tumor Invasion, and Use in Immunotherapy of Cancers.
Melanoma
Cantharidin Impairs Cell Migration and Invasion of A375.S2 Human Melanoma Cells by Suppressing MMP-2 and -9 Through PI3K/NF-?B Signaling Pathways.
Melanoma
Casticin Inhibits A375.S2 Human Melanoma Cell Migration/Invasion through Downregulating NF-?B and Matrix Metalloproteinase-2 and -1.
Melanoma
CD147 and matrix-metalloproteinase-2 expression in metastatic and non-metastatic uveal melanomas.
Melanoma
CD44-epidermal growth factor receptor interaction mediates hyaluronic acid-promoted cell motility by activating protein kinase C signaling involving Akt, Rac1, Phox, reactive oxygen species, focal adhesion kinase, and MMP-2.
Melanoma
Cell membrane-associated MT1-MMP-dependent activation of pro-MMP-2 in A375 melanoma cells.
Melanoma
Cell surface chondroitin sulfate glycosaminoglycan in melanoma: role in the activation of pro-MMP-2 (pro-gelatinase A).
Melanoma
Chemically modified tetracyclines inhibit human melanoma cell invasion and metastasis.
Melanoma
Clinical relevance of serum levels of matrix metallopeptidase-2, and tissue inhibitor of metalloproteinase-1 and -2 in patients with malignant melanoma.
Melanoma
Co-regulated expression of matrix metalloproteinase-2 and transforming growth factor-beta in melanoma development and progression.
Melanoma
Coexpression of integrin alpha(v)beta3 and matrix metalloproteinase-2 (MMP-2) coincides with MMP-2 activation: correlation with melanoma progression.
Melanoma
Comparison of the prognostic value of matrix metalloproteinases 2 and 9 in cutaneous melanoma.
Melanoma
Control of melanoma invasiveness by anticollagenolytic agents: a reappraisal of an old concept.
Melanoma
Cooperative interactions of laminin 5 gamma2 chain, matrix metalloproteinase-2, and membrane type-1-matrix/metalloproteinase are required for mimicry of embryonic vasculogenesis by aggressive melanoma.
Melanoma
Coordinate expression of membrane type-matrix metalloproteinases-2 and 3 (MT2-MMP and MT3-MMP) and matrix metalloproteinase-2 (MMP-2) in primary and metastatic melanoma cells.
Melanoma
Coordinated targeting of MMP-2/MMP-9 by miR-296-3p/FOXCUT exerts tumor-suppressing effects in choroidal malignant melanoma.
Melanoma
CSE1L, a novel microvesicle membrane protein, mediates Ras-triggered microvesicle generation and metastasis of tumor cells.
Melanoma
Culture of human A375 melanoma cells in the presence of fibronectin causes expression of MMP-9 and activation of MMP-2 in culture supernatants.
Melanoma
Cumulative influence of matrix metalloproteinase-1 and -2 in the migration of melanoma cells within three-dimensional type I collagen lattices.
Melanoma
Cytochalasin D disruption of actin filaments in 3T3 cells produces an anti-apoptotic response by activating gelatinase A extracellularly and initiating intracellular survival signals.
Melanoma
Cytochrome P450 17 (CYP17) Is Involved in Endometrial Cancinogenesis Through Apoptosis and Invasion Pathways.
Melanoma
Cytokine sensitivity of metastatic human melanoma cell lines-- simultaneous inhibition of proliferation and enhancement of gelatinase activity.
Melanoma
Cytotoxicity of the matrix metalloproteinase-activated anthrax lethal toxin is dependent on gelatinase expression and B-RAF status in human melanoma cells.
Melanoma
Danshensu has anti-tumor activity in B16F10 melanoma by inhibiting angiogenesis and tumor cell invasion.
Melanoma
De-N-acetyl GM3 promotes melanoma cell migration and invasion through urokinase plasminogen activator receptor signaling-dependent MMP-2 activation.
Melanoma
Decreased expression levels of cell cycle regulators and matrix metalloproteinases in melanoma from RET-transgenic mice by single irradiation of non-equilibrium atmospheric pressure plasmas.
Melanoma
Different levels of TGFbeta, IL-10, IFNgamma and gelatinase A occur in experimental white and black metastases induced by bryostatin 1 or by phorbol ester-treated BL6T murine melanoma cells.
Melanoma
Differential expression of matrix metalloproteinase-2 by fibroblasts in co-cultures with keratinocytes, basal cell carcinoma and melanoma.
Melanoma
Diversity of melanoma plasma membrane proteinases: inhibition of collagenolytic and cytolytic activities by minocycline.
Melanoma
Dominant-negative transcription factor AP-2 augments SB-2 melanoma tumor growth in vivo.
Melanoma
Down-regulating Myoferlin inhibits the vasculogenic mimicry of melanoma via decreasing MMP-2 and inducing mesenchymal-to-epithelial transition.
Melanoma
Downregulation of BRCA1 in A375 melanoma cell line increases radio-sensitivity and modifies metastatic and angiogenic gene expression.
Melanoma
Downregulation of matrix metalloproteinase-2 (MMP-2) utilizing adenovirus-mediated transfer of small interfering RNA (siRNA) in a novel spinal metastatic melanoma model.
Melanoma
Effect of tissue inhibitor of the matrix metalloproteinases-2 expression on the growth and spontaneous metastasis of a human melanoma cell line.
Melanoma
Eicosapentaenoic acid reduces the invasive and metastatic activities of malignant tumor cells.
Melanoma
eIF4E Is an Adverse Prognostic Marker of Melanoma Patient Survival by Increasing Melanoma Cell Invasion.
Melanoma
Elastin-derived peptides upregulate matrix metalloproteinase-2-mediated melanoma cell invasion through elastin-binding protein.
Melanoma
Epigallocatechingallate inhibits migration of human uveal melanoma cells via downregulation of matrix metalloproteinase-2 activity and ERK1/2 pathway.
Melanoma
Evaluation of EMMPRIN and MMP-2 in the prognosis of primary cutaneous malignant melanoma.
Melanoma
Expression and activation of matrix metalloproteinase-2 (MMP-2) and its co-localization with membrane-type 1 matrix metalloproteinase (MT1-MMP) correlate with melanoma progression.
Melanoma
Expression and activation of pro-gelatinase A by human melanoma cell lines with different tumorigenic potential.
Melanoma
Expression and role of matrix metalloproteinases MMP-2 and MMP-9 in human spinal column tumors.
Melanoma
Expression of collagenases-1 and -3 and their inhibitors TIMP-1 and -3 correlates with the level of invasion in malignant melanomas.
Melanoma
Expression of Id-1 is regulated by MCAM/MUC18: A missing link in melanoma progression.
Melanoma
Expression of integrin alpha(v)beta(3) correlates with activation of membrane-type matrix metalloproteinase-1 (MT1-MMP) and matrix metalloproteinase-2 (MMP-2) in human melanoma cells in vitro and in vivo.
Melanoma
Expression of interleukin-8 by human melanoma cells up-regulates MMP-2 activity and increases tumor growth and metastasis.
Melanoma
Expression of matrix metalloproteinase (MMP)-2, MMP-9, and tissue inhibitor of MMP (TIMP)-1 in conjunctival melanomas and clinical implications.
Melanoma
Expression of matrix metalloproteinase-2 and -9 and membrane-type 1 matrix metalloproteinase in melanocytic tumors of dogs and canine melanoma cell lines.
Melanoma
Expression of matrix metalloproteinases in the microenvironment of spontaneous and experimental melanoma metastases reflects the requirements for tumor formation.
Melanoma
Expression of membrane type 1 matrix metalloproteinase (MT1-MMP) in A2058 melanoma cells is associated with MMP-2 activation and increased tumor growth and vascularization.
Melanoma
Filamin A-mediated down-regulation of the exchange factor Ras-GRF1 correlates with decreased matrix metalloproteinase-9 expression in human melanoma cells.
Melanoma
Fully human antibodies to MCAM/MUC18 inhibit tumor growth and metastasis of human melanoma.
Melanoma
Fully humanized neutralizing antibodies to interleukin-8 (ABX-IL8) inhibit angiogenesis, tumor growth, and metastasis of human melanoma.
Melanoma
Gallic acid inhibits the migration and invasion of A375.S2 human melanoma cells through the inhibition of matrix metalloproteinase-2 and Ras.
Melanoma
Glucose transporter isoform 1 expression enhances metastasis of malignant melanoma cells.
Melanoma
Gold(I) Biscarbene Complexes Derived from Vascular-Disrupting Combretastatin A-4 Address Different Targets and Show Antimetastatic Potential.
Melanoma
Gonadotropin-releasing hormone agonists suppress melanoma cell motility and invasiveness through the inhibition of alpha3 integrin and MMP-2 expression and activity.
Melanoma
Halogenated bis(methoxy-benzylidene)-4-piperidone curcuminoids with improved anticancer activity.
Melanoma
HDAC-inhibitor (S)-8 disrupts HDAC6-PP1 complex prompting A375 melanoma cell growth arrest and apoptosis.
Melanoma
Highly invasive melanoma cells activate the vascular endothelium via an MMP-2/integrin ?v?5-induced secretion of VEGF-A.
Melanoma
Human hemokinin-1 promotes migration of melanoma cells and increases MMP-2 and MT1-MMP expression by activating tumor cell NK1 receptors.
Melanoma
Human hepatoma cells produce an 85 kDa gelatinase regulated by phorbol 12-myristate 13-acetate.
Melanoma
Human melanoma cell invasion is inhibited in vitro by swainsonine and deoxymannojirimycin with a concomitant decrease in collagenase IV expression.
Melanoma
Hyaluronan-binding protein 1 (HABP1/p32/gC1qR) induces melanoma cell migration and tumor growth by NF-kappa B dependent MMP-2 activation through integrin ?(v)?(3) interaction.
Melanoma
Hypoxia influences vasculogenic mimicry channel formation and tumor invasion-related protein expression in melanoma.
Melanoma
Hypoxia-induced senescence contributes to the regulation of microenvironment in melanomas.
Melanoma
Identification of activated matrix metalloproteinase-2 (MMP-2) as the main gelatinolytic enzyme in malignant melanoma by in situ zymography.
Melanoma
Identification of AP-2-regulated genes by macroarray profiling of gene expression in human A375P melanoma.
Melanoma
Identification of arachidonic acid pathways required for the invasive and metastatic activity of malignant tumor cells.
Melanoma
Identification of the 170-kDa melanoma membrane-bound gelatinase (seprase) as a serine integral membrane protease.
Melanoma
Immunohistochemical expression of vascular endothelial growth factor, matrix metalloproteinase 2, and matrix metalloproteinase 9 in cutaneous melanocytic lesions.
Melanoma
Immunolocalisation studies of matrix metalloproteinases-1, -2 and -3 in human melanoma.
Melanoma
In Vitro Methods to Study the Modulation of Migration and Invasion by Sphingosine-1-Phosphate.
Melanoma
In vivo and in vitro antitumor effect of ascorbic acid, lysine, proline and green tea extract on human melanoma cell line A2058.
Melanoma
In vivo antitumoral effect of 4-nerolidylcatechol (4-NC) in NRAS-mutant human melanoma.
Melanoma
Increased expression of neuropilin 1 in melanoma progression and its prognostic significance in patients with melanoma.
Melanoma
Independent expression and cellular processing of Mr 72,000 type IV collagenase and interstitial collagenase in human tumorigenic cell lines.
Melanoma
Induction of secreted matrix metalloproteinase-9 activity in human melanoma cells by extracellular matrix proteins and cytokines.
Melanoma
Inflammation and melanoma growth and metastasis: the role of platelet-activating factor (PAF) and its receptor.
Melanoma
Influence of cultured dermal fibroblasts on human melanoma cell proliferation, matrix metalloproteinase-2 (MMP-2) expression and invasion in vitro.
Melanoma
Inhibition of PKCalpha decreases the gelatinase activity and the angiogenic and metastatic ability of the highly metastatic B16 murine melanoma cells.
Melanoma
Inhibition of the Epigenetic Reader BRD4 Reduces SIRP?-Mediated Phagocytosis and Melanoma Invasion.
Melanoma
Inhibition of the STAT3 Signaling Pathway Contributes to the Anti-Melanoma Activities of Shikonin.
Melanoma
Inhibition of tumor growth by ?-elemene through downregulation of the expression of uPA, uPAR, MMP-2, and MMP-9 in a murine intraocular melanoma model.
Melanoma
Inhibitory effect of norcantharidin on melanoma tumor growth and vasculogenic mimicry by suppressing MMP-2 expression.
Melanoma
Intact vitronectin induces matrix metalloproteinase-2 and tissue inhibitor of metalloproteinases-2 expression and enhanced cellular invasion by melanoma cells.
Melanoma
Integrin alpha5beta1 controls invasion of human breast carcinoma cells by direct and indirect modulation of MMP-2 collagenase activity.
Melanoma
Intertumor heterogeneity in vascularity and invasiveness of artificial melanoma brain metastases.
Melanoma
Invasion-associated MMP-2 and MMP-9 are up-regulated intracellularly in concert with apoptosis linked to melanoma cell detachment.
Melanoma
Involvement of CD44 in matrix metalloproteinase-2 regulation in human melanoma cells.
Melanoma
Involvement of tumor cell integrin alpha v beta 3 in hematogenous metastasis of human melanoma cells.
Melanoma
Lipid-soluble ginseng extract inhibits invasion and metastasis of B16F10 melanoma cells.
Melanoma
Liver metastasis formation by laminin-1 peptide (LQVQLSIR)-adhesion selected B16-F10 melanoma cells.
Melanoma
LKB1 loss cooperating with BRAF V600E promotes melanoma cell invasion and migration by up-regulation MMP-2 via PI3K/Akt/mTOR pathway.
Melanoma
LncRNA GAS5 is a critical regulator of metastasis phenotype of melanoma cells and inhibits tumor growth in vivo.
Melanoma
Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin alpha v beta 3.
Melanoma
Locally generated VGVAPG and VAPG elastin-derived peptides amplify melanoma invasion via the galectin-3 receptor.
Melanoma
Long noncoding RNA HOTAIR is associated with motility, invasion, and metastatic potential of metastatic melanoma.
Melanoma
Loss of AP-2 results in up-regulation of MCAM/MUC18 and an increase in tumor growth and metastasis of human melanoma cells.
Melanoma
Loss of cell invasiveness through PKC-mediated syndecan-1 downregulation in melanoma cells under anchorage independency.
Melanoma
Loss of dipeptidyl peptidase IV immunostaining discriminates malignant melanomas from deep penetrating nevi.
Melanoma
Luteolin inhibits proliferation and induces apoptosis of human melanoma cells in vivo and in vitro by suppressing MMP-2 and MMP-9 through the PI3K/AKT pathway.
Melanoma
Matrix metalloproteinase expression in malignant melanomas: tumor-extracellular matrix interactions in invasion and metastasis.
Melanoma
Matrix metalloproteinase induction in the tumor stroma does not depend on CD147 expression in murine B16 melanoma.
Melanoma
Matrix metalloproteinase-2 (72 kD type IV collagenase) expression occurs in the early stage of human melanocytic tumour progression and may have prognostic value.
Melanoma
Matrix metalloproteinase-2 (MMP-2) immunoreactive protein--a new prognostic marker in uveal melanoma?
Melanoma
Matrix Metalloproteinase-2 Conditions Human Dendritic Cells to Prime Inflammatory T(H)2 Cells via an IL-12- and OX40L-Dependent Pathway.
Melanoma
Matrix metalloproteinase-2 is expressed in melanoma-associated spongiform scleropathy.
Melanoma
Matrix metalloproteinase-2 Promotes ?v?3 Integrin-Mediated Adhesion and Migration of Human Melanoma Cells by Cleaving Fibronectin.
Melanoma
Matrix metalloproteinases in human melanoma cell lines and xenografts: increased expression of activated matrix metalloproteinase-2 (MMP-2) correlates with melanoma progression.
Melanoma
Matrix metalloproteinases MMP-1, MMP-2, and MMP-13 are overexpressed in primary nodular melanoma.
Melanoma
MDA-9/Syntenin Is Essential for Factor VIIa-induced Signaling, Migration, and Metastasis in Melanoma Cells.
Melanoma
Mediation of NGF-stimulated extracellular matrix invasion by the human melanoma low-affinity p75 neurotrophin receptor: melanoma p75 functions independently of trkA.
Melanoma
Melanocytes in nevi and melanomas synthesize basement membrane and basement membrane-like material. An immunohistochemical and electron microscopic study including immunoelectron microscopy.
Melanoma
Melanoma Cell Resistance to Vemurafenib Modifies Inter-Cellular Communication Signals.
Melanoma
Melanoma differentiation-associated gene-7/interleukin 24 inhibits invasion and migration of human cervical cancer cells in vitro.
Melanoma
Melanoma invasion in reconstructed human skin is influenced by skin cells--investigation of the role of proteolytic enzymes.
Melanoma
Microtubule-dependent matrix metalloproteinase-2/matrix metalloproteinase-9 exocytosis: prerequisite in human melanoma cell invasion.
Melanoma
MMP-2 and TIMP-2 in Cutaneous Melanoma: Association With Prognostic Factors and Description in Cutaneous Metastases.
Melanoma
MMP-2 expression in uveal melanoma: differential activation status dictated by the cellular environment.
Melanoma
MMP-2, TIMP-2 and MT1-MMP are differentially expressed in lesional skin of melanocytic nevi and their expression is modulated by UVB-light.
Melanoma
MMP-9 is predominantly expressed in epithelioid and not spindle cell uveal melanoma.
Melanoma
Modulation of MMP-2 and -9 secretion by cytokines, inducers and inhibitors in human melanoma A-2058 cells.
Melanoma
Molecular basis for the critical role of suppressor of cytokine signaling-1 in melanoma brain metastasis.
Melanoma
Molecular cloning of seprase: a serine integral membrane protease from human melanoma.
Melanoma
Monocyte membrane type 1-matrix metalloproteinase. Prostaglandin-dependent regulation and role in metalloproteinase-2 activation.
Melanoma
NADPH oxidase 1 overexpression enhances invasion via matrix metalloproteinase-2 and epithelial-mesenchymal transition in melanoma cells.
Melanoma
Neural cell adhesion molecule potentiates invasion and metastasis of melanoma cells through CAMP-dependent protein kinase and phosphatidylinositol 3-kinase pathways.
Melanoma
Neuropilin-1 expression promotes invasiveness of melanoma cells through vascular endothelial growth factor receptor-2-dependent and -independent mechanisms.
Melanoma
Non-thermal atmospheric pressure plasmas as a novel candidate for preventive therapy of melanoma.
Melanoma
Nonlethal Levels of Zeaxanthin Inhibit Cell Migration, Invasion, and Secretion of MMP-2 via NF-?B Pathway in Cultured Human Uveal Melanoma Cells.
Melanoma
NRAGE suppresses metastasis of melanoma and pancreatic cancer in vitro and in vivo.
Melanoma
Nucleosome assembly protein 1-like 4, a new therapeutic target for proliferation and invasion of melanoma cells.
Melanoma
Osteopontin induces nuclear factor kappa B-mediated promatrix metalloproteinase-2 activation through I kappa B alpha /IKK signaling pathways, and curcumin (diferulolylmethane) down-regulates these pathways.
Melanoma
Osteopontin stimulates tumor growth and activation of promatrix metalloproteinase-2 through nuclear factor-kappa B-mediated induction of membrane type 1 matrix metalloproteinase in murine melanoma cells.
Melanoma
Osteopontin: it's role in regulation of cell motility and nuclear factor kappa B-mediated urokinase type plasminogen activator expression.
Melanoma
Overexpression of Hsp27 affects the metastatic phenotype of human melanoma cells in vitro.
Melanoma
Oxalomalate suppresses metastatic melanoma through IDH-targeted stress response to ROS.
Melanoma
Oxytocin involves in chronic stress-evoked melanoma metastasis via ?-arrestin 2-mediated ERK signaling pathway.
Melanoma
Paired Basic Amino Acid-cleaving Enzyme 4 (PCSK6): An Emerging New Target Molecule in Human Melanoma.
Melanoma
Phosphoinositide 3-kinase regulates membrane Type 1-matrix metalloproteinase (MMP) and MMP-2 activity during melanoma cell vasculogenic mimicry.
Melanoma
PKC and PKA phosphorylation affect the subcellular localization of claudin-1 in melanoma cells.
Melanoma
Plasmacytoid dendritic cells support melanoma progression by promoting Th2 and regulatory immunity through OX40L and ICOSL.
Melanoma
Platelet-activating factor mediates MMP-2 expression and activation via phosphorylation of cAMP-response element-binding protein and contributes to melanoma metastasis.
Melanoma
Polysaccharide from Inonotus obliquus inhibits migration and invasion in B16-F10 cells by suppressing MMP?2 and MMP?9 via downregulation of NF-?B signaling pathway.
Melanoma
Potential MMP2-mediated availability of HLA binding, mutant ECM peptides reflects better melanoma survival rates and greater T-cell infiltrates.
Melanoma
Predicting Novel Antitumor Agents: 3D-Pharmacophore Mapping of ?-N-biaryl Ether Sulfonamide-Based Hydroxamates as Potentially MMP-2 Inhibitors.
Melanoma
Progelatinase A mRNA expression in cell lines derived from tumors in patients with metastatic renal cell carcinoma correlates inversely with survival.
Melanoma
Prognostic significance of KAI1/CD82 in human melanoma and its role in cell migration and invasion through the regulation of ING4.
Melanoma
Prognostic significance of the expression of nuclear eukaryotic translation initiation factor 5A2 in human melanoma.
Melanoma
Prognostic value of MMP-2 immunoreactive protein (72 kD type IV collagenase) in primary skin melanoma.
Melanoma
PSY-1, a Taxus chinensis var. mairei extract, inhibits cancer cell metastasis by interfering with MMPs.
Melanoma
Quantitative analysis of melanocytic tissue array reveals inverse correlation between activator protein-2alpha and protease-activated receptor-1 expression during melanoma progression.
Melanoma
Reciprocal effects of ascorbate on cancer cell growth and the expression of matrix metalloproteinases and transforming growth factor-beta.
Melanoma
Recombinant interferon alpha and gamma modulate the invasive potential of human melanoma in vitro.
Melanoma
Repurposing of the anti-helminthic drug niclosamide to treat melanoma and pulmonary metastasis via the STAT3 signaling pathway.
Melanoma
Retinoid-mediated suppression of tumor invasion and matrix metalloproteinase synthesis.
Melanoma
RNA m6A methyltransferase METTL3 regulates invasiveness of melanoma cells by matrix metallopeptidase 2.
Melanoma
Role of ?-catenin signaling in the anti-invasive effect of the omega-3 fatty acid DHA in human melanoma cells.
Melanoma
Selection of invasive and metastatic subpopulations from a heterogeneous human melanoma cell line.
Melanoma
Serum matrix metalloproteinase-2 as a prognostic marker in advanced cutaneous melanoma.
Melanoma
Specific interaction between chitosan and matrix metalloprotease 2 decreases the invasive activity of human melanoma cells.
Melanoma
Stable overexpression of Smad7 in human melanoma cells inhibits their tumorigenicity in vitro and in vivo.
Melanoma
Stat3 activation regulates the expression of matrix metalloproteinase-2 and tumor invasion and metastasis.
Melanoma
Stimulation of the 92-kD type IV collagenase promoter and enzyme expression in human melanoma cells.
Melanoma
Stromal cells as the major source for matrix metalloproteinase-2 in cutaneous melanoma.
Melanoma
Suppression of basement membrane type IV collagen degradation and cell invasion in human melanoma cells expressing an antisense RNA for MMP-1.
Melanoma
Synthesis and antimetastatic activity evaluation of cinnamic acid derivatives containing 1,2,3-triazolic portions.
Melanoma
Synthesis and exploration of a novel chlorobenzylated 2-aminothiazole-phenyltriazole hybrid as migratory inhibitor of B16F10 in melanoma cells.
Melanoma
Synthetic emmprin peptides inhibit tumor cell-fibroblast interaction-stimulated upregulation of MMP-2 and tumor cell invasion.
Melanoma
Targeting melanoma growth and metastasis with systemic delivery of liposome-incorporated protease-activated receptor-1 small interfering RNA.
Melanoma
Targeting surface nucleolin with a multivalent pseudopeptide delays development of spontaneous melanoma in RET transgenic mice.
Melanoma
Targeting the tumor microenvironment with chemically modified tetracyclines: inhibition of laminin 5 gamma2 chain promigratory fragments and vasculogenic mimicry.
Melanoma
Tetraspanin CD9 induces MMP-2 expression by activating p38 MAPK, JNK and c-Jun pathways in human melanoma cells.
Melanoma
The 72 kDa type IV collagenase is modulated via differential expression of alpha v beta 3 and alpha 5 beta 1 integrins during human melanoma cell invasion.
Melanoma
The disintegrin-like and cysteine-rich domains of ADAM-9 mediate interactions between melanoma cells and fibroblasts.
Melanoma
The effect of ultraviolet radiation on choroidal melanocytes and melanoma cell lines: cell survival and matrix metalloproteinase production.
Melanoma
The expression of MMP-2 and Ki-67 in head and neck melanoma, and their correlation with clinic-pathologic indices.
Melanoma
The increased expression of Y box-binding protein 1 in melanoma stimulates proliferation and tumor invasion, antagonizes apoptosis and enhances chemoresistance.
Melanoma
The influence of different microenvironments on melanoma invasiveness and microcirculation patterns: an animal experiment study in the mouse model.
Melanoma
The Interplay of MicroRNA-34a, LGR4, EMT-Associated Factors, and MMP2 in Regulating Uveal Melanoma Cells.
Melanoma
The Metastatic Microenvironment: Melanoma-Microglia Cross-Talk Promotes the Malignant Phenotype of Melanoma Cells.
Melanoma
The tumour suppressor p33ING1 does not regulate migration and angiogenesis in melanoma cells.
Melanoma
TIMP-2: identification and characterization of a new member of the metalloproteinase inhibitor family.
Melanoma
Tissue biomarkers for prognosis in cutaneous melanoma: a systematic review and meta-analysis.
Melanoma
Tissue inhibitor of matrix metalloproteinase-2 regulates matrix metalloproteinase-2 activation by modulation of membrane-type 1 matrix metalloproteinase activity in high and low invasive melanoma cell lines.
Melanoma
Tissue inhibitor of metalloproteinase (TIMP-2). A new member of the metalloproteinase inhibitor family.
Melanoma
Tissue inhibitor of metalloproteinases-2 (TIMP-2) mRNA expression in tumor cell lines and human tumor tissues.
Melanoma
Tissue Rebuilding During Spontaneous Regression of Melanoma in the Melanoma-bearing Libechov Minipig.
Melanoma
TNF-alpha increases human melanoma cell invasion and migration in vitro: the role of proteolytic enzymes.
Melanoma
Transmembrane/cytoplasmic domain-mediated membrane type 1-matrix metalloprotease docking to invadopodia is required for cell invasion.
Melanoma
Up-regulating ribonuclease inhibitor inhibited epithelial-to-mesenchymal transition and metastasis in murine melanoma cells.
Melanoma
Vemurafenib resistance increases melanoma invasiveness and modulates the tumor microenvironment by MMP-2 upregulation.
Melanoma
Wild-type p53 gene transfer inhibits invasion and reduces matrix metalloproteinase-2 levels in p53-mutated human melanoma cells.
Melanoma
[4-acetamidophenyl retinoate (4-APR) inhibits reconstituted basement membrane invasion by tumor cells and its mechanism]
Melanoma
[Correlation between the biological behavior and invasion potential in three mouse melanoma cell lines]
Melanoma
[Role of matrix metalloproteinases (MMPs) in tumor invasion and metastasis: serial studies on MMPs and TIMPs]
Melanoma
[The influence of different microenvironments on melanoma invasiveness and microcirculation patterns]
Melanoma
[The mechanisms of microenvironments influence on vasculogenic mimicry between introcular and subcutaneous melanoma]
Melanoma, Experimental
Differences in expression of metalloproteinases and plasminogen activators in murine melanocytes and B16 melanoma variants: lack of association with in vitro invasion.
Melanoma, Experimental
Induction of 103-kDa gelatinase/type IV collagenase by acidic culture conditions in mouse metastatic melanoma cell lines.
Melanoma, Experimental
Matrix metalloproteinase induction in the tumor stroma does not depend on CD147 expression in murine B16 melanoma.
Melanoma, Experimental
Modulation of plasminogen activation and type IV collagenase activity by a synthetic peptide derived from the laminin A chain.
Melkersson-Rosenthal Syndrome
Expression of protease-activated receptor-1 and -2 in orofacial granulomatosis.
Meningeal Carcinomatosis
Specific matrix metalloproteinase profiles in the cerebrospinal fluid correlated with the presence of malignant astrocytomas, brain metastases, and carcinomatous meningitis.
Meningioma
Correlation of clinical and biological parameters with peritumoral edema in meningioma.
Meningioma
Differential expression of extracellular matrix-related genes in rare variants of meningioma.
Meningioma
Ets-1 is up-regulated together with its target gene products matrix metalloproteinase-2 and matrix metalloproteinase-9 in atypical and anaplastic meningiomas.
Meningioma
Expression of extracellular matrix-degrading proteins in classic, atypical, and anaplastic meningiomas.
Meningioma
Expression of matrix metalloproteinases 2 and 9 in meningiomas associated with different degrees of brain invasiveness and edema.
Meningioma
Expression of matrix metalloproteinases, their inhibitors, and urokinase plasminogen activator in human meningiomas.
Meningioma
Expression of MMP-2 and -9 in short-term cultures of meningioma: influence of histological subtype.
Meningioma
Expression of MMP-2 and MMP-9 in Benign Canine Rostrotentorial Meningiomas Is Not Correlated to the Extent of Peritumoral Edema.
Meningioma
Gene Expression of Matrix Metalloproteinases and their Inhibitors (TIMPs) in Meningiomas of Dogs.
Meningioma
Increased expression of avian erythroblastosis virus E26 oncogene homolog 1 in World Health Organization grade 1 meningiomas is associated with an elevated risk of recurrence and is correlated with the expression of its target genes matrix metalloproteinase-2 and MMP-9.
Meningioma
Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9 expression in the biological behavior of Canine and Feline Meningioma.
Meningioma
Matrix metalloproteinase-2 and matrix metalloproteinase-9 expressions correlate with the recurrence of intracranial meningiomas.
Meningioma
Possible role of matrix metalloproteinase in osteolytic intracranial meningiomas.
Meningioma
Possible role of matrix metalloproteinases (MMPs) in hyperostosis of intracranial meningiomas.
Meningioma
Presence of matrix metalloproteinase-2 and tissue inhibitor matrix metalloproteinase-2 gene polymorphisms and immunohistochemical expressions in intracranial meningiomas.
Meningioma
The effects of exogenous growth factors on matrix metalloproteinase secretion by human brain tumour cells.
Meningioma
The role of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinase in microcystic meningiomas.
Meningitis
Association of matrix metalloproteinase-9 and tissue inhibitors of metalloproteinase-4 in cerebrospinal fluid with blood-brain barrier dysfunction in patients with eosinophilic meningitis caused by Angiostrongylus cantonensis.
Meningitis
Association of matrix metalloproteinase-9 in eosinophilic meningitis of BALB/c mice caused by Angiostrongylus cantonensis.
Meningitis
Effects of purulent meningitis on the changes of matrix metalloproteinase-2 (MMP-2) and matrix metalloproteinase inhibitor-1 (TIMP-1) in cerebrospinal fluid of neonates.
Meningitis
Expression of MMP-2 and TIMP-1 in cerebrospinal fluid and the correlation with dynamic changes of serum PCT in neonatal purulent meningitis.
Meningitis
Gelatinase activity of matrix metalloproteinases in the cerebrospinal fluid of various patient populations.
Meningitis
Induction of matrix metalloproteinase-9 in murine eosinophilic meningitis caused by Angiostrongylus cantonensis.
Meningitis
Marked increase of matrix metalloproteinase 9 in cerebrospinal fluid of patients with fungal or tuberculous meningoencephalitis.
Meningitis
Matrix metalloprotease-9 in cerebrospinal fluid correlates with disease activity in lymphomatous meningitis.
Meningitis
Serum Matrix Metalloproteinase-2 Levels Indicate Blood-CSF Barrier Damage in Patients with Infectious Meningitis.
Meningitis, Aseptic
Persistent increase of matrix metalloproteinases in cerebrospinal fluid of tuberculous meningitis.
Meningitis, Bacterial
Dexamethasone regulation of matrix metalloproteinase expression in experimental pneumococcal meningitis.
Meningitis, Bacterial
Experimental pneumococcal meningitis in rabbits: the increase of matrix metalloproteinase-9 in cerebrospinal fluid correlates with leucocyte invasion.
Meningitis, Bacterial
Immunohistochemical analysis of MMP-9, MMP-2 and TIMP-1, TIMP-2 expression in the central nervous system following infection with viral and bacterial meningitis.
Meningitis, Bacterial
Matrix metalloproteinase (MMP)-8 and MMP-9 in cerebrospinal fluid during bacterial meningitis: association with blood-brain barrier damage and neurological sequelae.
Meningitis, Bacterial
Serum Matrix Metalloproteinase-2 Levels Indicate Blood-CSF Barrier Damage in Patients with Infectious Meningitis.
Meningitis, Pneumococcal
Dexamethasone regulation of matrix metalloproteinase expression in experimental pneumococcal meningitis.
Meningitis, Pneumococcal
Inhibition of matrix metalloproteinases-2 and -9 prevents cognitive impairment induced by pneumococcal meningitis in Wistar rats.
Meningitis, Viral
Matrix metalloproteinases and tissue inhibitors of metalloproteinases in viral meningitis: upregulation of MMP-9 and TIMP-1 in cerebrospinal fluid.
Menorrhagia
Menstrual activity of matrix metalloproteinases is decreased in endometrium regenerating after thermal ablation.
Menorrhagia
Reduced levels of VEGF-A and MMP-2 and MMP-9 activity and increased TNF-alpha in menstrual endometrium and effluent in women with menorrhagia.
Mesothelioma
3-O-Methylfunicone, a metabolite produced by Penicillium pinophilum, modulates ERK1/2 activity, affecting cell motility of human mesothelioma cells.
Mesothelioma
ERK1/2 and p38 MAP kinase control MMP-2, MT1-MMP, and TIMP action and affect cell migration: A comparison between mesothelioma and mesothelial cells.
Mesothelioma
Proteasomal degradation of polycomb-group protein CBX6 confers MMP-2 expression essential for mesothelioma invasion.
Mesothelioma, Malignant
3-D collagen-dependent cell surface expression of MT1-MMP and MMP-2 activation regardless of integrin ?1 function and matrix stiffness.
Mesothelioma, Malignant
Modulation of MMP-2 and MMP-9 by cytokines, mitogens and inhibitors in lung cancer and malignant mesothelioma cell lines.
Mesothelioma, Malignant
Regulation of matrix metalloprotease activity in malignant mesothelioma cell lines by growth factors.
Metabolic Syndrome
Do different bariatric surgical procedures influence plasma levels of matrix metalloproteinase-2, -7, and -9 among patients with type 2 diabetes mellitus?
Metabolic Syndrome
Effect of metabolic syndrome risk factors and MMP-2 genetic variations on circulating MMP-2 levels in childhood obesity.
Metabolic Syndrome
MMPs 2 and 9 are essential for coronary collateral growth and are prominently regulated by p38 MAPK.
Metabolic Syndrome
Modulation of Systemic Metabolism by MMP-2: From MMP-2 Deficiency in Mice to MMP-2 Deficiency in Patients.
Metabolic Syndrome
Vitamin D supplementation has no effect on matrix metalloproteinases-2, -9, and tissue inhibitor matrix metalloproteinase-1 in subjects with metabolic syndrome: A pilot study.
Metrorrhagia
Differential elevation of matrix metalloproteinase expression in women exposed to levonorgestrel-releasing intrauterine system for a short or prolonged period of time.
Migraine Disorders
Acupuncture decreases matrix metalloproteinase-2 activity in patients with migraine.
Migraine Disorders
Matrix metalloproteinase (MMP)-2 gene polymorphisms affect circulating MMP-2 levels in patients with migraine with aura.
Migraine Disorders
New implications of the proteolytic balance between matrix metalloproteinases and their tissue inhibitors in migraine with and without aura.
Migraine Disorders
Serum levels of matrix metalloproteinases: implications in clinical neurology.
Migraine with Aura
Matrix metalloproteinase (MMP)-2 gene polymorphisms affect circulating MMP-2 levels in patients with migraine with aura.
Migraine without Aura
Serum levels of matrix metalloproteinases: implications in clinical neurology.
Mitral Valve Insufficiency
[Involvement of matrix metalloproteinases in the regulation of myocardial extracellular matrix in patients with congestive heart failure]
Mitral Valve Prolapse
Cardiac transgenic matrix metalloproteinase-2 expression induces myxomatous valve degeneration: a potential model of mitral valve prolapse disease.
Mitral Valve Prolapse
Investigation of the Matrix Metalloproteinase-2 Gene in Patients with Non-Syndromic Mitral Valve Prolapse.
Mouth Neoplasms
Antimetastatic Effects of Sesamin on Human Head and Neck Squamous Cell Carcinoma through Regulation of Matrix Metalloproteinase-2.
Mouth Neoplasms
Assessment of MicroRNA (miR)-365 Effects on Oral Squamous Carcinoma Cell Line Phenotypes.
Mouth Neoplasms
Caffeic Acid phenethyl ester inhibits oral cancer cell metastasis by regulating matrix metalloproteinase-2 and the mitogen-activated protein kinase pathway.
Mouth Neoplasms
Calreticulin, an endoplasmic reticulum-resident protein, is highly expressed and essential for cell proliferation and migration in oral squamous cell carcinoma.
Mouth Neoplasms
Coexpression of growth differentiation factor 11 and reactive oxygen species in metastatic oral cancer and its role in inducing the epithelial to mesenchymal transition.
Mouth Neoplasms
Combined evaluation of matrix metalloproteinases and their inhibitors has better clinical utility in oral cancer.
Mouth Neoplasms
Correlations of oral tongue cancer invasion with matrix metalloproteinases (MMPs) and vascular endothelial growth factor (VEGF) expression.
Mouth Neoplasms
Corrigendum to "Caffeic Acid Phenethyl Ester Inhibits Oral Cancer Cell Metastasis by Regulating Matrix Metalloproteinase-2 and the Mitogen-Activated Protein Kinase Pathway".
Mouth Neoplasms
Curcumin Inhibits Invasiveness and Epithelial-Mesenchymal Transition in Oral Squamous Cell Carcinoma Through Reducing Matrix Metalloproteinase 2, 9 and Modulating p53-E-Cadherin Pathway.
Mouth Neoplasms
Dehydroandrographolide inhibits oral cancer cell migration and invasion through NF-?B-, AP-1-, and SP-1-modulated matrix metalloproteinase-2 inhibition.
Mouth Neoplasms
Dioscorea nipponica Makino inhibits migration and invasion of human oral cancer HSC-3 cells by transcriptional inhibition of matrix metalloproteinase-2 through modulation of CREB and AP-1 activity.
Mouth Neoplasms
Duchesnea indica extract attenuates oral cancer cells metastatic potential through the inhibition of the matrix metalloproteinase-2 activity by down-regulating the MEK/ERK pathway.
Mouth Neoplasms
Epigallocatechin-3-gallate inhibits the invasion of human oral cancer cells and decreases the productions of matrix metalloproteinases and urokinase-plasminogen activator.
Mouth Neoplasms
Expression and clinical significance of matrix metalloproteinase-2 and matrix metalloproteinase-9 in oral squamous cell carcinoma.
Mouth Neoplasms
Expression of FLJ10540 is correlated with aggressiveness of oral cavity squamous cell carcinoma by stimulating cell migration and invasion through increased FOXM1 and MMP-2 activity.
Mouth Neoplasms
Expression of matrix metalloproteinase-2 related to lymph node metastasis of oral squamous cell carcinoma. A clinicopathologic study.
Mouth Neoplasms
Gallic acid inhibits migration and invasion of SCC-4 human oral cancer cells through actions of NF-?B, Ras and matrix metalloproteinase-2 and -9.
Mouth Neoplasms
Geraniin inhibits oral cancer cell migration by suppressing matrix metalloproteinase-2 activation through the FAK/Src and ERK pathways.
Mouth Neoplasms
Increased expression and activation of matrix metalloproteinase-2 (MMP-2) in O-1N: hamster oral squamous cell carcinoma with high potential lymph node metastasis.
Mouth Neoplasms
Inhibition of gelatinase activity by cyclic peptides--A support for oral cancer treatment?
Mouth Neoplasms
Kaempferol reduces matrix metalloproteinase-2 expression by down-regulating ERK1/2 and the activator protein-1 signaling pathways in oral cancer cells.
Mouth Neoplasms
Luteolin-7-O-Glucoside Inhibits Oral Cancer Cell Migration and Invasion by Regulating Matrix Metalloproteinase-2 Expression and Extracellular Signal-Regulated Kinase Pathway.
Mouth Neoplasms
Matrix metalloproteinase 2 and matrix metalloproteinase 9 expression in human oral squamous cell carcinoma and the effect of protein kinase C inhibitors: preliminary observations.
Mouth Neoplasms
Matrix metalloproteinase-13 is a target gene of high-mobility group box-containing protein 1 in modulating oral cancer cell invasion.
Mouth Neoplasms
Matrix metalloproteinases and their inhibitors: correlation with invasion and metastasis in oral cancer.
Mouth Neoplasms
Oral submucous fibrosis stimulates invasion and epithelial-mesenchymal transition in oral squamous cell carcinoma by activating MMP-2 and IGF-IR.
Mouth Neoplasms
Paclitaxel induces apoptosis and reduces proliferation by targeting epidermal growth factor receptor signaling pathway in oral cavity squamous cell carcinoma.
Mouth Neoplasms
Phenethyl isothiocyanate suppresses EGF-stimulated SAS human oral squamous carcinoma cell invasion by targeting EGF receptor signaling.
Mouth Neoplasms
Pinostilbene Hydrate Suppresses Human Oral Cancer Cell Metastasis by Downregulation of Matrix Metalloproteinase-2 Through the Mitogen-Activated Protein Kinase Signaling Pathway.
Mouth Neoplasms
Pinosylvin reduced migration and invasion of oral cancer carcinoma by regulating matrix metalloproteinase-2 expression and extracellular signal-regulated kinase pathway.
Mouth Neoplasms
Pterostilbene suppresses oral cancer cell invasion by inhibiting MMP-2 expression.
Mouth Neoplasms
Quercetin inhibits cell viability, migration and invasion by regulating miR-16/HOXA10 axis in oral cancer.
Mouth Neoplasms
RNAi targeting urokinase-type plasminogen activator receptor inhibits metastasis and progression of oral squamous cell carcinoma in vivo.
Mouth Neoplasms
Rubus idaeus extract suppresses migration and invasion of human oral cancer by inhibiting MMP-2 through modulation of the Erk1/2 signaling pathway.
Mouth Neoplasms
Senescent cancer-associated fibroblasts secrete active MMP-2 that promotes keratinocyte dis-cohesion and invasion.
Mouth Neoplasms
Strong association of the tissue inhibitor of metalloproteinase-2 polymorphism with an increased risk of oral squamous cell carcinoma in Europeans.
Moyamoya Disease
Increased expression of serum matrix metalloproteinase-9 in patients with moyamoya disease.
Moyamoya Disease
The GC?+?CC genotype at position -418 in TIMP-2 promoter and the -1575GA/-1306CC genotype in MMP-2 is genetic predisposing factors for prevalence of moyamoya disease.
Mucocele
Immunohistochemical expression of matrix metalloproteinase-1, matrix metalloproteinase-2 and matrix metalloproteinase-9, myofibroblasts and Ki-67 in actinic cheilitis and lip squamous cell carcinoma.
Mucocutaneous Lymph Node Syndrome
Serum MMP-2 and MMP-9 in patients with Behçet's disease: Do their higher levels correlate to vasculo-Behçet's disease associated with aneurysm formation?
Mucocutaneous Lymph Node Syndrome
[Roles of matrix metalloproteinases, tissue inhibitor of matrix metalloproteinase and hs-CRP in Kawasaki disease]
Mucopolysaccharidoses
Spectrum of common and uncommon causes of knee joint hyaline cartilage degeneration and their key imaging features.
Mucositis
Correction: olmesartan decreased levels of IL-1? and TNF-?, down-regulated MMP-2, MMP-9, COX-2, RANK/RANKL and up-regulated SOCs-1 in an intestinal mucositis model.
Mucositis
Olmesartan decreased levels of IL-1? and TNF-?, down-regulated MMP-2, MMP-9, COX-2, RANK/RANKL and up-regulated SOCs-1 in an intestinal mucositis model.
Mucositis
Periodontal disease, peri-implant disease and levels of salivary biomarkers IL-1?, IL-10, RANK, OPG, MMP-2, TGF-? and TNF-?: follow-up over 5 years.
Multiple Myeloma
Bone marrow neovascularization, plasma cell angiogenic potential, and matrix metalloproteinase-2 secretion parallel progression of human multiple myeloma.
Multiple Myeloma
Cell-surface serglycin promotes adhesion of myeloma cells to collagen type I and affects the expression of matrix metalloproteinases.
Multiple Myeloma
Designing new generation of potent inhibitors against membrane-type matrix metalloproteinase-2: a computational effort against multiple myeloma.
Multiple Myeloma
Effect of wild type PTEN gene on proliferation and invasion of multiple myeloma.
Multiple Myeloma
Increased expression of metalloproteinase-2 and -9 (MMP-2, MMP-9), tissue inhibitor of metalloproteinase-1 and -2 (TIMP-1, TIMP-2), and EMMPRIN (CD147) in multiple myeloma.
Multiple Myeloma
Matrix metalloproteinases-1 and -2, and tissue inhibitor of metalloproteinase-2 production is abnormal in bone marrow stromal cells of multiple myeloma patients.
Multiple Myeloma
Proteolytic activity of human lymphoid tumor cells. Correlation with tumor progression.
Multiple Myeloma
Selective inhibition of matrix metalloproteinase-2 in the multiple myeloma-bone microenvironment.
Multiple Myeloma
The evaluation of angiogenesis and matrix metalloproteinase-2 secretion in bone marrow of multiple myeloma patients before and after the treatment.
Multiple Sclerosis
Analyses of all matrix metalloproteinase members in leukocytes emphasize monocytes as major inflammatory mediators in multiple sclerosis.
Multiple Sclerosis
Anti-inflammatory nutritional intervention in patients with relapsing-remitting and primary-progressive multiple sclerosis: A pilot study.
Multiple Sclerosis
Association of MMP-2 (?1306 C/T) Gene Polymorphism with Predisposition to Optic Neuritis and Optic Neuritis Together with Multiple Sclerosis.
Multiple Sclerosis
Engineering autoactivating forms of matrix metalloproteinase-9 and expression of the active enzyme in cultured cells and transgenic mouse brain.
Multiple Sclerosis
Functional Promoter Polymorphisms of MMP-2 C-735T and MMP-9 C-1562T and Their Synergism with MMP-7 A-181G in Multiple Sclerosis.
Multiple Sclerosis
Gelatinase B/matrix metalloproteinase-9 is a phase-specific effector molecule, independent from Fas, in experimental autoimmune encephalomyelitis.
Multiple Sclerosis
Gelatinase in the cerebrospinal fluid of patients with multiple sclerosis and other inflammatory neurological disorders.
Multiple Sclerosis
Gelatinases (MMP-2 and MMP-9) are preferentially expressed by Th1 vs. Th2 cells.
Multiple Sclerosis
Heterogeneity of serum gelatinases MMP-2 and MMP-9 isoforms and charge variants.
Multiple Sclerosis
Imaging matrix metalloproteinase activity in multiple sclerosis as a specific marker of leukocyte penetration of the blood-brain barrier.
Multiple Sclerosis
In vivo activation of gelatinase B/MMP-9 by trypsin in acute pancreatitis is a permissive factor in streptozotocin-induced diabetes.
Multiple Sclerosis
Interferon beta-1b inhibits gelatinase secretion and in vitro migration of human T cells: a possible mechanism for treatment efficacy in multiple sclerosis.
Multiple Sclerosis
Interplay between Matrix Metalloproteinase-9, Matrix Metalloproteinase-2, and Interleukins in Multiple Sclerosis Patients.
Multiple Sclerosis
Leukocyte Gene Expression and Plasma Concentration in Multiple Sclerosis: Alteration of Transforming Growth Factor-?s, Claudin-11, and Matrix Metalloproteinase-2.
Multiple Sclerosis
Matrix metalloproteinase-9 (gelatinase B) is selectively elevated in CSF during relapses and stable phases of multiple sclerosis.
Multiple Sclerosis
Matrix metalloproteinase-9 and matrix metalloproteinase-2 as biomarkers of various courses in multiple sclerosis.
Multiple Sclerosis
Matrix metalloproteinase-9 and matrix metalloproteinase-2 gene polymorphisms in multiple sclerosis.
Multiple Sclerosis
Modulation of monocytes matrix metalloproteinase-2, MT1-MMP and TIMP-2 by interferon-gamma and -beta: implications to multiple sclerosis.
Multiple Sclerosis
Modulation of proteoglycan receptor PTP? enhances MMP-2 activity to promote recovery from multiple sclerosis.
Multiple Sclerosis
Multiple sclerosis: Association of gelatinase B/matrix metalloproteinase-9 with risk and clinical course the disease.
Multiple Sclerosis
Neutralizing antibodies against IFN-beta in multiple sclerosis: antagonization of IFN-beta mediated suppression of MMPs.
Multiple Sclerosis
PECAM-1 and gelatinase B coexist in vascular cuffs of multiple sclerosis lesions.
Multiple Sclerosis
Potential relevance of cerebrospinal fluid and serum levels and intrathecal synthesis of active matrix metalloproteinase-2 (MMP-2) as markers of disease remission in patients with multiple sclerosis.
Multiple Sclerosis
Proinflammatory cytokines and matrix metalloproteinases in CSF of patients with VZV vasculopathy.
Multiple Sclerosis
Serum gelatinase B/MMP-9 in primary progressive multiple sclerosis patients treated with interferon-beta-1a.
Multiple Sclerosis
Serum levels of matrix metalloproteinase-2, -9, and vitamin D in patients with multiple sclerosis with or without herpesvirus-6 seropositivity.
Multiple Sclerosis
Serum MMP-2 and MMP-9 are elevated in different multiple sclerosis subtypes.
Multiple Sclerosis
Serum MMP-9/TIMP-1 and MMP-2/TIMP-2 ratios in multiple sclerosis: relationships with different magnetic resonance imaging measures of disease activity during IFN-beta-1a treatment.
Multiple Sclerosis
The gelatinase inhibitory activity of tetracyclines and chemically modified tetracycline analogues as measured by a novel microtiter assay for inhibitors.
Multiple Sclerosis
The gelatinases, MMP-2 and MMP-9, as fine tuners of neuroinflammatory processes.
Multiple Sclerosis, Chronic Progressive
Serum gelatinase B/MMP-9 in primary progressive multiple sclerosis patients treated with interferon-beta-1a.
Multiple Sclerosis, Relapsing-Remitting
Anti-inflammatory nutritional intervention in patients with relapsing-remitting and primary-progressive multiple sclerosis: A pilot study.
Multiple Sclerosis, Relapsing-Remitting
Influence of combined functional resistance and endurance exercise over 12?weeks on matrix metalloproteinase-2 serum concentration in persons with relapsing-remitting multiple sclerosis - a community-based randomized controlled trial.
Muscular Atrophy
Electrical Stimulation of Denervated Rat Skeletal Muscle Retards Capillary and Muscle Loss in Early Stages of Disuse Atrophy.
Muscular Atrophy
Matrix metalloproteinase-2 expression and promoter/enhancer activity in skeletal muscle atrophy.
Muscular Atrophy
Role of AP-1 and RE-1 binding sites in matrix metalloproteinase-2 transcriptional regulation in skeletal muscle atrophy.
Muscular Diseases
Matrix metalloproteinase-2 ablation in dystrophin-deficient mdx muscles reduces angiogenesis resulting in impaired growth of regenerated muscle fibers.
Muscular Diseases
MMP-10 is required for efficient muscle regeneration in mouse models of injury and muscular dystrophy.
Muscular Dystrophies
Activation and localization of matrix metalloproteinase-2 and -9 in the skeletal muscle of the muscular dystrophy dog (CXMDJ).
Muscular Dystrophies
Metalloproteinase expression is altered in cardiac and skeletal muscle in cancer cachexia.
Muscular Dystrophies
The enzymatic processing of ?-dystroglycan by MMP-2 is controlled by two anchoring sites distinct from the active site.
Muscular Dystrophy, Duchenne
Matrix metalloproteinase-2 ablation in dystrophin-deficient mdx muscles reduces angiogenesis resulting in impaired growth of regenerated muscle fibers.
Muscular Dystrophy, Duchenne
MMP-10 is required for efficient muscle regeneration in mouse models of injury and muscular dystrophy.
Myasthenia Gravis
Selective localization of gelatinase A, an enzyme degrading beta-amyloid protein, in white matter microglia and in Schwann cells.
Myasthenia Gravis
Serum levels of matrix metalloproteinases: implications in clinical neurology.
Mycetoma
Active Matrix Metalloprotease-9 Is Associated with the Collagen Capsule Surrounding the Madurella mycetomatis Grain in Mycetoma.
Mycosis Fungoides
Proteolytic activity of human lymphoid tumor cells. Correlation with tumor progression.
Myelitis, Transverse
Cytokines and matrix metalloproteinases in the cerebrospinal fluid of patients with acute transverse myelitis: an outcome analysis.
Myelodysplastic Syndromes
Reduced expression of inducible gelatinase B/matrix metalloproteinase-9 in monocytes from patients with myelodysplastic syndrome: Correlation of inducible levels with the percentage of cytogenetically marked cells and with marrow cellularity.
Myelodysplastic Syndromes
Secretion and Expression of Matrix Metalloproteinase-2 and 9 from Bone Marrow Mononuclear Cells in Myelodysplastic Syndrome and Acute Myeloid Leukemia.
Myocardial Infarction
Association of matrix metalloproteinase-2 gene promoter polymorphism with myocardial infarction susceptibility in a Mexican population.
Myocardial Infarction
Change in matrix metalloproteinase 2, 3, and 9 levels at the time of and after acute atherothrombotic myocardial infarction.
Myocardial Infarction
Circulating level of gelatinase activity predicts ventricular remodeling in patients with acute myocardial infarction.
Myocardial Infarction
Correlation between acute myocardial infarction complicated with cerebral infarction and expression levels of MMP-2 and MMP-9.
Myocardial Infarction
Correlation between plasma angiopoietin-1, angiopoietin-2 and matrix metalloproteinase-2 in coronary heart disease.
Myocardial Infarction
Development of Matrix Metalloproteinase-2 Inhibitors for Cardioprotection.
Myocardial Infarction
Differential regulation of matrix metalloproteinase-2 and -9 expression and activity in adult rat cardiac fibroblasts in response to interleukin-1beta.
Myocardial Infarction
Early measurements of plasma matrix metalloproteinase-2 predict infarct size and ventricular dysfunction in ST-elevation myocardial infarction.
Myocardial Infarction
Effect of typhaneoside on ventricular remodeling and regulation of PI3K/Akt/mTOR pathway.
Myocardial Infarction
Effects of age, gender, ethnicity, diurnal variation and exercise on circulating levels of matrix metalloproteinases (MMP)-2 and -9, and their inhibitors, tissue inhibitors of matrix metalloproteinases (TIMP)-1 and -2.
Myocardial Infarction
EMMPRIN-Targeted Magnetic Nanoparticles for In Vivo Visualization and Regression of Acute Myocardial Infarction.
Myocardial Infarction
Enhanced cardiac production of matrix metalloproteinase-2 and -9 and its attenuation associated with pravastatin treatment in patients with acute myocardial infarction.
Myocardial Infarction
Enhanced matrix metalloproteinase activity in skeletal muscles of rats with congestive heart failure.
Myocardial Infarction
Enhancement of Matrix Metalloproteinase 2 and 9 Inhibitory Action of Minocycline by Aspirin: An Approach to Attenuate Outcome of Acute Myocardial Infarction in Diabetes.
Myocardial Infarction
Evaluation of (68)Ga-labeled peptide tracer for detection of gelatinase expression after myocardial infarction in rat.
Myocardial Infarction
Expressions and clinical significance of factors related to acute coronary syndrome.
Myocardial Infarction
Influence of interleukin-1 beta gene polymorphisms on the risk of myocardial infarction and ischemic stroke at young age in vivo and in vitro.
Myocardial Infarction
Intracellular Regulation of Matrix Metalloproteinase-2 Activity: New Strategies in Treatment and Protection of Heart Subjected to Oxidative Stress.
Myocardial Infarction
Matrix Metalloproteinase-2 Impairs Homing of Intracoronary Delivered Mesenchymal Stem Cells in a Porcine Reperfused Myocardial Infarction: Comparison With Intramyocardial Cell Delivery.
Myocardial Infarction
Matrix Metalloproteinase-2 Is Activated During Ischemia/Reperfusion in a Model of Myocardial Infarction.
Myocardial Infarction
Matrix Metalloproteinase-2 predicts mortality in patients with acute coronary syndrome.
Myocardial Infarction
Matrix metalloproteinases in patients with myocardial infarction and percutaneous revascularization.
Myocardial Infarction
Noninvasive Limb Ischemic Preconditioning Protects Against Myocardial I/R Injury in Rats.
Myocardial Infarction
Osthole ameliorates acute myocardial infarction in rats by decreasing the expression of inflammatory-related cytokines, diminishing MMP-2 expression and activating p-ERK.
Myocardial Infarction
Peripheral blood levels of matrix metalloproteases-2 and -9 are elevated in patients with acute coronary syndromes.
Myocardial Infarction
Plasma MMP-2, MMP-9 and N-BNP in long-term survivors following complicated myocardial infarction: relation to cardiac magnetic resonance imaging measures of left ventricular structure and function.
Myocardial Infarction
Plasma MMP-9 and MMP-2 following acute myocardial infarction in man: correlation with echocardiographic and neurohumoral parameters of left ventricular dysfunction.
Myocardial Infarction
Pravastatin suppresses the increase in matrix metalloproteinase-2 levels after acute myocardial infarction.
Myocardial Infarction
Predictive utility of the changes in matrix metalloproteinase-2 in the early phase for left ventricular reverse remodeling after an acute myocardial infarction.
Myocardial Infarction
Selective spatiotemporal induction of matrix metalloproteinase-2 and matrix metalloproteinase-9 transcription after myocardial infarction.
Myocardial Infarction
Serum levels of matrix metalloproteinases 2 and 9 in patients with acute myocardial infarction.
Myocardial Infarction
Serum metalloproteinase 9 levels in patients with coronary artery disease: a novel marker of inflammation.
Myocardial Infarction
Serum MMP-9 activity as a diagnosing marker for the developing heart failure of post MI patients.
Myocardial Infarction
Serum profiles of matrix metalloproteinases and their tissue inhibitor in patients with acute coronary syndromes. The effects of short-term atorvastatin administration.
Myocardial Infarction
Sesamol Attenuates Isoproterenol-induced Acute Myocardial Infarction via Inhibition of Matrix Metalloproteinase-2 and -9 Expression in Rats.
Myocardial Infarction
Sustained Release of a Peptide-Based Matrix Metalloproteinase-2 Inhibitor to Attenuate Adverse Cardiac Remodeling and Improve Cardiac Function Following Myocardial Infarction.
Myocardial Infarction
Targeted deletion of MMP-2 attenuates early LV rupture and late remodeling after experimental myocardial infarction.
Myocardial Infarction
Targeted deletion or pharmacological inhibition of MMP-2 prevents cardiac rupture after myocardial infarction in mice.
Myocardial Infarction
The p66ShcA adaptor protein regulates healing after myocardial infarction.
Myocardial Infarction
The role of matrix metalloproteinase-2 promoter polymorphisms in coronary artery disease and myocardial infarction.
Myocardial Infarction
Trimetazidine suppresses oxidative stress, inhibits MMP-2 and MMP-9 expression, and prevents cardiac rupture in mice with myocardial infarction.
Myocardial Infarction
Vitamin D is related to markers of vulnerable plaque in acute myocardial infarction.
Myocardial Infarction
[Analysis of the gene polymorphism of matrix metalloproteinase-2 and -9 in patients with coronary heart disease]
Myocardial Infarction
[Correlation between serum MMP-2 and MMP-9 in patients with acute myocardial infarction before and after PCI.]
Myocardial Ischemia
Calpain inhibitors exhibit matrix metalloproteinase-2 inhibitory activity.
Myocardial Ischemia
Enhancement of Matrix Metalloproteinase 2 and 9 Inhibitory Action of Minocycline by Aspirin: An Approach to Attenuate Outcome of Acute Myocardial Infarction in Diabetes.
Myocardial Ischemia
Inhibition of CD34+ cell migration by matrix metalloproteinase-2 during acute myocardial ischemia, counteracted by ischemic preconditioning.
Myocardial Ischemia
Intracellular action of matrix metalloproteinase-2 accounts for acute myocardial ischemia and reperfusion injury.
Myocardial Ischemia
Matrix metalloproteinase-2 contributes to tumor necrosis factor alpha induced apoptosis in cultured rat cardiac myocytes.
Myocardial Ischemia
Reduced MMP-2 activity contributes to cardiac fibrosis in experimental diabetic cardiomyopathy.
Myocardial Ischemia
[Correlation between serum MMP-2 and MMP-9 in patients with acute myocardial infarction before and after PCI.]
Myocardial Reperfusion Injury
Role of Metalloproteinases and Tissue Inhibitors of Metalloproteinases During Cardiopulmonary Bypass in Rats.
Myocardial Stunning
Duration of ischaemia determines matrix metalloproteinase-2 activation in the reperfused rabbit heart.
Myocarditis
Carvedilol Inhibits Matrix Metalloproteinase-2 Activation in Experimental Autoimmune Myocarditis: Possibilities of Cardioprotective Application.
Myocarditis
Increased activities of cardiac matrix metalloproteinases matrix metalloproteinase (MMP)-2 and MMP-9 are associated with mortality during the acute phase of experimental Trypanosoma cruzi infection.
Myocarditis
Matrix metalloproteinase (MMP)-9, but not MMP-2, is involved in the development and progression of C protein-induced myocarditis and subsequent dilated cardiomyopathy.
Myocarditis
Reduced degradation of the chemokine MCP-3 by matrix metalloproteinase-2 exacerbates myocardial inflammation in experimental viral cardiomyopathy.
Myocarditis
[Experimental study of MMP-2 inhibitor treatment of experimental autoimmune myocarditis in Lewis rats].
Myoma
Effects of ionizing radiation and HPSE1 inhibition on the invasion of oral tongue carcinoma cells on human extracellular matrices in vitro.
Myoma
Extracellular matrix metalloproteinase inducer and matrix metalloproteinase-2 overexpression is associated with loss of hormone receptor expression and poor prognosis in endometrial cancer.
Myoma
In vivo mechanisms of uterine myoma volume reduction with ulipristal acetate treatment.
Myoma
Matrix metalloproteinase activity correlates with uterine myoma volume reduction after ulipristal acetate treatment.
Myopathy, Central Core
Mutations in two matrix metalloproteinase genes, MMP-2 and MT1-MMP, are synthetic lethal in mice.
Myopia
Assessment of the association of matrix metalloproteinases with myopia, refractive error and ocular biometric measures in an Australian cohort.
Myopia
Association between MMP/TIMP Levels in the Aqueous Humor and Plasma with Axial Lengths in Myopia Patients.
Myopia
Cause and Effect Relationship between Changes in Scleral Matrix Metallopeptidase-2 Expression and Myopia Development in Mice.
Myopia
Changes in scleral MMP-2, TIMP-2 and TGFbeta-2 mRNA expression after imposed myopic and hyperopic defocus in chickens.
Myopia
Changes of TGF-?2, MMP-2, and TIMP-2 levels in the vitreous of patients with high myopia.
Myopia
DNA methylation and mRNA expression of IGF-1 and MMP-2 after form-deprivation myopia in guinea pigs.
Myopia
Effects of hepatocyte growth factor on MMP-2 expression in scleral fibroblasts from a guinea pig myopia model.
Myopia
Effects of lumican expression on the apoptosis of scleral fibroblasts: In vivo and in vitro experiments.
Myopia
Expression and cDNA sequence of matrix metalloproteinase-2 (MMP-2) in a mammalian model of human disease processes: Tupaia belangeri.
Myopia
Form-deprivation myopia induces activation of scleral matrix metalloproteinase-2 in tree shrew.
Myopia
Gelatinase A and TIMP-2 expression in the fibrous sclera of myopic and recovering chick eyes.
Myopia
Genipin inhibits the scleral expression of miR-29 and MMP2 and promotes COL1A1 expression in myopic eyes of guinea pigs.
Myopia
Human aqueous humor levels of transforming growth factor-?2: Association with matrix metalloproteinases/tissue inhibitors of matrix metalloproteinases.
Myopia
MMP-2 participates in the sclera of guinea pig with form-deprivation myopia via IGF-1/STAT3 pathway.
Myopia
MMP-2, MMP-3, TIMP-1, TIMP-2, and TIMP-3 protein levels in human aqueous humor: relationship with axial length.
Myopia
Oral Bovine Milk Lactoferrin Administration Suppressed Myopia Development through Matrix Metalloproteinase 2 in a Mouse Model.
Myopia
Pirenzepine Inhibits Myopia in Guinea Pig Model by Regulating the Balance of MMP-2 and TIMP-2 Expression and Increased Tyrosine Hydroxylase Levels.
Myopia
Reduced Scleral TIMP-2 Expression Is Associated With Myopia Development: TIMP-2 Supplementation Stabilizes Scleral Biomarkers of Myopia and Limits Myopia Development.
Myopia
Regulation of Matrix Metalloproteinase-2 Secretion from Scleral Fibroblasts and Retinal Pigment Epithelial Cells by miR-29a.
Myopia
Systematic investigation of the relationship between high myopia and polymorphisms of the MMP2, TIMP2 and TIMP3 genes by a DNA pooling approach.
Myopia
The expression of cytokines in aqueous humor of high myopic patients with cataracts.
Myopia
Up-Regulation of Matrix Metalloproteinase-2 by Scleral Monocyte-Derived Macrophages Contributes to Myopia Development.
Myopia
[Dynamic changes of MMP-2 activity in the posterior sclera of chicks with form-deprivation myopia]
Myopia
[Effect of pirenzepine on form deprivation myopia in chicks and its possible mechanism]
Myopia
[Expressions of collagen , matrix metalloproeinases-2, and tissue inhibitor of matrix metalloproteinase-2 in the posterior sclera of newborn guinea pigs with negative lens-defocused myopia]
Myopia
[Matrix metalloproteinase-2 mRNA expression in the posterior sclera of chick form-deprivation myopia]
Myositis
Matrix metalloproteinases in inflammatory myopathies: enhanced immunoreactivity near atrophic myofibers.
Myxoma
Expression of MMP-2 and MMP-9 in odontogenic myxoma in a child: report of a clinical case.
Myxoma
Immunohistochemical expression of matrix metalloproteinases 1, 2, and 9 in odontogenic myxoma and dental germ papilla.
Myxoma
The expression of apoptotic proteins and matrix metalloproteinases in odontogenic myxomas.
Nasal Polyps
Double-stranded RNA poly(I:C) enhances matrix metalloproteinase mRNA expression in human nasal polyp epithelial cells.
Nasal Polyps
Eosinophil inflammation of nasal polyp tissue: relationships with matrix metalloproteinases, tissue inhibitor of metalloproteinase-1, and transforming growth factor-beta1.
Nasal Polyps
Expression of matrix metalloproteinase 2 and 9 and tissue inhibitor of metalloproteinase 1 in nonrecurrent vs recurrent nasal polyps.
Nasal Polyps
Expression of matrix metalloproteinase-2 and matrix metalloproteinase-9 in recurrent chronic rhinosinusitis with nasal polyposis.
Nasal Polyps
Expression of Matrix Metalloproteinases and Their Tissue Inhibitors in Chronic Rhinosinusitis With Nasal Polyps: Etiopathogenesis and Recurrence.
Nasal Polyps
Involvement of the extracellular matrix proteins periostin and tenascin C in nasal polyp remodeling by regulating the expression of MMPs.
Nasal Polyps
Matrix metalloproteinases and their impact on sinusal extension in chronic rhinosinusitis with nasal polyps.
Nasal Polyps
Nonasthmatic nasal polyposis patients with allergy exhibit greater epithelial MMP positivity.
Nasal Polyps
Polymorphisms in chronic rhinosinusitis with nasal polyps - a systematic review.
Nasal Polyps
Relationship between matrix metalloproteinases MMP-2, MMP-9, tissue inhibitor of matrix metalloproteinases-1 and IL-5, IL-8 in nasal polyps.
Nasal Polyps
Rhinovirus upregulates matrix metalloproteinase-2, matrix metalloproteinase-9, and vascular endothelial growth factor expression in nasal polyp fibroblasts.
Nasal Polyps
Suppression of matrix metalloproteinase production from nasal fibroblasts by fluticasone propionate in vitro.
Nasal Polyps
The role of MMP-2, MMP-9, and TIMP-1 in the pathogenesis of nasal polyps: Immunohistochemical assessment at eight different levels in the epithelial, subepithelial, and deep layers of the mucosa.
Nasal Polyps
Vitamin D decreases the secretion of matrix metalloproteinase-2 and matrix metalloproteinase-9 in fibroblasts derived from Taiwanese patients with chronic rhinosinusitis with nasal polyposis.
Nasal Polyps
[Effects of double-stranded RNA poly(I:C) on matrix metalloproteinase mRNA expression in human nasal polyp epithelial cells]
Nasopharyngeal Carcinoma
A single nucleotide polymorphism in the matrix metalloproteinase 2 promoter is closely associated with high risk of nasopharyngeal carcinoma in Cantonese from southern China.
Nasopharyngeal Carcinoma
Clinicopathologic significance of plasma matrix metalloproteinase-2 and -9 levels in patients with undifferentiated nasopharyngeal carcinoma.
Nasopharyngeal Carcinoma
Correlation between expression of extracellular matrix metalloproteinase inducer and matrix metalloproteinase-2 and cervical lymph node metastasis of nasopharyngeal carcinoma.
Nasopharyngeal Carcinoma
Cyclooxygenase-2 inhibitor celecoxib suppresses invasion and migration of nasopharyngeal carcinoma cell lines through a decrease in matrix metalloproteinase-2 and -9 activity.
Nasopharyngeal Carcinoma
Down-regulation of MMP-2 through the p38 MAPK-NF-kappaB-dependent pathway by aloe-emodin leads to inhibition of nasopharyngeal carcinoma cell invasion.
Nasopharyngeal Carcinoma
Effect of WNT5A on epithelial-mesenchymal transition and its correlation with tumor invasion and metastasis in nasopharyngeal carcinoma.
Nasopharyngeal Carcinoma
Epigallocatechin-3-gallate inhibits migration of human nasopharyngeal carcinoma cells by repressing MMP-2 expression.
Nasopharyngeal Carcinoma
Evodiamine inhibits the migration and invasion of nasopharyngeal carcinoma cells in vitro via repressing MMP-2 expression.
Nasopharyngeal Carcinoma
IL-6/NOS2 inflammatory signals regulate MMP-9 and MMP-2 activity and disease outcome in nasopharyngeal carcinoma patients.
Nasopharyngeal Carcinoma
Interleukin-6 promotes the migration and invasion of nasopharyngeal carcinoma cell lines and upregulates the expression of MMP-2 and MMP-9.
Nasopharyngeal Carcinoma
Matrix metalloproteinase 2 contributes to aggressive phenotype, epithelial-mesenchymal transition and poor outcome in nasopharyngeal carcinoma.
Nasopharyngeal Carcinoma
Morusin Suppresses Cancer Cell Invasion and MMP-2 Expression through ERK Signaling in Human Nasopharyngeal Carcinoma.
Nasopharyngeal Carcinoma
Nobiletin inhibits invasion and migration of human nasopharyngeal carcinoma cell lines by involving ERK1/2 and transcriptional inhibition of MMP-2.
Nasopharyngeal Carcinoma
Norepinephrine up-regulates the expression of vascular endothelial growth factor, matrix metalloproteinase (MMP)-2, and MMP-9 in nasopharyngeal carcinoma tumor cells.
Nasopharyngeal Carcinoma
Pinostilbene Hydrate Inhibits the Migration and Invasion of Human Nasopharyngeal Carcinoma Cells by Downregulating MMP-2 Expression and Suppressing Epithelial-Mesenchymal Transition Through the Mitogen-Activated Protein Kinase Signaling Pathways.
Nasopharyngeal Carcinoma
Regulation of matrix metalloproteinase-1 by Epstein-Barr virus proteins.
Nasopharyngeal Carcinoma
Rubus idaeus Inhibits Migration and Invasion of Human Nasopharyngeal Carcinoma Cells by Suppression of MMP-2 through Modulation of the ERK1/2 Pathway.
Nasopharyngeal Carcinoma
Salvianolic acid A suppresses MMP-2 expression and restrains cancer cell invasion through ERK signaling in human nasopharyngeal carcinoma.
Nasopharyngeal Carcinoma
The association between gene polymorphisms and risk of nasopharyngeal carcinoma.
Nasopharyngeal Carcinoma
Tissue inhibitor of matrix metalloproteinase-2 in nasopharyngeal carcinoma.
Nasopharyngeal Carcinoma
Use of nimotuzumab combined with cisplatin in treatment of nasopharyngeal carcinoma and its effect on expressions of VEGF and MMP-2.
Nasopharyngeal Carcinoma
Vascular endothelial growth factor165-regulated nasopharyngeal carcinoma cell lines invasion and migration involve expression and activation of matrix metalloproteinase-2.
Nasopharyngeal Carcinoma
Zoledronic acid inhibits proliferation and impairs migration and invasion through downregulating VEGF and MMPs expression in human nasopharyngeal carcinoma cells.
Nasopharyngeal Carcinoma
[Effect of macrophage migration inhibitory factor (MIF) on expression of MMP-2,MMP-9,and IL-8 in nasopharyngeal carcinoma cell strains]
Nasopharyngeal Carcinoma
[Expressions of COX-2 and MMP-2 in nasopharyngeal carcinoma and the their relationship with lymph node metastasis]
Nasopharyngeal Neoplasms
Contribution of Matrix Metalloproteinase-2 Promoter Genotypes to Nasopharyngeal Cancer Susceptibility and Metastasis in Taiwan.
Nasopharyngeal Neoplasms
Dione-thiophene conjugate inhibits proliferation and metastasis of nasopharyngeal carcinoma cells through calcium binding protein-P down-regulation.
Neoplasm Metastasis
'Increased expression of seprase, a membrane-type serine protease, is associated with lymph node metastasis in human colorectal cancer'.
Neoplasm Metastasis
(-)-Epigallocatechin gallate inhibits membrane-type 1 matrix metalloproteinase, MT1-MMP, and tumor angiogenesis.
Neoplasm Metastasis
(-)-Epigallocatechin-3-gallate promotes pro-matrix metalloproteinase-7 production via activation of the JNK1/2 pathway in HT-29 human colorectal cancer cells.
Neoplasm Metastasis
(-)-Kusunokinin inhibits breast cancer in N-nitrosomethylurea-induced mammary tumor rats.
Neoplasm Metastasis
(-)-Oleocanthal inhibits growth and metastasis by blocking activation of STAT3 in human hepatocellular carcinoma.
Neoplasm Metastasis
(2-Aminobenzothiazole)-Methyl-1,1-Bisphosphonic Acids: Targeting Matrix Metalloproteinase 13 Inhibition to the Bone.
Neoplasm Metastasis
(±)Equol inhibits invasion in prostate cancer DU145 cells possibly via down-regulation of matrix metalloproteinase-9, matrix metalloproteinase-2 and urokinase-type plasminogen activator by antioxidant activity.
Neoplasm Metastasis
2-Dodecyl-6-methoxycyclohexa-2,5-diene-1,4-dione inhibits the growth and metastasis of breast carcinoma in mice.
Neoplasm Metastasis
3,4-Dihydroxybenzalactone Suppresses Human Non-Small Cell Lung Carcinoma Cells Metastasis via Suppression of Epithelial to Mesenchymal Transition, ROS-Mediated PI3K/AKT/MAPK/MMP and NF?B Signaling Pathways.
Neoplasm Metastasis
3,5-Dicaffeoyl-epi-quinic acid inhibits the PMA-stimulated activation and expression of MMP-9 but not MMP-2 via downregulation of MAPK pathway.
Neoplasm Metastasis
?-Elemene inhibits the metastasis of B16F10 melanoma cells by downregulation of the expression of uPA, uPAR, MMP-2, and MMP-9.
Neoplasm Metastasis
?-Mangostin suppresses lipopolysaccharide-induced invasion by inhibiting matrix metalloproteinase-2/9 and increasing E-cadherin expression through extracellular signal-regulated kinase signaling in pancreatic cancer cells.
Neoplasm Metastasis
A chimera of green fluorescent protein with gelatinase binding and tumor targeting peptide.
Neoplasm Metastasis
A comparison of ocular melanocyte and uveal melanoma cell invasion and the implication of alpha1beta1, alpha4beta1 and alpha6beta1 integrins.
Neoplasm Metastasis
A dual-functional magnetic microsphere for ICP-MS quantification and fluorescence imaging of matrix metalloproteinase 2 in cell secretion.
Neoplasm Metastasis
A functional polymorphism in the matrix metalloproteinase-2 gene promoter (-1306C/T) is associated with risk of development but not metastasis of gastric cardia adenocarcinoma.
Neoplasm Metastasis
A high serum matrix metalloproteinase-2 level is associated with an adverse prognosis in node-positive breast carcinoma.
Neoplasm Metastasis
A matrix metalloproteinase expressed on the surface of invasive tumour cells.
Neoplasm Metastasis
A Multi-functional Vector for delivery of Genome Editing Plasmid Targeting ?-Catenin to Re-modulate Cancer Cell Properties.
Neoplasm Metastasis
A multiplicity of anti-invasive effects of farnesyl transferase inhibitor SCH66336 in human head and neck cancer.
Neoplasm Metastasis
A novel bisindole-PBD conjugate inhibits angiogenesis by regulating STAT3 and VEGF in breast cancer cells.
Neoplasm Metastasis
A novel function of syndecan-2, suppression of matrix metalloproteinase-2 activation, which causes suppression of metastasis.
Neoplasm Metastasis
A Novel Synthetic Compound (E)-5-((4-oxo-4H-chromen-3-yl)methyleneamino)-1-phenyl-1H-pyrazole-4-carbonitrile Inhibits TNF?-Induced MMP9 Expression via EGR-1 Downregulation in MDA-MB-231 Human Breast Cancer Cells.
Neoplasm Metastasis
A novel tripeptide, tyroserleutide, inhibits irradiation-induced invasiveness and metastasis of hepatocellular carcinoma in nude mice.
Neoplasm Metastasis
A nutrient mixture inhibits glioblastoma xenograft U-87 MG growth in male nude mice.
Neoplasm Metastasis
A plasma membrane-associated component of ovarian adenocarcinoma cells enhances the catalytic efficiency of matrix metalloproteinase-2.
Neoplasm Metastasis
A randomized, phase II trial of ketoconazole plus alendronate versus ketoconazole alone in patients with androgen independent prostate cancer and bone metastases.
Neoplasm Metastasis
A role for PI3K-Akt signaling in pulmonary metastatic nodule formation of the osteosarcoma cell line, LM8.
Neoplasm Metastasis
A single nucleotide polymorphism in the MMP-9 promoter affects tumor progression and invasive phenotype of gastric cancer.
Neoplasm Metastasis
Accelerated orthotopic hepatocellular carcinomas growth is linked to increased expression of pro-angiogenic and prometastatic factors in murine liver fibrosis.
Neoplasm Metastasis
Accumulation of extracellular matrix in the liver induces high metastatic potential of hepatocellular carcinoma to the lung.
Neoplasm Metastasis
Acidic extracellular pH promotes experimental metastasis of human melanoma cells in athymic nude mice.
Neoplasm Metastasis
Actin cytoskeleton participation in the onset of IL-1beta induction of an invasive mesenchymal-like phenotype in epithelial MCF-7 cells.
Neoplasm Metastasis
Actinidia callosa var. callosa suppresses metastatic potential of human hepatoma cell SK-Hep1 by inhibiting matrix metalloproteinase-2 through PI3K/Akt and MAPK signaling pathways.
Neoplasm Metastasis
Activated leukocyte cell adhesion molecule (ALCAM/CD166/MEMD), a novel actor in invasive growth, controls matrix metalloproteinase activity.
Neoplasm Metastasis
Activated matrix metalloproteinase-2--a potential marker of prognosis for epithelial ovarian cancer.
Neoplasm Metastasis
Activation of matrix metalloproteinase-2 (MMP-2) by membrane type 1 matrix metalloproteinase through an artificial receptor for proMMP-2 generates active MMP-2.
Neoplasm Metastasis
Activation of MMP-2 and MMP-9 in patients with oral squamous cell carcinoma.
Neoplasm Metastasis
Activation of the precursor of gelatinase A/72 kDa type IV collagenase/MMP-2 in lung carcinomas correlates with the expression of membrane-type matrix metalloproteinase (MT-MMP) and with lymph node metastasis.
Neoplasm Metastasis
Activation of tumor cell proliferation by thyroid hormone in a mouse model of follicular thyroid carcinoma.
Neoplasm Metastasis
Active and inactive forms of matrix metalloproteinases 2 and 9 in cutaneous melanoma.
Neoplasm Metastasis
Activity and expression of urokinase-type plasminogen activator and matrix metalloproteinases in human colorectal cancer.
Neoplasm Metastasis
Activity of matrix metalloproteinase-2 (MMP-2) in canine oronasal tumors.
Neoplasm Metastasis
Activity of type IV collagenases (MMP-2 and MMP-9) in primary pulmonary carcinomas: a quantitative analysis.
Neoplasm Metastasis
Ad.mda-7 (IL-24) selectively induces apoptosis in hepatocellular carcinoma cell lines, suppresses metastasis, and enhances the effect of doxorubicin on xenograft tumors.
Neoplasm Metastasis
Adaptation to chronic acidic extracellular pH elicits a sustained increase in lung cancer cell invasion and metastasis.
Neoplasm Metastasis
Adenovirus-mediated small interfering RNA against matrix metalloproteinase-2 suppresses tumor growth and lung metastasis in mice.
Neoplasm Metastasis
Alpha-chaconine-reduced metastasis involves a PI3K/Akt signaling pathway with downregulation of NF-kappaB in human lung adenocarcinoma A549 cells.
Neoplasm Metastasis
alpha-Lipoic acid reduces matrix metalloproteinase activity in MDA-MB-231 human breast cancer cells.
Neoplasm Metastasis
Alpha-mangostin suppresses PC-3 human prostate carcinoma cell metastasis by inhibiting matrix metalloproteinase-2/9 and urokinase-plasminogen expression through the JNK signaling pathway.
Neoplasm Metastasis
Alterations in enhancer of zeste homolog 2, matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 expression are associated with ex vivo and in vitro bone metastasis in renal cell carcinoma.
Neoplasm Metastasis
Alterations of metastasis-related genes identified using an oligonucleotide microarray of genistein-treated HCC1395 breast cancer cells.
Neoplasm Metastasis
Altered expression of metastasis-associated and regulatory molecules in effusions from breast cancer patients: a novel model for tumor progression.
Neoplasm Metastasis
Aluminum naphthalocyanine conjugate as an MMP-2-activatable photoacoustic probe for in vivo tumor imaging.
Neoplasm Metastasis
Amentoflavone Inhibits Experimental Tumor Metastasis Through a Regulatory Mechanism Involving MMP-2, MMP-9, Prolyl Hydroxylase, Lysyl Oxidase, VEGF, ERK-1, ERK-2, STAT-1, nm23 and Cytokines in Lung Tissues of C57BL/6 Mice.
Neoplasm Metastasis
Amplification of MMP-2 and MMP-9 production by prostate cancer cell lines via activation of protease-activated receptors.
Neoplasm Metastasis
An essential role for N-cadherin and beta-catenin for progression in tongue squamous cell carcinoma and their effect on invasion and metastasis of Tca8113 tongue cancer cells.
Neoplasm Metastasis
An in vivo model for screening peptidomimetic inhibitors of gelatinase A.
Neoplasm Metastasis
An inverse relationship between KAI1 expression, invasive ability, and MMP-2 expression and activity in bladder cancer cell lines.
Neoplasm Metastasis
An osteoblast-derived proteinase controls tumor cell survival via TGF-beta activation in the bone microenvironment.
Neoplasm Metastasis
Analysis of expression of matrix metalloproteinases-2 and -9 in hypopharyngeal squamous cell carcinoma by in situ hybridization.
Neoplasm Metastasis
Analysis of matrix metalloproteinase mRNAs expressed in hepatocellular carcinoma cell lines.
Neoplasm Metastasis
Angiotensin receptor blocker Losartan inhibits tumor growth of colorectal cancer.
Neoplasm Metastasis
Anthocyanins from Black Rice (Oryza sativa L.) Demonstrate Antimetastatic Properties by Reducing MMPs and NF-?B Expressions in Human Oral Cancer CAL 27 Cells.
Neoplasm Metastasis
Anti-cancer effect of metformin on the metastasis and invasion of primary breast cancer cells through mediating NF-kB activity.
Neoplasm Metastasis
Anti-endometriosis Mechanism of Jiawei Foshou San Based on Network Pharmacology.
Neoplasm Metastasis
Anti-inflammatory and anticancer effects of p-methoxycinnamic acid, an active phenylpropanoid, against 1,2-dimethylhydrazine-induced rat colon carcinogenesis.
Neoplasm Metastasis
Anti-Metastatic Effects of Antrodan with and without Cisplatin on Lewis Lung Carcinomas in a Mouse Xenograft Model.
Neoplasm Metastasis
Anticancer activity of halofuginone in a preclinical model of osteosarcoma: inhibition of tumor growth and lung metastases.
Neoplasm Metastasis
Anticancer effects of tanshinone I in human non-small cell lung cancer.
Neoplasm Metastasis
Anticancer Effects of Valproic Acid via Regulation of Epigenetic Mechanisms in Non-small-cell Lung Cancer A549 Cell Line.
Neoplasm Metastasis
Anticancer mechanisms of YC-1 in human lung cancer cell line, NCI-H226.
Neoplasm Metastasis
Antimetastatic and anti-invasive ability of phospho-ascorbyl palmitate through intracellular ascorbate enrichment and the resultant antioxidant action.
Neoplasm Metastasis
Antimetastatic effects of Eclipta prostrata extract on oral cancer cells.
Neoplasm Metastasis
Antimetastatic Potentials of Phyllanthusurinaria L on A549 and Lewis Lung Carcinoma Cells via Repression of Matrix-Degrading Proteases.
Neoplasm Metastasis
Antineoplastic activity of Newcastle disease virus strain D90 in oral squamous cell carcinoma.
Neoplasm Metastasis
Antineoplastic effect of intracellular expression of a single-chain antibody directed against type IV collagenase.
Neoplasm Metastasis
Antitumor activity of anti-type IV collagenase monoclonal antibody and its lidamycin conjugate against colon carcinoma.
Neoplasm Metastasis
Antitumor and radiosensitizing synergistic effects of apigenin and cryptotanshinone against solid Ehrlich carcinoma in female mice.
Neoplasm Metastasis
Antitumor effects of the molecule-downsized immunoconjugate composed of lidamycin and Fab' fragment of monoclonal antibody directed against type IV collagenase.
Neoplasm Metastasis
Antitumor effects of the novel quinazolinone MJ-33: Inhibition of metastasis through the MAPK, AKT, NF-?B and AP-1 signaling pathways in DU145 human prostate cancer cells.
Neoplasm Metastasis
Antitumor efficacy of Kisspeptin in human malignant mesothelioma cells.
Neoplasm Metastasis
Antitumor efficacy of reticulol from Streptoverticillium against the lung metastasis model B16F10 melanoma. Lung metastasis inhibition by growth inhibition of melanoma.
Neoplasm Metastasis
Antitumor evaluation of carboxymethyl chitosan based norcantharidin conjugates against gastric cancer as novel polymer therapeutics.
Neoplasm Metastasis
Apigenin Attenuates Insulin-Like Growth Factor-I Signaling in an Autochthonous Mouse Prostate Cancer Model.
Neoplasm Metastasis
Apoptotic Induction and Anti-Migratory Effects of Rhazya Stricta Fruit Extracts on a Human Breast Cancer Cell Line.
Neoplasm Metastasis
Aquaporin 1 promotes the proliferation and migration of lung cancer cell in vitro.
Neoplasm Metastasis
Arylamino methylene bisphosphonate derivatives as bone seeking matrix metalloproteinase inhibitors.
Neoplasm Metastasis
Assay of matrix metalloproteinases types 1, 2, 3 and 9 in breast cancer.
Neoplasm Metastasis
Assessment of indirect hemagglutination and zymography procedures in evaluation of gelatinase a in patients with benign and malignant prostate hyperplasia.
Neoplasm Metastasis
Association between cyclooxygenase-2 and matrix metalloproteinase-2 expression in non-small cell lung cancer.
Neoplasm Metastasis
Association between Expression of Tissue Inhibitors of Metalloproteinases-1, Matrix Metalloproteinase-2, and Matrix Metalloproteinase-9 Genes and Axillary Lymph Nodes Metastasis in Patients with Breast Cancer.
Neoplasm Metastasis
Association of cyclooxygenase-2 and matrix metalloproteinase-2 expression in human breast cancer.
Neoplasm Metastasis
Association of matrix metalloproteinase (MMP)-2 and -9 expression with extra-gastrointestinal stromal tumor metastasis.
Neoplasm Metastasis
Association of matrix metalloproteinase-2 and -9 promoter polymorphisms with colorectal cancer in Chinese.
Neoplasm Metastasis
Association of MMP-2 activation potential with metastatic progression in human breast cancer cell lines independent of MMP-2 production.
Neoplasm Metastasis
Association of MMP-2 expression and prognosis in osteosarcoma patients.
Neoplasm Metastasis
Association of single nucleotide polymorphisms of ?2-adrenergic receptor gene with clinicopathological features of pancreatic carcinoma.
Neoplasm Metastasis
Astragaloside IV increases MMP-2 mRNA and protein expression in human lung cancer A549 cells.
Neoplasm Metastasis
Astragaloside IV inhibits cell invasion and metastasis in vulvar squamous cell carcinoma through the TGF-?1/FAK/AKT signaling pathway.
Neoplasm Metastasis
Astrocytes directly influence tumor cell invasion and metastasis in vivo.
Neoplasm Metastasis
Bacoside A downregulates matrix metalloproteinases 2 and 9 in DEN-induced hepatocellular carcinoma.
Neoplasm Metastasis
Baicalin Suppresses Migration, Invasion and Metastasis of Breast Cancer via p38MAPK Signaling Pathway.
Neoplasm Metastasis
Balance between activation and inhibition of matrix metalloproteinase-2 (MMP-2) is altered in colorectal tumors compared to normal colonic epithelium.
Neoplasm Metastasis
Bcl-2 promotes invasion and lung metastasis by inducing matrix metalloproteinase-2.
Neoplasm Metastasis
Benzyl isothiocyanate (BITC) inhibits migration and invasion of human colon cancer HT29 cells by inhibiting matrix metalloproteinase-2/-9 and urokinase plasminogen (uPA) through PKC and MAPK signaling pathway.
Neoplasm Metastasis
Benzyl isothiocyanate suppresses pancreatic tumor angiogenesis and invasion by inhibiting HIF-?/VEGF/Rho-GTPases: pivotal role of STAT-3.
Neoplasm Metastasis
Betulinic acid induces apoptosis and suppresses metastasis in hepatocellular carcinoma cell lines in vitro and in vivo.
Neoplasm Metastasis
Binding affinities for sulfonamide inhibitors with matrix metalloproteinase-2 using a linear response method.
Neoplasm Metastasis
Biological evaluation of optically pure chiral binuclear copper(ii) complexes based on a rosin derivative as highly potential anticancer agents.
Neoplasm Metastasis
Biphenyl substituted lysine derivatives as recognition elements for the matrix metalloproteinases MMP-2 and MMP-9.
Neoplasm Metastasis
Blockade of vascular angiogenesis by Aspergillus usamii var. shirousamii-transformed Angelicae Gigantis Radix and Zizyphus jujuba.
Neoplasm Metastasis
Blockage of Squamous Cancer Cell Collective Invasion by FAK Inhibition Is Released by CAFs and MMP-2.
Neoplasm Metastasis
BMP2 induces PANC-1 cell invasion by MMP-2 overexpression through ROS and ERK.
Neoplasm Metastasis
Bone sialoprotein does not interact with pro-gelatinase A (MMP-2) or mediate MMP-2 activation.
Neoplasm Metastasis
Bornyl cis-4-Hydroxycinnamate Suppresses Cell Metastasis of Melanoma through FAK/PI3K/Akt/mTOR and MAPK Signaling Pathways and Inhibition of the Epithelial-to-Mesenchymal Transition.
Neoplasm Metastasis
BRD4 promotes metastatic potential in oral squamous cell carcinoma through the epigenetic regulation of the MMP2 gene.
Neoplasm Metastasis
Breast Cancer Recurrence Risk Assessment: Is Non-Invasive Monitoring an Option?
Neoplasm Metastasis
Brucine suppresses breast cancer metastasis via inhibiting epithelial mesenchymal transition and matrix metalloproteinases expressions.
Neoplasm Metastasis
Brucine, an alkaloid from seeds of Strychnos nux-vomica Linn., represses hepatocellular carcinoma cell migration and metastasis: The role of hypoxia inducible factor 1 pathway.
Neoplasm Metastasis
C-C chemokine receptor 5 on pulmonary fibrocytes facilitates migration and promotes metastasis via matrix metalloproteinase 9.
Neoplasm Metastasis
Caffeic Acid phenethyl ester inhibits oral cancer cell metastasis by regulating matrix metalloproteinase-2 and the mitogen-activated protein kinase pathway.
Neoplasm Metastasis
Caffeoyl pyrrolidine derivative LY52 inhibits tumor invasion and metastasis via suppression of matrix metalloproteinase activity.
Neoplasm Metastasis
Cambodian Phellinus linteus inhibits experimental metastasis of melanoma cells in mice via regulation of urokinase type plasminogen activator.
Neoplasm Metastasis
Cancer cell-associated fibronectin induces release of matrix metalloproteinase-2 from normal fibroblasts.
Neoplasm Metastasis
Capn4 contributes to tumour growth and metastasis of hepatocellular carcinoma by activation of the FAK-Src signalling pathways.
Neoplasm Metastasis
Catalyser-21(TM), a mineral water derived from leaf soil, inhibits tumor cell invasion and angiogenesis.
Neoplasm Metastasis
CD147 and matrix-metalloproteinase-2 expression in metastatic and non-metastatic uveal melanomas.
Neoplasm Metastasis
Cell membrane-associated MT1-MMP dependent activation of MMP-2 in SiHa (human cervical cancer) cells.
Neoplasm Metastasis
Cell-based identification of natural substrates and cleavage sites for extracellular proteases by SILAC proteomics.
Neoplasm Metastasis
Changes to N-linked oligosaccharide chains of human serum immunoglobulin G and matrix metalloproteinase-2 with cancer progression.
Neoplasm Metastasis
Characterization of protease expression in human prostate-cancer cell-lines.
Neoplasm Metastasis
Chemical composition and pharmacological bio-efficacy of Parrotiopsis jacquemontiana (Decne) Rehder for anticancer activity.
Neoplasm Metastasis
Chemoinhibitory effect of mulberry anthocyanins on melanoma metastasis involved in the Ras/PI3K pathway.
Neoplasm Metastasis
Chitooligosaccharides inhibit activation and expression of matrix metalloproteinase-2 in human dermal fibroblasts.
Neoplasm Metastasis
Chromodomain Helicase/ATPase DNA-Binding Protein 1-Like Gene (CHD1L) Expression and Implications for Invasion and Metastasis of Breast Cancer.
Neoplasm Metastasis
Circulating tumor cells and serum levels of MMP-2, MMP-9 and VEGF as markers of the metastatic process in patients with high risk of metastatic progression.
Neoplasm Metastasis
CK2 inhibitor CX4945 induces sequential inactivation of proteins in the signaling pathways related with cell migration and suppresses metastasis of A549 human lung cancer cells.
Neoplasm Metastasis
Clinical Relevance of Increased Endothelial and Mesothelial Expression of Proangiogenic Proteases and VEGFA in the Omentum of Patients with Metastatic Ovarian High-Grade Serous Carcinoma.
Neoplasm Metastasis
Clinical relevance of serum levels of matrix metallopeptidase-2, and tissue inhibitor of metalloproteinase-1 and -2 in patients with malignant melanoma.
Neoplasm Metastasis
Clinical significance of expression of membrane type 1 matrix metalloproteinase and matrix metalloproteinase-2 in human head and neck squamous cell carcinoma.
Neoplasm Metastasis
Clinical significance of matrix metalloproteinase 2 and 9 in breast cancer.
Neoplasm Metastasis
Clinical significance of matrix metalloproteinase-2 in cancer of uterine cervix: a semiquantitative study of immunoreactivities using tissue array.
Neoplasm Metastasis
Clinical significance of matrix metalloproteinase-2 in endometrial cancer: A systematic review and meta-analysis.
Neoplasm Metastasis
Clinical significance of plasma MMP-2 and MMP-9 levels as biomarkers for tumor expression in breast cancer patients in Egypt.
Neoplasm Metastasis
Clinicopathologic and Prognostic Significance of Gelatinase A in Tunisian Colorectal Cancer: A Case-Control Study.
Neoplasm Metastasis
Clinicopathologic evaluation of immunohistochemical CD147 and MMP-2 expression in differentiated thyroid carcinoma.
Neoplasm Metastasis
Clinicopathological and biological significance of human voltage-gated proton channel Hv1 over-expression in breast cancer.
Neoplasm Metastasis
Clinicopathological characteristics of carcinoma from unknown primary in cervical lymph nodes.
Neoplasm Metastasis
Clinicopathological significance of E-cadherin, VEGF, and MMPs in gastric cancer.
Neoplasm Metastasis
Clinicopathological significance of matrix metalloproteinase 2 protein expression in patients with renal cell carcinoma: A case-control study and meta-analysis.
Neoplasm Metastasis
Clinicopathological Significance of Matrix Metalloproteinase-2 Protein Expression in Renal Cell Carcinoma Patients.
Neoplasm Metastasis
Clinicopathological significance of the gene expression of matrix metalloproteinases and reversion-inducing cysteine-rich protein with Kazal motifs in patients with colorectal cancer: MMP-2 gene expression is a useful predictor of liver metastasis from colorectal cancer.
Neoplasm Metastasis
Clusterin Silencing in Prostate Cancer Induces Matrix Metalloproteinases by an NF-?B-Dependent Mechanism.
Neoplasm Metastasis
Co-delivery of autophagy inhibitor and gemcitabine using a pH-activatable core-shell nanobomb inhibits pancreatic cancer progression and metastasis.
Neoplasm Metastasis
Coexpression of integrin alpha(v)beta3 and matrix metalloproteinase-2 (MMP-2) coincides with MMP-2 activation: correlation with melanoma progression.
Neoplasm Metastasis
Coexpression of vimentin and keratins by human melanoma tumor cells: correlation with invasive and metastatic potential.
Neoplasm Metastasis
Collagenase is expressed by rabbit VX2 tumour cells in syngeneic and xenogeneic hosts.
Neoplasm Metastasis
Combination of ACY-241 and JQ1 Synergistically Suppresses Metastasis of HNSCC via Regulation of MMP-2 and MMP-9.
Neoplasm Metastasis
Combination of metformin and 5-aminosalicylic acid cooperates to decrease proliferation and induce apoptosis in colorectal cancer cell lines.
Neoplasm Metastasis
Combination of nadroparin with radiotherapy results in powerful synergistic antitumor effects in lung adenocarcinoma A549 cells.
Neoplasm Metastasis
Combination therapy including a gelatinase inhibitor and cytotoxic agent reduces local invasion and metastasis of murine Lewis lung carcinoma.
Neoplasm Metastasis
Combinatorial interactions of p53, activating protein-2, and YB-1 with a single enhancer element regulate gelatinase A expression in neoplastic cells.
Neoplasm Metastasis
Comparative effects of EGCG, green tea and a nutrient mixture on the patterns of MMP-2 and MMP-9 expression in cancer cell lines.
Neoplasm Metastasis
Comparison of matrix metalloproteinase expression between primary tumors with or without liver metastasis in pancreatic and colorectal carcinomas.
Neoplasm Metastasis
Comparison of responsiveness to cancer development and anti-cancer drug in three different C57BL/6N stocks.
Neoplasm Metastasis
Comparison of the prognostic value of matrix metalloproteinases 2 and 9 in cutaneous melanoma.
Neoplasm Metastasis
Concomitant inhibition of epidermal growth factor and vascular endothelial growth factor receptor tyrosine kinases reduces growth and metastasis of human salivary adenoid cystic carcinoma in an orthotopic nude mouse model.
Neoplasm Metastasis
Contribution of Matrix Metalloproteinase-2 Promoter Genotypes to Nasopharyngeal Cancer Susceptibility and Metastasis in Taiwan.
Neoplasm Metastasis
Control of type IV collagenase activity by components of the urokinase-plasmin system: a regulatory mechanism with cell-bound reactants.
Neoplasm Metastasis
Coordinate expression of membrane type-matrix metalloproteinases-2 and 3 (MT2-MMP and MT3-MMP) and matrix metalloproteinase-2 (MMP-2) in primary and metastatic melanoma cells.
Neoplasm Metastasis
Coordinated targeting of MMP-2/MMP-9 by miR-296-3p/FOXCUT exerts tumor-suppressing effects in choroidal malignant melanoma.
Neoplasm Metastasis
Correlation between bone scan findings and collagenase activities in patients with breast cancer.
Neoplasm Metastasis
Correlation between expression of extracellular matrix metalloproteinase inducer and matrix metalloproteinase-2 and cervical lymph node metastasis of nasopharyngeal carcinoma.
Neoplasm Metastasis
Correlation between expression of matrix metalloproteinase-2 (MMP-2), and matrix metalloproteinase-9 (MMP-9) and angiogenesis in colorectal adenocarcinoma.
Neoplasm Metastasis
Correlation between protein expression of PTEN in human pancreatic cancer and the proliferation, infiltration, metastasis and prognosis.
Neoplasm Metastasis
Correlation between vascular endothelial growth factor-C expression and invasion phenotype in cervical carcinomas.
Neoplasm Metastasis
Correlation of matrix metalloproteinase-2, -9, tissue inhibitor-1 of matrix metalloproteinase and CD44 variant 6 in head and neck cancer metastasis.
Neoplasm Metastasis
Correlation of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinase expression in ileal carcinoids, lymph nodes and liver metastasis with prognosis and survival.
Neoplasm Metastasis
Correlation of tumor- and stromal-derived MT1-MMP expression with progression of human ovarian tumors in SCID mice.
Neoplasm Metastasis
Correlations of serum VEGF and MMP-2 levels with CLM in CRC patients and effects of TACE on their expressions.
Neoplasm Metastasis
Corrigendum to "Caffeic Acid Phenethyl Ester Inhibits Oral Cancer Cell Metastasis by Regulating Matrix Metalloproteinase-2 and the Mitogen-Activated Protein Kinase Pathway".
Neoplasm Metastasis
Corrigendum to "Eupatilin inhibits angiogenesis-mediated human hepatocellular metastasis by reducing MMP-2 and VEGF signaling" [Bioorg. Med. Chem. Lett. 28(19) (2018) 3150-3154].
Neoplasm Metastasis
Critical role for matrix metalloproteinase-9 in platelet-activating factor-induced experimental tumor metastasis.
Neoplasm Metastasis
CSE1L, a novel microvesicle membrane protein, mediates Ras-triggered microvesicle generation and metastasis of tumor cells.
Neoplasm Metastasis
Curcumin loaded selenium nanoparticles synergize the anticancer potential of doxorubicin contained in self-assembled, cell receptor targeted nanoparticles.
Neoplasm Metastasis
Curcumin, a potential inhibitor of MMP-2 in human laryngeal squamous carcinoma cells HEp2.
Neoplasm Metastasis
Curcumol inhibits lung adenocarcinoma growth and metastasis via inactivation of PI3K/AKT and Wnt/ß-catenin pathway.
Neoplasm Metastasis
Cutting to the Chase: How Matrix Metalloproteinase-2 Activity Controls Breast-Cancer-to-Bone Metastasis.
Neoplasm Metastasis
CXCL10 accelerates EMT and metastasis by MMP-2 in hepatocellular carcinoma.
Neoplasm Metastasis
Cyclin-dependent kinase 9 is required for tumor necrosis factor-alpha-stimulated matrix metalloproteinase-9 expression in human lung adenocarcinoma cells.
Neoplasm Metastasis
Cyclooxygenase-2 functions as a downstream mediator of lysophosphatidic acid to promote aggressive behavior in ovarian carcinoma cells.
Neoplasm Metastasis
Cyclooxygenase-2 is associated with malignant phenotypes in human lung cancer.
Neoplasm Metastasis
Cyclophosphamide promotes pulmonary metastasis on mouse lung adenocarcinoma.
Neoplasm Metastasis
Cytokines, inducers and inhibitors modulate MMP-2 and MMP?9 secretion by human Fanconi anemia immortalized fibroblasts.
Neoplasm Metastasis
Decreased expression of ARHGAP15 promotes the development of colorectal cancer through PTEN/AKT/FOXO1 axis.
Neoplasm Metastasis
Decreased expression of SERPINB1 correlates with tumor invasion and poor prognosis in hepatocellular carcinoma.
Neoplasm Metastasis
Dehydroandrographolide inhibits oral cancer cell migration and invasion through NF-?B-, AP-1-, and SP-1-modulated matrix metalloproteinase-2 inhibition.
Neoplasm Metastasis
Density-dependent regulation of cell-surface association of matrix metalloproteinase-2 (MMP-2) in breast-carcinoma cells.
Neoplasm Metastasis
Depsipeptide a histone deacetlyase inhibitor down regulates levels of matrix metalloproteinases 2 and 9 mRNA and protein expressions in lung cancer cells (A549).
Neoplasm Metastasis
Des-?-carboxyl prothrombin induces matrix metalloproteinase activity in hepatocellular carcinoma cells by involving the ERK1/2 MAPK signalling pathway.
Neoplasm Metastasis
Design and characterization of a metalloproteinase inhibitor-tethered resin for the detection of active MMPs in biological samples.
Neoplasm Metastasis
Design, synthesis and biological evaluation of a new thieno[2,3-d]pyrimidine-based urea derivative with potential antitumor activity against tamoxifen sensitive and resistant breast cancer cell lines.
Neoplasm Metastasis
Detection and localization of mRNAs encoding matrix metalloproteinases and their tissue inhibitor in human breast pathology.
Neoplasm Metastasis
Detection of endometrial cancer by determination of matrix metalloproteinases in the uterine cavity.
Neoplasm Metastasis
Determination of gelatinase A using a modified indirect hemagglutination assay in human prostate cancer screening and assessment of its correlation with prostate-specific antigen parameters.
Neoplasm Metastasis
Development of a pH-responsive polymersome inducing endoplasmic reticulum stress and autophagy blockade.
Neoplasm Metastasis
Dicer suppresses MMP-2-mediated invasion and VEGFA-induced angiogenesis and serves as a promising prognostic biomarker in human clear cell renal cell carcinoma.
Neoplasm Metastasis
Different levels of TGFbeta, IL-10, IFNgamma and gelatinase A occur in experimental white and black metastases induced by bryostatin 1 or by phorbol ester-treated BL6T murine melanoma cells.
Neoplasm Metastasis
Different Proteins Regulated Apoptosis, Proliferation and Metastasis of Lung Adenocarcinoma After Radiotherapy at Different Time.
Neoplasm Metastasis
Differential expression and origin of membrane-type 1 and 2 matrix metalloproteinases (MT-MMPs) in association with MMP2 activation in injured human livers.
Neoplasm Metastasis
Differential inductions of matrix metalloproteinase-2 and -9 in host tissues during the growth of ascitic sarcoma 180 cells in mice.
Neoplasm Metastasis
Differentially expressed genes between primary cancer and paired lymph node metastases predict clinical outcome of node-positive breast cancer patients.
Neoplasm Metastasis
Direct cell-cell interaction enhances pro-MMP-2 production and activation in co-culture of laryngeal cancer cells and fibroblasts: involvement of EMMPRIN and MT1-MMP.
Neoplasm Metastasis
Distinct endobronchial expression of matrix-metalloproteinases (MMP) and their endogenous inhibitors in lung cancer.
Neoplasm Metastasis
Distinct Functionality of Tumor Cell-Derived Gelatinases during Formation of Liver Metastases.
Neoplasm Metastasis
Domain structure of human 72-kDa gelatinase/type IV collagenase. Characterization of proteolytic activity and identification of the tissue inhibitor of metalloproteinase-2 (TIMP-2) binding regions.
Neoplasm Metastasis
Down-regulation of cathepsin S and matrix metalloproteinase-9 via Src, a non-receptor tyrosine kinase, suppresses triple-negative breast cancer growth and metastasis.
Neoplasm Metastasis
Down-regulation of osteopontin inhibits metastasis of hepatocellular carcinoma cells via a mechanism involving MMP-2 and uPA.
Neoplasm Metastasis
Downregulation of BRCA1 in A375 melanoma cell line increases radio-sensitivity and modifies metastatic and angiogenic gene expression.
Neoplasm Metastasis
Downregulation of the RECK-tumor and metastasis suppressor gene in glioma invasiveness.
Neoplasm Metastasis
Doxorubicin and Trifolium pratense L. (Red clover) extract synergistically inhibits brain and lung metastases in 4T1 tumor-bearing BALB/c mice.
Neoplasm Metastasis
DRP1 upregulation promotes pancreatic cancer growth and metastasis through increased aerobic glycolysis.
Neoplasm Metastasis
EFEMP1 promotes the migration and invasion of osteosarcoma via MMP-2 with induction by AEG-1 via NF-?B signaling pathway.
Neoplasm Metastasis
Effect of Fraxiparine, a type of low molecular weight heparin, on the invasion and metastasis of lung adenocarcinoma A549 cells.
Neoplasm Metastasis
Effect of isofebrifugine on the proliferation and invasion of human gastric cancer cells via MMP.
Neoplasm Metastasis
Effect of matrix metalloproteinase inhibitors on tumor growth and spontaneous metastasis.
Neoplasm Metastasis
Effect of metallothioneins on transformation of gelatinase A from human fibroblast WI-38 cells.
Neoplasm Metastasis
Effect of microRNA-206 on cytoskeleton remodelling by downregulating Cdc42 in MDA-MB-231 cells.
Neoplasm Metastasis
Effect of Sirtuin 1 inhibition on matrix metalloproteinase 2 and Forkhead box O3a expression in breast cancer cells.
Neoplasm Metastasis
Effect of troglitazone on tumor growth and pulmonary metastasis development of the mouse osteosarcoma cell line LM8.
Neoplasm Metastasis
Effects of a KiSS-1 peptide, a metastasis suppressor gene, on the invasive ability of renal cell carcinoma cells through a modulation of a matrix metalloproteinase 2 expression.
Neoplasm Metastasis
Effects of cigarette smoke condensate on oral squamous cell carcinoma cells.
Neoplasm Metastasis
Effects of hepatocyte growth factor/scatter factor on the invasion of colorectal cancer cells in vitro.
Neoplasm Metastasis
Effects of Lidocaine and Src Inhibition on Metastasis in a Murine Model of Breast Cancer Surgery.
Neoplasm Metastasis
Effects of linoleic acid on the growth and metastasis of two human breast cancer cell lines in nude mice and the invasive capacity of these cell lines in vitro.
Neoplasm Metastasis
Effects of nutrients on matrix metalloproteinases in human T-lymphotropic virus type 1 positive and negative malignant T-lymphocytes.
Neoplasm Metastasis
Effects of zoledronic acid on proteinase plasma levels in patients with bone metastases.
Neoplasm Metastasis
EGCG inhibits the invasion of highly invasive CL1-5 lung cancer cells through suppressing MMP-2 expression via JNK signaling and induces G2/M arrest.
Neoplasm Metastasis
Elevated plasma levels of matrix metalloproteinase-9 (92-kd type IV collagenase/gelatinase B) in hepatocellular carcinoma.
Neoplasm Metastasis
Endometrial tumor invasiveness is related to metalloproteinase 2 and tissue inhibitor of metalloproteinase 2 expressions.
Neoplasm Metastasis
Enhanced cell surface expression of matrix metalloproteinases and their inhibitors, and tumor-induced host response in progression of human gastric carcinoma.
Neoplasm Metastasis
Enhanced expression of tissue inhibitor of metalloproteinase-2 (TIMP-2) in the stroma of breast carcinomas correlates with tumor recurrence.
Neoplasm Metastasis
Enhanced expression of tissue inhibitors of metalloproteinases in human colorectal tumors.
Neoplasm Metastasis
Enhanced production and activation of progelatinase A mediated by membrane-type 1 matrix metalloproteinase in human oral squamous cell carcinomas: implications for lymph node metastasis.
Neoplasm Metastasis
Enhanced production of matrix metalloproteinase-2 in human head and neck carcinomas is correlated with lymph node metastasis.
Neoplasm Metastasis
Enhancement of membrane-type 1-matrix metalloproteinase (MT1-MMP) production and sequential activation of progelatinase A on human squamous carcinoma cells co-cultured with human dermal fibroblasts.
Neoplasm Metastasis
Environmental endocrine disruptors promote invasion and metastasis of SK-N-SH human neuroblastoma cells.
Neoplasm Metastasis
Epidermal growth factor receptor regulates MT1-MMP and MMP-2 synthesis in SiHa cells via both PI3-K/AKT and MAPK/ERK pathways.
Neoplasm Metastasis
Epidermal growth factor receptor-mediated regulation of matrix metalloproteinase-2 and matrix metalloproteinase-9 in MCF-7 breast cancer cells.
Neoplasm Metastasis
Epigenetic regulation of multidrug-resistance and metastasis-related genes in human lung adenocarcinoma cells growing in ectopic or orthotopic organs of nude-mice.
Neoplasm Metastasis
Esophageal Cancer Development: Crucial Clues Arising from the Extracellular Matrix.
Neoplasm Metastasis
Estrogen promotes tumor metastasis via estrogen receptor beta-mediated regulation of matrix-metalloproteinase-2 in non-small cell lung cancer.
Neoplasm Metastasis
ETS-1 regulates vascular endothelial growth factor-induced matrix metalloproteinase-9 and matrix metalloproteinase-13 expression in human ovarian carcinoma cell SKOV-3.
Neoplasm Metastasis
Eupatilin inhibits angiogenesis-mediated human hepatocellular metastasis by reducing MMP-2 and VEGF signaling.
Neoplasm Metastasis
Evaluation of basement membrane components and the 72 kDa type IV collagenase in serous tumors of the ovary.
Neoplasm Metastasis
Evaluation of Suppressive Effects of Tranilast on the Invasion/Metastasis Mechanism in a Murine Pancreatic Cancer Cell Line.
Neoplasm Metastasis
Evidence for increased activated metalloproteinase 2 (MMP-2a) expression associated with human prostate cancer progression.
Neoplasm Metastasis
Evidence for tumor-host cooperation in regulating MMP-2 expression in human colon cancer.
Neoplasm Metastasis
Evidence of the involvement of phosphatidylinositol 3-kinase in the migration, actin stress fiber formation, and alpha v beta 3-integrin-mediated adherence of human melanoma cells.
Neoplasm Metastasis
Exosome EpCAM promotes the metastasis of glioma by targeting the CD44 signaling molecule on the surface of glioma cells.
Neoplasm Metastasis
Exploring QSAR and pharmacophore mapping of structurally diverse selective matrix metalloproteinase-2 inhibitors.
Neoplasm Metastasis
Exploring the action of RGDV-gemcitabine on tumor metastasis, tumor growth and possible action pathway.
Neoplasm Metastasis
Exploring the Mechanism of Flaccidoxide-13-Acetate in Suppressing Cell Metastasis of Hepatocellular Carcinoma.
Neoplasm Metastasis
Expression analysis and clinical significance of eIF4E, VEGF-C, E-cadherin and MMP-2 in colorectal adenocarcinoma.
Neoplasm Metastasis
Expression and activation of matrix metalloproteinase-2 (MMP-2) and its co-localization with membrane-type 1 matrix metalloproteinase (MT1-MMP) correlate with melanoma progression.
Neoplasm Metastasis
Expression and clinical significance of HMGB1 in human liver cancer: Knockdown inhibits tumor growth and metastasis in vitro and in vivo.
Neoplasm Metastasis
Expression and clinical significance of matrix metalloproteinase-2 and matrix metalloproteinase-9 in oral squamous cell carcinoma.
Neoplasm Metastasis
Expression and localization of 72 kDa type IV collagenase (MMP-2) in human malignant gliomas in vivo.
Neoplasm Metastasis
Expression and quantitative analysis of matrix metalloproteinase-2 and -9 in human gliomas.
Neoplasm Metastasis
Expression and serum levels of MMP-2 and MMP-9 during human melanoma progression.
Neoplasm Metastasis
Expression and significance of MMP2 and HIF-1? in hepatocellular carcinoma.
Neoplasm Metastasis
Expression and tissue localization of membrane-type 1, 2, and 3 matrix metalloproteinases in human astrocytic tumors.
Neoplasm Metastasis
Expression and tissue localization of membrane-types 1, 2, and 3 matrix metalloproteinases in human invasive breast carcinomas.
Neoplasm Metastasis
Expression levels of genes that regulate metastasis and angiogenesis correlate with advanced pathological stage of renal cell carcinoma.
Neoplasm Metastasis
Expression of 72 kilodalton type IV collagenase (gelatinase A) in benign and malignant ovarian tumors.
Neoplasm Metastasis
Expression of Alpha-Enolase (ENO1), Myc Promoter-Binding Protein-1 (MBP-1) and Matrix Metalloproteinases (MMP-2 and MMP-9) Reflect the Nature and Aggressiveness of Breast Tumors.
Neoplasm Metastasis
Expression of bcl-2 correlates with poor prognosis and modulates migration of nasopharyngeal carcinoma cells.
Neoplasm Metastasis
Expression of c-erbB receptors, MMPs and VEGF in squamous cell carcinoma of the head and neck.
Neoplasm Metastasis
Expression of C-X-C chemokine receptor types 1/2 in patients with gastric carcinoma: Clinicopathological correlations and significance.
Neoplasm Metastasis
Expression of collagenase IV (basement membrane collagenase) activity in murine tumor cell hybrids that differ in metastatic potential.
Neoplasm Metastasis
Expression of CXCR4 and MMP-2 is associated with poor prognosis in patients with osteosarcoma.
Neoplasm Metastasis
Expression of cyclooxygenase-2, vascular endothelial growth factor and matrix metalloproteinase-2 in patients with primary laryngeal carcinoma: a tissue microarray study.
Neoplasm Metastasis
Expression of cytokeratin 19 and matrix metalloproteinase 2 predicts lymph node metastasis in hepatocellular carcinoma.
Neoplasm Metastasis
Expression of Discoidin Domain Receptor 2 (DDR2) Extracellular Domain in Pichia Pastoris and Functional Analysis in Synovial Fibroblasts and NIT3T3 Cells.
Neoplasm Metastasis
Expression of EMMPRIN in adenoid cystic carcinoma of salivary glands: correlation with tumor progression and patients' prognosis.
Neoplasm Metastasis
Expression of FLJ10540 is correlated with aggressiveness of oral cavity squamous cell carcinoma by stimulating cell migration and invasion through increased FOXM1 and MMP-2 activity.
Neoplasm Metastasis
Expression of gelatinase-A (MMP-2) in human colon cancer and normal colon mucosa.
Neoplasm Metastasis
Expression of gelatinases A and B, stromelysin-3 and matrilysin genes in breast carcinomas: clinico-pathological correlations.
Neoplasm Metastasis
Expression of integrin alphaVbeta3 in pancreatic carcinoma: relation to MMP-2 activation and lymph node metastasis.
Neoplasm Metastasis
Expression of interleukin-8 by human melanoma cells up-regulates MMP-2 activity and increases tumor growth and metastasis.
Neoplasm Metastasis
Expression of laminin, collagen IV, fibronectin, and type IV collagenase in gastric carcinoma. An immunohistochemical study of 87 patients.
Neoplasm Metastasis
Expression of matrix metalloproteinase (MMP)-2, MMP-9, and tissue inhibitor of MMP (TIMP)-1 in conjunctival melanomas and clinical implications.
Neoplasm Metastasis
Expression of matrix metalloproteinase 2 (MMP-2), E-cadherin and Ki-67 in metastatic and non-metastatic canine mammary carcinomas.
Neoplasm Metastasis
Expression of matrix metalloproteinase 2 and its tissue inhibitor in oral squamous cell carcinoma.
Neoplasm Metastasis
Expression of matrix metalloproteinase-2 and -9 in oral squamous cell carcinomas with regard to the metastatic potential.
Neoplasm Metastasis
Expression of matrix metalloproteinase-2 and its tissue inhibitor-2 in fetal and neoplastic thyroid tissue and their significance as diagnostic and prognostic markers in papillary carcinoma.
Neoplasm Metastasis
Expression of matrix metalloproteinase-2 and prostate-specific antigen in localized and metastatic prostate cancer.
Neoplasm Metastasis
Expression of matrix metalloproteinase-2 related to lymph node metastasis of oral squamous cell carcinoma. A clinicopathologic study.
Neoplasm Metastasis
Expression of matrix metalloproteinases 1 and 2 genes in a possible association with metastatic abilities of human pancreatic cancer cells.
Neoplasm Metastasis
Expression of Matrix Metalloproteinases and Its Inhibitor in Gastric Adenocarcinoma.
Neoplasm Metastasis
Expression of matrix metalloproteinases in patients with uterine smooth muscle tumors: an immunohistochemical analysis of MMP-1 and MMP-2 protein expression in leiomyoma, uterine smooth muscle tumor of uncertain malignant potential, and leiomyosarcoma.
Neoplasm Metastasis
Expression of matrix metalloproteinases in supraglottic carcinoma and its clinical implication for estimating lymph node metastases.
Neoplasm Metastasis
Expression of matrix metalloproteinases in the microenvironment of spontaneous and experimental melanoma metastases reflects the requirements for tumor formation.
Neoplasm Metastasis
Expression of matrix metalloproteinases-2, -8, -13, -26, and tissue inhibitors of metalloproteinase-1 in human osteosarcoma.
Neoplasm Metastasis
Expression of MMP-2 and TIMP-3 with incidence and prognosis of giant-cell tumor of the bone.
Neoplasm Metastasis
Expression of MMP-2 correlates with increased angiogenesis in CNS metastasis of lung carcinoma.
Neoplasm Metastasis
Expression of MMP-2 is associated with progression and lymph node metastasis of gastric carcinoma.
Neoplasm Metastasis
Expression of MMP-2, MMP-9, and urokinase-type plasminogen activator in cervical intraepithelial neoplasia.
Neoplasm Metastasis
Expression of MMP2, MMP9 and MMP3 in breast cancer brain metastasis in a rat model.
Neoplasm Metastasis
Expression of nm23, MMP-2, TIMP-2 in breast neoplasm in Zhengzhou Center Hospital, China.
Neoplasm Metastasis
Expression of peroxisome proliferator-activated receptor g, E-cadherin and matrix metalloproteinases-2 in gastric carcinoma and lymph node metastases.
Neoplasm Metastasis
Expression of PI3K/AKT pathway in gastric cancer and its blockade suppresses tumor growth and metastasis.
Neoplasm Metastasis
Expression of receptor for advanced glycation end products (RAGE) and MMP-9 in human pancreatic cancer cells.
Neoplasm Metastasis
Expression of SHP2 and Related Markers in Non-Small Cell Lung Cancer: A Tissue Microarray Study of 80 Cases.
Neoplasm Metastasis
Expression of tissue inhibitor of matrix metalloproteinase-2 correlates with activation of matrix metalloproteinase-2 and predicts poor prognosis in tongue squamous cell carcinoma.
Neoplasm Metastasis
Expression of tissue levels of matrix metalloproteinases and their inhibitors in breast cancer.
Neoplasm Metastasis
Expression of tissue levels of matrix metalloproteinases and tissue inhibitors of metalloproteinases in gastric adenocarcinoma.
Neoplasm Metastasis
Expression of TRAP1 in gastric cancer tissue and its correlation with malignant biology.
Neoplasm Metastasis
Expression of type IV collagen and matrix metalloproteinase-2 (type IV collagenase) in relation to nodal status in laryngeal cancer.
Neoplasm Metastasis
Expression of type IV collagenase and procollagen genes and its correlation with the tumorigenic, invasive, and metastatic abilities of oncogene-transformed human bronchial epithelial cells.
Neoplasm Metastasis
Expression of vascular endothelial growth factor and matrix metalloproteinase-2 correlates with the invasion and metastasis of hepatocellular carcinoma.
Neoplasm Metastasis
Expression of WTH3 in breast cancer tissue and the effects on the biological behavior of breast cancer cells.
Neoplasm Metastasis
Expression of Yes-associated protein in gastric adenocarcinoma and inhibitory effects of its knockdown on gastric cancer cell proliferation and metastasis.
Neoplasm Metastasis
Expression patterns of seprase, a membrane serine protease, in cervical carcinoma and cervical intraepithelial neoplasm.
Neoplasm Metastasis
Expression, purification, refolding and in vitro recovery of active full length recombinant human gelatinase MMP-9 in Escherichia coli.
Neoplasm Metastasis
Expressions of CD147, MMP-2 and MMP-9 in Laryngeal Carcinoma and its Correlation with Poor Prognosis.
Neoplasm Metastasis
Expressions of MMP-2, MMP-9 and VEGF are closely linked to growth, invasion, metastasis and angiogenesis of gastric carcinoma.
Neoplasm Metastasis
Extracellular matrix expression in metastasizing and nonmetastasizing adenocarcinomas of the lung.
Neoplasm Metastasis
Extracellular matrix metalloproteinase inducer and matrix metalloproteinase-2 overexpression is associated with loss of hormone receptor expression and poor prognosis in endometrial cancer.
Neoplasm Metastasis
Ezrin-Radixin-Moesin Binding Phosphoprotein 50 (EBP50) Suppresses the Metastasis of Breast Cancer and HeLa Cells by Inhibiting Matrix Metalloproteinase-2 Activity.
Neoplasm Metastasis
FAK is involved in invasion and metastasis of hepatocellular carcinoma.
Neoplasm Metastasis
Filamin C, a dysregulated protein in cancer revealed by label-free quantitative proteomic analyses of human gastric cancer cells.
Neoplasm Metastasis
First evidence that the anti-malarial drug Artesunate inhibits invasion and in vivo metastasis in lung cancer by targeting essential extracellular proteases.
Neoplasm Metastasis
Flubendazole elicits anti-metastatic effects in triple-negative breast cancer via STAT3 inhibition.
Neoplasm Metastasis
Folate-decorated arginine-based poly(ester urea urethane) nanoparticles as carriers for gambogic acid and effect on cancer cells.
Neoplasm Metastasis
Folate-targeted paclitaxel-conjugated polymeric micelles inhibits pulmonary metastatic hepatoma in experimental murine H22 metastasis models.
Neoplasm Metastasis
Full-length L1CAM and not its ?2?27 splice variant promotes metastasis through induction of gelatinase expression.
Neoplasm Metastasis
Fully human anti-interleukin 8 antibody inhibits tumor growth in orthotopic bladder cancer xenografts via down-regulation of matrix metalloproteases and nuclear factor-kappaB.
Neoplasm Metastasis
Functional expression of CXC chemokine recepter-4 mediates the secretion of matrix metalloproteinases from mouse hepatocarcinoma cell lines with different lymphatic metastasis ability.
Neoplasm Metastasis
Functional haplotypes in the promoter of matrix metalloproteinase-2 predict risk of the occurrence and metastasis of esophageal cancer.
Neoplasm Metastasis
Functional vinorelbine plus schisandrin B liposomes destroying tumor metastasis in treatment of gastric cancer.
Neoplasm Metastasis
Fusion expression of DDR2 extracellular domain in insect cells and its purification and function characterization.
Neoplasm Metastasis
Galloyl cyclic-imide derivative CH1104I inhibits tumor invasion through suppressing matrix metalloproteinase activity.
Neoplasm Metastasis
Gamabufotalin suppressed osteosarcoma stem cells through the TGF-?/periostin/PI3K/AKT pathway.
Neoplasm Metastasis
Ganoderic acid T inhibits tumor invasion in vitro and in vivo through inhibition of MMP expression.
Neoplasm Metastasis
Gaseous nitrogen oxide promotes human lung cancer cell line A549 migration, invasion, and metastasis via iNOS-mediated MMP-2 production.
Neoplasm Metastasis
Gelatinase A and membrane-type 1 matrix metalloproteinase mRNA: expressed in adrenocortical cancers but not in adenomas.
Neoplasm Metastasis
Gelatinase A/TIMP-2 imbalance in lymph-node-positive breast carcinomas, as measured by RT-PCR.
Neoplasm Metastasis
Gelatinase and inhibitor expression in soft tissue sarcomas: lack of correlation with distant metastasis.
Neoplasm Metastasis
Gelatinases A and B expression in human colorectal cancer in upper Egypt: a clinicopathological study.
Neoplasm Metastasis
Gelatinases and their inhibitors in tumor metastasis: from biological research to medical applications.
Neoplasm Metastasis
Gelatinolytic activity of matrix metalloproteinase-2 and -9 in oesophageal carcinoma; a study using in situ zymography.
Neoplasm Metastasis
Gene Expression Profiling of Fixed Tissues Identified Hypoxia-Inducible Factor-1{alpha}, VEGF, and Matrix Metalloproteinase-2 as Biomarkers of Lymph Node Metastasis in Hepatocellular Carcinoma.
Neoplasm Metastasis
Generation and antitumor effects of an engineered and energized fusion protein VL-LDP-AE composed of single-domain antibody and lidamycin.
Neoplasm Metastasis
Genetic Predisposition of Polymorphisms in HMGB1-Related Genes to Breast Cancer Prognosis in Korean Women.
Neoplasm Metastasis
Genistein inhibits p38 map kinase activation, matrix metalloproteinase type 2, and cell invasion in human prostate epithelial cells.
Neoplasm Metastasis
Genistein reinforces the inhibitory effect of Cisplatin on liver cancer recurrence and metastasis after curative hepatectomy.
Neoplasm Metastasis
Genistein treatment duration effects biomarkers of cell motility in human prostate.
Neoplasm Metastasis
Genistein-selenium combination induces growth arrest in prostate cancer cells.
Neoplasm Metastasis
GHGKHKNK Octapeptide (P-5m) Inhibits Metastasis of HCCLM3 Cell Lines via Regulation of MMP-2 Expression in in Vitro and in Vivo Studies.
Neoplasm Metastasis
GOLPH3 Overexpression is Closely Correlated with Poor Prognosis in Human Non-Small Cell Lung Cancer and Mediates its Metastasis Through Upregulating MMP-2 and MMP-9.
Neoplasm Metastasis
Granulocyte colony-stimulating factor (G-CSF)-mediated signaling regulates type IV collagenase activity in head and neck cancer cells.
Neoplasm Metastasis
Granulocyte-macrophage colony-stimulating factor upregulates matrix metalloproteinase-2 (MMP-2) and membrane type-1 MMP (MT1-MMP) in human head and neck cancer cells.
Neoplasm Metastasis
HAND2-AS1 inhibits invasion and metastasis of cervical cancer cells via microRNA-330-5p-mediated LDOC1.
Neoplasm Metastasis
HIF-1? contributes to hypoxia-induced invasion and metastasis of esophageal carcinoma via inhibiting E-cadherin and promoting MMP-2 expression.
Neoplasm Metastasis
HIF-2? as a prognostic marker for breast cancer progression and patient survival.
Neoplasm Metastasis
High Expression of GRP78 Promotes Invasion and Metastases in Patients with Esophageal Squamous Cell Carcinoma.
Neoplasm Metastasis
High Expression of MMP-9 in Primary Tumors and High Preoperative MPO in Serum Predict Improved Prognosis in Colorectal Cancer with Operable Liver Metastases.
Neoplasm Metastasis
High Mobility Group Box Protein 1 Serves as a Potential Prognostic Marker of Lung Cancer and Promotes Its Invasion and Metastasis by Matrix Metalloproteinase-2 in a Nuclear Factor-?B-Dependent Manner.
Neoplasm Metastasis
High threshold of ?1 integrin inhibition required to block collagen I-induced membrane type-1 matrix metalloproteinase (MT1-MMP) activation of matrix metalloproteinase 2 (MMP-2).
Neoplasm Metastasis
High VEGF-D and Low MMP-2 Serum Levels Predict Nodal-Positive Disease in Invasive Bladder Cancer.
Neoplasm Metastasis
High-throughput functional profiling of single adherent cells via hydrogel drop-screen.
Neoplasm Metastasis
Highly activated matrix metalloproteinase-2 secreted from clones of metastatic lung nodules of nude mice injected with human fibrosarcoma HT1080.
Neoplasm Metastasis
Hispolon suppresses SK-Hep1 human hepatoma cell metastasis by inhibiting matrix metalloproteinase-2/9 and urokinase-plasminogen activator through the PI3K/Akt and ERK signaling pathways.
Neoplasm Metastasis
Histologic features of venous invasion, expression of vascular endothelial growth factor and matrix metalloproteinase-2 and matrix metalloproteinase-9, and the relation with liver metastasis in pancreatic cancer.
Neoplasm Metastasis
HMGA2 gene silencing reduces epithelial-mesenchymal transition and lymph node metastasis in cervical cancer through inhibiting the ATR/Chk1 signaling pathway.
Neoplasm Metastasis
Host expression of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in normal colon tissue affects metastatic potential of colorectal cancer.
Neoplasm Metastasis
Human papillomavirus E6-regulated microRNA-20b promotes invasion in cervical cancer by targeting tissue inhibitor of metalloproteinase 2.
Neoplasm Metastasis
Hypoxia level and matrix metalloproteinases-2 and -9 activity in Lewis lung carcinoma: correlation with metastasis.
Neoplasm Metastasis
Hypoxia-reoxygenation increase invasiveness of PANC-1 cells through Rac1/MMP-2.
Neoplasm Metastasis
Icariside II from Epimedium koreanum inhibits hypoxia-inducible factor-1alpha in human osteosarcoma cells.
Neoplasm Metastasis
Identification of a Potent Oridonin Analogue for Treatment of Triple-Negative Breast Cancer.
Neoplasm Metastasis
Identification of an amino acid sequence from the laminin A chain that stimulates metastasis and collagenase IV production.
Neoplasm Metastasis
Identification of Non-Zinc Binding Inhibitors of MMP-2 Through Virtual Screening and Subsequent Rescoring.
Neoplasm Metastasis
Identification of novel, functional genetic variants in the human matrix metalloproteinase-2 gene: role of Sp1 in allele-specific transcriptional regulation.
Neoplasm Metastasis
Identification of substrate sequences for membrane type-1 matrix metalloproteinase using bacteriophage peptide display library.
Neoplasm Metastasis
IL-10 inhibition of human prostate PC-3 ML cell metastases in SCID mice: IL-10 stimulation of TIMP-1 and inhibition of MMP-2/MMP-9 expression.
Neoplasm Metastasis
IL6-induced metastasis modulators p-STAT3, MMP-2 and MMP-9 are targets of 3,3'-diindolylmethane in ovarian cancer cells.
Neoplasm Metastasis
Imbalance between MMP-2, 9 and TIMP-1 promote the invasion and metastasis of renal cell carcinoma via SKP2 signaling pathways.
Neoplasm Metastasis
Immunoassays of the metalloproteinase (MMP-2) and tissue inhibitor of metalloproteinase (TIMP 1 and 2) levels in noninvasive and metastatic PC-3 clones: effects of taxol.
Neoplasm Metastasis
Immunocytochemical detection of matrix metalloproteinase expression in prostate cancer.
Neoplasm Metastasis
Immunocytochemical detection of the expression of members of the matrix metalloproteinase family in adenocarcinomas of the pancreas.
Neoplasm Metastasis
Immunoexpression of matrix metalloproteinase-2 (MMP-2) in malignant ovarian epithelial tumours.
Neoplasm Metastasis
Immunoexpression of matrix metalloproteinase-2 and matrix metalloproteinase-9 in the metastasis of squamous cell carcinoma of the human tongue.
Neoplasm Metastasis
Immunohistochemical detection of matrix metalloproteinases (MMP) 1 and 2, and tissue inhibitor of metalloproteinase 2 (TIMP 2) in stage I and II endometrial cancer.
Neoplasm Metastasis
Immunohistochemical detection of matrix metalloproteinases (MMP) 1 and 2, and tissue inhibitor of metalloproteinase 2 (TIMP 2) in stage IB cervical cancer.
Neoplasm Metastasis
Immunohistochemical detection of membrane-type-1-matrix metalloproteinase in colorectal carcinoma.
Neoplasm Metastasis
Immunohistochemical distribution of type IV collagenase in normal, dysplastic and neoplastic canine mammary gland.
Neoplasm Metastasis
Immunohistochemical evaluation of MMP-2, MMP-9 and CD31/microvascular density in squamous cell carcinomas of the floor of the mouth.
Neoplasm Metastasis
Immunohistochemical expression of matrix metalloproteinases 1, 2, 9, and 14 in dermatofibrosarcoma protuberans and common fibrous histiocytoma (dermatofibroma).
Neoplasm Metastasis
Immunohistochemical levels of matrix metalloproteinase-2 and CD44 variant 6 protein in the diagnosis and lateral cervical lymph node metastasis of papillary thyroid carcinoma.
Neoplasm Metastasis
Immunohistochemical predictors in squamous cell carcinoma of the tongue and floor of the mouth.
Neoplasm Metastasis
Immunological characterization of cell-surface and soluble forms of membrane type 1 matrix metalloproteinase in human breast cancer cells and in fibroblasts.
Neoplasm Metastasis
Implication of collagen type I-induced membrane-type 1-matrix metalloproteinase expression and matrix metalloproteinase-2 activation in the metastatic progression of breast carcinoma.
Neoplasm Metastasis
In situ detection of matrix metalloproteinase-2 (MMP2) and the metalloproteinase inhibitor TIMP2 transcripts in human primary hepatocellular carcinoma and in liver metastasis.
Neoplasm Metastasis
In situ localization of gelatinolytic activity in the extracellular matrix of metastases of colon cancer in rat liver using quenched fluorogenic DQ-gelatin.
Neoplasm Metastasis
In vitro and in vivo antimetastatic effects of Terminalia catappa L. leaves on lung cancer cells.
Neoplasm Metastasis
In vitro and in vivo matrix metalloproteinase production by pancreatic cancer cells and by distant organs.
Neoplasm Metastasis
In vitro antioxidative potential of lactoferrin and black tea polyphenols and protective effects in vivo on carcinogen activation, DNA damage, proliferation, invasion, and angiogenesis during experimental oral carcinogenesis.
Neoplasm Metastasis
In vitro determination of basement membrane invasion predicts liver metastases in human gastrointestinal carcinoma.
Neoplasm Metastasis
In vitro modulation of MMP-2 and MMP-9 in human cervical and ovarian cancer cell lines by cytokines, inducers and inhibitors.
Neoplasm Metastasis
In vivo imaging of membrane type-1 matrix metalloproteinase with a novel activatable near-infrared fluorescence probe.
Neoplasm Metastasis
Increased E1AF expression in mouse fibrosarcoma promotes metastasis through induction of MT1-MMP expression.
Neoplasm Metastasis
Increased expression and activation of gelatinolytic matrix metalloproteinases is associated with the progression and recurrence of human cervical cancer.
Neoplasm Metastasis
Increased expression and activation of matrix metalloproteinase-2 (MMP-2) in O-1N: hamster oral squamous cell carcinoma with high potential lymph node metastasis.
Neoplasm Metastasis
Increased expression of matrix metalloproteinases (MMP)-2, MMP-9, and the urokinase-type plasminogen activator is associated with progression from benign to advanced ovarian cancer.
Neoplasm Metastasis
Increased expression of seprase, a membrane-type serine protease, is associated with lymph node metastasis in human colorectal cancer.
Neoplasm Metastasis
Increased expression of the Mr 72,000 type IV collagenase in human colonic adenocarcinoma.
Neoplasm Metastasis
Increased extracellular matrix remodeling is associated with tumor progression in human hepatocellular carcinomas.
Neoplasm Metastasis
Increased gelatinase A (MMP-2) and cathepsin B activity in invasive tumor regions of human colon cancer samples.
Neoplasm Metastasis
Increased gelatinase-A and gelatinase-B activities in malignant vs. benign breast tumors.
Neoplasm Metastasis
Increased matrix metalloproteinase 2 concentration and transcript expression in advanced colorectal carcinomas.
Neoplasm Metastasis
Increased plasma MMP-2 protein expression in lymph node-positive patients with colorectal cancer.
Neoplasm Metastasis
Increased serum type IV collagen 7-S levels in patients with hepatic metastasis.
Neoplasm Metastasis
Induction of an invasive phenotype in benign tumor cells with a laminin A-chain synthetic peptide.
Neoplasm Metastasis
Induction of RECK by nonsteroidal anti-inflammatory drugs in lung cancer cells.
Neoplasm Metastasis
Inflammation dampened by gelatinase A cleavage of monocyte chemoattractant protein-3.
Neoplasm Metastasis
Influence of cytokines and growth factors on matrix metalloproteinase-2 production and invasion of human renal cancer.
Neoplasm Metastasis
Influence of oleic acid on the expression, activation and activity of gelatinase A produced by oncogene-transformed human bronchial epithelial cells.
Neoplasm Metastasis
Influence of persistent canine distemper virus infection on expression of RECK, matrix-metalloproteinases and their inhibitors in a canine macrophage/monocytic tumour cell line (DH82).
Neoplasm Metastasis
Influence of the host microenvironment on the clonal selection of human colon carcinoma cells during primary tumor growth and metastasis.
Neoplasm Metastasis
Inhibiting tissue invasion and metastasis as targets for cancer therapy.
Neoplasm Metastasis
Inhibition of AIDS-Kaposi's sarcoma cell induced endothelial cell invasion by TIMP-2 and a synthetic peptide from the metalloproteinase propeptide: implications for an anti-angiogenic therapy.
Neoplasm Metastasis
Inhibition of cancer migration and invasion by knocking down delta-5-desaturase in COX-2 overexpressed cancer cells.
Neoplasm Metastasis
Inhibition of cervical lymph node metastasis by marimastat (BB-2516) in an orthotopic oral squamous cell carcinoma implantation model.
Neoplasm Metastasis
Inhibition of collagenases from mouse lung carcinoma cells by green tea catechins and black tea theaflavins.
Neoplasm Metastasis
Inhibition of gelatinase A (MMP-2) by batimastat and captopril reduces tumor growth and lung metastases in mice bearing Lewis lung carcinoma.
Neoplasm Metastasis
Inhibition of human prostate cancer growth, osteolysis and angiogenesis in a bone metastasis model by a novel mechanism-based selective gelatinase inhibitor.
Neoplasm Metastasis
Inhibition of invasion and metastasis of MHCC97H cells by expression of snake venom cystatin through reduction of proteinases activity and epithelial-mesenchymal transition.
Neoplasm Metastasis
Inhibition of invasion, gelatinase activity, tumor take and metastasis of malignant cells by N-acetylcysteine.
Neoplasm Metastasis
Inhibition of matrix metalloproteinase-14 in osteosarcoma cells by clodronate.
Neoplasm Metastasis
Inhibition of matrix metalloproteinase-2 expression and bladder carcinoma metastasis by halofuginone.
Neoplasm Metastasis
Inhibition of metastasis, angiogenesis, and tumor growth by Chinese herbal cocktail Tien-Hsien Liquid.
Neoplasm Metastasis
Inhibition of MMP-2 and MMP-9 decreases cellular migration, and angiogenesis in in vitro models of retinoblastoma.
Neoplasm Metastasis
Inhibition of organ invasion by the matrix metalloproteinase inhibitor batimastat (BB-94) in two human colon carcinoma metastasis models.
Neoplasm Metastasis
Inhibition of osteolytic bone metastasis of breast cancer by combined treatment with the bisphosphonate ibandronate and tissue inhibitor of the matrix metalloproteinase-2.
Neoplasm Metastasis
Inhibition of tumor angiogenesis by the matrix metalloproteinase-activated anthrax lethal toxin in an orthotopic model of anaplastic thyroid carcinoma.
Neoplasm Metastasis
Inhibition of tumor cell invasion by a highly conserved peptide sequence from the matrix metalloproteinase enzyme prosegment.
Neoplasm Metastasis
Inhibition of Tumor Growth and Metastasis by Non-Small Cell Lung Cancer Cells Transfected with Cyclin D1-Targeted siRNA.
Neoplasm Metastasis
Inhibitors of collagenase IV and cell adhesion reduce the invasive activity of malignant tumour cells.
Neoplasm Metastasis
Inhibitory effect of a gamma-oryzanol-rich fraction from purple rice extract on lipopolysaccharide-induced metastasis in human colon cancer cells.
Neoplasm Metastasis
Inhibitory effect of a selective cyclooxygenase-2 inhibitor on liver metastasis of colon cancer.
Neoplasm Metastasis
Inhibitory effect of chitooligosaccharides on matrix metalloproteinase-9 in human fibrosarcoma cells (HT1080).
Neoplasm Metastasis
Inhibitory effect of emodin on migration, invasion and metastasis of human breast cancer MDA-MB-231 cells in vitro and in vivo.
Neoplasm Metastasis
Inhibitory effect of green tea polyphenols on membrane-type 1 matrix metalloproteinase, MT1-MMP.
Neoplasm Metastasis
Inhibitory effect of penta-acetyl geniposide on C6 glioma cells metastasis by inhibiting matrix metalloproteinase-2 expression involved in both the PI3K and ERK signaling pathways.
Neoplasm Metastasis
Inhibitory effect of the carnosine-gallic acid synthetic peptide on MMP-2 and MMP-9 in human fibrosarcoma HT1080 cells.
Neoplasm Metastasis
Inhibitory effects of Chanling Gao on the proliferation and liver metastasis of transplanted colorectal cancer in nude mice.
Neoplasm Metastasis
Inhibitory effects of oleic and docosahexaenoic acids on lung metastasis by colon-carcinoma-26 cells are associated with reduced matrix metalloproteinase-2 and -9 activities.
Neoplasm Metastasis
Inhibitory effects of tetrandrine on epidermal growth factor-induced invasion and migration in HT29 human colorectal adenocarcinoma cells.
Neoplasm Metastasis
Insulin like growth factor-1 selectively regulates the expression of matrix metalloproteinase-2 in malignant H-ras transformed cells.
Neoplasm Metastasis
Integrin ?v?6 Promotes an Osteolytic Program in Cancer Cells by Upregulating MMP2.
Neoplasm Metastasis
Integrin-linked kinase regulates osteopontin-dependent MMP-2 and uPA expression to convey metastatic function in murine mammary epithelial cancer cells.
Neoplasm Metastasis
Interpreting gelatinase activity in tumor tissue and serum as a prognostic marker of naturally developing canine tumors.
Neoplasm Metastasis
Intrabronchial orthotopic propagation of human lung adenocarcinoma--characterizations of tumorigenicity, invasion and metastasis.
Neoplasm Metastasis
Intracellular expression of a single-chain antibody directed against type IV collagenase inhibits the growth of lung cancer xenografts in nude mice.
Neoplasm Metastasis
Intratumoral heterogeneity and inverse correlation between expression of E-cadherin and collagenase type IV in human gastric carcinomas.
Neoplasm Metastasis
Intratumoral macrophage counts correlate with tumor progression in colorectal cancer.
Neoplasm Metastasis
Introduction of basic fibroblast growth factor gene into mouse renal cell carcinoma cell line enhances its metastatic potential.
Neoplasm Metastasis
Invasion and metastasis: the expression and significance of matrix metalloproteinases in carcinomas of the lung.
Neoplasm Metastasis
Involvement of matrix metalloproteinase 2 and 9 in gambogic acid induced suppression of MDA-MB-435 human breast carcinoma cell lung metastasis.
Neoplasm Metastasis
Involvement of matrix metalloproteinase-2 activity in invasion and metastasis of pancreatic carcinoma.
Neoplasm Metastasis
Involvement of MMP-2 in adriamycin resistance dependent on ERK1/2 signal pathway in human osteosarcoma MG-63 cells.
Neoplasm Metastasis
Involvement of PI3K/PTEN/AKT/mTOR pathway in invasion and metastasis in hepatocellular carcinoma: Association with MMP-9.
Neoplasm Metastasis
Irradiation enhances the metastatic potential of prostatic small cell carcinoma xenografts.
Neoplasm Metastasis
Is dual inhibition of metalloenzymes HDAC-8 and MMP-2 a potential pharmacological target to combat hematological malignancies?
Neoplasm Metastasis
JWA suppresses tumor angiogenesis via Sp1-activated MMP-2 and its prognostic significance in human gastric cancer.
Neoplasm Metastasis
Kaempferol suppresses cell metastasis via inhibition of the ERK-p38-JNK and AP-1 signaling pathways in U-2 OS human osteosarcoma cells.
Neoplasm Metastasis
Ketoprofen in topical formulation decreases the matrix metalloproteinase-2 expression and pulmonary metastatic incidence in nude mice with osteosarcoma.
Neoplasm Metastasis
Knockdown of Angiopoietin-2 Suppresses Metastasis in Human Pancreatic Carcinoma by Reduced Matrix Metalloproteinase-2.
Neoplasm Metastasis
Knockdown of lactate dehydrogenase A suppresses tumor growth and metastasis of human hepatocellular carcinoma.
Neoplasm Metastasis
Korean Byungkyul - Citrus platymamma Hort.et Tanaka flavonoids induces cell cycle arrest and apoptosis, regulating MMP protein expression in Hep3B hepatocellular carcinoma cells.
Neoplasm Metastasis
Lentiviral-mediated Smad4 RNAi promotes SMMC-7721 cell migration by regulation of MMP-2, VEGF and MAPK signaling.
Neoplasm Metastasis
Leptin produced by obese adipose stromal/stem cells enhances proliferation and metastasis of estrogen receptor positive breast cancers.
Neoplasm Metastasis
Leucine-rich repeat-containing G-protein-coupled receptor 5 is associated with invasion, metastasis, and could be a potential therapeutic target in human gastric cancer.
Neoplasm Metastasis
Levels of Circulating TIMP-2 and MMP2-TIMP2 Complex Are Decreased in Squamous Cervical Carcinoma.
Neoplasm Metastasis
Lipid-soluble ginseng extract inhibits invasion and metastasis of B16F10 melanoma cells.
Neoplasm Metastasis
Liver metastasis formation by laminin-1 peptide (LQVQLSIR)-adhesion selected B16-F10 melanoma cells.
Neoplasm Metastasis
LncRNA GAS5 is a critical regulator of metastasis phenotype of melanoma cells and inhibits tumor growth in vivo.
Neoplasm Metastasis
Long non-coding RNA SNHG15 indicates poor prognosis of non-small cell lung cancer and promotes cell proliferation and invasion.
Neoplasm Metastasis
Long Noncoding RNA Highly Up-regulated in Liver Cancer Predicts Unfavorable Outcome and Regulates Metastasis by MMPs in Triple-negative Breast Cancer.
Neoplasm Metastasis
Low expression of reversion-inducing cysteine-rich protein with Kazal motifs (RECK) indicates a shorter survival after resection in patients with adenocarcinoma of the lung.
Neoplasm Metastasis
Luteolin inhibits the proliferation, adhesion, migration and invasion of choroidal melanoma cells in vitro.
Neoplasm Metastasis
Lymph Node Metastasis of Gastric Cancer Is Associated with the Interaction Between Poly (ADP-Ribose) Polymerase 1 and Matrix Metallopeptidase 2.
Neoplasm Metastasis
Lymph node micrometastasis and its correlation with MMP-2 expression in gastric carcinoma.
Neoplasm Metastasis
Macrophage migration inhibitory factor promotes the invasion and metastasis of oral squamous cell carcinoma through matrix metalloprotein-2/9.
Neoplasm Metastasis
MAG-2 promotes invasion, mobility and adherence capability of lung cancer cells by MMP-2, CD44 and intracellular calcium in vitro.
Neoplasm Metastasis
Magnetic Semiconductor Gd-Doping CuS Nanoparticles as Activatable Nanoprobes for Bimodal Imaging and Targeted Photothermal Therapy of Gastric Tumors.
Neoplasm Metastasis
MAGP2, a Component of Extracellular Matrix, Is Upregulated in Colorectal Cancer and Negatively Modulated by miR-200b-3p.
Neoplasm Metastasis
Mast Cell Infiltration in Human Brain Metastases Modulates the Microenvironment and Contributes to the Metastatic Potential.
Neoplasm Metastasis
Matrix metalloproteinase 2 (MMP-2) immunoreactive protein is associated with poor grade and survival in brain neoplasms.
Neoplasm Metastasis
Matrix metalloproteinase 2 and 9 activity in patients with colorectal cancer liver metastasis.
Neoplasm Metastasis
Matrix metalloproteinase 2 immunoreactive protein appears early in cervical epithelial dedifferentiation.
Neoplasm Metastasis
Matrix metalloproteinase 9 expression is induced by Epstein-Barr virus latent membrane protein 1 C-terminal activation regions 1 and 2.
Neoplasm Metastasis
Matrix metalloproteinase expression in malignant melanomas: tumor-extracellular matrix interactions in invasion and metastasis.
Neoplasm Metastasis
Matrix metalloproteinase inhibitor RO 28-2653 decreases liver metastasis by reduction of MMP-2 and MMP-9 concentration in BOP-induced ductal pancreatic cancer in Syrian Hamsters: inhibition of matrix metalloproteinases in pancreatic cancer.
Neoplasm Metastasis
Matrix metalloproteinase-2 (72 kD type IV collagenase) expression occurs in the early stage of human melanocytic tumour progression and may have prognostic value.
Neoplasm Metastasis
Matrix metalloproteinase-2 (MMP-2) and its tissue inhibitor (TIMP-2) are prognostic factors in cervical cancer, related to invasive disease but not to high-risk human papillomavirus (HPV) or virus persistence after treatment of CIN.
Neoplasm Metastasis
Matrix metalloproteinase-2 (MMP-2) and MMP-9 expression in invasive ductal carcinoma of the breast.
Neoplasm Metastasis
Matrix metalloproteinase-2 (MMP-2) immunoreactive protein--a new prognostic marker in uveal melanoma?
Neoplasm Metastasis
Matrix metalloproteinase-2 and -9 as promising benefactors in development, plasticity and repair of the nervous system.
Neoplasm Metastasis
Matrix metalloproteinase-2 and -9 in bile as a marker of liver metastasis in colorectal cancer.
Neoplasm Metastasis
Matrix metalloproteinase-2 and tissue inhibitor of metallo-proteinase-2 in colorectal carcinoma invasion and metastasis.
Neoplasm Metastasis
Matrix metalloproteinase-2 as a target for head and neck cancer therapy.
Neoplasm Metastasis
Matrix metalloproteinase-2 contributes to cancer cell migration on collagen.
Neoplasm Metastasis
Matrix metalloproteinase-2 expression in laryngeal preneoplastic and neoplastic lesions.
Neoplasm Metastasis
Matrix metalloproteinase-2 expression in stromal tissues is a consistent prognostic factor in stage II colon cancer.
Neoplasm Metastasis
Matrix metalloproteinase-2 immunoreactive protein as a prognostic marker in bladder cancer.
Neoplasm Metastasis
Matrix metalloproteinase-2 involvement in breast cancer progression: a mini-review.
Neoplasm Metastasis
Matrix metalloproteinase-2 polymorphisms and breast cancer susceptibility.
Neoplasm Metastasis
Matrix metalloproteinase-9 from bone marrow-derived cells contributes to survival but not growth of tumor cells in the lung microenvironment.
Neoplasm Metastasis
Matrix metalloproteinases 2 and 9 (gelatinases A and B) expression in malignant mesothelioma and benign pleura.
Neoplasm Metastasis
Matrix metalloproteinases 2 and 9 in situ mRNA expression in colorectal tumors from Iraqi patients.
Neoplasm Metastasis
Matrix metalloproteinases and their inhibitors in correlation to proliferative and classical tumour markers during surgical therapy of colorectal liver metastases.
Neoplasm Metastasis
Matrix metalloproteinases as diagnostic (MMP-13) and prognostic (MMP-2, MMP-9) markers of prostate cancer.
Neoplasm Metastasis
Matrix metalloproteinases in human melanoma cell lines and xenografts: increased expression of activated matrix metalloproteinase-2 (MMP-2) correlates with melanoma progression.
Neoplasm Metastasis
Matrix metalloproteinases in rectal mucosa, tumour and plasma: response after preoperative irradiation.
Neoplasm Metastasis
Matrix metalloproteinases in Vietnamese patients with colorectal cancer.
Neoplasm Metastasis
Matrix metalloproteinases may contribute compensationally to tumor invasion in T1 colorectal carcinomas.
Neoplasm Metastasis
Matrix proteases, green tea, and St. John's wort: biomedical research catches up with folk medicine.
Neoplasm Metastasis
MCU-dependent mitochondrial Ca(2+) inhibits NAD(+)/SIRT3/SOD2 pathway to promote ROS production and metastasis of HCC cells.
Neoplasm Metastasis
Mechanism of metastasis inhibition by cartilage polysaccharide in breast cancer cells.
Neoplasm Metastasis
MED28 and forkhead box M1 (FOXM1) mediate matrix metalloproteinase 2 (MMP2)-dependent cellular migration in human nonsmall cell lung cancer (NSCLC) cells.
Neoplasm Metastasis
MEK4 function, genistein treatment, and invasion of human prostate cancer cells.
Neoplasm Metastasis
Melanoma differentiation-associated gene-7 suppresses human gastric cancer cell invasion and migration.
Neoplasm Metastasis
Membrane-type matrix metalloproteinase expression and matrix metalloproteinase-2 activation in primary human ovarian epithelial carcinoma cells.
Neoplasm Metastasis
Messenger RNA expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human hepatocellular carcinoma.
Neoplasm Metastasis
Metallopeptidase, neurolysin, as a novel molecular tool for analysis of properties of cancer-producing matrix metalloproteinases-2 and -9.
Neoplasm Metastasis
Metalloproteinase-2 expression correlates with aggressiveness of cutaneous squamous cell carcinomas.
Neoplasm Metastasis
Metalloproteinases and their inhibitors: Influence on tumor invasiveness and metastasis formation in head and neck squamous cell carcinomas.
Neoplasm Metastasis
Metastasis of human colon tumor cells in vivo: correlation with the overexpression of plasminogen activators and 72 kDa gelatinase.
Neoplasm Metastasis
Metastatic Inhibitory and Radical Scavenging Efficacies of Saponins Extracted from the Brittle Star (Ophiocoma erinaceus).
Neoplasm Metastasis
Metformin Inhibited Growth, Invasion and Metastasis of Esophageal Squamous Cell Carcinoma in Vitro and in Vivo.
Neoplasm Metastasis
Methionine deprivation suppresses triple-negative breast cancer metastasis in vitro and in vivo.
Neoplasm Metastasis
Microcystin-LR promotes melanoma cell invasion and enhances matrix metalloproteinase-2/-9 expression mediated by NF-?B activation.
Neoplasm Metastasis
Microenvironment-induced TIMP2 loss by cancer-secreted exosomal miR-4443 promotes liver metastasis of breast cancer.
Neoplasm Metastasis
MicroRNA-20b inhibits trophoblast cell migration and invasion by targeting MMP-2.
Neoplasm Metastasis
MicroRNA-29a promotes colorectal cancer metastasis by regulating matrix metalloproteinase 2 and E-cadherin via KLF4.
Neoplasm Metastasis
MicroRNA-29b attenuates non-small cell lung cancer metastasis by targeting matrix metalloproteinase 2 and PTEN.
Neoplasm Metastasis
MicroRNA-29b suppresses tumor angiogenesis, invasion and metastasis by regulating MMP-2 expression.
Neoplasm Metastasis
MicroRNA-708 activation by glucocorticoid receptor agonists regulate breast cancer tumorigenesis and metastasis via downregulation of NF-?B signaling.
Neoplasm Metastasis
miR-143 inhibits the metastasis of pancreatic cancer and an associated signaling pathway.
Neoplasm Metastasis
miR-29b enhances prostate cancer cell invasion independently of MMP-2 expression.
Neoplasm Metastasis
miR-302b suppresses cell invasion and metastasis by directly targeting AKT2 in human hepatocellular carcinoma cells.
Neoplasm Metastasis
miR-338-3p inhibits cell growth, invasion, and EMT process in neuroblastoma through targeting MMP-2.
Neoplasm Metastasis
MiR-95-5p involves in the migration and invasion of trophoblast cells by targeting low density lipoprotein receptor-related protein 6.
Neoplasm Metastasis
miRNA-218 inhibits osteosarcoma cell migration and invasion by down-regulating of TIAM1, MMP2 and MMP9.
Neoplasm Metastasis
MMI-166, a selective matrix metalloproteinase inhibitor, promotes apoptosis in human pancreatic cancer.
Neoplasm Metastasis
MMP-1 and MMP-2 expression in uterine leiomyosarcoma and correlation with different clinicopathologic parameters.
Neoplasm Metastasis
MMP-2 and MMP-9 gene polymorphisms associated with cervical cancer risk.
Neoplasm Metastasis
MMP-2 and TIMP-2 in Cutaneous Melanoma: Association With Prognostic Factors and Description in Cutaneous Metastases.
Neoplasm Metastasis
MMP-2 but not MMP-9 associated with COX-2 and survival in gastric cancer.
Neoplasm Metastasis
MMP-2 functions as an early response protein in ovarian cancer metastasis.
Neoplasm Metastasis
MMP-2 null mice exhibit an early onset and severe experimental autoimmune encephalomyelitis due to an increase in MMP-9 expression and activity.
Neoplasm Metastasis
MMP-2 positivity and age less than 40 years increases the risk for recurrence in premenopausal patients with node-positive breast carcinoma.
Neoplasm Metastasis
MMP-2 siRNA induced Fas/CD95-mediated extrinsic II apoptotic pathway in the A549 lung adenocarcinoma cell line.
Neoplasm Metastasis
MMP-2 together with MMP-9 overexpression correlated with lymph node metastasis and poor prognosis in early gastric carcinoma.
Neoplasm Metastasis
MMP-2, MMP-9 and activin A blood levels in patients with breast cancer or prostate cancer metastatic to the bone.
Neoplasm Metastasis
MMP-9 directed shRNAs as relevant inhibitors of matrix metalloproteinase 9 activity and signaling.
Neoplasm Metastasis
MMP-9 from sublethally irradiated tumor promotes Lewis lung carcinoma cell invasiveness and pulmonary metastasis.
Neoplasm Metastasis
MMP-9-hemopexin domain hampers adhesion and migration of colorectal cancer cells.
Neoplasm Metastasis
MMP2 role in breast cancer brain metastasis development and its regulation by TIMP2 and ERK1/2.
Neoplasm Metastasis
Modulation of membrane type 1 matrix metalloproteinase by LPS and gamma interferon bound to extracellular matrix in intestinal crypt cells.
Neoplasm Metastasis
Modulation of MMP-2 and MMP-9 by cytokines, mitogens and inhibitors in lung cancer and malignant mesothelioma cell lines.
Neoplasm Metastasis
Modulation of plasminogen activation and type IV collagenase activity by a synthetic peptide derived from the laminin A chain.
Neoplasm Metastasis
Molecular basis for the critical role of suppressor of cytokine signaling-1 in melanoma brain metastasis.
Neoplasm Metastasis
Molecular docking and inhibition of matrix metalloproteinase-2 by novel difluorinatedbenzylidene curcumin analog.
Neoplasm Metastasis
Molecular dynamics simulations of metalloproteinases types 2 and 3 reveal differences in the dynamic behavior of the S1' binding pocket.
Neoplasm Metastasis
Molecular mechanisms behind the biological effects of hesperidin and hesperetin for the prevention of cancer and cardiovascular diseases.
Neoplasm Metastasis
MSH6 Aggravates the Hypoxic Microenvironment via Regulating HIF1A to Promote the Metastasis of Glioblastoma Multiforme.
Neoplasm Metastasis
Multi-layered proteogenomic analysis unravels cancer metastasis directed by MMP-2 and focal adhesion kinase signaling.
Neoplasm Metastasis
Multidrug-resistant tumor cells with decreased malignancy: a role for integrin alphavbeta3.
Neoplasm Metastasis
Multiparametric in situ mRNA hybridization analysis to predict disease recurrence in patients with colon carcinoma.
Neoplasm Metastasis
Multiple molecular modelling studies on some derivatives and analogues of glutamic acid as matrix metalloproteinase-2 inhibitors.
Neoplasm Metastasis
Multistage-responsive nanovehicle to improve tumor penetration for dual-modality imaging-guided photodynamic-immunotherapy.
Neoplasm Metastasis
N-?-acetyltransferase 10 protein promotes metastasis by stabilizing matrix metalloproteinase-2 protein in human osteosarcomas.
Neoplasm Metastasis
N-O-Isopropyl Sulfonamido-Based Hydroxamates as Matrix Metalloproteinase Inhibitors: Hit Selection and in Vivo Antiangiogenic Activity.
Neoplasm Metastasis
Naringin suppresses cell metastasis and the expression of matrix metalloproteinases (MMP-2 and MMP-9) via the inhibition of ERK-P38-JNK signaling pathway in human glioblastoma.
Neoplasm Metastasis
Near-Infrared-Activated Fluorescence Resonance Energy Transfer-Based Nanocomposite to Sense MMP2-Overexpressing Oral Cancer Cells.
Neoplasm Metastasis
Neural cell adhesion molecule potentiates invasion and metastasis of melanoma cells through CAMP-dependent protein kinase and phosphatidylinositol 3-kinase pathways.
Neoplasm Metastasis
New clinical scoring system for prognosis of early recurrence of colorectal liver metastases after surgical treatment.
Neoplasm Metastasis
New NSAID-Pt(IV) prodrugs to suppress metastasis and invasion of tumor cells and enhance anti-tumor effect in vitro and in vivo.
Neoplasm Metastasis
NIH/3T3 cells transfected with human tumor DNA containing activated ras oncogenes express the metastatic phenotype in nude mice.
Neoplasm Metastasis
NIK- and IKK?-binding protein promotes colon cancer metastasis by activating the classical NF-?B pathway and MMPs.
Neoplasm Metastasis
Non-steroidal anti-inflammatory drugs inhibit matrix metalloproteinase-2 expression via repression of transcription in lung cancer cells.
Neoplasm Metastasis
Novel quinolone CHM-1 induces apoptosis and inhibits metastasis in a human osterogenic sarcoma cell line.
Neoplasm Metastasis
NRAGE suppresses metastasis of melanoma and pancreatic cancer in vitro and in vivo.
Neoplasm Metastasis
O-Phenyl Carbamate and Phenyl Urea Thiiranes as Selective Matrix Metalloproteinase-2 Inhibitors that Cross the Blood-Brain Barrier.
Neoplasm Metastasis
Oct-3/4 expression reflects tumor progression and regulates motility of bladder cancer cells.
Neoplasm Metastasis
Oral and IV Dosages of Doxorubicin-Methotrexate loaded- Nanoparticles Inhibit Progression of Oral Cancer by Down- Regulation of Matrix Methaloproteinase 2 Expression in Vivo.
Neoplasm Metastasis
Organ heterogeneity of host-derived matrix metalloproteinase expression and its involvement in multiple-organ metastasis by lung cancer cell lines.
Neoplasm Metastasis
Ornithine decarboxylase, mitogen-activated protein kinase and matrix metalloproteinase-2 expressions in human colon tumors.
Neoplasm Metastasis
Osteoclast-derived matrix metalloproteinase-7, but not matrix metalloproteinase-9, contributes to tumor-induced osteolysis.
Neoplasm Metastasis
Osteopontin promotes hepatocellular carcinoma invasion by up-regulating MMP-2 and uPA expression.
Neoplasm Metastasis
Osteoprotegerin expression in triple-negative breast cancer cells promotes metastasis.
Neoplasm Metastasis
Overexpression of eIF4E in colorectal cancer patients is associated with liver metastasis.
Neoplasm Metastasis
Overexpression of matrix metalloproteinase-2 and tissue inhibitor of matrix metalloproteinase-2 in liver from patients with gastrointestinal adenocarcinoma and no detectable metastasis.
Neoplasm Metastasis
Overexpression of MMP-2 and MMP-9 in esophageal squamous cell carcinoma.
Neoplasm Metastasis
Overexpression of myeloid zinc finger 1 suppresses matrix metalloproteinase-2 expression and reduces invasiveness of SiHa human cervical cancer cells.
Neoplasm Metastasis
Overexpression of protein kinase C-alpha and -beta isozymes by stromal dendritic cells in basal and squamous cell carcinoma.
Neoplasm Metastasis
Overexpression of Rab40b Promotes Hepatocellular Carcinoma Cell Proliferation and Metastasis via PI3K/AKT Signaling Pathway.
Neoplasm Metastasis
Overexpression of RCC2 Enhances Cell Motility and Promotes Tumor Metastasis in Lung Adenocarcinoma by Inducing Epithelial-Mesenchymal Transition.
Neoplasm Metastasis
Overexpression of tissue inhibitor of matrix metalloproteinases-1 (TIMP-1) in metastatic MDCK cells transformed by v-src.
Neoplasm Metastasis
Oxalomalate suppresses metastatic melanoma through IDH-targeted stress response to ROS.
Neoplasm Metastasis
Oxytocin inhibits ovarian cancer metastasis by repressing the expression of MMP-2 and VEGF.
Neoplasm Metastasis
p16 inhibits matrix metalloproteinase-2 expression via suppression of Sp1-mediated gene transcription.
Neoplasm Metastasis
p202, an interferon-inducible protein, mediates multiple antitumor activities in human pancreatic cancer xenograft models.
Neoplasm Metastasis
p21-activated protein kinase 1 induces the invasion of gastric cancer cells through c-Jun NH2-terminal kinase-mediated activation of matrix metalloproteinase-2.
Neoplasm Metastasis
p37 from Mycoplasma hyorhinis promotes cancer cell invasiveness and metastasis through activation of MMP-2 and followed by phosphorylation of EGFR.
Neoplasm Metastasis
Pancreatic Stellate Cells Activation and Matrix Metallopeptidase 2 Expression Correlate With Lymph Node Metastasis in Pancreatic Carcinoma.
Neoplasm Metastasis
Pathological and prognostic significance of matrix metalloproteinase-2 expression in ovarian cancer: a meta-analysis.
Neoplasm Metastasis
Patients with hepatic breast cancer metastases demonstrate highly specific profiles of matrix metalloproteinases MMP-2 and MMP-9 after SIRT treatment as compared to other primary and secondary liver tumours.
Neoplasm Metastasis
Peroxisome proliferator-activated receptor-? inhibits pancreatic cancer cell invasion and metastasis via regulating MMP-2 expression through PTEN.
Neoplasm Metastasis
Photodynamic effects on nasopharyngeal carcinoma (NPC) cells with 5-aminolevulinic acid or its hexyl ester.
Neoplasm Metastasis
Pigment epithelium-derived factor upregulates collagen I and downregulates matrix metalloproteinase 2 in osteosarcoma cells, and colocalises to collagen I and heat shock protein 47 in fetal and adult bone.
Neoplasm Metastasis
Pinostilbene Hydrate Suppresses Human Oral Cancer Cell Metastasis by Downregulation of Matrix Metalloproteinase-2 Through the Mitogen-Activated Protein Kinase Signaling Pathway.
Neoplasm Metastasis
PinX1 serves as a potential prognostic indicator for clear cell renal cell carcinoma and inhibits its invasion and metastasis by suppressing MMP-2 via NF-?B-dependent transcription.
Neoplasm Metastasis
Pituitary tumor-transforming 1 expression in laryngeal cancer and its association with prognosis.
Neoplasm Metastasis
Plantamajoside, a potential anti-tumor herbal medicine inhibits breast cancer growth and pulmonary metastasis by decreasing the activity of matrix metalloproteinase-9 and -2.
Neoplasm Metastasis
Plasma gelatinase levels in patients with primary breast cancer in relation to axillary lymph node status, Her2/neu expression and other clinicopathological variables.
Neoplasm Metastasis
Plasma MMP-2 and MMP-7 levels are elevated first month after surgery and may promote growth of residual metastases.
Neoplasm Metastasis
Platelet-activating factor mediates MMP-2 expression and activation via phosphorylation of cAMP-response element-binding protein and contributes to melanoma metastasis.
Neoplasm Metastasis
Positive and negative transcriptional elements of the human type IV collagenase gene.
Neoplasm Metastasis
Post-translational activation of Mmp2 correlates with patterns of active collagen degradation during the development of the zebrafish tail.
Neoplasm Metastasis
Potent anti-cancer effects of citrus peel flavonoids in human prostate xenograft tumors.
Neoplasm Metastasis
Potent tumor targeting drug release system comprising MMP-2 specific peptide fragment with self-assembling characteristics.
Neoplasm Metastasis
Pre-clinical investigation of STAT3 pathway in bladder cancer: Paving the way for clinical translation.
Neoplasm Metastasis
Predicting Novel Antitumor Agents: 3D-Pharmacophore Mapping of ?-N-biaryl Ether Sulfonamide-Based Hydroxamates as Potentially MMP-2 Inhibitors.
Neoplasm Metastasis
Prediction of metastasis in oral squamous cell carcinoma through phenotypic evaluation and gene expression of E-cadherin, ?-catenin, matrix metalloproteinase-2, and matrix metalloproteinase-9 biomarkers with clinical correlation.
Neoplasm Metastasis
Prediction of prognosis in gallbladder carcinoma by CD147 and MMP-2 immunohistochemistry.
Neoplasm Metastasis
Preferential digestion of basement membrane collagen by an enzyme derived from a metastatic murine tumor.
Neoplasm Metastasis
Preliminary evaluation of inhibition of matrix-metalloprotease MMP-2 and MMP-9 by Passiflora edulis and P foetida aqueous extracts.
Neoplasm Metastasis
Preoperative Serum Levels of Matrix Metalloproteinase-2 (MMP-2) and Survival of Breast Cancer among Korean Women.
Neoplasm Metastasis
Primary Ovarian Tumors With Lymphogenic and Hematogenic Metastasis Express High MMP-14, Which Colocalizes With Highly Sulfated Chondroitin Sulfate in the Stroma.
Neoplasm Metastasis
Pro-matrix metalloproteinase-2 transfection increases orthotopic primary growth and experimental metastasis of MDA-MB-231 human breast cancer cells in nude mice.
Neoplasm Metastasis
Production and characterization of a human single-chain Fv to collagenase IV.
Neoplasm Metastasis
Production of extracellular matrix-degrading proteinases by primary cultures of human epithelial ovarian carcinoma cells.
Neoplasm Metastasis
Production of matrix metalloproteinase-2 and metalloproteinase-3 related to malignant behavior of esophageal carcinoma. A clinicopathologic study.
Neoplasm Metastasis
Production of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human breast carcinomas.
Neoplasm Metastasis
Prognosis of metastasis based on age and serum analytes after follow-up of non-metastatic lung cancer patients.
Neoplasm Metastasis
Prognostic significance of circulating matrix metalloproteinase-2 to tissue inhibitor of metalloproteinases-2 ratio in recurrence of urothelial cancer after complete resection.
Neoplasm Metastasis
Prognostic Significance of Extracellular Matrix Metalloproteinase Inducer and Matrix Metalloproteinase 2 in Epithelial Ovarian Cancer.
Neoplasm Metastasis
Prognostic significance of matrix metalloproteinases 2 and 9 in bladder cancer.
Neoplasm Metastasis
Prognostic significance of matrix metalloproteinases-2 activation ratio in renal cell carcinoma.
Neoplasm Metastasis
Prognostic significance of phosphorylated signal transducer and activator of transcription 3 and suppressor of cytokine signaling 3 expression in human cutaneous melanoma.
Neoplasm Metastasis
Prognostic value of matrix metalloproteinase-2 (MMP-2) expression in endometrial endometrioid adenocarcinoma.
Neoplasm Metastasis
Prognostic value of matrix metalloproteinases (MMP-2 and MMP-9) in patients with lymph node-negative breast carcinoma.
Neoplasm Metastasis
Prognostic value of membrane type 1 and 2 matrix metalloproteinase expression and gelatinase A activity in bladder cancer.
Neoplasm Metastasis
Prognostic value of MMP-2 immunoreactive protein (72 kD type IV collagenase) in primary skin melanoma.
Neoplasm Metastasis
Prognostic values of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 expression in bladder cancer.
Neoplasm Metastasis
Progression of non-small cell lung cancer: diagnostic and prognostic utility of matrix metalloproteinase-2, C-reactive protein and serum amyloid A.
Neoplasm Metastasis
Promoter hypermethylation and silencing of tissue factor pathway inhibitor-2 in oral squamous cell carcinoma.
Neoplasm Metastasis
Protein expression of matrix metalloproteinases 2 and 9 and tissue inhibitors of metalloproteinase 1 and 2 in papillary thyroid carcinomas.
Neoplasm Metastasis
Proteolytic enzymes in tumor metastasis. II. Collagenase type IV activity in subcellular fractions of cloned tumor cell populations.
Neoplasm Metastasis
Proteolytic imbalance is reversed after therapeutic surgery in breast cancer patients.
Neoplasm Metastasis
Proteome analysis identified the PPAR? ligand 15d-PGJ2 as a novel drug inhibiting melanoma progression and interfering with tumor-stroma interaction.
Neoplasm Metastasis
Protocatechuic acid inhibits cancer cell metastasis involving the down-regulation of Ras/Akt/NF-?B pathway and MMP-2 production by targeting RhoB activation.
Neoplasm Metastasis
Psychological Stress Up-Regulates CD147 Expression Through Beta-Arrestin1/ERK to Promote Proliferation and Invasiveness of Glioma Cells.
Neoplasm Metastasis
PTEN and TRAIL genes loaded zein nanoparticles as potential therapy for hepatocellular carcinoma.
Neoplasm Metastasis
Purification and characterization of catalytic domains of gelatinase A with or without fibronectin insert for high-throughput inhibitor screening.
Neoplasm Metastasis
Qingyihuaji Formula Inhibits Progress of Liver Metastases From Advanced Pancreatic Cancer Xenograft by Targeting to Decrease Expression of Cyr61 and VEGF.
Neoplasm Metastasis
Quantum dots based molecular beacons for in vitro and in vivo detection of MMP-2 on tumor.
Neoplasm Metastasis
Rac1 mediates type I collagen-dependent MMP-2 activation. role in cell invasion across collagen barrier.
Neoplasm Metastasis
Raf kinase inhibitor protein suppresses nuclear factor-?B-dependent cancer cell invasion through negative regulation of matrix metalloproteinase expression.
Neoplasm Metastasis
Ratio of metalloproteinase 2 to tissue inhibitor of metalloproteinase 2 in medullary thyroid carcinoma.
Neoplasm Metastasis
Ratiometric Imaging of MMP-2 Activity Facilitates Tumor Detection Using Activatable Near-Infrared Fluorescent Semiconducting Polymer Nanoparticles.
Neoplasm Metastasis
Realgar Nanoparticles Inhibit Migration, Invasion and Metastasis in a Mouse Model of Breast Cancer by Suppressing Matrix Metalloproteinases and Angiogenesis.
Neoplasm Metastasis
Recent opportunities in matrix metalloproteinase inhibitor drug design for cancer.
Neoplasm Metastasis
Recombinant human prothrombin kringle-2 inhibits B16F10 melanoma metastasis through inhibition of neovascularization and reduction of matrix metalloproteinase expression.
Neoplasm Metastasis
Recombinant viral protein promotes apoptosis and suppresses invasion of ovarian adenocarcinoma cells by targeting ?5?1 integrin to downregulate Akt and MMP-2.
Neoplasm Metastasis
Red ginseng extract reduced metastasis of colon cancer cells in vitro and in vivo.
Neoplasm Metastasis
Redox state of adipose tissue for patients with gastric cancer and its connection with the body mass index and distance from the tumor.
Neoplasm Metastasis
Reduced expression of tissue inhibitor of metalloproteinase in nodal metastasis of stomach cancer.
Neoplasm Metastasis
Reduction of in vivo tumor growth by MMI-166, a selective matrix metalloproteinase inhibitor, through inhibition of tumor angiogenesis in squamous cell carcinoma cell lines of head and neck.
Neoplasm Metastasis
Reduction of metastasis, cell invasion, and adhesion in mouse osteosarcoma by YM529/ONO-5920-induced blockade of the Ras/MEK/ERK and Ras/PI3K/Akt pathway.
Neoplasm Metastasis
Regulation of 92-kD gelatinase release in HL-60 leukemia cells: tumor necrosis factor-alpha as an autocrine stimulus for basal- and phorbol ester-induced secretion.
Neoplasm Metastasis
Regulation of angiogenesis and invasion by human Pituitary tumor transforming gene (PTTG) through increased expression and secretion of matrix metalloproteinase-2 (MMP-2).
Neoplasm Metastasis
Regulation of angiostatin production by matrix metalloproteinase-2 in a model of concomitant resistance.
Neoplasm Metastasis
Regulation of gelatinase production in metastatic renal cell carcinoma by organ-specific fibroblasts.
Neoplasm Metastasis
Regulation of MMP-1 and MMP-2 production through CD147/extracellular matrix metalloproteinase inducer interactions.
Neoplasm Metastasis
Regulation of MT1-MMP and MMP-2 by the serpin PEDF: a promising new target for metastatic cancer.
Neoplasm Metastasis
Regulation of the Mr 72,000 type IV collagenase by the type I insulin-like growth factor receptor.
Neoplasm Metastasis
Relation of enhanced secretion of active matrix metalloproteinases with tumor spread in human hepatocellular carcinoma.
Neoplasm Metastasis
Relationship between expression of matrix metalloproteinase-2 and matrix metalloproteinase-9 and invasion ability of cervical cancer cells.
Neoplasm Metastasis
Relationship between matrix metalloproteinase-2 mRNA expression and clinicopathological and urokinase-type plasminogen activator system parameters and prognosis in human gastric cancer.
Neoplasm Metastasis
Relationship between protein expression of VEGF-C, MMP-2 and lymph node metastasis in papillary thyroid cancer.
Neoplasm Metastasis
Relationships between the level of matrix metalloproteinase-2 and tumor size of breast cancer.
Neoplasm Metastasis
Release of gelatinase A (matrix metalloproteinase 2) induced by photolysis of caged phosphatidic acid in HT 1080 metastatic fibrosarcoma cells.
Neoplasm Metastasis
Repression of 92-kDa type IV collagenase expression by MTA1 is mediated through direct interactions with the promoter via a mechanism, which is both dependent on and independent of histone deacetylation.
Neoplasm Metastasis
Resistin promotes tumor metastasis by down-regulation of miR-519d through the AMPK/p38 signaling pathway in human chondrosarcoma cells.
Neoplasm Metastasis
Resveratrol inhibits migration and invasion of human breast-cancer cells.
Neoplasm Metastasis
Resveratrol Inhibits the Epithelial-Mesenchymal Transition of Pancreatic Cancer Cells Via Suppression of the PI-3K/Akt/NF-?B Pathway.
Neoplasm Metastasis
Retroviral delivery of TIMP-2 inhibits H-ras-induced migration and invasion in MCF10A human breast epithelial cells.
Neoplasm Metastasis
RNAi targeting urokinase-type plasminogen activator receptor inhibits metastasis and progression of oral squamous cell carcinoma in vivo.
Neoplasm Metastasis
Rock2 promotes the invasion and metastasis of hepatocellular carcinoma by modifying MMP2 ubiquitination and degradation.
Neoplasm Metastasis
Role of extracellular matrix in breast cancer development: a brief update.
Neoplasm Metastasis
Role of GPER on proliferation, migration and invasion in ligand-independent manner in human ovarian cancer cell line SKOV3.
Neoplasm Metastasis
Role of interleukin 10 and transforming growth factor beta1 in the angiogenesis and metastasis of human prostate primary tumor lines from orthotopic implants in severe combined immunodeficiency mice.
Neoplasm Metastasis
Role of L1 cell adhesion molecule (L1CAM) in the metastatic cascade: promotion of dissemination, colonization, and metastatic growth.
Neoplasm Metastasis
Role of matrix metalloproteinase-9 in in vitro invasion of esophageal carcinoma cells.
Neoplasm Metastasis
Role of serum matrix metalloproteinase-2 and -9 to predict breast cancer progression.
Neoplasm Metastasis
Roles of microsomal prostaglandin E synthase-1 in lung metastasis formation in prostate cancer RM9 cells.
Neoplasm Metastasis
Rubus idaeus extract suppresses migration and invasion of human oral cancer by inhibiting MMP-2 through modulation of the Erk1/2 signaling pathway.
Neoplasm Metastasis
RUNX3 Inhibits the Invasion and Metastasis of Human Colon Cancer HT-29 Cells by Upregulating MMP-2/9.
Neoplasm Metastasis
Ruscogenin suppressed the hepatocellular carcinoma metastasis via PI3K/Akt/mTOR signaling pathway.
Neoplasm Metastasis
S-adenosylmethionine, a methyl donor, up regulates tissue inhibitor of metalloproteinase-2 in colorectal cancer.
Neoplasm Metastasis
S100A4 antisense oligodeoxynucleotide suppresses invasive potential of neuroblastoma cells.
Neoplasm Metastasis
S100A4 mediated cell invasion and metastasis of esophageal squamous cell carcinoma via the regulation of MMP-2 and E-cadherin activity.
Neoplasm Metastasis
S100A4 regulates membrane induced activation of matrix metalloproteinase-2 in osteosarcoma cells.
Neoplasm Metastasis
Salinomycin suppresses TGF-?1-induced epithelial-to-mesenchymal transition in MCF-7 human breast cancer cells.
Neoplasm Metastasis
SB225002 inhibits prostate cancer invasion and attenuates the expression of BSP, OPN and MMP?2.
Neoplasm Metastasis
Sea cucumber extract TBL-12 inhibits the proliferation, migration, and invasion of human prostate cancer cells through the p38 mitogen-activated protein kinase and intrinsic caspase apoptosis pathway.
Neoplasm Metastasis
Secretion and Expression of Matrix Metalloproteinase-2 and 9 from Bone Marrow Mononuclear Cells in Myelodysplastic Syndrome and Acute Myeloid Leukemia.
Neoplasm Metastasis
Secretion of extracellular hsp90alpha via exosomes increases cancer cell motility: a role for plasminogen activation.
Neoplasm Metastasis
Secretome protein signature of human pancreatic cancer stem-like cells.
Neoplasm Metastasis
Secretory leukocyte protease inhibitor is associated with MMP-2 and MMP-9 to promote migration and invasion in SNU638 gastric cancer cells.
Neoplasm Metastasis
Selection of invasive and metastatic subpopulations from a heterogeneous human melanoma cell line.
Neoplasm Metastasis
Selective non-zinc binding MMP-2 inhibitors: Novel benzamide Ilomastat analogs with anti-tumor metastasis.
Neoplasm Metastasis
Self-assembled nanomedicine combining a berberine derivative and doxorubicin for enhanced antitumor and antimetastatic efficacy via mitochondrial pathways.
Neoplasm Metastasis
Senescent fibroblasts enhance early skin carcinogenic events via a paracrine MMP-PAR-1 axis.
Neoplasm Metastasis
Seprase, a membrane-type serine protease, has different expression patterns in intestinal- and diffuse-type gastric cancer.
Neoplasm Metastasis
SERPINA3 Silencing Inhibits the Migration, Invasion, and Liver Metastasis of Colon Cancer Cells.
Neoplasm Metastasis
Serum and plasma M(r) 92,000 progelatinase levels correlate with spontaneous metastasis of rat 13762NF mammary adenocarcinoma.
Neoplasm Metastasis
Serum levels and tissue expression of matrix metalloproteinase 2 (MMP-2) and tissue inhibitor of metalloproteinases 2 (TIMP-2) in colorectal cancer patients.
Neoplasm Metastasis
Serum levels of matrix metalloproteinase-2 and -9 and conventional tumor markers (CEA and CA 19-9) in patients with colorectal and gastric cancers.
Neoplasm Metastasis
Serum levels of matrix metalloproteinase-9 predict lymph node metastasis in breast cancer patients.
Neoplasm Metastasis
Serum matrix metalloproteinase-2 and its density in men with prostate cancer as a new predictor of disease extension.
Neoplasm Metastasis
Serum metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in lung carcinoma patients.
Neoplasm Metastasis
Serum MMP-2 as a potential predictive marker for papillary thyroid carcinoma.
Neoplasm Metastasis
Shikonin inhibits prostate cancer cells metastasis by reducing matrix metalloproteinase-2/-9 expression via AKT/mTOR and ROS/ERK1/2 pathways.
Neoplasm Metastasis
ShRNA knock-down of CXCR7 inhibits tumour invasion and metastasis in hepatocellular carcinoma after transcatheter arterial chemoembolization.
Neoplasm Metastasis
Significance of serum type IV collagenolytic activities and gelatinase levels for detection of metastasis in murine RCT sarcoma.
Neoplasm Metastasis
Silence of ?1-Antitrypsin Inhibits Migration and Proliferation of Triple Negative Breast Cancer Cells.
Neoplasm Metastasis
Silencing cAMP-response element-binding protein (CREB) identifies CYR61 as a tumor suppressor gene in melanoma.
Neoplasm Metastasis
Silencing expression of the NANOG gene and changes in migration and metastasis of urinary bladder cancer cells.
Neoplasm Metastasis
Silencing of LASS2/TMSG1 enhances invasion and metastasis capacity of prostate cancer cell.
Neoplasm Metastasis
Silencing of TMSG1 enhances metastasis capacity by targeting V-ATPase in breast cancer.
Neoplasm Metastasis
Silibinin inhibits prostate cancer invasion, motility and migration by suppressing vimentin and MMP-2 expression.
Neoplasm Metastasis
Silibinin inhibits the invasion of human lung cancer cells via decreased productions of urokinase-plasminogen activator and matrix metalloproteinase-2.
Neoplasm Metastasis
Silibinin inhibits triple negative breast cancer cell motility by suppressing TGF-?2 expression.
Neoplasm Metastasis
Sinulariolide Suppresses Human Hepatocellular Carcinoma Cell Migration and Invasion by Inhibiting Matrix Metalloproteinase-2/-9 through MAPKs and PI3K/Akt Signaling Pathways.
Neoplasm Metastasis
Social defeat stress promotes tumor growth and angiogenesis by upregulating vascular endothelial growth factor/extracellular signal-regulated kinase/matrix metalloproteinase signaling in a mouse model of lung carcinoma.
Neoplasm Metastasis
Solanine induces mitochondria-mediated apoptosis in human pancreatic cancer cells.
Neoplasm Metastasis
Solution structure and backbone dynamics of the catalytic domain of matrix metalloproteinase-2 complexed with a hydroxamic acid inhibitor.
Neoplasm Metastasis
Somatostatin Octapeptide Inhibits Cell Invasion and Metastasis in Hepatocellular Carcinoma Through PEBP1.
Neoplasm Metastasis
Soybean saponin inhibits tumor cell metastasis by modulating expressions of MMP-2, MMP-9 and TIMP- 2.
Neoplasm Metastasis
SPAG5 promotes osteosarcoma metastasis via activation of FOXM1/MMP2 axis.
Neoplasm Metastasis
SPARC is associated with gastric cancer progression and poor survival of patients.
Neoplasm Metastasis
Specific interaction between chitosan and matrix metalloprotease 2 decreases the invasive activity of human melanoma cells.
Neoplasm Metastasis
Spermidine inhibits MMP-2 via modulation of histone acetyltransferase and histone deacetylase in HDFs.
Neoplasm Metastasis
Spreds, inhibitors of the Ras/ERK signal transduction, are dysregulated in human hepatocellular carcinoma and linked to the malignant phenotype of tumors.
Neoplasm Metastasis
Stage-specific expression analysis ofMMP-2 & MMP-9 in laryngeal carcinoma.
Neoplasm Metastasis
Stat1 negatively regulates angiogenesis, tumorigenicity and metastasis of tumor cells.
Neoplasm Metastasis
Stat3 activation regulates the expression of matrix metalloproteinase-2 and tumor invasion and metastasis.
Neoplasm Metastasis
Stat3 Is Involved in Angiotensin II-Induced Expression of MMP2 in Gastric Cancer Cells.
Neoplasm Metastasis
Stimulation of matrix metalloproteinase-9 expression in human fibrosarcoma cells by synthetic matrix metalloproteinase inhibitors.
Neoplasm Metastasis
Stimulation of the 92-kD type IV collagenase promoter and enzyme expression in human melanoma cells.
Neoplasm Metastasis
Stromal cells as the major source for matrix metalloproteinase-2 in cutaneous melanoma.
Neoplasm Metastasis
Stromal matrix metalloproteinase 2 regulates collagen expression and promotes the outgrowth of experimental metastases.
Neoplasm Metastasis
Stromal-cell derived factor-1 regulates epithelial ovarian cancer cell invasion by activating matrix metalloproteinase-9 and matrix metalloproteinase-2.
Neoplasm Metastasis
Stromal-epithelial interaction in type IV collagenase expression and activation: The role in cancer metastasis.
Neoplasm Metastasis
Strong significant correlation between MMP-9 and systemic symptoms in patients with localized renal cell carcinoma.
Neoplasm Metastasis
Study on antitumor activities of the chrysin-chromene-spirooxindole on Lewis lung carcinoma C57BL/6 mice in vivo.
Neoplasm Metastasis
Sulforaphene Interferes with Human Breast Cancer Cell Migration and Invasion through Inhibition of Hedgehog Signaling.
Neoplasm Metastasis
Superoxide- and NO-dependent mechanisms of antitumor and antimetastatic effect of L-arginine hydrochloride and coenzyme Q10.
Neoplasm Metastasis
Suppression of gelatinase production with decreased invasiveness of choriocarcinoma cells by human recombinant interferon beta.
Neoplasm Metastasis
Suppression of lung cancer cell invasion and metastasis by connexin43 involves the secretion of follistatin-like 1 mediated via histone acetylation.
Neoplasm Metastasis
Suppression on metastasis by rhubarb through modulation on MMP-2 and uPA in human A549 lung adenocarcinoma: An ex vivo approach.
Neoplasm Metastasis
Suppressive effects of microRNA-16 on the proliferation, invasion and metastasis of hepatocellular carcinoma cells.
Neoplasm Metastasis
Suppressive Effects of Plumbagin on Invasion and Migration of Breast Cancer Cells via the Inhibition of STAT3 Signaling and Down-regulation of Inflammatory Cytokine Expressions.
Neoplasm Metastasis
Surfactin from Bacillus subtilis attenuates ambient air particulate matter-promoted human oral cancer cells metastatic potential.
Neoplasm Metastasis
Synergistic anticancer effects of timosaponin AIII and ginsenosides in MG63 human osteosarcoma cells.
Neoplasm Metastasis
Synthesis and evaluation of myxochelin analogues as antimetastatic agents.
Neoplasm Metastasis
Synthesis, structure and characterization of novel Cd(II) and Zn(II) complexes with the condensation product of 2-formylpyridine and selenosemicarbazide Antiproliferative activity of the synthesized complexes and related selenosemicarbazone complexes.
Neoplasm Metastasis
Synthesized tetrahydroisoquinoline alkaloid exerts anticancer effects at least in part by suppressing NF??B?regulated proteins in A549 human lung cancer cells.
Neoplasm Metastasis
Targeting angiogenic pathway for chemoprevention of experimental colon cancer using C-phycocyanin as cyclooxygenase-2 inhibitor.
Neoplasm Metastasis
Targeting melanoma growth and metastasis with systemic delivery of liposome-incorporated protease-activated receptor-1 small interfering RNA.
Neoplasm Metastasis
Targeting of colorectal cancer growth, metastasis, and anti-apoptosis in BALB/c nude mice via APRIL siRNA.
Neoplasm Metastasis
Targeting the MMP-14/MMP-2/integrin ?v?3 axis with multispecific N-TIMP2-based antagonists for cancer therapy.
Neoplasm Metastasis
Targeting the molecular chaperone heat shock protein 90 (HSP90): Lessons learned and future directions.
Neoplasm Metastasis
Tetraspanin CD9 induces MMP-2 expression by activating p38 MAPK, JNK and c-Jun pathways in human melanoma cells.
Neoplasm Metastasis
TGF-?1 increases invasiveness of SW1990 cells through Rac1/ROS/NF-?B/IL-6/MMP-2.
Neoplasm Metastasis
TGF-?1 inhibits the growth and metastasis of tongue squamous carcinoma cells through Smad4.
Neoplasm Metastasis
TGF-beta1 promotes liver metastasis of pancreatic cancer by modulating the capacity of cellular invasion.
Neoplasm Metastasis
The a3 Isoform Vacuolar Type H+-ATPase Promotes Distant Metastasis in the Mouse B16 Melanoma Cells.
Neoplasm Metastasis
The AIB1 oncogene promotes breast cancer metastasis by activation of PEA3-mediated matrix metalloproteinase 2 (MMP2) and MMP9 expression.
Neoplasm Metastasis
The anti-alcohol dependency drug disulfiram inhibits the viability and progression of gastric cancer cells by regulating the Wnt and NF-?B pathways.
Neoplasm Metastasis
The Anti-tumoral Effect of ?-D-Mannuronic Acid (M2000) as a Novel NSAID on Treg Cells Frequency and MMP-2, MMP-9, CCL22 and TGF?1 Gene Expression in Pre-surgical Breast Cancer Patients.
Neoplasm Metastasis
The assessment of serum and diagnostic peritoneal lavage concentration of matrix metalloproteinase-2, matrix metalloproteinase-9, carbohydrate antigen 19-9, and carcinoembryonic antigen in patients with pancreatic cancer and chronic pancreatitis.
Neoplasm Metastasis
The C3G/Rap1 pathway promotes secretion of MMP-2 and MMP-9 and is involved in serous ovarian cancer metastasis.
Neoplasm Metastasis
The collagenase activities, interstitial collagenase and type IV collagenase, in human stomach cancer: with special reference to local spreading and lymph node metastasis.
Neoplasm Metastasis
The combination of sorafenib and radiation preferentially inhibits breast cancer stem cells by suppressing HIF-1? expression.
Neoplasm Metastasis
The correlation between immunohistochemical expression of MMP-2 and the prognosis of epithelial ovarian cancer.
Neoplasm Metastasis
The E2 protein of human papillomavirus type 8 increases the expression of matrix metalloproteinase-9 in human keratinocytes and organotypic skin cultures.
Neoplasm Metastasis
The effect of dietary supplementation with limonene or myo-inositol on the induction of neoplasia and matrix metalloproteinase and plasminogen activator activities in accessory sex organs of male Lobund-Wistar rats.
Neoplasm Metastasis
The effect of PI3K inhibitor LY294002 and gemcitabine hydrochloride combined with ionizing radiation on the formation of vasculogenic mimicry of Panc-1 cells in vitro and in vivo.
Neoplasm Metastasis
The enamel matrix derivative (Emdogain) enhances human tongue carcinoma cells gelatinase production, migration and metastasis formation.
Neoplasm Metastasis
The expression and clinical significance of metastasis suppressor gene and matrix metalloproteinase-2 in esophageal squamous cell of carcinoma.
Neoplasm Metastasis
The expression and significance of AKR1B10 in laryngeal squamous cell carcinoma.
Neoplasm Metastasis
The expression of MMP-2 and TIMP-2 in patients with colorectal adenocarcinoma invaded to the submucosal and proper muscle layer.
Neoplasm Metastasis
The expression of MMP-2 and TIMP-2 in patients with primary colorectal adenocarcinoma: correlation with liver metastasis.
Neoplasm Metastasis
The extracellular matrix produced by bovine corneal endothelial cells contains progelatinase A.
Neoplasm Metastasis
The growth and metastasis of human hepatocellular carcinoma xenografts are inhibited by small interfering RNA targeting to the subunit ATP6L of proton pump.
Neoplasm Metastasis
The Immunohistochemical Expression of STAT3, Bcl-xL, and MMP-2 Proteins in Colon Adenoma and Adenocarcinoma.
Neoplasm Metastasis
The impact of a chlorotoxin-modified liposome system on receptor MMP-2 and the receptor-associated protein ClC-3.
Neoplasm Metastasis
The impact of matrix metalloproteinase 2 on prognosis and clinicopathology of breast cancer patients: a systematic meta-analysis.
Neoplasm Metastasis
The In Ovo Chick Chorioallantoic Membrane (CAM) Assay as an Efficient Xenograft Model of Hepatocellular Carcinoma.
Neoplasm Metastasis
The influence of MMP-14, TIMP-2 and MMP-2 expression on breast cancer prognosis.
Neoplasm Metastasis
The influence of vascular endothelial growth factor-A and matrix metalloproteinase-2 and -9 in angiogenesis, metastasis, and prognosis of endometrial cancer.
Neoplasm Metastasis
The initial steps of ovarian cancer cell metastasis are mediated by MMP-2 cleavage of vitronectin and fibronectin.
Neoplasm Metastasis
The insulin-like growth factor-I receptor inhibitor picropodophyllin causes tumor regression and attenuates mechanisms involved in invasion of uveal melanoma cells.
Neoplasm Metastasis
The leukotriene B4 receptor-2 promotes invasiveness and metastasis of ovarian cancer cells through STAT3-dependent up-regulation of matrix metalloproteinase 2.
Neoplasm Metastasis
The metallo-disintegrin ADAM10 (MADM) from bovine kidney has type IV collagenase activity in vitro.
Neoplasm Metastasis
The p75(NTR) metastasis suppressor inhibits urokinase plasminogen activator, matrix metalloproteinase-2 and matrix metalloproteinase-9 in PC-3 prostate cancer cells.
Neoplasm Metastasis
The ratio of MMP-2 to TIMP-2 in hilar cholangiocarcinoma: a semi-quantitative study.
Neoplasm Metastasis
The relation of gelatinase (MMP-2 and -9) expression with distant site metastasis and tumour aggressiveness in colorectal cancer.
Neoplasm Metastasis
The relationship between MMP-2 and MMP-9 expression levels with breast cancer incidence and prognosis.
Neoplasm Metastasis
The relevance and role of vascular endothelial growth factor C, matrix metalloproteinase-2 and E-cadherin in epithelial ovarian cancer.
Neoplasm Metastasis
The role of gelatinases in colorectal cancer progression and metastasis.
Neoplasm Metastasis
The role of matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) in the development of esophageal cancer.
Neoplasm Metastasis
The Role of Matrix Metalloproteinases in the Epithelial-Mesenchymal Transition of Hepatocellular Carcinoma.
Neoplasm Metastasis
The role of matrix metalloproteinases in tumor angiogenesis and tumor metastasis.
Neoplasm Metastasis
The role of MMP-2 and MMP-9 as prognostic markers in the early stages of tongue squamous cell carcinoma.
Neoplasm Metastasis
The role of MMP-2 and MMP-9 in the metastasis and development of hypopharyngeal carcinoma.
Neoplasm Metastasis
The role of p53 protein and MMP-2 tumor/stromal cells expression on progressive growth of ovarian neoplasms.
Neoplasm Metastasis
The role of the activated form of matrix metalloproteinase-2 in urothelial cancer.
Neoplasm Metastasis
The significance of MMP-1 and MMP-2 in peritoneal disseminated metastasis of gastric cancer.
Neoplasm Metastasis
The Target Differences of Anti-Tumorigenesis Potential of Curcumin and its Analogues Against HER-2 Positive and Triple-Negative Breast Cancer Cells.
Neoplasm Metastasis
Therapeutic and analysis model of intrahepatic metastasis reflects clinical behavior of hepatocellular carcinoma.
Neoplasm Metastasis
Therapeutic effects of tyroserleutide on lung metastasis of human hepatocellular carcinoma SK-HEP-1 and its mechanism affecting ICAM-1 and MMP-2 and -9.
Neoplasm Metastasis
Thrombospondin-2 promotes prostate cancer bone metastasis by the up-regulation of matrix metalloproteinase-2 through down-regulating miR-376c expression.
Neoplasm Metastasis
Thymoquinone inhibited vasculogenic capacity and promoted mesenchymal-epithelial transition of human breast cancer stem cells.
Neoplasm Metastasis
Thymoquinone inhibits metastasis of renal cell carcinoma cell 786-O-SI3 associating with downregulation of MMP-2 and u-PA and suppression of PI3K/Src signaling.
Neoplasm Metastasis
TIMP-1 overexpression in pancreatic cancer attenuates tumor growth, decreases implantation and metastasis, and inhibits angiogenesis.
Neoplasm Metastasis
TIMP-2 gene rs4789936 polymorphism is associated with increased risk of breast cancer and poor prognosis in Southern Chinese women.
Neoplasm Metastasis
TIMP-2 over-expression reduces invasion and angiogenesis and protects B16F10 melanoma cells from apoptosis.
Neoplasm Metastasis
Tissue inhibitor of metalloproteinase 3 suppresses tumor angiogenesis in matrix metalloproteinase 2-down-regulated lung cancer.
Neoplasm Metastasis
Tissue levels of active matrix metalloproteinase-2 and -9 in colorectal cancer.
Neoplasm Metastasis
TM4SF1 Regulates Pancreatic Cancer Migration and Invasion In Vitro and In Vivo.
Neoplasm Metastasis
Tomatidine inhibits cell invasion through the negative modulation of gelatinase and inactivation of p38 and ERK.
Neoplasm Metastasis
TPX2 silencing mediated by joint action of microvesicles and ultrasonic radiation inhibits the migration and invasion of SKOV3 cells.
Neoplasm Metastasis
Transcriptional activation of the matrix metalloproteinase-9 gene in an H-ras and v-myc transformed rat embryo cell line.
Neoplasm Metastasis
Transcriptional Repressor Snail and Metastasis in Hepatocellular Carcinoma.
Neoplasm Metastasis
Transcriptional suppression of matrix metalloproteinase-2 gene expression in human astroglioma cells by TNF-alpha and IFN-gamma.
Neoplasm Metastasis
Transcutaneous carbon dioxide induces mitochondrial apoptosis and suppresses metastasis of oral squamous cell carcinoma in vivo.
Neoplasm Metastasis
Transfection of nm23-H1 increased expression of beta-Catenin, E-Cadherin and TIMP-1 and decreased the expression of MMP-2, CD44v6 and VEGF and inhibited the metastatic potential of human non-small cell lung cancer cell line L9981.
Neoplasm Metastasis
Transforming growth factor beta1 stimulates contrasting responses in metastatic versus primary mouse prostate cancer-derived cell lines in vitro.
Neoplasm Metastasis
Treatment of colorectal liver metastases by adenoviral transfer of tissue inhibitor of metalloproteinases-2 into the liver tissue.
Neoplasm Metastasis
Trichostatin A-histone deacetylase inhibitor with clinical therapeutic potential-is also a selective and potent inhibitor of gelatinase A expression.
Neoplasm Metastasis
Tumor metastasis in an orthotopic murine model of head and neck cancer: possible role of TGF-beta 1 secreted by the tumor cells.
Neoplasm Metastasis
Tumor progression driven by pathways activating matrix metalloproteinases and their inhibitors.
Neoplasm Metastasis
Tumor-elicited polymorphonuclear cells, in contrast to "normal" circulating polymorphonuclear cells, stimulate invasive and metastatic potentials of rat mammary adenocarcinoma cells.
Neoplasm Metastasis
Tumour metastasis suppressor, nm23-beta, inhibits gelatinase A transcription by interference with transactivator Y-box protein-1 (YB-1).
Neoplasm Metastasis
Tumour-associated fibrinolysis: the prognostic relevance of plasminogen activators uPA and tPA in human breast cancer.
Neoplasm Metastasis
Type I collagen-induced pro-MMP-2 activation is differentially regulated by H-Ras and N-Ras in human breast epithelial cells.
Neoplasm Metastasis
Type IV collagen, type IV collagenase activity and ability of cell proliferation in human thyroid tumours.
Neoplasm Metastasis
Type IV collagenase (matrix metalloproteinase-2 and -9) in prostate cancer.
Neoplasm Metastasis
Type IV collagenase activity of a primary HSV-2-induced hamster fibrosarcoma and its in vivo metastases and in vitro clones.
Neoplasm Metastasis
Type IV collagenase and immunostaining of type IV collagen in human thyroid tumors.
Neoplasm Metastasis
Unconjugated Bilirubin Is a Novel Prognostic Biomarker for Nasopharyngeal Carcinoma and Inhibits Its Metastasis via Antioxidation Activity.
Neoplasm Metastasis
Up-regulation of gelatinases in the colorectal adenoma-carcinoma sequence.
Neoplasm Metastasis
Upregulated EMMPRIN/CD147 might contribute to growth and angiogenesis of gastric carcinoma: a good marker for local invasion and prognosis.
Neoplasm Metastasis
Upregulated matrix metalloproteinase-2 and downregulated tissue factor pathway inhibitor-2 are risk factors for lymph node metastasis and perineural invasion in pancreatic carcinoma.
Neoplasm Metastasis
Upregulation of ARHGAP30 attenuates pancreatic cancer progression by inactivating the ?-catenin pathway.
Neoplasm Metastasis
Upregulation of histamine receptor H1 promotes tumor progression and contributes to poor prognosis in hepatocellular carcinoma.
Neoplasm Metastasis
Upregulation of miR-328 and inhibition of CREB-DNA-binding activity are critical for resveratrol-mediated suppression of matrix metalloproteinase-2 and subsequent metastatic ability in human osteosarcomas.
Neoplasm Metastasis
Use of plasma MMP-2 and MMP-9 levels as a surrogate for tumour expression in colorectal cancer patients.
Neoplasm Metastasis
Using caffeoyl pyrrolidine derivative LY52, a potential inhibitor of matrix metalloproteinase-2, to suppress tumor invasion and metastasis.
Neoplasm Metastasis
Uterine cervical carcinoma: Role of matrix metalloproteinases (Review).
Neoplasm Metastasis
Vascular endothelial growth factor-C expression and invasive phenotype in ovarian carcinomas.
Neoplasm Metastasis
Vemurafenib resistance increases melanoma invasiveness and modulates the tumor microenvironment by MMP-2 upregulation.
Neoplasm Metastasis
Video-rate bioluminescence imaging of matrix metalloproteinase-2 secreted from a migrating cell.
Neoplasm Metastasis
Vinorelbine cationic liposomes modified with wheat germ agglutinin for inhibiting tumor metastasis in treatment of brain glioma.
Neoplasm Metastasis
Violacein inhibits matrix metalloproteinase mediated CXCR4 expression: potential anti-tumor effect in cancer invasion and metastasis.
Neoplasm Metastasis
Visfatin Promotes the Metastatic Potential of Chondrosarcoma Cells by Stimulating AP-1-Dependent MMP-2 Production in the MAPK Pathway.
Neoplasm Metastasis
WFDC2 contributes to epithelial-mesenchymal transition (EMT) by activating AKT signaling pathway and regulating MMP-2 expression.
Neoplasm Metastasis
Wip1 is associated with tumorigenity and metastasis through MMP-2 in human intrahepatic cholangiocarcinoma.
Neoplasm Metastasis
Wnt signaling pathway inhibitors as promising diagnostic serum markers of osteolytic bone metastasis.
Neoplasm Metastasis
Worse prognosis in breast cancer patients can be predicted by immunohistochemical analysis of positive MMP-2 and negative estrogen and progesterone receptors.
Neoplasm Metastasis
Xiao Han, et al., GHGKHKNK Octapeptide (P-5m) Inhibits Metastasis of HCCLM3 Cell Lines via Regulation of MMP-2 Expression in in Vitro and in Vivo Studies. Molecules, 2012, 17, 1357-1372.
Neoplasm Metastasis
XRCC1 serves as a potential prognostic indicator for clear cell renal cell carcinoma and inhibits its invasion and metastasis through suppressing MMP-2 and MMP-9.
Neoplasm Metastasis
Zn(2+) induces apoptosis in human highly metastatic SHG-44 glioma cells, through inhibiting activity of the voltage-gated proton channel Hv1.
Neoplasm Metastasis
ZNF139 promotes tumor metastasis by increasing migration and invasion in human gastric cancer cells.
Neoplasm Metastasis
Zoledronic acid exhibits inhibitory effects on osteoblastic and osteolytic metastases of prostate cancer.
Neoplasm Metastasis
Zymographic analysis of circulating and tissue forms of colon carcinoma gelatinase A (MMP-2) and B (MMP-9) separated by mono- and two-dimensional electrophoresis.
Neoplasm Metastasis
[An experimental research on tumor metastasis treated by chicken homologous matrix metalloproteinase-2 vaccine combined with low-dose cisplatin]
Neoplasm Metastasis
[Association of JMJD3, MMP-2 and VEGF expressions with clinicopathological features of invasive ductal breast carcinoma].
Neoplasm Metastasis
[Clinical significance and relationship of expression of matrix metalloproteinase-2 mRNA with breast cancer metastasis.]
Neoplasm Metastasis
[Clinical significance of matrix metalloproteinase-2 expression in patients with epithelial ovarian tumor]
Neoplasm Metastasis
[Construction and secretory expression of single-chain Fv fragment M97 with therapeutic potential against tumor invasion and metastasis]
Neoplasm Metastasis
[Correlation between expression of matrix metalloproteinase-2 and angiogenesis in esophageal carcinoma]
Neoplasm Metastasis
[Correlation between expression of metastasis-related genes and lymph node metastasis in testicular cancer]
Neoplasm Metastasis
[Correlation between expression of MMP-2, MMP-9, TIMP-2, TIMP-1 and metastasis of neuroblastoma]
Neoplasm Metastasis
[Correlation between matrix metalloproteinases-2 and tissue inhibitor of metalloproteinase-2 expression, metastatic potential and tumor angiogenesis in synovial sarcoma and its prognostic significance]
Neoplasm Metastasis
[Correlation of expression of vascular endothelial growth factor and matrix matalloproteinase-2 to invasion of ovarian tumor cells in vitro]
Neoplasm Metastasis
[Correlation of tenascin-C degradation fragment with recurrence and/or metastasis in early non-small-cell lung cancer]
Neoplasm Metastasis
[Correlations of serous levels of matrix metalloproteinases (MMP-2 and MMP-9) to invasion and metastasis of papillary thyroid carcinoma]
Neoplasm Metastasis
[Dynamic study on expression of gelatinase A and its natural inhibitor during invasion and metastasis of induced lung cancer in Wistar rats]
Neoplasm Metastasis
[Effect of cyclooxygenase-2,and matrix metalloproteinase-2 expression on prognosis of lung cancer]
Neoplasm Metastasis
[Effect of hypoxia on infiltration and migration of lung cancer cells and expression of MMP-2 and TIMP-2.]
Neoplasm Metastasis
[Effect of long noncoding RNA SPRY4-IT1 on proliferation and metastasis of medulloblastoma].
Neoplasm Metastasis
[Effect of RNAi-mediated STAT3 gene inhibition on metastasis of human pancreatic cancer cells]
Neoplasm Metastasis
[Effect of tumor-associated macrophages on invasion and metastasis of gastric cancer cells].
Neoplasm Metastasis
[Effects of dihydromyricetin on the migration and invasion of human gastric cancer MKN45 cells and its mechanism].
Neoplasm Metastasis
[Enhancement effects of hypoxia on invasion and metastasis of K562 cells]
Neoplasm Metastasis
[Expression and clinical significance of matrix metalloproteinase-2 in laryngeal squamous cell carcinoma]
Neoplasm Metastasis
[Expression and clinical significance of MMP-2, MMP-9,TIMP-1, and TIMP-2 in breast carcinoma]
Neoplasm Metastasis
[Expression and clinicopathologic significance of OPN, CD44v6 and MMP-2 in squamous cell carcinoma and adenocarcinoma of the lung].
Neoplasm Metastasis
[Expression and pathological mechanism of MMP-9 and HIF-2? in CD133(+) lung cancer stem cells].
Neoplasm Metastasis
[Expression of CD147, matrix metalloproteinases and transforming growth factor beta1 in breast cancer]
Neoplasm Metastasis
[Expression of FOXC-2 and YB-1 in Gastric Carcinoma and Its Role in Invasion and Metastasis].
Neoplasm Metastasis
[Expression of LOX and MMP-2 in gastric cancer tissue and the effects of LOX and MMP-2 on tumor invasion and metastasis].
Neoplasm Metastasis
[Expression of matrix metalloproteinase-2 and insulin-like growth factor-1 in gastric carcinoma and their clinicopathological significance].
Neoplasm Metastasis
[Expression of matrix metalloproteinase-2 in hypopharyngeal carcinoma and its clinical significance]
Neoplasm Metastasis
[Expression of matrix metalloproteinase-2, 9 and their inhibitor-TIMP 1,2 in human squamous cell carcinoma of uterine cervix]
Neoplasm Metastasis
[Expression of matrix metalloproteinase-2,9 in hypopharyngeal carcinoma and its relationship with lymphatic metastasis]
Neoplasm Metastasis
[Expression of matrix metalloproteinase-2,matrix metalloproteinase-9 and vascular endothdial growth factor in retinoblastoma and its clinical significance.]
Neoplasm Metastasis
[Expression of matrix metalloproteinases and tissue inhibitor of metalloproteinases in colorectal neoplasm]
Neoplasm Metastasis
[Expression of matrix metaloproteinase and tissue inhibitors in ovarian tumors]
Neoplasm Metastasis
[Expression of membrane-type matrix metalloproteinase (MT-MMP) and activation of MMP-2 in lung cancer]
Neoplasm Metastasis
[Expression of MMP-2 and E-CD in salivary mucoepidermoid carcinoma and its correlation with infiltration, metastasis and prognosis]
Neoplasm Metastasis
[Expression of MMP-2 and its clinical significance in cervical squamous carcinoma]
Neoplasm Metastasis
[Expression of MMP-2, MMP-9, TIMP-1 and their relationship with prognosis in NSCLC.]
Neoplasm Metastasis
[Expression of nm23/NDPK, integrin, type IV collagenase and uPA in transplanted tumors with various metastatic potential in nude mice and surgical specimens]
Neoplasm Metastasis
[Expression of TGF-beta1 and the mechanism of invasiveness and metastasis induced by TGF-beta1 in breast cancer]
Neoplasm Metastasis
[Expressions of CD147 and matrix metalloproteinase-2 in breast cancer and their correlations to prognosis]
Neoplasm Metastasis
[Expressions of CD147, MMP-2 and MMP-9 in laryngeal carcinoma and clinical significance]
Neoplasm Metastasis
[Expressions of COX-2 and MMP-2 in nasopharyngeal carcinoma and the their relationship with lymph node metastasis]
Neoplasm Metastasis
[Expressions of MMP-2 and COX-2 mRNA in bladder transitional cell carcinoma and their correlation]
Neoplasm Metastasis
[Expressions of vascular endothelial growth factor C and matrix metalloproteinases-2 and prognosis of non-small cell lung carcinoma.]
Neoplasm Metastasis
[FABP5 promotes cell growth, invasion and metastasis in cervical cancer].
Neoplasm Metastasis
[Gene expressions of type IV collagenase and tissue inhibitor of metalloproteinases (TIMP) in human bladder cancers]
Neoplasm Metastasis
[Helicobacter pylori infection, the invasion and metastasis of the gastric carcinoma, and the expression of MMP-2 and TIMP-2]
Neoplasm Metastasis
[Implication of VEGF and MMPs in hepatic metastasis of human colon cancer]
Neoplasm Metastasis
[Inhibitory effect of AG490 on invasion and metastasis of human pancreatic cancer cells in vitro]
Neoplasm Metastasis
[Inhibitory effect of endoplasmic reticulum-retained anti-type IV collagenase intrabody on invasion and proliferation of cancer cell]
Neoplasm Metastasis
[Inhibitory effects of matrix metalloproteinase (MMP) inhibitor LY52 on expression of MMP-2 and MMP-9 and invasive ability of human ovarian carcinoma cell line SKOV3]
Neoplasm Metastasis
[Key enzymes of degradation and angiogenesis as a factors of tumor progression in squamous cell carcinoma of the cervix].
Neoplasm Metastasis
[Matrix metalloproteinase 2 and 9 as the factor of head and neck tumor metastasis]
Neoplasm Metastasis
[Matrix metalloproteinase-2 concentrations in squamous cell carcinoma of the head and neck and its clinical significance]
Neoplasm Metastasis
[Matrix metalloproteinase-2 expression and its correlation with mesorectal metastasis in middle and lower rectal cancer]
Neoplasm Metastasis
[Metastatic ability and type IV collagenase expression of oncogene-transformed human bronchial epithelial cells]
Neoplasm Metastasis
[MMP-2/TIMP-2 expression in the trophoblasts of patients with gestational trophoblastic disease]
Neoplasm Metastasis
[Molecular biology studies on metalloproteinase and tissue inhibitor of metalloproteinase expression in salivary adenoid cystic carcinoma]
Neoplasm Metastasis
[Molecular mechanism of reversing metastatic phenotype in human high-metastatic large cell lung cancer cell line L9981 by nm23-H1]
Neoplasm Metastasis
[Prognostic value of serum MMP-2 level in uterine cancer affected women]
Neoplasm Metastasis
[Progress of clinical pathology and application of PET-CT on thyroid carcinoma]
Neoplasm Metastasis
[Promotion of MAG-1 on Metastasis of Lung Cancer Cells in vitro and Its Expression in Lung Cancer Tissue of 24 Cases.]
Neoplasm Metastasis
[Regulation of matrix-degrading enzymes in gynecologic cancer tissues and cells]
Neoplasm Metastasis
[Relationship between expression of MMP-2 and prognosis in human laryngeal squamous cell carcinoma].
Neoplasm Metastasis
[Relationship between serum matrix metalloproteinase-2 and metastasis and recurrence following radical hepatic resection in hepatocellular carcinoma]
Neoplasm Metastasis
[Role of matrix metalloproteinase (MMP)-2 and -9 and vascular endothelial growth factor C in lymph node metastasis of breast cancer.]
Neoplasm Metastasis
[Role of organ specific fibroblasts in metastasis of human renal cell carcinoma: regulation of type IV collagenase production from human renal cell carcinoma by organ specific fibroblasts]
Neoplasm Metastasis
[Role of type IV collagene and type IV collagenase in the invasion and metastasis of salivary adenoid cystic carcinoma]
Neoplasm Metastasis
[Short hairpin RNA-mediated suvivin gene silencing inhibits invasion and metastasis of human colon carcinoma cell line SW480 in vitro]
Neoplasm Metastasis
[Significance of caveolin-1 protein detected by quantum dots technique in human lung cancer invasiveness and metastasis.]
Neoplasm Metastasis
[SRC kinase inhibitor PP2 inhibits invasion and metastasis of lung cancer A549 cells by upregulating connexin43 expression].
Neoplasm Metastasis
[Study of matrix metalloproteinase-2 and -9 in thyroid papillary cancer]
Neoplasm Metastasis
[Study on expression of matrix metalloproteinases and their inhibitors in parotid gland tumors]
Neoplasm Metastasis
[The correlation between neck lymphy node metastasis and matrixmetalloproteinase-2 expression at the invasive tumor front of oral squamous cell carcinomas]
Neoplasm Metastasis
[The effects of MMPs and TIMPs on the metastasis of oral squamous cell carcinoma to neck lymph nodes]
Neoplasm Metastasis
[The expression and its clinical significance of MMP-2 and MMP-9 in non-small cell lung cancer.]
Neoplasm Metastasis
[The expression of matrix metalloproteinase-2 and -9 in cervical cancer and a study of their relationship]
Neoplasm Metastasis
[The expression of matrix metalloproteinases and tissue inhibitor of metalloproteinases in transplanted tumor of salivary adenoid cystic carcinoma cell lines]
Neoplasm Metastasis
[The expression of MMP-2, E-cadherin in supraglottic carcinoma and their relationship with cervical lymph nody metastasis]
Neoplasm Metastasis
[The matrix metalloproteinase in oral and oropharyngeol cancer - literature review].
Neoplasm Metastasis
[The mechanisms of microenvironments influence on vasculogenic mimicry between introcular and subcutaneous melanoma]
Neoplasm Metastasis
[The relation between integrin, type IV collagenase and extracellular matrix in invasion and metastasis of gastric carcinoma]
Neoplasm Metastasis
[The Role and Mechanism of CXCR4 and Its Ligand SDF-1 in the Development of Cervical Cancer Metastasis.]
Neoplasm Metastasis
[The role of CXCR4 in lung cancer metastasis and its possible mechanism]
Neoplasm Metastasis
[The role of MMP-2 in the invasion and metastasis of hepatocellular carcinoma (HCC)]
Neoplasm Metastasis
[The serum concentration of metalloproteinase 9 and 2 in non-small cell lung cancer patients]
Neoplasm Metastasis
[Type IV collagenase activities in human colorectal cancers and its role in cancer invasion and metastasis]
Neoplasm Metastasis
[Type IV collagenase activities in human colorectal carcinomas and its role in hepatic metastasis: preliminary report]
Neoplasm Metastasis
[Type IV collagenase expression in human prostate carcinoma cell lines with different metastasis potentials]
Neoplasm Micrometastasis
A third-generation matrix metalloproteinase (MMP) inhibitor (ONO-4817) combined with docetaxel suppresses progression of lung micrometastasis of MMP-expressing tumor cells in nude mice.
Neoplasm Micrometastasis
Differential expression of matrix metalloproteinase-2 expression in disseminated tumor cells and micrometastasis in bone marrow of patients with nonmetastatic and metastatic prostate cancer: theoretical considerations and clinical implications-an immunocytochemical study.
Neoplasm Micrometastasis
Effect of androgen blockade on HER-2 and matrix metalloproteinase-2 expression on bone marrow micrometastasis and stromal cells in men with prostate cancer.
Neoplasm Micrometastasis
Lymph node micrometastasis and its correlation with MMP-2 expression in gastric carcinoma.
Neoplasm Micrometastasis
[Detection of micrometastases in sentinel lymph nodes of breast cancer]
Neoplasm, Residual
Radiation enhances long-term metastasis potential of residual hepatocellular carcinoma in nude mice through TMPRSS4-induced epithelial-mesenchymal transition.
Neoplasm, Residual
The expression and activity of MMPs are increased in residual tumor tissues after the termination of immunotherapy.
Neoplasm, Residual
The expression and clinical significance of metastasis suppressor gene and matrix metalloproteinase-2 in esophageal squamous cell of carcinoma.
Neoplasms
'Increased expression of seprase, a membrane-type serine protease, is associated with lymph node metastasis in human colorectal cancer'.
Neoplasms
(-)-Epigallocatechin gallate inhibits membrane-type 1 matrix metalloproteinase, MT1-MMP, and tumor angiogenesis.
Neoplasms
(-)-Kusunokinin inhibits breast cancer in N-nitrosomethylurea-induced mammary tumor rats.
Neoplasms
(-)-Oleocanthal inhibits growth and metastasis by blocking activation of STAT3 in human hepatocellular carcinoma.
Neoplasms
(2-Aminobenzothiazole)-Methyl-1,1-Bisphosphonic Acids: Targeting Matrix Metalloproteinase 13 Inhibition to the Bone.
Neoplasms
1-furan-2-yl-3-pyridin-2-yl-propenone inhibits the invasion and migration of HT1080 human fibrosarcoma cells through the inhibition of proMMP-2 activation and down regulation of MMP-9 and MT1-MMP.
Neoplasms
1-Trifluoromethoxyphenyl-3-(1-Propionylpiperidin-4-yl) Urea Protects the Blood-Brain Barrier Against Ischemic Injury by Upregulating Tight Junction Protein Expression, Mitigating Apoptosis and Inflammation InVivo and In Vitro Model.
Neoplasms
1Genes responsive to both oxidant stress and loss of estrogen receptor function identify a poor prognosis group of estrogen receptor positive primary breast cancers.
Neoplasms
2-Dodecyl-6-methoxycyclohexa-2,5-diene-1,4-dione inhibits the growth and metastasis of breast carcinoma in mice.
Neoplasms
3,5-Dicaffeoyl-epi-quinic acid inhibits the PMA-stimulated activation and expression of MMP-9 but not MMP-2 via downregulation of MAPK pathway.
Neoplasms
4-HPR impairs bladder cancer cell migration and invasion by interfering with the Wnt5a/JNK and Wnt5a/MMP-2 signaling pathways.
Neoplasms
72-kilodalton type IV collagenase, type IV collagen, and Ki 67 antigen in serous tumors or the ovary: a clinicopathologic, immunohistochemical, and Serological study.
Neoplasms
92-kd gelatinase is actively expressed by eosinophils and stored by neutrophils in squamous cell carcinoma.
Neoplasms
?-Solanine inhibits human melanoma cell migration and invasion by reducing matrix metalloproteinase-2/9 activities.
Neoplasms
?3GnT8 plays an important role in CD147 signal transduction as an upstream modulator of MMP production in tumor cells.
Neoplasms
?3GnT8 Regulates Laryngeal Carcinoma Cell Proliferation Via Targeting MMPs/TIMPs and TGF-?1.
Neoplasms
A 170-kDa membrane-bound protease is associated with the expression of invasiveness by human malignant melanoma cells.
Neoplasms
A case for the use of receiver operating characteristic analysis of potential clinical efficacy biomarkers in advanced renal cell carcinoma.
Neoplasms
A chimera of a gelatinase inhibitor peptide with streptavidin as a bifunctional tumor targeting reagent.
Neoplasms
A chimera of green fluorescent protein with gelatinase binding and tumor targeting peptide.
Neoplasms
A Co-Culture System of Three-Dimensional Tumor-Associated Macrophages and Three-Dimensional Cancer-Associated Fibroblasts Combined with Biomolecule Release for Cancer Cell Migration.
Neoplasms
A Combined Approach Employing Chlorotoxin-Nanovectors and Low Dose Radiation To Reach Infiltrating Tumor Niches in Glioblastoma.
Neoplasms
A comparative study of MMP-1, MMP-2, and TNF-? expression in different acne vulgaris lesions.
Neoplasms
A comparison of ocular melanocyte and uveal melanoma cell invasion and the implication of alpha1beta1, alpha4beta1 and alpha6beta1 integrins.
Neoplasms
A comparison of the biological features between prostate cancers arising in the transition and peripheral zones.
Neoplasms
A comprehensive review on controls in molecular imaging: lessons from MMP-2 imaging.
Neoplasms
A conjugate of camptothecin and a somatostatin analog against prostate cancer cell invasion via a possible signaling pathway involving PI3K/Akt, alphaVbeta3/alphaVbeta5 and MMP-2/-9.
Neoplasms
A coumarin-based fluorescence resonance energy transfer probe targeting matrix metalloproteinase-2 for the detection of cervical cancer.
Neoplasms
A dual-functional magnetic microsphere for ICP-MS quantification and fluorescence imaging of matrix metalloproteinase 2 in cell secretion.
Neoplasms
A Fluorescent Gelatin Degradation Assay to Study Melanoma Breakdown of Extracellular Matrix.
Neoplasms
A functional polymorphism in the matrix metalloproteinase-2 gene promoter (-1306C/T) is associated with risk of development but not metastasis of gastric cardia adenocarcinoma.
Neoplasms
A gelatin in situ-overlay technique localizes brain matrix metalloproteinase activity in experimental focal cerebral ischemia.
Neoplasms
A high serum matrix metalloproteinase-2 level is associated with an adverse prognosis in node-positive breast carcinoma.
Neoplasms
A High-Cholesterol Diet Increases Toll-like Receptors and Other Harmful Factors in the Rabbit Myocardium: The Beneficial Effect of Statins.
Neoplasms
A key role of microRNA-29b for the suppression of colon cancer cell migration by American ginseng.
Neoplasms
A matrix metalloproteinase 2 cleavable melittin/avidin conjugate specifically targets tumor cells in vitro and in vivo.
Neoplasms
A Mercaptoacetamide-Based Class II Histone Deacetylase Inhibitor Suppresses Cell Migration and Invasion in Monomorphic Malignant Human Glioma Cells by Inhibiting FAK/STAT3 Signaling.
Neoplasms
A Multi-functional Vector for delivery of Genome Editing Plasmid Targeting ?-Catenin to Re-modulate Cancer Cell Properties.
Neoplasms
A multicentre cohort study of serum and peritoneal biomarkers to predict anastomotic leakage after rectal cancer resection.
Neoplasms
A multiplicity of anti-invasive effects of farnesyl transferase inhibitor SCH66336 in human head and neck cancer.
Neoplasms
A New Histone Deacetylase Inhibitor, MHY219, Inhibits the Migration of Human Prostate Cancer Cells via HDAC1.
Neoplasms
A Novel MMP-2 Inhibitor 3-azidowithaferin A (3-azidoWA) Abrogates Cancer Cell Invasion and Angiogenesis by Modulating Extracellular Par-4.
Neoplasms
A novel strategy for designing specific gelatinase A inhibitors: potential use to control tumor progression.
Neoplasms
A Novel Synthetic Compound (E)-5-((4-oxo-4H-chromen-3-yl)methyleneamino)-1-phenyl-1H-pyrazole-4-carbonitrile Inhibits TNF?-Induced MMP9 Expression via EGR-1 Downregulation in MDA-MB-231 Human Breast Cancer Cells.
Neoplasms
A novel tripeptide, tyroserleutide, inhibits irradiation-induced invasiveness and metastasis of hepatocellular carcinoma in nude mice.
Neoplasms
A nutrient mixture inhibits glioblastoma xenograft U-87 MG growth in male nude mice.
Neoplasms
A phase I and pharmacokinetic study of the selective, non-peptidic inhibitor of matrix metalloproteinase BAY 12-9566 in combination with etoposide and carboplatin.
Neoplasms
A plant-based medicinal food inhibits the growth of human gastric carcinoma by reversing epithelial-mesenchymal transition via the canonical Wnt/?-catenin signaling pathway.
Neoplasms
A plasma membrane-associated component of ovarian adenocarcinoma cells enhances the catalytic efficiency of matrix metalloproteinase-2.
Neoplasms
A quantitative evaluation of active gelatinolytic sites in uterine endometrioid adenocarcinoma using film in situ zymography: association of stronger gelatinolysis with myometrial invasion.
Neoplasms
A quicker degradation rate is yielded by a novel kind of transgenic silk fibroin consisting of shortened silk fibroin heavy chains fused with matrix metalloproteinase cleavage sites.
Neoplasms
A role for AP-1 in matrix metalloproteinase production and invadopodia formation of v-Crk-transformed cells.
Neoplasms
A role for endothelial-derived matrix metalloproteinase-2 in breast cancer cell transmigration across the endothelial-basement membrane barrier.
Neoplasms
A short-hairpin RNA targeting osteopontin downregulates MMP-2 and MMP-9 expressions in prostate cancer PC-3 cells.
Neoplasms
A single nucleotide polymorphism in the matrix metalloproteinase 2 promoter is closely associated with high risk of nasopharyngeal carcinoma in Cantonese from southern China.
Neoplasms
A single nucleotide polymorphism in the MMP-9 promoter affects tumor progression and invasive phenotype of gastric cancer.
Neoplasms
A size switchable nanoplatform for targeting the tumor microenvironment and deep tumor penetration.
Neoplasms
A size-shrinkable matrix metallopeptidase-2-sensitive delivery nanosystem improves the penetration of human programmed death-ligand 1 siRNA into lung-tumor spheroids.
Neoplasms
A Smart Photosensitizer-Cerium Oxide Nanoprobe for Highly Selective and Efficient Photodynamic Therapy.
Neoplasms
A Study of Matrix Metalloproteinase-2 and Interleukin-18 in Preinvasive and Invasive Lesions of Cancer Cervix.
Neoplasms
A study on angiogenesis-related matrix metalloproteinase networks in primary hepatocellular carcinoma.
Neoplasms
A synergistic interaction of transcription factors AP2 and YB-1 regulates gelatinase A enhancer-dependent transcription.
Neoplasms
A tumoural angiogenic gateway blocker, Benzophenone-1B represses the HIF-1? nuclear translocation and its target gene activation against neoplastic progression.
Neoplasms
Aberrant expression of clock gene period1 and its correlations with the growth, proliferation and metastasis of buccal squamous cell carcinoma.
Neoplasms
Ablation of EIF5A2 induces tumor vasculature remodeling and improves tumor response to chemotherapy via regulation of matrix metalloproteinase 2 expression.
Neoplasms
Accelerated orthotopic hepatocellular carcinomas growth is linked to increased expression of pro-angiogenic and prometastatic factors in murine liver fibrosis.
Neoplasms
Accumulation of extracellular matrix in the liver induces high metastatic potential of hepatocellular carcinoma to the lung.
Neoplasms
Acidic mucopolysaccharide from Holothuria Leucospilota has antitumor effect by inhibiting angiogenesis and tumor cell invasion in vivo and in vitro.
Neoplasms
ACPI Conjugated Gold Nanorods as Nanoplatform for Dual Image Guided Activatable Photodynamic and Photothermal Combined Therapy In Vivo.
Neoplasms
ACTIBIND, a T2 RNase, competes with angiogenin and inhibits human melanoma growth, angiogenesis, and metastasis.
Neoplasms
Actinidia callosa var. callosa suppresses metastatic potential of human hepatoma cell SK-Hep1 by inhibiting matrix metalloproteinase-2 through PI3K/Akt and MAPK signaling pathways.
Neoplasms
Activatable T1 Relaxivity Recovery Nanoconjugates for Kinetic and Sensitive Analysis of Matrix Metalloprotease 2.
Neoplasms
Activated leukocyte cell adhesion molecule (ALCAM/CD166/MEMD), a novel actor in invasive growth, controls matrix metalloproteinase activity.
Neoplasms
Activated leukocyte cell adhesion molecule is expressed in neuroepithelial neoplasms and decreases with tumor malignancy, matrix metalloproteinase 2 expression, and absence of IDH1R132H mutation.
Neoplasms
Activated matrix metalloproteinase-2--a potential marker of prognosis for epithelial ovarian cancer.
Neoplasms
Activation of AKT signaling promotes epithelial-mesenchymal transition and tumor growth in colorectal cancer cells.
Neoplasms
Activation of fibroblast-derived matrix metalloproteinase-2 by colon-cancer cells in non-contact Co-cultures.
Neoplasms
Activation of human umbilical vein endothelial cell progelatinase A by phorbol myristate acetate: a protein kinase C-dependent mechanism involving a membrane-type matrix metalloproteinase.
Neoplasms
Activation of Large form Galanin-LI by Extracellular Processing in Small Cell Lung Carcinoma Tissue.
Neoplasms
Activation of matrix metalloproteinase (MMP)-2 by membrane type 1-MMP and abnormal immunolocalization of the basement membrane components laminin and type IV collagen in canine spontaneous hemangiosarcomas.
Neoplasms
Activation of matrix metalloproteinase-2 (MMP-2) by membrane type 1 matrix metalloproteinase through an artificial receptor for proMMP-2 generates active MMP-2.
Neoplasms
Activation of matrix metalloproteinase-2 by overexpression of manganese superoxide dismutase in human breast cancer MCF-7 cells involves reactive oxygen species.
Neoplasms
Activation of matrix metalloproteinase-2 in head and neck squamous cell carcinoma: studies of clinical samples and in vitro cell lines co-cultured with fibroblasts.
Neoplasms
Activation of matrix metalloproteinase-2 is correlated with invasiveness in thymic epithelial tumors.
Neoplasms
Activation of MMP-2 by human GCT23 giant cell tumour cells induced by osteopontin, bone sialoprotein and GRGDSP peptides is RGD and cell shape change dependent.
Neoplasms
Activation of progelatinase A (MMP-2) by neutrophil elastase, cathepsin G, and proteinase-3: a role for inflammatory cells in tumor invasion and angiogenesis.
Neoplasms
Activation of Snail and EMT-Like Signaling via the IKK??/NF-?B Pathway in Apicidin-Resistant HA22T Hepatocellular Carcinoma Cells.
Neoplasms
Activation of the precursor of gelatinase A/72 kDa type IV collagenase/MMP-2 in lung carcinomas correlates with the expression of membrane-type matrix metalloproteinase (MT-MMP) and with lymph node metastasis.
Neoplasms
Activation of toll-like receptor-2 by endogenous matrix metalloproteinase-2 modulates dendritic-cell-mediated inflammatory responses.
Neoplasms
Activation of tumor cell matrix metalloproteinase-2 by neutrophil proteinases requires expression of membrane-type 1 matrix metalloproteinase.
Neoplasms
Activation of tumor cell proliferation by thyroid hormone in a mouse model of follicular thyroid carcinoma.
Neoplasms
Activation ratio of MMP-2 and expression of MT1-MMP are correlated in thymic epithelial tumours.
Neoplasms
Activation State of Stromal Inflammatory Cells in Murine Metastatic Pancreatic Adenocarcinoma.
Neoplasms
Activator Protein-2? Promotes Tumor Growth and Predicts Poor Prognosis in Breast Cancer.
Neoplasms
Active and inactive forms of matrix metalloproteinases 2 and 9 in cutaneous melanoma.
Neoplasms
Active immunogene therapy of cancer with vaccine on the basis of chicken homologous matrix metalloproteinase-2.
Neoplasms
Active matrix metalloproteinase-2 activity discriminates colonic mucosa, adenomas with and without high-grade dysplasia, and cancers.
Neoplasms
Activities and polymorphisms of MMP-2 and MMP-9, smoking, diabetes and risk of prostate cancer.
Neoplasms
Activity and cellular origin of gelatinases in patients with colon and rectal carcinoma differential activity of matrix metalloproteinase-9.
Neoplasms
Activity and expression of urokinase-type plasminogen activator and matrix metalloproteinases in human colorectal cancer.
Neoplasms
Activity of type IV collagenases (MMP-2 and MMP-9) in primary pulmonary carcinomas: a quantitative analysis.
Neoplasms
ADAM12 redistributes and activates MMP-14, resulting in gelatin degradation, reduced apoptosis, and increased tumor growth.
Neoplasms
Adapting and Remolding: Orchestrating Tumor Microenvironment Normalization with Photodynamic Therapy by Size Transformable Nanoframeworks.
Neoplasms
Addition of matrix metalloproteinase inhibition to conventional cytotoxic therapy reduces tumor implantation and prolongs survival in a murine model of human pancreatic cancer.
Neoplasms
Adenosine Inhibits Ovarian Cancer Growth Through Regulating RhoGDI2 Protein Expression.
Neoplasms
Adenovirus E1A represses protease gene expression and inhibits metastasis of human tumor cells.
Neoplasms
Adenovirus-mediated ING4 expression suppresses lung carcinoma cell growth via induction of cell cycle alteration and apoptosis and inhibition of tumor invasion and angiogenesis.
Neoplasms
Adenovirus-mediated small interfering RNA against matrix metalloproteinase-2 suppresses tumor growth and lung metastasis in mice.
Neoplasms
Adenovirus-mediated transfer of siRNA against MMP-2 mRNA results in impaired invasion and tumor-induced angiogenesis, induces apoptosis in vitro and inhibits tumor growth in vivo in glioblastoma.
Neoplasms
Aging of stromal-derived human breast fibroblasts might contribute to breast cancer progression.
Neoplasms
Alendronate blocks TGF-beta1 stimulated collagen 1 degradation by human prostate PC-3 ML cells.
Neoplasms
Alendronate inhibits intraperitoneal dissemination in in vivo ovarian cancer model.
Neoplasms
Alendronate regulates cell invasion and MMP-2 secretion in human osteosarcoma cell lines.
Neoplasms
Alkaloid and phenolic compounds of Xylopia aromatica inhibits tumor growth by down-regulating matrix metalloproteinase-2 (MMP-2) expression.
Neoplasms
All-Trans Retinoic Acid Enhances Matrix Metalloproteinase 2 Expression and Secretion in Human Myeloid Leukemia THP-1 Cells.
Neoplasms
alpha v beta3-dependent cross-presentation of matrix metalloproteinase-2 by melanoma cells gives rise to a new tumor antigen.
Neoplasms
alpha-Lipoic acid reduces matrix metalloproteinase activity in MDA-MB-231 human breast cancer cells.
Neoplasms
Alteration of MMP-2 and -14 expression by imatinib in HPV-positive and -negative squamous cell carcinoma.
Neoplasms
Alteration of the Methylation Status of Tumor-Promoting Genes Decreases Prostate Cancer Cell Invasiveness and Tumorigenesis In vitro and In vivo.
Neoplasms
Altered expression of metastasis-associated and regulatory molecules in effusions from breast cancer patients: a novel model for tumor progression.
Neoplasms
Altered transcriptional regulation of human interstitial collagenase in cultured skin fibroblasts from older donors.
Neoplasms
Alternagin-C binding to ?2?1 integrin controls matrix metalloprotease-9 and matrix metalloprotease-2 in breast tumor cells and endothelial cells.
Neoplasms
Alternative pathway for the role of furin in tumor cell invasion process. Enhanced MMP-2 levels through bioactive TGFbeta.
Neoplasms
Aluminum naphthalocyanine conjugate as an MMP-2-activatable photoacoustic probe for in vivo tumor imaging.
Neoplasms
Ameloblastic neoplasia spectrum: a cross-sectional study of MMPS expression and proliferative activity.
Neoplasms
Amentoflavone Inhibits Experimental Tumor Metastasis Through a Regulatory Mechanism Involving MMP-2, MMP-9, Prolyl Hydroxylase, Lysyl Oxidase, VEGF, ERK-1, ERK-2, STAT-1, nm23 and Cytokines in Lung Tissues of C57BL/6 Mice.
Neoplasms
Ampelopsin suppresses TNF-?-induced migration and invasion of U2OS osteosarcoma cells.
Neoplasms
Amplified and label-free electrochemical detection of a protease biomarker by integrating proteolysis-triggered transcription.
Neoplasms
An animal model for colon cancer metastasis: establishment and characterization of murine cell lines with enhanced liver-metastasizing ability.
Neoplasms
An Au-Se nanoprobe for the evaluation of the invasive potential of breast cancer cells via imaging the sequential activation of uPA and MMP-2.
Neoplasms
An endogenous inhibitor of angiogenesis inversely correlates with side population phenotype and function in human lung cancer cells.
Neoplasms
An evaluation of neurocognitive status and markers of immune activation as predictors of time to death in advanced HIV infection.
Neoplasms
An integrated computational and experimental approach to gaining selectivity for MMP-2 within the gelatinase subfamily.
Neoplasms
An inverse relationship between KAI1 expression, invasive ability, and MMP-2 expression and activity in bladder cancer cell lines.
Neoplasms
An MMP-2 Responsive Liposome Integrating Antifibrosis and Chemotherapeutic Drugs for Enhanced Drug Perfusion and Efficacy in Pancreatic Cancer.
Neoplasms
An osteoblast-derived proteinase controls tumor cell survival via TGF-beta activation in the bone microenvironment.
Neoplasms
Analysis of expression of matrix metalloproteinases-2 and -9 in hypopharyngeal squamous cell carcinoma by in situ hybridization.
Neoplasms
Analysis of the capillary architecture in the precursors of prostate cancer: recent findings and new concepts.
Neoplasms
Andrographolide enhances the anti-metastatic effect of radiation in Ras-transformed cells via suppression of ERK-mediated MMP-2 activity.
Neoplasms
Angiogenesis and tumor growth inhibition by a matrix metalloproteinase inhibitor targeting radiation-induced invasion.
Neoplasms
Angiogenesis in renal cell carcinoma: Evaluation of microvessel density, vascular endothelial growth factor and matrix metalloproteinases.
Neoplasms
Angiogenesis in vestibular schwannomas: expression of extracellular matrix factors MMP-2, MMP-9, and TIMP-1.
Neoplasms
Angiogenin contributes to bladder cancer tumorigenesis by DNMT3b-mediated MMP2 activation.
Neoplasms
Angiopep-2 and activatable cell penetrating peptide dual modified nanoparticles for enhanced tumor targeting and penetrating.
Neoplasms
Angiopoietin 2 displays a vascular endothelial growth factor dependent synergistic effect in hepatocellular carcinoma development in mice.
Neoplasms
Angiopoietin 2 induces glioma cell invasion by stimulating matrix metalloprotease 2 expression through the alphavbeta1 integrin and focal adhesion kinase signaling pathway.
Neoplasms
Angiopoietin-2 induces human glioma invasion through the activation of matrix metalloprotease-2.
Neoplasms
Angiotensin II-induced MMP-2 release from endothelial cells is mediated by TNF-alpha.
Neoplasms
Angiotensin receptor blocker Losartan inhibits tumor growth of colorectal cancer.
Neoplasms
Annexin II promotes invasion and migration of human hepatocellular carcinoma cells in vitro via its interaction with HAb18G/CD147.
Neoplasms
Anthocyanins from the Fruit of Vitis Coignetiae Pulliat Inhibit TNF-Augmented Cancer Proliferation, Migration, and Invasion in A549 Cells
Neoplasms
Anti-beta4 integrin antibodies enhance migratory and invasive abilities of human colon adenocarcinoma cells and their MMP-2 expression.
Neoplasms
Anti-cancer effect of metformin on the metastasis and invasion of primary breast cancer cells through mediating NF-kB activity.
Neoplasms
Anti-inflammatory and anti-oxidant properties of Schisandrin C promote mitochondrial biogenesis in human dental pulp cells.
Neoplasms
Anti-invasion and anti-tumor growth effect of doxycycline treatment for human oral squamous-cell carcinoma--in vitro and in vivo studies.
Neoplasms
Anti-metastatic and anti-angiogenic activities of sulfated polysaccharide of Sepiella maindroni ink
Neoplasms
Anti-metastatic and anti-angiogenic activities of sulfated polysaccharide of Sepiella maindroni ink.
Neoplasms
Anti-metastatic effect of deoxyelephantopin from Elephantopus scaber in A549 lung cancer cells in vitro.
Neoplasms
Anti-Metastatic Effects of Antrodan with and without Cisplatin on Lewis Lung Carcinomas in a Mouse Xenograft Model.
Neoplasms
Anti-metastatic effects of isolinderalactone via the inhibition of MMP-2 and up regulation of NM23-H1 expression in human lung cancer A549 cells.
Neoplasms
Anti-proliferative and anti-invasive effects of garcinol from Garcinia indica on gallbladder carcinoma cells.
Neoplasms
Anti-proliferative effects of mesenchymal stem cells (MSCs) derived from multiple sources on ovarian cancer cell lines: an in-vitro experimental study.
Neoplasms
Anti-tubulin agent vinorelbine inhibits metastasis of cancer cells by regulating epithelial-mesenchymal transition.
Neoplasms
Antiangiogenic activity of selenium in cancer chemoprevention: metabolite-specific effects.
Neoplasms
Anticancer activities of an anthocyanin-rich extract from black rice against breast cancer cells in vitro and in vivo.
Neoplasms
Anticancer effect of lysine, proline, arginine, ascorbic acid and green tea extract on human renal adenocarcinoma line 786-0.
Neoplasms
Antimetastatic effects of gambogic acid are mediated via the actin cytoskeleton and NF-?B pathways in SK-HEP1 cells.
Neoplasms
Antimetastatic Potentials of Phyllanthusurinaria L on A549 and Lewis Lung Carcinoma Cells via Repression of Matrix-Degrading Proteases.
Neoplasms
Antineoplastic effect of intracellular expression of a single-chain antibody directed against type IV collagenase.
Neoplasms
Antisense Deoxyoligonucleotides Inhibit Activities of Matrix Metalloproteinase-2 in Human Fibrosarcoma HT1080 Cells.
Neoplasms
Antitumor activity of anti-type IV collagenase monoclonal antibody and its lidamycin conjugate against colon carcinoma.
Neoplasms
Antitumor activity of triptolide in SKOV3 cells and SKOV3/DDP in vivo and in vitro.
Neoplasms
Antitumor and antimetastatic actions of dihydroxycoumarins (esculetin or fraxetin) through the inhibition of M2 macrophage differentiation in tumor-associated macrophages and/or G1 arrest in tumor cells.
Neoplasms
Antitumor and radiosensitizing synergistic effects of apigenin and cryptotanshinone against solid Ehrlich carcinoma in female mice.
Neoplasms
Antitumor effects of aconitine in A2780 cells via estrogen receptor ??mediated apoptosis, DNA damage and migration.
Neoplasms
Antitumor effects of dioscin in A431 cells via adjusting ATM/p53-mediated cell apoptosis, DNA damage and migration.
Neoplasms
Antitumor effects of recombinant human adenovirus-p53 against human cutaneous squamous cell carcinoma in mice.
Neoplasms
Antitumor effects of the molecule-downsized immunoconjugate composed of lidamycin and Fab' fragment of monoclonal antibody directed against type IV collagenase.
Neoplasms
Antitumor evaluation of carboxymethyl chitosan based norcantharidin conjugates against gastric cancer as novel polymer therapeutics.
Neoplasms
Antitumor progression potential of morusin suppressing STAT3 and NF?B in human hepatoma SK-Hep1 cells.
Neoplasms
Antiulcer activity of anthocyanins from Rubus coreanus via association with regulation of the activity of matrix metalloproteinase-2.
Neoplasms
Apigenin Attenuates Insulin-Like Growth Factor-I Signaling in an Autochthonous Mouse Prostate Cancer Model.
Neoplasms
Areca nut alkaloids induce irreparable DNA damage and senescence in fibroblasts and may create a favourable environment for tumour progression.
Neoplasms
Arginase 1 is expressed in myelocytes/metamyelocytes and localized in gelatinase granules of human neutrophils.
Neoplasms
ARP101, a selective MMP-2 inhibitor, induces autophagy-associated cell death in cancer cells.
Neoplasms
Arsenic trioxide (As(2)O(3)) inhibits peritoneal invasion of ovarian carcinoma cells in vitro and in vivo.
Neoplasms
Arsenic trioxide (As2O3) reduces the invasive and metastatic properties of cervical cancer cells in vitro and in vivo.
Neoplasms
Arylamino methylene bisphosphonate derivatives as bone seeking matrix metalloproteinase inhibitors.
Neoplasms
Aspirin inhibits matrix metalloproteinase-2 activity, increases E-cadherin production, and inhibits in vitro invasion of tumor cells.
Neoplasms
ASSESSMENT OF GELATINASE AND TUMOR NECROSIS FACTOR-? LEVEL IN THE VITREOUS AND SERUM OF PATIENTS WITH EALES DISEASE: Role of Inflammation-Mediated Angiogenesis in the Pathogenesis of Eales Disease.
Neoplasms
Assessment of indirect hemagglutination and zymography procedures in evaluation of gelatinase a in patients with benign and malignant prostate hyperplasia.
Neoplasms
Assessment of MicroRNA (miR)-365 Effects on Oral Squamous Carcinoma Cell Line Phenotypes.
Neoplasms
Assessment of the clinical significance of serum matrix metalloproteinases MMP-2 and MMP-9 in patients with various chronic liver diseases and hepatocellular carcinoma.
Neoplasms
Assessment of the Inhibitory Effects of Ficin-hydrolyzed Gelatin Derived from Squid (Uroteuthis duvauceli) on Breast Cancer Cell Lines and Animal Model.
Neoplasms
Assessment of the involvement of the macrophage migration inhibitory factor-glucocorticoid regulatory dyad in the expression of matrix metalloproteinase-2 during periodontitis.
Neoplasms
Association between cyclooxygenase-2 and matrix metalloproteinase-2 expression in non-small cell lung cancer.
Neoplasms
Association between expression of activated 72-kilodalton gelatinase and tumor spread in non-small-cell lung carcinoma.
Neoplasms
Association between ratio of matrix metalloproteinase-1 to tissue inhibitor of metalloproteinase-1 and local recurrence, metastasis, and survival in human chondrosarcoma.
Neoplasms
Association of cavernous malformation within vestibular schwannoma: immunohistochemical analysis of matrix metalloproteinase-2 and -9.
Neoplasms
Association of cyclooxygenase-2 and matrix metalloproteinase-2 expression in human breast cancer.
Neoplasms
Association of E-cadherin, matrix metalloproteinases, and tissue inhibitors of metalloproteinases with the progression and metastasis of hepatocellular carcinoma.
Neoplasms
Association of fibrotic remodeling and cytokines/chemokines content in epicardial adipose tissue with atrial myocardial fibrosis in patients with atrial fibrillation.
Neoplasms
Association of increased phosphatidylinositol 3-kinase signaling with increased invasiveness and gelatinase activity in malignant gliomas.
Neoplasms
Association of matrix metalloproteinase (MMP)-2 and -9 expression with extra-gastrointestinal stromal tumor metastasis.
Neoplasms
Association of matrix metalloproteinase-2 and -9 promoter polymorphisms with colorectal cancer in Chinese.
Neoplasms
Association of MMP-2 activation potential with metastatic progression in human breast cancer cell lines independent of MMP-2 production.
Neoplasms
Association of single nucleotide polymorphisms of ?2-adrenergic receptor gene with clinicopathological features of pancreatic carcinoma.
Neoplasms
Association of suppression of extracellular signal-regulated kinase phosphorylation by epigallocatechin gallate with the reduction of matrix metalloproteinase activities in human fibrosarcoma HT1080 cells.
Neoplasms
Association of type II apoptosis and 92-kDa type IV collagenase expression in human amniochorion in prematurely ruptured membranes with tumor necrosis factor receptor-1 expression.
Neoplasms
Associations between single nucleotide polymorphisms of COX-2 and MMP-2 genes and colorectal cancer susceptibility in the Saudi population.
Neoplasms
Asymmetric dimethylarginine as a useful risk marker of radial artery calcification in patients with advanced kidney disease.
Neoplasms
Ataxia telangiectasia-mutated gene is a possible biomarker for discrimination of infiltrative deep penetrating nevi and metastatic vertical growth phase melanoma.
Neoplasms
Attenuated expression and function of the RECK tumor suppressor under hypoxic conditions is mediated by the MAPK signaling pathways.
Neoplasms
Attenuated liver tumor formation in the absence of CCR2 with a concomitant reduction in the accumulation of hepatic stellate cells, macrophages and neovascularization.
Neoplasms
Attenuation of chloroquine and hydroxychloroquine on the invasive potential of bladder cancer through targeting matrix metalloproteinase 2 expression.
Neoplasms
Attenuation of melanoma invasion by a secreted variant of activated leukocyte cell adhesion molecule.
Neoplasms
Attenuation of methylglyoxal-induced peritoneal fibrosis: immunomodulation by interleukin-10.
Neoplasms
Au-Se-Bond-Based Nanoprobe for Imaging MMP-2 in Tumor Cells under a High-Thiol Environment.
Neoplasms
Au-siRNA@ aptamer nanocages as a high-efficiency drug and gene delivery system for targeted lung cancer therapy.
Neoplasms
Aurora-A modulates MMP-2 expression via AKT/NF-?B pathway in esophageal squamous cell carcinoma cells.
Neoplasms
Autocrine factor enhancing the secretion of M(r) 95,000 gelatinase (matrix metalloproteinase 9) in serum-free medium conditioned with murine metastatic colon carcinoma cells.
Neoplasms
Autocrine factors, type IV collagenase secretion and prostatic cancer cell invasion.
Neoplasms
Autocrine induction of tumor protease production and invasion by a metallothionein-regulated TGF-beta 1 (Ser223, 225).
Neoplasms
Azelnidipine suppresses the progression of aortic aneurysm in wild mice model through anti-inflammatory effects.
Neoplasms
Bacoside A downregulates matrix metalloproteinases 2 and 9 in DEN-induced hepatocellular carcinoma.
Neoplasms
Baicalein inhibits inflammatory response and promotes osteogenic activity in periodontal ligament cells challenged with lipopolysaccharides.
Neoplasms
Baicalein inhibits pulmonary carcinogenesis-associated inflammation and interferes with COX-2, MMP-2 and MMP-9 expressions in-vivo.
Neoplasms
Balance between activation and inhibition of matrix metalloproteinase-2 (MMP-2) is altered in colorectal tumors compared to normal colonic epithelium.
Neoplasms
Barnidipine compared to lercanidipine in addition to losartan on endothelial damage and oxidative stress parameters in patients with hypertension and type 2 diabetes mellitus.
Neoplasms
Basement membrane and the SIKVAV laminin-derived peptide promote tumor growth and metastases.
Neoplasms
Basement membrane patterns, gelatinase A and tissue inhibitor of metalloproteinase-2 expressions, and stromal fibrosis during the development of peripheral lung adenocarcinoma.
Neoplasms
Bcl-2 overexpression in melanoma cells increases tumor progression-associated properties and in vivo tumor growth.
Neoplasms
Bcl-2 promotes invasion and lung metastasis by inducing matrix metalloproteinase-2.
Neoplasms
BCRP expression in VX2 rabbit liver tumours and its effects on tumour recurrence, metastasis and treatment tolerability.
Neoplasms
Behavior of murine renal carcinoma cells grown in ectopic or orthotopic sites in syngeneic mice.
Neoplasms
Beneficial paracrine effects of cannabinoid receptor 2 on liver injury and regeneration.
Neoplasms
Benzyl isothiocyanate suppresses pancreatic tumor angiogenesis and invasion by inhibiting HIF-?/VEGF/Rho-GTPases: pivotal role of STAT-3.
Neoplasms
Berberine enhances inhibition of glioma tumor cell migration and invasiveness mediated by arsenic trioxide.
Neoplasms
Berberine suppresses in vitro migration and invasion of human SCC-4 tongue squamous cancer cells through the inhibitions of FAK, IKK, NF-kappaB, u-PA and MMP-2 and -9.
Neoplasms
Beta-endorphin ameliorates synovial cell hyperfunction in the collagen-induced arthritis rat model by specific downregulation of NF-kappa B activity.
Neoplasms
Betulin, betulinic acid and butein are inhibitors of acetaldehyde-induced activation of liver stellate cells.
Neoplasms
Binding affinities for sulfonamide inhibitors with matrix metalloproteinase-2 using a linear response method.
Neoplasms
Binding of alpha2 monoclonal antibody to human cervical tumor cell (SiHa) surface alpha2beta1 integrin modulates MMP-2 activity.
Neoplasms
Binding of alpha5 monoclonal antibody to cell surface alpha5beta1 integrin modulates MMP-2 and MMP-7 activity in B16F10 melanoma cells.
Neoplasms
Binding of novel peptide inhibitors of type IV collagenases to phospholipid membranes and use in liposome targeting to tumor cells in vitro.
Neoplasms
Biobehavioral influences on matrix metalloproteinase expression in ovarian carcinoma.
Neoplasms
Bioengineered Human Serum Albumin Fusion Protein as Target/Enzyme/pH Three-Stage Propulsive Drug Vehicle for Tumor Therapy.
Neoplasms
Biological and clinical significance of MMP-2, MMP-9, TIMP-1 and TIMP-2 in non-small cell lung cancer.
Neoplasms
Biomarkers of anticancer activity of R115777 (Tipifarnib, Zarnestra) in human breast cancer models in vitro.
Neoplasms
Biphenyl substituted lysine derivatives as recognition elements for the matrix metalloproteinases MMP-2 and MMP-9.
Neoplasms
Bit1 knockdown contributes to growth suppression as well as the decreases of migration and invasion abilities in esophageal squamous cell carcinoma via suppressing FAK-paxillin pathway.
Neoplasms
Black tea polyphenol (theaflavin) downregulates MMP-2 in human melanoma cell line A375 by involving multiple regulatory molecules.
Neoplasms
Blockade of endogenous tissue kallikrein aggravates renal injury by enhancing oxidative stress and inhibiting matrix degradation.
Neoplasms
Blockade of Rho/Rho-associated coiled coil-forming kinase signaling can prevent progression of hepatocellular carcinoma in matrix metalloproteinase-dependent manner.
Neoplasms
Blockade of vascular angiogenesis by Aspergillus usamii var. shirousamii-transformed Angelicae Gigantis Radix and Zizyphus jujuba.
Neoplasms
Blockage of Squamous Cancer Cell Collective Invasion by FAK Inhibition Is Released by CAFs and MMP-2.
Neoplasms
Bmal1 suppresses cancer cell invasion by blocking the phosphoinositide 3-kinase-Akt-MMP-2 signaling pathway.
Neoplasms
Bone marrow angiogenesis and plasma cell angiogenic and invasive potential in patients with active multiple myeloma.
Neoplasms
Bone marrow-derived mesenchymal stem cell transplantation attenuates overexpression of inflammatory mediators in rat brain after cardiopulmonary resuscitation.
Neoplasms
Bone sialoprotein binding to matrix metalloproteinase-2 alters enzyme inhibition kinetics.
Neoplasms
Bone sialoprotein does not interact with pro-gelatinase A (MMP-2) or mediate MMP-2 activation.
Neoplasms
Bone sialoprotein, matrix metalloproteinase 2, and alpha(v)beta3 integrin in osteotropic cancer cell invasion.
Neoplasms
Both osteopontin-c and osteopontin-b splicing isoforms exert pro-tumorigenic roles in prostate cancer cells.
Neoplasms
BP-1T, an antiangiogenic benzophenone-thiazole pharmacophore, counteracts HIF-1 signalling through p53/MDM2-mediated HIF-1? proteasomal degradation.
Neoplasms
Breast cancer cells and bone marrow mesenchymal stromal cells: a regulated modulation of the breast tumor in the context of immune response.
Neoplasms
Breast tumor cells transendothelial migration induces endothelial cell anoikis through extracellular matrix degradation.
Neoplasms
Brg-1 is required for maximal transcription of the human matrix metalloproteinase-2 gene.
Neoplasms
Bruton's Tyrosine Kinase (BTK) Inhibitor (Ibrutinib)?-Suppressed Migration and Invasion of Prostate Cancer.
Neoplasms
BubR1 Acts as a Promoter in Cellular Motility of Human Oral Squamous Cancer Cells through Regulating MMP-2 and MMP-9.
Neoplasms
Bufalin inhibits migration and invasion in human hepatocellular carcinoma SK-Hep1 cells through the inhibitions of NF-kB and matrix metalloproteinase-2/-9-signaling pathways.
Neoplasms
c-jun cooperates with SV40 T-antigen to sustain MMP-2 expression in immortalized cells.
Neoplasms
Cadherin-11 involves in synovitis and increases the migratory and invasive capacity of fibroblast-like synoviocytes of osteoarthritis.
Neoplasms
Caffeoyl pyrrolidine derivative LY52 inhibits tumor invasion and metastasis via suppression of matrix metalloproteinase activity.
Neoplasms
CAGE, a cancer/testis antigen, induces c-FLIP(L) and Snail to enhance cell motility and increase resistance to an anti-cancer drug.
Neoplasms
CAGE, a cancer/testis antigen, induces c-FLIPL and Snail to enhance cell motility and increase resistance to an anti-cancer drug
Neoplasms
Calcium regulation of matrix metalloproteinase-mediated migration in oral squamous cell carcinoma cells.
Neoplasms
Cambodian Phellinus linteus inhibits experimental metastasis of melanoma cells in mice via regulation of urokinase type plasminogen activator.
Neoplasms
Cancer cell-associated fibronectin induces release of matrix metalloproteinase-2 from normal fibroblasts.
Neoplasms
Cancer-Specific Survival Stratification Derived from Tumor Expression of Tissue Inhibitor of Metalloproteinase-2 in Non-Metastatic Renal Cell Carcinoma.
Neoplasms
Cancer/Testis Antigens: Expression, Regulation, Tumor Invasion, and Use in Immunotherapy of Cancers.
Neoplasms
Canine Dilated Cardiomyopathy: Diffuse Remodeling, Focal Lesions, and the Involvement of Macrophages and New Vessel Formation.
Neoplasms
Cannabinoids inhibit glioma cell invasion by down-regulating matrix metalloproteinase-2 expression.
Neoplasms
CAPN 7 promotes the migration and invasion of human endometrial stromal cell by regulating matrix metalloproteinase 2 activity.
Neoplasms
Captopril inhibits Matrix Metalloproteinase-2 and extends survival as a temozolomide adjuvant in an intracranial gliosarcoma model.
Neoplasms
Carbamoylphosphonate matrix metalloproteinase inhibitors 3: in vivo evaluation of cyclopentylcarbamoylphosphonic acid in experimental metastasis and angiogenesis.
Neoplasms
Carbamoylphosphonates Control Tumor Cell Proliferation and Dissemination by Simultaneously Inhibiting Carbonic Anhydrase IX and Matrix Metalloproteinase-2. Toward Nontoxic Chemotherapy Targeting Tumor Microenvironment (1).
Neoplasms
Carcinoembryonic antigen and matrix metalloproteinase 2 serum and peritoneal washes concentration in staging and prognosis in colorectal cancer patients.
Neoplasms
Cardiac Dysfunction in Association with Increased Inflammatory Markers in Primary Aldosteronism.
Neoplasms
Carvedilol, a pharmacological antioxidant, inhibits neointimal matrix metalloproteinase-2 and -9 in experimental atherosclerosis.
Neoplasms
Case of primary malignant hemangiopericytoma of the heart expressing basement membrane-degradable enzymes.
Neoplasms
Catalyser-21(TM), a mineral water derived from leaf soil, inhibits tumor cell invasion and angiogenesis.
Neoplasms
Cathepsin G and alpha 1-antichymotrypsin in the local host reaction to loosening of total hip prostheses.
Neoplasms
CCR7 Mediates TGF-?1-Induced Human Malignant Glioma Invasion, Migration, and Epithelial-Mesenchymal Transition by Activating MMP2/9 Through the Nuclear Factor KappaB Signaling Pathway.
Neoplasms
CD133+ cancer stem-like cells promote migration and invasion of salivary adenoid cystic carcinoma by inducing vasculogenic mimicry formation.
Neoplasms
CD147 and matrix metalloproteinase-2 protein expression as significant prognostic factors in esophageal squamous cell carcinoma.
Neoplasms
CD147 and matrix-metalloproteinase-2 expression in metastatic and non-metastatic uveal melanomas.
Neoplasms
CD147, MMP-2, MMP-9 and MVD-CD34 are Significant Predictors of Recurrence After Liver Transplantation in Hepatocellular Carcinoma Patients.
Neoplasms
CD39 is incorporated into plasma microparticles where it maintains functional properties and impacts endothelial activation.
Neoplasms
CD44(+) gastric cancer cells with stemness properties are chemoradioresistant and highly invasive.
Neoplasms
CD73 complexes with emmprin to regulate MMP-2 production from co-cultured sarcoma cells and fibroblasts.
Neoplasms
Celastrol inhibit the proliferation, invasion and migration of human cervical HeLa cancer cells through down-regulation of MMP-2 and MMP-9.
Neoplasms
Celecoxib inhibits cell growth and modulates the expression of matrix metalloproteinases in human osteosarcoma MG-63 cell line.
Neoplasms
Celecoxib inhibits tumor growth and angiogenesis in an orthotopic implantation tumor model of human colon cancer.
Neoplasms
Cell membrane-associated MT1-MMP dependent activation of MMP-2 in SiHa (human cervical cancer) cells.
Neoplasms
Cell membrane-associated MT1-MMP-dependent activation of pro-MMP-2 in A375 melanoma cells.
Neoplasms
Cell surface associated alpha-L: -fucose moieties modulate human breast cancer neoplastic progression.
Neoplasms
Cell surface binding and activation of gelatinase A induced by expression of membrane-type-1-matrix metalloproteinase (MT1-MMP).
Neoplasms
Cell type specific interleukin-6 induced responses in tumor keratinocytes and stromal fibroblasts are essential for invasive growth.
Neoplasms
Cell-based identification of natural substrates and cleavage sites for extracellular proteases by SILAC proteomics.
Neoplasms
Cell-matrix interactions modulate 92-kD gelatinase expression by human bronchial epithelial cells.
Neoplasms
Cell-Permeable, MMP-2 Activatable, Nickel Ferrite and His-Tagged Fusion Protein Self-Assembled Fluorescent Nanoprobe for Tumor Magnetic-Targeting and Imaging.
Neoplasms
Cell-surface-associated tissue transglutaminase is a target of MMP-2 proteolysis.
Neoplasms
Cellular localization of EMMPRIN predicts prognosis of patients with operable lung adenocarcinoma independent from MMP-2 and MMP-9.
Neoplasms
Cellular protein and mRNA expression patterns of matrix metalloproteinases-2, -3 and -9 in human breast cancer: correlation with tumour growth.
Neoplasms
Ceramide inhibition of MMP-2 expression and human cancer bronchial cell invasiveness involve decreased histone acetylation.
Neoplasms
Cerebrospinal fluid levels of MMP-2, 7, and 9 are elevated in association with human immunodeficiency virus dementia.
Neoplasms
Changes in extracellular matrix in different stages of colorectal cancer and their effects on proliferation of cancer cells.
Neoplasms
Changes in MMP-2, MMP-9, inflammation, blood coagulation and intestinal mucosal permeability in patients with active ulcerative colitis.
Neoplasms
Changes of histology and expression of MMP-2 and nm23-H1 in primary and metastatic gastric cancer.
Neoplasms
Changes to N-linked oligosaccharide chains of human serum immunoglobulin G and matrix metalloproteinase-2 with cancer progression.
Neoplasms
Characterization of a von Hippel Lindau pathway involved in extracellular matrix remodeling, cell invasion, and angiogenesis.
Neoplasms
Characterization of extracellular matrix-degrading proteinase and its inhibitor in gynecologic cancer tissues with clinically different metastatic form.
Neoplasms
Characterization of gelatinase from pig polymorphonuclear leucocytes. A metalloproteinase resembling tumour type IV collagenase.
Neoplasms
Characterization of microRNA-29 family expression and investigation of their mechanistic roles in gastric cancer.
Neoplasms
Characterization of phosphoglycerate kinase-1 expression of stromal cells derived from tumor microenvironment in prostate cancer progression.
Neoplasms
Characterization of Spontaneous and TGF-?-Induced Cell Motility of Primary Human Normal and Neoplastic Mammary Cells In Vitro Using Novel Real-Time Technology.
Neoplasms
Chelerythrine suppresses proliferation and metastasis of human prostate cancer cells via modulating MMP/TIMP/NF-?B system.
Neoplasms
Chemical Composition of Pterospermum heterophyllum Root and its Anti-Arthritis Effect on Adjuvant-Induced Arthritis in Rats via Modulation of Inflammatory Responses.
Neoplasms
Chemical design of a radiolabeled gelatinase inhibitor peptide for the imaging of gelatinase activity in tumors.
Neoplasms
Chemically modified tetracyclines (CMT-3 and CMT-8) enable control of the pathologic remodellation of human aortic valve stenosis via MMP-9 and VEGF inhibition.
Neoplasms
Chemo-Photothermal Combination Cancer Therapy with ROS Scavenging, Extracellular Matrix Depletion, and Tumor Immune Activation by Telmisartan and Diselenide-Paclitaxel Prodrug Loaded Nanoparticles.
Neoplasms
Chemokine CXCL12 and its receptor CXCR4 expression are associated with perineural invasion of prostate cancer.
Neoplasms
Chlorogenic Acid Decreases Malignant Characteristics of Hepatocellular Carcinoma Cells by Inhibiting DNMT1 Expression.
Neoplasms
Chlorotoxin-Conjugated Multifunctional Dendrimers Labeled with Radionuclide 131I for Single Photon Emission Computed Tomography Imaging and Radiotherapy of Gliomas.
Neoplasms
Chromodomain Helicase/ATPase DNA-Binding Protein 1-Like Gene (CHD1L) Expression and Implications for Invasion and Metastasis of Breast Cancer.
Neoplasms
Chromosomal, epigenetic and microRNA-mediated inactivation of LRP1B, a modulator of the extracellular environment of thyroid cancer cells.
Neoplasms
Chronic Exposure of Renal Stem Cells to Inorganic Arsenic Induces a Cancer Phenotype.
Neoplasms
Chronic exposure to microcystin-LR increases the risk of prostate cancer and induces malignant transformation of human prostate epithelial cells.
Neoplasms
Chronic inorganic arsenic exposure in vitro induces a cancer cell phenotype in human peripheral lung epithelial cells.
Neoplasms
Chronic liver injury promotes hepatocarcinoma cell seeding and growth, associated with infiltration by macrophages.
Neoplasms
Chronic stress promotes gastric cancer progression and metastasis: an essential role for ADRB2.
Neoplasms
Chronic stress promotes oral cancer growth and angiogenesis with increased circulating catecholamine and glucocorticoid levels in a mouse model.
Neoplasms
Chrysanthemum indicum ethanolic extract inhibits invasion of hepatocellular carcinoma via regulation of MMP/TIMP balance as therapeutic target.
Neoplasms
Cinnamamide, an antitumor agent with low cytotoxicity acting on matrix metalloproteinase.
Neoplasms
CIP4 promotes lung adenocarcinoma metastasis and is associated with poor prognosis.
Neoplasms
Circulating gelatinases are not prognostic of treatment response and survival in locally advanced rectal cancer patients undergoing preoperative chemoradiotherapy.
Neoplasms
Circulating tumor cells and serum levels of MMP-2, MMP-9 and VEGF as markers of the metastatic process in patients with high risk of metastatic progression.
Neoplasms
Circulating tumor cells from a 4-dimensional lung cancer model are resistant to cisplatin.
Neoplasms
Cisplatin and 4-hexylresorcinol synergise to decrease metastasis and increase survival rate in an oral mucosal melanoma xenograft model: a preliminary study.
Neoplasms
Claudin-4 expression is associated with tumor invasion, MMP-2 and MMP-9 expression in gastric cancer.
Neoplasms
Clinical and prognostic role of matrix metalloproteinase-2, -9 and their inhibitors in breast cancer and liver diseases: A review.
Neoplasms
Clinical implications of HER-2/neu overexpression and proteolytic activity imbalance in breast cancer.
Neoplasms
Clinical manifestations of atherosclerosis in an elderly population are related to plasma neopterin, NGAL and endothelin-1, but not to Chlamydia pneumoniae serology.
Neoplasms
Clinical relevance of cyclooxygenase-2 and matrix metalloproteinases (MMP-2 and MT1-MMP) in human breast cancer tissue.
Neoplasms
Clinical Relevance of Increased Endothelial and Mesothelial Expression of Proangiogenic Proteases and VEGFA in the Omentum of Patients with Metastatic Ovarian High-Grade Serous Carcinoma.
Neoplasms
Clinical significance of expression of membrane type 1 matrix metalloproteinase and matrix metalloproteinase-2 in human head and neck squamous cell carcinoma.
Neoplasms
Clinical significance of matrix metalloproteinase-2 in cancer of uterine cervix: a semiquantitative study of immunoreactivities using tissue array.
Neoplasms
Clinical significance of matrix metalloproteinase-2 in endometrial cancer: A systematic review and meta-analysis.
Neoplasms
Clinical significance of plasma MMP-2 and MMP-9 levels as biomarkers for tumor expression in breast cancer patients in Egypt.
Neoplasms
Clinical significance of SCCRO (DCUN1D1) in prostate cancer and its proliferation-inhibiting effect on Lncap cells.
Neoplasms
Clinical significance of secreted protein acidic and rich in cystein in esophageal carcinoma and its relation to carcinoma progression.
Neoplasms
Clinical significance of serum levels of matrix metalloproteinase 2 (MMP-2) and its tissue inhibitor (TIMP-2) in gastric cancer.
Neoplasms
Clinical significance of tissue levels of matrix metalloproteinases and tissue inhibitors of metalloproteinases in gastric cancer.
Neoplasms
Clinical study of systemic chemotherapy combined with bronchoscopic interventional cryotherapy in the treatment of lung cancer.
Neoplasms
Clinical Study of Tumor Angiogenesis and Perfusion Imaging Using Multi-slice Spiral Computed Tomography for Breast Cancer.
Neoplasms
Clinicohistopathological implications of MMP/VEGF expression in retinoblastoma: a combined meta-analysis and bioinformatics analysis.
Neoplasms
Clinicopathologic and Prognostic Significance of Gelatinase A in Tunisian Colorectal Cancer: A Case-Control Study.
Neoplasms
Clinicopathologic and prognostic significance of matrix metalloproteinases in rectal cancer.
Neoplasms
Clinicopathologic evaluation of immunohistochemical CD147 and MMP-2 expression in differentiated thyroid carcinoma.
Neoplasms
Clinicopathologic significance of plasma matrix metalloproteinase-2 and -9 levels in patients with undifferentiated nasopharyngeal carcinoma.
Neoplasms
Clinicopathological and biological significance of human voltage-gated proton channel Hv1 over-expression in breast cancer.
Neoplasms
Clinicopathological assessment and quantitative estimation of the matrix metalloproteinases MMP-2 and MMP-7 and the inhibitors TIMP-1 and TIMP-2 in colorectal carcinoma tissue samples.
Neoplasms
Clinicopathological significance of E-cadherin, VEGF, and MMPs in gastric cancer.
Neoplasms
Clinicopathological significance of matrix metalloproteinase 2 protein expression in patients with renal cell carcinoma: A case-control study and meta-analysis.
Neoplasms
Clinicopathological Significance of Matrix Metalloproteinase-2 Protein Expression in Renal Cell Carcinoma Patients.
Neoplasms
Clinicopathological significance of MMP-2 and its specific inhibitor TIMP-2 in gastric cancer.
Neoplasms
Clinicopathological significance of the gene expression of matrix metalloproteinases and reversion-inducing cysteine-rich protein with Kazal motifs in patients with colorectal cancer: MMP-2 gene expression is a useful predictor of liver metastasis from colorectal cancer.
Neoplasms
Cloning of a 72 kDa matrix metalloproteinase (gelatinase) from chicken embryo fibroblasts using gene family PCR: expression of the gelatinase increases upon malignant transformation.
Neoplasms
CMT-3, a non-antimicrobial tetracycline (TC), inhibits MT1-MMP activity: relevance to cancer.
Neoplasms
Co-chaperones TIMP2 and AHA1 Competitively Regulate Extracellular HSP90:Client MMP2 Activity and Matrix Proteolysis.
Neoplasms
Co-evolution of cancer microenvironment reveals distinctive patterns of gastric cancer invasion: laboratory evidence and clinical significance.
Neoplasms
Co-regulated expression of matrix metalloproteinase-2 and transforming growth factor-beta in melanoma development and progression.
Neoplasms
CO2 Pneumoperitoneum Effects on Molecular Markers of Tumor Invasiveness in SH-SY5Y Neuroblastoma Cells.
Neoplasms
Coaxial extrusion bioprinted shell-core hydrogel microfibers mimic glioma microenvironment and enhance the drug resistance of cancer cells.
Neoplasms
Cobalt chloride-induced hypoxia modulates the invasive potential and matrix metalloproteinases of primary and metastatic breast cancer cells.
Neoplasms
Coexpression of glucose transporter 1 and matrix metalloproteinase-2 in human cancers.
Neoplasms
Collagen-based co-culture for invasive study on cancer cells-fibroblasts interaction.
Neoplasms
Collagenase is expressed by rabbit VX2 tumour cells in syngeneic and xenogeneic hosts.
Neoplasms
Collagenase IV and clusterin-modified polycaprolactone-polyethylene glycol nanoparticles for penetrating dense tumor tissues.
Neoplasms
Collagenase-3 expression is associated with advanced local invasion in human squamous cell carcinomas of the larynx.
Neoplasms
Colon cancer cell-derived tumor necrosis factor-alpha mediates the tumor growth-promoting response in macrophages by up-regulating the colony-stimulating factor-1 pathway.
Neoplasms
Colony-stimulating factor-1 antibody reverses chemoresistance in human mcf-7 breast cancer xenografts.
Neoplasms
Colony-stimulating factor-1 antisense treatment suppresses growth of human tumor xenografts in mice.
Neoplasms
Colony-stimulating factor-1 blockade by antisense oligonucleotides and small interfering RNAs suppresses growth of human mammary tumor xenografts in mice.
Neoplasms
Colorectal Cancer and Mitochondrial Dysfunctions of the Adjunct Adipose Tissues: A Case Study.
Neoplasms
Colorectal cancer or colon and rectal cancer? Clinicopathological comparison between colonic and rectal carcinomas.
Neoplasms
Combination Efficacy of Astragalus membranaceus and Curcuma wenyujin at Different Stages of Tumor Progression in an Imageable Orthotopic Nude Mouse Model of Metastatic Human Ovarian Cancer Expressing Red Fluorescent Protein.
Neoplasms
Combination of paclitaxel- and retinoic acid-incorporated nanoparticles for the treatment of CT-26 colon carcinoma.
Neoplasms
Combination of pembrolizumab and 125I attenuates the aggressiveness of non-small cell lung cancer.
Neoplasms
Combination of retinoic acid and ursodeoxycholic acid attenuates liver injury in bile duct-ligated rats and human hepatic cells.
Neoplasms
Combinatorial interactions of p53, activating protein-2, and YB-1 with a single enhancer element regulate gelatinase A expression in neoplastic cells.
Neoplasms
Combined delivery of salinomycin and docetaxel by dual-targeting gelatinase nanoparticles effectively inhibits cervical cancer cells and cancer stem cells.
Neoplasms
Combined evaluation of matrix metalloproteinases and their inhibitors has better clinical utility in oral cancer.
Neoplasms
Combined therapeutic effect and molecular mechanisms of metformin and cisplatin in human lung cancer xenografts in nude mice.
Neoplasms
Combined treatment with serine protease inhibitor aprotinin and matrix metalloproteinase inhibitor Batimastat (BB-94) does not prevent invasion of human esophageal and ovarian carcinoma cells in vivo.
Neoplasms
Comparative analysis of matrix metalloproteinases by immunocytochemistry, immunohistochemistry and zymography in human primary brain tumours.
Neoplasms
Comparative Analysis of P63, Maspin and Matrix Metalloproteinase 2 Expression in Mucoepidermoid Carcinoma and Adenoid Cystic Carcinoma of Salivary Glands.
Neoplasms
Comparative analysis of protein expression in differentiated thyroid tumours: a multicentre study.
Neoplasms
Comparative analysis of the expression of metalloproteases (MMP-2, MMP-9, MMP-11 and MMP-13) and the tissue inhibitor of metalloprotease 3 (TIMP-3) between previous negative biopsies and radical prostatectomies.
Neoplasms
Comparative effects of EGCG, green tea and a nutrient mixture on the patterns of MMP-2 and MMP-9 expression in cancer cell lines.
Neoplasms
Comparative expression of matrix metalloproteinases in internal malignancies and paired cutaneous metastatic lesions.
Neoplasms
Comparative study of MMP-2 (matrix metalloproteinase 2) immune expression in normal uterine cervix, intraepithelial neoplasias, and squamous cells cervical carcinoma.
Neoplasms
Comparing biocompatibility of gingival fibroblasts and bacterial strains on a different modified titanium discs.
Neoplasms
Comparison between the gastric cancer cell line MKN-45 and the high-potential peritoneal dissemination gastric cancer cell line MKN-45P.
Neoplasms
Comparison of fibrin glue and Vicryl sutures in conjunctival autografting for pterygium surgery.
Neoplasms
Comparison of matrix metalloproteinase expression between primary tumors with or without liver metastasis in pancreatic and colorectal carcinomas.
Neoplasms
Comparison of responsiveness to cancer development and anti-cancer drug in three different C57BL/6N stocks.
Neoplasms
Components of the RANK/RANKL/OPG system, IL-6, IL-8, IL-16, MMP-2, and calcitonin in the sera of patients with bone tumors.
Neoplasms
Comprehensive profiling and localisation of the matrix metalloproteinases in urothelial carcinoma.
Neoplasms
Comprehensively enhanced delivery cascade by transformable beaded nanofibrils for pancreatic cancer therapy.
Neoplasms
Concentration of metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in the serum of patients with benign and malignant thyroid tumours treated surgically.
Neoplasms
Concomitant inhibition of epidermal growth factor and vascular endothelial growth factor receptor tyrosine kinases reduces growth and metastasis of human salivary adenoid cystic carcinoma in an orthotopic nude mouse model.
Neoplasms
Concomitant reduction of matrix metalloproteinase-2 secretion and intracellular reactive oxygen species following anti-sense inhibition of telomerase activity in PC-3 prostate carcinoma cells.
Neoplasms
Conjunctival expression of matrix metalloproteinase and pro-inflammatory cytokine genes following trichiasis surgery.
Neoplasms
Constitutive expression of a 92-kD gelatinase (type V collagenase) by rheumatoid synovial fibroblasts and its induction in normal human fibroblasts by inflammatory cytokines.
Neoplasms
Construction and clinical significance of a predictive system for prognosis of hepatocellular carcinoma.
Neoplasms
Construction of a sensitive protease sensor with DNA-peptide conjugates for single-molecule detection of multiple matrix metalloproteinases.
Neoplasms
Contribution of host MMP-2 and MMP-9 to promote tumor vascularization and invasion of malignant keratinocytes.
Neoplasms
Contribution of in vitro comparison of colorectal carcinoma cells from primary and metastatic lesions to elucidation of mechanisms of tumor progression and response to anticancer therapy.
Neoplasms
Contribution of Matrix Metalloproteinase-2 Promoter Genotypes to Nasopharyngeal Cancer Susceptibility and Metastasis in Taiwan.
Neoplasms
Control of long-distance cell-to-cell communication and autophagosome transfer in squamous cell carcinoma via tunneling nanotubes.
Neoplasms
Control of lymphatic and hematogenous metastasis of a rat mammary carcinoma by the matrix metalloproteinase inhibitor batimastat (BB-94).
Neoplasms
Control of type IV collagenase activity by components of the urokinase-plasmin system: a regulatory mechanism with cell-bound reactants.
Neoplasms
Cooperative regulation of the invasive and metastatic phenotypes by different domains of the type I insulin-like growth factor receptor beta subunit.
Neoplasms
Coordinate action of membrane-type matrix metalloproteinase -1 (MT1-MMP) and MMP-2 enhances pericellular proteolysis and invasion.
Neoplasms
Coordinate enhancement of gelatinase A mRNA and activity levels in human fibroblasts in response to breast-adenocarcinoma cells.
Neoplasms
Coordinated targeting of MMP-2/MMP-9 by miR-296-3p/FOXCUT exerts tumor-suppressing effects in choroidal malignant melanoma.
Neoplasms
Cooverexpression of ERBB1 and ERBB4 receptors predicts poor clinical outcome in pN+ oral squamous cell carcinoma with extranodal spread.
Neoplasms
Core-Shell Distinct Nanodrug Showing On-Demand Sequential Drug Release To Act on Multiple Cell Types for Synergistic Anticancer Therapy.
Neoplasms
Correlation and prognostic significance of MMP-2 and TFPI-2 differential expression in pancreatic carcinoma.
Neoplasms
Correlation between B7-H3 expression and matrix metalloproteinases 2 expression in pancreatic cancer.
Neoplasms
Correlation between expression of matrix metalloproteinase-2 (MMP-2), and matrix metalloproteinase-9 (MMP-9) and angiogenesis in colorectal adenocarcinoma.
Neoplasms
Correlation between MMP2 expression in lung cancer tissues and clinical parameters: a retrospective clinical analysis.
Neoplasms
Correlation between vascular endothelial growth factor-C expression and invasion phenotype in cervical carcinomas.
Neoplasms
Correlation of matrix metalloproteinase-2, -9, tissue inhibitor-1 of matrix metalloproteinase and CD44 variant 6 in head and neck cancer metastasis.
Neoplasms
Correlation of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinase expression in ileal carcinoids, lymph nodes and liver metastasis with prognosis and survival.
Neoplasms
Correlation of matrix metalloproteinases-2 and -9 with proinflammatory cytokines in Guillain-Barré syndrome.
Neoplasms
Correlation of RECK with matrix metalloproteinase-2 in regulation of trophoblast invasion of early pregnancy.
Neoplasms
Correlation of reversion-inducing cysteine-rich protein with kazal motifs (RECK) and extracellular matrix metalloproteinase inducer (EMMPRIN), with MMP-2, MMP-9, and survival in colorectal cancer.
Neoplasms
Correlation of the in situ detection of polymerase chain reaction-amplified metalloproteinase complementary DNAs and their inhibitors with prognosis in cervical carcinoma.
Neoplasms
Correlation of tumor- and stromal-derived MT1-MMP expression with progression of human ovarian tumors in SCID mice.
Neoplasms
Correlations of serum VEGF and MMP-2 levels with CLM in CRC patients and effects of TACE on their expressions.
Neoplasms
Correspondence re: C. F. M. Sier et al., Enhanced urinary gelatinase activities (matrix metalloproteinases 2 and 9) are associated with early-stage bladder carcinoma: a comparison with clinically used tumor markers. Clin. Cancer Res., 6: 2333-2340, 2000.
Neoplasms
Correspondence re: N-B. Liabakk et al., matrix metalloprotease 2 (MMP-2) and matrix metalloprotease 9 (MMP-9) type IV collagenases in colorectal cancer. Cancer Res., 56: 190-196, 1966.
Neoplasms
Corydalis hendersonii Hemsl. protects against myocardial injury by attenuating inflammation and fibrosis via NF-?B and JAK2-STAT3 signaling pathways.
Neoplasms
Cranial burr hole with erythropoietin administration induces reverse arteriogenesis from the enriched extracranium.
Neoplasms
Cratoxy formosum leaf extract inhibits proliferation and migration of human breast cancer MCF-7 cells.
Neoplasms
Critical appraisal of the use of matrix metalloproteinase inhibitors in cancer treatment.
Neoplasms
CSE1L/CAS, the cellular apoptosis susceptibility protein, enhances invasion and metastasis but not proliferation of cancer cells.
Neoplasms
Cucurbitacin B Enhances the Anticancer Effect of Imatinib Mesylate Through Inhibition of MMP-2 Expression in MCF-7 and SW480 Tumor Cell Lines.
Neoplasms
Cudratricusxanthone G inhibits human colorectal carcinoma cell invasion by MMP-2 down-regulation through suppressing activator protein-1 activity.
Neoplasms
Curcumin ameliorates left ventricular function in rabbits with pressure overload: inhibition of the remodeling of the left ventricular collagen network associated with suppression of myocardial tumor necrosis factor-alpha and matrix metalloproteinase-2 expression.
Neoplasms
Curcumin sensitizes TRAIL-resistant xenografts: molecular mechanisms of apoptosis, metastasis and angiogenesis.
Neoplasms
Curcumin suppresses invasiveness and vasculogenic mimicry of squamous cell carcinoma of the larynx through the inhibition of JAK-2/STAT-3 signaling pathway.
Neoplasms
Curcumin suppresses tumor necrosis factor-?-induced matrix metalloproteinase-2 expression and activity in rat vascular smooth muscle cells via the NF-?B pathway.
Neoplasms
Curcumin, a potential inhibitor of MMP-2 in human laryngeal squamous carcinoma cells HEp2.
Neoplasms
Curcumol inhibits lung adenocarcinoma growth and metastasis via inactivation of PI3K/AKT and Wnt/ß-catenin pathway.
Neoplasms
Current Biochemical Applications and Future Prospects of Chlorotoxin in Cancer Diagnostics and Therapeutics.
Neoplasms
CXCR4 and matrix metalloproteinase-2 are involved in mesenchymal stromal cell homing and engraftment to tumors.
Neoplasms
CXCR4 pharmacogical inhibition reduces bone and soft tissue metastatic burden by affecting tumor growth and tumorigenic potential in prostate cancer preclinical models.
Neoplasms
Cyclic AMP decreases chemotaxis, invasiveness and lung colonization of H-ras transformed mouse fibroblasts.
Neoplasms
Cyclin-dependent kinase 9 is required for tumor necrosis factor-alpha-stimulated matrix metalloproteinase-9 expression in human lung adenocarcinoma cells.
Neoplasms
Cyclooxygenase-2 expression correlates with membrane-type-1 matrix metalloproteinase expression in colorectal cancer tissue.
Neoplasms
Cyclooxygenase-2 inhibitor prevents radiation-enhanced infiltration of F98 glioma cells in brain of Fischer rat.
Neoplasms
Cysteinyl leukotriene receptor type 1 antagonist montelukast protects against injury of blood-brain barrier.
Neoplasms
Cystic vestibular schwannomas: a possible role of matrix metalloproteinase-2 in cyst development and unfavorable surgical outcome.
Neoplasms
Cytokine and matrix metalloproteinase expression in pigmented villonodular synovitis may mediate bone and cartilage destruction.
Neoplasms
Cytokine regulation of gelatinase production by head and neck squamous cell carcinoma: the role of tumor necrosis factor-alpha.
Neoplasms
Cytokine, chemokine, and matrix metalloproteinase response after sulfur mustard injury to weanling pig skin.
Neoplasms
Cytokine-mediated regulation of human leukocyte gelatinases and role in arthritis.
Neoplasms
Cytokine-stimulated human vascular smooth muscle cells synthesize a complement of enzymes required for extracellular matrix digestion.
Neoplasms
Cytokines regulate gelatinase A and B (matrix metalloproteinase 2 and 9) activity in cultured rat astrocytes.
Neoplasms
Cytokines regulate matrix metalloproteinases and migration in cardiac fibroblasts.
Neoplasms
Cytokines, inducers and inhibitors modulate MMP-2 and MMP?9 secretion by human Fanconi anemia immortalized fibroblasts.
Neoplasms
Cytokines, matrix metalloproteases, angiogenic and growth factors in tears of normal subjects and vernal keratoconjunctivitis patients.
Neoplasms
Cytotoxic Fusicoccane-Type Diterpenoids from Streptomyces violascens Isolated from Ailuropoda melanoleuca Feces.
Neoplasms
Decreased TNF Levels and Improved Retinal Ganglion Cell Survival in MMP-2 Null Mice Suggest a Role for MMP-2 as TNF Sheddase.
Neoplasms
Degradation of tenascin-C and activity of matrix metalloproteinase-2 are associated with tumor recurrence in early stage non-small cell lung cancer.
Neoplasms
Dehydroandrographolide inhibits oral cancer cell migration and invasion through NF-?B-, AP-1-, and SP-1-modulated matrix metalloproteinase-2 inhibition.
Neoplasms
Delineating the molecular basis of the inactivity of tissue inhibitor of metalloproteinase-2 against tumor necrosis factor-alpha-converting enzyme.
Neoplasms
Delphinidin suppresses PMA-induced MMP-9 expression by blocking the NF-?B activation through MAPK signaling pathways in MCF-7 human breast carcinoma cells.
Neoplasms
Dendropanax dentiger (Harms) Merr. root and its major constituents exert therapeutic effect on adjuvant-induced arthritis in rats.
Neoplasms
Density-dependent regulation of cell-surface association of matrix metalloproteinase-2 (MMP-2) in breast-carcinoma cells.
Neoplasms
Depletion of Hepatic Macrophages Aggravates Liver Lesions Induced in Rats by Thioacetamide (TAA).
Neoplasms
Depsipeptide a histone deacetlyase inhibitor down regulates levels of matrix metalloproteinases 2 and 9 mRNA and protein expressions in lung cancer cells (A549).
Neoplasms
Derlin-1 Is Overexpressed in Non-Small Cell Lung Cancer and Promotes Cancer Cell Invasion via EGFR-ERK-Mediated Up-Regulation of MMP-2 and MMP-9.
Neoplasms
Design and characterization of a metalloproteinase inhibitor-tethered resin for the detection of active MMPs in biological samples.
Neoplasms
Design and Proof of Programmed 5-Aminolevulinic Acid Prodrug Nanocarriers for Targeted Photodynamic Cancer Therapy.
Neoplasms
Design and synthesis of MMP inhibitors with appended fluorescent tags for imaging and visualization of matrix metalloproteinase enzymes.
Neoplasms
Design of radiolabeled gelatinase inhibitor peptide ((99m)Tc-CLP) and evaluation in rats.
Neoplasms
Desmoplastic basal cell carcinomas possess unique basement membrane-degrading properties.
Neoplasms
Desmoplastic response in scirrhous gastric carcinoma: imbalance between collagen synthesis and degradation.
Neoplasms
Detection and localization of mRNAs encoding matrix metalloproteinases and their tissue inhibitor in human breast pathology.
Neoplasms
Detection and Molecular Staging of Bladder Cancer Using Real-Time RT-PCR for Gelatinases (MMP-2, MMP-9) and TIMP-2 in Peripheral Blood.
Neoplasms
Detection of differentially expressed gelatinase A in metastatic and non-metastatic subpopulations of tumor cells by target RNA arbitrarily primed polymerase chain reaction (TRAP-PCR).
Neoplasms
Detection of Early Murine Colorectal Cancer by MMP-2/-9-Guided Fluorescence Endoscopy.
Neoplasms
Detection of matrix metalloproteinases in canine mammary tumours: analysis by immunohistochemistry and zymography.
Neoplasms
Detection of migration of locally implanted AC133+ stem cells by cellular magnetic resonance imaging with histological findings.
Neoplasms
Detection of MMP-2 and MMP-9 Activity in Vivo with a Triple-Helical Peptide Optical Probe.
Neoplasms
Detection of osteoarthritis in dogs by metabolic, pro-inflammatory and degenerative synovial fluid biomarkers and traditional radiographic screening: A pilot study.
Neoplasms
Determination of gelatinase A using a modified indirect hemagglutination assay in human prostate cancer screening and assessment of its correlation with prostate-specific antigen parameters.
Neoplasms
Determination of imbalance between MMP-2 and TIMP-2 in human neuroblastoma by reverse-transcription polymerase chain reaction and its correlation with tumor progression.
Neoplasms
Development of a biomarker panel to predict cardiac resynchronization therapy response: Results from the SMART-AV trial.
Neoplasms
Development of a gene/drug dual delivery system for brain tumor therapy: potent inhibition via RNA interference and synergistic effects.
Neoplasms
Development of a Novel PET Tracer [18F]AlF-NOTA-C6 Targeting MMP2 for Tumor Imaging.
Neoplasms
Development of a pH-responsive polymersome inducing endoplasmic reticulum stress and autophagy blockade.
Neoplasms
Development of anti-matrix metalloproteinase-2 (MMP-2) nanobodies as potential therapeutic and diagnostic tools.
Neoplasms
Development of MRI/NIRF 'activatable' multimodal imaging probe based on iron oxide nanoparticles.
Neoplasms
Development of Novel Animal Model for Studying Scoliosis Using a Noninvasive Method and Its Validation through Gene-Expression Analysis.
Neoplasms
Development of upconversion nanoparticle-conjugated indium phosphide quantum dot for matrix metalloproteinase-2 cancer transformation sensing.
Neoplasms
Dexamethasone regulation of matrix metalloproteinase expression in CNS vascular endothelium.
Neoplasms
Dextran Sulfate Effects EMT of Human Gastric Cancer Cells by Reducing HIF-1?/ TGF-?.
Neoplasms
Diagnostic Power of Cytokine M-CSF, Metalloproteinase 2 (MMP-2) and Tissue Inhibitor-2 (TIMP-2) in Cervical Cancer Patients Based on ROC Analysis.
Neoplasms
Dicer suppresses MMP-2-mediated invasion and VEGFA-induced angiogenesis and serves as a promising prognostic biomarker in human clear cell renal cell carcinoma.
Neoplasms
Diethyldithiocarbamate prolongs survival of mice in a lipopolysaccharide-induced endotoxic shock model: evidence for multiple mechanisms.
Neoplasms
Different mRNA and protein expression of matrix metalloproteinases 2 and 9 and tissue inhibitor of metalloproteinases 1 in benign and malignant prostate tissue.
Neoplasms
Different patterns of gelatinolytic activity in pituitary macro- and microadenomas.
Neoplasms
Different Protein Expressions between Peripheral Ameloblastoma and Oral Basal Cell Carcinoma Occurred at the Same Mandibular Molar Area.
Neoplasms
Differential effects of trichostatin A on gelatinase A expression in 3T3 fibroblasts and HT-1080 fibrosarcoma cells: implications for use of TSA in cancer therapy.
Neoplasms
Differential effects of tumor necrosis factor-? on matrix metalloproteinase-2 expression in human myometrial and uterine leiomyoma smooth muscle cells.
Neoplasms
Differential expression and activity status of MMP-1, MMP-2 and MMP-9 in tumor and stromal cells of squamous cell carcinomas of the lung.
Neoplasms
Differential expression and origin of membrane-type 1 and 2 matrix metalloproteinases (MT-MMPs) in association with MMP2 activation in injured human livers.
Neoplasms
Differential expression of Low density lipoprotein Receptor-related Protein 1 (LRP-1) and matrix metalloproteinase-9 (MMP-9) in prostate gland: From normal to malignant lesions.
Neoplasms
Differential expression of matrilysin-1 (MMP-7), 92 kD gelatinase (MMP-9), and metalloelastase (MMP-12) in oral verrucous and squamous cell cancer.
Neoplasms
Differential expression of matrix metalloproteinase (MMP)-2, MMP-9 and tissue inhibitor of metalloproteinase (TIMP)-1 and TIMP-2 in non-melanoma skin cancer: implications for tumour progression.
Neoplasms
Differential expression of matrix metalloproteinase (MMP)-2, MMP-9, and membrane type 1-MMP in hepatocellular and pancreatic adenocarcinoma: implications for tumor progression and clinical prognosis.
Neoplasms
Differential expression of matrix metalloproteinase-2 by fibroblasts in co-cultures with keratinocytes, basal cell carcinoma and melanoma.
Neoplasms
Differential expression of matrix metalloproteinase-2 expression in disseminated tumor cells and micrometastasis in bone marrow of patients with nonmetastatic and metastatic prostate cancer: theoretical considerations and clinical implications-an immunocytochemical study.
Neoplasms
Differential expression of matrix metalloproteinases 2 and 9 by glial Müller cells: response to soluble and extracellular matrix-bound tumor necrosis factor-alpha.
Neoplasms
Differential expression of matrix metalloproteinases and their inhibitors in non-small cell lung cancer.
Neoplasms
Differential expression of membrane-type matrix metalloproteinase and its correlation with gelatinase A activation in human malignant brain tumors in vivo and in vitro.
Neoplasms
Differential inhibition of gelatinase activity in human colon adenocarcinoma cells by Aloe vera and Aloe arborescens extracts.
Neoplasms
DIFFERENTIAL INHIBITION OF TUMOUR CELL-INDUCED PLATELET AGGREGATION BY NICOTINATE ASPIRIN PRODRUG (ST0702) AND ASPIRIN.
Neoplasms
Differential regulation of matrix metalloproteinases in human cancer cells by exogenous factors.
Neoplasms
Differential regulation of membrane type 1-matrix metalloproteinase activity by ERK 1/2- and p38 MAPK-modulated tissue inhibitor of metalloproteinases 2 expression controls transforming growth factor-beta1-induced pericellular collagenolysis.
Neoplasms
Differential regulation of MMP-9 and TIMP-2 expression in malignant melanoma developed in metallothionein/RET transgenic mice.
Neoplasms
Differential roles of matrix metalloproteinase-9 and -2, depending on proliferation or differentiation of retinoblastoma cells.
Neoplasms
Diffuse malignant mesothelioma of the peritoneum: a clinicopathological study of 35 patients treated locoregionally at a single institution.
Neoplasms
Dihomo-?-linolenic acid inhibits growth of xenograft tumors in mice bearing human pancreatic cancer cells (BxPC-3) transfected with delta-5-desaturase shRNA.
Neoplasms
Dimethyloxalylglycine, a small molecule, synergistically increases the homing and angiogenic properties of human mesenchymal stromal cells when cultured as 3D spheroids.
Neoplasms
Direct anti-metastatic efficacy by the DNA enzyme Dz13 and downregulated MMP-2, MMP-9 and MT1-MMP in tumours.
Neoplasms
Direct cell-cell interaction enhances pro-MMP-2 production and activation in co-culture of laryngeal cancer cells and fibroblasts: involvement of EMMPRIN and MT1-MMP.
Neoplasms
Discoidin domain receptor-1a (DDR1a) promotes glioma cell invasion and adhesion in association with matrix metalloproteinase-2.
Neoplasms
Discovery of selective hydroxamic acid inhibitors of tumor necrosis factor-alpha converting enzyme.
Neoplasms
Disrupted Balance of MMPs/TIMPs in Gastric Carcinogenesis-Paradoxical Low MMP-2 Expression in Tumor and Stromal Compartments as a Potential Marker of Unfavorable Outcome.
Neoplasms
Disruption of angiogenesis by PEX, a noncatalytic metalloproteinase fragment with integrin binding activity.
Neoplasms
Disruption of matrix metalloproteinase 2 binding to integrin alpha vbeta 3 by an organic molecule inhibits angiogenesis and tumor growth in vivo.
Neoplasms
Disseminated tumor cells in bone marrow of gastric cancer patients: correlation with tumor hypoxia and clinical relevance.
Neoplasms
Distinct endobronchial expression of matrix-metalloproteinases (MMP) and their endogenous inhibitors in lung cancer.
Neoplasms
Distinct Functionality of Tumor Cell-Derived Gelatinases during Formation of Liver Metastases.
Neoplasms
Distinct patterns of matrix metalloproteinase-2 and -9 expression in normal human cell lines.
Neoplasms
Distinct progression-associated expression of tumor and stromal MMPs in HaCaT skin SCCs correlates with onset of invasion.
Neoplasms
Disulfiram suppresses invasive ability of osteosarcoma cells via the inhibition of MMP-2 and MMP-9 expression.
Neoplasms
Diverse role of MMP-2 and MMP-9 in the clinicopathological behavior of Hodgkin's lymphoma.
Neoplasms
Do Young Patients with Colorectal Cancer Have a Poorer Prognosis than Old Patients?
Neoplasms
Dominant-negative transcription factor AP-2 augments SB-2 melanoma tumor growth in vivo.
Neoplasms
Dopamine D2 receptor antagonist sulpiride enhances dexamethasone responses in the treatment of drug-resistant and metastatic breast cancer.
Neoplasms
Down-Regulation of MT1-MMP expression by the alpha3 chain of type IV collagen inhibits bronchial tumor cell line invasion.
Neoplasms
Down-regulation of tumour gelatinase/inhibitor balance and preservation of tumour endothelium by an anti-metastatic ruthenium complex.
Neoplasms
Down-regulation of vascular endothelial growth factor by tissue inhibitor of metalloproteinase-2: effect on in vivo mammary tumor growth and angiogenesis.
Neoplasms
Downregulation of cancer stem cell properties via mTOR signaling pathway inhibition by rapamycin in nasopharyngeal carcinoma.
Neoplasms
Downregulation of FOXP3 inhibits invasion and immune escape in cholangiocarcinoma.
Neoplasms
Downregulation of G3BPs inhibits the growth, migration and invasion of human lung carcinoma H1299 cells by suppressing the Src/FAK-associated signaling pathway.
Neoplasms
Downregulation of matrix metalloproteinase-2 (MMP-2) utilizing adenovirus-mediated transfer of small interfering RNA (siRNA) in a novel spinal metastatic melanoma model.
Neoplasms
Downregulation of microRNA-1246 inhibits tumor growth and promotes apoptosis of cervical cancer cells by targeting thrombospondin-2.
Neoplasms
Downregulation of PART1 Inhibits Proliferation and Differentiation of Hep3B Cells by Targeting hsa-miR-3529-3p/FOXC2 Axis.
Neoplasms
Downregulation of reversion-inducing cysteine-rich protein with Kazal motifs in malignant melanoma: inverse correlation with membrane-type 1-matrix metalloproteinase and tissue inhibitor of metalloproteinase 2.
Neoplasms
Downregulation of SFRP5 expression and its inverse correlation with those of MMP-7 and MT1-MMP in gastric cancer.
Neoplasms
Downregulation of the RECK-tumor and metastasis suppressor gene in glioma invasiveness.
Neoplasms
Doxorubicin and Trifolium pratense L. (Red clover) extract synergistically inhibits brain and lung metastases in 4T1 tumor-bearing BALB/c mice.
Neoplasms
Dual Action of NAMI-A in inhibition of solid tumor metastasis: selective targeting of metastatic cells and binding to collagen.
Neoplasms
Dual roles of tumour cells-derived matrix metalloproteinase 2 on brain tumour growth and invasion.
Neoplasms
Dual targeting of integrin ?v?3 and matrix metalloproteinase-2 for optical imaging of tumors and chemotherapeutic delivery.
Neoplasms
Dual-drug nanomedicine with hydrophilic F127-modified magnetic nanocarriers assembled in amphiphilic gelatin for enhanced penetration and drug delivery in deep tumor tissue.
Neoplasms
Dual-Responsive Size-Shrinking Nanocluster with Hierarchical Disassembly Capability for Improved Tumor Penetration and Therapeutic Efficacy.
Neoplasms
Dual-Sensitive PEG-Sheddable Nanodrug Hierarchically Incorporating PD-L1 Antibody and Zinc Phthalocyanine for Improved Immuno-Photodynamic Therapy.
Neoplasms
Dual-targeting and microenvironment-responsive micelles as a gene delivery system to improve the sensitivity of glioma to radiotherapy.
Neoplasms
Dulcitol suppresses proliferation and migration of hepatocellular carcinoma via regulating SIRT1/p53 pathway.
Neoplasms
E-cadherin, MMP-2, and MMP-9 as prognostic markers in penile cancer: Analysis of 125 patients.
Neoplasms
Early acquisition of gelatinolytic activity in carcinogenesis of the uterine cervix.
Neoplasms
Early detection of head and neck cancer: development of a novel screening tool using multiplexed immunobead-based biomarker profiling.
Neoplasms
Early effects of laparotomy and laparoscopy on bacterial behavior and proinflammatory cytokines on bacterial peritonitis in rats I: Escherichia coli.
Neoplasms
Early laminar events involving endothelial activation in horses with black walnut- induced laminitis.
Neoplasms
Edaravone, a novel antidote against lung injury and pulmonary fibrosis induced by paraquat?
Neoplasms
Effect of androgen blockade on HER-2 and matrix metalloproteinase-2 expression on bone marrow micrometastasis and stromal cells in men with prostate cancer.
Neoplasms
Effect of arginine on angiogenesis induced by human colon cancer: in vitro and in vivo studies.
Neoplasms
Effect of AT2 blockade on cardiac hypertrophy as induced by high dietary salt in the proatrial natriuretic peptide (ANP) gene-disrupted mouse.
Neoplasms
Effect of c-myc, Ki-67, MMP-2 and VEGF expression on prognosis of hepatocellular carcinoma patients undergoing tumor resection.
Neoplasms
Effect of CO2 pneumoperitoneum on the proliferation of human ovarian cancer cell line SKOV-3 and the expression of NM23-H1 and MMP-2.
Neoplasms
Effect of combined cyclooxygenase-2 and matrix metalloproteinase inhibition on human sarcoma xenografts.
Neoplasms
Effect of Conjugated Linoleic Acid Supplementation on Inflammatory Factors and Matrix Metalloproteinase Enzymes in Rectal Cancer Patients Undergoing Chemoradiotherapy.
Neoplasms
Effect of doxycycline on proliferation, MMP production, and adhesion in LAM-related cells.
Neoplasms
Effect of Etiasa on the expression of matrix metalloproteinase-2 and tumor necrosis factor-? in a rat model of ulcerative colitis.
Neoplasms
Effect of hGC-MSCs from human gastric cancer tissue on cell proliferation, invasion and epithelial-mesenchymal transition in tumor tissue of gastric cancer tumor-bearing mice.
Neoplasms
Effect of isofebrifugine on the proliferation and invasion of human gastric cancer cells via MMP.
Neoplasms
Effect of matrix metalloproteinase inhibitors on tumor growth and spontaneous metastasis.
Neoplasms
Effect of metallothioneins on transformation of gelatinase A from human fibroblast WI-38 cells.
Neoplasms
Effect of Sirtuin 1 inhibition on matrix metalloproteinase 2 and Forkhead box O3a expression in breast cancer cells.
Neoplasms
Effect of thalidomide on cardiac remodeling in chronic heart failure: results of a double-blind, placebo-controlled study.
Neoplasms
Effect of troglitazone on tumor growth and pulmonary metastasis development of the mouse osteosarcoma cell line LM8.
Neoplasms
Effects of 17beta-estradiol on the expression of membrane type 1 matrix metalloproteinase (MT1-MMP) and MMP-2 in human osteoblastic MG-63 cell cultures.
Neoplasms
Effects of Coriandrum sativum on Migration and Invasion Abilities of Cancer Cells.
Neoplasms
Effects of curcumin on the role of MMP-2 in endometrial cancer cell proliferation and invasion.
Neoplasms
Effects of doxycycline on intestinal ischemia reperfusion injury induced by abdominal compartment syndrome in a rat model.
Neoplasms
Effects of EGF and TGF-alpha on invasion and proteinase expression of uterine cervical adenocarcinoma OMC-4 cells.
Neoplasms
Effects of Enzymatic Activation on the Distribution of Fluorescently Tagged MMP-2 Cleavable Peptides in Cancer Cells and Spheroids.
Neoplasms
Effects of epidermal growth factor on invasiveness through the extracellular matrix in high- and low-metastatic clones of RCT sarcoma in vitro.
Neoplasms
Effects of genistein and 2-methoxyestradiol on matrix metalloproteinases and their inhibitors secreted by Ehrlich ascites tumor cells.
Neoplasms
Effects of matrix metalloproteinase inhibitor BB-94 on liver cancer growth and metastasis in a patient-like orthotopic model LCI-D20.
Neoplasms
Effects of nutrients on matrix metalloproteinases in human T-lymphotropic virus type 1 positive and negative malignant T-lymphocytes.
Neoplasms
Effects of rhaponticin on retinal oxidative stress and inflammation in diabetes through NRF2/HO-1/NF-?B signalling.
Neoplasms
Effects of RNA silencing of matrix metalloproteinase-2 on the growth of esophageal carcinoma cells in vivo.
Neoplasms
Effects of RNAi-mediated matrix metalloproteinase-2 gene silencing on the invasiveness and adhesion of esophageal carcinoma cells, KYSE150.
Neoplasms
Effects of sex steroids and growth factors on invasive activity and 5'-deoxy-5-fluorouridine sensitivity in ovarian adenocarcinoma OMC-3 cells.
Neoplasms
Effects of sex steroids and growth factors on migration and invasion of endometrial adenocarcinoma SNG-M cells in vitro.
Neoplasms
Effects of silibinin on cell growth and invasive properties of a human hepatocellular carcinoma cell line, HepG-2, through inhibition of extracellular signal-regulated kinase 1/2 phosphorylation.
Neoplasms
Effects of sulfasalazine and its metabolites on steady state messenger RNA concentrations for inflammatory cytokines, matrix metalloproteinases, and tissue inhibitors of metalloproteinase in rheumatoid synovial fibroblasts.
Neoplasms
Effects of synthetic peptides and protease inhibitors on the interaction of a human ovarian cancer cell line (NIH:OVCAR-3) with a reconstituted basement membrane (Matrigel).
Neoplasms
Effects of the Tight Junction Protein CLDN6 on Cell Migration and Invasion in High-Grade Meningioma.
Neoplasms
Effects of tumor necrosis factor-alpha and interferon-gamma on expressions of matrix metalloproteinase-2 and -9 in human bladder cancer cells.
Neoplasms
Efficacy Evaluation of Combination Treatment Using Gemcitabine and Radioimmunotherapy with 90Y-Labeled Fully Human Anti-CD147 Monoclonal Antibody 059-053 in a BxPC-3 Xenograft Mouse Model of Refractory Pancreatic Cancer.
Neoplasms
Efficacy of decitabine-loaded gelatinases-stimuli nanoparticles in overcoming cancer drug resistance is mediated via its enhanced demethylating activity to transcription factor AP-2 epsilon.
Neoplasms
EGCG attenuates pro-inflammatory cytokines and chemokines production in LPS-stimulated L02 hepatocyte.
Neoplasms
EGF promotes invasion by PANC-1 cells through Rac1/ROS-dependent secretion and activation of MMP-2.
Neoplasms
Elevated activities of MMP-2 in the non-tumorous lung tissues of curatively resected stage I NSCLC patients are associated with tumor recurrence and a poor survival.
Neoplasms
Elevated cell migration, invasion and tumorigenicity in human KB carcinoma cells transfected with COX-2 cDNA.
Neoplasms
Elevated concentrations of serum matrix metalloproteinase-2 and -9 and their associations with circulating markers of cardiovascular diseases in chronic arsenic-exposed individuals.
Neoplasms
Elevated expression levels of androgen receptors and matrix metalloproteinase-2 and -9 in 30 cases of hepatocellular carcinoma compared with adjacent tissues as predictors of cancer invasion and staging.
Neoplasms
Elevated levels of angiostatin in effusions from patients with malignant disease.
Neoplasms
Elevated levels of circulating plasma matrix metalloproteinase 9 in non-small cell lung cancer patients.
Neoplasms
Elevated levels of serum and plasma metalloproteinases in patients with gastric cancer.
Neoplasms
Elevated Serum and Cerebrospinal Fluid CD138 in Patients With Anti-N-Methyl-d-Aspartate Receptor Encephalitis.
Neoplasms
Elevated serum levels of human matrix metalloproteinase-9 (MMP-9) during the induction of peripheral blood stem cell mobilization by granulocyte colony-stimulating factor (G-CSF).
Neoplasms
Elevation of seprase expression and promotion of an invasive phenotype by collagenous matrices in ovarian tumor cells.
Neoplasms
EMMPRIN contributes to the in vitro invasion of human salivary adenoid cystic carcinoma cells.
Neoplasms
Emmprin in epithelioid sarcoma: expression in tumor cell membrane and stimulation of MMP-2 production in tumor-associated fibroblasts.
Neoplasms
EMMPRIN silencing inhibits proliferation and perineural invasion of human salivary adenoid cystic carcinoma cells in vitro and in vivo.
Neoplasms
Emmprin, released as a microvesicle in epithelioid sarcoma, interacts with fibroblasts.
Neoplasms
EMMPRIN-induced MMP-2 activation cascade in human cervical squamous cell carcinoma.
Neoplasms
Enamel matrix derivative induces the expression of tissue inhibitor of matrix metalloproteinase-3 in human gingival fibroblasts via extracellular signal-regulated kinase.
Neoplasms
Enantioselective Effects of o,p'-DDT on Cell Invasion and Adhesion of Breast Cancer Cells: Chirality in Cancer Development.
Neoplasms
Endometrial tumor invasiveness is related to metalloproteinase 2 and tissue inhibitor of metalloproteinase 2 expressions.
Neoplasms
Endostatin improves radioresponse and blocks tumor revascularization after radiation therapy for A431 xenografts in mice.
Neoplasms
Endothelial derived vasoactive factors and leukocyte derived inflammatory mediators in subjects with asymptomatic atherosclerosis.
Neoplasms
Endothelial TRPV4 channels prevent tumor growth and metastasis via modulation of tumor angiogenesis and vascular integrity.
Neoplasms
Endurance Training Depletes Antioxidant System but Does Not Affect Endothelial Functions in Women with Abdominal Obesity: A Randomized Trial with a Comparison to Endurance-Strength Training.
Neoplasms
Engineered peptides with enzymatically cleavable domains for controlling the release of model protein drug from "soft" nanoparticles.
Neoplasms
Enhanced cell surface expression of matrix metalloproteinases and their inhibitors, and tumor-induced host response in progression of human gastric carcinoma.
Neoplasms
Enhanced expression of tissue inhibitor of metalloproteinase-2 (TIMP-2) in the stroma of breast carcinomas correlates with tumor recurrence.
Neoplasms
Enhanced expression of tissue inhibitors of metalloproteinases in human colorectal tumors.
Neoplasms
Enhanced invasiveness of drug-resistant acute myeloid leukemia cells through increased expression of matrix metalloproteinase-2.
Neoplasms
Enhanced metastatic dissemination to multiple organs by melanoma and lymphoma cells in timp-3-/- mice.
Neoplasms
Enhanced production of matrix metalloproteinase-2 in human head and neck carcinomas is correlated with lymph node metastasis.
Neoplasms
Enhanced production of matrix metalloproteinases and activation of matrix metalloproteinase 2 (gelatinase A) in human gastric carcinomas.
Neoplasms
Enhanced urinary gelatinase activities (matrix metalloproteinases 2 and 9) are associated with early-stage bladder carcinoma: a comparison with clinically used tumor markers.
Neoplasms
Enhancement of membrane-type 1-matrix metalloproteinase (MT1-MMP) production and sequential activation of progelatinase A on human squamous carcinoma cells co-cultured with human dermal fibroblasts.
Neoplasms
Enhancement of radiotherapy efficacy by docetaxel-loaded gelatinase-stimuli PEG-Pep-PCL nanoparticles in gastric cancer.
Neoplasms
Enhancing Accumulation and Penetration of HPMA Copolymer-Doxorubicin Conjugates in 2D and 3D Prostate Cancer Cells via iRGD Conjugation with an MMP-2 Cleavable Spacer.
Neoplasms
Enhancing cancer targeting and anticancer activity by a stimulus-sensitive multifunctional polymer-drug conjugate.
Neoplasms
Enrichment of regulatory T cells in invasive breast tumor correlates with the upregulation of IL-17A expression and invasiveness of the tumor.
Neoplasms
Enzymatic activation of cell-penetrating peptides in self-assembled nanostructures triggers fibre-to-micelle morphological transition.
Neoplasms
Epidermal growth factor promotes invasiveness of pancreatic cancer cells through NF-kappaB-mediated proteinase productions.
Neoplasms
Epidermal growth factor receptor regulates MT1-MMP and MMP-2 synthesis in SiHa cells via both PI3-K/AKT and MAPK/ERK pathways.
Neoplasms
Epidermal growth factor receptor-mediated regulation of matrix metalloproteinase-2 and matrix metalloproteinase-9 in MCF-7 breast cancer cells.
Neoplasms
Epigallocatechin-3-gallate ameliorates LPS-induced inflammation by inhibiting the phosphorylation of Akt and ERK signaling molecules in rat H9c2 cells.
Neoplasms
Epigallocatechin-3-gallate inhibits doxorubicin-induced inflammation on human ovarian tissue.
Neoplasms
Epigallocatechin-3-Gallate: The Prospective Targeting of Cancer Stem Cells and Preventing Metastasis of Chemically-Induced Mammary Cancer in Rats.
Neoplasms
Epigenetic Control of the Invasion-promoting MT1-MMP/MMP-2/TIMP-2 Axis in Cancer Cells.
Neoplasms
Epigenetic inactivation of the tissue inhibitor of metalloproteinase-2 (TIMP-2) gene in human prostate tumors.
Neoplasms
Epigenetically induced changes in nuclear textural patterns and gelatinase expression in human fibrosarcoma cells.
Neoplasms
Epithelial expression of extracellular matrix metalloproteinase inducer/CD147 and matrix metalloproteinase-2 in neoplasms and precursor lesions derived from cutaneous squamous cells: An immunohistochemical study.
Neoplasms
Epithelial MMP-2 expression correlates with worse prognosis in pancreatic cancer.
Neoplasms
Equine sarcoid fibroblasts over-express matrix metalloproteinases and are invasive.
Neoplasms
ERM/ETV5 up-regulation plays a role during myometrial infiltration through matrix metalloproteinase-2 activation in endometrial cancer.
Neoplasms
Esophageal Cancer Development: Crucial Clues Arising from the Extracellular Matrix.
Neoplasms
Estradiol and tamoxifen regulate endostatin generation via matrix metalloproteinase activity in breast cancer in vivo.
Neoplasms
Estrogen promotes tumor metastasis via estrogen receptor beta-mediated regulation of matrix-metalloproteinase-2 in non-small cell lung cancer.
Neoplasms
Estrogen receptor subtype expression and regulation is altered in papillary thyroid cancer after menopause.
Neoplasms
Estrogenic and antiestrogenic regulation of MMP-2 and MMP-13 mRNA in RUCA-I endometrial tumor cells in vitro and in vivo.
Neoplasms
Ethanol-induced in vitro invasion of breast cancer cells: the contribution of MMP-2 by fibroblasts.
Neoplasms
Ethyl gallate suppresses proliferation and invasion in human breast cancer cells via Akt-NF-?B signaling.
Neoplasms
Euodia pasteuriana Methanol Extract Exerts Anti-Inflammatory Effects by Targeting TAK1 in the AP-1 Signaling Pathway.
Neoplasms
EVALUATING MMP-2 AND TGFß-RI EXPRESSION IN CIRCULATING TUMOR CELLS OF PANCREATIC CANCER PATIENTS AND THEIR CORRELATION WITH CLINICAL EVOLUTION.
Neoplasms
Evaluation of a Sesquiterpene as Possible Drug Lead Against Gelatinases via Molecular Dynamics Simulations.
Neoplasms
Evaluation of a triple-helical peptide with quenched FluorSophores for optical imaging of MMP-2 and MMP-9 proteolytic activity.
Neoplasms
Evaluation of basement membrane components and the 72 kDa type IV collagenase in serous tumors of the ovary.
Neoplasms
Evaluation of basement membrane degradation during TNF-alpha-induced increase in epithelial permeability.
Neoplasms
Evaluation of chemotherapy with nanosomal paclitaxel and gene therapy expressing apoptosis-inducing proteins in the management of spontaneous canine mammary neoplasm.
Neoplasms
Evaluation of EMMPRIN and MMP-2 in the prognosis of primary cutaneous malignant melanoma.
Neoplasms
Evaluation of hepatocellular carcinoma aggressiveness by a panel of extracellular matrix antigens.
Neoplasms
Evaluation of HIV RNA and markers of immune activation as predictors of HIV-associated dementia.
Neoplasms
Evaluation of invasiveness of astrocytoma using (1)H-magnetic resonance spectroscopy: correlation with expression of matrix metalloproteinase-2.
Neoplasms
Evaluation of matrix metalloproteinase 2 expression in cervical carcinogenesis using tissue array and integrated optical density for immunoreactivity.
Neoplasms
Evaluation of Matrix Metalloproteinase-2 (MMP-2) Activity with Film in situ Zymography for Improved Cytological Diagnosis of Breast Tumors.
Neoplasms
Evaluation of matrix metalloproteinase-2 and -9 in the cerebrospinal fluid of dogs with intracranial tumors.
Neoplasms
Evaluation of matrix metalloproteinases (MMP)-2 and MMP-9 activity in serum and biochemical and hematological parameters in spontaneous canine cutaneous tumors before and after surgical treatment.
Neoplasms
Evaluation of MMP-2, MMP-9, TIMP-1, TIMP-2, NGAL and MMP-9/NGAL complex in urine and sera from patients with bladder cancer.
Neoplasms
Evaluation of Suppressive Effects of Tranilast on the Invasion/Metastasis Mechanism in a Murine Pancreatic Cancer Cell Line.
Neoplasms
Evaluation of the Effect Derived from Silybin with Vitamin D and Vitamin E Administration on Clinical, Metabolic, Endothelial Dysfunction, Oxidative Stress Parameters, and Serological Worsening Markers in Nonalcoholic Fatty Liver Disease Patients.
Neoplasms
Evidence for tumor-host cooperation in regulating MMP-2 expression in human colon cancer.
Neoplasms
Evodiamine inhibits the migration and invasion of nasopharyngeal carcinoma cells in vitro via repressing MMP-2 expression.
Neoplasms
Ex-FABP: a fatty acid binding lipocalin developmentally regulated in chicken endochondral bone formation and myogenesis.
Neoplasms
Excessive inflammation portends complications: Wound cytokines and head and neck surgery outcomes.
Neoplasms
Excretion of matrix metalloproteinases 2 and 9 in urine is associated with a high stage and grade of bladder carcinoma.
Neoplasms
Exploring the action of RGDV-gemcitabine on tumor metastasis, tumor growth and possible action pathway.
Neoplasms
Exploring the prevalence of skin tears and skin properties related to skin tears in elderly patients at a long-term medical facility in Japan.
Neoplasms
Exposure of melanoma cells to dacarbazine results in enhanced tumor growth and metastasis in vivo.
Neoplasms
Expression analysis of three miRNAs, miR-26a, miR-29b and miR-519d, in relation to MMP-2 expression level in non-small cell lung cancer patients: a pilot study.
Neoplasms
Expression and activation of matrix metalloproteinase-2 (MMP-2) and its co-localization with membrane-type 1 matrix metalloproteinase (MT1-MMP) correlate with melanoma progression.
Neoplasms
Expression and activity of matrix metalloproteinases-2 and -9 in serum, core needle biopsies and tissue specimens of prostate cancer patients.
Neoplasms
Expression and clinical significance of HMGB1 in human liver cancer: Knockdown inhibits tumor growth and metastasis in vitro and in vivo.
Neoplasms
Expression and in-situ localization of genes coding for extracellular matrix proteins and extracellular matrix degrading proteases in pancreatic cancer.
Neoplasms
Expression and localization of 72 kDa type IV collagenase (MMP-2) in human malignant gliomas in vivo.
Neoplasms
Expression and prognostic impact of matrix metalloproteinase-2 (MMP-2) in astrocytomas.
Neoplasms
Expression and quantitative analysis of matrix metalloproteinase-2 and -9 in human gliomas.
Neoplasms
Expression and role of matrix metalloproteinases MMP-2 and MMP-9 in human spinal column tumors.
Neoplasms
Expression and serum levels of MMP-2 and MMP-9 during human melanoma progression.
Neoplasms
Expression and tissue localization of membrane-type 1, 2, and 3 matrix metalloproteinases in human astrocytic tumors.
Neoplasms
Expression levels of genes that regulate metastasis and angiogenesis correlate with advanced pathological stage of renal cell carcinoma.
Neoplasms
Expression of 72 kilodalton and 92 kilodalton type IV collagenase in malignant fibrous histiocytomas and dermatofibromas.
Neoplasms
Expression of 72 kilodalton type IV collagenase (gelatinase A) in benign and malignant ovarian tumors.
Neoplasms
Expression of 92-kDa type IV collagenase mRNA by eosinophils associated with basal cell carcinoma.
Neoplasms
Expression of adhesion factors and degrading proteins in primary and secondary glioblastomas and their precursor tumors.
Neoplasms
Expression of Alpha-Enolase (ENO1), Myc Promoter-Binding Protein-1 (MBP-1) and Matrix Metalloproteinases (MMP-2 and MMP-9) Reflect the Nature and Aggressiveness of Breast Tumors.
Neoplasms
Expression of bcl-2 correlates with poor prognosis and modulates migration of nasopharyngeal carcinoma cells.
Neoplasms
Expression of CD44 and MMP-2: possible association with histopathological features of pleuro-pulmonary solitary fibrous tumors.
Neoplasms
Expression of CD44v3 splice variant is associated with the visceral metastatic phenotype of human melanoma.
Neoplasms
Expression of collagenase IV (basement membrane collagenase) activity in murine tumor cell hybrids that differ in metastatic potential.
Neoplasms
Expression of collagenase-3 (matrix metalloproteinase-13) in human gastric cancer.
Neoplasms
Expression of collagenases-1 and -3 and their inhibitors TIMP-1 and -3 correlates with the level of invasion in malignant melanomas.
Neoplasms
Expression of CXCR4 and MMP-2 is associated with poor prognosis in patients with osteosarcoma.
Neoplasms
Expression of cyclooxygenase-2 in colorectal cancer and its clinical significance.
Neoplasms
Expression of cyclooxygenase-2 in renal cell carcinoma: correlation with tumor cell proliferation, apoptosis, angiogenesis, expression of matrix metalloproteinase-2, and survival.
Neoplasms
Expression of cyclooxygenase-2, vascular endothelial growth factor and matrix metalloproteinase-2 in patients with primary laryngeal carcinoma: a tissue microarray study.
Neoplasms
Expression of cytokeratin 19 and matrix metalloproteinase 2 predicts lymph node metastasis in hepatocellular carcinoma.
Neoplasms
Expression of DCUN1D1 in laryngeal squamous cell carcinoma and its inhibiting effect on TU-177 cells after interfered by RNA.
Neoplasms
Expression of decorin in esophageal cancer in relation to the expression of three isoforms of transforming growth factor-beta (TGF-beta1, -beta2, and -beta3) and matrix metalloproteinase-2 activity.
Neoplasms
Expression of Discoidin Domain Receptor 2 (DDR2) Extracellular Domain in Pichia Pastoris and Functional Analysis in Synovial Fibroblasts and NIT3T3 Cells.
Neoplasms
Expression of E-cadherin, beta-catenin, cathepsin D, gelatinases and their inhibitors in invasive ductal breast carcinomas.
Neoplasms
Expression of E1AF, an ets-oncogene transcription factor, highly correlates with malignant phenotype of malignant melanoma through up-regulation of the membrane-type-1 matrix metalloproteinase gene.
Neoplasms
Expression of emmprin and matrix metalloproteinases (MMPs) in peripheral nerve sheath tumors: emmprin and membrane-type (MT)1-MMP expressions are associated with malignant potential.
Neoplasms
Expression of EMMPRIN in adenoid cystic carcinoma of salivary glands: correlation with tumor progression and patients' prognosis.
Neoplasms
Expression of extracellular matrix-degrading proteins in classic, atypical, and anaplastic meningiomas.
Neoplasms
Expression of Fhit, cell adhesion molecules and matrix metalloproteinases in atypical adenomatous hyperplasia and pulmonary adenocarcinoma.
Neoplasms
Expression of FLJ10540 is correlated with aggressiveness of oral cavity squamous cell carcinoma by stimulating cell migration and invasion through increased FOXM1 and MMP-2 activity.
Neoplasms
Expression of gelatinase (MMP-2 and MMP-9) and cyclooxygenase-2 (COX-2) in endometrial carcinoma.
Neoplasms
Expression of gelatinase A and TIMP-2 mRNAs in desmoplastic fibroblasts in both mammary carcinomas and basal cell carcinomas of the skin.
Neoplasms
Expression of gelatinase A, tissue inhibitor of metalloproteinases-2, matrilysin, and trypsin(ogen) in lung neoplasms: an immunohistochemical study.
Neoplasms
Expression of gelatinase-A (MMP-2) in human colon cancer and normal colon mucosa.
Neoplasms
Expression of gelatinase/type IV collagenase in tumor necrosis correlates with cell detachment and tumor invasion.
Neoplasms
Expression of genes encoding type IV collagen-degrading metalloproteinases and tissue inhibitors of metalloproteinases in various human tumor cells.
Neoplasms
Expression of genes in the canine pre-implantation uterus and embryo: implications for an active role of the embryo before and during invasion.
Neoplasms
Expression of hepatocyte growth factor and matrix metalloproteinase-2 in human glioma.
Neoplasms
Expression of hypoxia-inducible factor-1?, vascular endothelial growth factor and matrix metalloproteinase-2 in sacral chordomas.
Neoplasms
Expression of immunoreactive matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases in human normal livers and primary liver tumors.
Neoplasms
Expression of integrin alphaVbeta3 in pancreatic carcinoma: relation to MMP-2 activation and lymph node metastasis.
Neoplasms
Expression of interleukin-8 by human melanoma cells up-regulates MMP-2 activity and increases tumor growth and metastasis.
Neoplasms
Expression of laminin, collagen IV, fibronectin, and type IV collagenase in gastric carcinoma. An immunohistochemical study of 87 patients.
Neoplasms
Expression of latent matrix metalloproteinase 9 (MMP-9) predicts survival in advanced ovarian cancer.
Neoplasms
Expression of LGR8 and related biomarkers in hepatocellular carcinoma: correlation with clinicopathological parameters.
Neoplasms
Expression of matrix metalloprotease-2 (MMP-2) and the activator membrane type 1 (MT1-MMP) in canine mammary carcinomas.
Neoplasms
Expression of matrix metalloprotease-9 in vascular pericytes in human breast cancer.
Neoplasms
Expression of matrix metalloproteinase (gelatinase) in T1 adenocarcinoma of the lung.
Neoplasms
Expression of matrix metalloproteinase 1, matrix metalloproteinase 2, and matrix metalloproteinase 9 in carcinoma of the head and neck.
Neoplasms
Expression of matrix metalloproteinase 2 (MMP-2) and tissue inhibitor of metalloproteinase 2 (TIMP-2) in medullary thyroid carcinoma: prognostic implications.
Neoplasms
Expression of matrix metalloproteinase 2 (MMP-2), E-cadherin and Ki-67 in metastatic and non-metastatic canine mammary carcinomas.
Neoplasms
Expression of matrix metalloproteinase 2 and 9 in breast cancer and breast fibroadenoma: a randomized, double-blind study.
Neoplasms
Expression of Matrix Metalloproteinase 2 and Extracellular Matrix Metalloproteinase Inducer are Unfavorable Postoperative Prognostic Factors in Intrahepatic Cholangiocarcinoma.
Neoplasms
Expression of matrix metalloproteinase 2 and its tissue inhibitor in oral squamous cell carcinoma.
Neoplasms
Expression of matrix metalloproteinase 9 (MMP-9/gelatinase B) in adenocarcinomas strongly correlated with expression of immune response genes.
Neoplasms
Expression of matrix metalloproteinase gelatinase A messenger ribonucleic acid in parathyroid carcinomas.
Neoplasms
Expression of matrix metalloproteinase-1, -2 and -3 in squamous cell carcinoma and actinic keratosis.
Neoplasms
Expression of matrix metalloproteinase-2 (MMP-2) and of membrane-type-1-matrix metalloproteinase (MT1-MMP) in transitional cell carcinoma of the upper urinary tract.
Neoplasms
Expression of matrix metalloproteinase-2 (mmp-2) in cervical neoplasia - immunohistochemical and in-situ hybridization studies.
Neoplasms
Expression of matrix metalloproteinase-2 and -9 and membrane-type 1 matrix metalloproteinase in melanocytic tumors of dogs and canine melanoma cell lines.
Neoplasms
Expression of matrix metalloproteinase-2 and -9 and their inhibitors, tissue inhibitor of metalloproteinase-1 and -2, in primary cultures of human prostatic stromal and epithelial cells.
Neoplasms
Expression of matrix metalloproteinase-2 and -9 in human ligamentum flavum cells treated with tumor necrosis factor-? and interleukin-1?.
Neoplasms
Expression of matrix metalloproteinase-2 and 9 in cervical intraepithelial neoplasia and cervical carcinoma among different age groups of premenopausal and postmenopausal women.
Neoplasms
Expression of matrix metalloproteinase-2 and its tissue inhibitor-2 in fetal and neoplastic thyroid tissue and their significance as diagnostic and prognostic markers in papillary carcinoma.
Neoplasms
Expression of matrix metalloproteinase-2 and survivin in endometrioid and nonendometrioid endometrial cancers and clinicopathologic significance.
Neoplasms
Expression of matrix metalloproteinase-2 in glial and neuronal tumor cell lines: inverse correlation with proliferation rate.
Neoplasms
Expression of matrix metalloproteinase-2 in preinvasive and invasive carcinoma of the uterine cervix.
Neoplasms
Expression of matrix metalloproteinase-2 in serous borderline ovarian tumors is associated with noninvasive implant formation.
Neoplasms
Expression of matrix metalloproteinase-2 related to lymph node metastasis of oral squamous cell carcinoma. A clinicopathologic study.
Neoplasms
Expression of Matrix Metalloproteinase-2, but not Caspase-3, Facilitates Distinction between Benign and Malignant Thyroid Follicular Neoplasms.
Neoplasms
Expression of matrix metalloproteinases (MMP-2 and -9) and their inhibitors (TIMP-1 and -2) in prostate cancer tissue.
Neoplasms
Expression of matrix metalloproteinases (MMP-2, MMP-9, MT1-MMP) and their inhibitors (TIMP-1, TIMP-2) in common epithelial tumors of the ovary.
Neoplasms
Expression of matrix metalloproteinases (MMPs) in cultured hepatocellular carcinoma (HCC) cells and surgically resected HCC tissues.
Neoplasms
Expression of matrix metalloproteinases (MMPs-2, -7, -9, and -26) and tissue inhibitors of metalloproteinases (TIMPs-1 and -2) in pleomorphic adenomas and adenoid cystic carcinomas.
Neoplasms
Expression of matrix metalloproteinases 2 and 7 in tumor cells correlates with the World Health Organization classification subtype and clinical stage of thymic epithelial tumors.
Neoplasms
Expression of matrix metalloproteinases 2 and 9 in human gastric cancer and superficial gastritis.
Neoplasms
Expression of matrix metalloproteinases 2 and 9 in meningiomas associated with different degrees of brain invasiveness and edema.
Neoplasms
Expression of matrix metalloproteinases 2, 7 and 9 in patients with colorectal cancer.
Neoplasms
Expression of Matrix Metalloproteinases and Its Inhibitor in Gastric Adenocarcinoma.
Neoplasms
Expression of matrix metalloproteinases and their inhibitors correlates with invasion and metastasis in squamous cell carcinoma of the head and neck.
Neoplasms
Expression of matrix metalloproteinases and their inhibitors in human brain tumors.
Neoplasms
Expression of matrix metalloproteinases and their inhibitors in human bronchopulmonary carcinomas: quantificative and morphological analyses.
Neoplasms
Expression of matrix metalloproteinases and their inhibitors in medulloblastomas and their prognostic relevance.
Neoplasms
Expression of matrix metalloproteinases and tissue inhibitor of matrix metalloproteinases in non-small-cell lung cancer.
Neoplasms
Expression of matrix metalloproteinases and tissue inhibitor of metalloproteinases in head and neck squamous cell carcinoma.
Neoplasms
Expression of matrix metalloproteinases and tissue inhibitor of metalloproteinases in laryngeal and pharyngeal squamous cell carcinoma: A quantitative analysis.
Neoplasms
Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinase in uterine endometrial carcinoma and a correlation between expression of matrix metalloproteinase-7 and prognosis.
Neoplasms
Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human chondrosarcomas.
Neoplasms
Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human pancreatic adenocarcinomas: clinicopathologic and prognostic significance of matrilysin expression.
Neoplasms
Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in reactive and neoplastic lymphoid cells.
Neoplasms
Expression of matrix metalloproteinases in benign and malignant follicular thyroid lesions.
Neoplasms
Expression of matrix metalloproteinases in gallbladder carcinoma and their significance in carcinogenesis.
Neoplasms
Expression of matrix metalloproteinases in human transitional cell carcinoma of the urinary bladder.
Neoplasms
Expression of matrix metalloproteinases in patients with uterine smooth muscle tumors: an immunohistochemical analysis of MMP-1 and MMP-2 protein expression in leiomyoma, uterine smooth muscle tumor of uncertain malignant potential, and leiomyosarcoma.
Neoplasms
Expression of matrix metalloproteinases in supraglottic carcinoma and its clinical implication for estimating lymph node metastases.
Neoplasms
Expression of matrix metalloproteinases in the microenvironment of spontaneous and experimental melanoma metastases reflects the requirements for tumor formation.
Neoplasms
Expression of matrix metalloproteinases MMP-2 and MMP-9 in gastric cancer and their relation to claudin-4 expression.
Neoplasms
Expression of matrix metalloproteinases MMP-2, MMP-9 and their tissue inhibitors TIMP-1, -2, and -3 in benign and malignant tumours of the salivary gland.
Neoplasms
Expression of matrix metalloproteinases, cytokines, and connexins in diabetic and nondiabetic human keratinocytes before and after transplantation into an ex vivo wound-healing model.
Neoplasms
Expression of matrix metalloproteinases, their inhibitors, and urokinase plasminogen activator in human meningiomas.
Neoplasms
Expression of matrix metalloproteinases, tissue inhibitors of metalloproteinase, collagens, and Ki67 antigen in pleural malignant mesothelioma: an immunohistochemical and electron microscopic study.
Neoplasms
Expression of matrix metalloproteinases-1, -2, and -9; tissue inhibitors of matrix metalloproteinases-1 and -2; cathepsin B; urokinase plasminogen activator; and plasminogen activator inhibitor, type I in skull base chordoma.
Neoplasms
Expression of matrix metalloproteinases-2 and -9 by cells isolated from the peritoneal fluid of women with ovarian carcinoma.
Neoplasms
Expression of Matrix Metalloproteinases-2/-9 is Associated With Microvessel Density in Pancreatic Cancer.
Neoplasms
Expression of membrane type 1 matrix metalloproteinase (MMP-14) in epithelial ovarian cancer: high level expression in clear cell carcinoma.
Neoplasms
Expression of membrane type 1 matrix metalloproteinase (MT1-MMP) in A2058 melanoma cells is associated with MMP-2 activation and increased tumor growth and vascularization.
Neoplasms
Expression of membrane type 1 matrix metalloproteinase, matrix metalloproteinase 2 and tissue inhibitor of metalloproteinase 2 in human cartilaginous tumors with special emphasis on mesenchymal and dedifferentiated chondrosarcoma.
Neoplasms
Expression of membrane-anchored matrix metalloproteinase inhibitor reversion inducing cysteine rich protein with Kazal motifs in murine cell lines.
Neoplasms
Expression of membrane-type matrix metalloproteinase in rabbit neointimal tissue and its correlation with matrix-metalloproteinase-2 activation.
Neoplasms
Expression of metalloproteinase 2 and 9 and their inhibitors in renal cell carcinoma.
Neoplasms
Expression of metalloproteinase-2, metalloproteinase-9, and tissue inhibitor of metalloproteinase-1 in transitional cell carcinoma of upper urinary tract: correlation with tumor stage and survival.
Neoplasms
Expression of metalloproteinases and their inhibitors in adenocarcinoma of the uterine cervix.
Neoplasms
Expression of metalloproteinases and tissue inhibitors of metalloproteinases in human osteoblast-like cells: differentiation is associated with repression of metalloproteinase biosynthesis.
Neoplasms
Expression of metalloproteinases endometrial stromal sarcoma: immunohistochemical study using image analysis.
Neoplasms
Expression of metalloproteinases MMP-2 and MMP-9 in sentinel lymph node and serum of patients with metastatic and non-metastatic breast cancer.
Neoplasms
Expression of metalloproteinases MMP-2 and MMP-9 is associated to the presence of androgen receptor in epithelial ovarian tumors.
Neoplasms
Expression of MMP-2 and -9 in short-term cultures of meningioma: influence of histological subtype.
Neoplasms
Expression of MMP-2 and MMP-9 in Benign Canine Rostrotentorial Meningiomas Is Not Correlated to the Extent of Peritumoral Edema.
Neoplasms
Expression of MMP-2 and MMP-9, their inhibitors, and the activator MT1-MMP in primary breast carcinomas.
Neoplasms
Expression of MMP-2 and TIMP-3 with incidence and prognosis of giant-cell tumor of the bone.
Neoplasms
Expression of MMP-2 correlates with increased angiogenesis in CNS metastasis of lung carcinoma.
Neoplasms
Expression of MMP-2 is associated with progression and lymph node metastasis of gastric carcinoma.
Neoplasms
Expression of MMP-2, MMP-7, MMP-9, MMP-10 and MMP-11 in human astrocytic and oligodendroglial gliomas.
Neoplasms
Expression of MMP-2, MMP-9, and urokinase-type plasminogen activator in cervical intraepithelial neoplasia.
Neoplasms
Expression of MMP-2,TIMP-2 protein and the ratio of MMP-2/TIMP-2 in gallbladder carcinoma and their significance.
Neoplasms
Expression of MMPs and TIMPs in human pterygia and cultured pterygium epithelial cells.
Neoplasms
Expression of most matrix metalloproteinase family members in breast cancer represents a tumor-induced host response.
Neoplasms
Expression of mRNA for gelatinase A and TIMP-2 in cell cultures and tissue samples derived from breast and lung carcinomas.
Neoplasms
Expression of nm23, MMP-2, TIMP-2 in breast neoplasm in Zhengzhou Center Hospital, China.
Neoplasms
Expression of nm23-H1 gene product in sarcomatous cancer cells of renal cell carcinoma: correlation with tumor stage and expression of matrix metalloproteinase-2, matrix metalloproteinase-9, sialyl Lewis X, and c-erbB-2.
Neoplasms
Expression of peroxisome proliferator-activated receptor g, E-cadherin and matrix metalloproteinases-2 in gastric carcinoma and lymph node metastases.
Neoplasms
Expression of receptor for advanced glycation end products (RAGE) and MMP-9 in human pancreatic cancer cells.
Neoplasms
Expression of RECK and MMP-2 in salivary adenoid cystic carcinoma: Correlation with tumor progression and patient prognosis.
Neoplasms
Expression of the active form of MMP-2 on the surface of leukemic cells accounts for their in vitro invasion.
Neoplasms
Expression of the extracellular matrix metalloproteinase inducer (EMMPRIN) and the matrix metalloproteinase-2 in bronchopulmonary and breast lesions.
Neoplasms
Expression of the miR200 family of microRNAs in mesothelial cells suppresses the dissemination of ovarian cancer cells.
Neoplasms
Expression of tissue inhibitor of matrix metalloproteinase-2 correlates with activation of matrix metalloproteinase-2 and predicts poor prognosis in tongue squamous cell carcinoma.
Neoplasms
Expression of tissue inhibitor of metalloproteinase-1 and type IV collagenase/gelatinase messenger RNAs in human breast cancer.
Neoplasms
Expression of tissue inhibitor of metalloproteinase-3 (TIMP-3) and its prognostic significance in resected non-small cell lung cancer.
Neoplasms
Expression of tissue inhibitor of metalloproteinase-3 by transplanted VSMCs modifies heart structure and function after myocardial infarction.
Neoplasms
Expression of tissue inhibitor of metalloproteinases TIMP-2 in human colorectal cancer--a predictor of tumour stage.
Neoplasms
Expression of tissue levels of matrix metalloproteinases and their inhibitors in breast cancer.
Neoplasms
Expression of tissue levels of matrix metalloproteinases and tissue inhibitors of metalloproteinases in gastric adenocarcinoma.
Neoplasms
Expression of tissue levels of matrix metalloproteinases and tissue inhibitors of metalloproteinases in renal cell carcinoma.
Neoplasms
Expression of type IV collagen and its degrading enzymes in squamous cell carcinoma of lung.
Neoplasms
Expression of type IV collagenase and procollagen genes and its correlation with the tumorigenic, invasive, and metastatic abilities of oncogene-transformed human bronchial epithelial cells.
Neoplasms
Expression of type IV collagenase correlates with the expression of vascular endothelial growth factor in primary non-small cell lung cancer.
Neoplasms
Expression of WTH3 in breast cancer tissue and the effects on the biological behavior of breast cancer cells.
Neoplasms
Expression patterns of seprase, a membrane serine protease, in cervical carcinoma and cervical intraepithelial neoplasm.
Neoplasms
Expression patterns of stromal MMP-2 and tumoural MMP-2 and -9 are significant prognostic factors in invasive ductal carcinoma of the breast.
Neoplasms
Expression profile of epithelial-mesenchymal transition markers in non-muscle-invasive urothelial carcinoma of the bladder: correlation with intravesical recurrence following transurethral resection.
Neoplasms
Expression profiling using a cDNA array and immunohistochemistry for the extracellular matrix genes FN-1, ITGA-3, ITGB-5, MMP-2, and MMP-9 in colorectal carcinoma progression and dissemination.
Neoplasms
Expression variations and clinical significance of MMP-1, MMP-2 and inflammatory factors in serum of patients with deep venous thrombosis of lower extremity.
Neoplasms
Expression, association with clinicopathological features and prognostic potential of CEP55, p-Akt, FoxM1 and MMP-2 in astrocytoma.
Neoplasms
Expression, purification, refolding and in vitro recovery of active full length recombinant human gelatinase MMP-9 in Escherichia coli.
Neoplasms
Expressions of CD147, MMP-2 and MMP-9 in Laryngeal Carcinoma and its Correlation with Poor Prognosis.
Neoplasms
Expressions of matrix metalloproteinase-9 (MMP-9), dentin sialophosphoprotein (DSPP), and osteopontin (OPN) at histologically negative surgical margins may predict recurrence of oral squamous cell carcinoma.
Neoplasms
Expressions of Matrix Metalloproteinases 2, 7, and 9 in Carcinogenesis of Pancreatic Ductal Adenocarcinoma.
Neoplasms
Expressions of matrix metalloproteinases in early-stage oral squamous cell carcinoma as predictive indicators for tumor metastases and prognosis.
Neoplasms
Expressions of MMP-2, MMP-9 and VEGF are closely linked to growth, invasion, metastasis and angiogenesis of gastric carcinoma.
Neoplasms
Extracellular binding of indinavir to matrix metalloproteinase-2 and the alpha-7-nicotinic acetylcholine receptor: implications for use in cancer treatment.
Neoplasms
Extracellular heat shock protein (Hsp)70 and Hsp90? assist in matrix metalloproteinase-2 activation and breast cancer cell migration and invasion.
Neoplasms
Extracellular Matrix Component Shelled Nanoparticles as Dual Enzyme-Responsive Drug Delivery Vehicles for Cancer Therapy.
Neoplasms
Extracellular matrix expression in metastasizing and nonmetastasizing adenocarcinomas of the lung.
Neoplasms
Extracellular matrix metalloproteinase inducer and matrix metalloproteinase-2 overexpression is associated with loss of hormone receptor expression and poor prognosis in endometrial cancer.
Neoplasms
Extracellular Phosphorylation of TIMP-2 by Secreted c-Src Tyrosine Kinase Controls MMP-2 Activity.
Neoplasms
Extracellular protease mRNAs are predominantly expressed in the stromal areas of microdissected mouse breast carcinomas.
Neoplasms
Fabrication of In Vitro Cancer Microtissue Array on Fibroblast-Layered Nanofibrous Membrane by Inkjet Printing.
Neoplasms
FAK signaling in neoplastic disorders: a linkage between inflammation and cancer.
Neoplasms
Fibroblast activation protein ? in tumor microenvironment: Recent progression and implications (Review).
Neoplasms
Fibroblast Enhancement of Tumor Invasion in a Tumor-Host Interface Recapitulated in-vitro.
Neoplasms
Fibroblast remodeling of adsorbed collagen type IV is altered in contact with cancer cells.
Neoplasms
Fibroblasts and extracellular matrix differently modulate MMP activation by primary and metastatic head and neck cancer cells.
Neoplasms
Fibrotic injury after experimental deep vein thrombosis is determined by the mechanism of thrombogenesis.
Neoplasms
Fine Particulate Matter (PM2.5) Promoted the Invasion of Lung Cancer Cells via an ARNT2/PP2A/STAT3/MMP2 Pathway.
Neoplasms
Fisetin inhibits various attributes of angiogenesis in vitro and in vivo--implications for angioprevention.
Neoplasms
Fisetin, a dietary flavonoid, augments the anti-invasive and anti-metastatic potential of sorafenib in melanoma.
Neoplasms
Flubendazole elicits anti-metastatic effects in triple-negative breast cancer via STAT3 inhibition.
Neoplasms
Fluorogenic Disassembly of Self-Quenched Near-Infrared Nanoparticles Enables Matrix Metalloproteinase Detection.
Neoplasms
Focal adhesion kinase activation is required for TNF-?-induced production of matrix metalloproteinase-2 and proinflammatory cytokines in cultured human periodontal ligament fibroblasts.
Neoplasms
Focal localization of inflammatory cytokines and neurotrophins in a tongue chronic injury model.
Neoplasms
Folate-decorated arginine-based poly(ester urea urethane) nanoparticles as carriers for gambogic acid and effect on cancer cells.
Neoplasms
FoxM1 regulates transcription of JNK1 to promote the G1/S transition and tumor cell invasiveness.
Neoplasms
Fragile Gene WWOX Guides TFAP2A/TFAP2C-Dependent Actions Against Tumor Progression in Grade II Bladder Cancer.
Neoplasms
Fragment-Based Discovery of 5-Arylisatin-Based Inhibitors of Matrix Metalloproteinases 2 and 13.
Neoplasms
Fucoidan ameliorates steatohepatitis and insulin resistance by suppressing oxidative stress and inflammatory cytokines in experimental non-alcoholic fatty liver disease.
Neoplasms
Fully human anti-interleukin 8 antibody inhibits tumor growth in orthotopic bladder cancer xenografts via down-regulation of matrix metalloproteases and nuclear factor-kappaB.
Neoplasms
Fully human antibodies to MCAM/MUC18 inhibit tumor growth and metastasis of human melanoma.
Neoplasms
Fully humanized neutralizing antibodies to interleukin-8 (ABX-IL8) inhibit angiogenesis, tumor growth, and metastasis of human melanoma.
Neoplasms
Function of alpha3beta1-tetraspanin protein complexes in tumor cell invasion. Evidence for the role of the complexes in production of matrix metalloproteinase 2 (MMP-2).
Neoplasms
Functional activation of integrin alpha V beta 3 in tumor cells expressing membrane-type 1 matrix metalloproteinase.
Neoplasms
Functional analysis of matrix metalloproteinases and tissue inhibitors of metalloproteinases differentially expressed by variants of human HT-1080 fibrosarcoma exhibiting high and low levels of intravasation and metastasis.
Neoplasms
Functional and clinical evidence for NDRG2 as a candidate suppressor of liver cancer metastasis.
Neoplasms
Functional cooperativity by direct interaction between PAK4 and MMP-2 in the regulation of anoikis resistance, migration and invasion in glioma.
Neoplasms
Functional haplotypes in the promoter of matrix metalloproteinase-2 and lung cancer susceptibility.
Neoplasms
Functional haplotypes in the promoter of matrix metalloproteinase-2 predict risk of the occurrence and metastasis of esophageal cancer.
Neoplasms
Functional mimetic peptide discovery isolated by phage display interacts selectively to fibronectin domain and inhibits gelatinase.
Neoplasms
Functional vinorelbine plus schisandrin B liposomes destroying tumor metastasis in treatment of gastric cancer.
Neoplasms
Fusion expression of DDR2 extracellular domain in insect cells and its purification and function characterization.
Neoplasms
Fuzheng Huayu Formula () prevents rat renal interstitial fibrosis induced by HgCl2 via antioxidative stress and down-regulation of nuclear factor-kappa B activity.
Neoplasms
Galectin-1-mediated tumor invasion and metastasis, up-regulated matrix metalloproteinase expression, and reorganized actin cytoskeletons.
Neoplasms
Galloyl cyclic-imide derivative CH1104I inhibits tumor invasion through suppressing matrix metalloproteinase activity.
Neoplasms
Gamabufotalin suppressed osteosarcoma stem cells through the TGF-?/periostin/PI3K/AKT pathway.
Neoplasms
Gamma Radiation-Attenuated Toxoplasma gondii Provokes Apoptosis in Ehrlich Ascites Carcinoma-Bearing Mice Generating Long-Lasting Immunity.
Neoplasms
Gamma-irradiation induces matrix metalloproteinase II expression in a p53-dependent manner.
Neoplasms
Ganoderic acid T inhibits tumor invasion in vitro and in vivo through inhibition of MMP expression.
Neoplasms
Gelatin zymography and substrate cleavage assays of matrix metalloproteinase-2 in breast carcinoma cells overexpressing membrane type-1 matrix metalloproteinase.
Neoplasms
Gelatinase A (MMP-2) and its mRNA detected in both neoplastic and stromal cells of tumors with different invasive and metastatic properties.
Neoplasms
Gelatinase A activation is regulated by the organization of the polymerized actin cytoskeleton.
Neoplasms
Gelatinase A and membrane-type 1 matrix metalloproteinase mRNA: expressed in adrenocortical cancers but not in adenomas.
Neoplasms
Gelatinase A expression and localization in human breast cancers. An in situ hybridization study and immunohistochemical detection using confocal microscopy.
Neoplasms
Gelatinase A, membrane type 1 matrix metalloproteinase, and extracellular matrix metalloproteinase inducer mRNA expression: correlation with invasive growth of breast cancer.
Neoplasms
Gelatinase A-immunoreactive protein in ovarian lesions- prognostic value in epithelial ovarian cancer.
Neoplasms
Gelatinase A/TIMP-2 imbalance in lymph-node-positive breast carcinomas, as measured by RT-PCR.
Neoplasms
Gelatinase activity of matrix metalloproteinases during first-line chemotherapy in lung adenocarcinoma patients: an initial approach.
Neoplasms
Gelatinase concentrations and zymographic profiles in human breast cancer: matrix metalloproteinases circulating in plasma are better markers for the subclassification and early prediction of cancer: the coagulation/fibrinolysis pathways alter the release, activation and recovery of different gelatinases in serum.
Neoplasms
Gelatinase expression in Retinoblastoma: Modulation of LHBETATAG retinal tumor development by Anecortave Acetate.
Neoplasms
Gelatinase-stimuli strategy enhances the tumor delivery and therapeutic efficacy of docetaxel-loaded poly(ethylene glycol)-poly(?-caprolactone) nanoparticles.
Neoplasms
Gelatinases A and B (MMP-2 and MMP-9) in endometrial cancer-MMP-9 correlates to the grade and the stage.
Neoplasms
Gelatinases and their inhibitors in tumor metastasis: from biological research to medical applications.
Neoplasms
Gelatinolytic activities (matrix metalloproteinase-2 and -9) and soluble extracellular domain of Her-2/neu in pleural effusions.
Neoplasms
Gelatinolytic activity of matrix metalloproteinase in tumor tissues correlates with the invasiveness of oral cancer.
Neoplasms
Gelatinolytic activity of matrix metalloproteinase-2 and matrix metalloproteinase-9 in rat brain after implantation of 9L rat glioma cells.
Neoplasms
Gene Expression of Matrix Metalloproteinases and their Inhibitors (TIMPs) in Meningiomas of Dogs.
Neoplasms
Gene polymorphisms in odontogenic keratocysts and ameloblastomas: A systematic review.
Neoplasms
General protease and collagenase (IV) activity in C6 astrocytoma cells, C6 spheroids and implanted C6 spheroids.
Neoplasms
Generation and antitumor effects of an engineered and energized fusion protein VL-LDP-AE composed of single-domain antibody and lidamycin.
Neoplasms
Generation of antitumor peptides by connection of matrix metalloproteinase-9 peptide inhibitor to an endostatin fragment.
Neoplasms
Genes of laminin B1 chain, alpha 1 (IV) chain of type IV collagen, and 72-kd type IV collagenase are mainly expressed by the stromal cells of lung carcinomas.
Neoplasms
Genetic Deletion of Galectin-3 Alters the Temporal Evolution of Macrophage Infiltration and Healing Affecting the Cardiac Remodeling and Function after Myocardial Infarction in Mice.
Neoplasms
Genetic Predisposition of Polymorphisms in HMGB1-Related Genes to Breast Cancer Prognosis in Korean Women.
Neoplasms
Genistein reinforces the inhibitory effect of Cisplatin on liver cancer recurrence and metastasis after curative hepatectomy.
Neoplasms
GHGKHKNK Octapeptide (P-5m) Inhibits Metastasis of HCCLM3 Cell Lines via Regulation of MMP-2 Expression in in Vitro and in Vivo Studies.
Neoplasms
GHRH antagonist inhibits focal adhesion kinase (FAK) and decreases expression of vascular endothelial growth factor (VEGF) in human lung cancer cells in vitro.
Neoplasms
Ginsenoside Rg3 inhibition of vasculogenic mimicry in pancreatic cancer through downregulation of VE?cadherin/EphA2/MMP9/MMP2 expression.
Neoplasms
Glioma invasion in vitro: regulation by matrix metalloprotease-2 and protein kinase C.
Neoplasms
Glioma-astrocyte interaction modifies the astrocyte phenotype in a co-culture experimental model.
Neoplasms
Gluten exacerbates atherosclerotic plaque formation in ApoE-/- mice with diet-induced obesity.
Neoplasms
Gonadotropin-releasing hormone-II increases membrane type I metalloproteinase production via beta-catenin signaling in ovarian cancer cells.
Neoplasms
Granulocyte colony-stimulating factor (G-CSF)-mediated signaling regulates type IV collagenase activity in head and neck cancer cells.
Neoplasms
Grape seed extract suppresses MDA-MB231 breast cancer cell migration and invasion.
Neoplasms
Growth factor stimulation of matrix metalloproteinase expression and myoblast migration and invasion in vitro.
Neoplasms
Growth inhibition and regression of lung tumors by silibinin: modulation of angiogenesis by macrophage-associated cytokines and nuclear factor-kappaB and signal transducers and activators of transcription 3.
Neoplasms
Growth pattern correlates with the distribution of basement membrane and prognosis in lung adenocarcinoma.
Neoplasms
Guanylyl cyclase C prevents colon cancer metastasis by regulating tumor epithelial cell matrix metalloproteinase-9.
Neoplasms
Gypenosides inhibits migration and invasion of human oral cancer SAS cells through the inhibition of matrix metalloproteinase-2/ -9 and urokinase-plasminogen by ERK1/2 and NF-kappa B signaling pathways.
Neoplasms
H-ras oncogene-transformed human bronchial epithelial cells (TBE-1) secrete a single metalloprotease capable of degrading basement membrane collagen.
Neoplasms
Halofuginone inhibits phosphorylation of SMAD-2 reducing angiogenesis and leukemia burden in an acute promyelocytic leukemia mouse model.
Neoplasms
Halofuginone suppresses the lung metastasis of chemically induced hepatocellular carcinoma in rats through MMP inhibition.
Neoplasms
HDAC inhibitor trichostatin A suppresses esophageal squamous cell carcinoma metastasis through HADC2 reduced MMP-2/9.
Neoplasms
Heat shock protein 27 regulates human prostate cancer cell motility and metastatic progression.
Neoplasms
Heat shock-mediated transient increase in intracellular 3',5'-cyclic AMP results in tumor specific suppression of membrane type 1-matrix metalloproteinase production and progelatinase A activation.
Neoplasms
Heme oxygenase-1 expression is associated with tumor aggressiveness and outcomes in patients with bladder cancer: a correlation with smoking intensity.
Neoplasms
Heme oxygenase-1 mediates protective effects on inflammatory, catabolic and senescence responses induced by interleukin-1? in osteoarthritic osteoblasts.
Neoplasms
Hepatic ischemia/reperfusion injury is prevented by a novel matrix metalloproteinase inhibitor, ONO-4817.
Neoplasms
Hepatoprotective effect of forsythiaside a against acetaminophen-induced liver injury in zebrafish: Coupling network pharmacology with biochemical pharmacology.
Neoplasms
Herbal compound "Songyou Yin" reinforced the ability of interferon-alfa to inhibit the enhanced metastatic potential induced by palliative resection of hepatocellular carcinoma in nude mice.
Neoplasms
Herbal extract "Songyou Yin" inhibits tumor growth and prolongs survival in nude mice bearing human hepatocellular carcinoma xenograft with high metastatic potential.
Neoplasms
Hesperidin Prevents Nitric Oxide Deficiency-Induced Cardiovascular Remodeling in Rats via Suppressing TGF-?1 and MMPs Protein Expression.
Neoplasms
Hierarchical virtual screening of the dual MMP-2/HDAC-6 inhibitors from natural products based on pharmacophore models and molecular docking.
Neoplasms
HIF-1? contributes to hypoxia-induced invasion and metastasis of esophageal carcinoma via inhibiting E-cadherin and promoting MMP-2 expression.
Neoplasms
HIF-2? as a prognostic marker for breast cancer progression and patient survival.
Neoplasms
High expression levels of nuclear factor kappa B and gelatinases in the tumorigenesis of oral squamous cell carcinoma.
Neoplasms
High Expression of MMP-9 in Primary Tumors and High Preoperative MPO in Serum Predict Improved Prognosis in Colorectal Cancer with Operable Liver Metastases.
Neoplasms
High expression of tissue inhibitor of metalloproteinase-2 in serous ovarian carcinomas and the role of this expression in ovarian tumorigenesis.
Neoplasms
High galectin-1 expression correlates with poor prognosis and is involved in epithelial ovarian cancer proliferation and invasion.
Neoplasms
High Grade T1 Papillary Urothelial Bladder Cancer Shows Prominent Peritumoral Retraction Clefting.
Neoplasms
High level of MT-MMP expression is associated with invasiveness of cervical cancer cells.
Neoplasms
High levels of messenger RNAs for tissue inhibitors of metalloproteinases (TIMP-1 and TIMP-2) in primary breast carcinomas are associated with development of distant metastases.
Neoplasms
High levels of MMP-2, MMP-9, MT1-MMP and TIMP-2 mRNA correlate with poor survival in ovarian carcinoma.
Neoplasms
High levels of tissue inhibitor of metalloproteinase-1 predict poor outcome in patients with breast cancer.
Neoplasms
High levels of tissue inhibitor of metalloproteinase-2 (TIMP-2) expression are associated with poor outcome in invasive bladder cancer.
Neoplasms
High mobility group protein HMGI(Y) enhances tumor cell growth, invasion, and matrix metalloproteinase-2 expression in prostate cancer cells.
Neoplasms
High molecular weight hyaluronic acid down-regulates the gene expression of osteoarthritis-associated cytokines and enzymes in fibroblast-like synoviocytes from patients with early osteoarthritis.
Neoplasms
High threshold of ?1 integrin inhibition required to block collagen I-induced membrane type-1 matrix metalloproteinase (MT1-MMP) activation of matrix metalloproteinase 2 (MMP-2).
Neoplasms
High-grain diet feeding altered the composition and functions of the rumen bacterial community and caused the damage to the laminar tissues of goats.
Neoplasms
High-protein diet associated with resistance training reduces cardiac TNF-? levels and up-regulates MMP-2 activity in rats.
Neoplasms
High-throughput functional profiling of single adherent cells via hydrogel drop-screen.
Neoplasms
High-yield clicking and dissociation of doxorubicin nanoclusters exhibiting differential cellular uptakes and imaging.
Neoplasms
Highly expressed tumoral emmprin and stromal CD73 predict a poor prognosis for external auditory canal carcinoma.
Neoplasms
Histologic features of venous invasion, expression of vascular endothelial growth factor and matrix metalloproteinase-2 and matrix metalloproteinase-9, and the relation with liver metastasis in pancreatic cancer.
Neoplasms
Histone deacetylase inhibitor up-regulates RECK to inhibit MMP-2 activation and cancer cell invasion.
Neoplasms
Histone deacetylase inhibitor, apicidin, inhibits human ovarian cancer cell migration via class II histone deacetylase 4 silencing.
Neoplasms
Homology cloning of rat 72 kDa type IV collagenase: cytokine and second-messenger inducibility in glomerular mesangial cells.
Neoplasms
HOW EXPRESSIONS OF CLAUDIN-1 AND MMP-2 IN RETINOBLASTOMA CORRELATE WITH HISTOLOGICAL DIFFERENTIATION AND OPTIC NERVE INVASION.
Neoplasms
Human hemokinin-1 promotes migration of melanoma cells and increases MMP-2 and MT1-MMP expression by activating tumor cell NK1 receptors.
Neoplasms
Human keratinocytes express EMMPRIN, an extracellular matrix metalloproteinase inducer.
Neoplasms
Human mammary fibroblasts stimulate invasion of breast cancer cells in a three-dimensional culture and increase stroma development in mouse xenografts.
Neoplasms
Human mesenchymal stem cells play a dual role on tumor cell growth in vitro and in vivo.
Neoplasms
Human MT6-matrix metalloproteinase: identification, progelatinase A activation, and expression in brain tumors.
Neoplasms
Human protein kinase CK2 phosphorylates matrix metalloproteinase 2 and inhibits its activity.
Neoplasms
Humoral and cellular immunity induced by tumor cell vaccine based on the chicken xenogeneic homologous matrix metalloproteinase-2.
Neoplasms
Hyaluronan-binding protein 1 (HABP1/p32/gC1qR) induces melanoma cell migration and tumor growth by NF-kappa B dependent MMP-2 activation through integrin ?(v)?(3) interaction.
Neoplasms
Hydroxysafflor yellow A suppresses angiogenesis of hepatocellular carcinoma through inhibition of p38 MAPK phosphorylation.
Neoplasms
Hyperbaric oxygen activates discoidin domain receptor 2 via tumor necrosis factor-alpha and p38 pathway to increase vascular smooth muscle cells migration through matrix metalloproteinase 2.
Neoplasms
Hyperglycemia and T Cell infiltration are associated with stromal and epithelial prostatic hyperplasia in the nonobese diabetic mouse.
Neoplasms
Hypoxia influences vasculogenic mimicry channel formation and tumor invasion-related protein expression in melanoma.
Neoplasms
Hypoxia level and matrix metalloproteinases-2 and -9 activity in Lewis lung carcinoma: correlation with metastasis.
Neoplasms
Hypoxia suppresses E-cadherin and enhances matrix metalloproteinase-2 expression favoring esophageal carcinoma migration and invasion via hypoxia inducible factor-1 alpha activation.
Neoplasms
Hypoxia-Induced Cleavage Of Soluble ephrinA1 From Cancer Cells Is Mediated By MMP-2 And Associates With Angiogenesis In Oral Squamous Cell Carcinoma.
Neoplasms
Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche.
Neoplasms
Hypoxia-induced senescence contributes to the regulation of microenvironment in melanomas.
Neoplasms
IB05204, a dichloropyridodithienotriazine, inhibits angiogenesis in vitro and in vivo.
Neoplasms
Identification and characterization of human MT5-MMP, a new membrane-bound activator of progelatinase a overexpressed in brain tumors.
Neoplasms
Identification of an amino acid sequence from the laminin A chain that stimulates metastasis and collagenase IV production.
Neoplasms
Identification of Caspase-6 as a New Regulator of Alternatively Activated Macrophages.
Neoplasms
Identification of matrix metalloproteinases in canine cutaneous mast cell tumors.
Neoplasms
Identification of Non-Zinc Binding Inhibitors of MMP-2 Through Virtual Screening and Subsequent Rescoring.
Neoplasms
Identification of novel, functional genetic variants in the human matrix metalloproteinase-2 gene: role of Sp1 in allele-specific transcriptional regulation.
Neoplasms
Identification of patients with chronic obstructive pulmonary disease (COPD) by measurement of plasma biomarkers.
Neoplasms
Identification of substrate sequences for membrane type-1 matrix metalloproteinase using bacteriophage peptide display library.
Neoplasms
Identification, regulation and role of tissue inhibitor of metalloproteinases-4 (TIMP-4) in human platelets.
Neoplasms
IKK? Kinase Promotes Stemness, Migration, and Invasion in KRAS-Driven Lung Adenocarcinoma Cells.
Neoplasms
IL-10 inhibits the NF-?B and ERK/MAPK-mediated production of pro-inflammatory mediators by up-regulation of SOCS-3 in Trypanosoma cruzi-infected cardiomyocytes.
Neoplasms
IL-1?, IL-8, and Matrix Metalloproteinases-1, -2, and -10 Are Enriched upon Monocyte-Breast Cancer Cell Cocultivation in a Matrigel-Based Three-Dimensional System.
Neoplasms
Imatinib-associated matrix metalloproteinase suppression in p16-positive squamous cell carcinoma compared to HPV-negative HNSCC cells in vitro.
Neoplasms
Imbalance between serum matrix metalloproteinase-2 and its inhibitor as a predictor of recurrence of urothelial cancer.
Neoplasms
Imbalance of MMP-2 and MMP-9 expression versus TIMP-1 and TIMP-2 reflects increased invasiveness of human testicular germ cell tumours.
Neoplasms
Imetelstat (a telomerase antagonist) exerts off?target effects on the cytoskeleton.
Neoplasms
Immortalization of human aortic smooth muscle cells with origin-minus simian virus 40 DNA.
Neoplasms
Immunization with a Mimotope of GD2 Ganglioside Induces CD8+ T Cells That Recognize Cell Adhesion Molecules on Tumor Cells.
Neoplasms
Immunoassays of the metalloproteinase (MMP-2) and tissue inhibitor of metalloproteinase (TIMP 1 and 2) levels in noninvasive and metastatic PC-3 clones: effects of taxol.
Neoplasms
Immunocharacterization of matrix metalloproteinase-2 and matrix metalloproteinase-9 in canine transmissible venereal tumors.
Neoplasms
Immunocytochemical detection of matrix metalloproteinase expression in prostate cancer.
Neoplasms
Immunocytochemical detection of the expression of members of the matrix metalloproteinase family in adenocarcinomas of the pancreas.
Neoplasms
Immunoelectron microscopic localization of gelatinase A in human gastrointestinal and skin carcinomas: difference between cancer cells and fibroblasts.
Neoplasms
Immunoexpression of matrix metalloproteinase-2 (MMP-2) in malignant ovarian epithelial tumours.
Neoplasms
Immunoexpression of matrix metalloproteinases and their inhibitors in different areas of oral squamous cell carcinoma.
Neoplasms
Immunoexpression of Metalloproteinases 2 and 14 and TIMP-2 Inhibitor in Main Types of Primary Gastric Carcinomas and Lymph Node Metastasis.
Neoplasms
Immunoexpression of MMPs-1, -2, and -9 in ameloblastoma and odontogenic adenomatoid tumor.
Neoplasms
Immunogenicity moderation effect of interleukin-24 on myelogenous leukemia cells.
Neoplasms
Immunohistochemical analysis of reactive astrocytes around glioblastoma: an immunohistochemical study of postmortem glioblastoma cases.
Neoplasms
Immunohistochemical detection of matrix metalloproteinases (MMP) 1 and 2, and tissue inhibitor of metalloproteinase 2 (TIMP 2) in stage I and II endometrial cancer.
Neoplasms
Immunohistochemical detection of matrix metalloproteinases (MMP) 1 and 2, and tissue inhibitor of metalloproteinase 2 (TIMP 2) in stage IB cervical cancer.
Neoplasms
Immunohistochemical detection of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) in ameloblastomas.
Neoplasms
Immunohistochemical detection of membrane-type-1-matrix metalloproteinase in colorectal carcinoma.
Neoplasms
Immunohistochemical detection of the 150-kDa oxygen-regulated protein in bladder cancer.
Neoplasms
Immunohistochemical distribution of type IV collagenase in normal, benign, and malignant breast tissue.
Neoplasms
Immunohistochemical evaluation of MMP-2 and TIMP-2 in canine mammary tumours: A survival study.
Neoplasms
Immunohistochemical evaluation of type IV collagenase (72-kd metalloproteinase) in prostatic intraepithelial neoplasia.
Neoplasms
Immunohistochemical expression of matrix metalloproteinases 1, 2, 9, and 14 in dermatofibrosarcoma protuberans and common fibrous histiocytoma (dermatofibroma).
Neoplasms
Immunohistochemical expression of matrix metalloproteinases in ameloblastomas and pericoronal follicles.
Neoplasms
Immunohistochemical expression of MMP-2, MMP-9, and TIMP-2 in neuroblastoma: association with tumor progression and clinical outcome.
Neoplasms
Immunohistochemical expression of vascular endothelial growth factor, matrix metalloproteinase 2, and matrix metalloproteinase 9 in cutaneous melanocytic lesions.
Neoplasms
Immunohistochemical Expression Profiles of Cell Adhesion Molecules, Matrix Metalloproteinases and their Tissue Inhibitors in Central and Peripheral Neoplastic Foci of Feline Mammary Carcinoma.
Neoplasms
Immunohistochemical localization of matrix metalloproteinase 2 and its specific inhibitor TIMP-2 in neoplastic tissues with monoclonal antibodies.
Neoplasms
Immunohistochemical studies of the expression of matrix metalloproteinase-2 and metalloproteinase-9 in human prostate cancer.
Neoplasms
Immunohistochemical study of lung remodeling in mice exposed to cigarette smoke*.
Neoplasms
Immunohistochemical study of membrane type-matrix metalloproteinases (MT-MMPs) and matrix metalloproteinase-2 (MMP-2) in dermatofibroma and malignant fibrous histiocytoma.
Neoplasms
Immunohistochemical study of tumor necrosis factor-alpha, matrix metalloproteinase-12, and tissue inhibitor of metalloproteinase-2 on alveolar macrophages of BALB/c mice exposed to short-term cigarette smoke.
Neoplasms
Immunolocalization of matrix metallo-proteinases and their tissue inhibitor in human mammary pathology.
Neoplasms
Immunolocalizations of human gelatinase (type IV collagenase, MMP-9) and TIMP (tissue inhibitor of metalloproteinases) in normal epidermis and some epidermal tumors.
Neoplasms
Immunological characterization of cell-surface and soluble forms of membrane type 1 matrix metalloproteinase in human breast cancer cells and in fibroblasts.
Neoplasms
Immunotherapy Using Oxygenated Water and Tumor-Derived Exosomes Potentiates Antitumor Immune Response and Attenuates Malignancy Tendency in Mice Model of Breast Cancer.
Neoplasms
Impact and mechanism of non-steroidal anti-inflammatory drugs combined with chemotherapeutic drugs on human lung cancer-nude mouse transplanted tumors.
Neoplasms
Impact of CD68/(CD3+CD20) ratio at the invasive front of primary tumors on distant metastasis development in breast cancer.
Neoplasms
Impact of LIMK1, MMP2 and TNF-? variations for intracranial aneurysm in Japanese population.
Neoplasms
Impact of MMP-2 and MMP-9 enzyme activity on wound healing, tumor growth and RACPP cleavage.
Neoplasms
Impact of the biophysical features of a 3D gelatin microenvironment on glioblastoma malignancy.
Neoplasms
Improving Tumor Specificity and Anticancer Activity of Dasatinib by Dual-Targeted Polymeric Micelles.
Neoplasms
In situ injection of dual-delivery PEG based MMP-2 sensitive hydrogels for enhanced tumor penetration and chemo-immune combination therapy.
Neoplasms
In situ localization of gelatinolytic activity in the extracellular matrix of metastases of colon cancer in rat liver using quenched fluorogenic DQ-gelatin.
Neoplasms
In situ mRNA hybridization technique for analysis of metastasis-related genes in human colon carcinoma cells.
Neoplasms
In vitro and ex vivo vanadium antitumor activity in (TGF-?)-induced EMT. Synergistic activity with carboplatin and correlation with tumor metastasis in cancer patients.
Neoplasms
In vitro and in vivo antimetastatic effects of Terminalia catappa L. leaves on lung cancer cells.
Neoplasms
In vitro and in vivo evaluation of doxorubicin conjugates with the divalent peptide E-[c(RGDfK)2] that targets integrin alphavbeta3.
Neoplasms
In vitro and in vivo investigation of matrix metalloproteinase expression in metastatic tumor models.
Neoplasms
In vitro and in vivo matrix metalloproteinase expression after photodynamic therapy with a liposomal formulation of aminolevulinic acid and its methyl ester.
Neoplasms
In vitro assessment of liposomal neridronate on MDA-MB-231 human breast cancer cells.
Neoplasms
In vitro determination of basement membrane invasion predicts liver metastases in human gastrointestinal carcinoma.
Neoplasms
In vitro effects of meloxicam on metabolism in articular chondrocytes from dogs with naturally occurring osteoarthritis.
Neoplasms
In vitro expression of MMP-2 and MMP-9 in glioma cells following exposure to inflammatory mediators.
Neoplasms
In vitro infection of macrophages by HIV: correlation with cellular activation, synthesis of tumour necrosis factor alpha and proteolytic activity.
Neoplasms
In vitro inhibition of human MMP-2 collagenolytic and gelatinolytic activity by neutralizing monoclonal antibodies.
Neoplasms
In vitro irradiation of basement membrane enhances the invasiveness of breast cancer cells.
Neoplasms
In vitro modulation of MMP-2 and MMP-9 in adult human sarcoma cell lines by cytokines, inducers and inhibitors.
Neoplasms
In vitro modulation of MMP-2 and MMP-9 in human cervical and ovarian cancer cell lines by cytokines, inducers and inhibitors.
Neoplasms
In vitro modulation of MMP-2 and MMP-9 in pediatric human sarcoma cell lines by cytokines, inducers and inhibitors.
Neoplasms
In vitro modulation of the invasive and metastatic potentials of human renal cell carcinoma by interleukin-2 and/or interferon-alpha gene transfer.
Neoplasms
In vitro modulation of tumor progression-associated properties of hormone refractory prostate carcinoma cell lines by cytokines.
Neoplasms
In vivo characterization of activatable cell penetrating peptides for targeting protease activity in cancer.
Neoplasms
In vivo glioma growth requires host-derived matrix metalloproteinase 2 for maintenance of angioarchitecture.
Neoplasms
In vivo imaging of membrane type-1 matrix metalloproteinase with a novel activatable near-infrared fluorescence probe.
Neoplasms
In vivo imaging of tissue-remodeling activity involving infiltration of macrophages by a systemically administered protease-activatable probe in colon cancer tissues.
Neoplasms
In vivo optical imaging of MMP2 immuno protein antibody: tumor uptake is associated with MMP2 activity.
Neoplasms
In vivo self-assembly induced retention of gold nanoparticles for enhanced photothermal tumor treatment.
Neoplasms
In-capillary screening of matrix metalloproteinase inhibitors by electrophoretically mediated microanalysis with fluorescence detection.
Neoplasms
Increase in tissue inhibitor of metalloproteinase-2 (TIMP-2) levels and inhibition of MMP-2 activity in a metastatic breast cancer cell line by an anti-invasive small molecule SR13179.
Neoplasms
Increased expression and activation of matrix metalloproteinase-2 (MMP-2) in O-1N: hamster oral squamous cell carcinoma with high potential lymph node metastasis.
Neoplasms
Increased expression of avian erythroblastosis virus E26 oncogene homolog 1 in World Health Organization grade 1 meningiomas is associated with an elevated risk of recurrence and is correlated with the expression of its target genes matrix metalloproteinase-2 and MMP-9.
Neoplasms
Increased expression of matrix metalloproteinase 7 and 9 and membrane type 1-matrix metalloproteinase in esophageal squamous cell carcinomas.
Neoplasms
Increased expression of matrix metalloproteinase-2 (MMP-2) predicts tumour recurrence and unfavourable outcome in non-small cell lung cancer.
Neoplasms
Increased expression of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 is correlated with poor prognostic variables in patients with thymic epithelial tumors.
Neoplasms
Increased expression of matrix metalloproteinase-2 in oral cells after short-term stimulation and long-term usage of areca quid.
Neoplasms
Increased expression of matrix metalloproteinase-2 in the thickened intima of aged rats.
Neoplasms
Increased expression of matrix metalloproteinase-2: a diagnostic marker but not prognostic marker of papillary thyroid carcinoma.
Neoplasms
Increased expression of matrix metalloproteinases (MMP)-2, MMP-9, and the urokinase-type plasminogen activator is associated with progression from benign to advanced ovarian cancer.
Neoplasms
Increased expression of membrane type 1 matrix metalloproteinase and matrix metalloproteinase-2 with tumor dedifferentiation in hepatocellular carcinomas.
Neoplasms
Increased expression of seprase, a membrane-type serine protease, is associated with lymph node metastasis in human colorectal cancer.
Neoplasms
Increased expression of the 72-kd type IV collagenase in prostatic adenocarcinoma. Demonstration by immunohistochemistry and in situ hybridization.
Neoplasms
Increased expression of the Mr 72,000 type IV collagenase in human colonic adenocarcinoma.
Neoplasms
Increased expression of tissue inhibitor of metalloproteinase-2 in clear cell carcinoma of the ovary.
Neoplasms
Increased extracellular matrix remodeling is associated with tumor progression in human hepatocellular carcinomas.
Neoplasms
Increased gelatinase A (MMP-2) and cathepsin B activity in invasive tumor regions of human colon cancer samples.
Neoplasms
Increased gelatinase-A and gelatinase-B activities in malignant vs. benign breast tumors.
Neoplasms
Increased in situ gelatinolytic activity in renal cell tumor tissues correlates with tumor size, grade and vessel invasion.
Neoplasms
Increased invasion and matrix metalloproteinase-2 expression by Snail-induced mesenchymal transition in squamous cell carcinomas.
Neoplasms
Increased level of cytokines and matrix metalloproteinases in osteoarthritic subchondral bone.
Neoplasms
Increased matrix metalloproteinase 2 concentration and transcript expression in advanced colorectal carcinomas.
Neoplasms
Increased matrix metalloproteinase activation in esophageal squamous cell carcinoma.
Neoplasms
Increased matrix metalloproteinase-2 expression and reduced tissue factor pathway inhibitor-2 expression correlate with angiogenesis and early postoperative recurrence of pancreatic carcinoma.
Neoplasms
Increased matrix metalloproteinase-9 secretion in short-term tissue cultures of prostatic tumor cells.
Neoplasms
Increased matrix metalloproteinases 2 and 9 and tissue inhibitor of matrix metalloproteinase 2 expression is associated with progression from vulvar intraepithelial neoplasia to invasive carcinoma.
Neoplasms
Increased plasma MMP-2 protein expression in lymph node-positive patients with colorectal cancer.
Neoplasms
Increased serum 72 KDa metalloproteinase in serous ovarian tumors: comparison with CA 125.
Neoplasms
Increased Twist and ZEB2 expression in a cutaneous metastasis of high-grade glioma.
Neoplasms
Induction and stimulation of 92-kDa gelatinase/type IV collagenase production in osteosarcoma and fibrosarcoma cell lines by tumor necrosis factor alpha.
Neoplasms
Induction of cancer cell-specific death via MMP2 promoterdependent Bax expression.
Neoplasms
Induction of fibroblast 92 kDa gelatinase/type IV collagenase expression by direct contact with metastatic tumor cells.
Neoplasms
Induction of M(r) 92,000 type IV collagenase expression in a squamous cell carcinoma cell line by fibroblasts.
Neoplasms
Induction of matrix metalloproteinase MMP-9 (92-kDa gelatinase) by retinoic acid in human neuroblastoma SKNBE cells: relevance to neuronal differentiation.
Neoplasms
Induction of membrane-type matrix metalloproteinase-1 stimulates angiogenic activities of bovine aortic endothelial cells.
Neoplasms
Induction of p53 without increase in p21WAF1 in betulinic acid-mediated cell death is preferential for human metastatic melanoma.
Neoplasms
Induction of Senescence in Cancer Cells by a Novel Combination of Cucurbitacin B and Withanone: Molecular Mechanism and Therapeutic Potential.
Neoplasms
Induction of vasculogenic mimicry overrides VEGF-A silencing and enriches stem-like cancer cells in melanoma.
Neoplasms
Infiltration of blood outgrowth endothelial cells into tumor spheroids: role of matrix metalloproteinases and irradiation.
Neoplasms
Infiltration of F98 glioma cells in Fischer rat brain is temporary stimulated by radiation.
Neoplasms
Inflammatory cytokine modulation of matrix metalloproteinase expression and invasiveness of glioma cells in a 3-dimensional collagen matrix.
Neoplasms
Inflammatory Cytokines and Matrix Metalloproteinases in the Synovial Fluid After Intra-articular Ankle Fracture.
Neoplasms
Inflammatory cytokines and matrix metalloproteinases in the synovial fluid after intra-articular elbow fracture.
Neoplasms
Influence of hydrogencalcium salts of oxidized cellulose on MMP-2, MMP-9 and TNF-? production and wound healing in non-healing wounds.
Neoplasms
Influence of microenvironments on microcirculation patterns and tumor invasion-related protein expression in melanoma.
Neoplasms
Influence of MMP-2 and MMP-9 promoter polymorphisms on gene expression and clinical outcome of non-small cell lung cancer.
Neoplasms
Influence of New Synthetic Xanthones on the Proliferation and Migration Potential of Cancer Cell Lines in Vitro.
Neoplasms
Influence of oleic acid on the expression, activation and activity of gelatinase A produced by oncogene-transformed human bronchial epithelial cells.
Neoplasms
Influence of organ environment on extracellular matrix degradative activity and metastasis of human colon carcinoma cells.
Neoplasms
Influence of the host microenvironment on the clonal selection of human colon carcinoma cells during primary tumor growth and metastasis.
Neoplasms
Infrequent stromal expression of gelatinase A and intact basement membrane in intraductal neoplasms of the pancreas.
Neoplasms
Inhibition activity of sulfated polysaccharide of Sepiella maindroni ink on matrix metalloproteinase (MMP)-2.
Neoplasms
Inhibition by galloylglucose (GG6-10) of tumor invasion through extracellular matrix and gelatinase-mediated degradation of type IV collagens by metastatic tumor cells.
Neoplasms
Inhibition by retinoic acid of type IV collagenolysis and invasion through reconstituted basement membrane by metastatic rat mammary adenocarcinoma cells.
Neoplasms
Inhibition of AIDS-Kaposi's sarcoma cell induced endothelial cell invasion by TIMP-2 and a synthetic peptide from the metalloproteinase propeptide: implications for an anti-angiogenic therapy.
Neoplasms
Inhibition of arachidonic acid metabolism decreases tumor cell invasion and matrix metalloproteinase expression.
Neoplasms
Inhibition of B16 melanoma metastases with the ruthenium complex imidazolium trans-imidazoledimethylsulfoxide-tetrachlororuthenate and down-regulation of tumor cell invasion.
Neoplasms
Inhibition of Breast Cancer Metastasis by Presurgical Treatment with an Oral Matrix Metalloproteinase Inhibitor: A Preclinical Proof-of-Principle Study.
Neoplasms
Inhibition of Caco-2 colon, MCF-7 and Hs578T breast, and DU 145 prostatic cancer cell proliferation by water-soluble black bean condensed tannins.
Neoplasms
Inhibition of calcium-calmodulin-dependent kinase II suppresses cardiac fibroblast proliferation and extracellular matrix secretion.
Neoplasms
Inhibition of cancer migration and invasion by knocking down delta-5-desaturase in COX-2 overexpressed cancer cells.
Neoplasms
Inhibition of cervical lymph node metastasis by marimastat (BB-2516) in an orthotopic oral squamous cell carcinoma implantation model.
Neoplasms
Inhibition of collagenases from mouse lung carcinoma cells by green tea catechins and black tea theaflavins.
Neoplasms
Inhibition of cyclooxygenase-2 suppresses the invasiveness of oral squamous cell carcinoma cell lines via down-regulation of matrix metalloproteinase-2 production and activation.
Neoplasms
Inhibition of gelatinase A (MMP-2) by batimastat and captopril reduces tumor growth and lung metastases in mice bearing Lewis lung carcinoma.
Neoplasms
Inhibition of Histone Deacetylase Attenuates Hypoxia-Induced Migration and Invasion of Cancer Cells via the Restoration of RECK Expression.
Neoplasms
Inhibition of human glioma U251 cells growth in vitro and in vivo by hydroxyapatite nanoparticle-assisted delivery of short hairpin RNAs against SATB1.
Neoplasms
Inhibition of human lung cancer cells by anti-p21Ras scFv mediated by the activatable cell-penetrating peptide.
Neoplasms
Inhibition of invasion, gelatinase activity, tumor take and metastasis of malignant cells by N-acetylcysteine.
Neoplasms
Inhibition of matrix metalloproteinase 2 maturation and HT1080 invasiveness by a synthetic furin inhibitor.
Neoplasms
Inhibition of matrix metalloproteinase-2 expression and bladder carcinoma metastasis by halofuginone.
Neoplasms
Inhibition of matrix metalloproteinase-mediated periodontal bone loss in rats: a comparison of 6 chemically modified tetracyclines.
Neoplasms
Inhibition of metalloproteinases derived from tumours: new insights in the treatment of human glioblastoma.
Neoplasms
Inhibition of metastasis, angiogenesis, and tumor growth by Chinese herbal cocktail Tien-Hsien Liquid.
Neoplasms
Inhibition of MMP-2 and MMP-9 decreases cellular migration, and angiogenesis in in vitro models of retinoblastoma.
Neoplasms
Inhibition of organ invasion by the matrix metalloproteinase inhibitor batimastat (BB-94) in two human colon carcinoma metastasis models.
Neoplasms
Inhibition of osteolytic bone metastasis of breast cancer by combined treatment with the bisphosphonate ibandronate and tissue inhibitor of the matrix metalloproteinase-2.
Neoplasms
Inhibition of SPHK1 suppresses phorbol 12-myristate 13-acetate-induced metastatic phenotype in colorectal cancer HT-29 cells.
Neoplasms
Inhibition of the p38 mitogen-activated protein kinase by SB 203580 blocks PMA-induced Mr 92,000 type IV collagenase secretion and in vitro invasion.
Neoplasms
Inhibition of Tumor Growth and Metastasis by Non-Small Cell Lung Cancer Cells Transfected with Cyclin D1-Targeted siRNA.
Neoplasms
Inhibition of tumor growth by ?-elemene through downregulation of the expression of uPA, uPAR, MMP-2, and MMP-9 in a murine intraocular melanoma model.
Neoplasms
Inhibition of tumor growth by quercetin with increase of survival and prevention of cachexia in Walker 256 tumor-bearing rats.
Neoplasms
Inhibition of tumor-cell invasion with chlorotoxin-bound superparamagnetic nanoparticles.
Neoplasms
Inhibitors of collagenase IV and cell adhesion reduce the invasive activity of malignant tumour cells.
Neoplasms
Inhibitory effect of acetylsalicylic acid on metalloproteinase activity in human lung adenocarcinoma at different stages of differentiation.
Neoplasms
Inhibitory effect of aminoethyl-chitooligosaccharides on invasion of human fibrosarcoma cells.
Neoplasms
Inhibitory effect of chitooligosaccharides on matrix metalloproteinase-9 in human fibrosarcoma cells (HT1080).
Neoplasms
Inhibitory effect of Cho-Deung-San on human aortic smooth muscle cell migration induced by TNF-alpha through inhibition of matrix metalloproteinase-2 and -9 activity.
Neoplasms
Inhibitory effect of green tea polyphenols on membrane-type 1 matrix metalloproteinase, MT1-MMP.
Neoplasms
Inhibitory effect of isomorellin on cholangiocarcinoma cells via suppression of NF-?B translocation, the phosphorylated p38 MAPK pathway and MMP-2 and uPA expression.
Neoplasms
Inhibitory effect of norcantharidin on melanoma tumor growth and vasculogenic mimicry by suppressing MMP-2 expression.
Neoplasms
Inhibitory effect of siRNA-Annexin A7 on growth, migration, and invasion in BGC823 cells and gastric cancer xenograftsin nude mice.
Neoplasms
Inhibitory effects of a nutrient mixture on human testicular cancer cell line NT 2/DT matrigel invasion and MMP activity.
Neoplasms
Inhibitory Effects of a Reengineered Anthrax Toxin on Canine Oral Mucosal Melanomas.
Neoplasms
Inhibitory effects of caffeic acid phenethyl ester on cancer cell metastasis mediated by the down-regulation of matrix metalloproteinase expression in human HT1080 fibrosarcoma cells.
Neoplasms
Inhibitory effects of Chanling Gao on the proliferation and liver metastasis of transplanted colorectal cancer in nude mice.
Neoplasms
Inhibitory Effects of Dried Longan (Euphoria longana Lam.) Seed Extract on Invasion and Matrix Metalloproteinases of Colon Cancer Cells.
Neoplasms
Inhibitory Effects of Ganoderma lucidum on Tumorigenesis and Metastasis of Human Hepatoma Cells in Cells and Animal Models.
Neoplasms
Inhibitory effects of GL-V9 on the invasion of human breast carcinoma cells by downregulating the expression and activity of matrix metalloproteinase-2/9.
Neoplasms
Inhibitory effects of polysaccharide extract from Spirulina platensis on corneal neovascularization.
Neoplasms
Inhibitory effects of ubenimex (bestatin) on the invasion of uterine cervical carcinoma cells and their production and activation of gelatinase A.
Neoplasms
Inorganic sulfur reduces the motility and invasion of MDA-MB-231 human breast cancer cells.
Neoplasms
Insight into the structural requirement of aryl sulphonamide based gelatinases (MMP-2 and MMP-9) inhibitors - Part I: 2D-QSAR, 3D-QSAR topomer CoMFA and Naïve Bayes studies - First report of 3D-QSAR Topomer CoMFA analysis for MMP-9 inhibitors and jointly inhibitors of gelatinases together.
Neoplasms
Insulin like growth factor-1 selectively regulates the expression of matrix metalloproteinase-2 in malignant H-ras transformed cells.
Neoplasms
Insulin-like growth factor binding protein 2 enhances glioblastoma invasion by activating invasion-enhancing genes.
Neoplasms
Integrating macrophages into organotypic co-cultures: a 3D in vitro model to study tumor-associated macrophages.
Neoplasms
Integration of Dual Targeting and Dual Therapeutic Modules Endows Self-Assembled Nanoparticles with Anti-Tumor Growth and Metastasis Functions.
Neoplasms
Integrin-linked kinase regulates osteopontin-dependent MMP-2 and uPA expression to convey metastatic function in murine mammary epithelial cancer cells.
Neoplasms
Integrin-mediated active tumor targeting and tumor microenvironment response dendrimer-gelatin nanoparticles for drug delivery and tumor treatment.
Neoplasms
Intein-mediated site-specific synthesis of tumor-targeting protein delivery system: Turning PEG dilemma into prodrug-like feature.
Neoplasms
Interaction between angiotensin II and relaxin 2 in the progress of growth and spread of prostate cancer cells.
Neoplasms
Interaction of cocultured decidual endothelial cells and cytotrophoblasts in preeclampsia.
Neoplasms
Interleukin 10 (IL-10) inhibition of primary human prostate cell-induced angiogenesis: IL-10 stimulation of tissue inhibitor of metalloproteinase-1 and inhibition of matrix metalloproteinase (MMP)-2/MMP-9 secretion.
Neoplasms
Interleukin 10 blocks matrix metalloproteinase-2 and membrane type 1-matrix metalloproteinase synthesis in primary human prostate tumor lines.
Neoplasms
Interleukin-1 and tumor necrosis factor-alpha induce collagenolysis and bone resorption by regulation of matrix metalloproteinase-2 in mouse calvarial bone cells.
Neoplasms
Interleukin-1 beta induces differential gene expression in aortic smooth muscle cells.
Neoplasms
Interleukin-10 induced activating transcription factor 3 transcriptional suppression of matrix metalloproteinase-2 gene expression in human prostate CPTX-1532 Cells.
Neoplasms
Interleukin-6 expression by interactions between gynecologic cancer cells and human mesenchymal stem cells promotes epithelial-mesenchymal transition.
Neoplasms
Interpretation of immunohistochemistry data of tumor should consider microenvironmental factors.
Neoplasms
Interpreting gelatinase activity in tumor tissue and serum as a prognostic marker of naturally developing canine tumors.
Neoplasms
Intracellular activation of gelatinase A (72-kDa type IV collagenase) by normal fibroblasts.
Neoplasms
Intracellular expression of a single-chain antibody directed against type IV collagenase inhibits the growth of lung cancer xenografts in nude mice.
Neoplasms
Intracellular localization of matrix metalloproteinases and their inhibitors in cultured tumor cell lines: flow cytometric analysis.
Neoplasms
Intratumoral heterogeneity and inverse correlation between expression of E-cadherin and collagenase type IV in human gastric carcinomas.
Neoplasms
Intratumoral macrophage counts correlate with tumor progression in colorectal cancer.
Neoplasms
Invasion and metastases in gastric cancer: in vitro and in vivo models with clinical correlations.
Neoplasms
Invasion and metastasis: the expression and significance of matrix metalloproteinases in carcinomas of the lung.
Neoplasms
Invasive ability of human renal cell carcinoma cell line Caki-2 is accelerated by gamma-aminobutyric acid, via sustained activation of ERK1/2 inducible matrix metalloproteinases.
Neoplasms
Investigating the Cellular Specificity in Tumors of a Surface-Converting Nanoparticle by Multimodal Imaging.
Neoplasms
Investigation of a MMP-2 activity-dependent anchoring probe for nuclear imaging of cancer.
Neoplasms
Investigation of MMP-2 and -9 in a highly invasive A431 tumor cell sub-line selected from a Boyden chamber assay.
Neoplasms
Investigation of novel circulating proteins, germ line single-nucleotide polymorphisms, and molecular tumor markers as potential efficacy biomarkers of first-line sunitinib therapy for advanced renal cell carcinoma.
Neoplasms
Involvement of focal adhesion kinase in cellular invasion of head and neck squamous cell carcinomas via regulation of MMP-2 expression.
Neoplasms
Involvement of matrix metalloproteinase activity in hormone-induced mammary tumor regression.
Neoplasms
Involvement of matrix metalloproteinase-2 activity in invasion and metastasis of pancreatic carcinoma.
Neoplasms
Involvement of MMP-2 in adriamycin resistance dependent on ERK1/2 signal pathway in human osteosarcoma MG-63 cells.
Neoplasms
Involvement of PI3K/PTEN/AKT/mTOR pathway in invasion and metastasis in hepatocellular carcinoma: Association with MMP-9.
Neoplasms
Involvement of plasmin-mediated extracellular activation of progalanin in angiogenesis.
Neoplasms
Ionizing radiation-inducible miR-494 promotes glioma cell invasion through EGFR stabilization by targeting p190B RhoGAP.
Neoplasms
Irradiation of normal mouse tissue increases the invasiveness of mammary cancer cells.
Neoplasms
Isoalvaxanthone inhibits colon cancer cell proliferation, migration and invasion through inactivating Rac1 and AP-1.
Neoplasms
Isolation and characterization of human monoclonal antibodies specific to MMP-1A, MMP-2 and MMP-3.
Neoplasms
Isolation and characterization of novel RECK tumor suppressor gene splice variants.
Neoplasms
Ito cell morphology, alpha-smooth muscle actin and collagen type IV expression in the liver of patients with gastric and colorectal tumors.
Neoplasms
JunB promotes cell invasion and angiogenesis in VHL-defective renal cell carcinoma.
Neoplasms
JWA suppresses tumor angiogenesis via Sp1-activated MMP-2 and its prognostic significance in human gastric cancer.
Neoplasms
Ketoprofen in topical formulation decreases the matrix metalloproteinase-2 expression and pulmonary metastatic incidence in nude mice with osteosarcoma.
Neoplasms
KI-67 AND hTERT expression can aid in the distinction between malignant and benign pheochromocytoma and paraganglioma.
Neoplasms
Kisspeptin?13 inhibits bleomycin?induced pulmonary fibrosis through GPR54 in mice.
Neoplasms
Knockdown of PTTG1 inhibits the growth and invasion of lung adenocarcinoma cells through regulation of TGFB1/SMAD3 signaling.
Neoplasms
Korean Scutellaria baicalensis water extract inhibits cell cycle G1/S transition by suppressing cyclin D1 expression and matrix-metalloproteinase-2 activity in human lung cancer cells.
Neoplasms
Kupffer cell-derived 95-kd type IV collagenase/gelatinase B: characterization and expression in cultured cells.
Neoplasms
l-cysteine as a regulator for arsenic-mediated cancer-promoting and anti-cancer effects.
Neoplasms
LABAZ1: A metastatic tumor model for renal cell carcinoma expressing the carbonic anhydrase type 9 tumor antigen.
Neoplasms
Label-free colorimetric detection of gelatinases on nanoporous silicon photonic films.
Neoplasms
Laminin-5 gamma 2 chain and matrix metalloproteinase-2 may trigger colorectal carcinoma invasiveness through formation of budding tumor cells.
Neoplasms
Laminin-5 gamma2 chain and matrix metalloproteinase-2 expression in the neoplastic changes of uterine cervical squamous epithelium.
Neoplasms
Laminin-alpha1-chain sequence Leu-Gln-Val-Gln-Leu-Ser-Ile-Arg (LQVQLSIR) enhances murine melanoma cell metastases.
Neoplasms
Largazole, a class I histone deacetylase inhibitor, enhances TNF-?-induced ICAM-1 and VCAM-1 expression in rheumatoid arthritis synovial fibroblasts.
Neoplasms
Lefty peptides, derived by MMP2 cleavage, act as a new class of gelatinase A inhibitor.
Neoplasms
Leptin produced by obese adipose stromal/stem cells enhances proliferation and metastasis of estrogen receptor positive breast cancers.
Neoplasms
Leptomycin B reduces matrix metalloproteinase-9 expression and suppresses cutaneous inflammation.
Neoplasms
Levels of angiogenesis and expression of angiogenesis-related genes are prognostic for organ-specific metastasis of renal cell carcinoma.
Neoplasms
Levels of Circulating TIMP-2 and MMP2-TIMP2 Complex Are Decreased in Squamous Cervical Carcinoma.
Neoplasms
Levels of matrix metalloproteases in bladder cancer correlate with tumor grade and invasion.
Neoplasms
Licochalcone A attenuates abdominal aortic aneurysm induced by angiotensin II via regulating the miR-181b/SIRT1/HO-1 signaling.
Neoplasms
Limited processing of pro-matrix metalloprotease-2 (gelatinase A) overexpressed by transfection in PC-3 human prostate tumor cells: association with restricted cell surface localization of membrane-type matrix metalloproteinase-1.
Neoplasms
Limited value of preoperative serum analyses of matrix metalloproteinases (MMP-2, MMP-9) and tissue inhibitors of matrix metalloproteinases (TIMP-1, TIMP-2) in colorectal cancer.
Neoplasms
Lipid-soluble ginseng extract inhibits invasion and metastasis of B16F10 melanoma cells.
Neoplasms
Lipopolysaccharide-induced metastatic growth is associated with increased angiogenesis, vascular permeability and tumor cell invasion.
Neoplasms
Liposome-encapsulated hemoglobin enhances chemotherapy to suppress metastasis in mice.
Neoplasms
Liver cancer protease activity profiles support therapeutic options with matrix metalloproteinase-activatable oncolytic measles virus.
Neoplasms
LncRNA GAS6 antisense RNA 1 facilitates the tumorigenesis of clear cell renal cell carcinoma by regulating the AMP-activated protein kinase/mTOR signaling pathway.
Neoplasms
Local antimicrobial, protease and cytokine defense systems in psoriatic skin.
Neoplasms
Local cytokines induce differential expression of matrix metalloproteinases but not their tissue inhibitors in human endometrial fibroblasts.
Neoplasms
Localization and quantification of mRNA for matrix metalloproteinase-2 (MMP-2) and tissue inhibitor of matrix metalloproteinase-2 (TIMP-2) in human benign and malignant prostatic tissue.
Neoplasms
Localization of messenger RNA for tissue inhibitor of metalloproteinases-1 and type IV collagenases/gelatinases in monkey hepatocellular carcinomas.
Neoplasms
Localization of the 92 kd gelatinase mRNA in squamous cell and adenocarcinomas of the lung using in situ hybridization.
Neoplasms
Locally advanced breast carcinoma treated with neoadjuvant chemotherapy: are the changes in serum levels of YKL-40, MMP-2 and MMP-9 correlated with tumor response?
Neoplasms
Location of 72-kd metalloproteinase (type IV collagenase) in untreated prostatic adenocarcinoma.
Neoplasms
Long Noncoding RNA HOTAIR Contributes to Progression in Hepatocellular Carcinoma by Sponging miR-217-5p.
Neoplasms
Loss of Inhibitor of Growth (ING-4) Is Implicated in the Pathogenesis and Progression of Human Astrocytomas.
Neoplasms
Loss of Suppressors of Cytokine Signaling 3 Promotes Aggressiveness in Hepatocellular Carcinoma.
Neoplasms
Low density lipoprotein receptor-related protein mediates endocytic clearance of pro-MMP-2.TIMP-2 complex through a thrombospondin-independent mechanism.
Neoplasms
Low expression of reversion-inducing cysteine-rich protein with Kazal motifs (RECK) indicates a shorter survival after resection in patients with adenocarcinoma of the lung.
Neoplasms
Low serum level of pro-matrix metalloproteinase 2 correlates with aggressive behavior in breast carcinoma.
Neoplasms
Low-density lipoprotein receptor-related protein contributes to the antiangiogenic activity of thrombospondin-2 in a murine glioma model.
Neoplasms
Low-Dose Radiation Enhanced Inhibition of Breast Tumor Xenograft and Reduced Myocardial Injury Induced by Doxorubicin.
Neoplasms
LOX inhibition downregulates MMP-2 and MMP-9 in gastric cancer tissues and cells.
Neoplasms
Luteolin inhibits IL-1?-induced in?ammation in rat chondrocytes and attenuates osteoarthritis progression in a rat model.
Neoplasms
Luteolin inhibits the proliferation, adhesion, migration and invasion of choroidal melanoma cells in vitro.
Neoplasms
Lymph Node Metastasis of Gastric Cancer Is Associated with the Interaction Between Poly (ADP-Ribose) Polymerase 1 and Matrix Metallopeptidase 2.
Neoplasms
Lymph node micrometastasis and its correlation with MMP-2 expression in gastric carcinoma.
Neoplasms
Lymphovascular invasion is associated with poor survival in gastric cancer: an application of gene-expression and tissue array techniques.
Neoplasms
Macrophage interactions with collecting duct epithelial cells are capable of driving tubulointerstitial inflammation and fibrosis in immunoglobulin A nephropathy.
Neoplasms
Macrophages Polarized by Expression of ToxoGRA15II Inhibit Growth of Hepatic Carcinoma.
Neoplasms
Magnetic Semiconductor Gd-Doping CuS Nanoparticles as Activatable Nanoprobes for Bimodal Imaging and Targeted Photothermal Therapy of Gastric Tumors.
Neoplasms
Magnolol suppresses the proliferation and invasion of cholangiocarcinoma cells via inhibiting the NF-?B signaling pathway.
Neoplasms
Major co-localization of the extracellular-matrix degradative enzymes heparanase and gelatinase in tertiary granules of human neutrophils.
Neoplasms
Malignancy of bladder cancer cells is enhanced by tumor-associated fibroblasts through a multifaceted cytokine-chemokine loop.
Neoplasms
Malignant Fibrous Histiocytoma, Aggressive Fibromatosis and Benign Fibrous Tumors Express mRNA for the Metalloproteinase Inducer EMMPRIN and the Metalloproteinases MMP-2 and MT1-MMP.
Neoplasms
Malignant progression and blockade of angiogenesis in a murine transgenic model of neuroblastoma.
Neoplasms
Manipulation of TAMs functions to facilitate the immune therapy effects of immune checkpoint antibodies.
Neoplasms
Marked acceleration of the metastatic phenotype of a rat bladder carcinoma cell line by the expression of human gelatinase A.
Neoplasms
Marked induction of gelatinases, especially type B, in host fibroblasts by human ovarian cancer cells in athymic mice.
Neoplasms
Markers of immune activation and viral load in HIV-associated sensory neuropathy.
Neoplasms
Maternal infection with Schistosoma japonicum induces a profibrotic response in neonates.
Neoplasms
Mathematical modeling of cancer invasion: the role of membrane-bound matrix metalloproteinases.
Neoplasms
Matrilysin (MMP-7) promotes invasion of ovarian cancer cells by activation of progelatinase.
Neoplasms
Matrilysin-1 (MMP-7) and MMP-19 are expressed by Paget's cells in extramammary Paget's disease.
Neoplasms
Matrix Metalloprotease 2-Responsive Multifunctional Liposomal Nanocarrier for Enhanced Tumor Targeting.
Neoplasms
Matrix metalloproteinase (MMP) inhibition selectively decreases type II MMP activity in a murine model of pancreatic cancer.
Neoplasms
Matrix metalloproteinase (MMP-2 and MMP-9) and steroid receptor expressions in feline mammary tumors.
Neoplasms
Matrix metalloproteinase 2 (gelatinase A) is related to migration of keratinocytes.
Neoplasms
Matrix metalloproteinase 2 (MMP-2) and its tissue inhibitor 2 (TIMP-2) in pancreatic cancer (PC).
Neoplasms
Matrix metalloproteinase 2 (MMP-2) immunoreactive protein is associated with poor grade and survival in brain neoplasms.
Neoplasms
Matrix metalloproteinase 2 and 9 activity in patients with colorectal cancer liver metastasis.
Neoplasms
Matrix metalloproteinase 2 and matrix metalloproteinase 9 expression in human oral squamous cell carcinoma and the effect of protein kinase C inhibitors: preliminary observations.
Neoplasms
Matrix metalloproteinase 2 and tissue inhibitor of matrix metalloproteinases 2 in the diagnosis of colorectal adenoma and cancer patients.
Neoplasms
Matrix metalloproteinase 2 contributes to aggressive phenotype, epithelial-mesenchymal transition and poor outcome in nasopharyngeal carcinoma.
Neoplasms
Matrix metalloproteinase 2 immunoreactive protein appears early in cervical epithelial dedifferentiation.
Neoplasms
Matrix metalloproteinase 2 in tumor cell-induced platelet aggregation: regulation by nitric oxide.
Neoplasms
Matrix metalloproteinase 9 expression is induced by Epstein-Barr virus latent membrane protein 1 C-terminal activation regions 1 and 2.
Neoplasms
Matrix metalloproteinase activity in tumor, stromal tissue, and serum from cats with malignancies.
Neoplasms
Matrix metalloproteinase and its drug targets therapy in solid and hematological malignancies: An overview.
Neoplasms
Matrix metalloproteinase expression in malignant melanomas: tumor-extracellular matrix interactions in invasion and metastasis.
Neoplasms
Matrix metalloproteinase expression in normal skin associated with basal cell carcinoma and in distal skin from the same patients.
Neoplasms
Matrix metalloproteinase expression is related to angiogenesis and histologic grade in spindle cell soft tissue neoplasms of the extremities.
Neoplasms
Matrix metalloproteinase induction in the tumor stroma does not depend on CD147 expression in murine B16 melanoma.
Neoplasms
Matrix metalloproteinase inhibition improves survival in an orthotopic model of human pancreatic cancer.
Neoplasms
Matrix metalloproteinase inhibitor COL-3 in the treatment of AIDS-related Kaposi's sarcoma: a phase I AIDS malignancy consortium study.
Neoplasms
Matrix metalloproteinase inhibitor MMI-166 inhibits lymphogenous metastasis in an orthotopically implanted model of lung cancer.
Neoplasms
Matrix metalloproteinase production by bone marrow mononuclear cells from normal individuals and patients with acute and chronic myeloid leukemia or myelodysplastic syndromes.
Neoplasms
Matrix metalloproteinase production by cultured human endometrial stromal cells: identification of interstitial collagenase, gelatinase-A, gelatinase-B, and stromelysin-1 and their differential regulation by interleukin-1 alpha and tumor necrosis factor-alpha.
Neoplasms
Matrix Metalloproteinase Responsive Nanoparticles for Synergistic Treatment of Colorectal Cancer via Simultaneous Anti-Angiogenesis and Chemotherapy.
Neoplasms
Matrix metalloproteinase-1 is associated with poor prognosis in oesophageal cancer.
Neoplasms
Matrix metalloproteinase-2 (-1306 c>t) promoter polymorphism and risk of colorectal cancer in the Saudi population.
Neoplasms
Matrix metalloproteinase-2 (72 kD type IV collagenase) expression occurs in the early stage of human melanocytic tumour progression and may have prognostic value.
Neoplasms
Matrix metalloproteinase-2 (MMP-2) and -9 (MMP-9) and their tissue inhibitors (TIMP-1 and TIMP-2) in differential diagnosis between low malignant potential (LMP) and malignant ovarian tumours.
Neoplasms
Matrix metalloproteinase-2 (MMP-2) and its tissue inhibitor (TIMP-2) are prognostic factors in cervical cancer, related to invasive disease but not to high-risk human papillomavirus (HPV) or virus persistence after treatment of CIN.
Neoplasms
Matrix metalloproteinase-2 (MMP-2) and MMP-9 expression in invasive ductal carcinoma of the breast.
Neoplasms
Matrix metalloproteinase-2 (MMP-2) expression and regulation by tumor necrosis factor alpha (TNFalpha) in the bovine corpus luteum.
Neoplasms
Matrix metalloproteinase-2 (MMP-2) immunoreactive protein--a new prognostic marker in uveal melanoma?
Neoplasms
Matrix metalloproteinase-2 (MMP-2) is associated with survival in breast carcinoma.
Neoplasms
Matrix metalloproteinase-2 (MMP-2) is associated with the risk for a relapse in postmenopausal patients with node-positive breast carcinoma treated with antiestrogen adjuvant therapy.
Neoplasms
Matrix metalloproteinase-2 (MMP-2): A major player in the progression of systemic malignancies besides endometrial serous carcinomas.
Neoplasms
Matrix Metalloproteinase-2 -1306 C>T Gene Polymorphism is Associated with Reduced Risk of Cancer: a Meta-analysis.
Neoplasms
Matrix metalloproteinase-2 and -9 activities correlate with the disease-free survival of oral squamous cell carcinoma patients.
Neoplasms
Matrix metalloproteinase-2 and -9 as promising benefactors in development, plasticity and repair of the nervous system.
Neoplasms
Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9 expression in the biological behavior of Canine and Feline Meningioma.
Neoplasms
Matrix metalloproteinase-2 and tissue inhibitor of metallo-proteinase-2 in colorectal carcinoma invasion and metastasis.
Neoplasms
Matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 expression and synthetic matrix metalloproteinase-2 inhibitor binding in ovarian carcinomas and tumor cell lines.
Neoplasms
Matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 expression in paediatric tumour cells. Effects of tumour cell proliferation modulators on gelatinolytic activity.
Neoplasms
Matrix metalloproteinase-2 as a superior biomarker for peritoneal deterioration in peritoneal dialysis.
Neoplasms
Matrix metalloproteinase-2 cleavage of the ?1 integrin ectodomain facilitates colon cancer cell motility.
Neoplasms
Matrix Metalloproteinase-2 Conditions Human Dendritic Cells to Prime Inflammatory T(H)2 Cells via an IL-12- and OX40L-Dependent Pathway.
Neoplasms
Matrix metalloproteinase-2 contributes to tumor necrosis factor alpha induced apoptosis in cultured rat cardiac myocytes.
Neoplasms
Matrix metalloproteinase-2 expression correlates with cavernous sinus invasion in pituitary adenomas.
Neoplasms
Matrix metalloproteinase-2 expression correlates with morphological and immunohistochemical epithelial characteristics in synovial sarcoma.
Neoplasms
Matrix metalloproteinase-2 expression in laryngeal preneoplastic and neoplastic lesions.
Neoplasms
Matrix metalloproteinase-2 expression in stromal tissues is a consistent prognostic factor in stage II colon cancer.
Neoplasms
Matrix metalloproteinase-2 gene polymorphism is not associated with increased glioblastoma multiforme susceptibility: an Indian institutional experience.
Neoplasms
Matrix metalloproteinase-2 immunoreactive protein as a prognostic marker in bladder cancer.
Neoplasms
Matrix metalloproteinase-2 immunoreactive protein: a marker of aggressiveness in breast carcinoma.
Neoplasms
Matrix metalloproteinase-2 in pancreatic juice for diagnosis of pancreatic cancer.
Neoplasms
Matrix metalloproteinase-2 involvement in breast cancer progression: a mini-review.
Neoplasms
Matrix metalloproteinase-2 is expressed in melanoma-associated spongiform scleropathy.
Neoplasms
Matrix metalloproteinase-2 is required for the switch to the angiogenic phenotype in a tumor model.
Neoplasms
Matrix metalloproteinase-2 mediates ribosomal RNA transcription by cleaving nucleolar histones.
Neoplasms
Matrix metalloproteinase-2 polymorphisms and clinical outcome of Chinese patients with nonsmall cell lung cancer treated with first-line, platinum-based chemotherapy.
Neoplasms
Matrix metalloproteinase-2 Promotes ?v?3 Integrin-Mediated Adhesion and Migration of Human Melanoma Cells by Cleaving Fibronectin.
Neoplasms
Matrix metalloproteinase-2 regulates vascular patterning and growth affecting tumor cell survival and invasion in GBM.
Neoplasms
Matrix metalloproteinase-2 status in stromal fibroblasts, not in tumor cells, is a significant prognostic factor in non-small-cell lung cancer.
Neoplasms
Matrix metalloproteinase-2, squamous cell carcinoma antigen, and tissue polypeptide-specific antigen expression in Egyptian patients with cervical carcinoma: Relationship with prognosis.
Neoplasms
Matrix metalloproteinase-2: A key regulator in coagulation proteases mediated human breast cancer progression through autocrine signaling.
Neoplasms
Matrix metalloproteinase-7-mediated cleavage of Fas ligand protects tumor cells from chemotherapeutic drug cytotoxicity.
Neoplasms
Matrix metalloproteinase-9 activity is associated with poor prognosis in T3-T4 node-negative colorectal cancer.
Neoplasms
Matrix metalloproteinase-9 contributes to intestinal tumourigenesis in the adenomatous polyposis coli multiple intestinal neoplasia mouse.
Neoplasms
Matrix metalloproteinase-9 expression in bladder washes from bladder cancer patients predicts pathological stage and grade.
Neoplasms
Matrix metalloproteinase-9 from bone marrow-derived cells contributes to survival but not growth of tumor cells in the lung microenvironment.
Neoplasms
Matrix Metalloproteinase-9 Is a Marker of Heart Failure After Acute Myocardial Infarction.
Neoplasms
Matrix metalloproteinase-cleavable nanocapsules for tumor-activated drug release.
Neoplasms
Matrix metalloproteinase-initiated aggregation of melanin nanoparticles as highly efficient contrast agent for enhanced tumor accumulation and dual-modal imaging.
Neoplasms
Matrix metalloproteinase-sensitive size-shrinkable nanoparticles for deep tumor penetration and pH triggered doxorubicin release.
Neoplasms
Matrix metalloproteinase-triggered denuding of engineered gold nanoparticles for selective cell uptake.
Neoplasms
Matrix metalloproteinases 2 and 9 (gelatinases A and B) expression in malignant mesothelioma and benign pleura.
Neoplasms
Matrix metalloproteinases 2 and 9 and their tissue inhibitors in low malignant potential ovarian tumors.
Neoplasms
Matrix metalloproteinases 2 and 9 immunoexpression in prostate carcinoma at the positive margin of radical prostatectomy specimens.
Neoplasms
Matrix metalloproteinases 2 and 9 in oral squamous cell carcinomas: manifestation and localization of their activity.
Neoplasms
Matrix metalloproteinases 2 and 9 in situ mRNA expression in colorectal tumors from Iraqi patients.
Neoplasms
Matrix metalloproteinases 2, 7, and 9 in tumors and sera of patients with breast cancer.
Neoplasms
Matrix metalloproteinases and E-cadherin immunoreactivity in different basal cell carcinoma histological types.
Neoplasms
Matrix Metalloproteinases and Their Tissue Inhibitors in Blood Serum of Patients with Endometrial Cancer: Clinical and Morphological Correlations.
Neoplasms
Matrix metalloproteinases and tissue inhibitors of metalloproteinases in human gliomas.
Neoplasms
Matrix metalloproteinases contribute distinct roles in neuroendocrine prostate carcinogenesis, metastasis, and angiogenesis progression.
Neoplasms
Matrix metalloproteinases in blood vessel development in human fetal skin and in cutaneous tumors.
Neoplasms
Matrix metalloproteinases in human melanoma cell lines and xenografts: increased expression of activated matrix metalloproteinase-2 (MMP-2) correlates with melanoma progression.
Neoplasms
Matrix metalloproteinases in rectal mucosa, tumour and plasma: response after preoperative irradiation.
Neoplasms
Matrix metalloproteinases may contribute compensationally to tumor invasion in T1 colorectal carcinomas.
Neoplasms
Matrix metalloproteinases play an active role in Wnt1-induced mammary tumorigenesis.
Neoplasms
Matrix metalloproteinases, their tissue inhibitors and colorectal cancer staging.
Neoplasms
Matrix metalloproteinases, tissue inhibitors of matrix metalloproteinases and angiogenic cytokines in peripheral blood of patients with thyroid cancer.
Neoplasms
Matrix metalloproteinases-2 and -9 are expressed in human neuroblastoma: contribution of stromal cells to their production and correlation with metastasis.
Neoplasms
Matrix metalloproteinases-2 and -9 in cervical cancer: different roles in tumor progression.
Neoplasms
Matrix proteases, green tea, and St. John's wort: biomedical research catches up with folk medicine.
Neoplasms
Matrix-metalloproteinases 1, 2, and 3 and their tissue inhibitors 1 and 2 in benign and malignant breast lesions: an in situ hybridization study.
Neoplasms
Matrix-metalloproteinases and their inhibitors in plasma and tumor tissue of patients with renal cell carcinoma.
Neoplasms
Matrix-metalloproteinases-2 and -9 production in bovine endometrial cell culture.
Neoplasms
May High MMP-2 and TIMP-2 Expressions Increase or Decrease the Aggressivity of Oral Cancer?
Neoplasms
MDM2 derived from dedifferentiated liposarcoma extracellular vesicles induces MMP2 production from preadipocytes.
Neoplasms
Mechanisms by which thiazolidinediones induce anti-cancer effects in cancers in digestive organs.
Neoplasms
Mediastinal Germ Cell Tumor Exhibiting a Discrepancy between Tumor Markers and Imaging: A Case Study.
Neoplasms
MEKK1 controls matrix degradation and tumor cell dissemination during metastasis of polyoma middle-T driven mammary cancer.
Neoplasms
Melanoma antigen-encoding gene-1 expression in invasive gastric carcinoma: correlation with stage of disease.
Neoplasms
Melanoma associated spongiform scleropathy: characterization, biochemical and immunohistochemical studies.
Neoplasms
Membrane type 1 matrix metalloproteinase digests interstitial collagens and other extracellular matrix macromolecules.
Neoplasms
Membrane type 1-matrix metalloproteinase (MT1-MMP) and MMP-2 immunolocalization in human prostate: change in cellular localization associated with high-grade prostatic intraepithelial neoplasia.
Neoplasms
Membrane type-1 matrix metalloproteinase stimulates tumour cell-induced platelet aggregation: role of receptor glycoproteins.
Neoplasms
Membrane-type matrix metalloproteinase (MT-MMP) gene is expressed in stromal cells of human colon, breast, and head and neck carcinomas.
Neoplasms
Membrane-type matrix metalloproteinase expression and matrix metalloproteinase-2 activation in primary human ovarian epithelial carcinoma cells.
Neoplasms
Membrane-type matrix metalloproteinase-1 expression and activation of gelatinase A as prognostic markers in advanced pediatric neuroblastoma.
Neoplasms
Membrane-type matrix metalloproteinase-1(MT1-MTP) gene is overexpressed in highly invasive hepatocellular carcinomas.
Neoplasms
MERS versus Standard Surgical Approaches for Porcine Vocal Fold Scarring with Adipose Stem Cell Constructs.
Neoplasms
Mesenchymal Stem Cells Promote Tumor Progression via Inducing Stroma Remodeling on Rabbit VX2 Bladder Tumor Model.
Neoplasms
Messenger RNA expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human hepatocellular carcinoma.
Neoplasms
Messenger RNA for two type IV collagenases is located in stromal cells in human colon cancer.
Neoplasms
Meta-analysis and meta-regression analysis of biomarkers for abdominal aortic aneurysm.
Neoplasms
Meta-analysis of association of the matrix metalloproteinase 2 (-735 C/T) polymorphism with cancer risk.
Neoplasms
Metaanalysis of the significance of matrix metalloproteinases for lymph node disease in patients with head and neck squamous cell carcinoma.
Neoplasms
Metallopeptidase, neurolysin, as a novel molecular tool for analysis of properties of cancer-producing matrix metalloproteinases-2 and -9.
Neoplasms
Metalloprotease-specific poly(ethylene glycol) methyl ether-peptide-doxorubicin conjugate for targeting anticancer drug delivery based on angiogenesis.
Neoplasms
Metalloproteinase and TIMP expression by the human breast carcinoma cell line 8701-BC.
Neoplasms
Metalloproteinase-2 expression correlates with aggressiveness of cutaneous squamous cell carcinomas.
Neoplasms
Metalloproteinase-2, -7 and -9 and tissue inhibitor of metalloproteinase-1 and -2 expression in normal, hyperplastic and neoplastic endometrium: a clinical-pathological correlation study.
Neoplasms
Metalloproteinases 2 and 9 activity during promotion and progression stages of rat liver carcinogenesis.
Neoplasms
Metalloproteinases and their inhibitors: Influence on tumor invasiveness and metastasis formation in head and neck squamous cell carcinomas.
Neoplasms
Metalloproteinases in multiple myeloma: production of matrix metalloproteinase-9 (MMP-9), activation of proMMP-2, and induction of MMP-1 by myeloma cells.
Neoplasms
METALLOPROTEINS DURING DEVELOPMENT OF WALKER-256 CARCINOSARCOMA RESISTANT PHENOTYPE.
Neoplasms
Metastasis is strongly reduced by the matrix metalloproteinase inhibitor Galardin in the MMTV-PymT transgenic breast cancer model.
Neoplasms
Metastasis of human colon tumor cells in vivo: correlation with the overexpression of plasminogen activators and 72 kDa gelatinase.
Neoplasms
Metastatic ability of MXT mouse mammary subpopulations correlates with clonal expression and/or membrane-association of gelatinase A.
Neoplasms
Metastatic and non-metastatic colorectal cancer (CRC) cells induce host metalloproteinase production in vivo.
Neoplasms
Metastatic Inhibitory and Radical Scavenging Efficacies of Saponins Extracted from the Brittle Star (Ophiocoma erinaceus).
Neoplasms
Methanol extract of Elaeagnus glabra, a Korean medicinal plant, inhibits HT1080 tumor cell invasion.
Neoplasms
Microcystin-LR promotes melanoma cell invasion and enhances matrix metalloproteinase-2/-9 expression mediated by NF-?B activation.
Neoplasms
Microenvironment effects on promoting upregulation of matrix metalloproteinases in Bcl-2-overexpressing renal cell carcinoma as a response to doxorubicin treatment inducing the production of metastasis.
Neoplasms
Microenvironment influence on human colon adenocarcinoma phenotypes and matrix metalloproteinase-2, p53 and ?-catenin tumor expressions from identical monoclonal cell tumor in the orthotopic model in athymic nude rats.
Neoplasms
Microenvironment-induced TIMP2 loss by cancer-secreted exosomal miR-4443 promotes liver metastasis of breast cancer.
Neoplasms
Microenvironment-Responsive Delivery of the Cas9 RNA-Guided Endonuclease for Efficient Genome Editing.
Neoplasms
Micronutrient synergy--a new tool in effective control of metastasis and other key mechanisms of cancer.
Neoplasms
Micropeptide CIP2A-BP encoded by LINC00665 inhibits triple-negative breast cancer progression.
Neoplasms
MicroRNA-29 Family Suppresses the Invasion of HT1080 Human Fibrosarcoma Cells by Regulating Matrix Metalloproteinase 2 Expression.
Neoplasms
MicroRNA-29a upregulates MMP2 in oral squamous cell carcinoma to promote cancer invasion and anti-apoptosis.
Neoplasms
MicroRNA-29b attenuates non-small cell lung cancer metastasis by targeting matrix metalloproteinase 2 and PTEN.
Neoplasms
MicroRNA-29b suppresses tumor angiogenesis, invasion and metastasis by regulating MMP-2 expression.
Neoplasms
microRNA-451a prevents activation of matrix metalloproteinases 2 and 9 in human cardiomyocytes during pathological stress stimulation.
Neoplasms
MicroRNA-466 (miR-466) functions as a tumor suppressor and prognostic factor in colorectal cancer (CRC).
Neoplasms
MicroRNA-495 attenuates proliferation and inflammatory response in rheumatoid arthritis fibroblast-like synoviocytes through attenuating ?-catenin pathway.
Neoplasms
MicroRNA-520a-3p suppresses non-small-cell lung carcinoma by inhibition of High Mobility Group Box 1 (HMGB1).
Neoplasms
MicroRNA-708 activation by glucocorticoid receptor agonists regulate breast cancer tumorigenesis and metastasis via downregulation of NF-?B signaling.
Neoplasms
MicroRNA-mediated extracellular matrix remodeling in squamous cell carcinoma of the oral cavity.
Neoplasms
Microsomal prostaglandin E synthase-1 in both cancer cells and hosts contributes to tumour growth, invasion and metastasis.
Neoplasms
Mid-trimester amniotic fluid pro-inflammatory biomarkers predict the risk of spontaneous preterm delivery in twins: a retrospective cohort study.
Neoplasms
Mifepristone alleviates cerebral ischemia-reperfusion injury in rats by stimulating PPAR ?.
Neoplasms
Mimicking the tumor microenvironment: Fibroblasts reduce miR-29b expression and increase the motility of ovarian cancer cells in a co-culture model.
Neoplasms
miR-135b, a key regulator of malignancy, is linked to poor prognosis in human myxoid liposarcoma.
Neoplasms
miR-143 inhibits the metastasis of pancreatic cancer and an associated signaling pathway.
Neoplasms
miR-22 Suppresses Tumor Invasion and Metastasis in Colorectal Cancer by Targeting NLRP3.
Neoplasms
miR-221/222 induces pancreatic cancer progression through the regulation of matrix metalloproteinases.
Neoplasms
miR-29b attenuates tumorigenicity and stemness maintenance in human glioblastoma multiforme by directly targeting BCL2L2.
Neoplasms
miR-29b enhances prostate cancer cell invasion independently of MMP-2 expression.
Neoplasms
miR-29b inhibits the progression of esophageal squamous cell carcinoma by targeting MMP-2.
Neoplasms
miR-768-3p is involved in the proliferation, invasion and migration of non-small cell lung carcinomas.
Neoplasms
Mitogen-activated protein kinase kinase 4 (MAP2K4) promotes human prostate cancer metastasis.
Neoplasms
Mitotic arrest induced in human DU145 prostate cancer cells in response to KHC-4 treatment.
Neoplasms
MMI-166, a selective matrix metalloproteinase inhibitor, promotes apoptosis in human pancreatic cancer.
Neoplasms
MMP inhibition blocks fibroblast-dependent skin cancer invasion, reduces vascularization and alters VEGF-A and PDGF-BB expression.
Neoplasms
MMP-1 and MMP-2 expression in uterine leiomyosarcoma and correlation with different clinicopathologic parameters.
Neoplasms
MMP-1 and MMP-2 in the cervix uteri in different steps of malignant transformation--an immunohistochemical study.
Neoplasms
MMP-19: cellular localization of a novel metalloproteinase within normal breast tissue and mammary gland tumours.
Neoplasms
MMP-2 activation and stepwise progression of pulmonary adenocarcinoma: analysis of MMP-2 and MMP-9 with gelatin zymography.
Neoplasms
MMP-2 alters VEGF expression via alphaVbeta3 integrin-mediated PI3K/AKT signaling in A549 lung cancer cells.
Neoplasms
MMP-2 and MMP-13 affect vasculogenic mimicry formation in large cell lung cancer.
Neoplasms
MMP-2 and MMP-9 as prognostic markers for the early detection of urinary bladder cancer.
Neoplasms
MMP-2 and MMP-9 expression in breast cancer-derived human fibroblasts is differentially regulated by stromal-epithelial interactions.
Neoplasms
MMP-2 and MMP-9 in normal mucosa are independently associated with outcome of colorectal cancer patients.
Neoplasms
MMP-2 and TIMP-2 expression correlates with poor prognosis in cervical carcinoma--a clinicopathologic study using immunohistochemistry and mRNA in situ hybridization.
Neoplasms
MMP-2 downregulation mediates differential regulation of cell death via ErbB-2 in glioma xenografts.
Neoplasms
MMP-2 expression associates with CA 125 and clinical course in endometrial carcinoma.
Neoplasms
MMP-2 expression in uveal melanoma: differential activation status dictated by the cellular environment.
Neoplasms
MMP-2 geno-phenotype is prognostic for colorectal cancer survival, whereas MMP-9 is not.
Neoplasms
MMP-2 mRNA Expression in Ovarian Cancer Tissues Predicts Patients' Response to Platinum-Taxane Chemotherapy.
Neoplasms
MMP-2 null mice exhibit an early onset and severe experimental autoimmune encephalomyelitis due to an increase in MMP-9 expression and activity.
Neoplasms
MMP-2 positivity and age less than 40 years increases the risk for recurrence in premenopausal patients with node-positive breast carcinoma.
Neoplasms
MMP-2 protein in invasive breast cancer and the impact of MMP-2/TIMP-2 phenotype on overall survival.
Neoplasms
MMP-2 responsive polymeric micelles for cancer-targeted intracellular drug delivery.
Neoplasms
MMP-2 sensitive poly(malic acid) micelles stabilized by ?-? stacking enable high drug loading capacity.
Neoplasms
MMP-2 siRNA induced Fas/CD95-mediated extrinsic II apoptotic pathway in the A549 lung adenocarcinoma cell line.
Neoplasms
MMP-2, MMP-9 and activin A blood levels in patients with breast cancer or prostate cancer metastatic to the bone.
Neoplasms
MMP-2-Controlled Transforming Micelles for Heterogeneic Targeting and Programmable Cancer Therapy.
Neoplasms
MMP-2-responsive fluorescent nanoprobes for enhanced selectivity of tumor cell uptake and imaging.
Neoplasms
MMP-2-Sensitive HA End-Conjugated Poly(amidoamine) Dendrimers via Click Reaction To Enhance Drug Penetration into Solid Tumor.
Neoplasms
MMP-9 activation by tumor trypsin-2 enhances in vivo invasion of human tongue carcinoma cells.
Neoplasms
MMP-9 and MMP-2 gelatinases and TIMP-1 and TIMP-2 inhibitors in breast cancer: correlations with prognostic factors.
Neoplasms
MMP-9 from sublethally irradiated tumor promotes Lewis lung carcinoma cell invasiveness and pulmonary metastasis.
Neoplasms
MMP-9 secretion and MMP-2 activation distinguish invasive and metastatic sublines of a mouse mammary carcinoma system showing epithelial-mesenchymal transition traits.
Neoplasms
MMP-responsive theranostic nanoplatform based on mesoporous silica nanoparticles for tumor imaging and targeted drug delivery.
Neoplasms
Modulation of airway remodeling-associated mediators by the antifibrotic compound, pirfenidone, and the matrix metalloproteinase inhibitor, batimastat, during acute lung injury in mice.
Neoplasms
Modulation of cell growth and matrix metalloproteinase-2 activation of oral squamous cell carcinoma as a function of culture condition with type I collagen.
Neoplasms
Modulation of MMP-2 and MMP-9 by cytokines, mitogens and inhibitors in lung cancer and malignant mesothelioma cell lines.
Neoplasms
Modulation of MMP-2 and MMP-9 secretion by cytokines, inducers and inhibitors in human glioblastoma T-98G cells.
Neoplasms
Modulation of type IV collagenase and plasminogen activator in a hamster fibrosarcoma by basement membrane components and lung fibroblasts.
Neoplasms
Moesin Up-regulation Is Associated with Enhanced Tumor Progression Imaged Non-invasively in an Orthotopic Mouse Model of Human Glioblastoma.
Neoplasms
Molecular basis for the involvement of thymidine phosphorylase in cancer invasion.
Neoplasms
Molecular characterization and clinical implications of spindle cells in nasopharyngeal carcinoma: a novel molecule-morphology model of tumor progression proposed.
Neoplasms
Molecular characterization and in-silico analysis of the tissue inhibitor of metalloproteinases-3 (TIMP-3) gene of canine mammary tumor.
Neoplasms
Molecular cloning of murine 72-kDa type IV collagenase and its expression during mouse development.
Neoplasms
Molecular Decision Tree Algorithms Predict Individual Recurrence Pattern for Locally Advanced Nasopharyngeal Carcinoma.
Neoplasms
Molecular docking and inhibition of matrix metalloproteinase-2 by novel difluorinatedbenzylidene curcumin analog.
Neoplasms
Molecular dynamics simulations of metalloproteinases types 2 and 3 reveal differences in the dynamic behavior of the S1' binding pocket.
Neoplasms
Molecular mechanism about lymphogenous metastasis of hepatocarcinoma cells in mice.
Neoplasms
Molecular mechanisms behind the biological effects of hesperidin and hesperetin for the prevention of cancer and cardiovascular diseases.
Neoplasms
Molecular prognostic markers in recurrent and in non-recurrent epithelial ovarian cancer.
Neoplasms
Monascus purpureus-fermented rice inhibits tumor necrosis factor-?-induced upregulation of matrix metalloproteinase 2 and 9 in human aortic smooth muscle cells.
Neoplasms
Monoclonal antibodies to type IV collagenase recognize a protein with limited sequence homology to interstitial collagenase and stromelysin.
Neoplasms
Monomeric 55-kDa guanidinobenzoatase switches to a serine proteinase activity upon tetramerization. Tetrameric proteinase SP 220 K appears as the native form.
Neoplasms
Monomethyl selenium--specific inhibition of MMP-2 and VEGF expression: implications for angiogenic switch regulation.
Neoplasms
Morusin Suppresses Cancer Cell Invasion and MMP-2 Expression through ERK Signaling in Human Nasopharyngeal Carcinoma.
Neoplasms
Mr 92,000 gelatinase release correlates with the metastatic phenotype in transformed rat embryo cells.
Neoplasms
mRNA concentrations of MIF in subcutaneous abdominal adipose cells are associated with adipocyte size and insulin action.
Neoplasms
mRNA expression of matrix metalloproteases and their inhibitors differs in subtypes of renal cell carcinomas.
Neoplasms
MS-275 sensitizes TRAIL-resistant breast cancer cells, inhibits angiogenesis and metastasis, and reverses epithelial-mesenchymal transition in vivo.
Neoplasms
MSH6 Aggravates the Hypoxic Microenvironment via Regulating HIF1A to Promote the Metastasis of Glioblastoma Multiforme.
Neoplasms
MT1-MMP and MMP-2 mRNA expression in human ovarian tumors: possible implications for the role of desmoplastic fibroblasts.
Neoplasms
MT1-MMP expression promotes tumor growth and angiogenesis through an up-regulation of vascular endothelial growth factor expression.
Neoplasms
MT1-MMP initiates activation of pro-MMP-2 and integrin alphavbeta3 promotes maturation of MMP-2 in breast carcinoma cells.
Neoplasms
Multi-Förster Resonance Energy Transfer-Based Fluorescent Probe for Spatiotemporal Matrix Metalloproteinase-2 and Caspase-3 Imaging.
Neoplasms
Multi-layered nanogels with MMP-sheddable PEG masks: Preparation and promotion of tumor cell uptake by controlling surface characteristics.
Neoplasms
Multi-layered proteogenomic analysis unravels cancer metastasis directed by MMP-2 and focal adhesion kinase signaling.
Neoplasms
Multifunctional role of VIP in prostate cancer progression in a xenograft model: Suppression by curcumin and COX-2 inhibitor NS-398.
Neoplasms
Multifunctional Self-Assembling Peptide-Based Nanostructures for Targeted Intracellular Delivery: Design, Physicochemical Characterization, and Biological Assessment.
Neoplasms
Multiparametric in situ messenger RNA hybridization analysis to detect metastasis-related genes in surgical specimens of human colon carcinomas.
Neoplasms
Multiparametric in situ mRNA hybridization analysis of gastric biopsies predicts lymph node metastasis in patients with gastric carcinoma.
Neoplasms
Multiparametric in situ mRNA hybridization analysis to predict disease recurrence in patients with colon carcinoma.
Neoplasms
Multiple molecular modelling studies on some derivatives and analogues of glutamic acid as matrix metalloproteinase-2 inhibitors.
Neoplasms
Multiplex Cytokine Analysis of Aqueous Humor in Juvenile Idiopathic Arthritis-Associated Anterior Uveitis With or Without Secondary Glaucoma.
Neoplasms
Multistage-responsive nanovehicle to improve tumor penetration for dual-modality imaging-guided photodynamic-immunotherapy.
Neoplasms
Mutation analysis of tumor suppressor gene PTEN in patients with gastric carcinomas and its impact on PI3K/AKT pathway.
Neoplasms
N-Acetylglucosaminyltransferase V triggers overexpression of MT1-MMP and reinforces the invasive/metastatic potential of cancer cells.
Neoplasms
N-Myc down regulation induced differentiation, early cell cycle exit, and apoptosis in human malignant neuroblastoma cells having wild type or mutant p53.
Neoplasms
N-O-Isopropyl Sulfonamido-Based Hydroxamates as Matrix Metalloproteinase Inhibitors: Hit Selection and in Vivo Antiangiogenic Activity.
Neoplasms
Nanoparticle-mediated local depletion of tumour-associated platelets disrupts vascular barriers and augments drug accumulation in tumours.
Neoplasms
NaoXinTong Inhibits the Advanced Atherosclerosis and Enhances the Plaque Stability in Apolipoprotein E Deficient Mice.
Neoplasms
Natural products as a gold mine for selective matrix metalloproteinases inhibitors.
Neoplasms
Near-infrared triple-helical peptide with quenched fluorophores for optical imaging of MMP-2 and MMP-9 proteolytic activity in vivo.
Neoplasms
Near-Infrared-Activated Fluorescence Resonance Energy Transfer-Based Nanocomposite to Sense MMP2-Overexpressing Oral Cancer Cells.
Neoplasms
NEDD9/Arf6-dependent endocytic trafficking of matrix metalloproteinase 14: a novel mechanism for blocking mesenchymal cell invasion and metastasis of breast cancer.
Neoplasms
Nestin suppression attenuates invasive potential of endometrial cancer cells by downregulating TGF-? signaling pathway.
Neoplasms
Neutralization of MMP-2 and TNFR1 Regulates the Severity of S. aureus-Induced Septic Arthritis by Differential Alteration of Local and Systemic Proinflammatory Cytokines in Mice.
Neoplasms
Neutrophil elastase processing of gelatinase A is mediated by extracellular matrix.
Neoplasms
Neutrophil-derived serine proteinases enhance membrane type-1 matrix metalloproteinase-dependent tumor cell invasion.
Neoplasms
New clinical scoring system for prognosis of early recurrence of colorectal liver metastases after surgical treatment.
Neoplasms
New enzyme-activated solubility-switchable contrast agent for magnetic resonance imaging: from synthesis to in vivo imaging.
Neoplasms
New facets of matrix metalloproteinases MMP-2 and MMP-9 as cell surface transducers: Outside-in signaling and relationship to tumor progression.
Neoplasms
New Insights on Old Biomarkers Involved in Tumor Microenvironment Changes and Their Diagnostic Relevance in Non-Small Cell Lung Carcinoma.
Neoplasms
New pathway links from cancer-progression determinants to gene expression of matrix metalloproteinases in breast cancer cells.
Neoplasms
New radioiodinated carboxylic and hydroxamic matrix metalloproteinase inhibitor tracers as potential tumor imaging agents.
Neoplasms
Newt squamous carcinoma proves phylogenetic conservation of tumors as caricatures of tissue renewal.
Neoplasms
Nifuroxazide induces apoptosis and impairs pulmonary metastasis in breast cancer model.
Neoplasms
NIK- and IKK?-binding protein promotes colon cancer metastasis by activating the classical NF-?B pathway and MMPs.
Neoplasms
No correlation between TIMP2 -418 G>C polymorphism and increased risk of cancer: evidence from a meta-analysis.
Neoplasms
Non-thermal atmospheric pressure plasmas as a novel candidate for preventive therapy of melanoma.
Neoplasms
Norepinephrine up-regulates the expression of vascular endothelial growth factor, matrix metalloproteinase (MMP)-2, and MMP-9 in nasopharyngeal carcinoma tumor cells.
Neoplasms
Norepinephrine-induced invasion by pancreatic cancer cells is inhibited by propranolol.
Neoplasms
Normal nonmetastatic human trophoblast cells share in vitro invasive properties of malignant cells.
Neoplasms
Normalization of the tumor microenvironment: evidence for tissue inhibitor of metalloproteinase-2 as a cancer therapeutic.
Neoplasms
Novel and therapeutic effect of caffeic acid and caffeic acid phenyl ester on hepatocarcinoma cells: complete regression of hepatoma growth and metastasis by dual mechanism.
Neoplasms
Novel chalcone derivatives as hypoxia-inducible factor (HIF)-1 inhibitor: synthesis, anti-invasive and anti-angiogenic properties.
Neoplasms
Novel roles of androgen receptor, epidermal growth factor receptor, TP53, regulatory RNAs, NF-kappa-B, chromosomal translocations, neutrophil associated gelatinase, and matrix metalloproteinase-9 in prostate cancer and prostate cancer stem cells.
Neoplasms
Novel solubility-switchable MRI agent allows the noninvasive detection of matrix metalloproteinase-2 activity in vivo in a mouse model.
Neoplasms
Novel ternary vanadium-betaine-peroxido species suppresses H-ras and matrix metalloproteinase-2 expression by increasing reactive oxygen species-mediated apoptosis in cancer cells.
Neoplasms
Nuclear factor E2-related factor 2 knockdown enhances glucose uptake and alters glucose metabolism in AML12 hepatocytes.
Neoplasms
Nuclear Localization of PTTG1 Promotes Migration and Invasion of Seminoma Tumor through Activation of MMP-2.
Neoplasms
Nucleophosmin Mutants Promote Adhesion, Migration and Invasion of Human Leukemia THP-1 Cells through MMPs Up-regulation via Ras/ERK MAPK Signaling.
Neoplasms
Nutrient sensor O-GlcNAc transferase regulates breast cancer tumorigenesis through targeting of the oncogenic transcription factor FoxM1.
Neoplasms
Occurrence of an active form of gelatinase in human gastric and colorectal carcinoma tissues.
Neoplasms
Ocimum gratissimum retards breast cancer growth and progression and is a natural inhibitor of matrix metalloproteases.
Neoplasms
Oct-3/4 expression reflects tumor progression and regulates motility of bladder cancer cells.
Neoplasms
Olea europaea leaf extract and bevacizumab synergistically exhibit beneficial efficacy upon human glioblastoma cancer stem cells through reducing angiogenesis and invasion in vitro.
Neoplasms
Olive Leaf Extract and Its Main Component Oleuropein Prevent Chronic Ultraviolet B Radiation-Induced Skin Damage and Carcinogenesis in Hairless Mice.
Neoplasms
Olmesartan decreases IL-1? and TNF-? levels; downregulates MMP-2, MMP-9, COX-2, and RANKL; and upregulates OPG in experimental periodontitis.
Neoplasms
Oncogenic transformation of human benign prostate hyperplasia with chronic cadmium exposure.
Neoplasms
Oncostatin M promotes STAT3 activation, VEGF production, and invasion in osteosarcoma cell lines.
Neoplasms
Opposite Roles of CCR2 and CX3CR1 Macrophages in Alkali-Induced Corneal Neovascularization.
Neoplasms
Optical imaging of matrix metalloproteinase-2 activity in tumors: feasibility study in a mouse model.
Neoplasms
Optical imaging of MMP expression and cancer progression in an inflammation-induced colon cancer model.
Neoplasms
Oral and IV Dosages of Doxorubicin-Methotrexate loaded- Nanoparticles Inhibit Progression of Oral Cancer by Down- Regulation of Matrix Methaloproteinase 2 Expression in Vivo.
Neoplasms
Organ heterogeneity of host-derived matrix metalloproteinase expression and its involvement in multiple-organ metastasis by lung cancer cell lines.
Neoplasms
Ornithine decarboxylase, mitogen-activated protein kinase and matrix metalloproteinase-2 expressions in human colon tumors.
Neoplasms
Osteopontin alters endothelial and valvular interstitial cell behaviour in calcific aortic valve stenosis through HMGB1 regulation.
Neoplasms
Osteopontin induces nuclear factor kappa B-mediated promatrix metalloproteinase-2 activation through I kappa B alpha /IKK signaling pathways, and curcumin (diferulolylmethane) down-regulates these pathways.
Neoplasms
Osteopontin is linked to p65 and MMP-9 expression in pulmonary adenocarcinoma but not in malignant pleural mesothelioma.
Neoplasms
Osteopontin stimulates tumor growth and activation of promatrix metalloproteinase-2 through nuclear factor-kappa B-mediated induction of membrane type 1 matrix metalloproteinase in murine melanoma cells.
Neoplasms
Osteopontin: it's role in regulation of cell motility and nuclear factor kappa B-mediated urokinase type plasminogen activator expression.
Neoplasms
Outline of gelatinase inhibitors as anti-cancer agents: A patent mini-review for 2010-present.
Neoplasms
Ovarian aging-like phenotype in the hyperandrogenism-induced murine model of polycystic ovary.
Neoplasms
Ovarian carcinoma cells in serous effusions show altered MMP-2 and TIMP-2 mRNA levels.
Neoplasms
Overcoming Intrinsic Doxorubicin Resistance in Melanoma by Anti-Angiogenic and Anti-Metastatic Effects of Liposomal Prednisolone Phosphate on Tumor Microenvironment.
Neoplasms
Overexpression level of stromelysin 3 is related to the lymph node involvement in non-small cell lung cancer.
Neoplasms
Overexpression of Aurora-A enhances invasion and matrix metalloproteinase-2 expression in esophageal squamous cell carcinoma cells.
Neoplasms
Overexpression of interleukin-1beta in the murine pancreas results in chronic pancreatitis.
Neoplasms
Overexpression of matrix metalloproteinase 2 predicts unfavorable outcome in early-stage non-small cell lung cancer.
Neoplasms
Overexpression of matrix metalloproteinase-1 and -9 mRNA is associated with progression of oral dysplasia to cancer.
Neoplasms
Overexpression of matrix metalloproteinase-7 and -9 in NSCLC tumor and stromal cells: Correlation with a favorable clinical outcome.
Neoplasms
Overexpression of matrix-metalloproteinase-9 in human breast cancer: a potential favourable indicator in node-negative patients.
Neoplasms
Overexpression of micro ribonucleic acid-591 inhibits cell proliferation and invasion of malignant pleural mesothelioma cells.
Neoplasms
Overexpression of MMP-2 in laryngeal squamous cell carcinoma: a potential indicator for poor prognosis.
Neoplasms
Overexpression of MMP-9 correlates with growth of small hepatocellular carcinoma.
Neoplasms
Overexpression of MT3-MMP in hepatocellular carcinoma correlates with capsular invasion.
Neoplasms
Overexpression of phospholipase D enhances matrix metalloproteinase-2 expression and glioma cell invasion via protein kinase C and protein kinase A/NF-kappaB/Sp1-mediated signaling pathways.
Neoplasms
Overexpression of protein kinase C-alpha and -beta isozymes by stromal dendritic cells in basal and squamous cell carcinoma.
Neoplasms
Oxalomalate suppresses metastatic melanoma through IDH-targeted stress response to ROS.
Neoplasms
Oxymatrine alleviates periodontitis in rats by inhibiting inflammatory factor secretion and regulating MMPs/TIMP protein expression1.
Neoplasms
p16 inhibits matrix metalloproteinase-2 expression via suppression of Sp1-mediated gene transcription.
Neoplasms
p16(INK4A) Represses the paracrine tumor-promoting effects of breast stromal fibroblasts.
Neoplasms
p202, an interferon-inducible protein, mediates multiple antitumor activities in human pancreatic cancer xenograft models.
Neoplasms
p37 from Mycoplasma hyorhinis promotes cancer cell invasiveness and metastasis through activation of MMP-2 and followed by phosphorylation of EGFR.
Neoplasms
p38 kinase is a key signaling molecule for H-Ras-induced cell motility and invasive phenotype in human breast epithelial cells.
Neoplasms
P53 stratification reveals the prognostic utility of matrix metalloproteinase-9 protein expression in glioblastoma.
Neoplasms
Palmatine inhibits TRIF-dependent NF-?B pathway against inflammation induced by LPS in goat endometrial epithelial cells.
Neoplasms
Pancreatic stellate cells are an important source of MMP-2 in human pancreatic cancer and accelerate tumor progression in a murine xenograft model and CAM assay.
Neoplasms
Paradoxical antiproliferative effect by a murine mammary tumor-derived epithelial cell line.
Neoplasms
Partial purification of gelatinases and effect of anti-inflammatory drugs on the tumor necrosis factor-stimulated production of active gelatinase by granulation tissue in culture.
Neoplasms
Pathological and prognostic significance of matrix metalloproteinase-2 expression in ovarian cancer: a meta-analysis.
Neoplasms
Pathological function of prostaglandin E2 receptors in transitional cell carcinoma of the upper urinary tract.
Neoplasms
Patients with hepatic breast cancer metastases demonstrate highly specific profiles of matrix metalloproteinases MMP-2 and MMP-9 after SIRT treatment as compared to other primary and secondary liver tumours.
Neoplasms
Pattern of collagen fibers and localization of matrix metalloproteinase 2 and 9 during breast cancer invasion.
Neoplasms
Pattern of expression of inflammatory markers in adipose tissue of untreated hypertensive patients.
Neoplasms
PD-1 Blockade for Improving the Antitumor Efficiency of Polymer-Doxorubicin Nanoprodrug.
Neoplasms
Pediatric adrenocortical tumors: morphological diagnostic criteria and immunohistochemical expression of matrix metalloproteinase type 2 and human leucocyte-associated antigen (HLA) class II antigens Results from the Italian Pediatric Rare Tumor (TREP) Study project.
Neoplasms
PEG10 plays a crucial role in human lung cancer proliferation, progression, prognosis and metastasis.
Neoplasms
PEGylated Cationic Vectors Containing a Protease-Sensitive Peptide as a miRNA Delivery System for Treating Breast Cancer.
Neoplasms
PEGylation extends circulation half-life while preserving in vitro and in vivo activity of tissue inhibitor of metalloproteinases-1 (TIMP-1).
Neoplasms
Peptide mediated active targeting and intelligent particle size reduction-mediated enhanced penetrating of fabricated nanoparticles for triple-negative breast cancer treatment.
Neoplasms
Performance of a new fluorescence-labeled MMP inhibitor to image tumor MMP activity in vivo in comparison to an MMP-activatable probe.
Neoplasms
Periodontitis and Endothelial Dysfunction: Periodontal Clinical Parameters and Levels of Salivary Markers Interleukin-1?, Tumor Necrosis Factor-?, Matrix Metalloproteinase-2, Tissue Inhibitor of Metalloproteinases-2 Complex, and Nitric Oxide.
Neoplasms
Periodontitis and type 2 diabetes among women with previous gestational diabetes: epidemiological and immunological aspects in a follow-up of three years.
Neoplasms
Peritumoral Clefting and Expression of MMP-2 and MMP-9 in Basal Cell Carcinoma of the Skin.
Neoplasms
Phase I and pharmacologic study of the specific matrix metalloproteinase inhibitor BAY 12-9566 on a protracted oral daily dosing schedule in patients with solid malignancies.
Neoplasms
Phase I and pharmacological study of the oral matrix metalloproteinase inhibitor, MMI270 (CGS27023A), in patients with advanced solid cancer.
Neoplasms
Phase I study of low-dose metronomic temozolomide for recurrent malignant gliomas.
Neoplasms
Phorbol ester tumour promoter mediated altered expression and regulation of matrix metalloproteinase-2 in a H-ras transformed cell line capable of benign tumour formation.
Neoplasms
Phosphoinositide 3-kinase regulates membrane Type 1-matrix metalloproteinase (MMP) and MMP-2 activity during melanoma cell vasculogenic mimicry.
Neoplasms
Phosphorylated hepatocyte growth factor receptor/c-Met is associated with tumor growth and prognosis in patients with bladder cancer: correlation with matrix metalloproteinase-2 and -7 and E-cadherin.
Neoplasms
Photodynamic effect in medulloblastoma: downregulation of matrix metalloproteinases and human telomerase reverse transcriptase expressions.
Neoplasms
Photodynamic effects on nasopharyngeal carcinoma (NPC) cells with 5-aminolevulinic acid or its hexyl ester.
Neoplasms
Photodynamic Molecular Beacons triggered by MMP-2 and MMP-9: Influence of the distance between photosensitizer and quencher onto photophysical properties and enzymatic activation.
Neoplasms
Photothermal/matrix metalloproteinase-2 dual-responsive gelatin nanoparticles for breast cancer treatment.
Neoplasms
Pigment epithelium-derived factor upregulates collagen I and downregulates matrix metalloproteinase 2 in osteosarcoma cells, and colocalises to collagen I and heat shock protein 47 in fetal and adult bone.
Neoplasms
Pitavastatin inhibits hepatic steatosis and fibrosis in non-alcoholic steatohepatitis model rats.
Neoplasms
Plantamajoside, a potential anti-tumor herbal medicine inhibits breast cancer growth and pulmonary metastasis by decreasing the activity of matrix metalloproteinase-9 and -2.
Neoplasms
Plasma levels and diagnostic utility of VEGF, MMP-2 and TIMP-2 in the diagnostics of breast cancer patients.
Neoplasms
Plasma Levels of Inflammatory Biomarkers in Peripheral Arterial Disease: Results of a Cohort Study.
Neoplasms
Plasma levels of matrix metalloproteinases 2 and 9 correlate with histological grade in breast cancer patients.
Neoplasms
Plasma matrix metalloproteinase 9 as biomarker of prostate cancer progression in Dunning (Copenhagen) rats.
Neoplasms
Plasma matrix metalloproteinases, cytokines and angiogenic factors in moyamoya disease.
Neoplasms
Plasma membrane-dependent activation of gelatinase A in human vascular endothelial cells.
Neoplasms
Plasma MMP-2 and MMP-7 levels are elevated first month after surgery and may promote growth of residual metastases.
Neoplasms
Plasmatic level of neuroinflammatory markers predict the extent of diffusion-weighted image lesions in hyperacute stroke.
Neoplasms
Plasminogen activator activities in short-term tissue cultures of benign prostatic hyperplasia and prostatic carcinoma.
Neoplasms
Plasminogen Activator Inhibitor-2 Plays a Leading Prognostic Role among Protease Families in Non-Small Cell Lung Cancer.
Neoplasms
Platelet-derived microparticles promote invasiveness of prostate cancer cells via upregulation of MMP-2 production.
Neoplasms
Pleural fluids associated with metastatic lung tumors are rich in progelatinase B/proMMP-9.
Neoplasms
Polymorphism in the Matrix Metalloproteinase-2 Gene Promoter is Associated with Cervical Neoplasm Risk in Mexican Women.
Neoplasms
Polymorphism of MMP-9 gene is not associated with the risk of urinary cancers: Evidence from an updated meta-analysis.
Neoplasms
Polymorphisms in MMP-1, MMP-2, MMP-7, MMP-13 and MT2A do not contribute to breast, lung and colon cancer risk in polish population.
Neoplasms
Polyphenols from Artemisia annua L Inhibit Adhesion and EMT of Highly Metastatic Breast Cancer Cells MDA-MB-231.
Neoplasms
Porf-2 Inhibits Tumor Cell Migration Through the MMP-2/9 Signaling Pathway in Neuroblastoma and Glioma.
Neoplasms
Positive and negative transcriptional elements of the human type IV collagenase gene.
Neoplasms
Positive correlation between inhibitors of matrix metalloproteinase 1 and matrix metalloproteinases in malignant ovarian tumor tissues.
Neoplasms
Possible in vivo mechanisms involved in photodynamic therapy using tetrapyrrolic macrocycles.
Neoplasms
Possible role of matrix metalloproteinases (MMPs) in hyperostosis of intracranial meningiomas.
Neoplasms
Post-translational activation of Mmp2 correlates with patterns of active collagen degradation during the development of the zebrafish tail.
Neoplasms
Posttranscriptional stimulation of endothelial cell matrix metalloproteinases 2 and 1 by endothelioma cells.
Neoplasms
Potent anti-cancer effects of citrus peel flavonoids in human prostate xenograft tumors.
Neoplasms
Potent delivery of an MMP inhibitor to the tumor microenvironment with thermosensitive liposomes for the suppression of metastasis and angiogenesis.
Neoplasms
Potent tumor targeting drug release system comprising MMP-2 specific peptide fragment with self-assembling characteristics.
Neoplasms
Potential MMP2-mediated availability of HLA binding, mutant ECM peptides reflects better melanoma survival rates and greater T-cell infiltrates.
Neoplasms
Potential Role of Fibroblast-Like Synoviocytes in Joint Damage Induced by Brucella abortus Infection through Production and Induction of Matrix Metalloproteinases.
Neoplasms
Potential role of M2 TAMs around lymphatic vessels during lymphatic invasion in papillary thyroid carcinoma.
Neoplasms
Potential urinary monitoring of the enhanced permeability and retention effect using MMP-2-responsive poly(ethylene glycol) derivatives.
Neoplasms
Potentiation of scutellarin on human tongue carcinoma xenograft by low-intensity ultrasound.
Neoplasms
POU5F1 enhances the invasiveness of cancer stem-like cells in lung adenocarcinoma by upregulation of MMP-2 expression.
Neoplasms
PPAR? delivered by Ch-GNPs onto titanium surfaces inhibits implant-induced inflammation and induces bone mineralization of MC-3T3E1 osteoblast-like cells.
Neoplasms
PPAR? regulates inflammatory reaction by inhibiting the MAPK/NF-?B pathway in C2C12 skeletal muscle cells.
Neoplasms
PPARalpha downregulates airway inflammation induced by lipopolysaccharide in the mouse.
Neoplasms
Predicting high-risk human papillomavirus infection, progression of cervical intraepithelial neoplasia, and prognosis of cervical cancer with a panel of 13 biomarkers tested in multivariate modeling.
Neoplasms
Predicting Novel Antitumor Agents: 3D-Pharmacophore Mapping of ?-N-biaryl Ether Sulfonamide-Based Hydroxamates as Potentially MMP-2 Inhibitors.
Neoplasms
Prediction of healing progress of pressure ulcers by distribution analysis of protein markers on necrotic tissue: A retrospective cohort study.
Neoplasms
Prediction of prognosis in gallbladder carcinoma by CD147 and MMP-2 immunohistochemistry.
Neoplasms
Predictive value of lymph node and tumor matrix metalloproteinase expression in the analysis of metastatic periampullary tumors.
Neoplasms
Predictors of exacerbations in chronic obstructive pulmonary disease--results from the Bergen COPD cohort study.
Neoplasms
Preference of Aerosolized Pirfenidone to Oral Intake: An Experimental Model of Pulmonary Fibrosis by Paraquat.
Neoplasms
Preferential digestion of basement membrane collagen by an enzyme derived from a metastatic murine tumor.
Neoplasms
Preliminary evaluation of inhibition of matrix-metalloprotease MMP-2 and MMP-9 by Passiflora edulis and P foetida aqueous extracts.
Neoplasms
Preoperative radiotherapy and extracellular matrix remodeling in rectal mucosa and tumour matrix metalloproteinases and plasminogen components.
Neoplasms
Preoperative Serum Levels of Matrix Metalloproteinase-2 (MMP-2) and Survival of Breast Cancer among Korean Women.
Neoplasms
Preparation and characterization of a novel chimeric protein VEGI-CTT in Escherichia coli.
Neoplasms
Presence of active gelatinases in endometrial carcinoma and correlation of matrix metalloproteinase expression with increasing tumor grade and invasion.
Neoplasms
Presence of high levels of MT1-MMP protein in fibroblastic cells of human invasive carcinomas.
Neoplasms
Presence of Myofibroblasts and Expression of Matrix Metalloproteinase-2 (MMP-2) in Ameloblastomas Correlate with Rupture of the Osseous Cortical.
Neoplasms
Prevalence of vascular-endothelial growth factor, matrix metalloproteinases and tissue inhibitors of metalloproteinases in primary breast cancer.
Neoplasms
Primary breast myoepithelial cells exert an invasion-suppressor effect on breast cancer cells via paracrine down-regulation of MMP expression in fibroblasts and tumour cells.
Neoplasms
Primary Ovarian Tumors With Lymphogenic and Hematogenic Metastasis Express High MMP-14, Which Colocalizes With Highly Sulfated Chondroitin Sulfate in the Stroma.
Neoplasms
Pro-matrix metalloproteinase-2 transfection increases orthotopic primary growth and experimental metastasis of MDA-MB-231 human breast cancer cells in nude mice.
Neoplasms
Probing the S1' Site for the Identification of Non-Zinc-Binding MMP-2 Inhibitors.
Neoplasms
Production of bioengineered cancer tissue constructs in vitro: epithelium-mesenchyme heterotypic interactions.
Neoplasms
Production of extracellular matrix-degrading proteinases by primary cultures of human epithelial ovarian carcinoma cells.
Neoplasms
Production of matrix metalloproteinase-2 and metalloproteinase-3 related to malignant behavior of esophageal carcinoma. A clinicopathologic study.
Neoplasms
Profiling of matrix metalloproteinases and tissue inhibitors of metalloproteinases proteins in bladder urothelial carcinoma.
Neoplasms
Progelatinase A mRNA expression in cell lines derived from tumors in patients with metastatic renal cell carcinoma correlates inversely with survival.
Neoplasms
Progesterone and 1,25-dihydroxyvitamin D? inhibit endometrial cancer cell growth by upregulating semaphorin 3B and semaphorin 3F.
Neoplasms
Prognostic analysis of clinicopathologic factors in 49 patients with diffuse malignant peritoneal mesothelioma treated with cytoreductive surgery and intraperitoneal hyperthermic perfusion.
Neoplasms
Prognostic and diagnostic implications of MMP-2, MMP-9, and VEGF-? expressions in colorectal cancer.
Neoplasms
Prognostic factors in papillary thyroid cancer: an evaluation of 601 consecutive patients.
Neoplasms
Prognostic relevance of serum levels of the angiogenic peptide bFGF in advanced carcinoma of the head and neck treated by primary radiochemotherapy.
Neoplasms
Prognostic significance of circulating matrix metalloproteinase-2 to tissue inhibitor of metalloproteinases-2 ratio in recurrence of urothelial cancer after complete resection.
Neoplasms
Prognostic Significance of Ets-1 and the Matrix Metalloproteinase-2 to Tissue Inhibitor of Matrix Metalloproteinase-2 Ratio in Egyptian Epithelial Ovarian Cancer Patients.
Neoplasms
Prognostic significance of extracellular matrix degrading enzymes-cathepsin L and matrix metalloproteases-2 [MMP-2] in human pancreatic cancer.
Neoplasms
Prognostic Significance of Extracellular Matrix Metalloproteinase Inducer and Matrix Metalloproteinase 2 in Epithelial Ovarian Cancer.
Neoplasms
Prognostic significance of matrix metalloproteinase-2 in gynecological cancer: a systemic review of the literature and meta-analysis.
Neoplasms
Prognostic significance of matrix metalloproteinase-2, -8, -9, and -13 in oral tongue cancer.
Neoplasms
Prognostic significance of matrix metalloproteinases 2 and 9 in endometrial cancer.
Neoplasms
Prognostic significance of matrix metalloproteinases-2 activation ratio in renal cell carcinoma.
Neoplasms
Prognostic significance of phosphorylated signal transducer and activator of transcription 3 and suppressor of cytokine signaling 3 expression in human cutaneous melanoma.
Neoplasms
Prognostic significance of plasma matrix metalloprotease-2 in pancreatic cancer patients.
Neoplasms
Prognostic significance of stromal metalloproteinase-2 in ovarian adenocarcinoma and its relation to carcinoma progression.
Neoplasms
Prognostic significance of the expression of nuclear eukaryotic translation initiation factor 5A2 in human melanoma.
Neoplasms
Prognostic significance of the immunoexpression of matrix metalloproteinase MMP2 and its inhibitor TIMP2 in laryngeal cancer.
Neoplasms
Prognostic value of matrix metalloproteinase-2 (MMP-2) expression in endometrial endometrioid adenocarcinoma.
Neoplasms
Prognostic value of matrix metalloproteinase-2 (MMP-2), matrix metalloproteinase-9 (MMP-9) and aminopeptidase N/CD13 in breast cancer patients.
Neoplasms
Prognostic value of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in bladder carcinoma.
Neoplasms
Prognostic value of matrix metalloproteinases (MMP-2 and MMP-9) in patients with lymph node-negative breast carcinoma.
Neoplasms
Prognostic value of membrane type 1 and 2 matrix metalloproteinase expression and gelatinase A activity in bladder cancer.
Neoplasms
Prognostic value of MMP-2 for patients with ovarian epithelial carcinoma: a systematic review and meta-analysis.
Neoplasms
Prognostic value of MMP-2 immunoreactive protein (72 kD type IV collagenase) in primary skin melanoma.
Neoplasms
Prognostic value of MMP-2, -9 and TIMP-1,-2 immunoreactive protein at the invasive front in advanced head and neck squamous cell carcinomas.
Neoplasms
Prognostic value of tumor progression-related gene expression in colorectal cancer patients.
Neoplasms
Prognostic values of ETS-1, MMP-2 and MMP-9 expression and co-expression in breast cancer patients.
Neoplasms
Prognostic values of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 expression in bladder cancer.
Neoplasms
Programmed drug delivery system based on optimized "size decrease and hydrophilicity/hydrophobicity transformation" for enhanced hepatocellular carcinoma therapy of doxorubicin.
Neoplasms
Programmed packaging of mesoporous silica nanocarriers for matrix metalloprotease 2-triggered tumor targeting and release.
Neoplasms
Progression elevated gene-3 (PEG-3) induces pleiotropic effects on tumor progression: modulation of genomic stability and invasion.
Neoplasms
Progression of mycosis fungoides is associated with changes in angiogenesis and expression of the matrix metalloproteinases 2 and 9.
Neoplasms
Progression of non-small cell lung cancer: diagnostic and prognostic utility of matrix metalloproteinase-2, C-reactive protein and serum amyloid A.
Neoplasms
Progressive upregulation of metastasis-related genes in human colon cancer cells implanted into the cecum of nude mice.
Neoplasms
Prolonged butyrate treatment inhibits the migration and invasion potential of HT1080 tumor cells.
Neoplasms
Prominent expression of metalloproteinases in early stages of ovarian tumorigenesis.
Neoplasms
Propionibacterium acnes stimulates pro-matrix metalloproteinase-2 expression through tumor necrosis factor-alpha in human dermal fibroblasts.
Neoplasms
Prostate carcinoma and green tea: PSA-triggered basement membrane degradation and MMP-2 activation are inhibited by (-)epigallocatechin-3-gallate.
Neoplasms
Protease-Activable Cell-Penetrating Peptide-Protoporphyrin Conjugate for Targeted Photodynamic Therapy in Vivo.
Neoplasms
Proteases and invasion by metastatic tumor-cells - clinical implications for prostate-cancer.
Neoplasms
Protective effect of bicyclol against bile duct ligation-induced hepatic fibrosis in rats.
Neoplasms
Protective effects of fermented rice vinegar sediment (Kurozu moromimatsu) in a diethylnitrosamine-induced hepatocellular carcinoma animal model.
Neoplasms
Protective effects of selective mineralocorticoid receptor antagonist against aortic aneurysm progression in a novel murine model.
Neoplasms
Protein expression of matrix metalloproteinases 2 and 9 and tissue inhibitors of metalloproteinase 1 and 2 in papillary thyroid carcinomas.
Neoplasms
Protein Expression of MMP-2 and MT1-MMP in Actinic Keratosis, Squamous Cell Carcinoma of the Skin, and Basal Cell Carcinoma.
Neoplasms
Protein inhibitor of activated STAT-1 is downregulated in gastric cancer tissue and involved in cell metastasis.
Neoplasms
Protein kinase D1 inhibits cell proliferation through matrix metalloproteinase-2 and matrix metalloproteinase-9 secretion in prostate cancer.
Neoplasms
Protein-bound polysaccharide PSK inhibits tumor invasiveness by down-regulation of TGF-beta1 and MMPs.
Neoplasms
Proteolysis-Responsive Rolling Circle Transcription Assay Enabling Femtomolar Sensitivity Detection of a Target Protease Biomarker.
Neoplasms
Proteolytic activity of human lymphoid tumor cells. Correlation with tumor progression.
Neoplasms
Proteolytic enzymes in tumor metastasis. II. Collagenase type IV activity in subcellular fractions of cloned tumor cell populations.
Neoplasms
Proteolytic imbalance is reversed after therapeutic surgery in breast cancer patients.
Neoplasms
Proteome profiling of U2OS cell line in response to a prenylphenol antibiotic isolated from a phytopathogenic fungus.
Neoplasms
Protocatechuic acid inhibits cancer cell metastasis involving the down-regulation of Ras/Akt/NF-?B pathway and MMP-2 production by targeting RhoB activation.
Neoplasms
PSY-1, a Taxus chinensis var. mairei extract, inhibits cancer cell metastasis by interfering with MMPs.
Neoplasms
Psychological Stress Up-Regulates CD147 Expression Through Beta-Arrestin1/ERK to Promote Proliferation and Invasiveness of Glioma Cells.
Neoplasms
Pterostilbene Inhibits Adipocyte Conditioned-Medium-Induced Colorectal Cancer Cell Migration through Targeting FABP5-Related Signaling Pathway.
Neoplasms
Pulsed Electromagnetic Field Modulates Tendon Cells Response in IL-1?-Conditioned Environment.
Neoplasms
Purification and characterization of catalytic domains of gelatinase A with or without fibronectin insert for high-throughput inhibitor screening.
Neoplasms
Purification of a gelatin-degrading type IV collagenase secreted by ras oncogene-transformed fibroblasts.
Neoplasms
Pyridine-Containing Macrocycles Display MMP-2/9 Inhibitory Activity and Distinct Effects on Migration and Invasion of 2D and 3D Breast Cancer Models.
Neoplasms
QSAR modelling on a series of arylsulfonamide-based hydroxamates as potent MMP-2 inhibitors.
Neoplasms
Quantification of fibronectin as a method to assess ex vivo extracellular matrix remodeling.
Neoplasms
Quantification of matrix metalloproteinase activity in plasma of patients enrolled in a BAY 12-9566 phase I study.
Neoplasms
Quantitative analysis of matrix metalloproteinase-2 mRNA expression in central and peripheral regions of gliomas.
Neoplasms
Quantitative analysis of melanocytic tissue array reveals inverse correlation between activator protein-2alpha and protease-activated receptor-1 expression during melanoma progression.
Neoplasms
Quantitative cell dispersion analysis: new test to measure tumor cell aggressiveness.
Neoplasms
Quantitative detection of TIMP-3 promoter hypermethylation and its prognostic significance in esophageal squamous cell carcinoma.
Neoplasms
Quantitative estimation of matrix metalloproteinases 2 and 7 (MMP-2, MMP-7) and tissue inhibitors of matrix metalloproteinases 1 and 2 (TIMP-1, TIMP-2) in colorectal carcinoma tissue samples.
Neoplasms
Quantitative proteomics suggest a potential link between early embryonic death and trisomy 16.
Neoplasms
Quantum dots based molecular beacons for in vitro and in vivo detection of MMP-2 on tumor.
Neoplasms
Quercetin Suppresses the Migration and Invasion in Human Colon Cancer Caco-2 Cells Through Regulating Toll-like Receptor 4/Nuclear Factor-kappa B Pathway.
Neoplasms
Quiescin sulfhydryl oxidase 1 promotes invasion of pancreatic tumor cells mediated by matrix metalloproteinases.
Neoplasms
Rac1 mediates type I collagen-dependent MMP-2 activation. role in cell invasion across collagen barrier.
Neoplasms
Radiation enhances long-term metastasis potential of residual hepatocellular carcinoma in nude mice through TMPRSS4-induced epithelial-mesenchymal transition.
Neoplasms
Radiation-enhancement of MDA-MB-231 breast cancer cell invasion prevented by a cyclooxygenase-2 inhibitor.
Neoplasms
Radiation-induced lipoprotein-associated phospholipase A2 increases lysophosphatidylcholine and induces endothelial cell damage.
Neoplasms
Radionuclide imaging of tumor xenografts in mice using a gelatinase-targeting peptide.
Neoplasms
Raf activation by Ras and promotion of cellular metastasis require phosphorylation of prohibitin in the raft domain of the plasma membrane.
Neoplasms
Raf kinase inhibitor protein suppresses nuclear factor-?B-dependent cancer cell invasion through negative regulation of matrix metalloproteinase expression.
Neoplasms
Rapid activation of matrix metalloproteinase-2 by glioma cells occurs through a posttranslational MT1-MMP-dependent mechanism.
Neoplasms
Rapid and highly efficient capture and release of cancer cells using polymeric microfibers immobilized with enzyme-cleavable peptides.
Neoplasms
Rapid release of matrix metalloproteinase (MMP)-2 by thrombin in the rat aorta: modulation by protein tyrosine kinase/phosphatase.
Neoplasms
Rapid trafficking of membrane type 1-matrix metalloproteinase to the cell surface regulates progelatinase a activation.
Neoplasms
Ras pathway is required for the activation of MMP-2 secretion and for the invasion of src-transformed 3Y1.
Neoplasms
Ras-related protein Rap2c promotes the migration and invasion of human osteosarcoma cells.
Neoplasms
Ratiometric Imaging of MMP-2 Activity Facilitates Tumor Detection Using Activatable Near-Infrared Fluorescent Semiconducting Polymer Nanoparticles.
Neoplasms
Realgar Nanoparticles Inhibit Migration, Invasion and Metastasis in a Mouse Model of Breast Cancer by Suppressing Matrix Metalloproteinases and Angiogenesis.
Neoplasms
Recent advances in the regulation of matrix metalloproteinase 2 activation: from basic research to clinical implication (Review).
Neoplasms
Recent opportunities in matrix metalloproteinase inhibitor drug design for cancer.
Neoplasms
RECK-mediated suppression of tumor cell invasion is regulated by glycosylation in human tumor cell lines.
Neoplasms
Recombinant CBD-HepII polypeptide of fibronectin inhibits alphavbeta3 signaling and hematogenous metastasis of tumor.
Neoplasms
Recombinant expression and downstream processing of the disulfide-rich tumor-targeting peptide chlorotoxin.
Neoplasms
Recombinant human prothrombin kringle-2 inhibits B16F10 melanoma metastasis through inhibition of neovascularization and reduction of matrix metalloproteinase expression.
Neoplasms
Recombinant viral protein promotes apoptosis and suppresses invasion of ovarian adenocarcinoma cells by targeting ?5?1 integrin to downregulate Akt and MMP-2.
Neoplasms
Red ginseng extract reduced metastasis of colon cancer cells in vitro and in vivo.
Neoplasms
Redox- and MMP-2-sensitive drug delivery nanoparticles based on gelatin and albumin for tumor targeted delivery of paclitaxel.
Neoplasms
Reduction of alachlor-induced olfactory mucosal neoplasms by the matrix metalloproteinase inhibitor Ro 28-2653.
Neoplasms
Reduction of in vivo tumor growth by MMI-166, a selective matrix metalloproteinase inhibitor, through inhibition of tumor angiogenesis in squamous cell carcinoma cell lines of head and neck.
Neoplasms
Regulation of 92-kD gelatinase release in HL-60 leukemia cells: tumor necrosis factor-alpha as an autocrine stimulus for basal- and phorbol ester-induced secretion.
Neoplasms
Regulation of angiogenesis and invasion by human Pituitary tumor transforming gene (PTTG) through increased expression and secretion of matrix metalloproteinase-2 (MMP-2).
Neoplasms
Regulation of gelatinase production and invasiveness by organ-specific fibroblasts in high- and low-metastatic clones from murine RCT sarcoma.
Neoplasms
Regulation of gelatinases expression by cytokines, endotoxin, and pharmacological agents in the human osteoarthritic knee.
Neoplasms
Regulation of gelatinases in human airway smooth muscle cells: mechanism of progelatinase A activation.
Neoplasms
Regulation of kinesin expression and type IV collagenase secretion in invasive human prostate PC-3 tumor sublines.
Neoplasms
Regulation of matrix metalloproteinase expressions in astrocytes, microglia and neurons.
Neoplasms
Regulation of matrix metalloproteinase-9 gene expression and cell migration by NF-kappaB in response to CpG-oligodeoxynucleotides in RAW 264.7 cells.
Neoplasms
Regulation of matrix metalloproteinases - their role in tumor invasion and metastasis.
Neoplasms
Regulation of MMP-1 and MMP-2 production through CD147/extracellular matrix metalloproteinase inducer interactions.
Neoplasms
Regulation of MMP-9 (92 kDa type IV collagenase/gelatinase B) expression in stromal cells of human giant cell tumor of bone.
Neoplasms
Regulation of MT1-MMP and MMP-2 by the serpin PEDF: a promising new target for metastatic cancer.
Neoplasms
Regulation of the Mr 72,000 type IV collagenase by the type I insulin-like growth factor receptor.
Neoplasms
Relation of enhanced secretion of active matrix metalloproteinases with tumor spread in human hepatocellular carcinoma.
Neoplasms
Relationship between expression of matrix metalloproteinase-2 and matrix metalloproteinase-9 and invasion ability of cervical cancer cells.
Neoplasms
Relationship between matrix metalloproteinase-2 mRNA expression and clinicopathological and urokinase-type plasminogen activator system parameters and prognosis in human gastric cancer.
Neoplasms
Relationship between metalloprotease expression in tumour and stromal cells and aggressive behaviour in prostate carcinoma: Simultaneous high-throughput study of multiple metalloproteases and their inhibitors using tissue array analysis of radical prostatectomy samples.
Neoplasms
Relationship between protein expression of VEGF-C, MMP-2 and lymph node metastasis in papillary thyroid cancer.
Neoplasms
Relationship between the expression of VEGF signal components and matrix metalloproteinases in ovarian tumors.
Neoplasms
Relationships Between Immunophenotype, Ki-67 Index, Microvascular Density, Ep-CAM/P-cadherin, and MMP-2 Expression in Early-stage Invasive Ductal Breast Cancer.
Neoplasms
Relationships between the level of matrix metalloproteinase-2 and tumor size of breast cancer.
Neoplasms
Relative expression of ?-smooth muscle actin and matrix metalloproteinases-2 in ameloblastoma of a black African sub-population.
Neoplasms
Relative expression of E-cadherin and type IV collagenase genes predicts disease outcome in patients with resectable pancreatic carcinoma.
Neoplasms
Relative expression of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in mouse renal cell carcinoma cells regulates their metastatic potential.
Neoplasms
Relative expression of type IV collagenase, E-cadherin, and vascular endothelial growth factor/vascular permeability factor in prostatectomy specimens distinguishes organ-confined from pathologically advanced prostate cancers.
Neoplasms
Release of gelatinase A (matrix metalloproteinase 2) induced by photolysis of caged phosphatidic acid in HT 1080 metastatic fibrosarcoma cells.
Neoplasms
Relevance of biologic markers in colorectal carcinoma: a comparative study of a broad panel.
Neoplasms
Reliability of tumor markers, chemokines, and metastasis-related molecules in serum.
Neoplasms
Remodeling of collagen matrix by human tumor cells requires activation and cell surface association of matrix metalloproteinase-2.
Neoplasms
Reoxygenation using a novel CO2 therapy decreases the metastatic potential of osteosarcoma cells.
Neoplasms
Repression of 92-kDa type IV collagenase expression by MTA1 is mediated through direct interactions with the promoter via a mechanism, which is both dependent on and independent of histone deacetylation.
Neoplasms
Restricted expression of membrane type 1-matrix metalloproteinase by myofibroblasts adjacent to human breast cancer cells.
Neoplasms
Resveratrol Inhibits the Epithelial-Mesenchymal Transition of Pancreatic Cancer Cells Via Suppression of the PI-3K/Akt/NF-?B Pathway.
Neoplasms
Retinoic acid stimulates meningioma cell adhesion to the extracellular matrix and inhibits invasion.
Neoplasms
Retinoic acid synergizes with cyclic AMP to enhance MMP-2 basal promoter activity.
Neoplasms
Retraction: Hyperbaric oxygen activates discoidin domain receptor 2 via tumour necrosis factor-? and the p38 MAPK pathway to increase vascular smooth muscle cell migration through matrix metalloproteinase 2.
Neoplasms
Reverse transcription-polymerase chain reaction phenotyping of metalloproteinases and inhibitors involved in tumor matrix invasion.
Neoplasms
Reversion-inducing-cysteine-rich protein with Kazal motif is involved in intimal hyperplasia in carotid arteries: a new insight in the prevention of restenosis after vascular angioplasty.
Neoplasms
Rho-kinase inhibitor, fasudil, suppresses glioblastoma cell line progression in vitro and in vivo.
Neoplasms
Rock2 promotes the invasion and metastasis of hepatocellular carcinoma by modifying MMP2 ubiquitination and degradation.
Neoplasms
Role of acetylation and extracellular location of heat shock protein 90alpha in tumor cell invasion.
Neoplasms
Role of Daucosterol Linoleate on Breast Cancer: Studies on Apoptosis and Metastasis.
Neoplasms
Role of Endoplasmic Reticulum Stress in Proinflammatory Cytokine-Mediated Inhibition of Trophoblast Invasion in Placenta-Related Complications of Pregnancy.
Neoplasms
Role of GPER on proliferation, migration and invasion in ligand-independent manner in human ovarian cancer cell line SKOV3.
Neoplasms
Role of immunohistochemical overexpression of matrix metalloproteinases MMP-2 and MMP-11 in the prognosis of death by ovarian cancer.
Neoplasms
Role of interleukin 10 and transforming growth factor beta1 in the angiogenesis and metastasis of human prostate primary tumor lines from orthotopic implants in severe combined immunodeficiency mice.
Neoplasms
Role of L1 cell adhesion molecule (L1CAM) in the metastatic cascade: promotion of dissemination, colonization, and metastatic growth.
Neoplasms
Role of matrix metalloproteinase-2 in ethanol-induced invasion by breast cancer cells.
Neoplasms
Role of matrix metalloproteinase-9 in the basement membrane destruction of superficial urothelial carcinomas.
Neoplasms
Role of matrix metalloproteinases 2 and 9 in determination of invasive potential of pancreatic tumors.
Neoplasms
Role of MCP-1 on inflammatory processes and metabolic dysfunction following high-fat feedings in the FVB/N strain.
Neoplasms
Role of membrane type 1-matrix metalloproteinase and gelatinase A in head and neck squamous cell carcinoma invasion in vitro.
Neoplasms
Role of MMP-2 in the regulation of IL-6/Stat3 survival signaling via interaction with ?5?1 integrin in glioma.
Neoplasms
Role of MMP-9 and its tissue inhibitor TIMP-1 in human osteosarcoma: findings in 42 patients followed for 1-16 years.
Neoplasms
Role of N-acetylcysteine and GSH redox system on total and active MMP-2 in intestinal myofibroblasts of Crohn's disease patients.
Neoplasms
Role of phospholipase D in laminin-induced production of gelatinase A (MMP-2) in metastatic cells.
Neoplasms
Role of reactive oxygen species (ROS), metalloproteinase-2 (MMP-2) and interleukin-6 (IL-6) in direct interactions between tumour cell spheroids and endothelial cell monolayer.
Neoplasms
Role of serum matrix metalloproteinase-2 and -9 to predict breast cancer progression.
Neoplasms
Role of siRNA silencing of MMP-2 gene on invasion and growth of laryngeal squamous cell carcinoma.
Neoplasms
Role of the matrix metalloproteinase and tissue inhibitors of metalloproteinase families in noninvasive and invasive tumors transplanted in mice with severe combined immunodeficiency.
Neoplasms
Role of tissue inhibitor of metalloproteinases-2 (TIMP-2) in regulation of pro-gelatinase A activation catalyzed by membrane-type matrix metalloproteinase-1 (MT1-MMP) in human cancer cells.
Neoplasms
Role of tumor necrosis factor-alpha in the premature rupture of membranes and preterm labor pathways.
Neoplasms
Role of tumor-derived granulocyte-macrophage colony-stimulating factor in mice bearing a highly invasive and metastatic mammary carcinoma.
Neoplasms
Roles of membrane type 1 matrix metalloproteinase and tissue inhibitor of metalloproteinases 2 in invasion and dissemination of human malignant glioma.
Neoplasms
Roles of microsomal prostaglandin E synthase-1 in lung metastasis formation in prostate cancer RM9 cells.
Neoplasms
ROR2 promotes the epithelial-mesenchymal transition by regulating MAPK/p38 signaling pathway in breast cancer.
Neoplasms
Russian study of morphological prognostic factors characterization in BRAF-mutant cutaneous melanoma.
Neoplasms
S-adenosylmethionine, a methyl donor, up regulates tissue inhibitor of metalloproteinase-2 in colorectal cancer.
Neoplasms
S-Nitrosocaptopril prevents cancer metastasis in vivo by creating the hostile bloodstream microenvironment against circulating tumor cells.
Neoplasms
S100A4 antisense oligodeoxynucleotide suppresses invasive potential of neuroblastoma cells.
Neoplasms
S100A4 regulates membrane induced activation of matrix metalloproteinase-2 in osteosarcoma cells.
Neoplasms
S100A8/A9 regulates MMP-2 expression and invasion and migration by carcinoma cells.
Neoplasms
Salvianolic acid A suppresses MMP-2 expression and restrains cancer cell invasion through ERK signaling in human nasopharyngeal carcinoma.
Neoplasms
Salvianolic acid B from Salvia miltiorrhiza inhibits tumor necrosis factor-alpha (TNF-alpha)-induced MMP-2 upregulation in human aortic smooth muscle cells via suppression of NAD(P)H oxidase-derived reactive oxygen species.
Neoplasms
Salvianolic acid B protects from pulmonary microcirculation disturbance induced by lipopolysaccharide in rat.
Neoplasms
Saponins derived from the roots of Platycodon grandiflorum inhibit HT-1080 cell invasion and MMPs activities: regulation of NF-kappaB activation via ROS signal pathway.
Neoplasms
SB203580, a p38 mitogen-activated protein kinase inhibitor, suppresses the development of endometriosis by down-regulating proinflammatory cytokines and proteolytic factors in a mouse model.
Neoplasms
Screening of the residual normal ovarian tissue adjacent to orthotopic epithelial ovarian carcinomas in nude mice.
Neoplasms
SCUBE3 is an endogenous TGF-? receptor ligand and regulates the epithelial-mesenchymal transition in lung cancer.
Neoplasms
Secretion and Expression of Matrix Metalloproteinase-2 and 9 from Bone Marrow Mononuclear Cells in Myelodysplastic Syndrome and Acute Myeloid Leukemia.
Neoplasms
Secretion of extracellular hsp90alpha via exosomes increases cancer cell motility: a role for plasminogen activation.
Neoplasms
Secretion of type IV collagenolytic protease and metastatic phenotype: induction by transfection with c-Ha-ras but not c-Ha-ras plus Ad2-E1a.
Neoplasms
Selected Matrix Metalloproteinases (MMP-2, MMP-7) and Their Inhibitor (TIMP-2) in Adult and Pediatric Cancer.
Neoplasms
Selection of a histidine-containing inhibitor of gelatinases through deconvolution of combinatorial tetrapeptide libraries.
Neoplasms
Selection of peptide inhibitor to matrix metalloproteinase-2 using phage display and its effects on pancreatic cancer cell lines PANC-1 and CFPAC-1.
Neoplasms
Selection of potential markers for epithelial ovarian cancer with gene expression arrays and recursive descent partition analysis.
Neoplasms
Selective gelatinase inhibitor peptide is effective in targeting tongue carcinoma cell tumors in vivo.
Neoplasms
Selective gene transfer to endometrial cancer cells by a polymer against matrix metalloproteinase 2 (MMP-2).
Neoplasms
Selective inhibition of matrix metalloproteinase-2 in the multiple myeloma-bone microenvironment.
Neoplasms
Selective photodynamic effects on cervical cancer cells provided by P123 Pluronic®-based nanoparticles modulating hypericin delivery.
Neoplasms
Self-assembled nanomedicine combining a berberine derivative and doxorubicin for enhanced antitumor and antimetastatic efficacy via mitochondrial pathways.
Neoplasms
SEMA4D Knockdown Attenuates ?-Catenin-Dependent Tumor Progression in Colorectal Cancer.
Neoplasms
Semi-quantitative expression of tissue inhibitor of matrix metalloproteinase-2 in cancer of uterine cervix.
Neoplasms
Senescent fibroblasts enhance early skin carcinogenic events via a paracrine MMP-PAR-1 axis.
Neoplasms
Sensitive surface enhanced Raman scattering multiplexed detection of matrix metalloproteinase 2 and 7 cancer markers.
Neoplasms
Seprase, a membrane-type serine protease, has different expression patterns in intestinal- and diffuse-type gastric cancer.
Neoplasms
Sequential activation and production of matrix metalloproteinase-2 during breast cancer progression.
Neoplasms
Sequentially Responsive Therapeutic Peptide Assembling Nanoparticles for Dual-Targeted Cancer Immunotherapy.
Neoplasms
Serous and mucinous ovarian tumors express different profiles of MMP-2, -7, -9, MT1-MMP, and TIMP-1 and -2.
Neoplasms
Serum and plasma M(r) 92,000 progelatinase levels correlate with spontaneous metastasis of rat 13762NF mammary adenocarcinoma.
Neoplasms
Serum levels and tissue expression of matrix metalloproteinase 2 (MMP-2) and tissue inhibitor of metalloproteinases 2 (TIMP-2) in colorectal cancer patients.
Neoplasms
Serum levels of matrix metalloproteinase-2 and -9 and conventional tumor markers (CEA and CA 19-9) in patients with colorectal and gastric cancers.
Neoplasms
Serum levels of matrix metalloproteinase-9 predict lymph node metastasis in breast cancer patients.
Neoplasms
Serum levels of matrix metalloproteinases MMP-2 and MMP-9 and their tissue natural inhibitors in breast tumors.
Neoplasms
Serum markers of matrix turnover as predictors for the evolution of colorectal cancer metastasis under chemotherapy.
Neoplasms
Serum matrix metalloproteinase 2 and tissue inhibitor of matrix metalloproteinases 2 in esophageal cancer patients.
Neoplasms
Serum metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in lung carcinoma patients.
Neoplasms
Sesquiterpene lactone Zaluzanin D alters MMP-9 promoter methylation in differentiated THP-1 monocytic cells and down regulates inflammatory cytokines IL-1? and TNF-?.
Neoplasms
SETD3 acts as a prognostic marker in breast cancer patients and modulates the viability and invasion of breast cancer cells.
Neoplasms
Severity of Plasma Leakage Is Associated With High Levels of Interferon ?-Inducible Protein 10, Hepatocyte Growth Factor, Matrix Metalloproteinase 2 (MMP-2), and MMP-9 During Dengue Virus Infection.
Neoplasms
Sevoflurane and thiopental preconditioning attenuates the migration and activity of MMP-2 in U87MG glioma cells.
Neoplasms
Sheddable Prodrug Vesicles Combating Adaptive Immune Resistance for Improved Photodynamic Immunotherapy of Cancer.
Neoplasms
Shenkang VII Recipe Attenuates Unilateral Ureteral Obstruction-induced Renal Fibrosis via TGF-?/Smad, NF-?B and SHH Signaling Pathway.
Neoplasms
Short hairpin RNA targeting autotaxin reduces human gastric carcinoma AGS cell proliferative, migratory and invasive capabilities in vitro and causes tumor regression in vivo.
Neoplasms
Short interfering RNA directed against Slug blocks tumor growth, metastasis formation, and vascular leakage in bladder cancer.
Neoplasms
ShRNA knock-down of CXCR7 inhibits tumour invasion and metastasis in hepatocellular carcinoma after transcatheter arterial chemoembolization.
Neoplasms
ShRNA-mediated matrix metalloproteinase-2 gene silencing protects normal cells and sensitizes cancer cells against ionizing-radiation induced damage.
Neoplasms
Significance of lymphatic invasion and cancer invasion-related proteins on lymph node metastasis in gastric cancer.
Neoplasms
Significance of matrix metalloproteinases and tissue inhibitors of metalloproteinase expression in the recurrence of superficial transitional cell carcinoma of the bladder.
Neoplasms
Significance of MMP-2 expression in prostate cancer: an immunohistochemical study.
Neoplasms
Significant Relation of Tissue Inhibitor of Matrix Metalloproteinase-2 and its Combination With Matrix Metalloproteinase-2 to Survival of Patients With Cancer of Uterine Cervix.
Neoplasms
Silence of Stomatin-Like Protein 2 Represses Migration and Invasion Ability of Human Liver Cancer Cells via Inhibiting the Nuclear Factor Kappa B (NF-?B) Pathway.
Neoplasms
Silencing cAMP-response element-binding protein (CREB) identifies CYR61 as a tumor suppressor gene in melanoma.
Neoplasms
Silencing KRAS Overexpression in Cadmium-Transformed Prostate Epithelial Cells Mitigates Malignant Phenotype.
Neoplasms
Silencing of calpain expression reduces the metastatic potential of human osteosarcoma cells.
Neoplasms
Silencing of HMGA2 suppresses cellular proliferation, migration, invasion, and epithelial-mesenchymal transition in bladder cancer.
Neoplasms
Silencing of LINC00461 enhances radiosensitivity of lung adenocarcinoma cells by down-regulating HOXA10 via microRNA-195.
Neoplasms
Silencing of the Long Non-Coding RNA TTN-AS1 Attenuates the Malignant Progression of Osteosarcoma Cells by Regulating the miR-16-1-3p/TFAP4 Axis.
Neoplasms
Silibinin inhibits cell invasion through inactivation of both PI3K-Akt and MAPK signaling pathways.
Neoplasms
Silibinin inhibits invasion of oral cancer cells by suppressing the MAPK pathway.
Neoplasms
Silibinin inhibits the invasion of human lung cancer cells via decreased productions of urokinase-plasminogen activator and matrix metalloproteinase-2.
Neoplasms
Silymarin-loaded Eudragit(®) RS100 nanoparticles improved the ability of silymarin to resolve hepatic fibrosis in bile duct ligated rats.
Neoplasms
Similarities of in situ mRNA expression between gelatinase A (MMP-2) and type I procollagen in human gastrointestinal carcinoma: comparison with granulation tissue reaction.
Neoplasms
Simultaneous presence of unsaturation and long alkyl chain at P'1 of Ilomastat confers selectivity for gelatinase A (MMP-2) over gelatinase B (MMP-9) inhibition as shown by molecular modelling studies.
Neoplasms
Simvastatin Suppresses Human Breast Cancer Cell Invasion by Decreasing the Expression of Pituitary Tumor-Transforming Gene 1.
Neoplasms
Sine oculis homeobox homolog 1 promotes ?5?1-mediated invasive migration and metastasis of cervical cancer cells.
Neoplasms
Single-nucleotide polymorphisms and haplotypes of membrane type 1-matrix metalloproteinase in susceptibility and clinical significance of squamous cell neoplasia of uterine cervix in taiwan women.
Neoplasms
SIRT1 enhances matrix metalloproteinase-2 expression and tumor cell invasion in prostate cancer cells.
Neoplasms
SKI-606 (Bosutinib) Blocks Prostate Cancer Invasion, Growth, and Metastasis In vitro and In vivo through Regulation of Genes Involved in Cancer Growth and Skeletal Metastasis.
Neoplasms
Skin property can predict the development of skin tears among elderly patients: a prospective cohort study.
Neoplasms
Small GTP-binding protein, Rho, both increased and decreased cellular motility, activation of matrix metalloproteinase 2 and invasion of human osteosarcoma cells.
Neoplasms
Small integrin binding ligand N-linked glycoprotein gene family expression in different cancers.
Neoplasms
Smart Nanodrug with Nuclear Localization Sequences in the Presence of MMP-2 To Overcome Biobarriers and Drug Resistance.
Neoplasms
SNS-032 prevents hypoxia-mediated glioblastoma cell invasion by inhibiting hypoxia inducible factor-1alpha expression.
Neoplasms
Social defeat stress promotes tumor growth and angiogenesis by upregulating vascular endothelial growth factor/extracellular signal-regulated kinase/matrix metalloproteinase signaling in a mouse model of lung carcinoma.
Neoplasms
Sodium caffeate induces endothelial cell apoptosis and inhibits VEGF expression in cancer cells.
Neoplasms
Sodium Intake Is associated With Endothelial Damage Biomarkers and Metabolic Dysregulation.
Neoplasms
Solanine induces mitochondria-mediated apoptosis in human pancreatic cancer cells.
Neoplasms
Soluble E-cadherin: a critical oncogene modulating receptor tyrosine kinases, MAPK and PI3K/Akt/mTOR signaling.
Neoplasms
Soluble form of ephrinB2 inhibits xenograft growth of squamous cell carcinoma of the head and neck.
Neoplasms
Soluble IL-6R alpha upregulated IL-6, MMP-1 and MMP-2 secretion in bone marrow stromal cells.
Neoplasms
Solution structure and backbone dynamics of the catalytic domain of matrix metalloproteinase-2 complexed with a hydroxamic acid inhibitor.
Neoplasms
Sorafenib suppresses the epithelial-mesenchymal transition of hepatocellular carcinoma cells after insufficient radiofrequency ablation.
Neoplasms
Soybean saponin inhibits tumor cell metastasis by modulating expressions of MMP-2, MMP-9 and TIMP- 2.
Neoplasms
SPARC is associated with gastric cancer progression and poor survival of patients.
Neoplasms
SPARC/osteonectin induces matrix metalloproteinase 2 activation in human breast cancer cell lines.
Neoplasms
SPARCL1 is a novel predictor of tumor recurrence and survival in hilar cholangiocarcinoma.
Neoplasms
Spatial controlled multistage nanocarriers through hybridization of dendrimers and gelatin nanoparticles for deep penetration and therapy into tumor tissue.
Neoplasms
Spatiotemporal expression profile of proteases and immunological, angiogenic, hormonal and apoptotic mediators in rat placenta before and during intrauterine trophoblast migration.
Neoplasms
Specific interaction between chitosan and matrix metalloprotease 2 decreases the invasive activity of human melanoma cells.
Neoplasms
Specific matrix metalloproteinase profiles in the cerebrospinal fluid correlated with the presence of malignant astrocytomas, brain metastases, and carcinomatous meningitis.
Neoplasms
Spectrum of matrix metalloproteinase expression in primary and metastatic colon cancer: relationship to the tissue inhibitors of metalloproteinases and membrane type-1-matrix metalloproteinase.
Neoplasms
Spironolactone prevents alterations associated with cardiac hypertrophy produced by isoproterenol in rats: involvement of SGK-1.
Neoplasms
Spreds, inhibitors of the Ras/ERK signal transduction, are dysregulated in human hepatocellular carcinoma and linked to the malignant phenotype of tumors.
Neoplasms
Squamous cell carcinoma growth in mice and in culture is regulated by c-Jun and its control of matrix metalloproteinase-2 and -9 expression.
Neoplasms
Src kinase regulates metalloproteinase-9 secretion induced by type IV collagen in MCF-7 human breast cancer cells.
Neoplasms
Standardized Salvia miltiorrhiza extract suppresses hepatic stellate cell activation and attenuates steatohepatitis induced by a methionine-choline deficient diet in mice.
Neoplasms
Stat3 activation regulates the expression of matrix metalloproteinase-2 and tumor invasion and metastasis.
Neoplasms
Stat3 Is Involved in Angiotensin II-Induced Expression of MMP2 in Gastric Cancer Cells.
Neoplasms
Stimulation of matrix metalloproteinase-9 expression in human fibrosarcoma cells by synthetic matrix metalloproteinase inhibitors.
Neoplasms
Stimulation of the 92-kD type IV collagenase promoter and enzyme expression in human melanoma cells.
Neoplasms
Stimulation of type IV collagenase expression by linoleic acid in a metastatic human breast cancer cell line.
Neoplasms
Stoichiometric expression of MMP-2/TIMP-2 in benign and malignant tumours of the salivary gland.
Neoplasms
Stomach Cancer: Interconnection between the Redox State, Activity of MMP-2, MMP-9 and Stage of Tumor Growth.
Neoplasms
Stroma-derived matrix metalloproteinase (MMP)-2 promotes membrane type 1-MMP-dependent tumor growth in mice.
Neoplasms
Stromal cells as the major source for matrix metalloproteinase-2 in cutaneous melanoma.
Neoplasms
Stromal cells play a role in cervical cancer progression mediated by MMP-2 protein.
Neoplasms
Stromal expression of 72 kda type IV collagenase (MMP-2) and TIMP-2 mRNAs in colorectal neoplasia.
Neoplasms
Stromal expression of fibroblast activation protein/seprase, a cell membrane serine proteinase and gelatinase, is associated with longer survival in patients with invasive ductal carcinoma of breast.
Neoplasms
Stromal expression of matrix metalloproteinase 2 in cancer-associated fibroblasts is strongly related to human epidermal growth factor receptor 2 status in invasive breast carcinoma.
Neoplasms
Stromal fibroblasts adjacent to invasive thyroid tumors: expression of gelatinase A but not stromelysin 3 mRNA.
Neoplasms
Stromal matrix metalloproteinase-9 regulates the vascular architecture in neuroblastoma by promoting pericyte recruitment.
Neoplasms
Stromal-epithelial interaction in type IV collagenase expression and activation: The role in cancer metastasis.
Neoplasms
Stromelysin-3 mRNA expression and malignancy: comparison with clinicopathological features and type IV collagenase mRNA expression in breast tumors.
Neoplasms
Strong significant correlation between MMP-9 and systemic symptoms in patients with localized renal cell carcinoma.
Neoplasms
Structural characterization of the mesangial cell type IV collagenase and enhanced expression in a model of immune complex-mediated glomerulonephritis.
Neoplasms
Studies on the expression of alpha(v)beta3 integrin receptors in non-malignant and malignant human cervical tumor tissues.
Neoplasms
Study on antitumor activities of the chrysin-chromene-spirooxindole on Lewis lung carcinoma C57BL/6 mice in vivo.
Neoplasms
Study on Medication Rules of Traditional Chinese Medicine against Antineoplastic Drug-Induced Cardiotoxicity Based on Network Pharmacology and Data Mining.
Neoplasms
Study on the expression of p53 and MMP-2 in patients with lung cancer after interventional therapy.
Neoplasms
Subcurative radiation significantly increases proliferation, invasion, and migration of primary GBM in vivo.
Neoplasms
Suberoylanilide hydroxamic acid (Zolinza/vorinostat) sensitizes TRAIL-resistant breast cancer cells orthotopically implanted in BALB/c nude mice.
Neoplasms
Sublethal dose of irradiation enhances invasion of malignant glioma cells through p53-MMP 2 pathway in U87MG mouse brain tumor model.
Neoplasms
Sublethal irradiation promotes migration and invasiveness of glioma cells: implications for radiotherapy of human glioblastoma.
Neoplasms
Substrate-zymography: a still worthwhile method for gelatinases analysis in biological samples.
Neoplasms
Sulphonamide 1,4-dithia-7-azaspiro[4,4]nonane derivatives as gelatinase A inhibitors.
Neoplasms
Superoxide- and NO-dependent mechanisms of antitumor and antimetastatic effect of L-arginine hydrochloride and coenzyme Q10.
Neoplasms
Suppression of carbonyl reductase expression enhances malignant behaviour in uterine cervical squamous cell carcinoma: Carbonyl reductase predicts prognosis and lymph node metastasis.
Neoplasms
Suppression of hepatocarcinoma model in vitro and in vivo by ECRG2 delivery using adenoviral vector.
Neoplasms
Suppression of matrix metalloproteinase-2 gene expression and invasion in human glioma cells by MMAC/PTEN.
Neoplasms
Suppression of matrix metalloproteinase-2 via RNA interference inhibits pancreatic carcinoma cell invasiveness and adhesion.
Neoplasms
Suppression of membrane-type 1 matrix metalloproteinase (MMP)-mediated MMP-2 activation and tumor invasion by testican 3 and its splicing variant gene product, N-Tes.
Neoplasms
Suppression of MMP-2 attenuates TNF-? induced NF-?B activation and leads to JNK mediated cell death in glioma.
Neoplasms
Suppression of phospho-p85?-GTP-Rac1 lipid raft interaction by bichalcone analog attenuates cancer cell invasion.
Neoplasms
Suppression of tumor cell invasiveness and in vivo tumor growth by microRNA-874 in non-small cell lung cancer.
Neoplasms
Suppression of tumor cell invasiveness by hydrolyzable tannins (plant polyphenols) via the inhibition of matrix metalloproteinase-2/-9 activity.
Neoplasms
Suppressive Effects of Plumbagin on Invasion and Migration of Breast Cancer Cells via the Inhibition of STAT3 Signaling and Down-regulation of Inflammatory Cytokine Expressions.
Neoplasms
Supramolecular Aggregation-Induced Emission Nanodots with Programmed Tumor Microenvironment Responsiveness for Image-Guided Orthotopic Pancreatic Cancer Therapy.
Neoplasms
Surfactin from Bacillus subtilis attenuates ambient air particulate matter-promoted human oral cancer cells metastatic potential.
Neoplasms
Survey of risk factors contributed to lymphatic metastasis in patients with oral tongue cancer by immunohistochemistry.
Neoplasms
SV40 T/t-common polypeptide inhibits angiogenesis and growth of HER2-overexpressing human ovarian cancer.
Neoplasms
Synergistic and protective effect of atorvastatin and amygdalin against histopathological and biochemical alterations in Sprague-Dawley rats with experimental endometriosis.
Neoplasms
Synergistic anticancer effects of timosaponin AIII and ginsenosides in MG63 human osteosarcoma cells.
Neoplasms
Synergistic effects of Endostar combined with ?-elemene on malignant ascites in a mouse model.
Neoplasms
Synergistic efficacy of Cullin1 and MMP-2 expressions in diagnosis and prognosis of colorectal cancer.
Neoplasms
Synergistic induction of cancer cell migration regulated by G?? and phosphatidylinositol 3-kinase.
Neoplasms
Synergistic Inhibitory Effect of Traditional Chinese Medicine Astragaloside IV and Curcumin on Tumor Growth and Angiogenesis in an Orthotopic Nude-Mouse Model of Human Hepatocellular Carcinoma.
Neoplasms
Synthesis and degradation of basement membranes in benign and malignant salivary gland tumours. A study by in situ hybridization.
Neoplasms
Synthesis and Evaluation of a Novel Hydroxamate Based Fluorescent Photoprobe for Imaging of Matrix Metalloproteinases.
Neoplasms
Synthesis and preliminary evaluation in tumor bearing mice of new (18)f-labeled arylsulfone matrix metalloproteinase inhibitors as tracers for positron emission tomography.
Neoplasms
Synthesis of a beta-tetrapeptide analog as a mother compound for the development of matrix metalloproteinase-2-imaging agents.
Neoplasms
Synthesis, anticancer activity, structure-activity relationship and binding mode of interaction studies of substituted pentanoic acids.
Neoplasms
Synthesis, Biological Evaluation, and Docking of Dihydropyrazole Sulfonamide Containing 2-hydroxyphenyl Moiety: A Series of Novel MMP-2 Inhibitors.
Neoplasms
Synthesis, Kinetic Characterization and Metabolism of Diastereomeric 2-(1-(4-Phenoxyphenylsulfonyl)ethyl)thiiranes as Potent Gelatinase and MT1-MMP Inhibitors.
Neoplasms
Synthesis, structure and characterization of novel Cd(II) and Zn(II) complexes with the condensation product of 2-formylpyridine and selenosemicarbazide Antiproliferative activity of the synthesized complexes and related selenosemicarbazone complexes.
Neoplasms
Synthesized tetrahydroisoquinoline alkaloid exerts anticancer effects at least in part by suppressing NF??B?regulated proteins in A549 human lung cancer cells.
Neoplasms
Synthetic emmprin peptides inhibit tumor cell-fibroblast interaction-stimulated upregulation of MMP-2 and tumor cell invasion.
Neoplasms
Systemic and alveolar inflammatory response in the dependent and nondependent lung in patients undergoing lung resection surgery: A prospective observational study.
Neoplasms
Systemic delivery of protein nanocages bearing CTT peptides for enhanced imaging of MMP-2 expression in metastatic tumor models.
Neoplasms
Systemic hypoxia potentiates anti-tumor effects of metformin in hepatocellular carcinoma in mice.
Neoplasms
Systemic Th17-like cytokine pattern in gangrenous appendicitis but not in phlegmonous appendicitis.
Neoplasms
SZ-117, a monoclonal antibody against matrix metalloproteinase-2 inhibits tumor cell-mediated angiogenesis.
Neoplasms
Tacorin, an extract from Ananas comosus stem, stimulates wound healing by modulating the expression of tumor necrosis factor ?, transforming growth factor ? and matrix metalloproteinase 2.
Neoplasms
Target-selective activation of a TNF prodrug by urokinase-type plasminogen activator (uPA) mediated proteolytic processing at the cell surface.
Neoplasms
Targeted Delivery of Secretory Promelittin via Novel Poly(lactone-co-?-amino ester) Nanoparticles for Treatment of Breast Cancer Brain Metastases.
Neoplasms
Targeted MMP-2 responsive chimeric polymersomes for therapy against colorectal cancer.
Neoplasms
Targeted therapy against VEGFR and EGFR with ZD6474 enhances the therapeutic efficacy of irradiation in an orthotopic model of human non-small-cell lung cancer.
Neoplasms
Targeting and Microenvironment-Responsive Lipid Nanocarrier for the Enhancement of Tumor Cell Recognition and Therapeutic Efficiency.
Neoplasms
Targeting antitumor effect of rhTNF-? fusion protein mediated by matrix metalloproteinase-2.
Neoplasms
Targeting matrix metalloproteinases with novel diazepine substituted cinnamic acid derivatives: design, synthesis, in vitro and in silico studies.
Neoplasms
Targeting melanoma growth and metastasis with systemic delivery of liposome-incorporated protease-activated receptor-1 small interfering RNA.
Neoplasms
Targeting NF-?B mediated cell signaling pathway and inflammatory mediators by 1,2-diazole in A549 cells in vitro.
Neoplasms
Targeting of MMP2 activity in malignant tumors with a 68Ga-labeled gelatinase inhibitor cyclic peptide.
Neoplasms
Targeting of tumor blood vessels: a phage-displayed tumor-homing peptide specifically binds to matrix metalloproteinase-2-processed collagen IV and blocks angiogenesis in vivo.
Neoplasms
Targeting signaling pathways of VEGFR1 and VEGFR2 as a potential target in the treatment of breast cancer.
Neoplasms
Targeting surface nucleolin with a multivalent pseudopeptide delays development of spontaneous melanoma in RET transgenic mice.
Neoplasms
Targeting the MMP-14/MMP-2/integrin ?v?3 axis with multispecific N-TIMP2-based antagonists for cancer therapy.
Neoplasms
Targeting the molecular chaperone heat shock protein 90 (HSP90): Lessons learned and future directions.
Neoplasms
Targeting the Stat6 pathway in tumor-associated macrophages reduces tumor growth and metastatic niche formation in breast cancer.
Neoplasms
Targeting the tumor microenvironment with chemically modified tetracyclines: inhibition of laminin 5 gamma2 chain promigratory fragments and vasculogenic mimicry.
Neoplasms
Telmisartan Prevents Alveolar Bone Loss by Decreasing the Expression of Osteoclasts Markers in Hypertensive Rats With Periodontal Disease.
Neoplasms
Temozolomide does not influence the transcription or activity of matrix metalloproteinases 9 and 2 in glioma cell lines.
Neoplasms
Tetraspanin CD9 induces MMP-2 expression by activating p38 MAPK, JNK and c-Jun pathways in human melanoma cells.
Neoplasms
TGF-?1 facilitates MT1-MMP-mediated proMMP-9 activation and invasion in oral squamous cell carcinoma cells.
Neoplasms
TGF-beta enhances MMP-2 expression and activity through AKT in fibroblasts derived from angiofibromas in patients with tuberous sclerosis complex.
Neoplasms
TGF-beta-induced invasiveness of pancreatic cancer cells is mediated by matrix metalloproteinase-2 and the urokinase plasminogen activator system.
Neoplasms
TGFbeta1 regulation and collagen-release-independent connective tissue re-modelling by the ruthenium complex NAMI-A in solid tumours.
Neoplasms
Thalidomide decreases gelatinase production by malignant B lymphoid cell lines through disruption of multiple integrin-mediated signaling pathways.
Neoplasms
Thalidomide influences growth and vasculogenic mimicry channel formation in melanoma.
Neoplasms
The a3 Isoform Vacuolar Type H+-ATPase Promotes Distant Metastasis in the Mouse B16 Melanoma Cells.
Neoplasms
The absence of immunoreactivity for tissue inhibitor of metalloproteinase-1 (TIMP-1), but not for TIMP-2, protein is associated with a favorable prognosis in aggressive breast carcinoma.
Neoplasms
The activation of TLR7 regulates the expression of VEGF, TIMP1, MMP2, IL-6, and IL-15 in Hela cells.
Neoplasms
The activity of matrix metalloproteinases (MMPS) and tissue inhibitors of metalloproteinases (TIMPs) in mammary tumors of dogs and rats.
Neoplasms
The alpha 3 chain of type IV collagen prevents activation of human polymorphonuclear leukocytes.
Neoplasms
The anti-invasive role of novel synthesized pyridazine hydrazide appended phenoxy acetic acid against neoplastic development targeting matrix metallo proteases.
Neoplasms
The assessment of serum and diagnostic peritoneal lavage concentration of matrix metalloproteinase-2, matrix metalloproteinase-9, carbohydrate antigen 19-9, and carcinoembryonic antigen in patients with pancreatic cancer and chronic pancreatitis.
Neoplasms
The behavior of matrix metalloproteinases and their inhibitors in colorectal cancer.
Neoplasms
The behavior of MMP-2, MMP-7, MMP-9 and their inhibitors TIMP-1, TIMP-2 in adenoma-colorectal cancer sequence.
Neoplasms
The Biomarker TCONS_00016233 Drives Septic AKI by Targeting the miR-22-3p/AIFM1 Signaling Axis.
Neoplasms
The C3G/Rap1 pathway promotes secretion of MMP-2 and MMP-9 and is involved in serous ovarian cancer metastasis.
Neoplasms
The carboxyl terminal trimer of procollagen I induces pro-metastatic changes and vascularization in breast cancer cells xenografts.
Neoplasms
The CDK6-c-Jun-Sp1-MMP-2 axis as a biomarker and therapeutic target for triple-negative breast cancer.
Neoplasms
The clinical relevance of stromal matrix metalloproteinase expression in ovarian cancer.
Neoplasms
The cloning and expression of matrix metalloproteinase-2 and tissue inhibitor of matrix metalloproteinase 2 in normal canine lymph nodes and in canine lymphoma.
Neoplasms
The collagenase activities, interstitial collagenase and type IV collagenase, in human stomach cancer: with special reference to local spreading and lymph node metastasis.
Neoplasms
The combined use of EphA2/MMP-2 expression and MRI findings contributes to the determination of cerebral glioma grade.
Neoplasms
The correlation between immunohistochemical expression of MMP-2 and the prognosis of epithelial ovarian cancer.
Neoplasms
The crucial role of cyclooxygenase-2 in osteopontin-induced protein kinase C alpha/c-Src/IkappaB kinase alpha/beta-dependent prostate tumor progression and angiogenesis.
Neoplasms
The curcumin derivative WZ35 activates ROS-dependent JNK to suppress hepatocellular carcinoma metastasis.
Neoplasms
The Difference of Expression of 18 Genes in Axillary Invasion and Vascular Invasion Compared to Control Samples in Breast Cancer.
Neoplasms
The distribution of matrix metalloproteinases and tissue inhibitor of metalloproteinases in colorectal cancer.
Neoplasms
The effect of Candida albicans systemic infection on matrix metalloproteinases in breast cancer bearing BALB/c mice.
Neoplasms
The effect of dietary supplementation with limonene or myo-inositol on the induction of neoplasia and matrix metalloproteinase and plasminogen activator activities in accessory sex organs of male Lobund-Wistar rats.
Neoplasms
The effect of hypoxic microenvironment on matrix metalloproteinase expression in xenografts of human oral squamous cell carcinoma.
Neoplasms
The effect of intravascular interventional embolization and craniotomy on MMP-2, MMP-9 and caspase3 in serum of intracranial aneurysm patients.
Neoplasms
The effect of PI3K inhibitor LY294002 and gemcitabine hydrochloride combined with ionizing radiation on the formation of vasculogenic mimicry of Panc-1 cells in vitro and in vivo.
Neoplasms
The effect of platelets on invasiveness and protease production of human mammary tumor cells.
Neoplasms
The effect of probiotic yoghurt consumption on oxidative stress and inflammatory factors in young females after exhaustive exercise.
Neoplasms
The effect of sildenafil on right ventricular remodeling in a rat model of monocrotaline-induced right ventricular failure.
Neoplasms
The Effectiveness of Raloxifene-Loaded Liposomes and Cochleates in Breast Cancer Therapy.
Neoplasms
The effects of CoQ10 supplement on matrix metalloproteinases, oxidative DNA damage and pro-inflammatory cytokines in testicular ischaemia/reperfusion injury in rats.
Neoplasms
The effects of curcumin on the invasiveness of prostate cancer in vitro and in vivo.
Neoplasms
The effects of high-dose vitamin E supplementation on biomarkers of kidney injury, inflammation, and oxidative stress in patients with diabetic nephropathy: A randomized, double-blind, placebo-controlled trial.
Neoplasms
The effects of propofol on the growth behavior of hepatoma xenografts in Balb/c mice.
Neoplasms
The EGF signaling pathway influences cell migration and the secretion of metalloproteinases by myoepithelial cells in pleomorphic adenoma.
Neoplasms
The enzymatic processing of ?-dystroglycan by MMP-2 is controlled by two anchoring sites distinct from the active site.
Neoplasms
The estimation of metaloproteinases and their inhibitors blood levels in patients with pancreatic tumors.
Neoplasms
The ETS transcription factor MEF is a candidate tumor suppressor gene on the X chromosome.
Neoplasms
The Evaluation of AREG, MMP-2, CHI3L1, GFAP, and OPN Serum Combined Value in Astrocytic Glioma Patients' Diagnosis and Prognosis.
Neoplasms
The evolution of the matrix metalloproteinase inhibitor drug discovery program at abbott laboratories.
Neoplasms
The expression and activity of MMPs are increased in residual tumor tissues after the termination of immunotherapy.
Neoplasms
The expression and clinical significance of metastasis suppressor gene and matrix metalloproteinase-2 in esophageal squamous cell of carcinoma.
Neoplasms
The expression of apoptotic proteins and matrix metalloproteinases in odontogenic myxomas.
Neoplasms
The expression of matrix metalloproteinase-2 and -9 in human gliomas of different pathological grades.
Neoplasms
The expression of matrix metalloproteinases in intrahepatic cholangiocarcinoma, hilar (Klatskin tumor), middle and distal extrahepatic cholangiocarcinoma, gallbladder cancer, and ampullary carcinoma: role of matrix metalloproteinases in tumor progression and prognosis.
Neoplasms
The expression of metaloproteinases-2 and -9 is different according to the patterns of growth and invasion in squamous cell carcinoma of the penis.
Neoplasms
The expression of MMP-2 and Ki-67 in head and neck melanoma, and their correlation with clinic-pathologic indices.
Neoplasms
The expression of MMP-2 and TIMP-2 in patients with colorectal adenocarcinoma invaded to the submucosal and proper muscle layer.
Neoplasms
The favorable prognostic impact of tissue inhibitor of matrix metalloproteinases-1 protein overexpression in breast cancer cells.
Neoplasms
The flare-up reactions after systemic provocation in contact allergy to nickel and gold.
Neoplasms
The G(12) family proteins upregulate matrix metalloproteinase-2 via p53 leading to human breast cell invasion.
Neoplasms
The growth and metastasis of human hepatocellular carcinoma xenografts are inhibited by small interfering RNA targeting to the subunit ATP6L of proton pump.
Neoplasms
The herbal medicine Sho-saiko-to inhibits growth and metastasis of malignant melanoma primarily developed in ret-transgenic mice.
Neoplasms
The High Mobility Group A1 (HMGA1) gene is highly overexpressed in human uterine serous carcinomas and carcinosarcomas and drives Matrix Metalloproteinase-2 (MMP-2) in a subset of tumors.
Neoplasms
The Immunohistochemical Expression of STAT3, Bcl-xL, and MMP-2 Proteins in Colon Adenoma and Adenocarcinoma.
Neoplasms
The impact of a chlorotoxin-modified liposome system on receptor MMP-2 and the receptor-associated protein ClC-3.
Neoplasms
The In Ovo Chick Chorioallantoic Membrane (CAM) Assay as an Efficient Xenograft Model of Hepatocellular Carcinoma.
Neoplasms
The in vitro and in vivo anti-metastatic efficacy of oxythiamine and the possible mechanisms of action.
Neoplasms
The inhibitory mechanism of a novel cationic glucosamine derivative against MMP-2 and MMP-9 expressions.
Neoplasms
The initial steps of ovarian cancer cell metastasis are mediated by MMP-2 cleavage of vitronectin and fibronectin.
Neoplasms
The insulin-like growth factor-I receptor inhibitor picropodophyllin causes tumor regression and attenuates mechanisms involved in invasion of uveal melanoma cells.
Neoplasms
The interaction between aromatase, metalloproteinase 2,9 and cd44 in breast cancer.
Neoplasms
The invasiveness of human cervical cancer associated to the function of NaV1.6 channels is mediated by MMP-2 activity.
Neoplasms
The Ketogenic Diet Alters the Hypoxic Response and Affects Expression of Proteins Associated with Angiogenesis, Invasive Potential and Vascular Permeability in a Mouse Glioma Model.
Neoplasms
The laminin receptor and basement membrane dissolution: role in tumour metastasis.
Neoplasms
The levels of trypsinogen isoenzymes in ovarian tumour cyst fluids are associated with promatrix metalloproteinase-9 but not promatrix metalloproteinase-2 activation.
Neoplasms
The matrix metalloproteinase inhibitor batimastat (BB-94) retards human breast cancer solid tumor growth but not ascites formation in nude mice.
Neoplasms
The membrane-anchored MMP inhibitor RECK is a key regulator of extracellular matrix integrity and angiogenesis.
Neoplasms
The metallo-disintegrin ADAM10 (MADM) from bovine kidney has type IV collagenase activity in vitro.
Neoplasms
The Metastatic Microenvironment: Melanoma-Microglia Cross-Talk Promotes the Malignant Phenotype of Melanoma Cells.
Neoplasms
The mir-423-5p/MMP-2 Axis Regulates the Nerve Growth Factor-Induced Promotion of Chondrosarcoma Metastasis.
Neoplasms
The MMP-2 and MMP-9 promoter polymorphisms and susceptibility to salivary gland cancer.
Neoplasms
The multifaceted roles of neutrophil gelatinase associated lipocalin (NGAL) in inflammation and cancer.
Neoplasms
The multifunctional role of the immunohistochemical expression of MMP-7 in invasive breast cancer.
Neoplasms
The MyD88 inhibitor TJ-M2010-2 suppresses proliferation, migration and invasion of breast cancer cells by regulating MyD88/GSK-3? and MyD88/NF-?B signalling pathways.
Neoplasms
The p38 SAPK pathway regulates the expression of the MMP-9 collagenase via AP-1-dependent promoter activation.
Neoplasms
The phosphoinositide-binding protein ZF21 regulates ECM degradation by invadopodia.
Neoplasms
The prevalence of undiagnosed renal failure in a cohort of COPD patients in western Norway.
Neoplasms
The preventive and curative effects of melatonin against abdominal aortic aneurysm in rats.
Neoplasms
The pro-inflammatory peptide LL-37 promotes ovarian tumor progression through recruitment of multipotent mesenchymal stromal cells.
Neoplasms
The prognostic value of metalloproteinases and angiogenic factors in ovarian carcinoma.
Neoplasms
The prognostic value of the expression of collagenase IV, cathepsin D and metallothionein in squamous cell carcinomas of the skin determined by immunohistochemistry.
Neoplasms
The programmed site-specific delivery of the angiostatin sunitinib and chemotherapeutic paclitaxel for highly efficient tumor treatment.
Neoplasms
The protective role of the -1306C>T functional polymorphism in matrix metalloproteinase-2 gene is associated with cervical cancer: implication of human papillomavirus infection.
Neoplasms
The Protein Extract of Chlorella minutissima Inhibits The Expression of MMP-1, MMP-2 and MMP-9 in Cancer Cells through Upregulation of TIMP-3 and Down Regulation of c-Jun.
Neoplasms
The ratio of MMP-2 to TIMP-2 in hilar cholangiocarcinoma: a semi-quantitative study.
Neoplasms
The regulatory mechanism of extracellular Hsp90{alpha} on matrix metalloproteinase-2 (MMP-2) processing and tumor angiogenesis.
Neoplasms
The relation of gelatinase (MMP-2 and -9) expression with distant site metastasis and tumour aggressiveness in colorectal cancer.
Neoplasms
The relationship between endotoxemia and hepatic endocannabinoids in cirrhotic rats with portal hypertension.
Neoplasms
The relationship between MMP-2 and MMP-9 expression levels with breast cancer incidence and prognosis.
Neoplasms
The relevance and role of vascular endothelial growth factor C, matrix metalloproteinase-2 and E-cadherin in epithelial ovarian cancer.
Neoplasms
The role of extracellular matrix metalloproteinase inducer protein in prostate cancer progression.
Neoplasms
The role of inflammation in patients with intraductal mucinous neoplasm of the pancreas and in those with pancreatic adenocarcinoma.
Neoplasms
The role of matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) in the development of esophageal cancer.
Neoplasms
The role of matrix metalloproteinases in tumor angiogenesis and tumor metastasis.
Neoplasms
The role of MMP-2 and MMP-9 as prognostic markers in the early stages of tongue squamous cell carcinoma.
Neoplasms
The role of MMP-2 and MMP-9 in the metastasis and development of hypopharyngeal carcinoma.
Neoplasms
The Role of Oxidative Stress Markers in Predicting Acute Thrombotic Occlusion of Haemodialysis Vascular Access and Progressive Stenotic Dysfunction Demanding Angioplasty.
Neoplasms
The role of p53 protein and MMP-2 tumor/stromal cells expression on progressive growth of ovarian neoplasms.
Neoplasms
The role of serum response factor in hepatocellular carcinoma: An association with matrix metalloproteinase.
Neoplasms
The role of the activated form of matrix metalloproteinase-2 in urothelial cancer.
Neoplasms
The role of the Fas/FasL signaling pathway in environmental toxicant-induced testicular cell apoptosis: An update.
Neoplasms
The role of the IGF-I receptor in the regulation of matrix metalloproteinases, tumor invasion and metastasis.
Neoplasms
The significance of MMP-1 and MMP-2 in peritoneal disseminated metastasis of gastric cancer.
Neoplasms
The Significance of MMP-9 Over MMP-2 in HCC Invasiveness and Recurrence of Hepatocellular Carcinoma After Curative Resection.
Neoplasms
The site-dependent growth characteristics of a human xenotransplanted basaloid squamous cell carcinoma.
Neoplasms
The Target Differences of Anti-Tumorigenesis Potential of Curcumin and its Analogues Against HER-2 Positive and Triple-Negative Breast Cancer Cells.
Neoplasms
The Toll-like receptor adaptor proteins MyD88 and Mal/TIRAP contribute to the inflammatory and destructive processes in a human model of rheumatoid arthritis.
Neoplasms
The type I collagen induction of MT1-MMP-mediated MMP-2 activation is repressed by alphaVbeta3 integrin in human breast cancer cells.
Neoplasms
The upregulated ?-catulin expression was involved in head-neck squamous cell carcinogenesis by promoting proliferation, migration, invasion, and epithelial to mesenchymal transition.
Neoplasms
The use of EEM fluorescence data and OPLS/UPLS-DA algorithm to discriminate between normal and cancer cell lines: a feasibility study.
Neoplasms
Therapeutic effect of topical 5-fluorouracil in conjunctival squamous carcinoma is associated with changes in matrix metalloproteinases and tissue inhibitor of metalloproteinases expression.
Neoplasms
Therapeutic nanomedicine based on dual-intelligent functionalized gold nanoparticles for cancer imaging and therapy in vivo.
Neoplasms
Therapeutic potential of siRNA-mediated targeting of urokinase plasminogen activator, its receptor, and matrix metalloproteinases.
Neoplasms
Therapeutic targeting of oncogenic transforming growth factor-?1 signaling by antisense oligonucleotides in oral squamous cell carcinoma.
Neoplasms
Therapy of head and neck squamous cell carcinoma with replicative adenovirus expressing tissue inhibitor of metalloproteinase-2 and chemoradiation.
Neoplasms
Thrombin-thrombomodulin activation of protein C facilitates the activation of progelatinase A.
Neoplasms
Thrombospondin-4 promotes bladder cancer cell migration and invasion via MMP2 production.
Neoplasms
Thrombospondins, metallo proteases and thrombospondin receptors messenger RNA and protein expression in different tumour sublines of the Dunning prostate cancer model.
Neoplasms
Tideglusib induces apoptosis in human neuroblastoma IMR32 cells, provoking sub-G0/G1 accumulation and ROS generation.
Neoplasms
Tight junction defects are seen in the buccal mucosa of patients receiving standard dose chemotherapy for cancer.
Neoplasms
Tight junction protein claudin-1 enhances the invasive activity of oral squamous cell carcinoma cells by promoting cleavage of laminin-5 gamma2 chain via matrix metalloproteinase (MMP)-2 and membrane-type MMP-1.
Neoplasms
TIMP-1 expression in anaplastic large cell lymphoma is usually restricted to macrophages and only seldom observed in tumour cells.
Neoplasms
TIMP-1 induces an EMT-like phenotypic conversion in MDCK cells independent of its MMP-inhibitory domain.
Neoplasms
TIMP-1 overexpression in pancreatic cancer attenuates tumor growth, decreases implantation and metastasis, and inhibits angiogenesis.
Neoplasms
TIMP-2 fusion protein with human serum albumin potentiates anti-angiogenesis-mediated inhibition of tumor growth by suppressing MMP-2 expression.
Neoplasms
TIMP-2 gene rs4789936 polymorphism is associated with increased risk of breast cancer and poor prognosis in Southern Chinese women.
Neoplasms
Timp3 loss accelerates tumour invasion and increases prostate inflammation in a mouse model of prostate cancer.
Neoplasms
Tissue and circulating immunoreactive protein for MMP-2 and TIMP-2 in head and neck squamous cell carcinoma-tissue immunoreactivity predicts aggressive clinical course.
Neoplasms
Tissue and serum metalloproteinase (MMP-2) expression in advanced ovarian serous cystoadenocarcinomas: clinical and prognostic implications.
Neoplasms
Tissue and serum mRNA profile of MMPs-2/9 as a potential novel biomarker for the most individual approach in infantile hemangiomas and cancer disease.
Neoplasms
Tissue distribution of major matrix metalloproteinases and their transcripts in human breast carcinomas.
Neoplasms
Tissue inhibitor of metalloproteinase 3 suppresses tumor angiogenesis in matrix metalloproteinase 2-down-regulated lung cancer.
Neoplasms
Tissue inhibitor of metalloproteinase-2 protection of matrix metalloproteinase-2 from degradation by plasmin is reversed by divalent cation chelator EDTA and the bisphosphonate alendronate.
Neoplasms
Tissue inhibitor of metalloproteinase-2 regulates matrix metalloproteinase-2-mediated endothelial barrier dysfunction and breast cancer cell transmigration through lung microvascular endothelial cells.
Neoplasms
Tissue inhibitor of metalloproteinase-3 expression from an oncolytic adenovirus inhibits matrix metalloproteinase activity in vivo without affecting antitumor efficacy in malignant glioma.
Neoplasms
Tissue inhibitor of metalloproteinases-1 (TIMP-1) RNA is expressed at elevated levels in malignant non-Hodgkin's lymphomas.
Neoplasms
Tissue inhibitor of metalloproteinases-4 inhibits but does not support the activation of gelatinase A via efficient inhibition of membrane type 1-matrix metalloproteinase.
Neoplasms
Tissue MMP-2 and MMP-9 [corrected] are better prognostic factors than serum MMP-2/TIMP-2--complex or TIMP-1 [corrected] in stage [corrected] I-III lung carcinoma.
Neoplasms
Tissue transglutaminase regulates MMP-2 in ovarian cancer by modulating CREB activity.
Neoplasms
TLX activates MMP-2, promotes self-renewal of tumor spheres in neuroblastoma and correlates with poor patient survival.
Neoplasms
TMEFF2 inhibits pancreatic cancer cells proliferation, migration, and invasion by suppressing phosphorylation of the MAPK signaling pathway.
Neoplasms
TNF-? inhibition decreases MMP-2 activity, reactive oxygen species formation and improves hypertensive vascular hypertrophy independent of its effects on blood pressure.
Neoplasms
Tocilizumab inhibits interleukin-6-mediated matrix metalloproteinase-2 and -9 secretions from human amnion cells in preterm premature rupture of membranes.
Neoplasms
Toll-Like Receptor 3 Deficiency Leads to Altered Immune Responses to Chlamydia trachomatis Infection in Human Oviduct Epithelial Cells.
Neoplasms
Toll-like receptor 4 mediates inflammatory cytokine secretion in smooth muscle cells induced by oxidized low-density lipoprotein.
Neoplasms
Toll-like receptor 4 mediates maladaptive left ventricular remodeling and impairs cardiac function after myocardial infarction.
Neoplasms
Tomatidine inhibits cell invasion through the negative modulation of gelatinase and inactivation of p38 and ERK.
Neoplasms
Topical application of recombinant platelet-derived growth factor increases the rate of healing and the level of proteins that regulate this response.
Neoplasms
Towards prostate cancer gene therapy: Development of a chlorotoxin-targeted nanovector for toxic (melittin) gene delivery.
Neoplasms
TRAIL inhibits angiogenesis stimulated by VEGF expression in human glioblastoma cells.
Neoplasms
Transcription repressor slug promotes carcinoma invasion and predicts outcome of patients with lung adenocarcinoma.
Neoplasms
Transcriptional activation by p53 of the human type IV collagenase (gelatinase A or matrix metalloproteinase 2) promoter.
Neoplasms
Transcriptional expression of the genes implicated in angiogenesis and tumor invasion in cervical carcinomas.
Neoplasms
Transcriptional Factors for Epithelial-Mesenchymal Transition Are Associated with Mesenchymal Differentiation in Gliosarcoma.
Neoplasms
Transcriptional suppression of matrix metalloproteinase-2 gene expression in human astroglioma cells by TNF-alpha and IFN-gamma.
Neoplasms
Transcutaneous carbon dioxide induces mitochondrial apoptosis and suppresses metastasis of oral squamous cell carcinoma in vivo.
Neoplasms
Transfection of nm23-H1 increased expression of beta-Catenin, E-Cadherin and TIMP-1 and decreased the expression of MMP-2, CD44v6 and VEGF and inhibited the metastatic potential of human non-small cell lung cancer cell line L9981.
Neoplasms
Transformation-specific matrix metalloproteinases, MMP-7 and MMP-13, are present in epithelial cells of keratoacanthomas.
Neoplasms
Transforming growth factor beta 1 regulation of metalloproteinase production in cultured human cervical epithelial cells.
Neoplasms
Transforming growth factor beta receptor type II inactivation induces the malignant transformation of intestinal neoplasms initiated by Apc mutation.
Neoplasms
Transforming growth factor beta1 stimulates contrasting responses in metastatic versus primary mouse prostate cancer-derived cell lines in vitro.
Neoplasms
Transforming growth factor-β and matrix metalloproteinase secretion in cell culture from ex-vivo pbmc after exposure to uv radiation.
Neoplasms
Transforming growth factor-?1 suppresses the up-regulation of matrix metalloproteinase-2 by lung fibroblasts in response to tumor necrosis factor-?.
Neoplasms
Transforming growth factor-beta1 modulates metalloproteinase-2 and -9, nitric oxide, RhoA and alpha-smooth muscle actin expression in colon adenocarcinoma cells.
Neoplasms
Transglutaminase-2 Is Involved in All-Trans Retinoic Acid-Induced Invasion and Matrix Metalloproteinases Expression of SH-SY5Y Neuroblastoma Cells via NF-?B Pathway.
Neoplasms
Treatment of colorectal liver metastases by adenoviral transfer of tissue inhibitor of metalloproteinases-2 into the liver tissue.
Neoplasms
Treatment of epigallocatechin-3-gallate inhibits matrix metalloproteinases-2 and -9 via inhibition of activation of mitogen-activated protein kinases, c-jun and NF-kappaB in human prostate carcinoma DU-145 cells.
Neoplasms
Treatment with granulocyte colony-stimulating factor ameliorates chronic heart failure.
Neoplasms
Treatment with halofuginone results in marked growth inhibition of a von Hippel-Lindau pheochromocytoma in vivo.
Neoplasms
Trichostatin A-histone deacetylase inhibitor with clinical therapeutic potential-is also a selective and potent inhibitor of gelatinase A expression.
Neoplasms
Tricolor imaging of MMPs to investigate the promoting roles of inflammation on invasion and migration of tumor cells.
Neoplasms
Triptolide sensitizes cisplatin-resistant human epithelial ovarian cancer by inhibiting the phosphorylation of AKT.
Neoplasms
Tumor Cell Invasion Induced by Radiation in Balb/C Mouse is Prevented by the Cox-2 Inhibitor NS-398.
Neoplasms
Tumor cell invasion through matrigel is regulated by activated matrix metalloproteinase-2.
Neoplasms
Tumor cell specific expression of MMP-2 correlates with tumor vascularisation in breast cancer.
Neoplasms
Tumor cell surface-associated binding site for the M(r) 72,000 type IV collagenase.
Neoplasms
Tumor cell-derived collagenase-stimulatory factor increases expression of interstitial collagenase, stromelysin, and 72-kDa gelatinase.
Neoplasms
Tumor characteristics involved in the metastatic behaviour as an improvement in primary cutaneous melanoma prognostics.
Neoplasms
Tumor collagenase stimulatory factor (TCSF) expression and localization in human lung and breast cancers.
Neoplasms
Tumor delivery efficiency and apoptosis enhancement by EVO nanoparticles on murie hepatic carcinoma cell line H22.
Neoplasms
Tumor gelatinases and invasion inhibited by the green tea flavanol epigallocatechin-3-gallate.
Neoplasms
Tumor grade and matrix metalloproteinase 2 expression in stromal fibroblasts help to stratify the high-risk group of patients with early breast cancer identified on the basis of st gallen recommendations.
Neoplasms
Tumor marker potential of serum matrix metalloproteinases in patients with head and neck cancer.
Neoplasms
Tumor metastasis in an orthotopic murine model of head and neck cancer: possible role of TGF-beta 1 secreted by the tumor cells.
Neoplasms
Tumor microenvironment triple-responsive nanoparticles enable enhanced tumor penetration and synergetic chemo-photodynamic therapy.
Neoplasms
Tumor necrosis factor ?, protein gene product 9.5, matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 presence in congenital intra-abdominal adhesions in children under one year of age.
Neoplasms
Tumor necrosis factor alpha and lymphotoxin stimulate human myeloblastic leukemia cell (ML-1) invasion through a reconstituted basement membrane (Matrigel) with concomitant induction of 92 kDa gelatinase secretion.
Neoplasms
Tumor necrosis factor stimulates gelatinase and collagenase production by granulation tissue in culture.
Neoplasms
Tumor necrosis factor-? regulates matrix metalloproteinase-2 expression and cell migration via ERK pathway in rat glomerular mesangial cells.
Neoplasms
Tumor paint: a chlorotoxin:Cy5.5 bioconjugate for intraoperative visualization of cancer foci.
Neoplasms
Tumor progression and expression of matrix metalloproteinase-2 (MMP-2) mRNA by human urinary bladder cancer cells.
Neoplasms
Tumor progression driven by pathways activating matrix metalloproteinases and their inhibitors.
Neoplasms
Tumor promoter-stimulated Mr 92,000 gelatinase secreted by normal and malignant human cells: isolation and characterization of the enzyme from HT1080 tumor cells.
Neoplasms
Tumor suppressor HLJ1 binds and functionally alters nucleophosmin via activating enhancer binding protein 2alpha complex formation.
Neoplasms
Tumor targeted gold nanoparticles for FRET-based tumor imaging and light responsive on-demand drug release.
Neoplasms
Tumor-Associated Fibroblast-Targeted Regulation and Deep Tumor Delivery of Chemotherapeutic Drugs with a Multifunctional Size-Switchable Nanoparticle.
Neoplasms
Tumor-associated proteases and inhibitors in gastric cancer: analysis of prognostic impact and individual risk protease patterns.
Neoplasms
Tumor-derived tumor necrosis factor-alpha promotes progression and epithelial-mesenchymal transition in renal cell carcinoma cells.
Neoplasms
Tumor-elicited polymorphonuclear cells, in contrast to "normal" circulating polymorphonuclear cells, stimulate invasive and metastatic potentials of rat mammary adenocarcinoma cells.
Neoplasms
Tumor-specific urinary matrix metalloproteinase fingerprinting: identification of high molecular weight urinary matrix metalloproteinase species.
Neoplasms
Tumor-stroma interaction: positive feedback regulation of extracellular matrix metalloproteinase inducer (EMMPRIN) expression and matrix metalloproteinase-dependent generation of soluble EMMPRIN.
Neoplasms
Tumor-suppressive function of long noncoding RNA MALAT1 in glioma cells by downregulation of MMP2 and inactivation of ERK/MAPK signaling.
Neoplasms
Tumor-targeted drug delivery and sensitization by MMP2-responsive polymeric micelles.
Neoplasms
Tumor-targeting and microenvironment-responsive smart nanoparticles for combination therapy of antiangiogenesis and apoptosis.
Neoplasms
Tumor-Triggered Disassembly of a Multiple-Agent-Therapy Probe for Efficient Cellular Internalization.
Neoplasms
Tumor-triggered transformation of chimeric peptide for dual-stage-amplified magnetic resonance imaging and precise photodynamic therapy.
Neoplasms
Tumoral and macrophage uPAR and MMP-9 contribute to the invasiveness of B16 murine melanoma cells.
Neoplasms
Tumoral and stromal expression of MMP-2, MMP-9, MMP-14, TIMP-1, TIMP-2, and VEGF-A in cervical cancer patient survival: a competing risk analysis.
Neoplasms
Tumour metastasis suppressor, nm23-beta, inhibits gelatinase A transcription by interference with transactivator Y-box protein-1 (YB-1).
Neoplasms
Tumour necrosis factor alpha up-regulates matrix metalloproteinase-2 activity in periovulatory ovine follicles: metamorphic and endocrine implications.
Neoplasms
Tumour Necrosis Factor-alpha and Matrix Metalloproteinase-2 are Expressed Strongly in Hidradenitis Suppurativa.
Neoplasms
Tumour-associated fibrinolysis: the prognostic relevance of plasminogen activators uPA and tPA in human breast cancer.
Neoplasms
Two-stage activated nano-truck enhanced specific aggregation and deep delivery for synergistic tumor ablation.
Neoplasms
Type 1 insulin-like growth factor regulates MT1-MMP synthesis and tumor invasion via PI 3-kinase/Akt signaling.
Neoplasms
Type I collagen-induced pro-MMP-2 activation is differentially regulated by H-Ras and N-Ras in human breast epithelial cells.
Neoplasms
Type IV collagen induces matrix metalloproteinase 2 activation in HT1080 fibrosarcoma cells.
Neoplasms
Type IV collagen, type IV collagenase activity and ability of cell proliferation in human thyroid tumours.
Neoplasms
Type IV collagenase (M(r) 72,000) expression in human prostate: benign and malignant tissue.
Neoplasms
Type IV collagenase activity and cavernous sinus invasion in human pituitary adenomas.
Neoplasms
Type IV collagenase activity of a primary HSV-2-induced hamster fibrosarcoma and its in vivo metastases and in vitro clones.
Neoplasms
Type IV collagenase and immunostaining of type IV collagen in human thyroid tumors.
Neoplasms
Type IV collagenase/gelatinase (MMP-2) is not increased in plasma of patients with cancer.
Neoplasms
Ulex europaeus I lectin induces activation of matrix-metalloproteinase-2 in endothelial cells.
Neoplasms
Ultraviolet radiation-induced inflammation activates ?-catenin signaling in mouse skin and skin tumors.
Neoplasms
Up-regulation of angiopoietin-2, matrix metalloprotease-2, membrane type 1 metalloprotease, and laminin 5 gamma 2 correlates with the invasiveness of human glioma.
Neoplasms
Up-regulation of CD147 and matrix metalloproteinase-2, -9 induced by P-glycoprotein substrates in multidrug resistant breast cancer cells.
Neoplasms
Upregulated EMMPRIN/CD147 might contribute to growth and angiogenesis of gastric carcinoma: a good marker for local invasion and prognosis.
Neoplasms
Upregulation of matrix metalloproteinases (MMPs) in breast cancer xenografts: a major induction of stromal MMP-13.
Neoplasms
Upregulation of miR-328 and inhibition of CREB-DNA-binding activity are critical for resveratrol-mediated suppression of matrix metalloproteinase-2 and subsequent metastatic ability in human osteosarcomas.
Neoplasms
Upregulation of MMP-2 by HMGA1 promotes transformation in undifferentiated, large-cell lung cancer.
Neoplasms
Upregulation of tissue inhibitor of metalloproteinases (TIMP)-2 promotes matrix metalloproteinase (MMP)-2 activation and cell invasion in a human glioblastoma cell line.
Neoplasms
Urinary release of 72 and 92 kDa gelatinases, TIMPs, N-GAL and conventional prognostic factors in urothelial carcinomas.
Neoplasms
Use of plasma MMP-2 and MMP-9 levels as a surrogate for tumour expression in colorectal cancer patients.
Neoplasms
Usefulness of VEGF, MMP-2, MMP-3 and TIMP-2 serum level evaluation in patients with adrenal tumours.
Neoplasms
Using caffeoyl pyrrolidine derivative LY52, a potential inhibitor of matrix metalloproteinase-2, to suppress tumor invasion and metastasis.
Neoplasms
Vascular cell adhesion molecule-1-mediated matrix metalloproteinase-2 induction in peripheral blood T cells is up-regulated in patients with HTLV-I-associated myelopathy.
Neoplasms
Vascular endothelial growth factor activating matrix metalloproteinase in ascitic fluid during peritoneal dissemination of ovarian cancer.
Neoplasms
Vascular endothelial growth factor expression in the basal subtype of breast carcinoma.
Neoplasms
Vascular endothelial growth factor induces tissue factor and matrix metalloproteinase production in endothelial cells: conversion of prothrombin to thrombin results in progelatinase A activation and cell proliferation.
Neoplasms
Vascular endothelial growth factor stimulates organ-specific host matrix metalloproteinase-9 expression and ovarian cancer invasion.
Neoplasms
Vascular matrix metalloproteinase-2 cleaves big endothelin-1 yielding a novel vasoconstrictor.
Neoplasms
Vasculogenic mimicry is a major feature and novel predictor of poor prognosis in patients with orbital rhabdomyosarcoma.
Neoplasms
Vasoactive intestinal peptide ameliorates synovial cell functions of collagen-induced arthritis rats by down-regulating NF-kappaB activity.
Neoplasms
VEGF release by MMP-9 mediated heparan sulphate cleavage induces colorectal cancer angiogenesis.
Neoplasms
VEGF-D-enhanced lymph node metastasis of ovarian cancer is reversed by vesicular stomatitis virus matrix protein.
Neoplasms
VEGFR-2 kinase domain inhibition as a scaffold for anti-angiogenesis: Validation of the anti-angiogenic effects of carotenoids from Spondias mombin in DMBA model of breast carcinoma in Wistar rats.
Neoplasms
Vemurafenib resistance increases melanoma invasiveness and modulates the tumor microenvironment by MMP-2 upregulation.
Neoplasms
Verbascoside Inhibits Glioblastoma Cell Proliferation, Migration and Invasion While Promoting Apoptosis Through Upregulation of Protein Tyrosine Phosphatase SHP-1 and Inhibition of STAT3 Phosphorylation.
Neoplasms
Vernolide-A inhibits radiation-induced hypoxia-mediated tumor angiogenesis by regulating HIF-1?, MMP-2, MMP-9, and VEGF.
Neoplasms
Versatile Functionalization of Poly(methacrylic acid) Brushes with Series of Proteolytically Cleavable Peptides for Highly Sensitive Protease Assay.
Neoplasms
Video-rate bioluminescence imaging of matrix metalloproteinase-2 secreted from a migrating cell.
Neoplasms
Vinorelbine cationic liposomes modified with wheat germ agglutinin for inhibiting tumor metastasis in treatment of brain glioma.
Neoplasms
Violacein inhibits matrix metalloproteinase mediated CXCR4 expression: potential anti-tumor effect in cancer invasion and metastasis.
Neoplasms
Visualization of MMP-2 Activity Using Dual-Probe Nanoparticles to Detect Potential Metastatic Cancer Cells.
Neoplasms
Vitamin D, tamoxifen and beta-estradiol modulate breast cancer cell growth and interleukin-6 and metalloproteinase-2 production in three-dimensional co-cultures of tumor cell spheroids with endothelium.
Neoplasms
Walker 256 cancer cells secrete tissue inhibitor of metalloproteinase-free metalloproteinase-9.
Neoplasms
Walker 256 tumor cell degradation of extracellular matrices involves a latent gelatinase activated by reactive oxygen species.
Neoplasms
WFDC2 contributes to epithelial-mesenchymal transition (EMT) by activating AKT signaling pathway and regulating MMP-2 expression.
Neoplasms
What structure and function of avian plasminogen activator and matrix metalloproteinase-2 reveal about their counterpart mammalian enzymes, their regulation and their role in tumor invasion.
Neoplasms
Wnt signaling pathway inhibitors as promising diagnostic serum markers of osteolytic bone metastasis.
Neoplasms
Worse prognosis in breast cancer patients can be predicted by immunohistochemical analysis of positive MMP-2 and negative estrogen and progesterone receptors.
Neoplasms
Wound-healing Activity of Zanthoxylum bungeanum Maxim Seed Oil on Experimentally Burned Rats.
Neoplasms
ZD4054, a specific antagonist of the endothelin A receptor, inhibits tumor growth and enhances paclitaxel activity in human ovarian carcinoma in vitro and in vivo.
Neoplasms
Zerumbone suppresses the motility and tumorigenecity of triple negative breast cancer cells via the inhibition of TGF-?1 signaling pathway.
Neoplasms
Zinc deprivation promotes progression of 1,2-dimethylhydrazine-induced colon tumors but reduces malignant invasion in mice.
Neoplasms
Zinc supplementation attenuates ethanol- and acetaldehyde-induced liver stellate cell activation by inhibiting reactive oxygen species (ROS) production and by influencing intracellular signaling.
Neoplasms
Zingerone suppresses angiogenesis via inhibition of matrix metalloproteinases during tumor development.
Neoplasms
Zn(2+) induces apoptosis in human highly metastatic SHG-44 glioma cells, through inhibiting activity of the voltage-gated proton channel Hv1.
Neoplasms
ZNF139 promotes tumor metastasis by increasing migration and invasion in human gastric cancer cells.
Neoplasms
Zoledronate is a potent inhibitor of myeloma cell growth and secretion of IL-6 and MMP-1 by the tumoral environment.
Neoplasms
Zoledronic-acid-induced circulating level modifications of angiogenic factors, metalloproteinases and proinflammatory cytokines in metastatic breast cancer patients.
Neoplasms
Zymographic analysis of circulating and tissue forms of colon carcinoma gelatinase A (MMP-2) and B (MMP-9) separated by mono- and two-dimensional electrophoresis.
Neoplasms
Zymographic detection and clinical correlations of MMP-2 and MMP-9 in breast cancer sera.
Neoplasms
[4-acetamidophenyl retinoate (4-APR) inhibits reconstituted basement membrane invasion by tumor cells and its mechanism]
Neoplasms
[A study on the correlation between the activity of 72,000 type IV collagenase and the metastatic potential of cancer cells]
Neoplasms
[An experimental research on tumor metastasis treated by chicken homologous matrix metalloproteinase-2 vaccine combined with low-dose cisplatin]
Neoplasms
[Anti-human collagenase type IV expression in preneoplastic lesions and early squamous cell lung carcinoma]
Neoplasms
[Anti-sense nucleic acid of CyclinD1 induces apoptosis of lung adenocarcinoma cancer cell A549.]
Neoplasms
[Assay of matrix metalloproteinase levels and their endogenous inhibitors in patients with laryngeal carcinoma]
Neoplasms
[Association of JMJD3, MMP-2 and VEGF expressions with clinicopathological features of invasive ductal breast carcinoma].
Neoplasms
[Bcl-2 associated athanogene 3 affects the epithelial-mesenchymal transition in human cervical cancer].
Neoplasms
[CD147 increases invasiveness of U937 cells through regulation of matrix metalloproteinase activity]
Neoplasms
[Characteristics and in vitro imaging study of matrix metalloproteinase-2 targeting activable cell-penetrating peptide]
Neoplasms
[Clinical and prognostic significance of tumor-associated proteases in gynecologic oncology]
Neoplasms
[Clinical significance and relationship of expression of matrix metalloproteinase-2 mRNA with breast cancer metastasis.]
Neoplasms
[Clinical significance of matrix metalloproteinase-2 expression in patients with epithelial ovarian tumor]
Neoplasms
[Clinicopathological significance of expressions of RECK and MMP-2 in esophageal squamous carcinoma]
Neoplasms
[Comparative study of mRNA expression of E-cadherin and collagenase IV in early and advanced cancers]
Neoplasms
[Constructing the tumor cell vaccine based on homologous matrix metalloproteinase-2 and exploring its effects]
Neoplasms
[Construction and secretory expression of single-chain Fv fragment M97 with therapeutic potential against tumor invasion and metastasis]
Neoplasms
[Correlation between expression of matrix metalloproteinase-2 and angiogenesis in esophageal carcinoma]
Neoplasms
[Correlation between expression of metastasis-related genes and lymph node metastasis in testicular cancer]
Neoplasms
[Correlation between expression of MMP-2, MMP-9, TIMP-2, TIMP-1 and metastasis of neuroblastoma]
Neoplasms
[Correlation between expressions of matrix metalloproteinase-2 & 9 and vasculogenic mimicry in gastrointestinal stromal tumors]
Neoplasms
[Correlation between matrix metalloproteinases-2 and tissue inhibitor of metalloproteinase-2 expression, metastatic potential and tumor angiogenesis in synovial sarcoma and its prognostic significance]
Neoplasms
[Correlation between MMP-2 activation and MT1-MMP mRNA expression in thymic epithelial tumors]
Neoplasms
[Correlation between the biological behavior and invasion potential in three mouse melanoma cell lines]
Neoplasms
[Correlation of expression of vascular endothelial growth factor and matrix matalloproteinase-2 to invasion of ovarian tumor cells in vitro]
Neoplasms
[Correlation of MUC1 expression to adhesion of breast cancer cell line MDA-MB-231.]
Neoplasms
[Correlations of serous levels of matrix metalloproteinases (MMP-2 and MMP-9) to invasion and metastasis of papillary thyroid carcinoma]
Neoplasms
[Effect of anticancer drugs on invasive capacity of human small-cell lung cancer cells in vitro]
Neoplasms
[Effect of As(2)O(3) on Expressions of COX-2 and Matrix Metalloproteinases in SGC7901 and K562 Cells.]
Neoplasms
[Effect of bone morphogenetic protein-2 on the expression of membrane Type 1-matrix metalloproteinase in human A549 lung carcinoma cells]
Neoplasms
[Effect of cyclooxygenase-2,and matrix metalloproteinase-2 expression on prognosis of lung cancer]
Neoplasms
[Effect of decidual cell conditioned media on invasion-related gene expression of ovarian tumor cell line COC1]
Neoplasms
[Effect of epigallocatechin-3-gallate on the invasiveness of hepatocarcinoma cells in vitro]
Neoplasms
[Effect of human bone marrow mesenchymal stem cells on invasion of tongue squamous cell carcinoma cell line Cal-27].
Neoplasms
[Effect of hypoxia on production and secretion of matrix metalloproteinases in tumor cells]
Neoplasms
[Effects of c9, t11-conjugated linoleic acid on the metastasis of human gastric carcinoma cell line]
Neoplasms
[Effects of focal adhesional kinase signaling on TNF-? induced gelatinases activity in cornea epithelium].
Neoplasms
[Effects of recombinant human endostatin and docetaxel on MMP and its following anti-neoplastic effect under different administration sequences]
Neoplasms
[Elevated expression of matrix metalloproteinase-9, and fibronectin concentration in recurrent epithelial ovarian cancer]
Neoplasms
[Establishment and characterization of a new human renal cell carcinoma cell line (KG-2) and metastatic model in nude mice]
Neoplasms
[Experimental study on mechanism of shugan qingzhi granule for stabilizing or reducing the plaque of atherosclerosis]
Neoplasms
[Expression and clinical impact of vascular endothelial growth factor and matrix metalloproteinase-2 in hepatocellular carcinoma]
Neoplasms
[Expression and clinical significance of kisspeptin-1, matrix metalloproteinase-2 and vascular endothelial growth factor in tissue of colon cancer].
Neoplasms
[Expression and clinical significance of matrix metalloproteinase in gastric stromal tumor]
Neoplasms
[Expression and clinical significance of MMP-2, MMP-9,TIMP-1, and TIMP-2 in breast carcinoma]
Neoplasms
[Expression and pathological mechanism of MMP-9 and HIF-2? in CD133(+) lung cancer stem cells].
Neoplasms
[Expression and significance of matrix metalloproteinases and their tissue inhibitors in the infiltration and metastasis of lung cancer.]
Neoplasms
[Expression and significance of tumor necrosis factor alpha, matrix metalloproteinase 2 and collagen in skin tissue of pressure ulcer of rats].
Neoplasms
[Expression of CD147 and MMP-2 in human gliomas and its correlations with prognosis]
Neoplasms
[Expression of CD147, matrix metalloproteinases and transforming growth factor beta1 in breast cancer]
Neoplasms
[Expression of FOXC-2 and YB-1 in Gastric Carcinoma and Its Role in Invasion and Metastasis].
Neoplasms
[Expression of LOX and MMP-2 in gastric cancer tissue and the effects of LOX and MMP-2 on tumor invasion and metastasis].
Neoplasms
[Expression of matrix metalloproteinase (MMP-2) and extracellular matrix metalloproteinases inducer (EMMPRIN) in benign and advanced breast cancer tissue samples]
Neoplasms
[Expression of matrix metalloproteinase-2 and insulin-like growth factor-1 in gastric carcinoma and their clinicopathological significance].
Neoplasms
[Expression of matrix metalloproteinase-2, 9 and it's tissue inhibitor-1, 2 in endometrial carcinoma]
Neoplasms
[Expression of matrix metalloproteinase-2, 9 and their inhibitor-TIMP 1,2 in human squamous cell carcinoma of uterine cervix]
Neoplasms
[Expression of matrix metalloproteinase-2,matrix metalloproteinase-9 and vascular endothdial growth factor in retinoblastoma and its clinical significance.]
Neoplasms
[Expression of matrix metalloproteinases 2 and 9 and their tissue inhibitors 1 and 2 in papillary thyroid cancer: an association with the clinical, morphological and ultrastructural characteristics of a tumor].
Neoplasms
[Expression of matrix metalloproteinases and tissue inhibitor of metalloproteinase in ameloblastoma]
Neoplasms
[Expression of matrix metalloproteinases and tissue inhibitor of metalloproteinases in colorectal neoplasm]
Neoplasms
[Expression of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases in the hepatocellular carcinomas]
Neoplasms
[Expression of matrix metalloproteinases in lung tissue and levels of some cytokines in bronchoalveolar lavage fluid in the obstructive emphysema rat models]
Neoplasms
[Expression of matrix metalloproteinases in metastatic lesions of cutaneous squamous cell carcinoma]
Neoplasms
[Expression of membrane-type I matrix metalloproteinase and its correlation with gelatinase A activation in cancer cell lines]
Neoplasms
[Expression of membrane-type matrix metalloproteinase (MT-MMP) and activation of MMP-2 in lung cancer]
Neoplasms
[Expression of MMP-2 and MMP-9 in non-small-cell lung cancer and their prognostic value.]
Neoplasms
[Expression of nm23/NDPK, integrin, type IV collagenase and uPA in transplanted tumors with various metastatic potential in nude mice and surgical specimens]
Neoplasms
[Expression of tumor matrix markers rebuild in laryngeal cancer depends on number of smoked cigarettes].
Neoplasms
[Expressions of CD147 and matrix metalloproteinase-2 in breast cancer and their correlations to prognosis]
Neoplasms
[Expressions of CD147, MMP-2 and MMP-9 in laryngeal carcinoma and clinical significance]
Neoplasms
[Expressions of inflammatory and fibrogenic factors in perinephric and subcutaneous adipose tissues of patients with adrenocorticotropic hormone-independent Cushing's syndrome].
Neoplasms
[Expressions of MMP-2 and COX-2 mRNA in bladder transitional cell carcinoma and their correlation]
Neoplasms
[Expressions of vascular endothelial growth factor C and matrix metalloproteinases-2 and prognosis of non-small cell lung carcinoma.]
Neoplasms
[Functions of neutrophil gelatinase-associated lipocalin in the esophageal carcinoma cell line SHEEC]
Neoplasms
[Gelatinases A and B and their endogenous regulators in the corpus uteri in squamous cell cervical carcinoma].
Neoplasms
[High tumorigenicity of human acute monocytic leukemic cell Line SHI-1 in nude mice and its mechanism]
Neoplasms
[Imaging of biological character of cancer using positron emission tomography(PET)]
Neoplasms
[Immunohistochemistry of matrix metalloproteinases in different morphologic types of the lung cancer developed in the inhabitants of the Semipalatinsk Region]
Neoplasms
[Immunoscintigraphy of anti-type IV collagenase monoclonal antibody in nude mice bearing human lung cancer xenograft]
Neoplasms
[Impacts of atovastatin and tinidazole on cardiac muscle inflammation factors of tumor necrosis factor-?, interleukin-1 and metalloproteinase-2 of experimental rabbits with atherosclerosis and periodontitis].
Neoplasms
[Increased cell migration of nasopharyngeal carcinoma cell lines in vitro by macrophage migration inhibitory factor]
Neoplasms
[Increased expression of gelatinases A and B, matrilysin and TIMP-1 genes in human malignant gliomas ]
Neoplasms
[Inhibition of human gastric cancer metastasis by ocreotide in vitro and in vivo]
Neoplasms
[Inhibition of tumor invasion by new retinoid, 5-4A, and its mechanism of the action]
Neoplasms
[Inhibitory effect of anti-type IV collagenase intrabody on invasiveness of human pulmonary giant cell carcinoma PG cells in vitro]
Neoplasms
[Inhibitory effect of endoplasmic reticulum-retained anti-type IV collagenase intrabody on invasion and proliferation of cancer cell]
Neoplasms
[Inhibitory effect of recombinant anti-angiogenic peptide of tumstatin on growth and metastasis of human ovarian cancer transplanted in nude mice]
Neoplasms
[Inhibitory effects of matrix metalloproteinase (MMP) inhibitor LY52 on expression of MMP-2 and MMP-9 and invasive ability of human ovarian carcinoma cell line SKOV3]
Neoplasms
[Interference of HIF-1alpha by RNA reduces the expression of matrix metalloproteinase-2 in human cervical carcinoma HeLa cells]
Neoplasms
[Interstitial collagenase, gelatinases A and B and their endogenous inhibitors in squamous cell cervical carcinomas].
Neoplasms
[Lentivirus media miR-1246 knockdown inhibits tumor growth and promotes apoptosis of SiHa cells].
Neoplasms
[Matricryptins derived from non fibrillar collagens, MMP-2 and SPARC are involved in the control of angiogenesis]
Neoplasms
[Matrix metalloproteinase 2 and 9 as the factor of head and neck tumor metastasis]
Neoplasms
[Matrix metalloproteinase-2 concentrations in squamous cell carcinoma of the head and neck and its clinical significance]
Neoplasms
[Matrix metalloproteinase-2 expression and its correlation with mesorectal metastasis in middle and lower rectal cancer]
Neoplasms
[Matrix metalloproteinases 2 and 9, their endogenous regulators, and angiotensin-converting enzyme in cervical squamous cell carcinoma].
Neoplasms
[Matrix metalloproteinases and their endogenous regulators in squamous cervical carcinoma (review of the own data)].
Neoplasms
[Matrix metalloproteinases and their tissue inhibitors in malignancies of the female genital tract]
Neoplasms
[Mechanism of EGFR Over-expression and Mutations Leading to ?Biological Characteristics Changes of Human Lung Adenocarcinoma Cells ?through CXCR4/CXCL12 Signaling Pathway].
Neoplasms
[Metastatic ability and type IV collagenase expression of oncogene-transformed human bronchial epithelial cells]
Neoplasms
[mRNA expression analysis of metastatic markers in clear-cell renal cell carcinoma]
Neoplasms
[New direct assay method of type IV collagenase in tissue homogenate and biochemical role of collagenase against type I, and IV collagens to the invasion of the stomach and lung cancer]
Neoplasms
[Over-expression of Hypoxia-inducible factor 1alpha increases invasive potency of LNCaP cells in vitro]
Neoplasms
[Preparation, identification and application of monoclonal antibody against matrix metalloproteinases-2].
Neoplasms
[Promotion of MAG-1 on Metastasis of Lung Cancer Cells in vitro and Its Expression in Lung Cancer Tissue of 24 Cases.]
Neoplasms
[Proteases by reactive stromal cells in cancer: an attractive therapeutic target]
Neoplasms
[Relationship between biochemical parameters of cerebrospinal fluid and the course of multiple sclerosis].
Neoplasms
[Relationship between serum matrix metalloproteinase-2 and metastasis and recurrence following radical hepatic resection in hepatocellular carcinoma]
Neoplasms
[Relationship of the disturbed balance between matrix metalloproteinases and their tissue inhibitors and the invasion of malignant salivary gland tumours]
Neoplasms
[RNAi-mediated Silencing of CXCR4 Inhibits the Adhesion, Invasion and Tumorigenicity of Acute Monocytic Leukemic Cell Line SHI-1].
Neoplasms
[Role of matrix metalloproteinase-2 and components of the extracellular matrix--collagen type IV and laminin expression in detection of the invasive potential of pancreatic tumors]
Neoplasms
[Role of matrix metalloproteinases-9, 2 and their inhibitor-TIMP-1, 2 in invasive pituitary adenomas biological behavior]
Neoplasms
[Role of organ specific fibroblasts in metastasis of human renal cell carcinoma: regulation of type IV collagenase production from human renal cell carcinoma by organ specific fibroblasts]
Neoplasms
[Role of siRNA mediated matrix metalloproteinase-2 gene silencing in the inhibition of invasion and growth of laryngeal cancer cells]
Neoplasms
[Role of type IV collagenase in tumor cell invasion and effect of laminin on invasive potential in bile duct carcinoma]
Neoplasms
[Role of type IV collagene and type IV collagenase in the invasion and metastasis of salivary adenoid cystic carcinoma]
Neoplasms
[Role of vascular endothelial growth factor overexpression in ovarian tumor invasion and mechanism]
Neoplasms
[Roles of serine proteases and matrix metalloproteinases in tumor invasion and angiogenesis]
Neoplasms
[Serum level of MMP-2 in early breast cancer and its correlation with circulating tumor cells].
Neoplasms
[Significance of activated matrix metalloproteinase 2 (MMP2) in progression of bladder transitional cell carcinoma]
Neoplasms
[Study on effect of arsenic trioxide on adhesion and invasion of human hepatocarcinoma cells in vitro]
Neoplasms
[Study on expression of matrix metalloproteinases and their inhibitors in parotid gland tumors]
Neoplasms
[Study on post-translational processing and active forms of the novel metastasis-associated protein SNC19]
Neoplasms
[The correlation between neck lymphy node metastasis and matrixmetalloproteinase-2 expression at the invasive tumor front of oral squamous cell carcinomas]
Neoplasms
[The correlation between polymorphisms of matrix metalloproteinase-2 and -9 genes and colorectal cancer of Chinese patients]
Neoplasms
[The effects of MMPs and TIMPs on the metastasis of oral squamous cell carcinoma to neck lymph nodes]
Neoplasms
[The expression and its clinical significance of MMP-2 and MMP-9 in non-small cell lung cancer.]
Neoplasms
[The expression of matrix metalloproteinase-2 and -9 in cervical cancer and a study of their relationship]
Neoplasms
[The expression of matrix metalloproteinases and their tissue inhibitors in pleomorphic adenoma]
Neoplasms
[The expression of matrix metalloproteinases and tissue inhibitor of metalloproteinases in transplanted tumor of salivary adenoid cystic carcinoma cell lines]
Neoplasms
[The influence of c-Myc, Ki-67, MMP-2 and VEGF expression on the prognosis of hepatocellular carcinoma patients with tumor resection.]
Neoplasms
[The matrix metalloproteinase in oral and oropharyngeol cancer - literature review].
Neoplasms
[The mechanism and pulmonary-protective effects of endothelin-1 receptor antagonist in chronic obstructive pulmonary diseases rat model].
Neoplasms
[The mechanisms of microenvironments influence on vasculogenic mimicry between introcular and subcutaneous melanoma]
Neoplasms
[The relationships between angiogenesis and matrix metalloproteinase-2, -9 in mice tumor intervened by feiyanning recipe's components].
Neoplasms
[The Role and Mechanism of CXCR4 and Its Ligand SDF-1 in the Development of Cervical Cancer Metastasis.]
Neoplasms
[The serum concentration of metalloproteinase 9 and 2 in non-small cell lung cancer patients]
Neoplasms
[The utility of metalloproteinases (MMPs) and their inhibitors (TIMPs) in diagnostics of gynecological malignancies].
Neoplasms
[Type IV collagenase activities in human colorectal cancers and its role in cancer invasion and metastasis]
Neoplasms
[VALUE OF METALPROTEINASES OF BLOOD IN PATHOGENESIS OF EPITELIAL SKIN TUMORS AND THE POSSIBILITY OF THEIR SURGICAL CORRECTION].
Neoplasms
[Y-27632 reduces the MMP2 and MMP9 expression in endothelial cell via inhibition of ROCK signal pathway].
Neoplasms
[Zymography--method for quantitation of activity on gelatinase A (pro-MMP-2, 72 kDa) and gelatinase B (pro-MMP-9, 92 kDa) in serum of patients with breast cancer]
Neoplasms, Germ Cell and Embryonal
Imbalance of MMP-2 and MMP-9 expression versus TIMP-1 and TIMP-2 reflects increased invasiveness of human testicular germ cell tumours.
Neoplasms, Germ Cell and Embryonal
[Correlation between expression of metastasis-related genes and lymph node metastasis in testicular cancer]
Neoplasms, Glandular and Epithelial
Transcriptional Factors for Epithelial-Mesenchymal Transition Are Associated with Mesenchymal Differentiation in Gliosarcoma.
Neoplasms, Neuroepithelial
Activated leukocyte cell adhesion molecule is expressed in neuroepithelial neoplasms and decreases with tumor malignancy, matrix metalloproteinase 2 expression, and absence of IDH1R132H mutation.
Neoplasms, Squamous Cell
Differential expression of matrilysin-1 (MMP-7), 92 kD gelatinase (MMP-9), and metalloelastase (MMP-12) in oral verrucous and squamous cell cancer.
Neoplastic Cells, Circulating
Circulating tumor cells and serum levels of MMP-2, MMP-9 and VEGF as markers of the metastatic process in patients with high risk of metastatic progression.
Neoplastic Cells, Circulating
EVALUATING MMP-2 AND TGFß-RI EXPRESSION IN CIRCULATING TUMOR CELLS OF PANCREATIC CANCER PATIENTS AND THEIR CORRELATION WITH CLINICAL EVOLUTION.
Neoplastic Cells, Circulating
[Serum level of MMP-2 in early breast cancer and its correlation with circulating tumor cells].
Nephritis
Altered expression of matrix-related molecules in the development of chronic Thy1.1 nephritis.
Nephritis
Differential glomerular immunoexpression of matrix metalloproteinases MMP-2 and MMP-9 in idiopathic IgA nephropathy and Schoenlein-Henoch nephritis.
Nephritis
Expression of MMP-9 in mesangial cells and its changes in anti-GBM glomerulonephritis in WKY rats.
Nephritis
Extracellular matrix deposition and cell proliferation in a model of chronic glomerulonephritis in the rat.
Nephritis
Gene expression of metalloproteinases and their inhibitor in renal tissue of New Zealand black/white F1 mice.
Nephritis
Neutrophil gelatinase associated lipocalin is instrumental in the pathogenesis of antibody-mediated nephritis.
Nephritis, Hereditary
Gelatinase B (MMP-9) is not essential in the normal kidney and does not influence progression of renal disease in a mouse model of Alport syndrome.
Nephritis, Hereditary
Increased expression of MMP-2, MMP-9 (type IV collagenases/gelatinases), and MT1-MMP in canine X-linked Alport syndrome (XLAS).
Nephrosis
Effect of a specific endothelin receptor A antagonist and an angiotensin-converting enzyme inhibitor on glomerular mRNA levels for extracellular matrix components, metalloproteinases (MMP) and a tissue inhibitor of MMP in aminonucleoside nephrosis.
Nephrosis, Lipoid
Specific changes in plasma concentrations of matrix metalloproteinase-2 and -9, TIMP-1 and TGF-beta1 in patients with distinct types of primary glomerulonephritis.
Nephrotic Syndrome
Association of neutrophil gelatinase associated lipocalin and cystatin-C with kidney function in children with nephrotic syndrome.
Nephrotic Syndrome
Distinct metalloproteinase excretion patterns in focal segmental glomerulosclerosis.
Nephrotic Syndrome
Specific changes in plasma concentrations of matrix metalloproteinase-2 and -9, TIMP-1 and TGF-beta1 in patients with distinct types of primary glomerulonephritis.
Nephrotic Syndrome
Urinary levels of matrix metalloproteinases and their tissue inhibitors in nephrotic children.
Nephrotic Syndrome
Urine Neutrophil Gelatinase Associated Lipocalin to Creatinine Ratio: A Novel Index for Steroid Response in Idiopathic Nephrotic Syndrome.
Nervous System Diseases
Gelatinase in the cerebrospinal fluid of patients with multiple sclerosis and other inflammatory neurological disorders.
Nervous System Diseases
Vascular cell adhesion molecule-1-mediated matrix metalloproteinase-2 induction in peripheral blood T cells is up-regulated in patients with HTLV-I-associated myelopathy.
Neuralgia
Antihyperalgesic and Anti-inflammatory Effects of Atorvastatin in Chronic Constriction Injury-Induced Neuropathic Pain in Rats.
Neuralgia
Biomarker Analysis of Orally Dosed, Dual Active, Matrix Metalloproteinase (MMP)-2 and MMP-9 Inhibitor, AQU-118, in the Spinal Nerve Ligation (SNL) Rat Model of Neuropathic Pain.
Neuralgia
Combination of autophagy and NFE2L2/NRF2 activation as a treatment approach for neuropathic pain.
Neuralgia
Distinct roles of matrix metalloproteases in the early- and late-phase development of neuropathic pain.
Neuralgia
DNMT3b SUMOylation Mediated MMP-2 Upregulation Contribute to Paclitaxel Induced Neuropathic Pain.
Neuralgia
Effect of a Novel, Orally Active Matrix Metalloproteinase-2 and -9 Inhibitor in Spinal and Trigeminal Rat Models of Neuropathic Pain.
Neuralgia
Folic Acid Modulates Matrix Metalloproteinase-2 Expression, Alleviates Neuropathic Pain, and Improves Functional Recovery in Spinal Cord-Injured Rats.
Neuralgia
Intrathecal CGS-26303 Pretreatment Attenuates Spinal Nerve Ligation-Induced Neuropathic Pain in the Spinal Cord.
Neuralgia
N-acetyl-cysteine attenuates neuropathic pain by suppressing matrix metalloproteinases.
Neuralgia
Paeoniflorin attenuates postoperative pain by suppressing Matrix Metalloproteinase-9/2 in mice.
Neuralgia
Pretreatment with resveratrol ameliorate trigeminal neuralgia by suppressing matrix metalloproteinase-9/2 in trigeminal ganglion.
Neuralgia
Procyanidins attenuate neuropathic pain by suppressing matrix metalloproteinase-9/2.
Neuralgia
Role of Matrix Metalloproteinases and Therapeutic Benefits of Their Inhibition in Spinal Cord Injury.
Neurilemmoma
Differences in proliferation and invasion by normal, transformed and NF1 Schwann cell cultures are influenced by matrix metalloproteinase expression.
Neurilemmoma
Nuclear localization of catalytically active MMP-2 in endothelial cells and neurons.
Neurilemmoma
Tumor invasion-inhibiting factor 2: primary structure and inhibitory effect on invasion in vitro and pulmonary metastasis of tumor cells.
Neurilemmoma
Uridine 5'-triphosphate promotes in vitro Schwannoma cell migration through matrix metalloproteinase-2 activation.
Neuritis
Matrix metalloproteinases MMP-9 and MMP-7 are expressed in experimental autoimmune neuritis and the Guillain-Barré syndrome.
Neuroblastoma
Angiogenesis extent and expression of matrix metalloproteinase-2 and -9 correlate with progression in human neuroblastoma.
Neuroblastoma
Constitutively active lysophosphatidic acid receptor-1 enhances the induction of matrix metalloproteinase-2.
Neuroblastoma
Determination of imbalance between MMP-2 and TIMP-2 in human neuroblastoma by reverse-transcription polymerase chain reaction and its correlation with tumor progression.
Neuroblastoma
Environmental endocrine disruptors promote invasion and metastasis of SK-N-SH human neuroblastoma cells.
Neuroblastoma
Estrogen activates matrix metalloproteinases-2 and -9 to increase beta amyloid degradation.
Neuroblastoma
Hepatocyte growth factor/c-Met signaling promotes the progression of experimental human neuroblastomas.
Neuroblastoma
Immunohistochemical expression of MMP-2, MMP-9, and TIMP-2 in neuroblastoma: association with tumor progression and clinical outcome.
Neuroblastoma
Insights on ornithine decarboxylase silencing as a potential strategy for targeting retinoblastoma.
Neuroblastoma
KLF4 overexpression and apigenin treatment down regulated anti-apoptotic Bcl-2 proteins and matrix metalloproteinases to control growth of human malignant neuroblastoma SK-N-DZ and IMR-32 cells.
Neuroblastoma
Knockdown of N-Acetylglucosaminyltransferase-II Reduces Matrix Metalloproteinase 2 Activity and Suppresses Tumorigenicity in Neuroblastoma Cell Line.
Neuroblastoma
Matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 expression in paediatric tumour cells. Effects of tumour cell proliferation modulators on gelatinolytic activity.
Neuroblastoma
Matrix Metalloproteinase-9 and Cell Division in Neuroblastoma Cells and Bone Marrow Macrophages.
Neuroblastoma
Membrane-type matrix metalloproteinase-1 expression and activation of gelatinase A as prognostic markers in advanced pediatric neuroblastoma.
Neuroblastoma
miR-338-3p inhibits cell growth, invasion, and EMT process in neuroblastoma through targeting MMP-2.
Neuroblastoma
Mulberry leaf extract inhibits invasive potential and downregulates hypoxia-inducible factor-1? (HIF-1?) in SK-N-BE2C neuroblastoma cells.
Neuroblastoma
N-Myc and Bcl-2 coexpression induces MMP-2 secretion and activation in human neuroblastoma cells.
Neuroblastoma
N-Myc down regulation induced differentiation, early cell cycle exit, and apoptosis in human malignant neuroblastoma cells having wild type or mutant p53.
Neuroblastoma
Platelet activating factor inhibits the expression of matrix metalloproteinases and affects invasiveness and differentiation in a system of human neuroblastoma clones.
Neuroblastoma
Role of estrogen receptor alpha in MEHP-induced proliferation and invasion of SH-SY5Y cells.
Neuroblastoma
S100A4 antisense oligodeoxynucleotide suppresses invasive potential of neuroblastoma cells.
Neuroblastoma
Silencing of Y-box binding protein-1 by RNA interference inhibits proliferation, invasion, and metastasis, and enhances sensitivity to cisplatin through NF-?B signaling pathway in human neuroblastoma SH-SY5Y cells.
Neuroblastoma
Stanniocalcin 2 promotes invasion and is associated with metastatic stages in neuroblastoma.
Neuroblastoma
Stromal matrix metalloproteinase-9 regulates the vascular architecture in neuroblastoma by promoting pericyte recruitment.
Neuroblastoma
Structure-function studies on inhibitory activity of Bungarus multicinctus protease inhibitor-like protein on matrix metalloprotease-2, and invasion and migration of human neuroblastoma SK-N-SH cells.
Neuroblastoma
The neuroprotective role of tissue inhibitor of metalloproteinase-2 in MPP+- or 6-OHDA-treated SK-N-BE(2)C and SH-SY5Y human neuroblastoma cells.
Neuroblastoma
The novel anti-neuroblastoma agent PF403, inhibits proliferation and invasion in vitro and in brain xenografts.
Neuroblastoma
Therapeutic Efficacy of Silibinin on Human Neuroblastoma Cells: Akt and NF-?B Expressions May Play an Important Role in Silibinin-Induced Response.
Neuroblastoma
Thioredoxin alters the matrix metalloproteinase/tissue inhibitors of metalloproteinase balance and stimulates human SK-N-SH neuroblastoma cell invasion.
Neuroblastoma
Thymoquinone inhibits the migration of mouse neuroblastoma (Neuro-2a) cells by down-regulating MMP-2 and MMP-9.
Neuroblastoma
TLX activates MMP-2, promotes self-renewal of tumor spheres in neuroblastoma and correlates with poor patient survival.
Neuroblastoma
[Correlation between expression of MMP-2, MMP-9, TIMP-2, TIMP-1 and metastasis of neuroblastoma]
Neurocysticercosis
Association of MMP-2 and MMP-9 with clinical outcome of neurocysticercosis.
Neurodegenerative Diseases
Examination of Gelatinase Isoforms in Rodent Models of Acute Neurodegenerative Diseases Using Two-Dimensional Zymography.
Neuroectodermal Tumors
Matrix metalloproteinase expression in childhood medulloblastomas/primitive neuroectodermal tumors.
Neuroectodermal Tumors
Significant differences in the matrix metalloproteinase expression profiles of spontaneous medulloblastomas/primitive neuroectodermal tumors as compared with their xenografted, established tumor cell line derived counterparts.
Neurofibroma
Differences in proliferation and invasion by normal, transformed and NF1 Schwann cell cultures are influenced by matrix metalloproteinase expression.
Neuroinflammatory Diseases
Delayed administration of a matrix metalloproteinase inhibitor limits progressive brain injury after hypoxia-ischemia in the neonatal rat.
Neuroinflammatory Diseases
Examination of Gelatinase Isoforms in Rodent Models of Acute Neurodegenerative Diseases Using Two-Dimensional Zymography.
Neuroinflammatory Diseases
Gelatinase B is present in the cerebrospinal fluid during experimental autoimmune encephalomyelitis and cleaves myelin basic protein.
Neuroinflammatory Diseases
Natural Marine and Terrestrial Compounds as Modulators of Matrix Metalloproteinases-2 (MMP-2) and MMP-9 in Alzheimer's Disease.
Neuroinflammatory Diseases
New in vivo compatible matrix metalloproteinase (MMP)-2 and MMP-9 inhibitors.
Neuroinflammatory Diseases
On the structure and functions of gelatinase B/matrix metalloproteinase-9 in neuroinflammation.
Neuroinflammatory Diseases
Paeoniflorin attenuates postoperative pain by suppressing Matrix Metalloproteinase-9/2 in mice.
Neuroinflammatory Diseases
Potential relevance of cerebrospinal fluid and serum levels and intrathecal synthesis of active matrix metalloproteinase-2 (MMP-2) as markers of disease remission in patients with multiple sclerosis.
Neuroinflammatory Diseases
Stromelysin-1 and gelatinase A are upregulated before TNF-alpha in LPS-stimulated neuroinflammation.
Neuroinflammatory Diseases
The gelatinases, MMP-2 and MMP-9, as fine tuners of neuroinflammatory processes.
Neurologic Manifestations
Serum values of metalloproteinase-2 and metalloproteinase-9 as related to unstable plaque and inflammatory cells in patients with greater than 70% carotid artery stenosis.
Neuroma, Acoustic
Angiogenesis in vestibular schwannomas: expression of extracellular matrix factors MMP-2, MMP-9, and TIMP-1.
Neuroma, Acoustic
Association of cavernous malformation within vestibular schwannoma: immunohistochemical analysis of matrix metalloproteinase-2 and -9.
Neuroma, Acoustic
Cystic vestibular schwannomas: a possible role of matrix metalloproteinase-2 in cyst development and unfavorable surgical outcome.
Neuromyelitis Optica
Increased cerebrospinal fluid metalloproteinase-2 and interleukin-6 are associated with albumin quotient in neuromyelitis optica: Their possible role on blood-brain barrier disruption.
Neurosyphilis
Expression of matrix metalloproteinases and their tissue inhibitors in the serum and cerebrospinal fluid of patients with HIV-1 infection and syphilis or neurosyphilis.
Neutropenia
Matrix metalloproteinase-2 polymorphisms and clinical outcome of Chinese patients with nonsmall cell lung cancer treated with first-line, platinum-based chemotherapy.
Nevus
Active and inactive forms of matrix metalloproteinases 2 and 9 in cutaneous melanoma.
Nevus
Coordinate expression of membrane type-matrix metalloproteinases-2 and 3 (MT2-MMP and MT3-MMP) and matrix metalloproteinase-2 (MMP-2) in primary and metastatic melanoma cells.
Nevus
Expression of matrix metalloproteinase (MMP)-2, MMP-9, and tissue inhibitor of MMP (TIMP)-1 in conjunctival melanomas and clinical implications.
Nevus
Immunohistochemical expression of vascular endothelial growth factor, matrix metalloproteinase 2, and matrix metalloproteinase 9 in cutaneous melanocytic lesions.
Nevus
Loss of dipeptidyl peptidase IV immunostaining discriminates malignant melanomas from deep penetrating nevi.
Nevus
MMP-2, TIMP-2 and MT1-MMP are differentially expressed in lesional skin of melanocytic nevi and their expression is modulated by UVB-light.
Nevus
PKC and PKA phosphorylation affect the subcellular localization of claudin-1 in melanoma cells.
Nevus
The 'Abtropfung phenomenon' revisited: Dermal nevus cells from congenital nevi cannot activate matrix metalloproteinase 2 (MMP-2).
Nevus, Pigmented
Active and inactive forms of matrix metalloproteinases 2 and 9 in cutaneous melanoma.
Nevus, Pigmented
Immunohistochemical expression of matrix metalloproteinase-2 and -9 in melanocytic nevi is altered by ultraviolet B.
Nevus, Pigmented
Immunohistochemical expression of vascular endothelial growth factor, matrix metalloproteinase 2, and matrix metalloproteinase 9 in cutaneous melanocytic lesions.
Nevus, Pigmented
MMP-2, TIMP-2 and MT1-MMP are differentially expressed in lesional skin of melanocytic nevi and their expression is modulated by UVB-light.
Non-alcoholic Fatty Liver Disease
Animal Models of Steatosis (NAFLD) and Steatohepatitis (NASH) Exhibit Hepatic Lobe-Specific Gelatinases Activity and Oxidative Stress.
Non-alcoholic Fatty Liver Disease
Evaluation of the Effect Derived from Silybin with Vitamin D and Vitamin E Administration on Clinical, Metabolic, Endothelial Dysfunction, Oxidative Stress Parameters, and Serological Worsening Markers in Nonalcoholic Fatty Liver Disease Patients.
Non-alcoholic Fatty Liver Disease
Expression of Matrix Metalloproteinases and Their Tissue Inhibitors in Peripheral Blood Leukocytes and Plasma of Children with Nonalcoholic Fatty Liver Disease.
Non-alcoholic Fatty Liver Disease
Interactions of central obesity with rs3918242 on risk of non-alcoholic fat liver disease: a preliminary case-control study.
Non-alcoholic Fatty Liver Disease
Pioglitazone suppresses inflammation and fibrosis in nonalcoholic fatty liver disease by down-regulating PDGF and TIMP-2: Evidence from in vitro study.
Non-alcoholic Fatty Liver Disease
Serum biomarkers of fibrosis and extracellular matrix remodeling in patients with nonalcoholic fatty liver disease: association with liver histology.
Non-alcoholic Fatty Liver Disease
[Study on the interaction between matrix metalloproteinases gene polymorphism and central obesity in nonalcoholic fatty liver disease].
Obesity
A functional role of gelatinase A in the development of nutritionally induced obesity in mice.
Obesity
Acute eccentric resistance exercise decreases matrix metalloproteinase activity in obese elderly women.
Obesity
Cleavage of the leptin receptor by matrix metalloproteinase-2 promotes leptin resistance and obesity in mice.
Obesity
Decreased Collagen Type I is Associated with Increased Metalloproteinase-2 Activity and Protein Expression of Leptin in the Myocardium of Obese Rats.
Obesity
Do different bariatric surgical procedures influence plasma levels of matrix metalloproteinase-2, -7, and -9 among patients with type 2 diabetes mellitus?
Obesity
Effect of metabolic syndrome risk factors and MMP-2 genetic variations on circulating MMP-2 levels in childhood obesity.
Obesity
Increase in MMP-2 activity in overweight and obese women is associated with menopausal status.
Obesity
Increased adipose tissue expression of lipocalin-2 in obesity is related to inflammation and matrix metalloproteinase-2 and metalloproteinase-9 activities in humans.
Obesity
Leptin-induced matrix metalloproteinase-2 secretion is suppressed by trans-10,cis-12 conjugated linoleic acid.
Obesity
Matrix Metallopeptidase 2 Gene Polymorphism is Associated with Obesity in Korean Population.
Obesity
Matrix Metalloproteinases and Their Role in Mechanisms Underlying Effects of Quercetin on Heart Function in Aged Zucker Diabetic Fatty Rats.
Obesity
MMP-2 and MMP-9 levels in plasma are altered and associated with mortality in COVID-19 patients.
Obesity
Nuclear factor-kappaB induction by visfatin in human vascular endothelial cells: its role in MMP-2/9 production and activation.
Obesity, Abdominal
Interactions of central obesity with rs3918242 on risk of non-alcoholic fat liver disease: a preliminary case-control study.
Obesity, Abdominal
[Study on the interaction between matrix metalloproteinases gene polymorphism and central obesity in nonalcoholic fatty liver disease].
Obstetric Labor Complications
The expression of matrix metalloproteinases in placental tissue depends on the severity of undifferentiated connective tissue dysplasia.
Obstetric Labor, Premature
Changes in matrix metalloproteinase (MMP)-2 and MMP-9 in the fetal amnion and chorion during gestation and at term and preterm labor.
Obstetric Labor, Premature
Collagenolytic enzymes (gelatinases) and their inhibitors in human amniochorionic membrane.
Obstetric Labor, Premature
Evidence of in vivo differential bioavailability of the active forms of matrix metalloproteinases 9 and 2 in parturition, spontaneous rupture of membranes, and intra-amniotic infection.
Obstetric Labor, Premature
Low maternal serum matrix metalloproteinase (MMP)-2 concentrations are associated with preterm labor and fetal inflammatory response.
Obstetric Labor, Premature
Matrix metalloproteinases in the cervical mucus plug in relation to gestational age, plug compartment, and preterm labor.
Obstetric Labor, Premature
Matrix metalloproteinases-2 and -9 and their endogenous tissue inhibitors in tissue remodeling after sealing of the fetal membranes in a sheep model of fetoscopic surgery.
Obstetric Labor, Premature
Matrix metalloproteinases-2, -3 and tissue inhibitors of metalloproteinases -1, -2 in placentas from preterm pregnancies and their association with one carbon metabolites.
Obstetric Labor, Premature
Programmed cell death (apoptosis) as a possible pathway to metalloproteinase activation and fetal membrane degradation in premature rupture of membranes.
Odontogenic Cysts
Discrimination of ameloblastomas from odontogenic keratocysts by cytokine levels and gelatinase species of the intracystic fluids.
Odontogenic Cysts
Interleukin-1alpha enhances type I collagen-induced activation of matrix metalloproteinase-2 in odontogenic keratocyst fibroblasts.
Odontogenic Cysts
Laminin-5 gamma 2 chain is colocalized with gelatinase-A (MMP-2) and collagenase-3 (MMP-13) in odontogenic keratocysts.
Odontogenic Tumors
Comparison of osteoclastogenesis and local invasiveness of ameloblastoma and keratocystic odontogenic tumor.
Odontogenic Tumors
Correlation between radiographic area and immunolocation of MMP-2 and MMP-9 in unilocular radiographic lesions.
Odontogenic Tumors
Immunoexpression of MMPs-1, -2, and -9 in ameloblastoma and odontogenic adenomatoid tumor.
Odontogenic Tumors
Presence of myofibroblasts and matrix metalloproteinase 2 in radicular cysts, dentigerous cysts, and keratocystic odontogenic tumors: a comparative immunohistochemical study.
Olfactory Nerve Injuries
Peak in matrix metaloproteinases-2 levels observed during recovery from olfactory nerve injury.
Oligodendroglioma
Correlations of polymorphisms in matrix metalloproteinase-1, -2, and -7 promoters to susceptibility to malignant gliomas.
Oligodendroglioma
Expression of MMP-2, MMP-7, MMP-9, MMP-10 and MMP-11 in human astrocytic and oligodendroglial gliomas.
Oligodendroglioma
Matrix metalloproteinase 2 (MMP-2) immunoreactive protein is associated with poor grade and survival in brain neoplasms.
Opportunistic Infections
Increased activity of matrix metalloproteinases in the cerebrospinal fluid of patients with HIV-associated neurological diseases.
Optic Neuritis
Association of MMP-2 (?1306 C/T) Gene Polymorphism with Predisposition to Optic Neuritis and Optic Neuritis Together with Multiple Sclerosis.
Optic Neuritis
MMP-2 -1575G/A polymorphism modifies the onset of optic neuritis as a first presenting symptom in MS?
Oral Submucous Fibrosis
Expression of matrix metalloproteinases (MMP-1, MMP-2 and MMP-9) and their inhibitors (TIMP-1 and TIMP-2) in oral submucous fibrosis.
Oral Submucous Fibrosis
Increased tissue inhibitor of metalloproteinase-1 expression and inhibition of gelatinase A activity in buccal mucosal fibroblasts by arecoline as possible mechanisms for oral submucous fibrosis.
Oral Submucous Fibrosis
Oral submucous fibrosis stimulates invasion and epithelial-mesenchymal transition in oral squamous cell carcinoma by activating MMP-2 and IGF-IR.
Oral Submucous Fibrosis
Role of functional polymorphism of matrix metalloproteinase-2 (-1306 C/T and -168 G/T) and MMP-9 (-1562 C/T) promoter in oral submucous fibrosis and head and neck squamous cell carcinoma in an Indian population.
Osteoarthritis
Association of (-1,607) 1G/2G polymorphism of matrix metalloproteinase-1 gene with knee osteoarthritis in the Turkish population (knee osteoarthritis and MMPs gene polymorphisms).
Osteoarthritis
Basic calcium phosphate crystals induce synthesis and secretion of 92 kDa gelatinase (gelatinase B/matrix metalloprotease 9) in human fibroblasts.
Osteoarthritis
Biomarkers for identifying the early phases of osteoarthritis secondary to medial patellar luxation in dogs.
Osteoarthritis
Cadherin-11 involves in synovitis and increases the migratory and invasive capacity of fibroblast-like synoviocytes of osteoarthritis.
Osteoarthritis
CD147 overexpression on synoviocytes in rheumatoid arthritis enhances matrix metalloproteinase production and invasiveness of synoviocytes.
Osteoarthritis
Clinical Correlation with the PA/Plasmin System in Septic Arthritis of the Knee.
Osteoarthritis
Differential regulation of gelatinases by transforming growth factor beta-1 in normal equine chondrocytes.
Osteoarthritis
Effects of treatment with polysulfated glycosaminoglycan on serum cartilage oligomeric matrix protein and C-reactive protein concentrations, serum matrix metalloproteinase-2 and -9 activities, and lameness in dogs with osteoarthritis.
Osteoarthritis
Elevation of activated protein C in synovial joints in rheumatoid arthritis and its correlation with matrix metalloproteinase 2.
Osteoarthritis
Evaluation of serum MMP-2 and MMP-3, synovial fluid IL-8, MCP-1, and KC concentrations as biomarkers of stifle osteoarthritis associated with naturally occurring cranial cruciate ligament rupture in dogs.
Osteoarthritis
Immunolocalisation studies on six matrix metalloproteinases and their inhibitors, TIMP-1 and TIMP-2, in synovia from patients with osteo- and rheumatoid arthritis.
Osteoarthritis
Matrix metalloproteinase (MMP)-2, MMP-9 and MMP-13 are activated by Activated Protein C (APC) in human osteoarthritic cartilage chondrocytes.
Osteoarthritis
Matrix metalloproteinase and tissue inhibitor of metalloproteinase in serum and synovial fluid of osteoarthritic dogs.
Osteoarthritis
Matrix metalloproteinase-2 in synovial lavage fluid of patients with disorders of the temporomandibular joint.
Osteoarthritis
Neutrophil gelatinase levels in plasma and synovial fluid of patients with rheumatic diseases.
Osteoarthritis
Potent collagenase inhibitors prevent interleukin-1-induced cartilage degradation in vitro.
Osteoarthritis
Recent findings on the role of gelatinases (matrix metalloproteinase-2 and -9) in osteoarthritis.
Osteoarthritis
Regulation of 2-deoxy-D-glucose transport, lactate metabolism, and MMP-2 secretion by the hypoxia mimetic cobalt chloride in articular chondrocytes.
Osteoarthritis
Regulation of gelatinases expression by cytokines, endotoxin, and pharmacological agents in the human osteoarthritic knee.
Osteoarthritis
Resistance training decreases matrix metalloproteinase-2 activity in quadriceps tendon in a rat model of osteoarthritis.
Osteoarthritis
Serum TGF-beta2 and TGF-beta3 are increased and positively correlated to pain, functionality, and radiographic staging in osteoarthritis.
Osteoarthritis
Structure of the catalytic domain of human fibroblast collagenase complexed with an inhibitor.
Osteoarthritis
Sulfated glucosamine inhibits MMP-2 and MMP-9 expressions in human fibrosarcoma cells.
Osteoarthritis
Suppressive effect of secretory phospholipase A2 inhibitory peptide on interleukin-1beta-induced matrix metalloproteinase production in rheumatoid synovial fibroblasts, and its antiarthritic activity in hTNFtg mice.
Osteoarthritis
Sustained and distinctive patterns of gene activation in synovial fibroblasts and whole synovial tissue obtained from inflammatory synovitis.
Osteoarthritis
Synovial matrix metalloproteinase-2 in different stages of sheep temporomandibular joint osteoarthrosis.
Osteoarthritis
Upregulation of urokinase-type plasminogen activator and inhibitor and gelatinase expression via 3 mitogen-activated protein kinases and PI3K pathways during the early development of osteoarthritis.
Osteoarthritis
Urokinase-type plasminogen activator, receptor, and inhibitor correlating with gelatinase-B (MMP-9) contribute to inflammation in gouty arthritis of the knee.
Osteoarthritis, Knee
Association of (-1,607) 1G/2G polymorphism of matrix metalloproteinase-1 gene with knee osteoarthritis in the Turkish population (knee osteoarthritis and MMPs gene polymorphisms).
Osteoarthritis, Knee
Effect of low intensity pulsed ultrasound on expression of TIMP-2 in serum and expression of mmp-13 in articular cartilage of rabbits with knee osteoarthritis.
Osteoarthritis, Knee
Preventive administration of juanbi capsules for knee osteoarthritis: effects on serum MMP-2 and MMP-9 levels and cartilage repair.
Osteoarthritis, Knee
TIMP-2 SNPs rs7342880 and rs4789936 are linked to risk of knee osteoarthritis in the Chinese Han Population.
Osteochondrodysplasias
Expression of Genes Encoding Extracellular Matrix Macromolecules and Metalloproteinases in Avian Tibial Dyschondroplasia.
Osteolysis
A crucial role for matrix metalloproteinase 2 in osteocytic canalicular formation and bone metabolism.
Osteolysis
Absence of MMP2 mutation in idiopathic multicentric osteolysis with nephropathy.
Osteolysis
Characterization of Normal Murine Carpal Bone Development Prompts Re-Evaluation of Pathologic Osteolysis as the Cause of Human Carpal-Tarsal Osteolysis Disorders.
Osteolysis
Clinical and radiographic findings in two brothers affected with a novel mutation in matrix metalloproteinase 2 gene.
Osteolysis
Genetic susceptibility to aseptic loosening following total hip arthroplasty: a systematic review.
Osteolysis
Histologic and biochemical differences between osteolytic and nonosteolytic membranes around femoral components of an uncemented total hip arthroplasty.
Osteolysis
Immunolocalization of MMP 2, 9 and 13 in prednisolone induced osteoporosis in mice.
Osteolysis
Inhibition of human prostate cancer growth, osteolysis and angiogenesis in a bone metastasis model by a novel mechanism-based selective gelatinase inhibitor.
Osteolysis
Integrin ?v?6 Promotes an Osteolytic Program in Cancer Cells by Upregulating MMP2.
Osteolysis
p38 signaling in titanium particle-induced MMP-2 secretion and activation in differentiating MC3T3-E1 cells.
Osteolysis
Polyethylene wear particles do not induce inflammation or gelatinase (MMP-2 and MMP-9) activity in fibrous tissue interfaces of loosening total hip arthroplasties.
Osteolysis
Possible role of matrix metalloproteinase in osteolytic intracranial meningiomas.
Osteolysis, Essential
Absence of MMP2 mutation in idiopathic multicentric osteolysis with nephropathy.
Osteoporosis
Absence of MMP2 mutation in idiopathic multicentric osteolysis with nephropathy.
Osteoporosis
Dynamic expression of matrix metalloproteinases 2, 9 and 13 in ovariectomy-induced osteoporosis rats.
Osteoporosis
Immunolocalization of MMP 2, 9 and 13 in prednisolone induced osteoporosis in mice.
Osteoporosis
Relationship of circulating MMP-2, MMP-1, and TIMP-1 levels with bone biochemical markers and bone mineral density in postmenopausal Chinese women.
Osteoporosis
Relationships between serum osteoprotegerin, matrix metalloproteinase-2 levels and bone metabolism in postmenopausal women.
Osteoporosis
[Relationships between circulating matrix metalloproteinase-1, -2 and metalloproteinase-1 levels and bone biochemical markers and bone mineral density in Chinese postmenopausal women]
Osteoporosis, Postmenopausal
Effects of 17beta-estradiol and progesterone on the expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in rat osteoblasts.
Osteoporosis, Postmenopausal
Relationships between serum osteoprotegerin, matrix metalloproteinase-2 levels and bone metabolism in postmenopausal women.
Osteoporosis, Postmenopausal
[Age-related changes serum levels of MMP-1 and MMP-2 in women: their relationship with bone biochemical markers and bone mineral density]
Osteoporosis, Postmenopausal
[Effects of Migu tablet on bone mineral density, serum matrix metalloproteinase-2 level and bone metabolic markers in postmenopausal osteoporosis]
Osteoporosis, Postmenopausal
[Relationships between circulating matrix metalloproteinase-1, -2 and metalloproteinase-1 levels and bone biochemical markers and bone mineral density in Chinese postmenopausal women]
Osteosarcoma
Alendronate regulates cell invasion and MMP-2 secretion in human osteosarcoma cell lines.
Osteosarcoma
Antitumor effect of nutrient synergy on human osteosarcoma cells U-2OS, MNNG-HOS and Ewing's sarcoma SK-ES.1.
Osteosarcoma
Astrocyte elevated gene-1 (AEG-1) promotes osteosarcoma cell invasion through the JNK/c-Jun/MMP-2 pathway.
Osteosarcoma
B7-H3 is Overexpressed in Patients Suffering Osteosarcoma and Associated with Tumor Aggressiveness and Metastasis.
Osteosarcoma
Bufalin-inhibited migration and invasion in human osteosarcoma U-2 OS cells is carried out by suppression of the matrix metalloproteinase-2, ERK, and JNK signaling pathways.
Osteosarcoma
Colchicine induces membrane-associated activation of matrix metalloproteinase-2 in osteosarcoma cells in an S100A4-independent manner.
Osteosarcoma
Collagen I regulates matrix metalloproteinase-2 activation in osteosarcoma cells independent of S100A4.
Osteosarcoma
Compounds isolated from Ageratum houstonianum inhibit the activity of matrix metalloproteinases (MMP-2 and MMP-9): An oncoinformatics study.
Osteosarcoma
Cyr61 silencing reduces vascularization and dissemination of osteosarcoma tumors.
Osteosarcoma
Delivery of inhibitor of growth 4 (ING4) gene significantly inhibits proliferation and invasion and promotes apoptosis of human osteosarcoma cells.
Osteosarcoma
Depletion of alphaV integrins from osteosarcoma cells by intracellular antibody expression induces bone differentiation marker genes and suppresses gelatinase (MMP-2) synthesis.
Osteosarcoma
Distribution and activity levels of matrix metalloproteinase 2 and 9 in canine and feline osteosarcoma.
Osteosarcoma
Disulfiram suppresses invasive ability of osteosarcoma cells via the inhibition of MMP-2 and MMP-9 expression.
Osteosarcoma
Downregulation of matrix metalloproteinase-9 mRNA by valproic acid plays a role in inhibiting the shedding of MHC class I-related molecules A and B on the surface of human osteosarcoma cells.
Osteosarcoma
EFEMP1 promotes the migration and invasion of osteosarcoma via MMP-2 with induction by AEG-1 via NF-?B signaling pathway.
Osteosarcoma
Effect of human osteopontin on proliferation, transmigration and expression of MMP-2 and MMP-9 in osteosarcoma cells.
Osteosarcoma
Endothelin-1 (ET-1) promotes MMP-2 and MMP-9 induction involving the transcription factor NF-kappaB in human osteosarcoma.
Osteosarcoma
Examination of the signal transduction pathways leading to activation of gelatinolytic activity by interleukin-1alpha and Porphyromonas gingivalis in human osteosarcoma cells.
Osteosarcoma
Exogenously added GPI-anchored tissue inhibitor of matrix metalloproteinase-1 (TIMP-1) displays enhanced and novel biological activities.
Osteosarcoma
Expression of CXCR4 and MMP-2 is associated with poor prognosis in patients with osteosarcoma.
Osteosarcoma
Expression of metalloproteinases and tissue inhibitors of metalloproteinases in human osteoblast-like cells: differentiation is associated with repression of metalloproteinase biosynthesis.
Osteosarcoma
Genetic polymorphisms in MMP 2, 3 and 9 genes and the susceptibility of osteosarcoma in a Chinese Han population.
Osteosarcoma
Human hepatoma cells produce an 85 kDa gelatinase regulated by phorbol 12-myristate 13-acetate.
Osteosarcoma
In vitro modulation of MMP-2 and MMP-9 in pediatric human sarcoma cell lines by cytokines, inducers and inhibitors.
Osteosarcoma
Increased expression of membrane-type matrix metalloproteinase-1 is correlated with poor prognosis in patients with osteosarcoma.
Osteosarcoma
Inhibition of human osteosarcoma cell migration and invasion by a gene silencer, pyrrole-imidazole polyamide, targeted at the human MMP9 NF-?B binding site.
Osteosarcoma
Inhibitory effect of a mixture containing ascorbic acid, lysine, proline and green tea extract on critical parameters in angiogenesis.
Osteosarcoma
Involvement of MMP-2 in adriamycin resistance dependent on ERK1/2 signal pathway in human osteosarcoma MG-63 cells.
Osteosarcoma
Irisin reverses the IL-6 induced epithelial-mesenchymal transition in osteosarcoma cell migration and invasion through the STAT3/Snail signaling pathway.
Osteosarcoma
Ketoprofen in topical formulation decreases the matrix metalloproteinase-2 expression and pulmonary metastatic incidence in nude mice with osteosarcoma.
Osteosarcoma
LINC00968 functions as an oncogene in osteosarcoma by activating the PI3K/AKT/mTOR signaling.
Osteosarcoma
Long non-coding RNA lncTCF7 predicts poor prognosis and promotes tumor metastasis in osteosarcoma.
Osteosarcoma
Matrix metalloproteinase 2 expression and survival of patients with osteosarcoma: a meta-analysis.
Osteosarcoma
Modulation of u-PA, MMPs and their inhibitors by a novel nutrient mixture in pediatric human sarcoma cell lines.
Osteosarcoma
N-?-acetyltransferase 10 protein promotes metastasis by stabilizing matrix metalloproteinase-2 protein in human osteosarcomas.
Osteosarcoma
Nifuroxazide induces apoptosis, inhibits cell migration and invasion in osteosarcoma.
Osteosarcoma
Nobiletin inhibits human osteosarcoma cells metastasis by blocking ERK and JNK-mediated MMPs expression.
Osteosarcoma
Notoginsenoside R1 counteracts mesenchymal stem cell-evoked oncogenesis and doxorubicin resistance in osteosarcoma cells by blocking IL-6 secretion-induced JAK2/STAT3 signaling.
Osteosarcoma
Oncogenic roles of astrocyte elevated gene-1 (AEG-1) in osteosarcoma progression and prognosis.
Osteosarcoma
Overexpression of matrix metalloproteinase (MMP)-9 correlates with metastatic potency of spontaneous and 4-hydroxyaminoquinoline 1-oxide (4-HAQO)-induced transplantable osteosarcomas in rats.
Osteosarcoma
Parathyroid hormone regulation of matrix degrading enzymes in rat osteoblastic osteosarcoma 17/2.8 cells.
Osteosarcoma
Pigment epithelium-derived factor upregulates collagen I and downregulates matrix metalloproteinase 2 in osteosarcoma cells, and colocalises to collagen I and heat shock protein 47 in fetal and adult bone.
Osteosarcoma
Polyoma virus-induced osteosarcomas in inbred strains of mice: host determinants of metastasis.
Osteosarcoma
Ras activation mediates WISP-1-induced increases in cell motility and matrix metalloproteinase expression in human osteosarcoma.
Osteosarcoma
Role of MMP-9 and its tissue inhibitor TIMP-1 in human osteosarcoma: findings in 42 patients followed for 1-16 years.
Osteosarcoma
Rosmarinic acid exerts an anticancer effect on osteosarcoma cells by inhibiting DJ-1 via regulation of the PTEN-PI3K-Akt signaling pathway.
Osteosarcoma
S100A4 regulates membrane induced activation of matrix metalloproteinase-2 in osteosarcoma cells.
Osteosarcoma
Selaginella tamariscina (Beauv.) possesses antimetastatic effects on human osteosarcoma cells by decreasing MMP-2 and MMP-9 secretions via p38 and Akt signaling pathways.
Osteosarcoma
Silibinin suppresses human osteosarcoma MG-63 cell invasion by inhibiting the ERK-dependent c-Jun/AP-1 induction of MMP-2.
Osteosarcoma
Small GTP-binding protein, Rho, both increased and decreased cellular motility, activation of matrix metalloproteinase 2 and invasion of human osteosarcoma cells.
Osteosarcoma
Statin-induced inhibition of 3-hydroxy-3-methyl glutaryl coenzyme a reductase sensitizes human osteosarcoma cells to anticancer drugs.
Osteosarcoma
Target-activated transcription for the amplified sensing of protease biomarkers.
Osteosarcoma
The effect of phenytoin on collagenase and gelatinase activities in UMR 106-01 rat osteoblastic osteosarcoma cells.
Osteosarcoma
The study of mechanism of miR-34c-5p targeting FLOT2 to regulate proliferation, migration and invasion of osteosarcoma cells.
Osteosarcoma
Upregulation of miR-328 and inhibition of CREB-DNA-binding activity are critical for resveratrol-mediated suppression of matrix metalloproteinase-2 and subsequent metastatic ability in human osteosarcomas.
Osteosarcoma
Visfatin triggers the in vitro migration of osteosarcoma cells via activation of NF-?B/IL-6 signals.
Otitis Media
Activities of matrix metalloproteinases and tissue inhibitor of metalloproteinase-2 in idiopathic hemotympanum and otitis media with effusion.
Otitis Media
Effect of CT manifestations of cholesteatoma on MMP-2, MMP-9 and IL-6 in the serum of patients.
Otitis Media
Expression of matrix metalloproteinase-9 and -2 in pediatric chronic otitis media with effusion.
Otitis Media with Effusion
Activities of matrix metalloproteinases and tissue inhibitor of metalloproteinase-2 in idiopathic hemotympanum and otitis media with effusion.
Otitis Media with Effusion
Expression of matrix metalloproteinase-9 and -2 in pediatric chronic otitis media with effusion.
Otitis Media with Effusion
Matrix metalloproteinases 2 and 9 in otitis media with effusion.
Ovarian Cysts
Difference in expression of matrix metalloproteinase-2 and matrix metalloproteinase-9 in patients with persistent ovarian cysts.
Ovarian Cysts
Immunoexpression of the PTEN protein and matrix metalloproteinase-2 in endometrial cysts, endometrioid and clear cell ovarian cancer.
Ovarian Cysts
Study on matrix metalloproteinase 1 and 2 gene expression and NO in dairy cows with ovarian cysts.
Ovarian Diseases
Clinical significance of serum MMP-2 and MMP-7 in patients with ovarian cancer.
Ovarian Neoplasms
37-kDa laminin receptor precursor mediates GnRH-II-induced MMP-2 expression and invasiveness in ovarian cancer cells.
Ovarian Neoplasms
9-Hydroxycanthin-6-one isolated from stem bark of Ailanthus altissima induces ovarian cancer cell apoptosis and inhibits the activation of tumor-associated macrophages.
Ovarian Neoplasms
Adenosine Inhibits Ovarian Cancer Growth Through Regulating RhoGDI2 Protein Expression.
Ovarian Neoplasms
Altered expression of metastasis-associated and regulatory molecules in effusions from breast cancer patients: a novel model for tumor progression.
Ovarian Neoplasms
Anti-tumor and chemosensitization effects of Cryptotanshinone extracted from Salvia miltiorrhiza Bge. on ovarian cancer cells in vitro.
Ovarian Neoplasms
Auraptene Inhibits Migration and Invasion of Cervical and Ovarian Cancer Cells by Repression of Matrix Metalloproteinasas 2 and 9 Activity.
Ovarian Neoplasms
BAG3 increases the invasiveness of uterine corpus carcinoma cells by suppressing miR?29b and enhancing MMP2 expression.
Ovarian Neoplasms
Baicalein inhibits MMP-2 expression in human ovarian cancer cells by suppressing the p38 MAPK-dependent NF-?B signaling pathway.
Ovarian Neoplasms
Bisphenol A induces ovarian cancer cell proliferation and metastasis through estrogen receptor-? pathways.
Ovarian Neoplasms
Calcium influx modulates expression of matrix metalloproteinase-2 (72-kDa type IV collagenase, gelatinase A).
Ovarian Neoplasms
Catalpol suppresses proliferation and facilitates apoptosis of OVCAR-3 ovarian cancer cells through upregulating microRNA-200 and downregulating MMP-2 expression.
Ovarian Neoplasms
Cathepsin B mediates the pH-dependent proinvasive activity of tumor-shed microvesicles.
Ovarian Neoplasms
Characterization of extracellular matrix-degrading proteinase and its inhibitor in gynecologic cancer tissues with clinically different metastatic form.
Ovarian Neoplasms
Characterization of gelatinases linked to extracellular matrix invasion in ovarian adenocarcinoma: purification of matrix metalloproteinase 2.
Ovarian Neoplasms
Claudin-3 and claudin-4 expression in ovarian epithelial cells enhances invasion and is associated with increased matrix metalloproteinase-2 activity.
Ovarian Neoplasms
Clinical significance of serum MMP-2 and MMP-7 in patients with ovarian cancer.
Ovarian Neoplasms
Contributions of stromal metalloproteinase-9 to angiogenesis and growth of human ovarian carcinoma in mice.
Ovarian Neoplasms
Cyclooxygenase-2 functions as a downstream mediator of lysophosphatidic acid to promote aggressive behavior in ovarian carcinoma cells.
Ovarian Neoplasms
Diet-Derived Gallated Catechins Prevent TGF-?-Mediated Epithelial-Mesenchymal Transition, Cell Migration and Vasculogenic Mimicry in Chemosensitive ES-2 Ovarian Cancer Cells.
Ovarian Neoplasms
Dihydroartiminisin inhibits the growth and metastasis of epithelial ovarian cancer.
Ovarian Neoplasms
Effect of CO2 pneumoperitoneum on the proliferation of human ovarian cancer cell line SKOV-3 and the expression of NM23-H1 and MMP-2.
Ovarian Neoplasms
Effects of synthetic peptides and protease inhibitors on the interaction of a human ovarian cancer cell line (NIH:OVCAR-3) with a reconstituted basement membrane (Matrigel).
Ovarian Neoplasms
Enhanced immunoreactivity of TIMP-2 in the stromal compartment of tumor as a marker of favorable prognosis in ovarian cancer patients.
Ovarian Neoplasms
Enhanced in vitro invasiveness of ovarian cancer cells through up-regulation of VEGF and induction of MMP-2.
Ovarian Neoplasms
ETS-1 regulates vascular endothelial growth factor-induced matrix metalloproteinase-9 and matrix metalloproteinase-13 expression in human ovarian carcinoma cell SKOV-3.
Ovarian Neoplasms
Evaluation of Matrix Metalloproteinases, Cytokines and Their Potential Role in the Development of Ovarian Cancer.
Ovarian Neoplasms
Expression of latent matrix metalloproteinase 9 (MMP-9) predicts survival in advanced ovarian cancer.
Ovarian Neoplasms
Expression of matrix metalloproteinases (MMP-2, MMP-9, MT1-MMP) and their inhibitors (TIMP-1, TIMP-2) in common epithelial tumors of the ovary.
Ovarian Neoplasms
Expression of matrix metalloproteinases-2 and -9 by cells isolated from the peritoneal fluid of women with ovarian carcinoma.
Ovarian Neoplasms
Expression of various matrix proteases and Ets family transcriptional factors in ovarian cancer cell lines: correlation to invasive potential.
Ovarian Neoplasms
Fibroblasts stimulate human ovarian cancer cell invasion and expression of 72-kDa gelatinase A (MMP-2).
Ovarian Neoplasms
Fibronectin secretion from human peritoneal tissue induces Mr 92,000 type IV collagenase expression and invasion in ovarian cancer cell lines.
Ovarian Neoplasms
Functional role of matrix metalloproteinases in ovarian tumor cell plasticity.
Ovarian Neoplasms
Gelatinase A-immunoreactive protein in ovarian lesions- prognostic value in epithelial ovarian cancer.
Ovarian Neoplasms
Gonadotropins Induce Tumor Cell Migration and Invasion by Increasing Cyclooxygenases Expression and Prostaglandin E2 Production in Human Ovarian Cancer Cells.
Ovarian Neoplasms
High expression of tissue inhibitor of metalloproteinase-2 in serous ovarian carcinomas and the role of this expression in ovarian tumorigenesis.
Ovarian Neoplasms
Hormonal regulation and distinct functions of semaphorin-3B and semaphorin-3F in ovarian cancer.
Ovarian Neoplasms
IL6-induced metastasis modulators p-STAT3, MMP-2 and MMP-9 are targets of 3,3'-diindolylmethane in ovarian cancer cells.
Ovarian Neoplasms
Immunoexpression of the PTEN protein and matrix metalloproteinase-2 in endometrial cysts, endometrioid and clear cell ovarian cancer.
Ovarian Neoplasms
In vitro modulation of MMP-2 and MMP-9 in human cervical and ovarian cancer cell lines by cytokines, inducers and inhibitors.
Ovarian Neoplasms
Increased endostatin generation and decreased angiogenesis via MMP-9 by tamoxifen in hormone dependent ovarian cancer.
Ovarian Neoplasms
Increased expression of matrix metalloproteinases (MMP)-2, MMP-9, and the urokinase-type plasminogen activator is associated with progression from benign to advanced ovarian cancer.
Ovarian Neoplasms
Increased matrix metalloproteinase-9 activity in human ovarian cancer cells cultured with conditioned medium from human peritoneal tissue.
Ovarian Neoplasms
Inhibition of matrix metalloproteinase-2 secretion and invasion by human ovarian cancer cell line SK-OV-3 with lysine, proline, arginine, ascorbic acid and green tea extract.
Ovarian Neoplasms
Knockdown of survivin contributes to antitumor activity in cisplatin-resistant ovarian cancer cells.
Ovarian Neoplasms
Lewis (y) Antigen Overexpression Increases the Expression of MMP-2 and MMP-9 and Invasion of Human Ovarian Cancer Cells.
Ovarian Neoplasms
Limited independent prognostic value of MMP-14 and MMP-2 expression in ovarian cancer.
Ovarian Neoplasms
LPA-induced epithelial ovarian cancer (EOC) in vitro invasion and migration are mediated by VEGF receptor-2 (VEGF-R2).
Ovarian Neoplasms
Lysophosphatidic acid down-regulates stress fibers and up-regulates pro-matrix metalloproteinase-2 activation in ovarian cancer cells.
Ovarian Neoplasms
Magnolol down-regulates HER2 gene expression, leading to inhibition of HER2-mediated metastatic potential in ovarian cancer cells.
Ovarian Neoplasms
Matrilysin (MMP-7) promotes invasion of ovarian cancer cells by activation of progelatinase.
Ovarian Neoplasms
Matrix metalloproteinase-9 expression correlates with prognosis and involved in ovarian cancer cell invasion.
Ovarian Neoplasms
Matrix metalloproteinases 2, 7, and 9 and tissue inhibitor of metalloproteinases-1 in tumors and serum of patients with ovarian neoplasms.
Ovarian Neoplasms
Membrane-type matrix metalloproteinase expression and matrix metalloproteinase-2 activation in primary human ovarian epithelial carcinoma cells.
Ovarian Neoplasms
MicroRNA-205 promotes cell invasion by repressing TCF21 in human ovarian cancer.
Ovarian Neoplasms
miR-17 inhibits ovarian cancer cell peritoneal metastasis by targeting ITGA5 and ITGB1.
Ovarian Neoplasms
Mixed lineage kinase 3 is required for matrix metalloproteinase expression and invasion in ovarian cancer cells.
Ovarian Neoplasms
MLK4? functions as a negative regulator of MAPK signaling and cell invasion.
Ovarian Neoplasms
MMP-2 functions as an early response protein in ovarian cancer metastasis.
Ovarian Neoplasms
MMP-2 mRNA Expression in Ovarian Cancer Tissues Predicts Patients' Response to Platinum-Taxane Chemotherapy.
Ovarian Neoplasms
Notch1 Affects Chemo-resistance Through Regulating Epithelial-Mesenchymal Transition (EMT) in Epithelial Ovarian cancer cells.
Ovarian Neoplasms
Novel functions for 2-phenylbenzimidazole-5-sulphonic acid: Inhibition of ovarian cancer cell responses and tumour angiogenesis.
Ovarian Neoplasms
Ovarian carcinoma cell cultures are resistant to TGF-beta1-mediated growth inhibition despite expression of functional receptors.
Ovarian Neoplasms
Oxytocin inhibits ovarian cancer metastasis by repressing the expression of MMP-2 and VEGF.
Ovarian Neoplasms
p21-Activated kinase 4 regulates ovarian cancer cell proliferation, migration, and invasion and contributes to poor prognosis in patients.
Ovarian Neoplasms
Pathological and prognostic significance of matrix metalloproteinase-2 expression in ovarian cancer: a meta-analysis.
Ovarian Neoplasms
Primary Ovarian Tumors With Lymphogenic and Hematogenic Metastasis Express High MMP-14, Which Colocalizes With Highly Sulfated Chondroitin Sulfate in the Stroma.
Ovarian Neoplasms
Prognostic significance of stromal metalloproteinase-2 in ovarian adenocarcinoma and its relation to carcinoma progression.
Ovarian Neoplasms
Prognostic value of MMP-2 for patients with ovarian epithelial carcinoma: a systematic review and meta-analysis.
Ovarian Neoplasms
Quercetin attenuates metastatic ability of human metastatic ovarian cancer cells via modulating multiple signaling molecules involved in cell survival, proliferation, migration and adhesion.
Ovarian Neoplasms
Relationship between the expression of VEGF signal components and matrix metalloproteinases in ovarian tumors.
Ovarian Neoplasms
Role of immunohistochemical overexpression of matrix metalloproteinases MMP-2 and MMP-11 in the prognosis of death by ovarian cancer.
Ovarian Neoplasms
Selective mediation of ovarian cancer SKOV3 cells death by pristine carbon quantum dots/Cu2O composite through targeting matrix metalloproteinases, angiogenic cytokines and cytoskeleton.
Ovarian Neoplasms
Shed membrane fragment-associated markers for endometrial and ovarian cancers.
Ovarian Neoplasms
Small integrin binding ligand N-linked glycoprotein gene family expression in different cancers.
Ovarian Neoplasms
Stromal-cell derived factor-1 regulates epithelial ovarian cancer cell invasion by activating matrix metalloproteinase-9 and matrix metalloproteinase-2.
Ovarian Neoplasms
TGFbeta1 stimulates the secretion of matrix metalloproteinase 2 (MMP2) and the invasive behavior in human ovarian cancer cells, which is suppressed by MMP inhibitor BB3103.
Ovarian Neoplasms
The anti-tumor effect and bioactive phytochemicals of Hedyotis diffusa willd on ovarian cancer cells.
Ovarian Neoplasms
The C3G/Rap1 pathway promotes secretion of MMP-2 and MMP-9 and is involved in serous ovarian cancer metastasis.
Ovarian Neoplasms
The expression of tumor-derived and stromal-derived matrix metalloproteinase 2 predicted prognosis of ovarian cancer.
Ovarian Neoplasms
The initial steps of ovarian cancer cell metastasis are mediated by MMP-2 cleavage of vitronectin and fibronectin.
Ovarian Neoplasms
The leukotriene B4 receptor-2 promotes invasiveness and metastasis of ovarian cancer cells through STAT3-dependent up-regulation of matrix metalloproteinase 2.
Ovarian Neoplasms
The levels of trypsinogen isoenzymes in ovarian tumour cyst fluids are associated with promatrix metalloproteinase-9 but not promatrix metalloproteinase-2 activation.
Ovarian Neoplasms
The relevance and role of vascular endothelial growth factor C, matrix metalloproteinase-2 and E-cadherin in epithelial ovarian cancer.
Ovarian Neoplasms
The role of p53 protein and MMP-2 tumor/stromal cells expression on progressive growth of ovarian neoplasms.
Ovarian Neoplasms
The value of sequential serum measurements of gelatinases and tissue inhibitors during chemotherapy in ovarian cancer.
Ovarian Neoplasms
Tissue transglutaminase regulates MMP-2 in ovarian cancer by modulating CREB activity.
Ovarian Neoplasms
Tumor-associated macrophages promote invasion via Toll-like receptors signaling in patients with ovarian cancer.
Ovarian Neoplasms
Urinary MMP-2 and MMP-9 predict the presence of ovarian cancer in women with normal CA125 levels.
Ovarian Neoplasms
Vascular endothelial growth factor activating matrix metalloproteinase in ascitic fluid during peritoneal dissemination of ovarian cancer.
Ovarian Neoplasms
WFDC2 contributes to epithelial-mesenchymal transition (EMT) by activating AKT signaling pathway and regulating MMP-2 expression.
Ovarian Neoplasms
[Assessment of prognostic factors in common ovarian tumors of varying malignancy]
Ovarian Neoplasms
[Association of SNPs in the promoter of MMP-2 and TIMP-2 genes with epithelial ovarian cancer]
Ovarian Neoplasms
[Correlation of vasculogenic mimicry with clinicopathologic features and prognosis of ovarian carcinoma]
Ovarian Neoplasms
[Elevated expression of matrix metalloproteinase-9, and fibronectin concentration in recurrent epithelial ovarian cancer]
Ovarian Neoplasms
[Expression of matrix metaloproteinase and tissue inhibitors in ovarian tumors]
Ovarian Neoplasms
[Fibronectin induces matrix metalloproteinase-2 expression in ovarian cancer cells]
Ovarian Neoplasms
[Preliminary study of dihydroartemisin in inhibiting invasion and metastasis of hepatoma cells].
Ovarian Neoplasms
[Preparation, identification and application of monoclonal antibody against matrix metalloproteinases-2].
Overweight
Adipocytes contribute to the growth and progression of multiple myeloma: Unraveling obesity related differences in adipocyte signaling.
Overweight
Increase in MMP-2 activity in overweight and obese women is associated with menopausal status.
Pancreatic Neoplasms
?-Mangostin suppresses lipopolysaccharide-induced invasion by inhibiting matrix metalloproteinase-2/9 and increasing E-cadherin expression through extracellular signal-regulated kinase signaling in pancreatic cancer cells.
Pancreatic Neoplasms
?2-AR-HIF-1?: a novel regulatory axis for stress-induced pancreatic tumor growth and angiogenesis.
Pancreatic Neoplasms
An MMP-2 Responsive Liposome Integrating Antifibrosis and Chemotherapeutic Drugs for Enhanced Drug Perfusion and Efficacy in Pancreatic Cancer.
Pancreatic Neoplasms
Antiangiogenic effect of somatostatin receptor subtype 2 on pancreatic cancer cell line: Inhibition of vascular endothelial growth factor and matrix metalloproteinase-2 expression in vitro.
Pancreatic Neoplasms
Antidiabetic thiazolidinediones inhibit invasiveness of pancreatic cancer cells via PPARgamma independent mechanisms.
Pancreatic Neoplasms
Antitumor effect of a new selective matrix metalloproteinase inhibitor, MMI-166, on experimental pancreatic cancer.
Pancreatic Neoplasms
BMP2 induces PANC-1 cell invasion by MMP-2 overexpression through ROS and ERK.
Pancreatic Neoplasms
Bone morphogenetic proteins induce pancreatic cancer cell invasiveness through a Smad1-dependent mechanism that involves matrix metalloproteinase-2.
Pancreatic Neoplasms
Cantharidin represses invasion of pancreatic cancer cells through accelerated degradation of MMP2 mRNA.
Pancreatic Neoplasms
Chlorotoxin-Fc fusion inhibits release of MMP-2 from pancreatic cancer cells.
Pancreatic Neoplasms
Comprehensively enhanced delivery cascade by transformable beaded nanofibrils for pancreatic cancer therapy.
Pancreatic Neoplasms
Correlation between B7-H3 expression and matrix metalloproteinases 2 expression in pancreatic cancer.
Pancreatic Neoplasms
Correlation between protein expression of PTEN in human pancreatic cancer and the proliferation, infiltration, metastasis and prognosis.
Pancreatic Neoplasms
Corrigendum: The assessment of serum and diagnostic peritoneal lavage concentration of matrix metalloproteinase-2, matrix metalloproteinase-9, carbohydrate antigen 19-9, and carcinoembryonic antigen in patients with pancreatic cancer and chronic pancreatitis, Journal of Physiology and Pharmacology 2020 Oct; 71(5): 689.
Pancreatic Neoplasms
Curcumin inhibits H2O2-induced invasion and migration of human pancreatic cancer via suppression of the ERK/NF-?B pathway.
Pancreatic Neoplasms
Detection of matrix metalloproteinase activity in human pancreatic cancer.
Pancreatic Neoplasms
Differential Diagnosis of Autoimmune Pancreatitis From Pancreatic Cancer by Analysis of Serum Gelatinase Levels.
Pancreatic Neoplasms
Downregulation of miR-21 inhibits the malignant phenotype of pancreatic cancer cells by targeting VHL.
Pancreatic Neoplasms
Effects of IL-6 and AG490 on regulation of Stat3 signaling pathway and invasion of human pancreatic cancer cells in vitro.
Pancreatic Neoplasms
EGF promotes invasion by PANC-1 cells through Rac1/ROS-dependent secretion and activation of MMP-2.
Pancreatic Neoplasms
Epithelial MMP-2 expression correlates with worse prognosis in pancreatic cancer.
Pancreatic Neoplasms
EVALUATING MMP-2 AND TGFß-RI EXPRESSION IN CIRCULATING TUMOR CELLS OF PANCREATIC CANCER PATIENTS AND THEIR CORRELATION WITH CLINICAL EVOLUTION.
Pancreatic Neoplasms
Expression and in-situ localization of genes coding for extracellular matrix proteins and extracellular matrix degrading proteases in pancreatic cancer.
Pancreatic Neoplasms
Expression of integrin alphaVbeta3 in pancreatic carcinoma: relation to MMP-2 activation and lymph node metastasis.
Pancreatic Neoplasms
Expression of matrix metalloproteinases 1 and 2 genes in a possible association with metastatic abilities of human pancreatic cancer cells.
Pancreatic Neoplasms
Expression of Matrix Metalloproteinases-2/-9 is Associated With Microvessel Density in Pancreatic Cancer.
Pancreatic Neoplasms
Expression of receptor for advanced glycation end products (RAGE) and MMP-9 in human pancreatic cancer cells.
Pancreatic Neoplasms
Extraction of type IV collagenase/gelatinase from plasma membranes of human pancreatic cancer cells.
Pancreatic Neoplasms
Ginsenoside Rg3 inhibition of vasculogenic mimicry in pancreatic cancer through downregulation of VE?cadherin/EphA2/MMP9/MMP2 expression.
Pancreatic Neoplasms
Glucose transporter-1 gene expression is associated with pancreatic cancer invasiveness and MMP-2 activity.
Pancreatic Neoplasms
GSK3? mediates pancreatic cancer cell invasion in vitro via the CXCR4/MMP-2 Pathway.
Pancreatic Neoplasms
HIF1 Contributes to Hypoxia-Induced Pancreatic Cancer Cells Invasion via Promoting QSOX1 Expression.
Pancreatic Neoplasms
Histologic features of venous invasion, expression of vascular endothelial growth factor and matrix metalloproteinase-2 and matrix metalloproteinase-9, and the relation with liver metastasis in pancreatic cancer.
Pancreatic Neoplasms
Hypoxia-reoxygenation increase invasiveness of PANC-1 cells through Rac1/MMP-2.
Pancreatic Neoplasms
In vitro and in vivo matrix metalloproteinase production by pancreatic cancer cells and by distant organs.
Pancreatic Neoplasms
Induction of pancreatic cancer cell apoptosis, invasion, migration, and enhancement of chemotherapy sensitivity of gemcitabine, 5-FU, and oxaliplatin by hnRNP A2/B1 siRNA.
Pancreatic Neoplasms
Inhibition and mechanism of action of a protease inhibitor in human pancreatic cancer cells.
Pancreatic Neoplasms
Interaction between cancer cells and stromal fibroblasts is required for activation of the uPAR-uPA-MMP-2 cascade in pancreatic cancer metastasis.
Pancreatic Neoplasms
Investigation of juglone effects on metastasis and angiogenesis in pancreatic cancer cells.
Pancreatic Neoplasms
Involvement of ephrin receptor A4 in pancreatic cancer cell motility and invasion.
Pancreatic Neoplasms
KAI1 is a potential target for anti-metastasis in pancreatic cancer cells.
Pancreatic Neoplasms
Matrine inhibiting pancreatic cells epithelial-mesenchymal transition and invasion through ROS/NF-?B/MMPs pathway.
Pancreatic Neoplasms
Matrix metalloproteinase 2 (MMP-2) and its tissue inhibitor 2 (TIMP-2) in pancreatic cancer (PC).
Pancreatic Neoplasms
Matrix metalloproteinase inhibition suppresses MMP-2 activity and activation of PANC-1 cells in vitro.
Pancreatic Neoplasms
Matrix metalloproteinase inhibitor RO 28-2653 decreases liver metastasis by reduction of MMP-2 and MMP-9 concentration in BOP-induced ductal pancreatic cancer in Syrian Hamsters: inhibition of matrix metalloproteinases in pancreatic cancer.
Pancreatic Neoplasms
Matrix metalloproteinase-14 is a mechanically regulated activator of secreted MMPs and invasion.
Pancreatic Neoplasms
Matrix metalloproteinase-2 in pancreatic juice for diagnosis of pancreatic cancer.
Pancreatic Neoplasms
Matrix metalloproteinases and their role in pancreatic cancer: a review of preclinical studies and clinical trials.
Pancreatic Neoplasms
miR-221/222 induces pancreatic cancer progression through the regulation of matrix metalloproteinases.
Pancreatic Neoplasms
MMP-2 and TIMP-1 are derived from, not in response to, pancreatic cancer.
Pancreatic Neoplasms
Nerve growth factor stimulates MMP-2 expression and activity and increases invasion by human pancreatic cancer cells.
Pancreatic Neoplasms
NRAGE suppresses metastasis of melanoma and pancreatic cancer in vitro and in vivo.
Pancreatic Neoplasms
Overexpression and biological function of MEF2D in human pancreatic cancer.
Pancreatic Neoplasms
Overexpression of Nodal induces a metastatic phenotype in pancreatic cancer cells via the Smad2/3 pathway.
Pancreatic Neoplasms
Overexpression of the SMYD3 Promotes Proliferation, Migration, and Invasion of Pancreatic Cancer.
Pancreatic Neoplasms
p202, an interferon-inducible protein, mediates multiple antitumor activities in human pancreatic cancer xenograft models.
Pancreatic Neoplasms
Pancreatic stellate cells are an important source of MMP-2 in human pancreatic cancer and accelerate tumor progression in a murine xenograft model and CAM assay.
Pancreatic Neoplasms
Peroxisome proliferator-activated receptor gamma ligand inhibits cell growth and invasion of human pancreatic cancer cells.
Pancreatic Neoplasms
Peroxisome proliferator-activated receptor-? inhibits pancreatic cancer cell invasion and metastasis via regulating MMP-2 expression through PTEN.
Pancreatic Neoplasms
PHGDH is an independent prognosis marker and contributes cell proliferation, migration and invasion in human pancreatic cancer.
Pancreatic Neoplasms
Potential involvement of IL-8 and its receptors in the invasiveness of pancreatic cancer cells.
Pancreatic Neoplasms
Prognostic significance of plasma matrix metalloprotease-2 in pancreatic cancer patients.
Pancreatic Neoplasms
Prostaglandin E2 enhances pancreatic cancer invasiveness through an Ets-1-dependent induction of matrix metalloproteinase-2.
Pancreatic Neoplasms
Protease-activated receptor 2 agonist increases cell proliferation and invasion of human pancreatic cancer cells.
Pancreatic Neoplasms
Psoriasin promotes invasion, aggregation and survival of pancreatic cancer cells; association with disease progression.
Pancreatic Neoplasms
Ratiometric Activatable Cell-Penetrating Peptides Label Pancreatic Cancer, Enabling Fluorescence-Guided Surgery, Which Reduces Metastases and Recurrence in Orthotopic Mouse Models.
Pancreatic Neoplasms
RECK expression in pancreatic cancer: its correlation with lower invasiveness and better prognosis.
Pancreatic Neoplasms
Reduction of in vivo tumor growth by MMI-166, a selective matrix metalloproteinase inhibitor, through inhibition of tumor angiogenesis in squamous cell carcinoma cell lines of head and neck.
Pancreatic Neoplasms
SDF-1? upregulation of MMP-2 is mediated by p38 MAPK signaling in pancreatic cancer cell lines.
Pancreatic Neoplasms
Selection of peptide inhibitor to matrix metalloproteinase-2 using phage display and its effects on pancreatic cancer cell lines PANC-1 and CFPAC-1.
Pancreatic Neoplasms
Suppression of matrix metalloproteinase-2 via RNA interference inhibits pancreatic carcinoma cell invasiveness and adhesion.
Pancreatic Neoplasms
TGF-?1 increases invasiveness of SW1990 cells through Rac1/ROS/NF-?B/IL-6/MMP-2.
Pancreatic Neoplasms
TGF-beta-induced invasiveness of pancreatic cancer cells is mediated by matrix metalloproteinase-2 and the urokinase plasminogen activator system.
Pancreatic Neoplasms
The assessment of serum and diagnostic peritoneal lavage concentration of matrix metalloproteinase-2, matrix metalloproteinase-9, carbohydrate antigen 19-9, and carcinoembryonic antigen in patients with pancreatic cancer and chronic pancreatitis.
Pancreatic Neoplasms
TIMP-1 antisense gene transfection attenuates the invasive potential of pancreatic cancer cells in vitro and inhibits tumor growth in vivo.
Pancreatic Neoplasms
TIMP-1 overexpression in pancreatic cancer attenuates tumor growth, decreases implantation and metastasis, and inhibits angiogenesis.
Pancreatic Neoplasms
TM4SF1 Regulates Pancreatic Cancer Migration and Invasion In Vitro and In Vivo.
Pancreatic Neoplasms
Transcriptomic Analyses and Potential Therapeutic Targets of Pancreatic Cancer With Concomitant Diabetes.
Pancreatic Neoplasms
Transient gene silencing of galectin-3 suppresses pancreatic cancer cell migration and invasion through degradation of ?-catenin.
Pancreatic Neoplasms
Two-dimensional zymography for analysis of proteolytic enzymes in human pure pancreatic juice.
Pancreatic Neoplasms
Ukrain Affects Pancreas Cancer Cell Phenotype in vitro by Targeting MMP-9 and Intra-/Extracellular SPARC Expression.
Pancreatic Neoplasms
Upregulation of ARHGAP30 attenuates pancreatic cancer progression by inactivating the ?-catenin pathway.
Pancreatic Neoplasms
ZIP4 upregulates the expression of neuropilin-1, vascular endothelial growth factor, and matrix metalloproteases in pancreatic cancer cell lines and xenografts.
Pancreatic Neoplasms
[Effect of hypoxia on production and secretion of matrix metalloproteinases in tumor cells]
Pancreatic Neoplasms
[Effect of RNAi-mediated STAT3 gene inhibition on metastasis of human pancreatic cancer cells]
Pancreatic Neoplasms
[Inhibitory effect of AG490 on invasion and metastasis of human pancreatic cancer cells in vitro]
Pancreatic Neoplasms
[The mechanism of KAI1 gene in inhibition of metastasis of primary pancreatic cancer]
Pancreatitis
Associations of MMP-2 and MMP-9 gene polymorphism with ulinastatin efficacy in patients with severe acute pancreatitis.
Pancreatitis
Editorial: Acute pancreatitis and neutrophil gelatinase MMP9: don't get me started!
Pancreatitis
Hypertonic Saline Reduces Metalloproteinase Expression In Liver During Pancreatitis.
Pancreatitis
In vivo activation of gelatinase B/MMP-9 by trypsin in acute pancreatitis is a permissive factor in streptozotocin-induced diabetes.
Pancreatitis
Increased gelatinase B/matrix metalloproteinase 9 (MMP-9) activity in a murine model of acute coxsackievirus B4-induced pancreatitis.
Pancreatitis
Increased matrix metalloproteinase expression and activation following experimental acute pancreatitis.
Pancreatitis
Long-term overexpression of membrane type-1 matrix metalloproteinase and matrix metalloproteinase-2 in oleic acid-induced pancreatitis in rats.
Pancreatitis
MMP-2 and MMP-9 gene polymorphisms act as biological indicators for ulinastatin efficacy in patients with severe acute pancreatitis.
Pancreatitis
Persistent destruction of the basement membrane of the pancreatic duct contributes to progressive acinar atrophy in rats with experimentally induced pancreatitis.
Pancreatitis
Role of TGF-beta1, extracellular matrix, and matrix metalloproteinase in the healing process of the pancreas after induction of acute necrotizing pancreatitis using arginine in rats.
Pancreatitis
The influence of transforming growth factor beta 1 on the expression of genes coding for matrix metalloproteinases and tissue inhibitors of metalloproteinases during regeneration from cerulein-induced pancreatitis.
Pancreatitis, Chronic
Balance of expression of genes coding for extracellular matrix proteins and extracellular matrix degrading proteases in chronic pancreatitis.
Pancreatitis, Chronic
Corrigendum: The assessment of serum and diagnostic peritoneal lavage concentration of matrix metalloproteinase-2, matrix metalloproteinase-9, carbohydrate antigen 19-9, and carcinoembryonic antigen in patients with pancreatic cancer and chronic pancreatitis, Journal of Physiology and Pharmacology 2020 Oct; 71(5): 689.
Pancreatitis, Chronic
Differences in Pancreatic Immunohistochemical Staining Profiles of TGF-beta1, MMP-2, and TIMP-2 Between Autoimmune and Alcoholic Chronic Pancreatitis.
Pancreatitis, Chronic
Differential Diagnosis of Autoimmune Pancreatitis From Pancreatic Cancer by Analysis of Serum Gelatinase Levels.
Pancreatitis, Chronic
Immunohistochemical study of transforming growth factor-beta 1, matrix metalloproteinase-2,9, tissue inhibitors of metalloproteinase-1,2, and basement membrane components at pancreatic ducts in chronic pancreatitis.
Pancreatitis, Chronic
Involvement of matrix metalloproteinase-2 activity in invasion and metastasis of pancreatic carcinoma.
Pancreatitis, Chronic
Matrix metalloproteinase-2 in pancreatic juice for diagnosis of pancreatic cancer.
Pancreatitis, Chronic
Prognostic significance of plasma matrix metalloprotease-2 in pancreatic cancer patients.
Pancreatitis, Chronic
Role of MMP-2 and MMP-9 and their natural inhibitors in liver fibrosis, chronic pancreatitis and non-specific inflammatory bowel diseases.
Pancreatitis, Chronic
The assessment of serum and diagnostic peritoneal lavage concentration of matrix metalloproteinase-2, matrix metalloproteinase-9, carbohydrate antigen 19-9, and carcinoembryonic antigen in patients with pancreatic cancer and chronic pancreatitis.
Papilloma
Expression of matrix metalloproteinases (MMP-2 and MMP-9) in recurrent respiratory papillomas and laryngeal carcinoma: clinical and morphological parallels.
Papilloma
Imatinib-associated matrix metalloproteinase suppression in p16-positive squamous cell carcinoma compared to HPV-negative HNSCC cells in vitro.
Papilloma
Immunohistochemical study on the expression of matrix metalloproteinase 2 and high-risk human papilloma virus in the malignant progression of papillomas.
Papilloma
Increased expression of matrix metalloproteinase-2 and 9 and human papilloma virus infection are associated with malignant transformation of sinonasal inverted papilloma.
Papilloma
Paracrine communication between malignant and non-malignant prostate epithelial cells in culture alters growth rate, matrix protease secretion and in vitro invasion.
Papilloma
The expression of epidermal growth factor receptor, vascular endothelial growth factor, matrix metalloproteinase-2, and cyclooxygenase-2 in relation to human papilloma viral load and persistence of human papillomavirus after conization with negative margins.
Papilloma, Inverted
Increased expression of matrix metalloproteinase-2 and 9 and human papilloma virus infection are associated with malignant transformation of sinonasal inverted papilloma.
Papilloma, Inverted
Matrix metalloproteinase-2 and -9 expression in sinonasal inverted papilloma.
Papillomavirus Infections
Matrix metalloproteinase-2, squamous cell carcinoma antigen, and tissue polypeptide-specific antigen expression in Egyptian patients with cervical carcinoma: Relationship with prognosis.
Papillomavirus Infections
The protective role of the -1306C>T functional polymorphism in matrix metalloproteinase-2 gene is associated with cervical cancer: implication of human papillomavirus infection.
Paracoccidioidomycosis
Matrix metalloproteinases with gelatinolytic activity induced by Paracoccidioides brasiliensis infection.
Paralysis
HMGB1 inhibitor glycyrrhizin attenuates intracerebral hemorrhage-induced injury in rats.
Paralysis
Selective localization of gelatinase A, an enzyme degrading beta-amyloid protein, in white matter microglia and in Schwann cells.
Paraparesis, Spastic
Selective matrix metalloproteinase inhibitor, N-biphenyl sulfonyl phenylalanine hydroxamic acid, inhibits the migration of CD4+ T lymphocytes in patients with HTLV-I-associated myelopathy.
Paraparesis, Tropical Spastic
Expression of metalloproteinase-2 (gelatinase A) in labial salivary glands of patients with Sjögren's syndrome with HTLV-I infection.
Paraparesis, Tropical Spastic
Selective matrix metalloproteinase inhibitor, N-biphenyl sulfonyl phenylalanine hydroxamic acid, inhibits the migration of CD4+ T lymphocytes in patients with HTLV-I-associated myelopathy.
Paraparesis, Tropical Spastic
Vascular cell adhesion molecule-1-mediated matrix metalloproteinase-2 induction in peripheral blood T cells is up-regulated in patients with HTLV-I-associated myelopathy.
Paraproteinemias
Proteolytic activity of human lymphoid tumor cells. Correlation with tumor progression.
Parapsoriasis
Matrix metalloproteinase-2 promoter genotype as a marker of cutaneous T-cell lymphoma early stage.
Parathyroid Neoplasms
Expression of matrix metalloproteinase gelatinase A messenger ribonucleic acid in parathyroid carcinomas.
Parkinson Disease
Expression of MMP-2, MMP-9, and MMP-1 and their endogenous counterregulators TIMP-1 and TIMP-2 in postmortem brain tissue of Parkinson's disease.
Parotitis
Decreased salivary matrix metalloproteinase-8 reflecting a defensive potential in juvenile parotitis.
Pediatric Obesity
Effect of metabolic syndrome risk factors and MMP-2 genetic variations on circulating MMP-2 levels in childhood obesity.
Pelvic Inflammatory Disease
Significant elevation and correlation of plasma neutrophil gelatinase associated lipocalin and its complex with matrix metalloproteinase-9 in patients with pelvic inflammatory disease.
Pelvic Inflammatory Disease
Significant elevation of plasma matrix metalloproteinase-9 level and its ratio to matrix metalloproteinase-2 in patients with pelvic inflammatory disease.
Pemphigoid, Benign Mucous Membrane
Neutrophil Collagenase, Gelatinase, and Myeloperoxidase in Tears of Patients with Stevens-Johnson Syndrome and Ocular Cicatricial Pemphigoid.
Pemphigoid, Bullous
92-kD gelatinase is produced by eosinophils at the site of blister formation in bullous pemphigoid and cleaves the extracellular domain of recombinant 180-kD bullous pemphigoid autoantigen.
Pemphigoid, Bullous
Gelatinase B-deficient mice are resistant to experimental bullous pemphigoid.
Pemphigoid, Bullous
Increased expression of matrix metalloproteinase-2, matrix metalloproteinase-9 and matrix metalloproteinase-13 in lesional skin of bullous pemphigoid.
Penile Neoplasms
E-cadherin, MMP-2, and MMP-9 as prognostic markers in penile cancer: Analysis of 125 patients.
Peri-Implantitis
LOX-1 is involved in IL-1? production and extracellular matrix breakdown in dental peri-implantitis.
Peri-Implantitis
Microbiological Profile and Human Immune Response Associated with Peri-Implantitis: A Systematic Review.
Periapical Abscess
The zymographic evaluation of gelatinase (MMP-2 and -9) levels in acute and chronic periapical abscesses.
Periapical Diseases
Sonic extracts from a bacterium related to periapical disease activate gelatinase A and inactivate tissue inhibitor of metalloproteinases TIMP-1 and TIMP-2.
Periapical Granuloma
Gene-expression analysis of matrix metalloproteinases 1 and 2 and their tissue inhibitors in chronic periapical inflammatory lesions.
Periapical Granuloma
Metalloproteinases 2 and 9 Immunoexpression in Periapical Lesions from Primary Endodontic Infection: Possible Relationship with the Histopathological Diagnosis and the Presence of Pain.
Periapical Periodontitis
Decreased levels of matrix metalloproteinase-2 in root-canal exudates during root canal treatment.
Periapical Periodontitis
Expression of Matrix Metalloproteinases and Tissue Inhibitor of Matrix Metalloproteinases during Apical Periodontitis Development.
Periapical Periodontitis
Immunolocalization of matrix metalloproteinases-2 and -9 during apical periodontitis development.
Periapical Periodontitis
Resveratrol Suppresses Matrix Metalloproteinase-2 Activation Induced by Lipopolysaccharide in Mouse Osteoblasts via Interactions with AMP-Activated Protein Kinase and Suppressor of Cytokine Signaling 1.
Periapical Periodontitis
The virulence factor GroEL promotes gelatinase secretion from cells in the osteoblast lineage: Implication for direct crosstalk between bacteria and adult cells.
Pericardial Effusion
Lesions of the pericardium and their significance in the aetiology of heart failure in broiler chickens.
Periodontal Attachment Loss
Collagenolytic enzymes in gingival crevicular fluid as diagnostic indicators of periodontitis.
Periodontal Attachment Loss
Host enzymes in gingival crevicular fluid as diagnostic indicators of periodontitis.
Periodontal Diseases
Analysis of in situ protease activity in chronic adult periodontitis patients: expression of activated MMP-2 and a 40 kDa serine protease.
Periodontal Diseases
Circulating matrix metalloproteinase-8 (MMP-8) and MMP-9 are increased in chronic periodontal disease and decrease after non-surgical periodontal therapy.
Periodontal Diseases
Effects of therapy with two combinations of antibiotics on the imbalance of MMP-2÷TIMP-2 in chronic periodontitis.
Periodontal Diseases
Genetic variations in the human gelatinase A (matrix metalloproteinase-2) promoter are not associated with susceptibility to, and severity of, chronic periodontitis.
Periodontal Diseases
Gingival crevicular fluid gelatinase and its relationship to periodontal disease in human subjects.
Periodontal Diseases
Identification of polymorphonuclear leukocyte collagenase and gelatinase activities in mouthrinse samples: correlation with periodontal disease activity in adult and juvenile periodontitis.
Periodontal Diseases
Immunolocalization of matrix metalloproteinases and TIMP-1 (tissue inhibitor of metalloproteinases) in human gingival tissues from periodontitis patients.
Periodontal Diseases
Local and systemic factors in periodontal disease increase matrix-degrading enzyme activities in rat gingiva: effect of micocycline therapy.
Periodontal Diseases
MMP-2 activation by Actinobacillus actinomycetemcomitans supernatant in human PDL cells was corresponded with reduction of TIMP-2.
Periodontal Diseases
Periodontal disease, peri-implant disease and levels of salivary biomarkers IL-1?, IL-10, RANK, OPG, MMP-2, TGF-? and TNF-?: follow-up over 5 years.
Periodontal Diseases
Suppressive effect of ethanolic Kaempferia pandurata Roxb. extract on matrix metalloproteinase-2 expression in Porphyromonas gingivalis-treated human gingival fibroblasts in vitro.
Periodontal Diseases
The influence of type I diabetes mellitus on the expression and activity of gelatinases (matrix metalloproteinases-2 and -9) in induced periodontal disease.
Periodontal Diseases
Up-regulation of osteolytic mediators in human osteosarcoma cells stimulated with nicotine.
Periodontitis
Altered gene expression in leukocyte transendothelial migration and cell communication pathways in periodontitis-affected gingival tissues.
Periodontitis
Analysis of matrix metalloproteinase (MMP-8 and MMP-2) activity in gingival crevicular fluid from children with Down's syndrome.
Periodontitis
Assessment of MMP-1, MMP-8 and TIMP-2 in experimental periodontitis treated with kaempferol.
Periodontitis
Assessment of the involvement of the macrophage migration inhibitory factor-glucocorticoid regulatory dyad in the expression of matrix metalloproteinase-2 during periodontitis.
Periodontitis
Association of MMP-2-753C>T and MMP-9-1562C>T Polymorphisms with Chronic/Aggressive Periodontitis Risk: A Systematic Review and Meta-Analysis.
Periodontitis
Azilsartan increases levels of IL-10, down-regulates MMP-2, MMP-9, RANKL/RANK, Cathepsin K and up-regulates OPG in an experimental periodontitis model.
Periodontitis
Carvedilol decrease IL-1? and TNF-?, inhibits MMP-2, MMP-9, COX-2, and RANKL expression, and up-regulates OPG in a rat model of periodontitis.
Periodontitis
Detection of Enterococcus faecalis in subgingival biofilms of healthy, gingivitis, and chronic periodontitis subjects.
Periodontitis
Effect of telmisartan on levels of IL-1, TNF-?, down-regulated COX-2, MMP-2, MMP-9 and RANKL/RANK in an experimental periodontitis model.
Periodontitis
Efficacy test of horse chestnut leaf extract (ALH-L1005) as matrix metalloproteinase inhibitors in ligature-induced periodontitis in canine model.
Periodontitis
EVALUATION OF BONE RESORPTIVE POTENTIAL IN THE TREATMENT OF GENERALIZED PERIODONTITIS.
Periodontitis
Expression of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) in healthy and diseased human gingiva.
Periodontitis
Expression of matrix metalloproteinases-2, -9 and reversion-inducing cysteine-rich protein with Kazal motifs in gingiva in periodontal health and disease.
Periodontitis
Gelatinases and extracellular matrix metalloproteinase inducer are associated with cyclosporin-A-induced attenuation of periodontal degradation in rats.
Periodontitis
Genetic Factors and the Risk of Periodontitis Development: Findings from a Systematic Review Composed of 13 Studies of Meta-Analysis with 71,531 Participants.
Periodontitis
Genetic variations in the human gelatinase A (matrix metalloproteinase-2) promoter are not associated with susceptibility to, and severity of, chronic periodontitis.
Periodontitis
Interaction between the Wnt/?-catenin signaling pathway and the EMMPRIN/MMP-2, 9 route in periodontitis.
Periodontitis
Levels of metalloproteinase-2 and -9 and tissue inhibitor of matrix metalloproteinase-1 in gingival crevicular fluid of patients with periodontitis, gingivitis, and healthy gingiva.
Periodontitis
Loss of alveolar bone density in postmenopausal, osteopenic women is associated with circulating levels of gelatinases.
Periodontitis
Matrix metalloproteinase-2 may be involved with increased bone loss associated with experimental periodontitis and smoking: a study in rats.
Periodontitis
Matrix metalloproteinase-2, -9, and tissue inhibitor of MMP-2 gene polymorphisms in Taiwanese periodontitis patients.
Periodontitis
Matrix metalloproteinases (MMP-2 and MMP-9) of the oral cavity: cellular origin and relationship to periodontal status.
Periodontitis
Matrix metalloproteinases and their inhibitors in gingival crevicular fluid and saliva of periodontitis patients.
Periodontitis
Matrix metalloproteinases and their inhibitors in gingival mast cells in persons with and without human immunodeficiency virus infection.
Periodontitis
Membrane type (MT) 1-matrix metalloproteinase (MMP) and MMP-2 expression in ligature-induced periodontitis in the rat.
Periodontitis
MMP-2, MMP-9 and TIMP-2 gene polymorphisms in Chinese patients with generalized aggressive periodontitis.
Periodontitis
Multiple forms of gelatinases/type IV collagenases in saliva and gingival crevicular fluid of periodontitis patients.
Periodontitis
Olmesartan decreases IL-1? and TNF-? levels; downregulates MMP-2, MMP-9, COX-2, and RANKL; and upregulates OPG in experimental periodontitis.
Periodontitis
Parathyroid hormone administration may modulate periodontal tissue levels of interleukin-6, matrix metalloproteinase-2 and matrix metalloproteinase-9 in experimental periodontitis.
Periodontitis
Periodontal Condition and Immunological Aspects of Individuals Hospitalized in the Intensive Care Unit.
Periodontitis
Periodontitis and Endothelial Dysfunction: Periodontal Clinical Parameters and Levels of Salivary Markers Interleukin-1?, Tumor Necrosis Factor-?, Matrix Metalloproteinase-2, Tissue Inhibitor of Metalloproteinases-2 Complex, and Nitric Oxide.
Periodontitis
Proteolytic enzymes as indicators of periodontal health in gingival crevicular fluid of patients with Sjögren's syndrome.
Periodontitis
The role of extracellular matrix metalloproteinase inducer glycosylation in regulating matrix metalloproteinases in periodontitis.
Periodontitis
[Expression of MMP-2 and MMP-3 in periodontal tissues of rat periodontitis model]
Periodontitis
[Impacts of atovastatin and tinidazole on cardiac muscle inflammation factors of tumor necrosis factor-?, interleukin-1 and metalloproteinase-2 of experimental rabbits with atherosclerosis and periodontitis].
Periodontitis
[Protective effect of baicalin on experimental periodontitis in rats and its possible mechanisms]
Peripheral Arterial Disease
Inflammatory biomarkers, vascular procedures of lower limbs, and wound healing.
Peripheral Arterial Disease
Is cardiovascular disease in patients with diabetes associated with serum levels of MMP-2, LOX, and the elastin degradation products ELM and ELM-2?
Peripheral Arterial Disease
Plasma levels and zymographic activities of matrix metalloproteinases 2 and 9 in type II diabetics with peripheral arterial disease.
Peripheral Arterial Disease
Protease-resistant stromal cell-derived factor-1 for the treatment of experimental peripheral artery disease.
Peripheral Nerve Injuries
Role of Matrix Metalloproteinases and Therapeutic Benefits of Their Inhibition in Spinal Cord Injury.
Peritoneal Fibrosis
A case of encapsulating peritoneal sclerosis at the clinical early stage with high concentration of matrix metalloproteinase-2 in peritoneal effluent.
Peritoneal Fibrosis
Abatacept as a therapeutic option in the treatment of encapsulated peritoneal sclerosis: an experimental rat model.
Peritoneal Fibrosis
CAN EFFLUENT MATRIX METALLOPROTEINASE 2 AND PLASMINOGEN ACTIVATOR INHIBITOR 1 BE USED AS BIOMARKERS OF PERITONEAL MEMBRANE ALTERATIONS IN PERITONEAL DIALYSIS PATIENTS?
Peritoneal Fibrosis
Genetic or pharmacologic blockade of enhancer of zeste homolog 2 inhibits the progression of peritoneal fibrosis.
Peritoneal Fibrosis
Inhibitory effects of matrix metalloproteinase inhibitor ONO-4817 on morphological alterations in chlorhexidine gluconate-induced peritoneal sclerosis rats.
Peritoneal Fibrosis
Peritoneal Effluent MMP-2 and PAI-1 in Encapsulating Peritoneal Sclerosis.
Peritoneal Fibrosis
Pioglitazone reduces peritoneal fibrosis via inhibition of TGF-?, MMP-2, and MMP-9 in a model of encapsulating peritoneal sclerosis.
Peritoneal Fibrosis
The effects of interferon alpha2b on chemically-induced peritoneal fibrosis and on peritoneal tissue MMP-2 and TIMP-2 levels in rats.
Peritoneal Fibrosis
The effects of low-dose erythropoiesis-stimulating agents on peritoneal fibrosis induced by chemical peritonitis and on peritoneal tissue MMP-2 and TIMP-2 Levels in rats.
Peritoneal Fibrosis
The potential of matrix metalloproteinase-2 as a marker of peritoneal injury, increased solute transport, or progression to encapsulating peritoneal sclerosis during peritoneal dialysis--a multicentre study in Japan.
Peritoneal Neoplasms
DJ-1 is involved in the peritoneal metastasis of gastric cancer through activation of the Akt signaling pathway.
Peritonitis
Alterations in proteoglycan components and histopathology of the peritoneum in uraemic and peritoneal dialysis (PD) patients.
Peritonitis
Gelatinase B/matrix metalloproteinase-9 contributes to cellular infiltration in a murine model of zymosan peritonitis.
Peritonitis
Gelatinase B/MMP-9 as an inflammatory marker enzyme in mouse zymosan peritonitis: comparison of phase-specific and cell-specific production by mast cells, macrophages and neutrophils.
Peritonitis
HIGHER DIALYSATE MATRIX METALLOPROTEINASE-2 LEVELS ARE ASSOCIATED WITH PERITONEAL MEMBRANE DYSFUNCTION.
Peritonitis
IS256 abolishes gelatinase activity and biofilm formation in a mutant of the nosocomial pathogen Enterococcus faecalis V583.
Peritonitis
Neutrophil emigration in the lungs, peritoneum, and skin does not require gelatinase B.
Peritonitis
Peritonitis increases MMP-9 activity in peritoneal effluent from CAPD patients.
Peritonitis
Prospective evaluation of virulence factors of enterococci isolated from patients with peritonitis: impact on outcome.
Peritonitis
Resolvin D3 multi-level proresolving actions are host protective during infection.
Peritonitis
The effects of low-dose erythropoiesis-stimulating agents on peritoneal fibrosis induced by chemical peritonitis and on peritoneal tissue MMP-2 and TIMP-2 Levels in rats.
Peritonitis
The potential of matrix metalloproteinase-2 as a marker of peritoneal injury, increased solute transport, or progression to encapsulating peritoneal sclerosis during peritoneal dialysis--a multicentre study in Japan.
Phyllodes Tumor
Expression of gelatinase A and TIMP-2 mRNAs in desmoplastic fibroblasts in both mammary carcinomas and basal cell carcinomas of the skin.
Pituitary ACTH Hypersecretion
Expression of serine proteases and metalloproteinases in human pituitary adenomas and anterior pituitary lobe tissue.
Pituitary Neoplasms
CD147 expression in pituitary adenomas and its significance for clinical outcome.
Pituitary Neoplasms
Different patterns of gelatinolytic activity in pituitary macro- and microadenomas.
Pituitary Neoplasms
Enhancement of pituitary adenoma cell invasion and adhesion is mediated by discoidin domain receptor-1.
Pituitary Neoplasms
Expression of serine proteases and metalloproteinases in human pituitary adenomas and anterior pituitary lobe tissue.
Pituitary Neoplasms
High levels of matrix metalloproteinases regulate proliferation and hormone secretion in pituitary cells.
Pituitary Neoplasms
Matrix metalloproteinase 2 and 9 expression correlated with cavernous sinus invasion of pituitary adenomas.
Pituitary Neoplasms
Matrix metalloproteinase-2 expression correlates with cavernous sinus invasion in pituitary adenomas.
Pituitary Neoplasms
Matrix metalloproteinase-9 and -2 and tissue inhibitor of matrix metalloproteinase-2 in invasive pituitary adenomas: A systematic review and meta-analysis of case-control trials.
Pituitary Neoplasms
Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases in Pituitary Adenomas: Possible Markers of Neuroendocrine Cells.
Pituitary Neoplasms
Regulation of angiogenesis and invasion by human Pituitary tumor transforming gene (PTTG) through increased expression and secretion of matrix metalloproteinase-2 (MMP-2).
Pituitary Neoplasms
Type IV collagenase activity and cavernous sinus invasion in human pituitary adenomas.
Pituitary Neoplasms
Up-regulation of the expressions of MiR-149-5p and MiR-99a-3p in exosome inhibits the progress of pituitary adenomas.
Pituitary Neoplasms
[Role of matrix metalloproteinases-9, 2 and their inhibitor-TIMP-1, 2 in invasive pituitary adenomas biological behavior]
Placenta Accreta
Possible Role of TGF-?1, MMP-2, E-CAD, ?-Catenin and Antioxidants in Pathogenesis of Placenta Accreta.
Placenta Accreta
[Involvement of matrix metalloproteinase-2, -9, and tissue inhibitors of metalloproteinase-1, 2 in occurrence of the accrete placenta]
Placenta Previa
Placenta previa may acquire invasive nature by factors associated with epithelial-mesenchymal transition and matrix metalloproteinases.
Placenta, Retained
Activity of 72-kDa and 92-kDa matrix metalloproteinases in placental tissues of cows with and without retained fetal membranes.
Plasmacytoma
Bone marrow angiogenesis and plasma cell angiogenic and invasive potential in patients with active multiple myeloma.
Pleural Effusion
Gelatinolytic activities (matrix metalloproteinase-2 and -9) and soluble extracellular domain of Her-2/neu in pleural effusions.
Pleural Effusion
Matrix metalloproteinase levels in the differentiation of parapneumonic pleural effusions.
Pleural Effusion
Matrix metalloproteinase-2 and matrix metalloproteinase-9 type IV collagenases in serum of patients with pleural effusions.
Pleural Effusion
Matrix metalloproteinases 2 and 9 increase permeability of sheep pleura in vitro.
Pleural Effusion
Occurrence of matrix metalloproteinases and tissue inhibitors of metalloproteinases in tuberculous pleuritis.
Pleural Effusion
Pleural injury and pleurisy-induced progelatinase B/proMMP-9 is associated with markers of neutrophil degranulation.
Pleural Effusion
[Matrix metalloproteinases and their inhibitors in lung cancer with malignant pleural effusion]
Pleurisy
Occurrence of matrix metalloproteinases and tissue inhibitors of metalloproteinases in tuberculous pleuritis.
Pleurisy
Pleural injury and pleurisy-induced progelatinase B/proMMP-9 is associated with markers of neutrophil degranulation.
Pleurisy
Potential role of matrix metalloproteinase-2,-9 and tissue inhibitors of metalloproteinase-1,-2 in exudative pleural effusions.
Pneumoconiosis
Serum concentrations of Krebs von den Lungen-6, surfactant protein D, and matrix metalloproteinase-2 as diagnostic biomarkers in patients with asbestosis and silicosis: a case-control study.
Pneumonia
Alpha-1-antitrypsin aerosolised augmentation abrogates neutrophil elastase-induced expression of cathepsin B and matrix metalloprotease 2 in vivo and in vitro.
Pneumonia
Early and late pulmonary effects of nebulized LPS in mice: An acute lung injury model.
Pneumonia
Elevated serum matrix metalloproteinase-2 and -9 and their correlations with severity of disease in patients with community-acquired pneumonia.
Pneumonia
Iguratimod decreases bleomycin-induced pulmonary fibrosis in association with inhibition of TNF-? in mice.
Pneumonia
Impact of Time on Fluid Resuscitation with Hypertonic Saline (NaCl 7.5%) in Rats with LPS-Induced Acute Lung Injury.
Pneumonia
Increased production of matrix metalloproteinase-2 in alveolar macrophages and regulation by interleukin-10 in patients with acute pulmonary sarcoidosis.
Pneumonia
MMP-9 as a marker of inflammation in tracheal epithelial lining fluid (TELF) and in bronchoalveolar fluid (BALF) of COPD horses.
Pneumonia
Overexpression of Tumor Necrosis Factor-? in the Lungs Alters Immune Response, Matrix Remodeling, and Repair and Maintenance Pathways.
Pneumonia
Pathogenic role of matrix metalloproteases and their inhibitors in asthma and chronic obstructive pulmonary disease and therapeutic relevance of matrix metalloproteases inhibitors.
Pneumonia
Transforming growth factor-?1 suppresses the up-regulation of matrix metalloproteinase-2 by lung fibroblasts in response to tumor necrosis factor-?.
Pneumonia, Bacterial
[Study on inflammatory response and alteration of biochemical components in BALF from Pneumocystis carinii pneumonia]
Pneumoperitoneum
Effect of CO2 pneumoperitoneum on the proliferation of human ovarian cancer cell line SKOV-3 and the expression of NM23-H1 and MMP-2.
Pneumothorax
Association of MMP-2 and MMP-9 expression with recurrences in primary spontaneous pneumothorax.
Pneumothorax
Correlation of matrix metalloproteinase-2 and -9 expression with recurrences in primary spontaneous pneumothorax patients.
Polycystic Kidney Diseases
Matrix metalloproteinase-2 in a murine model of infantile-type polycystic kidney disease.
Polycystic Kidney Diseases
Matrix metalloproteinases synthesized in autosomal dominant polycystic kidney disease play a role in development of a concurrent abdominal aortic aneurysm.
Polycystic Kidney Diseases
Tubular gelatinase A (MMP-2) and its tissue inhibitors in polycystic kidney disease in the Han:SPRD rat.
Polycystic Kidney, Autosomal Dominant
Angiogenesis in autosomal-dominant polycystic kidney disease.
Polycystic Kidney, Autosomal Dominant
Dissection of Iliac Artery in a Patient With Autosomal Dominant Polycystic Kidney Disease: A Case Report.
Polycystic Kidney, Autosomal Dominant
Matrix metalloproteinases synthesized in autosomal dominant polycystic kidney disease play a role in development of a concurrent abdominal aortic aneurysm.
Polycystic Kidney, Autosomal Dominant
Sirolimus ameliorates the enhanced expression of metalloproteinases in a rat model of autosomal dominant polycystic kidney disease.
Polycystic Ovary Syndrome
Elevated serum levels of matrix metalloproteinase-2 in women with polycystic ovarian syndrome.
Polycystic Ovary Syndrome
Increased circulating levels of matrix metalloproteinase-2 and -9 in women with the polycystic ovary syndrome.
Polycystic Ovary Syndrome
Metformin treatment alleviates polycystic ovary syndrome by decreasing the expression of MMP-2 and MMP-9 via H19/miR-29b-3p and AKT/mTOR/autophagy signaling pathways.
Polycystic Ovary Syndrome
Oral contraceptive containing chlormadinone acetate and ethinylestradiol reduces plasma concentrations of matrix metalloproteinase-2 in women with polycystic ovary syndrome.
Polycystic Ovary Syndrome
Significance of matrix metalloproteinases in the pathophysiology of the ovary and uterus.
Polycythemia Vera
Importance of plasma matrix metalloproteinases (MMP) and tissue inhibitors of metalloproteinase (TIMP) in development of fibrosis in agnogenic myeloid metaplasia.
Polymyositis
Expression of matrix metalloproteinases in the muscle of patients with inflammatory myopathies.
Polyneuropathies
Expression pattern of matrix metalloproteinases-2 and -9 and their tissue inhibitors in patients with chronic inflammatory demyelinating polyneuropathy.
Polyneuropathies
Matrix metalloproteinase-2 is involved in myelination of dorsal root ganglia neurons.
Polyradiculoneuropathy, Chronic Inflammatory Demyelinating
Expression pattern of matrix metalloproteinases-2 and -9 and their tissue inhibitors in patients with chronic inflammatory demyelinating polyneuropathy.
Polyradiculoneuropathy, Chronic Inflammatory Demyelinating
Matrix metalloproteinase upregulation in chronic inflammatory demyelinating polyneuropathy and nonsystemic vasculitic neuropathy.
Porphyria Cutanea Tarda
Photosensitization of uroporphyrin augments the ultraviolet A-induced synthesis of matrix metalloproteinases in human dermal fibroblasts.
Porphyrias
Photosensitization of uroporphyrin augments the ultraviolet A-induced synthesis of matrix metalloproteinases in human dermal fibroblasts.
Pouchitis
Comparable expression of matrix metalloproteinases 1 and 2 in pouchitis and ulcerative colitis.
Pre-Eclampsia
Acute actions and novel targets of matrix metalloproteinases in the heart and vasculature.
Pre-Eclampsia
Altered Maternal Serum Matrix Metalloproteinases MMP-2, MMP-3, MMP-9, and MMP-13 in Severe Early- and Late-Onset Preeclampsia.
Pre-Eclampsia
AP-2? suppresses invasion in BeWo cells by repression of matrix metalloproteinase-2 and -9 and up-regulation of E-cadherin.
Pre-Eclampsia
Association between matrix metalloproteinase (MMP)-2 polymorphisms and MMP-2 levels in hypertensive disorders of pregnancy.
Pre-Eclampsia
CXCR2 is decreased in preeclamptic placentas and promotes human trophoblast invasion through the Akt signaling pathway.
Pre-Eclampsia
Dysregulated expression of matrix metalloproteinases and their inhibitors may participate in the pathogenesis of pre-eclampsia and fetal growth restriction.
Pre-Eclampsia
Effects of Matrix Metalloproteinase (MMP)-2 Polymorphisms on Responsiveness to Antihypertensive Therapy of Women with Hypertensive Disorders of Pregnancy.
Pre-Eclampsia
Elevated expression of KiSS-1 in placenta of preeclampsia and its effect on trophoblast.
Pre-Eclampsia
Evaluation of metalloproteinases 2 and 9 and their inhibitors in physiologic and pre-eclamptic pregnancy.
Pre-Eclampsia
Gelatinase matrix metalloproteinase (MMP)-2 and MMP-9 of the umbilical cord blood in preeclampsia.
Pre-Eclampsia
Gene expression analysis of MMPs in women with preeclampsia using cell-free fetal RNA in maternal plasma.
Pre-Eclampsia
Increased urinary levels of podocyte glycoproteins, matrix metallopeptidases, inflammatory cytokines, and kidney injury biomarkers in women with preeclampsia.
Pre-Eclampsia
Matrix metalloproteinase enhances big-endothelin-1 constriction in mesenteric vessels of pregnant rats with reduced uterine blood flow.
Pre-Eclampsia
Matrix metalloproteinase multiplex screening identifies increased MMP-2 urine concentrations in women predicted to develop preeclampsia.
Pre-Eclampsia
Matrix metalloproteinase-2 C-735T and its interaction with matrix metalloproteinase-7 A-181G polymorphism are associated with the risk of preeclampsia: influence on total antioxidant capacity and blood pressure.
Pre-Eclampsia
Matrix metalloproteinase-2 is elevated in midtrimester amniotic fluid prior to the development of preeclampsia.
Pre-Eclampsia
Matrix metalloproteinase-2 is elevated in the plasma of women with preeclampsia.
Pre-Eclampsia
Matrix metalloproteinases MMP-2 and MMP-9 as markers for the prediction of preeclampsia in the first trimester.
Pre-Eclampsia
Matrix Metalloproteinases MMP-2 and MMP-9 Occupy a New Role in Severe Preeclampsia.
Pre-Eclampsia
Matrix metalloproteinases-2 (MMP-2) and matrix metalloproteinases -9 (MMP-9) are differentially expressed in different regions of normal and preeclampsia placentae.
Pre-Eclampsia
Midregional pro-adrenomedullin and matrix metalloproteinase-2 levels in intrauterine growth restriction and small gestational age pregnancies: biochemical diagnostic difference.
Pre-Eclampsia
MMP-2 and MMP-9 Polymorphisms and Preeclampsia Risk in Tunisian Arabs: A Case-Control Study.
Pre-Eclampsia
MMP-2 levels are elevated in the plasma of women who subsequently develop preeclampsia.
Pre-Eclampsia
Ratio of matrix metalloproteinase-2 to -9 is a more accurate predictive biomarker in women with suspected pre-eclampsia.
Pre-Eclampsia
Relationship between 3D Power Doppler Ultrasound and Serum MMP-2 and Ang-2 Levels in Pregnant Women with Preeclampsia.
Pre-Eclampsia
Role of Gelatinases MMP-2 and MMP-9 in Healthy and Complicated Pregnancy and Their Future Potential as Preeclampsia Biomarkers.
Pre-Eclampsia
The activity of collagen-degrading enzymes of Wharton's jelly in EPH gestosis (pre-eclampsia).
Pre-Eclampsia
The effect of serum from women with preeclampsia on JAR (trophoblast-like) cell line.
Pre-Eclampsia
The effects of preeclampsia and oxygen environment on endothelial release of matrix metalloproteinase-2.
Pre-Eclampsia
Up-regulation of miR-517-5p inhibits ERK/MMP-2 pathway: potential role in preeclampsia.
Pre-Eclampsia
Vascular endothelial growth factor induces endothelin-1 production via matrix metalloproteinase-2 rather than endothelin-converting enzyme-1.
Pre-Eclampsia
[Differences between the expression of matrix metalloproteinase-2, 9 in preeclampsia and normal placental tissues]
Pre-Eclampsia
[Effect of microRNA-106b on the invasion and proliferation of trophoblasts through targeting MMP-2].
Pre-Eclampsia
[Expression and significance of SATB1 and wnt/?-catenin signaling molecule in the placenta of preeclampsia].
Pre-Eclampsia
[Expression of trophoblast invasion related genes mRNA and protein in human placenta in preeclampsia]
Pre-Eclampsia
[Homocysteine decreases the invasion in cultured human trophoblasts: relationship between homocysteine and matrix metalloproteinase-2, -9 expression]
Pre-Eclampsia
[Inhibitory effects of soluble endoglin on invasive ability of cultured cytotrophoblasts of first trimester of pregnancy.]
Pre-Eclampsia
[The markers of inflammation reaction and dysfunction of endothelium in pregnant women with hypertension disorders of various genesis].
Precancerous Conditions
Expression of matrix metalloproteinase-1, -2 and -3 in squamous cell carcinoma and actinic keratosis.
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma
Spontaneous and cytokine-evoked production of matrix metalloproteinases by bone marrow and peripheral blood pre-B cells in childhood acute lymphoblastic leukaemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
DNA methylation-mediated silencing of microRNA-204 enhances T cell acute lymphoblastic leukemia by up-regulating MMP-2 and MMP-9 via NF-?B.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Proteolytic activity of human lymphoid tumor cells. Correlation with tumor progression.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Secretion of MMP-2 and MMP-9 induced by VEGF autocrine loop correlates with clinical features in childhood acute lymphoblastic leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
The Relationship Between MMP-2 -1306C>T and MMP-9 -1562C>T Polymorphisms and the Risk and Prognosis of T-Cell Acute Lymphoblastic Leukemia in a Chinese Population: A Case-Control Study.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
[Expression and clinical significance of MMP-2 and MMP-9 in B acute lymphoblastic leukemia].
Precursor Cell Lymphoblastic Leukemia-Lymphoma
[Plasma matrix metalloproteinases MMP-2 and MMP-9 and tissue inhibitors TIMP-1 and TIMP-2 in children treated for acute lymphoblastic leukemia]
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
DNA methylation-mediated silencing of microRNA-204 enhances T cell acute lymphoblastic leukemia by up-regulating MMP-2 and MMP-9 via NF-?B.
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
The Relationship Between MMP-2 -1306C>T and MMP-9 -1562C>T Polymorphisms and the Risk and Prognosis of T-Cell Acute Lymphoblastic Leukemia in a Chinese Population: A Case-Control Study.
Pregnancy Complications
Programmed cell death (apoptosis) as a possible pathway to metalloproteinase activation and fetal membrane degradation in premature rupture of membranes.
Pregnancy, Ectopic
Co-ordinated expression of MMP-2 and its putative activator, MT1-MMP, in human placentation.
Pregnancy, Ectopic
Immunohistochemical expression of matrix metalloproteinases 1 and 2 (MMP-1 and MMP-2) and tissue inhibitor of metalloproteinase 2 (TIMP-2) in ruptured and non-ruptured tubal ectopic pregnancies.
Pregnancy, High-Risk
Activities of matrix metalloproteinase-2 and -9 in amniotic fluid at parturition in mares with normal and high-risk pregnancy.
Pregnancy, Tubal
Co-ordinated expression of MMP-2 and its putative activator, MT1-MMP, in human placentation.
Pregnancy, Tubal
Dynamic expression of matrix metalloproteinases (MMP-2, -9 and -14) and the tissue inhibitors of MMPs (TIMP-1, -2 and -3) at the implantation site during tubal pregnancy.
Pregnancy, Tubal
Immunohistochemical expression of matrix metalloproteinases 1 and 2 (MMP-1 and MMP-2) and tissue inhibitor of metalloproteinase 2 (TIMP-2) in ruptured and non-ruptured tubal ectopic pregnancies.
Premature Birth
Maternal infection with Schistosoma japonicum induces a profibrotic response in neonates.
Premature Birth
Relationship between metalloproteinase-2 and -9 levels in plasma and vaginal secretion with preterm birth.
Pressure Ulcer
Wound fluids from human pressure ulcers contain elevated matrix metalloproteinase levels and activity compared to surgical wound fluids.
Pressure Ulcer
[Expression and significance of tumor necrosis factor alpha, matrix metalloproteinase 2 and collagen in skin tissue of pressure ulcer of rats].
Primary Myelofibrosis
Elevated plasma levels of TIMP-1 correlate with plasma suPAR/uPA in patients with chronic myeloproliferative disorders.
Primary Ovarian Insufficiency
Association study of five functional polymorphisms in matrix metalloproteinase-2, -3, and -9 genes with risk of primary ovarian insufficiency in Korean women.
Prolactinoma
Expression of serine proteases and metalloproteinases in human pituitary adenomas and anterior pituitary lobe tissue.
Prolactinoma
Matrix metalloproteinase-9 and tissue inhibitor of matrix metalloproteinase-2: Prognostic biological markers in invasive prolactinomas.
Prostatic Diseases
Differential expression of Low density lipoprotein Receptor-related Protein 1 (LRP-1) and matrix metalloproteinase-9 (MMP-9) in prostate gland: From normal to malignant lesions.
Prostatic Hyperplasia
Activation of the osteopontin/matrix metalloproteinase-9 pathway correlates with prostate cancer progression.
Prostatic Hyperplasia
Association between MMP-2 expression and prostate cancer: A meta-analysis.
Prostatic Hyperplasia
CD147, MMP-1, MMP-2 and MMP-9 Protein Expression as Significant Prognostic Factors in Human Prostate Cancer.
Prostatic Hyperplasia
Differential expression of Low density lipoprotein Receptor-related Protein 1 (LRP-1) and matrix metalloproteinase-9 (MMP-9) in prostate gland: From normal to malignant lesions.
Prostatic Hyperplasia
Immunohistochemical analysis of type IV collagenase expression in prostatic hyperplasia and adenocarcinoma.
Prostatic Hyperplasia
Immunohistochemical studies of the expression of matrix metalloproteinase-2 and metalloproteinase-9 in human prostate cancer.
Prostatic Hyperplasia
In situ hybridization studies of metalloproteinases 2 and 9 and TIMP-1 and TIMP-2 expression in human prostate cancer.
Prostatic Hyperplasia
Increased matrix metalloproteinase-9 secretion in short-term tissue cultures of prostatic tumor cells.
Prostatic Hyperplasia
MMP-2 detective silicon nanowire biosensor using enzymatic cleavage reaction.
Prostatic Hyperplasia
Plasminogen activator activities in short-term tissue cultures of benign prostatic hyperplasia and prostatic carcinoma.
Prostatic Hyperplasia
Type IV collagenase (M(r) 72,000) expression in human prostate: benign and malignant tissue.
Prostatic Intraepithelial Neoplasia
Differential expression of Low density lipoprotein Receptor-related Protein 1 (LRP-1) and matrix metalloproteinase-9 (MMP-9) in prostate gland: From normal to malignant lesions.
Prostatic Intraepithelial Neoplasia
Hyperglycemia and T Cell infiltration are associated with stromal and epithelial prostatic hyperplasia in the nonobese diabetic mouse.
Prostatic Intraepithelial Neoplasia
Immunohistochemical evaluation of type IV collagenase (72-kd metalloproteinase) in prostatic intraepithelial neoplasia.
Prostatic Intraepithelial Neoplasia
Increased expression of the 72-kd type IV collagenase in prostatic adenocarcinoma. Demonstration by immunohistochemistry and in situ hybridization.
Prostatic Intraepithelial Neoplasia
Membrane type 1-matrix metalloproteinase (MT1-MMP) and MMP-2 immunolocalization in human prostate: change in cellular localization associated with high-grade prostatic intraepithelial neoplasia.
Prostatic Neoplasms
(±)Equol inhibits invasion in prostate cancer DU145 cells possibly via down-regulation of matrix metalloproteinase-9, matrix metalloproteinase-2 and urokinase-type plasminogen activator by antioxidant activity.
Prostatic Neoplasms
A short-hairpin RNA targeting osteopontin downregulates MMP-2 and MMP-9 expressions in prostate cancer PC-3 cells.
Prostatic Neoplasms
Activation of the osteopontin/matrix metalloproteinase-9 pathway correlates with prostate cancer progression.
Prostatic Neoplasms
Activator protein 2alpha transcription factor expression is associated with luminal differentiation and is lost in prostate cancer.
Prostatic Neoplasms
Activities and polymorphisms of MMP-2 and MMP-9, smoking, diabetes and risk of prostate cancer.
Prostatic Neoplasms
ADAM17 targets MMP-2 and MMP-9 via EGFR-MEK-ERK pathway activation to promote prostate cancer cell invasion.
Prostatic Neoplasms
Adenovirus-mediated expression of TIMP-1 and TIMP-2 in bone inhibits osteolytic degradation by human prostate cancer.
Prostatic Neoplasms
Adipocyte-derived monocyte chemotactic protein-1 (MCP-1) promotes prostate cancer progression through the induction of MMP-2 activity.
Prostatic Neoplasms
Amplification of MMP-2 and MMP-9 production by prostate cancer cell lines via activation of protease-activated receptors.
Prostatic Neoplasms
Androgen stimulates matrix metalloproteinase-2 expression in human prostate cancer.
Prostatic Neoplasms
Assessment of indirect hemagglutination and zymography procedures in evaluation of gelatinase a in patients with benign and malignant prostate hyperplasia.
Prostatic Neoplasms
Association between MMP-2 expression and prostate cancer: A meta-analysis.
Prostatic Neoplasms
Association of Promoter Polymorphisms in MMP 2 and TIMP2 with Prostate Cancer Susceptibility in North India.
Prostatic Neoplasms
Autocrine factors, type IV collagenase secretion and prostatic cancer cell invasion.
Prostatic Neoplasms
Blockade of the type I IGF receptor expression in human prostate cancer cells inhibits proliferation and invasion, up-regulates IGF binding protein-3, and suppresses MMP-2 expression.
Prostatic Neoplasms
Bruton's Tyrosine Kinase (BTK) Inhibitor (Ibrutinib)?-Suppressed Migration and Invasion of Prostate Cancer.
Prostatic Neoplasms
CD147, MMP-1, MMP-2 and MMP-9 Protein Expression as Significant Prognostic Factors in Human Prostate Cancer.
Prostatic Neoplasms
Characterization of protease expression in human prostate-cancer cell-lines.
Prostatic Neoplasms
Chemokine CXCL12 and its receptor CXCR4 expression are associated with perineural invasion of prostate cancer.
Prostatic Neoplasms
Circulating levels of VCAM and MMP-2 may help identify patients with more aggressive prostate cancer.
Prostatic Neoplasms
Comparative study of stromal metalloproteases expression in patients with benign hyperplasia and prostate cancer.
Prostatic Neoplasms
Concise syntheses of the abyssinones and discovery of new inhibitors of prostate cancer and MMP-2 expression.
Prostatic Neoplasms
Concomitant reduction of matrix metalloproteinase-2 secretion and intracellular reactive oxygen species following anti-sense inhibition of telomerase activity in PC-3 prostate carcinoma cells.
Prostatic Neoplasms
Correlation of metastasis-related gene expression with metastatic potential in human prostate carcinoma cells implanted in nude mice using an in situ messenger RNA hybridization technique.
Prostatic Neoplasms
Determination of gelatinase A using a modified indirect hemagglutination assay in human prostate cancer screening and assessment of its correlation with prostate-specific antigen parameters.
Prostatic Neoplasms
Different mRNA and protein expression of matrix metalloproteinases 2 and 9 and tissue inhibitor of metalloproteinases 1 in benign and malignant prostate tissue.
Prostatic Neoplasms
Differential expression of Low density lipoprotein Receptor-related Protein 1 (LRP-1) and matrix metalloproteinase-9 (MMP-9) in prostate gland: From normal to malignant lesions.
Prostatic Neoplasms
Differential expression of matrix metalloproteinase-2 expression in disseminated tumor cells and micrometastasis in bone marrow of patients with nonmetastatic and metastatic prostate cancer: theoretical considerations and clinical implications-an immunocytochemical study.
Prostatic Neoplasms
Dual androgen-response elements mediate androgen regulation of MMP-2 expression in prostate cancer cells.
Prostatic Neoplasms
E2F5 promotes prostate cancer cell migration and invasion through regulation of TFPI2, MMP-2 and MMP-9.
Prostatic Neoplasms
Effect of 17beta-estradiol on apoptosis, IGF system components and gelatinases A and B in prostate cancer cells (PC-3).
Prostatic Neoplasms
Effect of androgen blockade on HER-2 and matrix metalloproteinase-2 expression on bone marrow micrometastasis and stromal cells in men with prostate cancer.
Prostatic Neoplasms
Enhancing Accumulation and Penetration of HPMA Copolymer-Doxorubicin Conjugates in 2D and 3D Prostate Cancer Cells via iRGD Conjugation with an MMP-2 Cleavable Spacer.
Prostatic Neoplasms
Estrogens promote invasion of prostate cancer cells in a paracrine manner through up-regulation of matrix metalloproteinase 2 in prostatic stromal cells.
Prostatic Neoplasms
Evidence for increased activated metalloproteinase 2 (MMP-2a) expression associated with human prostate cancer progression.
Prostatic Neoplasms
Expression of matrix metalloproteinase-2 and prostate-specific antigen in localized and metastatic prostate cancer.
Prostatic Neoplasms
Expression of matrix metalloproteinase-26 in multiple human cancer tissues and smooth muscle cells.
Prostatic Neoplasms
Expression of matrix metalloproteinases (MMP-2 and -9) and their inhibitors (TIMP-1 and -2) in prostate cancer tissue.
Prostatic Neoplasms
Filamin C, a dysregulated protein in cancer revealed by label-free quantitative proteomic analyses of human gastric cancer cells.
Prostatic Neoplasms
Gallic acid suppresses the migration and invasion of PC-3 human prostate cancer cells via inhibition of matrix metalloproteinase-2 and -9 signaling pathways.
Prostatic Neoplasms
Genistein inhibits p38 map kinase activation, matrix metalloproteinase type 2, and cell invasion in human prostate epithelial cells.
Prostatic Neoplasms
Genistein treatment duration effects biomarkers of cell motility in human prostate.
Prostatic Neoplasms
Genistein-selenium combination induces growth arrest in prostate cancer cells.
Prostatic Neoplasms
GPNMB/OA protein increases the invasiveness of human metastatic prostate cancer cell lines DU145 and PC3 through MMP-2 and MMP-9 activity.
Prostatic Neoplasms
High matrix metalloproteinase-to-E-cadherin ratio measured by bicolor fluorescent in situ hybridization is associated with lymphangiogenesis and lymph node metastasis in prostate cancer.
Prostatic Neoplasms
High mobility group protein HMGI(Y) enhances tumor cell growth, invasion, and matrix metalloproteinase-2 expression in prostate cancer cells.
Prostatic Neoplasms
Human chorionic gonadotropin ? induces migration and invasion via activating ERK1/2 and MMP-2 in human prostate cancer DU145 cells.
Prostatic Neoplasms
IL-10 blocks collagen IV invasion by "invasion stimulating factor" activated PC-3 ML cells: upregulation of TIMP-1 expression.
Prostatic Neoplasms
Immunohistochemical studies of activated matrix metalloproteinase-2 (MMP-2a)expression in human prostate cancer.
Prostatic Neoplasms
Immunohistochemical studies of the expression of matrix metalloproteinase-2 and metalloproteinase-9 in human prostate cancer.
Prostatic Neoplasms
In situ hybridization studies of metalloproteinases 2 and 9 and TIMP-1 and TIMP-2 expression in human prostate cancer.
Prostatic Neoplasms
Influence of genistein isoflavone on matrix metalloproteinase-2 expression in prostate cancer cells.
Prostatic Neoplasms
Inhibition of human prostate cancer growth, osteolysis and angiogenesis in a bone metastasis model by a novel mechanism-based selective gelatinase inhibitor.
Prostatic Neoplasms
Inhibition of tumorigenic potential and prostate-specific antigen expression in LNCaP human prostate cancer cell line by 13-cis-retinoic acid.
Prostatic Neoplasms
Integrin ?v?6 Promotes an Osteolytic Program in Cancer Cells by Upregulating MMP2.
Prostatic Neoplasms
Kindlin-2 promotes invasiveness of prostate cancer cells via NF-?B-dependent upregulation of matrix metalloproteinases.
Prostatic Neoplasms
Limited processing of pro-matrix metalloprotease-2 (gelatinase A) overexpressed by transfection in PC-3 human prostate tumor cells: association with restricted cell surface localization of membrane-type matrix metalloproteinase-1.
Prostatic Neoplasms
LOX-1 activation by oxLDL triggers an epithelial mesenchymal transition and promotes tumorigenic potential in prostate cancer cells.
Prostatic Neoplasms
Luteolin inhibits human prostate tumor growth by suppressing vascular endothelial growth factor receptor 2-mediated angiogenesis.
Prostatic Neoplasms
MAPKAPK2 and HSP27 are downstream effectors of p38 MAP kinase-mediated matrix metalloproteinase type 2 activation and cell invasion in human prostate cancer.
Prostatic Neoplasms
Matrix metalloproteinase and heparin-stimulated serine proteinase activities in post-prostate massage urine of men with prostate cancer.
Prostatic Neoplasms
Matrix metalloproteinase-2 and -9 in the urine of prostate cancer patients.
Prostatic Neoplasms
Matrix metalloproteinase-2 contributes to increased platelet reactivity in patients with metastatic prostate cancer: a preliminary study.
Prostatic Neoplasms
Matrix metalloproteinase-2 in blood does not indicate the progression of prostate cancer.
Prostatic Neoplasms
Matrix metalloproteinase-2 polymorphism is associated with prognosis in prostate cancer.
Prostatic Neoplasms
Matrix metalloproteinases 2 and 9 immunoexpression in prostate carcinoma at the positive margin of radical prostatectomy specimens.
Prostatic Neoplasms
MEK4 function, genistein treatment, and invasion of human prostate cancer cells.
Prostatic Neoplasms
Membrane type 1-matrix metalloproteinase (MT1-MMP) and MMP-2 immunolocalization in human prostate: change in cellular localization associated with high-grade prostatic intraepithelial neoplasia.
Prostatic Neoplasms
Membrane-type-1 matrix metalloproteinase, matrix metalloproteinase 2, and tissue inhibitor of matrix proteinase 2 in prostate cancer: identification of patients with poor prognosis by immunohistochemistry.
Prostatic Neoplasms
miR-29b enhances prostate cancer cell invasion independently of MMP-2 expression.
Prostatic Neoplasms
MMP-2 detective silicon nanowire biosensor using enzymatic cleavage reaction.
Prostatic Neoplasms
MMP-2, MMP-9 and activin A blood levels in patients with breast cancer or prostate cancer metastatic to the bone.
Prostatic Neoplasms
Molecular mechanisms of the antimetastatic activity of nuclear clusterin in prostate cancer cells.
Prostatic Neoplasms
Neuropeptides induce Mr 92,000 type IV collagenase (matrix metalloprotease-9) activity in human prostate cancer cell lines.
Prostatic Neoplasms
Novel regulation of type IV collagenase (matrix metalloproteinase-9 and -2) activities by transforming growth factor-beta1 in human prostate cancer cell lines.
Prostatic Neoplasms
Novel roles of androgen receptor, epidermal growth factor receptor, TP53, regulatory RNAs, NF-kappa-B, chromosomal translocations, neutrophil associated gelatinase, and matrix metalloproteinase-9 in prostate cancer and prostate cancer stem cells.
Prostatic Neoplasms
ODAM is a predictor for biomedical recurrence and inhibits the migration and invasion of prostate cancer.
Prostatic Neoplasms
Over-expression of hypoxia-inducible factor-1alpha increases the invasive potency of LNCaP cells in vitro.
Prostatic Neoplasms
Overexpression of short TRPM8 variant ? promotes cell migration and invasion, and decreases starvation-induced apoptosis in prostate cancer LNCaP cells.
Prostatic Neoplasms
P504S expressing circulating prostate cells as a marker for prostate cancer.
Prostatic Neoplasms
PD98059-inhibited invasion of Dunning rat prostate cancer cells involves suppression of motility but not MMP-2 or uPA secretion.
Prostatic Neoplasms
Pinin promotes tumor progression via activating CREB through PI3K/AKT and ERK/MAPK pathway in prostate cancer.
Prostatic Neoplasms
Platelet-derived microparticles promote invasiveness of prostate cancer cells via upregulation of MMP-2 production.
Prostatic Neoplasms
Polymorphisms in MMP-2 and TIMP-2 in Turkish patients with prostate cancer.
Prostatic Neoplasms
Proanthocyanidins from the American Cranberry (Vaccinium macrocarpon) inhibit matrix metalloproteinase-2 and matrix metalloproteinase-9 activity in human prostate cancer cells via alterations in multiple cellular signalling pathways.
Prostatic Neoplasms
Prognostic significance of matrix metalloproteinase 2 and tissue inhibitor of metalloproteinase 2 expression in prostate cancer.
Prostatic Neoplasms
Protein kinase D1 inhibits cell proliferation through matrix metalloproteinase-2 and matrix metalloproteinase-9 secretion in prostate cancer.
Prostatic Neoplasms
Relative expression of type IV collagenase, E-cadherin, and vascular endothelial growth factor/vascular permeability factor in prostatectomy specimens distinguishes organ-confined from pathologically advanced prostate cancers.
Prostatic Neoplasms
Rho-Associated Protein Kinase (ROCK) Promotes Proliferation and Migration of PC-3 and DU145 Prostate Cancer Cells by Targeting LIM Kinase 1 (LIMK1) and Matrix Metalloproteinase-2 (MMP-2).
Prostatic Neoplasms
RNA-based markers in biopsy cores with atypical small acinar proliferation: Predictive effect of T2E fusion positivity and MMP-2 upregulation for a subsequent prostate cancer diagnosis.
Prostatic Neoplasms
Role of RUNX3 in suppressing metastasis and angiogenesis of human prostate cancer.
Prostatic Neoplasms
Roles of matrix metalloproteinases and their natural inhibitors in prostate cancer progression.
Prostatic Neoplasms
Roles of microsomal prostaglandin E synthase-1 in lung metastasis formation in prostate cancer RM9 cells.
Prostatic Neoplasms
Serum matrix metalloproteinase-2 and its density in men with prostate cancer as a new predictor of disease extension.
Prostatic Neoplasms
Significance of MMP-2 expression in prostate cancer: an immunohistochemical study.
Prostatic Neoplasms
Silencing of a novel tumor metastasis suppressor gene LASS2/TMSG1 promotes invasion of prostate cancer cell in vitro through increase of vacuolar ATPase activity.
Prostatic Neoplasms
Silencing of LASS2/TMSG1 enhances invasion and metastasis capacity of prostate cancer cell.
Prostatic Neoplasms
Silibinin inhibits prostate cancer invasion, motility and migration by suppressing vimentin and MMP-2 expression.
Prostatic Neoplasms
SIRT1 enhances matrix metalloproteinase-2 expression and tumor cell invasion in prostate cancer cells.
Prostatic Neoplasms
SKI-606 (Bosutinib) Blocks Prostate Cancer Invasion, Growth, and Metastasis In vitro and In vivo through Regulation of Genes Involved in Cancer Growth and Skeletal Metastasis.
Prostatic Neoplasms
SPAG9 expression is increased in human prostate cancer and promotes cell motility, invasion and angiogenesis in vitro.
Prostatic Neoplasms
Tetraiodothyroacetic acid and transthyretin silencing inhibit pro-metastatic effect of L-thyroxin in anoikis-resistant prostate cancer cells through regulation of MAPK/ERK pathway.
Prostatic Neoplasms
The p75(NTR) metastasis suppressor inhibits urokinase plasminogen activator, matrix metalloproteinase-2 and matrix metalloproteinase-9 in PC-3 prostate cancer cells.
Prostatic Neoplasms
The role of the androgen receptor in prostate cancer-induced platelet aggregation and platelet-induced invasion.
Prostatic Neoplasms
Thrombospondin-2 promotes prostate cancer bone metastasis by the up-regulation of matrix metalloproteinase-2 through down-regulating miR-376c expression.
Prostatic Neoplasms
Tubulin-binding agents down-regulate matrix metalloproteinase-2 and -9 in human hormone-refractory prostate cancer cells - A critical role of Cdk1 in mitotic entry.
Prostatic Neoplasms
Type IV collagenase (M(r) 72,000) expression in human prostate: benign and malignant tissue.
Prostatic Neoplasms
Type IV collagenase (matrix metalloproteinase-2 and -9) in prostate cancer.
Prostatic Neoplasms
Underexpression of MMP-2 and its regulators, TIMP2, MT1-MMP and IL-8, is associated with prostate cancer.
Prostatic Neoplasms
Vasoactive intestinal peptide behaves as a pro-metastatic factor in human prostate cancer cells.
Prostatic Neoplasms
[Effects of FRZB on growth and metastasis of gastric cancer cell line SGC-7901]
Prostatic Neoplasms
[Inhibitory effect of 3-bromopyruvate on the proliferation, migration and invasive ability of prostate cancer PC-3 cells].
Prostatic Neoplasms
[Over-expression of Hypoxia-inducible factor 1alpha increases invasive potency of LNCaP cells in vitro]
Prostatic Neoplasms
[P2Y purinergic receptor activated PI-3K/Akt signaling pathway in regulation of growth and invasion of prostatic cancer]
Prostatic Neoplasms
[Prognostic value of stromal immunolabelling by MMP-2, MT1-MMP and TIMP-2 in clinically localized prostate cancer]
Prostatitis
Differential expression of Low density lipoprotein Receptor-related Protein 1 (LRP-1) and matrix metalloproteinase-9 (MMP-9) in prostate gland: From normal to malignant lesions.
Prostatitis
Matrix metalloproteinases in the pathogenesis of estradiol-induced nonbacterial prostatitis in the lateral prostate lobe of the Wistar rat.
protein-glutamine gamma-glutamyltransferase deficiency
Association between expression of MMP-2 and MMP-9 genes and pathogenesis of intracranial hemorrhage in severe coagulation factor XIII deficiency.
protein-glutamine gamma-glutamyltransferase deficiency
Expression and CpG island methylation pattern of MMP-2 and MMP-9 genes in patients with congenital factor XIII deficiency and intracranial hemorrhage.
Proteinuria
Chronic humoral rejection of human kidney allografts is associated with MMP-2 accumulation in podocytes and its release in the urine.
Proteinuria
Circulating Matrix Metalloproteinase-2 Is an Independent Correlate of Proteinuria in Patients with Chronic Kidney Disease.
Proteinuria
Circulating matrix metalloproteinase-2 is associated with cystatin C level, posttransplant duration, and diabetes mellitus in kidney transplant recipients.
Proteinuria
Delivery of megsin siRNA plasmid reveals therapeutic potential against diabetic nephropathy by down-regulating p27kip1 level.
Proteinuria
Effect of a specific endothelin receptor A antagonist and an angiotensin-converting enzyme inhibitor on glomerular mRNA levels for extracellular matrix components, metalloproteinases (MMP) and a tissue inhibitor of MMP in aminonucleoside nephrosis.
Proteinuria
Increased plasma matrix metalloproteinase-2 (MMP-2), tissue inhibitor of proteinase-1 (TIMP-1), TIMP-2, and urine MMP-2 concentrations correlate with proteinuria in renal transplant recipients.
Proteinuria
Integrin alpha1beta1 regulates matrix metalloproteinases via P38 mitogen-activated protein kinase in mesangial cells: implications for Alport syndrome.
Proteinuria
Loss of diacylglycerol kinase ? causes thrombotic microangiopathy by impairing endothelial VEGFA signaling.
Proteinuria
Overexpression of connective tissue growth factor in podocytes worsens diabetic nephropathy in mice.
Proteinuria
Role of Paricalcitol in Modulating the Immune Response in Patients with Renal Disease.
Proteinuria
The role of matrix metalloproteinases 2 in atherosclerosis of patients with chronic kidney disease in type 2 diabetes.
Proteinuria
Treatment of experimental immune complex glomerulonephritis by sodium alginate.
Proteinuria
Urinary Metalloproteinases-9 and -2 and Their Inhibitors TIMP-1 and TIMP-2 are Markers of Early and Long-Term Graft Function After Renal Transplantation.
Pruritus
Effects of combined Pulsed Dye Laser and Fractional CO2 Laser treatment of burn scars and correlation with plasma levels of collagen type I, MMP-2 and TIMP-1.
Pseudoxanthoma Elasticum
Dermal fibroblasts from pseudoxanthoma elasticum patients have raised MMP-2 degradative potential.
Pseudoxanthoma Elasticum
Elevated circulating levels of matrix metalloproteinases MMP-2 and MMP-9 in pseudoxanthoma elasticum patients.
Psoriasis
Basement membrane alterations in psoriasis are accompanied by epidermal overexpression of MMP-2 and its inhibitor TIMP-2.
Psoriasis
Decreased levels of metalloproteinase-9 and angiogenic factors in skin lesions of patients with psoriatic arthritis after therapy with anti-TNF-alpha.
Psoriasis
Effective Therapy with Anti-TNF-{alpha} in Patients with Psoriatic Arthritis Is Associated with Decreased Levels of Metalloproteinases and Angiogenic Cytokines in the Sera and Skin Lesions.
Psoriasis
Genotype association of C(-735)T polymorphism in matrix metalloproteinase 2 gene with G(8002)A endothelin 1 gene with plaque psoriasis.
Psoriasis
Local antimicrobial, protease and cytokine defense systems in psoriatic skin.
Psoriasis
The Increased Expression of Matrix Metalloproteinase-9 Messenger RNA in the Non-lesional Skin of Patients with Large Plaque Psoriasis Vulgaris.
Psoriasis
Therapy of psoriasis with narrowband ultraviolet-B light influences plasma concentrations of MMP-2 and TIMP-2 in patients.
Psoriasis
VEGF is likely a key factor in the link between inflammation and angiogenesis in psoriasis: results of an immunohistochemical study.
Pterygium
Expression of gelatinase (MMP-2 and MMP-9) in pterygia and pterygium fibroblasts is increased with disease progression and activation of protein kinase C.
Pterygium
Pterygia pathogenesis: corneal invasion by matrix metalloproteinase expressing altered limbal epithelial basal cells.
Puerperal Infection
Protease production by microorganisms associated with reproductive tract infection.
Pulmonary Alveolar Proteinosis
Elevated gelatinase activity in pulmonary alveolar proteinosis: role of macrophage-colony stimulating factor.
Pulmonary Arterial Hypertension
Involvement of matrix metalloproteinase-2 in medial hypertrophy of pulmonary arterioles in broiler chickens with pulmonary arterial hypertension.
Pulmonary Arterial Hypertension
Matrix metalloproteinase 7 in diagnosis and differentiation of pulmonary arterial hypertension.
Pulmonary Arterial Hypertension
MMP-2 and MMP-9 contribute to the angiogenic effect produced by hypoxia/15-HETE in pulmonary endothelial cells.
Pulmonary Atelectasis
Inhibition of matrix metalloproteinases in gerbil cholesteatoma: preliminary findings.
Pulmonary Disease, Chronic Obstructive
Activity of matrix metalloproteinase in airway epithelial cells of COPD patients.
Pulmonary Disease, Chronic Obstructive
AEBP1, a prognostic indicator, promotes colon adenocarcinoma cell growth and metastasis through the NF-?B pathway.
Pulmonary Disease, Chronic Obstructive
An Insight into COPD Morphopathogenesis: Chronic Inflammation, Remodeling, and Antimicrobial Defense.
Pulmonary Disease, Chronic Obstructive
Association of MMP-2 polymorphisms with severe and very severe COPD: a case control study of MMPs-1, 9 and 12 in a European population.
Pulmonary Disease, Chronic Obstructive
Cigarette smoke exposure inhibits extracellular MMP-2 (gelatinase A) activity in human lung fibroblasts.
Pulmonary Disease, Chronic Obstructive
Cigarette smoke stimulates matrix metalloproteinase-2 activity via EGR-1 in human lung fibroblasts.
Pulmonary Disease, Chronic Obstructive
Delay of airway epithelial wound repair in COPD is associated with airflow obstruction severity.
Pulmonary Disease, Chronic Obstructive
Elevated serum matrix metalloprotease (MMP-2) as a candidate biomarker for stable COPD.
Pulmonary Disease, Chronic Obstructive
Enhanced levels of prostaglandin E2 and matrix metalloproteinase-2 correlate with the severity of airflow limitation in stable COPD.
Pulmonary Disease, Chronic Obstructive
Expression of Matrix Metalloproteinase-2, Matrix Metalloproteinase-9, Tissue Inhibitor of Metalloproteinase-1, and Changes in Alveolar Septa in Patients with Chronic Obstructive Pulmonary Disease.
Pulmonary Disease, Chronic Obstructive
Genetic polymorphisms of matrix metalloproteinases and protein levels in chronic obstructive pulmonary disease in a Mexican population.
Pulmonary Disease, Chronic Obstructive
Glucocorticosteroids Differentially Regulate MMP-9 and Neutrophil Elastase in COPD.
Pulmonary Disease, Chronic Obstructive
Identification of patients with chronic obstructive pulmonary disease (COPD) by measurement of plasma biomarkers.
Pulmonary Disease, Chronic Obstructive
Impact of acute exposure to tobacco smoke on gelatinases in the bronchoalveolar space.
Pulmonary Disease, Chronic Obstructive
Increased activity of matrix metalloproteinase-8 and matrix metalloproteinase-9 in induced sputum from patients with COPD.
Pulmonary Disease, Chronic Obstructive
Induced sputum metalloproteinases and their inhibitors in relation to exhaled nitrogen oxide and sputum nitric oxides and other inflammatory cytokines in patients with chronic obstructive pulmonary disease.
Pulmonary Disease, Chronic Obstructive
Levels of angiopoietins 1 and 2 in induced sputum supernatant in patients with COPD.
Pulmonary Disease, Chronic Obstructive
Matrix metalloproteinase-2 protein in lung periphery is related to COPD progression.
Pulmonary Disease, Chronic Obstructive
Matrix metalloproteinases in the pathogenesis of asthma and COPD: implications for therapy.
Pulmonary Disease, Chronic Obstructive
MMP-2 (-1306 C/T) Polymorphism Affects Serum Matrix Metalloproteinase (MMP)-2 Levels and Correlates with Chronic Obstructive Pulmonary Disease Severity: A Case-Control Study of MMP-1 and -2 in a Tunisian Population.
Pulmonary Disease, Chronic Obstructive
MMP-2- and MMP-9-linked gelatinolytic activity in the sputum from patients with asthma and chronic obstructive pulmonary disease.
Pulmonary Disease, Chronic Obstructive
MMP-9 as a marker of inflammation in tracheal epithelial lining fluid (TELF) and in bronchoalveolar fluid (BALF) of COPD horses.
Pulmonary Disease, Chronic Obstructive
MMP-9 protein level does not reflect overall MMP activity in the airways of patients with COPD.
Pulmonary Disease, Chronic Obstructive
Non-small cell lung cancer is characterised by a distinct inflammatory signature in serum compared with chronic obstructive pulmonary disease.
Pulmonary Disease, Chronic Obstructive
Prothymosin ? overexpression contributes to the development of pulmonary emphysema.
Pulmonary Disease, Chronic Obstructive
Simultaneous up-regulation of matrix metalloproteinases 1, 2, 3, 7, 8, 9 and tissue inhibitors of metalloproteinases 1, 4 in serum of patients with chronic obstructive pulmonary disease.
Pulmonary Disease, Chronic Obstructive
The BRD4 inhibitor JQ1 protects against chronic obstructive pulmonary disease in mice by suppressing NF-?B activation.
Pulmonary Disease, Chronic Obstructive
The cyclooxygenase-2-prostaglandin e2 pathway maintains senescence of chronic obstructive pulmonary disease fibroblasts.
Pulmonary Disease, Chronic Obstructive
TLR9 expression is required for the development of cigarette smoke-induced emphysema in mice.
Pulmonary Disease, Chronic Obstructive
[Expressions of cyclooxygenase-2 and matrix metalloproteinase-2 and airflow obstruction in patients with chronic obstructive pulmonary disease]
Pulmonary Disease, Chronic Obstructive
[Study on effect of anemoside B4 in improving COPD rats by regulating IL-12/STAT4 and IL-4/STAT6 signaling pathways].
Pulmonary Disease, Chronic Obstructive
[The role of matrix metalloproteinases in extracellular matrix remodelling in chronic obstructive pulmonary disease rat models]
Pulmonary Edema
Hyperoxia induces interstitial (type I) and increases type IV collagenase mRNA expression and increases type I and IV collagenolytic activity in newborn rat lung.
Pulmonary Emphysema
Matrix metalloproteinase-mediated extracellular matrix protein degradation in human pulmonary emphysema.
Pulmonary Eosinophilia
Clinical findings, bronchoalveolar lavage fluid cytology and matrix metalloproteinase-2 and -9 in canine pulmonary eosinophilia.
Pulmonary Fibrosis
Activity of matrix metalloproteinase in airway epithelial cells of COPD patients.
Pulmonary Fibrosis
Artesunate modulates expression of matrix metalloproteinases and their inhibitors as well as collagen-IV to attenuate pulmonary fibrosis in rats.
Pulmonary Fibrosis
C-C chemokine receptor 2 (CCR2) deficiency improves bleomycin-induced pulmonary fibrosis by attenuation of both macrophage infiltration and production of macrophage-derived matrix metalloproteinases.
Pulmonary Fibrosis
Early and late changes of MMP-2 and MMP-9 in bleomycin-induced pulmonary fibrosis.
Pulmonary Fibrosis
Effect of antisense TIMP-1 cDNA on the expression of TIMP-1 and MMP-2 in lung tissue with pulmonary fibrosis induced by bleomycin.
Pulmonary Fibrosis
Effects of Chinese herbal medicine Shenlong Decoction on mRNA expressions of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-1 in lung tissue of rats with pulmonary fibrosis induced by bleomycin.
Pulmonary Fibrosis
Gelatinase B is required for alveolar bronchiolization after intratracheal bleomycin.
Pulmonary Fibrosis
Inhibitory effects of total ginsenoside on bleomycin-induced pulmonary fibrosis in mice.
Pulmonary Fibrosis
Matrix proteases, green tea, and St. John's wort: biomedical research catches up with folk medicine.
Pulmonary Fibrosis
Relaxin attenuates silica-induced pulmonary fibrosis by regulating collagen type I and MMP-2.
Pulmonary Fibrosis
Role of MMP-2 in alveolar epithelial cell repair after bleomycin administration in rabbits.
Pulmonary Fibrosis
The effects of taurochenodeoxycholic acid in preventing pulmonary fibrosis in mice.
Pulmonary Fibrosis
Time course of matrix metalloproteases and tissue inhibitors in bleomycin-induced pulmonary fibrosis.
Pulmonary Fibrosis
Unbalanced MMP/TIMP-1 expression during the development of experimental pulmonary fibrosis with acute paraquat poisoning.
Pulmonary Fibrosis
[Anti-type IV collagenase single-chain antibody ameliorates bleomycin-induced experimental pulmonary fibrosis in mice]
Pulmonary Fibrosis
[Changes of matrix metalloproteinases activities in pulmonary fibrosis rats]
Pulmonary Fibrosis
[Effects of Fuzheng Huayu recipe on MMP-2 activity and type IV collagen expression at fibrotic lung]
Pulmonary Fibrosis
[Inhibition of pulmonary fibrosis by doxycycline: an experiment with mice]
Pulmonary Fibrosis
[mRNA expression of matrix metalloproteinase-2 and membrane type matrix metalloproteinase in pulmonary fibroblasts and macrophages of rat pulmonary fibrosis model]
Pulmonary Fibrosis
[Perindopril and losartan attenuate bleomycin A5-induced pulmonary fibrosis in rats]
Pycnodysostosis
Collagenase activity of cathepsin K depends on complex formation with chondroitin sulfate.
Pyelonephritis
Diagnostic accuracy of urine neutrophil gelatinase-associated lipocalin and urine kidney injury molecule-1 as predictors of acute pyelonephritis in young children with febrile urinary tract infection.
Pyelonephritis
Mitochondria-Associated Matrix Metalloproteinases 2 and 9 in Acute Renal Pathologies.
Pyelonephritis
Predictive Accuracy of Urinary neutrophil gelatinase associated lipocalin (NGAL) for renal parenchymal involvement in Children with Acute Pyelonephritis.
Pyelonephritis
Urinary Measurement of Neutrophil Gelatinase Associated Lipocalin and Kidney Injury Molecule-1 Helps Diagnose Acute Pyelonephritis in a Preclinical Model.
Pyelonephritis
Validity of Neutrophil Gelatinase Associated Lipocaline as a Biomarker for Diagnosis of Children with Acute Pyelonephritis.
Radicular Cyst
Correlation between radiographic area and immunolocation of MMP-2 and MMP-9 in unilocular radiographic lesions.
Radicular Cyst
Gene-expression analysis of matrix metalloproteinases 1 and 2 and their tissue inhibitors in chronic periapical inflammatory lesions.
Radicular Cyst
Laminin-5 gamma 2 chain is colocalized with gelatinase-A (MMP-2) and collagenase-3 (MMP-13) in odontogenic keratocysts.
Radicular Cyst
Metalloproteinases 2 and 9 Immunoexpression in Periapical Lesions from Primary Endodontic Infection: Possible Relationship with the Histopathological Diagnosis and the Presence of Pain.
Radicular Cyst
Presence of myofibroblasts and matrix metalloproteinase 2 in radicular cysts, dentigerous cysts, and keratocystic odontogenic tumors: a comparative immunohistochemical study.
Rectal Neoplasms
Activity and expression of urokinase-type plasminogen activator and matrix metalloproteinases in human colorectal cancer.
Rectal Neoplasms
Gelatinase B expression as a prognostic factor in patients with stage II/III rectal carcinoma treated by postoperative adjuvant therapy.
Rectal Neoplasms
High formation of superoxide anion and nitric oxide, and matrix metalloproteinases activity in vascular wall of rectal carcinoma vessels.
Rectal Neoplasms
Increased type-IV collagenase (MMP-2 and MMP-9) activity following preoperative radiotherapy in rectal cancer.
Rectal Neoplasms
Pretreatment Expression of 13 Molecular Markers as a Predictor of Tumor Responses After Neoadjuvant Chemoradiation in Rectal Cancer.
Rectal Neoplasms
Prognostic significance of matrix metalloproteinases-1, -2, -7 and -13 and tissue inhibitors of metalloproteinases-1, -2, -3 and -4 in colorectal cancer.
Rectal Neoplasms
The matrix metalloproteinase-7 and pro-enzyme of metalloproteinase-1 as a potential marker for patients with rectal cancer without distant metastasis.
Rectal Neoplasms
[Matrix metalloproteinase-2 expression and its correlation with mesorectal metastasis in middle and lower rectal cancer]
Refractive Errors
Assessment of the association of matrix metalloproteinases with myopia, refractive error and ocular biometric measures in an Australian cohort.
Refractive Errors
Effect of Bilberry Extract on Development of Form-Deprivation Myopia in the Guinea Pig.
Renal Insufficiency
Adenylyl cyclase-associated protein-1/CAP1 as a biological target substrate of gelatinase B/MMP-9.
Renal Insufficiency
Increased expression of HIF-1alpha, VEGF-A and its receptors, MMP-2, TIMP-1, and ADAMTS-1 at the venous stenosis of arteriovenous fistula in a mouse model with renal insufficiency.
Renal Insufficiency
Matrix metalloproteinase 2 and basement membrane integrity: a unifying mechanism for progressive renal injury.
Renal Insufficiency
MMP-2 and TIMP-2 in Patients with Heart Failure and Chronic Kidney Disease.
Renal Insufficiency
Systematic separation and purification of elastase, gelatinase (matrix metalloproteinase 9), and collagenase (matrix metalloproteinase 8) from polymorphonuclear leukocytes in dialyzers previously used by patients with renal failure.
Renal Insufficiency, Chronic
Chronic humoral rejection of human kidney allografts is associated with MMP-2 accumulation in podocytes and its release in the urine.
Renal Insufficiency, Chronic
Circulating Matrix Metalloproteinase-2 Is an Independent Correlate of Proteinuria in Patients with Chronic Kidney Disease.
Renal Insufficiency, Chronic
Circulating matrix metalloproteinase-2 is associated with cystatin C level, posttransplant duration, and diabetes mellitus in kidney transplant recipients.
Renal Insufficiency, Chronic
Determinants of circulating matrix metalloproteinase-2 and pregnancy-associated plasma protein-A in patients with chronic kidney disease.
Renal Insufficiency, Chronic
Early Postoperative Neutrophil Gelatinase Associated Lipocalin Predicts the Development of Chronic Kidney Disease Following Liver Transplantation.
Renal Insufficiency, Chronic
Expression of matrix metalloproteinases MMP-2 and MMP-9 is altered during nephrogenesis in fetuses from diabetic rats.
Renal Insufficiency, Chronic
Hypoxia Activates Src and Promotes Endocytosis Which Decreases MMP-2 Activity and Aggravates Renal Interstitial Fibrosis.
Renal Insufficiency, Chronic
Matrix metalloproteinase -2, -9 and arterial stiffness in children and adolescents: The role of chronic kidney disease, diabetes, and hypertension.
Renal Insufficiency, Chronic
Matrix Metalloproteinase 2 and Osteoprotegrin as New Markers of Increased Atherosclerotic Risk in Egyptian Patients with Chronic Kidney Disease.
Renal Insufficiency, Chronic
Matrix metalloproteinase-2 and -9 exacerbate arterial stiffening and angiogenesis in diabetes and chronic kidney disease.
Renal Insufficiency, Chronic
Matrix metalloproteinases and their role in the renal epithelial mesenchymal transition.
Renal Insufficiency, Chronic
MMP-2 and TIMP-2 in Patients with Heart Failure and Chronic Kidney Disease.
Renal Insufficiency, Chronic
Novel indicators of fibrosis-related complications in children with chronic kidney disease.
Renal Insufficiency, Chronic
Peripheral blood level alterations of MMP-2 and MMP-9 in patients with chronic kidney disease on conservative treatment and on hemodialysis.
Renal Insufficiency, Chronic
Relationships between circulating matrix metalloproteinase-2 and -9 and renal function in patients with chronic kidney disease.
Renal Insufficiency, Chronic
Serum metalloproteinases MMP-2, MMP-9 and metalloproteinase tissue inhibitors TIMP-1 and TIMP-2 in patients on hemodialysis.
Renal Insufficiency, Chronic
The expression of two isoforms of matrix metalloproteinase-2 in aged mouse models of diabetes mellitus and chronic kidney disease.
Renal Insufficiency, Chronic
Upregulation of matrix metalloproteinase-2 in the arterial vasculature contributes to stiffening and vasomotor dysfunction in patients with chronic kidney disease.
Reperfusion Injury
Calpain inhibitors exhibit matrix metalloproteinase-2 inhibitory activity.
Reperfusion Injury
Cardiac ischemia-reperfusion injury induces matrix metalloproteinase-2 expression through the AP-1 components FosB and JunB.
Reperfusion Injury
Degradation of myosin light chain in isolated rat hearts subjected to ischemia-reperfusion injury: a new intracellular target for matrix metalloproteinase-2.
Reperfusion Injury
Distribution and activation of matrix metalloproteinase-2 in skeletal muscle fibers.
Reperfusion Injury
Doxycycline Reduces Cardiac Matrix Metalloproteinase-2 Activity but Does not Ameliorate Myocardial Dysfunction During Reperfusion in Coronary Artery Bypass Patients Undergoing Cardiopulmonary Bypass.
Reperfusion Injury
Imbalance between tissue inhibitor of metalloproteinase-4 and matrix metalloproteinases during acute myocardial [correction of myoctardial] ischemia-reperfusion injury.
Reperfusion Injury
Increased matrix metalloproteinase 9 activity and mRNA expression in lung ischemia-reperfusion injury.
Reperfusion Injury
Inhibition of MMP-2 expression with siRNA increases baseline cardiomyocyte contractility and protects against simulated ischemic reperfusion injury.
Reperfusion Injury
Intracellular action of matrix metalloproteinase-2 accounts for acute myocardial ischemia and reperfusion injury.
Reperfusion Injury
Intracellular Localization in Zebrafish Muscle and Conserved Sequence Features Suggest Roles for Gelatinase A Moonlighting in Sarcomere Maintenance.
Reperfusion Injury
Ischemia-reperfusion injury stimulates gelatinase expression and activity in kidney glomeruli.
Reperfusion Injury
Junctophilin-2 is a target of matrix metalloproteinase-2 in myocardial ischemia-reperfusion injury.
Reperfusion Injury
Matrix metalloproteinase inhibitor (ONO-4817) attenuates ischemia-reperfusion injury in rat lung.
Reperfusion Injury
Matrix Metalloproteinase-2 (MMP-2) Gene Deletion Enhances MMP-9 Activity, Impairs PARP-1 Degradation, and Exacerbates Hepatic Ischemia and Reperfusion Injury in Mice.
Reperfusion Injury
Matrix metalloproteinase-2 and myocardial oxidative stress injury: beyond the matrix.
Reperfusion Injury
Matrix metalloproteinase-2 contributes to ischemia-reperfusion injury in the heart.
Reperfusion Injury
Matrix metalloproteinase-2: an emerging biomarker for reperfusion injury following percutaneous coronary intervention.
Reperfusion Injury
Myocardial MMP-2 contributes to SERCA2a proteolysis during cardiac ischemia-reperfusion injury.
Reperfusion Injury
N-terminal truncated intracellular matrix metalloproteinase-2 induces cardiomyocyte hypertrophy, inflammation and systolic heart failure.
Reperfusion Injury
Novel intracellular N-terminal truncated matrix metalloproteinase-2 isoform in skeletal muscle ischemia-reperfusion injury.
Reperfusion Injury
Serum matrix metalloproteinase MMP-2 and MMP-9 in the late phase of ischemia and reperfusion injury in human orthotopic liver transplantation.
Reperfusion Injury
Structure and proteolytic susceptibility of the inhibitory C-terminal tail of cardiac troponin I.
Reperfusion Injury
Up-regulation of MMP-2 and MMP-9 leads to degradation of type IV collagen during skeletal muscle reperfusion injury; protection by the MMP inhibitor, doxycycline.
Reperfusion Injury
Vasogenic edema due to tight junction disruption by matrix metalloproteinases in cerebral ischemia.
Respiratory Distress Syndrome
Higher concentrations of matrix metalloproteinases in bronchoalveolar lavage fluid of patients with adult respiratory distress syndrome.
Respiratory Distress Syndrome
Matrix metalloproteinases and TIMP in acute respiratory distress syndrome.
Respiratory Distress Syndrome
Role of gelatinases MMP-2 and MMP-9 in tissue remodeling following acute lung injury.
Respiratory Hypersensitivity
Protective effects of tiotropium alone or combined with budesonide against cadmium inhalation induced acute neutrophilic pulmonary inflammation in rats.
Respiratory Insufficiency
Implications for matrix metalloproteinases as modulators of pediatric lung disease.
Respiratory Insufficiency
Mutations in two matrix metalloproteinase genes, MMP-2 and MT1-MMP, are synthetic lethal in mice.
Respiratory Tract Diseases
Gelatinolytic matrix metalloproteinases-2 and -9 in tracheobronchial lavage fluid obtained from calves with concurrent infections of Pasteurella multocida and Mycoplasma bovirhinis.
Retinal Degeneration
Matrix Metalloproteinases MMP-2 and MMP-9, Their Inhibitors TIMP-1 and TIMP-2, Vascular Endothelial Growth Factor and sVEGFR-2 as Predictive Markers of Ischemic Retinopathy in Patients with Systemic Sclerosis-Case Series Report.
Retinal Detachment
A feasible tool to detect mRNA expression of matrix metalloproteinases and their tissue inhibitors in human Tenon's capsule.
Retinal Detachment
Potential Role of Zinc Dyshomeostasis in Matrix Metalloproteinase-2 and -9 Activation and Photoreceptor Cell Death in Experimental Retinal Detachment.
Retinal Detachment
Predominance of MMP-1 and MMP-2 in epiretinal and subretinal membranes of proliferative vitreoretinopathy.
Retinal Detachment
Statins in rhegmatogenous retinal detachment are associated with low intravitreal angiopoietin-2, VEGF and MMP-2 levels, and improved visual acuity gain in vitrectomized patients.
Retinal Dystrophies
Matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-1 in the retinal pigment epithelium and interphotoreceptor matrix: vectorial secretion and regulation.
Retinal Neoplasms
Gelatinase expression in Retinoblastoma: Modulation of LHBETATAG retinal tumor development by Anecortave Acetate.
Retinal Neovascularization
Angiopoietin/Tek interactions regulate mmp-9 expression and retinal neovascularization.
Retinal Neovascularization
ASSESSMENT OF GELATINASE AND TUMOR NECROSIS FACTOR-? LEVEL IN THE VITREOUS AND SERUM OF PATIENTS WITH EALES DISEASE: Role of Inflammation-Mediated Angiogenesis in the Pathogenesis of Eales Disease.
Retinal Neovascularization
Inhibitory effects of arresten on bFGF-induced proliferation, migration, and matrix metalloproteinase-2 activation in mouse retinal endothelial cells.
Retinal Neovascularization
Interaction between iNOS and COX-2 in hypoxia-induced retinal neovascularization in mice.
Retinal Neovascularization
Pharmacologic and genetic manipulation of MMP-2 and -9 affects retinal neovascularization in rodent models of OIR.
Retinal Neovascularization
Retinal vascular development and pathologic retinal angiogenesis are not impaired in matrix metalloproteinase-2 deficient mice.
Retinal Neovascularization
VEGF Secreted by Hypoxic Muller Cells Induces MMP-2 Expression and Activity in Endothelial Cells to Promote Retinal Neovascularization in Proliferative Diabetic Retinopathy.
Retinal Perforations
Ang-2 upregulation correlates with increased levels of MMP-9, VEGF, EPO and TGF?1 in diabetic eyes undergoing vitrectomy.
Retinal Perforations
Interleukin-1-beta changes the expression of metalloproteinases in the vitreous humor and induces membrane formation in eyes containing preexisting retinal holes.
Retinal Perforations
Vitreous TIMP-1 levels associate with neovascularization and TGF-?2 levels but not with fibrosis in the clinical course of proliferative diabetic retinopathy.
Retinal Vein Occlusion
Association of MMP2-1306C/T and TIMP2G-418C polymorphisms in retinal vein occlusion.
Retinal Vein Occlusion
Association of MMP2-1306C/T Polymorphism with Ischemic Retinal Vein Occlusion.
Retinoblastoma
Antineoplastic activity of a nutrient mixture in Y-79 malignant retinoblastoma cells.
Retinoblastoma
Characterization and novel activation of 72-kDa metalloproteinase in retinal interphotoreceptor matrix and Y-79 cell culture medium.
Retinoblastoma
Clinicohistopathological implications of MMP/VEGF expression in retinoblastoma: a combined meta-analysis and bioinformatics analysis.
Retinoblastoma
Curcumin suppressed proliferation and migration of human retinoblastoma cells through modulating NF-?B pathway.
Retinoblastoma
Differential roles of matrix metalloproteinase-9 and -2, depending on proliferation or differentiation of retinoblastoma cells.
Retinoblastoma
Emodin inhibits vascular endothelial growth factor-A-induced angiogenesis by blocking receptor-2 (KDR/Flk-1) phosphorylation.
Retinoblastoma
FoxM1 affects adhesive, migratory, and invasive abilities of human retinoblastoma Y-79 cells by targeting matrix metalloproteinase 2.
Retinoblastoma
Gelatinase expression in Retinoblastoma: Modulation of LHBETATAG retinal tumor development by Anecortave Acetate.
Retinoblastoma
HOW EXPRESSIONS OF CLAUDIN-1 AND MMP-2 IN RETINOBLASTOMA CORRELATE WITH HISTOLOGICAL DIFFERENTIATION AND OPTIC NERVE INVASION.
Retinoblastoma
Inhibition of MMP-2 and MMP-9 decreases cellular migration, and angiogenesis in in vitro models of retinoblastoma.
Retinoblastoma
Insights on ornithine decarboxylase silencing as a potential strategy for targeting retinoblastoma.
Retinoblastoma
Loss of dipeptidyl peptidase IV immunostaining discriminates malignant melanomas from deep penetrating nevi.
Retinoblastoma
Suppressor of Zeste 12 homolog RNA interference inhibits retinoblastoma cell invasion.
Retinopathy of Prematurity
Pharmacologic and genetic manipulation of MMP-2 and -9 affects retinal neovascularization in rodent models of OIR.
Rhabdomyolysis
Mitochondria-Associated Matrix Metalloproteinases 2 and 9 in Acute Renal Pathologies.
Rhabdomyosarcoma
Coexpression of glucose transporter 1 and matrix metalloproteinase-2 in human cancers.
Rhabdomyosarcoma
Fibronectin-induced COX-2 mediates MMP-2 expression and invasiveness of rhabdomyosarcoma.
Rhabdomyosarcoma
In vitro modulation of MMP-2 and MMP-9 in pediatric human sarcoma cell lines by cytokines, inducers and inhibitors.
Rhabdomyosarcoma
Matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 expression in paediatric tumour cells. Effects of tumour cell proliferation modulators on gelatinolytic activity.
Rhabdomyosarcoma
Modulation of u-PA, MMPs and their inhibitors by a novel nutrient mixture in pediatric human sarcoma cell lines.
Rhabdomyosarcoma
Vasculogenic mimicry is a major feature and novel predictor of poor prognosis in patients with orbital rhabdomyosarcoma.
Rheumatic Diseases
Neutrophil gelatinase levels in plasma and synovial fluid of patients with rheumatic diseases.
Rhinitis
Expression of Matrix Metalloproteinases and Their Tissue Inhibitors in Chronic Rhinosinusitis With Nasal Polyps: Etiopathogenesis and Recurrence.
Rhinitis, Allergic
Expression of Matrix Metalloproteinases and Their Tissue Inhibitors in Chronic Rhinosinusitis With Nasal Polyps: Etiopathogenesis and Recurrence.
Rhinitis, Allergic
Nonasthmatic nasal polyposis patients with allergy exhibit greater epithelial MMP positivity.
Rhinitis, Allergic
Suppression of matrix metalloproteinase production in nasal fibroblasts by tranilast, an antiallergic agent, in vitro.
Rickets
Expression of chicken 75-kDa gelatinase B-like enzyme in perivascular chondrocytes suggests its role in vascularization of the growth plate.
Rickets
Expression of matrix metalloproteinases during vascularization and ossification of normal and impaired avian growth plate.
Rosacea
Tear fluid gelatinase B activity correlates with IL-1alpha concentration and fluorescein clearance in ocular rosacea.
Salivary Gland Neoplasms
The MMP-2 and MMP-9 promoter polymorphisms and susceptibility to salivary gland cancer.
Sarcoglycanopathies
Cleavage of ?-dystroglycan occurs in sarcoglycan-deficient skeletal muscle without MMP-2 and MMP-9.
Sarcoidosis
Increased production of matrix metalloproteinase-2 in alveolar macrophages and regulation by interleukin-10 in patients with acute pulmonary sarcoidosis.
Sarcoidosis
Matrix metalloproteinases and their tissue inhibitors in the lesions of cardiac and pulmonary sarcoidosis: an immunohistochemical study.
Sarcoidosis
Metalloproteinases MMP-9, MMP-2 and their tissue inhibitors TIMP-1, TIMP-2 in peripheral transbronchial lung biopsies of patients with sarcoidosis.
Sarcoidosis, Pulmonary
Increased production of matrix metalloproteinase-2 in alveolar macrophages and regulation by interleukin-10 in patients with acute pulmonary sarcoidosis.
Sarcoma
A phase II and pharmacological study of the matrix metalloproteinase inhibitor (MMPI) COL-3 in patients with advanced soft tissue sarcomas.
Sarcoma
CD73 complexes with emmprin to regulate MMP-2 production from co-cultured sarcoma cells and fibroblasts.
Sarcoma
Emmprin in epithelioid sarcoma: expression in tumor cell membrane and stimulation of MMP-2 production in tumor-associated fibroblasts.
Sarcoma
Emmprin, released as a microvesicle in epithelioid sarcoma, interacts with fibroblasts.
Sarcoma
Enzymatic processing of collagen IV by MMP-2 (gelatinase A) affects neutrophil migration and it is modulated by extracatalytic domains.
Sarcoma
Expression and activity of vascular endothelial growth factor and metalloproteinases in alveolar and embryonal rhabdomyosarcoma cell lines.
Sarcoma
Expression of matrix metalloproteinases-2, -8, -13, -26, and tissue inhibitors of metalloproteinase-1 in human osteosarcoma.
Sarcoma
Expression of metalloproteinases endometrial stromal sarcoma: immunohistochemical study using image analysis.
Sarcoma
Gelatinase and inhibitor expression in soft tissue sarcomas: lack of correlation with distant metastasis.
Sarcoma
In vitro modulation of MMP-2 and MMP-9 in adult human sarcoma cell lines by cytokines, inducers and inhibitors.
Sarcoma
In vitro modulation of MMP-2 and MMP-9 in pediatric human sarcoma cell lines by cytokines, inducers and inhibitors.
Sarcoma
Matrix metalloproteinase expression is related to angiogenesis and histologic grade in spindle cell soft tissue neoplasms of the extremities.
Sarcoma
PIK3R3, part of the regulatory domain of PI3K, is upregulated in sarcoma stem-like cells and promotes invasion, migration, and chemotherapy resistance.
Sarcoma
Proteolytic enzymes in tumor metastasis. II. Collagenase type IV activity in subcellular fractions of cloned tumor cell populations.
Sarcoma
Quercetin inhibits migration and invasion of SAS human oral cancer cells through inhibition of NF-?B and matrix metalloproteinase-2/-9 signaling pathways.
Sarcoma
Regulation of gelatinase production and invasiveness by organ-specific fibroblasts in high- and low-metastatic clones from murine RCT sarcoma.
Sarcoma
Significance of serum type IV collagenolytic activities and gelatinase levels for detection of metastasis in murine RCT sarcoma.
Sarcoma
Synthetic emmprin peptides inhibit tumor cell-fibroblast interaction-stimulated upregulation of MMP-2 and tumor cell invasion.
Sarcoma
SZ-117, a monoclonal antibody against matrix metalloproteinase-2 inhibits tumor cell-mediated angiogenesis.
Sarcoma
The effect of microRNA-330 replacement on inhibition of growth and migration in renal cancer cells.
Sarcoma 180
Differential inductions of matrix metalloproteinase-2 and -9 in host tissues during the growth of ascitic sarcoma 180 cells in mice.
Sarcoma, Avian
Cloning of a 72 kDa matrix metalloproteinase (gelatinase) from chicken embryo fibroblasts using gene family PCR: expression of the gelatinase increases upon malignant transformation.
Sarcoma, Avian
Cloning, expression, and characterization of chicken tissue inhibitor of metalloproteinase-2 (TIMP-2) in normal and transformed chicken embryo fibroblasts.
Sarcoma, Avian
Native TIMP-free 70 kDa progelatinase (MMP-2) secreted at elevated levels by RSV transformed fibroblasts.
Sarcoma, Avian
Resolution of TIMP-free and TIMP-complexed 70kDa progelatinase from culture medium of Rous sarcoma virus-transformed chicken embryo fibroblasts.
Sarcoma, Endometrial Stromal
Expression of metalloproteinases endometrial stromal sarcoma: immunohistochemical study using image analysis.
Sarcoma, Ewing
Antitumor effect of nutrient synergy on human osteosarcoma cells U-2OS, MNNG-HOS and Ewing's sarcoma SK-ES.1.
Sarcoma, Kaposi
Angiogenic potential in vivo by Kaposi's sarcoma cell-free supernatants and HIV-1 tat product: inhibition of KS-like lesions by tissue inhibitor of metalloproteinase-2.
Sarcoma, Myeloid
A possible role of 92 kDa type IV collagenase in the extramedullary tumor formation in leukemia.
Sarcoma, Synovial
Cancer/Testis Antigens: Expression, Regulation, Tumor Invasion, and Use in Immunotherapy of Cancers.
Sarcoma, Synovial
In vitro modulation of MMP-2 and MMP-9 in adult human sarcoma cell lines by cytokines, inducers and inhibitors.
Sarcoma, Synovial
Matrix metalloproteinase-2 expression correlates with morphological and immunohistochemical epithelial characteristics in synovial sarcoma.
Sarcoma, Synovial
Modulation of u-PA, MMPs and their inhibitors by a novel nutrient mixture in adult human sarcoma cell lines.
Sarcoma, Synovial
[Correlation between matrix metalloproteinases-2 and tissue inhibitor of metalloproteinase-2 expression, metastatic potential and tumor angiogenesis in synovial sarcoma and its prognostic significance]
Schistosomiasis
Imbalance of pro- and antifibrogenic genes and bile duct injury in murine Schistosoma mansoni infection-induced liver fibrosis.
Schistosomiasis
[Expression of matrix metalloproteinase 2 and 9 in liver tissue of patients with schistosomiasis japonica]
Schistosomiasis japonica
[Expression of matrix metalloproteinase 2 and 9 in liver tissue of patients with schistosomiasis japonica]
Scleroderma, Localized
[Systemic sclerosis and scleroderma circumscripta--disturbances of selected serum parameters which are responsible for vascular changes and CD34 expression in involved skin]
Scleroderma, Systemic
Gene expression of types I and III collagen, decorin, matrix metalloproteinases and tissue inhibitors of metalloproteinases in skin fibroblasts from patients with systemic sclerosis.
Scleroderma, Systemic
Increased gelatinase activity in systemic sclerosis dermal fibroblast cultures with unaltered gelatinase A mRNA expression.
Scoliosis
A Promoter Polymorphism of Tissue Inhibitor of Metalloproteinase-2 (TIMP-2) Gene Is Associated With Severity of Thoracic Adolescent Idiopathic Scoliosis.
Scoliosis
[Association between tissue inhibitor of metalloproteinase-2 gene polymorphism and adolescent idiopathic thoracic scoliosis]
Seizures
Antidepressant treatments regulate matrix metalloproteinases-2 and -9 (MMP-2/MMP-9) and tissue inhibitors of the metalloproteinases (TIMPS 1-4) in the adult rat hippocampus.
Seizures
Matrix metalloproteinase 9 regulates cell death following pilocarpine-induced seizures in the developing brain.
Seizures
Plasma Biomarkers of Inflammation Reflect Seizures and Hemorrhagic Activity of Cerebral Cavernous Malformations.
Seizures
Regional and differential expression of gelatinases in rat brain after systemic kainic acid or bicuculline administration.
Seminoma
Imbalance of MMP-2 and MMP-9 expression versus TIMP-1 and TIMP-2 reflects increased invasiveness of human testicular germ cell tumours.
Seminoma
Nuclear Localization of PTTG1 Promotes Migration and Invasion of Seminoma Tumor through Activation of MMP-2.
Seminoma
[Correlation between expression of metastasis-related genes and lymph node metastasis in testicular cancer]
Sepsis
Baicalein inhibits HMGB1 release and MMP-2/-9 expression in lipopolysaccharide-induced cardiac hypertrophy.
Sepsis
Effect of chemically modified tetracycline on transforming growth factor-beta1 and caspase-3 activation in liver of septic rats.
Sepsis
Investigation of the effect of melatonin administration on inflammatory mediators; MMP-2, TGF-? and VEGF levels in rats with sepsis.
Sepsis
Matrix metalloproteinase inhibitors prevent sepsis-induced refractoriness to vasoconstrictors in the cecal ligation and puncture model in rats.
Sepsis
Matrix Metalloproteinase-2 and Metalloproteinase-9 Activities are Associated with Blood-Brain Barrier Dysfunction in an Animal Model of Severe Sepsis.
Sepsis
Matrix- metalloproteinase -2, -8 and -9 in serum and skin blister fluid in patients with severe sepsis.
Sepsis
Matrix-metalloproteinases and their inhibitors are elevated in severe sepsis: prognostic value of TIMP-1 in severe sepsis.
Sepsis
Modulation of matrix metalloproteinase-9 and tissue inhibitor of matrix metalloproteinase-1 in sepsis.
Sepsis
Plasma Neutrophil Gelatinase Associated Lipocalin Diagnosed Acute Kidney Injury in Patients With Systemic Inflammatory Disease And Sepsis.
Sepsis
Serum Neutrophil Gelatinase Associated Lipocalin (NGAL) Outperforms Serum Creatinine in Detecting Sepsis-Induced Acute Kidney Injury, Experiments on Bilateral Nephrectomy and Bilateral Ureter Obstruction Mouse Models.
Sepsis
Urinary neutrophil gelatinase associated lipocalin identifies neonates with high probability of sepsis.
Sepsis
Urinary Tissue Inhibitor of Metalloproteinase-2 and Insulin-Like Growth Factor-Binding Protein 7 for Risk Stratification of Acute Kidney Injury in Patients With Sepsis.
Sepsis
Urinary [TIMP-2]?×?[IGFBP7] and serum procalcitonin to predict and assess the risk for short-term outcomes in septic and non-septic critically ill patients.
Shock, Septic
Acute actions and novel targets of matrix metalloproteinases in the heart and vasculature.
Shock, Septic
Inhibition of matrix metalloproteinases by chemically modified tetracyclines in sepsis.
Shock, Septic
Inhibition of Neutrophil Collagenase/MMP-8 and Gelatinase B/MMP-9 and Protection against Endotoxin Shock.
Shock, Septic
Targeting neutrophil collagenase/matrix metalloproteinase-8 and gelatinase B/matrix metalloproteinase-9 with a peptidomimetic inhibitor protects against endotoxin shock.
Sialadenitis
Extracellular matrix molecules in chronic obstructive sialadenitis: an immunocytochemical and Western blot investigation.
Silicosis
Expression and localization of TIMP-1, TIMP-2, MMP-13, MMP-2, and MMP-9 in early and advanced experimental lung silicosis.
Silicosis
Serum concentrations of Krebs von den Lungen-6, surfactant protein D, and matrix metalloproteinase-2 as diagnostic biomarkers in patients with asbestosis and silicosis: a case-control study.
Silicosis
[Relationship between genetic polymorphisms of matrix metalloproteinase-2 and -3 and susceptibility to silicosis].
Silicosis
[The discriminant analysis of the silicosis's induction on cytokines in phlegm and combined multi-markers].
Skin Diseases
Cytokine and Chemokine Profile in Amicrobial Pustulosis of the Folds: Evidence for Autoinflammation.
Skin Diseases
Demonstration of 72-kDa and 92-kDa forms of type IV collagenase in human skin: variable expression in various blistering diseases, induction during re-epithelialization, and decrease by topical glucocorticoids.
Skin Neoplasms
Differential expression of matrix metalloproteinase (MMP)-2, MMP-9 and tissue inhibitor of metalloproteinase (TIMP)-1 and TIMP-2 in non-melanoma skin cancer: implications for tumour progression.
Skin Neoplasms
Ferulic acid, a phenolic phytochemical, inhibits UVB-induced matrix metalloproteinases in mouse skin via posttranslational mechanisms.
Skin Neoplasms
Plant derived coumestrol phytochemical targets human skin carcinoma cells by inducing mitochondrial-mediated apoptosis, cell cycle arrest, inhibition of cell migration and invasion and modulation of m-TOR/PI3K/AKT signalling pathway.
Skin Neoplasms
[VALUE OF METALPROTEINASES OF BLOOD IN PATHOGENESIS OF EPITELIAL SKIN TUMORS AND THE POSSIBILITY OF THEIR SURGICAL CORRECTION].
Sleep Apnea, Obstructive
Association between plasma neutrophil gelatinase associated lipocalin level and obstructive sleep apnea or nocturnal intermittent hypoxia.
Sleep Apnea, Obstructive
Functional polymorphisms in the promoter region of MMP-2 and MMP-9 and susceptibility to obstructive sleep apnea.
Sleep Apnea, Obstructive
Serum matrix metalloproteinase-2 as a predictor of level of hypoxemia and severity of obstructive sleep apnea.
Sleep Initiation and Maintenance Disorders
Inflammatory Biomarkers, Hematopoietic Stem Cells, and Symptoms in Breast Cancer Patients Undergoing Adjuvant Radiation Therapy.
Small Cell Lung Carcinoma
Absence of CD9 enhances adhesion-dependent morphologic differentiation, survival, and matrix metalloproteinase-2 production in small cell lung cancer cells.
Small Cell Lung Carcinoma
Gelatin-degrading type IV collagenase isolated from human small cell lung cancer.
Smear Layer
Tetracycline at subcytotoxic levels inhibits matrix metalloproteinase-2 and -9 but does not remove the smear layer.
Smooth Muscle Tumor
Expression of matrix metalloproteinases in patients with uterine smooth muscle tumors: an immunohistochemical analysis of MMP-1 and MMP-2 protein expression in leiomyoma, uterine smooth muscle tumor of uncertain malignant potential, and leiomyosarcoma.
Soft Tissue Infections
Human Neutrophil Granule Exocytosis in Response to Mycobacterium smegmatis.
Soft Tissue Neoplasms
Matrix metalloproteinase expression is related to angiogenesis and histologic grade in spindle cell soft tissue neoplasms of the extremities.
Solitary Fibrous Tumors
Expression of CD44 and MMP-2: possible association with histopathological features of pleuro-pulmonary solitary fibrous tumors.
Spinal Cord Diseases
Immunohistochemical Profile of NF-?B/p50, NF-?B/p65, MMP-9, MMP-2 and u-PA in Experimental Cervical Spondylotic Myelopathy.
Spinal Cord Injuries
A nutrient mixture reduces the expression of matrix metalloproteinases in an animal model of spinal cord injury by modulating matrix metalloproteinase-2 and matrix metalloproteinase-9 promoter activities.
Spinal Cord Injuries
Activation of matrix metalloproteinases-9 after photothrombotic spinal cord injury model in rats.
Spinal Cord Injuries
Downregulation of Matrix Metalloproteinases 2 and 9 is Involved in the Protective Effect of Trehalose on Spinal Cord Injury.
Spinal Cord Injuries
Effects of hyperbaric oxygen on MMP-2 and MMP-9 expression and spinal cord edema after spinal cord injury.
Spinal Cord Injuries
Effects of hyperbaric oxygen on MMP-2 and MMP-9 expressions and spinal cord edema after spinal cord injury.
Spinal Cord Injuries
Fluoxetine inhibits matrix metalloprotease activation and prevents disruption of blood-spinal cord barrier after spinal cord injury.
Spinal Cord Injuries
Human umbilical cord blood stem cells upregulate matrix metalloproteinase-2 in rats after spinal cord injury.
Spinal Cord Injuries
Matrix metalloproteinase-2 facilitates wound healing events that promote functional recovery after spinal cord injury.
Spinal Cord Injuries
Matrix metalloproteinases: potential therapeutic target in spinal cord injury.
Spinal Cord Injuries
Melatonin improves functional outcome via inhibition of matrix metalloproteinases-9 after photothrombotic spinal cord injury in rats.
Spinal Cord Injuries
Selective gelatinase inhibitor neuroprotective agents cross the blood-brain barrier.
Spinal Cord Injuries
Selective Inhibition of MMP-2 Does Not Alter Neurological Recovery after Spinal Cord Injury.
Spinal Dysraphism
Urinary TIMP-2 and MMP-2 are significantly associated with poor bladder compliance in adult patients with spina bifida.
Spinal Stenosis
The increased expression of matrix metalloproteinases associated with elastin degradation and fibrosis of the ligamentum flavum in patients with lumbar spinal stenosis.
Spondylitis, Ankylosing
MMP-2 silencing reduces the osteogenic transformation of fibroblasts by inhibiting the activation of the BMP/Smad pathway in ankylosing spondylitis.
Spondylitis, Ankylosing
MMP-2, TNF-? and NLRP1 polymorphisms in Chinese patients with ankylosing spondylitis and rheumatoid arthritis.
Spondylitis, Ankylosing
Neutrophil gelatinase levels in plasma and synovial fluid of patients with rheumatic diseases.
Squamous Cell Carcinoma of Head and Neck
Activation of matrix metalloproteinase-2 in head and neck squamous cell carcinoma: studies of clinical samples and in vitro cell lines co-cultured with fibroblasts.
Squamous Cell Carcinoma of Head and Neck
Activation of MMP-2 and MMP-9 in patients with oral squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Activation of Toll-Like Receptor-9 Promotes Cellular Migration via Up-Regulating MMP-2 Expression in Oral Squamous Cell Carcinoma.
Squamous Cell Carcinoma of Head and Neck
Alpha-mangostin suppresses MMP-2 and MMP-9 expression in head and neck squamous carcinoma cells.
Squamous Cell Carcinoma of Head and Neck
Analysis of expression of matrix metalloproteinases-2 and -9 in hypopharyngeal squamous cell carcinoma by in situ hybridization.
Squamous Cell Carcinoma of Head and Neck
Anti-cancer Effect of 20(S)-Ginsenoside-Rh2 on Oral Squamous Cell Carcinoma Cells via the Decrease in ROS and Downregulation of MMP-2 and VEGF.
Squamous Cell Carcinoma of Head and Neck
Antimetastatic Effects of Sesamin on Human Head and Neck Squamous Cell Carcinoma through Regulation of Matrix Metalloproteinase-2.
Squamous Cell Carcinoma of Head and Neck
Antimetastatic potentials of salvianolic acid A on oral squamous cell carcinoma by targeting MMP-2 and the c-Raf/MEK/ERK pathway.
Squamous Cell Carcinoma of Head and Neck
Blockage of Squamous Cancer Cell Collective Invasion by FAK Inhibition Is Released by CAFs and MMP-2.
Squamous Cell Carcinoma of Head and Neck
Cancer/Testis Antigens: Expression, Regulation, Tumor Invasion, and Use in Immunotherapy of Cancers.
Squamous Cell Carcinoma of Head and Neck
Clinical significance of expression of membrane type 1 matrix metalloproteinase and matrix metalloproteinase-2 in human head and neck squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Combination of ACY-241 and JQ1 Synergistically Suppresses Metastasis of HNSCC via Regulation of MMP-2 and MMP-9.
Squamous Cell Carcinoma of Head and Neck
Correlation of matrix metalloproteinase-2, -9, tissue inhibitor-1 of matrix metalloproteinase and CD44 variant 6 in head and neck cancer metastasis.
Squamous Cell Carcinoma of Head and Neck
Curcumin Inhibits Invasiveness and Epithelial-Mesenchymal Transition in Oral Squamous Cell Carcinoma Through Reducing Matrix Metalloproteinase 2, 9 and Modulating p53-E-Cadherin Pathway.
Squamous Cell Carcinoma of Head and Neck
Cytokine regulation of gelatinase production by head and neck squamous cell carcinoma: the role of tumor necrosis factor-alpha.
Squamous Cell Carcinoma of Head and Neck
Differential expression of c-jun and c-fos mRNAs in squamous cell carcinoma of the head and neck: associations with uPA, gelatinase B, and matrilysin mRNAs.
Squamous Cell Carcinoma of Head and Neck
Differential regulation of membrane type 1-matrix metalloproteinase activity by ERK 1/2- and p38 MAPK-modulated tissue inhibitor of metalloproteinases 2 expression controls transforming growth factor-beta1-induced pericellular collagenolysis.
Squamous Cell Carcinoma of Head and Neck
Down-regulation of MMP-2 expression due to inhibition of receptor tyrosine kinases by imatinib and carboplatin in HNSCC.
Squamous Cell Carcinoma of Head and Neck
Downregulation of miR-21 regulates MMP-2 expression and suppress migration of Laryngeal squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
E1AF expression is closely correlated with malignant phenotype of tongue squamous cell carcinoma through activation of MT1-MMP gene promoters.
Squamous Cell Carcinoma of Head and Neck
Effects of cigarette smoke condensate on oral squamous cell carcinoma cells.
Squamous Cell Carcinoma of Head and Neck
Enhanced production and activation of progelatinase A mediated by membrane-type 1 matrix metalloproteinase in human oral squamous cell carcinomas: implications for lymph node metastasis.
Squamous Cell Carcinoma of Head and Neck
Enhanced production of matrix metalloproteinase-2 in human head and neck carcinomas is correlated with lymph node metastasis.
Squamous Cell Carcinoma of Head and Neck
Epidermal growth factor-like ligands differentially up-regulate matrix metalloproteinase 9 in head and neck squamous carcinoma cells.
Squamous Cell Carcinoma of Head and Neck
Epigallocatechin gallate sensitizes CAL-27 human oral squamous cell carcinoma cells to the anti-metastatic effects of gefitinib (Iressa) via synergistic suppression of epidermal growth factor receptor and matrix metalloproteinase-2.
Squamous Cell Carcinoma of Head and Neck
Epithelial-mesenchymal transition in oral squamous cell carcinoma triggered by transforming growth factor-beta1 is Snail family-dependent and correlates with matrix metalloproteinase-2 and -9 expressions.
Squamous Cell Carcinoma of Head and Neck
Expression and clinical significance of matrix metalloproteinase-2 and matrix metalloproteinase-9 in oral squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Expression of c-erbB receptors, MMPs and VEGF in squamous cell carcinoma of the head and neck.
Squamous Cell Carcinoma of Head and Neck
Expression of cyclooxygenase-2, vascular endothelial growth factor and matrix metalloproteinase-2 in patients with primary laryngeal carcinoma: a tissue microarray study.
Squamous Cell Carcinoma of Head and Neck
Expression of FLJ10540 is correlated with aggressiveness of oral cavity squamous cell carcinoma by stimulating cell migration and invasion through increased FOXM1 and MMP-2 activity.
Squamous Cell Carcinoma of Head and Neck
Expression of matrix metalloproteinase 1, matrix metalloproteinase 2, and matrix metalloproteinase 9 in carcinoma of the head and neck.
Squamous Cell Carcinoma of Head and Neck
Expression of matrix metalloproteinase 2 and its tissue inhibitor in oral squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Expression of matrix metalloproteinase-2 and -9 in oral squamous cell carcinomas with regard to the metastatic potential.
Squamous Cell Carcinoma of Head and Neck
Expression of matrix metalloproteinase-2 related to lymph node metastasis of oral squamous cell carcinoma. A clinicopathologic study.
Squamous Cell Carcinoma of Head and Neck
Expression of matrix metalloproteinases (MMP-2 and MMP-9) in recurrent respiratory papillomas and laryngeal carcinoma: clinical and morphological parallels.
Squamous Cell Carcinoma of Head and Neck
Fibroblast-derived MT1-MMP promotes tumor progression in vitro and in vivo.
Squamous Cell Carcinoma of Head and Neck
Fibroblasts and extracellular matrix differently modulate MMP activation by primary and metastatic head and neck cancer cells.
Squamous Cell Carcinoma of Head and Neck
Functional genotype in matrix metalloproteinases-2 promoter is a risk factor for oral carcinogenesis.
Squamous Cell Carcinoma of Head and Neck
Granulocyte-macrophage colony-stimulating factor upregulates matrix metalloproteinase-2 (MMP-2) and membrane type-1 MMP (MT1-MMP) in human head and neck cancer cells.
Squamous Cell Carcinoma of Head and Neck
Human head and neck squamous cell carcinoma cells are both targets and effectors for the angiogenic cytokine, VEGF.
Squamous Cell Carcinoma of Head and Neck
Human neutrophil peptide-1 affects matrix metalloproteinase-2, -8 and -9 secretions of oral squamous cell carcinoma cell lines in vitro.
Squamous Cell Carcinoma of Head and Neck
Hypoxia-Induced Cleavage Of Soluble ephrinA1 From Cancer Cells Is Mediated By MMP-2 And Associates With Angiogenesis In Oral Squamous Cell Carcinoma.
Squamous Cell Carcinoma of Head and Neck
Immunohistochemical expression of MMP-2 and MMP-8 in oral squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Increased expression and activation of matrix metalloproteinase-2 (MMP-2) in O-1N: hamster oral squamous cell carcinoma with high potential lymph node metastasis.
Squamous Cell Carcinoma of Head and Neck
Increased expression of matrix metalloproteinase-2 in oral cells after short-term stimulation and long-term usage of areca quid.
Squamous Cell Carcinoma of Head and Neck
Inhibition of cervical lymph node metastasis by marimastat (BB-2516) in an orthotopic oral squamous cell carcinoma implantation model.
Squamous Cell Carcinoma of Head and Neck
Inhibition of cyclooxygenase-2 suppresses invasiveness of oral squamous cell carcinoma cell lines via down-regulation of matrix metalloproteinase-2 and CD44.
Squamous Cell Carcinoma of Head and Neck
Inhibition of cyclooxygenase-2 suppresses the invasiveness of oral squamous cell carcinoma cell lines via down-regulation of matrix metalloproteinase-2 production and activation.
Squamous Cell Carcinoma of Head and Neck
Inhibition of head and neck squamous cell carcinoma growth and invasion by the calcium influx inhibitor carboxyamido-triazole.
Squamous Cell Carcinoma of Head and Neck
Inhibition of matrix metalloproteinase-2 modulates malignant behaviour of oral squamous cell carcinoma cells.
Squamous Cell Carcinoma of Head and Neck
Involvement of focal adhesion kinase in cellular invasion of head and neck squamous cell carcinomas via regulation of MMP-2 expression.
Squamous Cell Carcinoma of Head and Neck
Leptin acts on neoplastic behavior and expression levels of genes related to hypoxia, angiogenesis, and invasiveness in oral squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Levels of neutrophil gelatinase-assosciated lipocalin in patients with head and neck squamous cell carcinoma in Indian population from Haryana state.
Squamous Cell Carcinoma of Head and Neck
Matrix metalloproteinase 2 and matrix metalloproteinase 9 expression in human oral squamous cell carcinoma and the effect of protein kinase C inhibitors: preliminary observations.
Squamous Cell Carcinoma of Head and Neck
Matrix metalloproteinase-2 and -14 in p16-positive and -negative HNSCC after exposure To 5-FU and docetaxel In Vitro.
Squamous Cell Carcinoma of Head and Neck
Matrix metalloproteinase-2 and -9 activities correlate with the disease-free survival of oral squamous cell carcinoma patients.
Squamous Cell Carcinoma of Head and Neck
Matrix metalloproteinases (MMPs) and inhibitor of metalloproteinases (TIMP) mRNA and protein expression in laryngeal squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Matrix metalloproteinases and their inhibitors: correlation with invasion and metastasis in oral cancer.
Squamous Cell Carcinoma of Head and Neck
May High MMP-2 and TIMP-2 Expressions Increase or Decrease the Aggressivity of Oral Cancer?
Squamous Cell Carcinoma of Head and Neck
Metaanalysis of the significance of matrix metalloproteinases for lymph node disease in patients with head and neck squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Metalloproteinases and their inhibitors: Influence on tumor invasiveness and metastasis formation in head and neck squamous cell carcinomas.
Squamous Cell Carcinoma of Head and Neck
MMPs, TIMP-2, and TGF-beta1 in the cancerization of oral lichen planus.
Squamous Cell Carcinoma of Head and Neck
Modulation of cell growth and matrix metalloproteinase-2 activation of oral squamous cell carcinoma as a function of culture condition with type I collagen.
Squamous Cell Carcinoma of Head and Neck
Molecular pathways involved in crosstalk between cancer cells, osteoblasts and osteoclasts in the invasion of bone by oral squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
nm23-H1 suppresses invasion of oral squamous cell carcinoma-derived cell lines without modifying matrix metalloproteinase-2 and matrix metalloproteinase-9 expression.
Squamous Cell Carcinoma of Head and Neck
Oral and IV Dosages of Doxorubicin-Methotrexate loaded- Nanoparticles Inhibit Progression of Oral Cancer by Down- Regulation of Matrix Methaloproteinase 2 Expression in Vivo.
Squamous Cell Carcinoma of Head and Neck
Oral submucous fibrosis stimulates invasion and epithelial-mesenchymal transition in oral squamous cell carcinoma by activating MMP-2 and IGF-IR.
Squamous Cell Carcinoma of Head and Neck
Osteoactivin Regulates Head and Neck Squamous Cell Carcinoma Invasion by Modulating Matrix Metalloproteases.
Squamous Cell Carcinoma of Head and Neck
Overexpression of MMP-2 in laryngeal squamous cell carcinoma: a potential indicator for poor prognosis.
Squamous Cell Carcinoma of Head and Neck
Participation of fibroblasts in MMP-2 binding and activation on the surface of oral squamous cell carcinoma cells.
Squamous Cell Carcinoma of Head and Neck
Prediction of metastasis in oral squamous cell carcinoma through phenotypic evaluation and gene expression of E-cadherin, ?-catenin, matrix metalloproteinase-2, and matrix metalloproteinase-9 biomarkers with clinical correlation.
Squamous Cell Carcinoma of Head and Neck
Production of matrix metalloproteinase 2 (gelatinase/type IV collagenase) and 3 (stromelysin) by cultured oral squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Prognostic molecular markers in head and neck squamous cell carcinoma in a New Zealand population: matrix metalloproteinase-2 and sialyl Lewis x antigen.
Squamous Cell Carcinoma of Head and Neck
Prognostic significance of CXCR-4 expression in oral squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Prognostic value of matrix metalloproteinases in oral squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Prognostic value of MMP-2, -9 and TIMP-1,-2 immunoreactive protein at the invasive front in advanced head and neck squamous cell carcinomas.
Squamous Cell Carcinoma of Head and Neck
Quercetin suppresses cellular migration and invasion in human head and neck squamous cell carcinoma (HNSCC).
Squamous Cell Carcinoma of Head and Neck
Regulatory effect of MiR103 on proliferation, EMT and invasion of oral squamous carcinoma cell through SALL4.
Squamous Cell Carcinoma of Head and Neck
Relationship between the Expression of Matrix Metalloproteinase and Clinicopathologic Features in Oral Squamous Cell Carcinoma.
Squamous Cell Carcinoma of Head and Neck
Role of functional polymorphism of matrix metalloproteinase-2 (-1306 C/T and -168 G/T) and MMP-9 (-1562 C/T) promoter in oral submucous fibrosis and head and neck squamous cell carcinoma in an Indian population.
Squamous Cell Carcinoma of Head and Neck
Role of membrane type 1-matrix metalloproteinase and gelatinase A in head and neck squamous cell carcinoma invasion in vitro.
Squamous Cell Carcinoma of Head and Neck
Role of siRNA silencing of MMP-2 gene on invasion and growth of laryngeal squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
S100A8/A9 regulates MMP-2 expression and invasion and migration by carcinoma cells.
Squamous Cell Carcinoma of Head and Neck
Serum Level of Matrix Metalloproteinase-2 and -9 in Patients with Laryngeal Squamous Cell Carcinoma and Clinical Significance.
Squamous Cell Carcinoma of Head and Neck
Serum levels of matrix metalloproteinase-2 and -9 in patients with head and neck squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Skp2 Regulates the Expression of MMP-2 and MMP-9, and Enhances the Invasion Potential of Oral Squamous Cell Carcinoma.
Squamous Cell Carcinoma of Head and Neck
Strong association of the tissue inhibitor of metalloproteinase-2 polymorphism with an increased risk of oral squamous cell carcinoma in Europeans.
Squamous Cell Carcinoma of Head and Neck
The immunohistochemical characterization of MMP-2, MMP-10, TIMP-1, TIMP-2, and podoplanin in oral squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
The role of matrix metalloproteinases in squamous cell carcinomas of the head and neck.
Squamous Cell Carcinoma of Head and Neck
The upregulated ?-catulin expression was involved in head-neck squamous cell carcinogenesis by promoting proliferation, migration, invasion, and epithelial to mesenchymal transition.
Squamous Cell Carcinoma of Head and Neck
Therapy of head and neck squamous cell carcinoma with replicative adenovirus expressing tissue inhibitor of metalloproteinase-2 and chemoradiation.
Squamous Cell Carcinoma of Head and Neck
Tissue and circulating immunoreactive protein for MMP-2 and TIMP-2 in head and neck squamous cell carcinoma-tissue immunoreactivity predicts aggressive clinical course.
Squamous Cell Carcinoma of Head and Neck
Tumor-stroma interactions influence cytokine expression and matrix metalloproteinase activities in paired primary and metastatic head and neck cancer cells.
Squamous Cell Carcinoma of Head and Neck
[Expression and clinical significance of matrix metalloproteinase-2 in laryngeal squamous cell carcinoma]
Squamous Cell Carcinoma of Head and Neck
[Expressions and significances of CD147, OPN and MMP-2 in oral squamous cell carcinoma].
Squamous Intraepithelial Lesions of the Cervix
MMP-1 and MMP-2 in the cervix uteri in different steps of malignant transformation--an immunohistochemical study.
ST Elevation Myocardial Infarction
Alteplase treatment affects circulating matrix metalloproteinase concentrations in patients with ST segment elevation acute myocardial infarction.
ST Elevation Myocardial Infarction
Early measurements of plasma matrix metalloproteinase-2 predict infarct size and ventricular dysfunction in ST-elevation myocardial infarction.
ST Elevation Myocardial Infarction
Expressions and clinical significance of factors related to acute coronary syndrome.
ST Elevation Myocardial Infarction
Serum and Echocardiographic Markers May Synergistically Predict Adverse Cardiac Remodeling after ST-Segment Elevation Myocardial Infarction in Patients with Preserved Ejection Fraction.
Staphylococcal Infections
Neutralization of MMP-2 protects Staphylococcus aureus infection induced septic arthritis in mice and regulates the levels of cytokines.
Starvation
Molecular mechanisms involved in the protective effect of pituitary adenylate cyclase-activating polypeptide in an in vitro model of amyotrophic lateral sclerosis.
Status Epilepticus
Matrix Metalloproteinase-Mediated Blood-Brain Barrier Dysfunction in Epilepsy.
Stevens-Johnson Syndrome
Neutrophil Collagenase, Gelatinase, and Myeloperoxidase in Tears of Patients with Stevens-Johnson Syndrome and Ocular Cicatricial Pemphigoid.
Stevens-Johnson Syndrome
Possible involvement of gelatinase A (MMP2) and gelatinase B (MMP9) in toxic epidermal necrolysis or Stevens-Johnson syndrome.
Stomach Neoplasms
A small interfering RNA targeting osteopontin as gastric cancer therapeutics.
Stomach Neoplasms
AA-PMe, a novel asiatic acid derivative, induces apoptosis and suppresses proliferation, migration, and invasion of gastric cancer cells.
Stomach Neoplasms
Anti-cancer activity of DHA on gastric cancer-an in vitro and in vivo study.
Stomach Neoplasms
Anti-metastatic activity of fangchinoline in human gastric cancer AGS cells.
Stomach Neoplasms
Arsenic trioxide inhibits invasion/migration in SGC-7901 cells by activating the reactive oxygen species-dependent cyclooxygenase-2/matrix metalloproteinase-2 pathway.
Stomach Neoplasms
Baicalein inhibits the invasion of gastric cancer cells by suppressing the activity of the p38 signaling pathway.
Stomach Neoplasms
Bcl-w promotes gastric cancer cell invasion by inducing matrix metalloproteinase-2 expression via phosphoinositide 3-kinase, Akt, and Sp1.
Stomach Neoplasms
Blockade of CXCR6 reduces invasive potential of gastric cancer cells through inhibition of AKT signaling.
Stomach Neoplasms
CDH17 alters MMP-2 expression via canonical NF-?B signalling in human gastric cancer.
Stomach Neoplasms
Changes of histology and expression of MMP-2 and nm23-H1 in primary and metastatic gastric cancer.
Stomach Neoplasms
Circular RNA 0000096 affects cell growth and migration in gastric cancer.
Stomach Neoplasms
Claudin-4 expression in gastric cancer cells enhances the invasion and is associated with the increased level of matrix metalloproteinase-2 and -9 expression.
Stomach Neoplasms
Claudin-4 expression is associated with tumor invasion, MMP-2 and MMP-9 expression in gastric cancer.
Stomach Neoplasms
Clinical Significance of Matrix Metalloproteinases in Blood Plasma of Patients with Gastric Cancer.
Stomach Neoplasms
Clinical significance of serum levels of matrix metalloproteinase 2 (MMP-2) and its tissue inhibitor (TIMP-2) in gastric cancer.
Stomach Neoplasms
Clinical significance of tissue levels of matrix metalloproteinases and tissue inhibitors of metalloproteinases in gastric cancer.
Stomach Neoplasms
Clinicopathological significance of E-cadherin, VEGF, and MMPs in gastric cancer.
Stomach Neoplasms
Clinicopathological significance of MMP-2 and its specific inhibitor TIMP-2 in gastric cancer.
Stomach Neoplasms
Clinicopathological significance of MMP-2 and TIMP-2 genotypes in gastric cancer.
Stomach Neoplasms
Co-evolution of cancer microenvironment reveals distinctive patterns of gastric cancer invasion: laboratory evidence and clinical significance.
Stomach Neoplasms
Correlations of MMP-2 and TIMP-2 gene polymorphisms with the risk and prognosis of gastric cancer.
Stomach Neoplasms
CXCL10/CXCR3 axis promotes the invasion of gastric cancer via PI3K/AKT pathway-dependent MMPs production.
Stomach Neoplasms
Dehydroeffusol effectively inhibits human gastric cancer cell-mediated vasculogenic mimicry with low toxicity.
Stomach Neoplasms
Dextran Sulfate Effects EMT of Human Gastric Cancer Cells by Reducing HIF-1?/ TGF-?.
Stomach Neoplasms
Downregulation of CD147 by chitooligosaccharide inhibits MMP-2 expression and suppresses the metastatic potential of human gastric cancer.
Stomach Neoplasms
Downregulation of FKBP14 by RNA interference inhibits the proliferation, adhesion and invasion of gastric cancer cells.
Stomach Neoplasms
Downregulation of NDRG1 promotes invasion of human gastric cancer AGS cells through MMP-2.
Stomach Neoplasms
Downregulation of SFRP5 expression and its inverse correlation with those of MMP-7 and MT1-MMP in gastric cancer.
Stomach Neoplasms
Effect of a synthetic cannabinoid agonist on the proliferation and invasion of gastric cancer cells.
Stomach Neoplasms
Effect of glutamine-enriched nutritional support on intestinal mucosal barrier function, MMP-2, MMP-9 and immune function in patients with advanced gastric cancer during perioperative chemotherapy.
Stomach Neoplasms
Effect of hGC-MSCs from human gastric cancer tissue on cell proliferation, invasion and epithelial-mesenchymal transition in tumor tissue of gastric cancer tumor-bearing mice.
Stomach Neoplasms
Effects of angiopoietin-1 on attachment and metastasis of human gastric cancer cell line BGC-823.
Stomach Neoplasms
Effects of LY294002 on the invasiveness of human gastric cancer in vivo in nude mice.
Stomach Neoplasms
Effects of Tiam 1 on Invasive Capacity of Gastric Cancer Cells in vitro and Underlying Mechanisms.
Stomach Neoplasms
Elevated levels of serum and plasma metalloproteinases in patients with gastric cancer.
Stomach Neoplasms
Erratum: Silibinin inhibits the migration and invasion of human gastric cancer SGC7901 cells by downregulating MMP-2 and MMP-9 expression via the p38MAPK signaling pathway.
Stomach Neoplasms
Expression and correlation of CD44v6, vascular endothelial growth factor, matrix metalloproteinase-2, and matrix metalloproteinase-9 in Krukenberg tumor.
Stomach Neoplasms
Expression of collagenase-3 (matrix metalloproteinase-13) in human gastric cancer.
Stomach Neoplasms
Expression of matrix metalloproteinases MMP-2 and MMP-9 in gastric cancer and their relation to claudin-4 expression.
Stomach Neoplasms
Expression of MMP-2 is associated with progression and lymph node metastasis of gastric carcinoma.
Stomach Neoplasms
Expression of MMP-7 and MT1-MMP in peritoneal dissemination of gastric cancer.
Stomach Neoplasms
Expression of peroxisome proliferator-activated receptor g, E-cadherin and matrix metalloproteinases-2 in gastric carcinoma and lymph node metastases.
Stomach Neoplasms
Expression of PI3K/AKT pathway in gastric cancer and its blockade suppresses tumor growth and metastasis.
Stomach Neoplasms
Expression of reversion-inducing-cysteine-rich protein with Kazal motifs (RECK) as a prognostic indicator in gastric cancer.
Stomach Neoplasms
Expression of tissue levels of matrix metalloproteinases and tissue inhibitors of metalloproteinases in gastric adenocarcinoma.
Stomach Neoplasms
Expression of TRAP1 in gastric cancer tissue and its correlation with malignant biology.
Stomach Neoplasms
Expression of Vav3 protein and its prognostic value in patients with gastric cancer.
Stomach Neoplasms
Expression of Yes-associated protein in gastric adenocarcinoma and inhibitory effects of its knockdown on gastric cancer cell proliferation and metastasis.
Stomach Neoplasms
Ginkgolic acid (GA) suppresses gastric cancer growth by inducing apoptosis and suppressing STAT3/JAK2 signaling regulated by ROS.
Stomach Neoplasms
Harmine induces apoptosis and inhibits tumor cell proliferation, migration and invasion through down-regulation of cyclooxygenase-2 expression in gastric cancer.
Stomach Neoplasms
High mobility group box 1/toll-like receptor 4/myeloid differentiation factor 88 signaling promotes progression of gastric cancer.
Stomach Neoplasms
Immunoexpression of Metalloproteinases 2 and 14 and TIMP-2 Inhibitor in Main Types of Primary Gastric Carcinomas and Lymph Node Metastasis.
Stomach Neoplasms
Inhibitory effect of siRNA-Annexin A7 on growth, migration, and invasion in BGC823 cells and gastric cancer xenograftsin nude mice.
Stomach Neoplasms
Intratumoral heterogeneity and inverse correlation between expression of E-cadherin and collagenase type IV in human gastric carcinomas.
Stomach Neoplasms
Invasion and metastases in gastric cancer: in vitro and in vivo models with clinical correlations.
Stomach Neoplasms
JWA suppresses tumor angiogenesis via Sp1-activated MMP-2 and its prognostic significance in human gastric cancer.
Stomach Neoplasms
LOX inhibition downregulates MMP-2 and MMP-9 in gastric cancer tissues and cells.
Stomach Neoplasms
Lymph Node Metastasis of Gastric Cancer Is Associated with the Interaction Between Poly (ADP-Ribose) Polymerase 1 and Matrix Metallopeptidase 2.
Stomach Neoplasms
Lymph node micrometastasis and its correlation with MMP-2 expression in gastric carcinoma.
Stomach Neoplasms
Matrix metalloproteinase 2 (MMP-2) and their tissue inhibitor 2 (TIMP-2) in gastric cancer patients.
Stomach Neoplasms
Matrix metalloproteinase-2 is a consistent prognostic factor in gastric cancer.
Stomach Neoplasms
Melanoma differentiation-associated gene-7 suppresses human gastric cancer cell invasion and migration.
Stomach Neoplasms
MicroRNA-524-5p suppresses the growth and invasive abilities of gastric cancer cells.
Stomach Neoplasms
MMP-2 but not MMP-9 associated with COX-2 and survival in gastric cancer.
Stomach Neoplasms
MMP-2 together with MMP-9 overexpression correlated with lymph node metastasis and poor prognosis in early gastric carcinoma.
Stomach Neoplasms
mRNA Expression Analysis of E-Cadherin, VEGF, and MMPs in Gastric Cancer: a Pilot Study.
Stomach Neoplasms
Mutation analysis of tumor suppressor gene PTEN in patients with gastric carcinomas and its impact on PI3K/AKT pathway.
Stomach Neoplasms
Naringenin inhibited migration and invasion of glioblastoma cells through multiple mechanisms.
Stomach Neoplasms
Omental adipocytes enhance the invasiveness of gastric cancer cells by oleic acid-induced activation of the PI3K-Akt signaling pathway.
Stomach Neoplasms
Osteopontin promotes the progression of gastric cancer through the NF-?B pathway regulated by the MAPK and PI3K.
Stomach Neoplasms
p21-activated protein kinase 1 induces the invasion of gastric cancer cells through c-Jun NH2-terminal kinase-mediated activation of matrix metalloproteinase-2.
Stomach Neoplasms
Phenethyl isothiocyanate inhibits migration and invasion of human gastric cancer AGS cells through suppressing MAPK and NF-kappaB signal pathways.
Stomach Neoplasms
Polypeptide N-acetylgalactosaminyltransferase 2 regulates cellular metastasis-associated behavior in gastric cancer.
Stomach Neoplasms
Propofol inhibits proliferation and accelerates apoptosis of human gastric cancer cells by regulation of microRNA-451 and MMP-2 expression.
Stomach Neoplasms
Propranolol suppresses gastric cancer cell growth by regulating proliferation and apoptosis.
Stomach Neoplasms
PTEN Gene Induces Cell Invasion and Migration via Regulating AKT/GSK-3?/?-Catenin Signaling Pathway in Human Gastric Cancer.
Stomach Neoplasms
Reduced angiogenesis in peritoneal dissemination of gastric cancer through gelatinase inhibition.
Stomach Neoplasms
Reduced expression of tissue inhibitor of metalloproteinase in nodal metastasis of stomach cancer.
Stomach Neoplasms
Regulation of disease-progression genes in human gastric carcinoma cells by interleukin 8.
Stomach Neoplasms
Regulation of MMP-2 expression and activity by ?-1,3-N-acetylglucosaminyltransferase-8 in AGS gastric cancer cells.
Stomach Neoplasms
Relationship between matrix metalloproteinase-2 mRNA expression and clinicopathological and urokinase-type plasminogen activator system parameters and prognosis in human gastric cancer.
Stomach Neoplasms
Relationship between single-nucleotide polymorphism of matrix metalloproteinase-2 gene and colorectal cancer and gastric cancer susceptibility: a meta-analysis.
Stomach Neoplasms
Secretory leukocyte protease inhibitor is associated with MMP-2 and MMP-9 to promote migration and invasion in SNU638 gastric cancer cells.
Stomach Neoplasms
Serum levels of matrix metalloproteinase-2 and -9 and conventional tumor markers (CEA and CA 19-9) in patients with colorectal and gastric cancers.
Stomach Neoplasms
Signaling components involved in Bcl-w-induced migration of gastric cancer cells.
Stomach Neoplasms
Silibinin inhibits the migration and invasion of human gastric cancer SGC7901 cells by downregulating MMP-2 and MMP-9 expression via the p38MAPK signaling pathway.
Stomach Neoplasms
Similarities of in situ mRNA expression between gelatinase A (MMP-2) and type I procollagen in human gastrointestinal carcinoma: comparison with granulation tissue reaction.
Stomach Neoplasms
SPARC is associated with gastric cancer progression and poor survival of patients.
Stomach Neoplasms
Specificity Protein 1 Expression Contributes to Bcl-w-Induced Aggressiveness in Glioblastoma Multiforme.
Stomach Neoplasms
Stomach Cancer: Interconnection between the Redox State, Activity of MMP-2, MMP-9 and Stage of Tumor Growth.
Stomach Neoplasms
Study of the Relationship between MMP-2 and MMP-9 and Her2/neu Overexpression in Gastric Cancer: Clinico- Pathological Correlations.
Stomach Neoplasms
Synergistic Beneficial Effect of Docosahexaenoic Acid (DHA) and Docetaxel on the Expression Level of Matrix Metalloproteinase-2 (MMP-2) and MicroRNA-106b in Gastric Cancer.
Stomach Neoplasms
The anti-alcohol dependency drug disulfiram inhibits the viability and progression of gastric cancer cells by regulating the Wnt and NF-?B pathways.
Stomach Neoplasms
The collagenase activities, interstitial collagenase and type IV collagenase, in human stomach cancer: with special reference to local spreading and lymph node metastasis.
Stomach Neoplasms
The prognostic role of matrix metalloproteinase 2 in gastric cancer: a systematic review with meta-analysis.
Stomach Neoplasms
The significance of MMP-1 and MMP-2 in peritoneal disseminated metastasis of gastric cancer.
Stomach Neoplasms
Tissue inhibitor of metalloproteinase-2 G-418C polymorphism is associated with an increased risk of gastric cancer in a Chinese population.
Stomach Neoplasms
Tranilast (N-3,4-dimethoxycinamoyl anthranilic acid): a novel inhibitor of invasion-stimulating interaction between gastric cancer cells and orthotopic fibroblasts.
Stomach Neoplasms
Tumor-associated proteases and inhibitors in gastric cancer: analysis of prognostic impact and individual risk protease patterns.
Stomach Neoplasms
ZBTB20 promotes cell migration and invasion of gastric cancer by inhibiting I?B? to induce NF-?B activation.
Stomach Neoplasms
ZNF139 promotes tumor metastasis by increasing migration and invasion in human gastric cancer cells.
Stomach Neoplasms
[Association of functional polymorphisms in matrix metalloproteinase-2 (MMP-2) and MMP-9 genes with risk of gastric cancer in a Chinese population.]
Stomach Neoplasms
[Comparative study of mRNA expression of E-cadherin and collagenase IV in early and advanced cancers]
Stomach Neoplasms
[Effect of tumor-associated macrophages on invasion and metastasis of gastric cancer cells].
Stomach Neoplasms
[Effects of dihydromyricetin on the migration and invasion of human gastric cancer MKN45 cells and its mechanism].
Stomach Neoplasms
[Effects of FRZB on growth and metastasis of gastric cancer cell line SGC-7901]
Stomach Neoplasms
[Expression of LOX and MMP-2 in gastric cancer tissue and the effects of LOX and MMP-2 on tumor invasion and metastasis].
Stomach Neoplasms
[Inhibition of human gastric cancer metastasis by ocreotide in vitro and in vivo]
Stomach Neoplasms
[The relation between integrin, type IV collagenase and extracellular matrix in invasion and metastasis of gastric carcinoma]
Stomach Ulcer
Curcumin regulates expression and activity of matrix metalloproteinases 9 and 2 during prevention and healing of indomethacin-induced gastric ulcer.
Stomach Ulcer
Doxycycline blocks gastric ulcer by regulating matrix metalloproteinase-2 activity and oxidative stress.
Stomach Ulcer
Effect of anthocyanins on expression of matrix metalloproteinase-2 in naproxen-induced gastric ulcers.
Stomach Ulcer
Effect of melatonin on secreted and induced matrix metalloproteinase-9 and -2 activity during prevention of indomethacin-induced gastric ulcer.
Stomach Ulcer
Matrix metalloproteinase-9 activity and expression is reduced by melatonin during prevention of ethanol-induced gastric ulcer in mice.
Stomach Ulcer
Melatonin promotes angiogenesis during protection and healing of indomethacin-induced gastric ulcer: role of matrix metaloproteinase-2.
Stomach Ulcer
Spatial and temporal pattern of expression of interstitial collagenase, stromelysin/transin, gelatinase A, and TIMP-1 during experimental gastric ulcer healing.
Stomach Ulcer
The essential oil from Baccharis trimera (Less.) DC improves gastric ulcer healing in rats through modulation of VEGF and MMP-2 activity.
Stomach Ulcer
[Role of Allelic Genes of Matrix Metalloproteinases and Their Tissue Inhibitors in the Peptic Ulcer Disease Development].
Stroke
A rapid and highly sensitive strain-effect graphene-based bio-sensor for the detection of stroke and cancer bio-markers.
Stroke
Cardiac dysfunction in an animal model of neonatal asphyxia is associated with increased degradation of MLC1 by MMP-2.
Stroke
Cardiac function, myocardial glutathione, and matrix metalloproteinase-2 levels in hypoxic newborn pigs reoxygenated by 21%, 50%, or 100% oxygen.
Stroke
Complexity in differentiating truncated or matured forms of MMP-2 and MMP-9 by zymography in acute ischemic stroke induced rat brain tissues.
Stroke
Decreased plasma decorin levels following acute ischemic stroke: correlation with MMP-2 and differential expression in TOAST subtypes.
Stroke
Delayed Gelatinase Inhibition Induces Reticulon 4 Receptor Expression in the Peri-Infarct Cortex.
Stroke
Effect of neutrophil depletion on gelatinase expression, edema formation and hemorrhagic transformation after focal ischemic stroke.
Stroke
Engineering autoactivating forms of matrix metalloproteinase-9 and expression of the active enzyme in cultured cells and transgenic mouse brain.
Stroke
Gelatinase activity imaged by activatable cell-penetrating peptides in cell-based and in vivo models of stroke.
Stroke
Hyperthermia up-regulates matrix metalloproteinases and accelerates basement membrane degradation in experimental stroke.
Stroke
Identification of novel blood biomarker panels to detect ischemic stroke in patients and their responsiveness to therapeutic intervention.
Stroke
Increase in plasma matrix metalloproteinase-9 in acute stroke patients with thrombolysis failure.
Stroke
Inhibition of HIF-1? Reduced Blood Brain Barrier Damage by Regulating MMP-2 and VEGF During Acute Cerebral Ischemia.
Stroke
Inhibition of MMP-9 by a selective gelatinase inhibitor protects neurovasculature from embolic focal cerebral ischemia.
Stroke
Intra-arterial bone marrow mononuclear cell transplantation correlates with GM-CSF, PDGF-BB, and MMP-2 serum levels in stroke patients: results from a clinical trial.
Stroke
Intranuclear matrix metalloproteinases promote DNA damage and apoptosis induced by oxygen-glucose deprivation in neurons.
Stroke
Matrix metalloproteinase and cytokine profiles in monocytes over the course of stroke.
Stroke
Matrix metalloproteinase-2 gene polymorphisms are associated with ischemic stroke in a Hainan population.
Stroke
Matrix metalloproteinase-9 pretreatment level predicts intracranial hemorrhagic complications after thrombolysis in human stroke.
Stroke
Matrix Metalloproteinases Are Associated With Increased Blood-Brain Barrier Opening in Vascular Cognitive Impairment.
Stroke
Methylation in the matrix metalloproteinase-2 gene is associated with cerebral ischemic stroke.
Stroke
MMP-2 concentrations in stroke according to etiology: Adjusting for enzyme degradation in stored deep-frozen serum and other methodological pitfalls.
Stroke
MMP-9-positive neutrophil infiltration is associated to blood-brain barrier breakdown and basal lamina type IV collagen degradation during hemorrhagic transformation after human ischemic stroke.
Stroke
Optical Interference-Free Surface-Enhanced Raman Scattering CO-Nanotags for Logical Multiplex Detection of Vascular Disease-Related Biomarkers.
Stroke
Reduced brain edema and matrix metalloproteinase (MMP) expression by pre-reperfusion infusion into ischemic territory in rat.
Stroke
Reduction in levels of matrix metalloproteinases and increased expression of tissue inhibitor of metalloproteinase-2 in response to mild hypothermia therapy in experimental stroke.
Stroke
Role of NADPH Oxidase-Induced Hypoxia-Induced Factor-1? Increase in Blood-Brain Barrier Disruption after 2-Hour Focal Ischemic Stroke in Rat.
Stroke
Selective gelatinase inhibitor neuroprotective agents cross the blood-brain barrier.
Stroke
Serum activity of matrix metalloproteinase-2 and -9 is increased in chronic post-stroke individuals: a cross-sectional exploratory study.
Stroke
Sonographic monitoring of mass effect in stroke patients treated with hypothermia. Correlation with intracranial pressure and matrix metalloproteinase 2 and 9 expression.
Stroke
Therapeutic Target and Cell-signal Communication of Chlorpromazine and Promethazine in Attenuating Blood-Brain Barrier Disruption after Ischemic Stroke.
Stroke
Up-regulation of brain cytokines and metalloproteinases 1 and 2 contributes to neurological deficit and brain damage in transient ischemic stroke.
Stroke
Variants of the Matrix Metalloproteinase-2 but not the Matrix Metalloproteinase-9 genes significantly influence functional outcome after stroke.
Stroke
White matter damage is associated with matrix metalloproteinases in vascular dementia.
Stroke, Lacunar
Different roles of matrix metalloproteinases-2 and -9 after human ischaemic stroke.
Stroke, Lacunar
Selective localization of gelatinase A, an enzyme degrading beta-amyloid protein, in white matter microglia and in Schwann cells.
Subacute Sclerosing Panencephalitis
Response of extracellular matrix regulators in mouse lung after exposure to photons, protons and simulated solar particle event protons.
Subarachnoid Hemorrhage
MMP-2 and MMP-9 levels in peripheral blood after subarachnoid hemorrhage.
Subarachnoid Hemorrhage
Selective gelatinase inhibitor neuroprotective agents cross the blood-brain barrier.
Subarachnoid Hemorrhage
[Role of acute alcohol poisoning and craniocerebral trauma in the mechanism of death caused by subarachnoid hemorrhage].
Subdural Effusion
[Role of matrix metalloproteinase in transformation of subdural effusion into chronic subdural hematoma]
Supranuclear Palsy, Progressive
Selective localization of gelatinase A, an enzyme degrading beta-amyloid protein, in white matter microglia and in Schwann cells.
Sweet Syndrome
Inflammatory cells, cytokines and matrix metalloproteinases in amicrobial pustulosis of the folds and other neutrophilic dermatoses.
Sweet Syndrome
Role of inflammatory cells, cytokines and matrix metalloproteinases in neutrophil-mediated skin diseases.
Synovitis
Active synovial matrix metalloproteinase-2 is associated with radiographic erosions in patients with early synovitis.
Synovitis
Cadherin-11 involves in synovitis and increases the migratory and invasive capacity of fibroblast-like synoviocytes of osteoarthritis.
Synovitis
Changes in MMP-2 and -9 activity and MMP-8 reactivity after amphotericin B induced synovitis and treatment with bufexamac.
Synovitis
Quercetin: a potential natural drug for adjuvant treatment of rheumatoid arthritis.
Takayasu Arteritis
Serum MMP-2 and MMP-9 in patients with Behçet's disease: Do their higher levels correlate to vasculo-Behçet's disease associated with aneurysm formation?
Temporomandibular Joint Disorders
Correlation of molecular biomarker concentrations between synovial fluid and saliva of the patients with temporomandibular disorders.
Temporomandibular Joint Disorders
Is the incidence of temporomandibular disorder increased in polycystic ovary syndrome?
Temporomandibular Joint Disorders
MMPs in tissues retrieved during surgery from patients with TMJ disorders relate to pain more than to radiological damage score.
Tendinopathy
Additional evidence supports association of common genetic variants in MMP3 and TIMP2 with increased risk of chronic Achilles tendinopathy susceptibility.
Tenosynovitis
Production of cytokines, vascular endothelial growth factor, matrix metalloproteinases, and tissue inhibitor of metalloproteinases 1 by tenosynovium demonstrates its potential for tendon destruction in rheumatoid arthritis.
Teratocarcinoma
Imbalance of MMP-2 and MMP-9 expression versus TIMP-1 and TIMP-2 reflects increased invasiveness of human testicular germ cell tumours.
Testicular Neoplasms
Imbalance of MMP-2 and MMP-9 expression versus TIMP-1 and TIMP-2 reflects increased invasiveness of human testicular germ cell tumours.
Testicular Neoplasms
Inhibitory effects of a nutrient mixture on human testicular cancer cell line NT 2/DT matrigel invasion and MMP activity.
Testicular Neoplasms
Nuclear Localization of PTTG1 Promotes Migration and Invasion of Seminoma Tumor through Activation of MMP-2.
Thrombocytopenia
Inhaled nitric oxide inhibits the release of matrix metalloproteinase-2, but not platelet activation, during extracorporeal membrane oxygenation in adult rabbits.
Thrombocytosis
Importance of plasma matrix metalloproteinases (MMP) and tissue inhibitors of metalloproteinase (TIMP) in development of fibrosis in agnogenic myeloid metaplasia.
Thrombosis
A novel mechanism regulating human platelet activation by MMP-2-mediated PAR1 biased signaling.
Thrombosis
Contribution of the TNF-? (Tumor Necrosis Factor-?)-TNF-Rp55 (Tumor Necrosis Factor Receptor p55) Axis in the Resolution of Venous Thrombus.
Thrombosis
Deep vein thrombosis resolution is modulated by monocyte CXCR2-mediated activity in a mouse model.
Thrombosis
Difference in matrix-degrading protease expression and activity between thrombus-free and thrombus-covered wall of abdominal aortic aneurysm.
Thrombosis
Differential transcriptional activation of matrix metalloproteinase-2 and membrane type-1 matrix metalloproteinase by experimental deep venous thrombosis and thrombin.
Thrombosis
Expression changes and roles of matrix metalloproteinases in a rat model of traumatic deep vein thrombosis.
Thrombosis
Granulocytes in coronary thrombus evolution after myocardial infarction - time-dependent changes in expression of matrix metalloproteinases.
Thrombosis
Higher levels of plasma matrix metalloproteinase-2 are associated with a significantly increased risk of arterial thrombosis in patients with the antiphospholipid syndrome.
Thrombosis
Homocysteine-Enhanced Proteolytic and Fibrinolytic Processes in Thin Intraluminal Thrombus and Adjacent Wall of Abdominal Aortic Aneurysm: Study In Vitro.
Thrombosis
Immunohistochemical detection of MMP-2 and MMP-9 in a stasis-induced deep vein thrombosis model and its application to thrombus age estimation.
Thrombosis
Increased expression of 72-kd type IV collagenase (MMP-2) in human aortic atherosclerotic lesions.
Thrombosis
Involvement of the mural thrombus as a site of protease release and activation in human aortic aneurysms.
Thrombosis
Losartan and captopril treatment rescue normal thrombus formation in microfibril associated glycoprotein-1 (MAGP1) deficient mice.
Thrombosis
Loss of matrix metalloproteinase 2 in platelets reduces arterial thrombosis in vivo.
Thrombosis
Matrix metalloproteinase-2 enhances platelet deposition on collagen under flow conditions.
Thrombosis
Membrane-type matrix metalloproteinase-mediated angiogenesis in a fibrin-collagen matrix.
Thrombosis
MR imaging of iron phagocytosis in intraluminal thrombi of abdominal aortic aneurysms in humans.
Thrombosis
Myeloid p53 regulates macrophage polarization and venous thrombus resolution by inflammatory vascular remodeling in mice.
Thrombosis
Overexpression of transforming growth factor-beta1 stabilizes already-formed aortic aneurysms: a first approach to induction of functional healing by endovascular gene therapy.
Thrombosis
Plasmin inhibition increases MMP-9 activity and decreases vein wall stiffness during venous thrombosis resolution.
Thrombosis
Platelet-Associated Matrix Metalloproteinases Regulate Thrombus Formation and Exert Local Collagenolytic Activity.
Thrombosis
Resistin Promotes Thrombosis in Rats with Deep Vein Thrombosis via Up-Regulating MMP-2, MMP-9, and PAI-1.
Thrombosis
Spatial differences of matrix metalloproteinase-2 and matrix metalloproteinase-9 within abdominal aortic aneurysm wall and intraluminal thrombus.
Thrombosis
Up-regulation of matrix metalloproteinase-2 and membrane-type 1-matrix metalloproteinase were coupled with that of type I procollagen in granulation tissue response after the onset of aortic dissection.
Thrombosis
Vein wall remodeling after deep vein thrombosis involves matrix metalloproteinases and late fibrosis in a mouse model.
Thrombotic Microangiopathies
Loss of diacylglycerol kinase ? causes thrombotic microangiopathy by impairing endothelial VEGFA signaling.
Thymoma
Activation of matrix metalloproteinase-2 is correlated with invasiveness in thymic epithelial tumors.
Thymoma
Activation ratio of MMP-2 and expression of MT1-MMP are correlated in thymic epithelial tumours.
Thymoma
Cetyltrimethylammonium Bromide Suppresses the Migration and Invasion of Hepatic Mahlavu Cells by Modulating Fibroblast Growth Factor Signaling.
Thymoma
Expression of matrix metalloproteinases 2 and 7 in tumor cells correlates with the World Health Organization classification subtype and clinical stage of thymic epithelial tumors.
Thymoma
Increased expression of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 is correlated with poor prognostic variables in patients with thymic epithelial tumors.
Thymoma
[Correlation between MMP-2 activation and MT1-MMP mRNA expression in thymic epithelial tumors]
Thyroid Cancer, Papillary
Bone sialoprotein, matrix metalloproteinase 2, and alpha(v)beta3 integrin in osteotropic cancer cell invasion.
Thyroid Cancer, Papillary
Clinical value of matrix metalloproteinase-2 and -9 in ultrasound-guided radiofrequency ablation treatment for papillary thyroid carcinoma.
Thyroid Cancer, Papillary
Clinicopathologic evaluation of immunohistochemical CD147 and MMP-2 expression in differentiated thyroid carcinoma.
Thyroid Cancer, Papillary
Correlations between papillary thyroid cancer and peripheral blood levels of matrix metalloproteinase-2, matrix metalloproteinase-9, tissue inhibitor of metalloproteinase-1, and tissue inhibitor of metalloproteinase-2.
Thyroid Cancer, Papillary
Enhanced production and activation of progelatinase A mediated by membrane-type 1 matrix metalloproteinase in human papillary thyroid carcinomas.
Thyroid Cancer, Papillary
Estrogen receptor subtype expression and regulation is altered in papillary thyroid cancer after menopause.
Thyroid Cancer, Papillary
Expression of COX-2 is increased with age in papillary thyroid cancer.
Thyroid Cancer, Papillary
Expression of matrix metalloproteinase-2 and its tissue inhibitor-2 in fetal and neoplastic thyroid tissue and their significance as diagnostic and prognostic markers in papillary carcinoma.
Thyroid Cancer, Papillary
Expression of Receptors for Pituitary-Type Growth Hormone-Releasing Hormone (pGHRH-R) in Human Papillary Thyroid Cancer Cells: Effects of GHRH Antagonists on Matrix Metalloproteinase-2.
Thyroid Cancer, Papillary
Immunohistochemical levels of matrix metalloproteinase-2 and CD44 variant 6 protein in the diagnosis and lateral cervical lymph node metastasis of papillary thyroid carcinoma.
Thyroid Cancer, Papillary
Increased expression of matrix metalloproteinase-2: a diagnostic marker but not prognostic marker of papillary thyroid carcinoma.
Thyroid Cancer, Papillary
Protein expression of matrix metalloproteinases 2 and 9 and tissue inhibitors of metalloproteinase 1 and 2 in papillary thyroid carcinomas.
Thyroid Cancer, Papillary
Relationship between protein expression of VEGF-C, MMP-2 and lymph node metastasis in papillary thyroid cancer.
Thyroid Cancer, Papillary
Serum MMP-2 as a potential predictive marker for papillary thyroid carcinoma.
Thyroid Cancer, Papillary
Single nucleotide polymorphisms in matrix metalloproteinase 2 (MMP2) enhance BRAFV600E mutation-mediated oncogenicity and invasiveness of papillary thyroid cancer cells.
Thyroid Cancer, Papillary
The Synergistic Effects of Celecoxib and Sodium Valproate on Apoptosis and Invasiveness Behavior of Papillary Thyroid Cancer Cell Line In-vitro.
Thyroid Cancer, Papillary
[Correlations of serous levels of matrix metalloproteinases (MMP-2 and MMP-9) to invasion and metastasis of papillary thyroid carcinoma]
Thyroid Cancer, Papillary
[Expression of matrix metalloproteinases 2 and 9 and their tissue inhibitors 1 and 2 in papillary thyroid cancer: an association with the clinical, morphological and ultrastructural characteristics of a tumor].
Thyroid Diseases
MMP-2, MMP-9, TIMP-1, and TIMP-2 in the Peripheral Blood of Patients with Differentiated Thyroid Carcinoma.
Thyroid Neoplasms
Clinicopathologic evaluation of immunohistochemical CD147 and MMP-2 expression in differentiated thyroid carcinoma.
Thyroid Neoplasms
Comparative analysis of protein expression in differentiated thyroid tumours: a multicentre study.
Thyroid Neoplasms
Concentration of metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in the serum of patients with benign and malignant thyroid tumours treated surgically.
Thyroid Neoplasms
Distribution of the 72-kd type IV collagenase in nonneoplastic and neoplastic thyroid tissue.
Thyroid Neoplasms
Down-regulation of matrix metalloproteinase-7 inhibits metastasis of human anaplastic thyroid cancer cell line.
Thyroid Neoplasms
Enigma Plays Roles in Survival of Thyroid Carcinoma Cells through PI3K/AKT Signaling and Survivin.
Thyroid Neoplasms
Estrogen induced metastatic modulators MMP-2 and MMP-9 are targets of 3,3'-diindolylmethane in thyroid cancer.
Thyroid Neoplasms
Expression and role of matrix metalloproteinases MMP-2 and MMP-9 in human spinal column tumors.
Thyroid Neoplasms
Expression of matrix metalloproteinase 2 (MMP-2) and tissue inhibitor of metalloproteinase 2 (TIMP-2) in medullary thyroid carcinoma: prognostic implications.
Thyroid Neoplasms
Expression of matrix metalloproteinase-2 and its tissue inhibitor-2 in fetal and neoplastic thyroid tissue and their significance as diagnostic and prognostic markers in papillary carcinoma.
Thyroid Neoplasms
Ginsenoside Rg3 Inhibition of Thyroid Cancer Metastasis Is Associated with Alternation of Actin Skeleton.
Thyroid Neoplasms
Increased expression of matrix metalloproteinase-2: a diagnostic marker but not prognostic marker of papillary thyroid carcinoma.
Thyroid Neoplasms
Increased plasminogen activator and type IV collagenase activity in invasive follicular thyroid carcinoma cells.
Thyroid Neoplasms
Long non-coding RNA LIFR-AS1 regulates the proliferation, migration and invasion of human thyroid cancer cells.
Thyroid Neoplasms
Matrix metalloproteinases, tissue inhibitors of matrix metalloproteinases and angiogenic cytokines in peripheral blood of patients with thyroid cancer.
Thyroid Neoplasms
MMP-2, MMP-9, TIMP-1, and TIMP-2 in the Peripheral Blood of Patients with Differentiated Thyroid Carcinoma.
Thyroid Neoplasms
mRNA levels of membrane-type 1 matrix metalloproteinase (MT1-MMP), MMP-2, and MMP-9 and of their inhibitors TIMP-2 and TIMP-3 in normal thyrocytes and thyroid carcinoma cell lines.
Thyroid Neoplasms
PLK1 gene suppresses cell invasion of undifferentiated thyroid carcinoma through the inhibition of CD44v6, MMP-2 and MMP-9.
Thyroid Neoplasms
Reduced tissue inhibitor of metalloproteinase-2 expression is associated with advanced medullary thyroid carcinoma.
Thyroid Neoplasms
Relationship between protein expression of VEGF-C, MMP-2 and lymph node metastasis in papillary thyroid cancer.
Thyroid Neoplasms
Shikonin Inhibits Thyroid Cancer Cell Growth and Invasiveness through Targeting Major Signaling Pathways.
Thyroid Neoplasms
Sulforaphane inhibits thyroid cancer cell growth and invasiveness through the reactive oxygen species-dependent pathway.
Thyroid Neoplasms
Synergistic cytotoxicity of the dipeptidyl peptidase-IV inhibitor gemigliptin with metformin in thyroid carcinoma cells.
Thyroid Neoplasms
TGF-?1 induces HMGA1 expression: The role of HMGA1 in thyroid cancer proliferation and invasion.
Thyroid Neoplasms
Type IV collagen, type IV collagenase activity and ability of cell proliferation in human thyroid tumours.
Thyroid Neoplasms
[Effect of Nifuroxazide on Proliferation, Migration, and Invasion of Thyroid Papillary Carcinoma Cells].
Thyroid Nodule
Ratio of metalloproteinase 2 to tissue inhibitor of metalloproteinase 2 in medullary thyroid carcinoma.
Thyrotoxicosis
Effects of radioiodine administration on serum concentrations of matrix metalloproteinases, adiponectin and thrombospondin-1.
Tongue Neoplasms
Emodin, aloe-emodin and rhein inhibit migration and invasion in human tongue cancer SCC-4 cells through the inhibition of gene expression of matrix metalloproteinase-9.
Tongue Neoplasms
MMP-1/2 and TIMP-1/2 expression levels, and the levels of collagenous and elastic fibers correlate with disease progression in a hamster model of tongue cancer.
Tongue Neoplasms
Prognostic significance of matrix metalloproteinase-2, -8, -9, and -13 in oral tongue cancer.
Tooth Mobility
Oxymatrine alleviates periodontitis in rats by inhibiting inflammatory factor secretion and regulating MMPs/TIMP protein expression1.
Toxocariasis
Matrix metalloproteinase-2 and matrix metalloproteinase-9 in mice with ocular toxocariasis.
Toxoplasmosis
Matrix metalloproteinase-2 and -9 lead to fibronectin degradation in astroglia infected with Toxoplasma gondii.
Toxoplasmosis
Up-regulation of matrix metalloproteinases-2 and -9 via an Erk1/2/NF-?B pathway in murine mast cells infected with Toxoplasma gondii.
Trauma, Nervous System
Matrix metalloproteinase-2 and -9 as promising benefactors in development, plasticity and repair of the nervous system.
Triple Negative Breast Neoplasms
Brucine suppresses breast cancer metastasis via inhibiting epithelial mesenchymal transition and matrix metalloproteinases expressions.
Triple Negative Breast Neoplasms
Docosahexaenoic acid suppresses migration of triple-negative breast cancer cell through targeting metastasis-related genes and microRNA under normoxic and hypoxic conditions.
Triple Negative Breast Neoplasms
The ras homolog gene family, member A (RhoA) pathway mediates MMP-2 and MMP-9-independent invasive behavior in a triple-negative breast cancer cell line.
Trophoblastic Neoplasms
[MMP-2/TIMP-2 expression in the trophoblasts of patients with gestational trophoblastic disease]
Tuberculosis
Activity of matrix metalloproteinase 2 and 9 isoforms in sputum samples from individuals infected with M. tuberculosis.
Tuberculosis
l-Glutamate in Middlebrook 7H9 culture medium upregulates matrix metalloproteinase-2 secretion from human astrocytoma cells.
Tuberculosis
Mycobacterium tuberculosis-infected human monocytes down-regulate microglial MMP-2 secretion in CNS tuberculosis via TNF?, NF?B, p38 and caspase 8 dependent pathways.
Tuberculosis
[Clinical significance of detecting VEGF, CD44v6, MMP-2, and MMP-9 in malignant ascites]
Tuberculosis, Meningeal
Elevated Matrix Metalloproteinase Concentrations Offer Novel Insight Into Their Role in Pediatric Tuberculous Meningitis.
Tuberculosis, Meningeal
Marked increase of matrix metalloproteinase 9 in cerebrospinal fluid of patients with fungal or tuberculous meningoencephalitis.
Tuberculosis, Meningeal
Persistent increase of matrix metalloproteinases in cerebrospinal fluid of tuberculous meningitis.
Tuberous Sclerosis
TGF-beta enhances MMP-2 expression and activity through AKT in fibroblasts derived from angiofibromas in patients with tuberous sclerosis complex.
type i protein arginine methyltransferase deficiency
PRMT1 is a novel molecular therapeutic target for clear cell renal cell carcinoma.
Uremia
Alterations in peripheral blood levels of TIMP-1, MMP-2, and MMP-9 in patients with type-2 diabetes.
Uremia
Association of Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9 With Endothelial Dysfunction, Cardiovascular Disease Risk Factors and thrombotic events in Children With End-stage Renal Disease.
Uremia
Peripheral blood level alterations of MMP-2 and MMP-9 in patients with chronic kidney disease on conservative treatment and on hemodialysis.
Uremia
Plasma and Aorta Biochemistry and MMPs Activities in Female Rabbit Fed Methionine Enriched Diet and Their Offspring.
Uremia
The serum levels of MMP-9, MMP-2 and vWF in patients with low doses of urokinase peritoneal dialysis decreased uremia complicated with cerebral infarction.
Ureteral Obstruction
Effect of ureteral obstruction on matrix metalloproteinase-2 in rat renal cortex.
Ureteral Obstruction
Influence of dietary iron intake restriction on the development of hypertension in weanling prehypertensive rats.
Ureteral Obstruction
Integrating Polydopamine Nanosphere/Aptamers Nanoplatform with DNase-I-assisted Recycling Amplification Strategy for Simultaneous Detection of MMP-9 and MMP-2 During Renal Interstitial Fibrosis.
Ureteral Obstruction
Involvement of matrix metalloproteinase-2 in the development of renal interstitial fibrosis in mouse obstructive nephropathy.
Ureteral Obstruction
Matrix Metalloproteinase-2 Knockout and Heterozygote Mice Are Protected from Hydronephrosis and Kidney Fibrosis after Unilateral Ureteral Obstruction.
Ureteral Obstruction
MMP-2 inhibition reduces renal macrophage infiltration with increased fibrosis in UUO.
Urinary Bladder Neoplasms
4-HPR impairs bladder cancer cell migration and invasion by interfering with the Wnt5a/JNK and Wnt5a/MMP-2 signaling pathways.
Urinary Bladder Neoplasms
A novel approach to using matrix metalloproteinases for bladder cancer.
Urinary Bladder Neoplasms
An inverse relationship between KAI1 expression, invasive ability, and MMP-2 expression and activity in bladder cancer cell lines.
Urinary Bladder Neoplasms
Analysis of the gene expression of SPARC and its prognostic value for bladder cancer.
Urinary Bladder Neoplasms
Association of MMP-2, RB and PAI-1 with decreased recurrence-free survival and overall survival in bladder cancer patients.
Urinary Bladder Neoplasms
Association of single nucleotide polymorphisms in promoter of matrix metalloproteinase-2, 8 genes with bladder cancer risk in Northern India.
Urinary Bladder Neoplasms
Attenuation of chloroquine and hydroxychloroquine on the invasive potential of bladder cancer through targeting matrix metalloproteinase 2 expression.
Urinary Bladder Neoplasms
Bacillus Calmette-Guérin enhances production and secretion of type IV collagenases in peripheral blood mononuclear cells.
Urinary Bladder Neoplasms
Capsaicin attenuates cell migration via SIRT1 targeting and inhibition to enhance cortactin and ?-catenin acetylation in bladder cancer cells.
Urinary Bladder Neoplasms
Comment to: "Detection and Molecular Staging of Bladder Cancer Using Real-Time RT-PCR for Gelatinases MMP-2, MMP-9 and TIMP-2 in Peripheral Blood"
Urinary Bladder Neoplasms
Detection and Molecular Staging of Bladder Cancer Using Real-Time RT-PCR for Gelatinases (MMP-2, MMP-9) and TIMP-2 in Peripheral Blood.
Urinary Bladder Neoplasms
Detection of tumor-associated antigens in culture supernatants using autoantibodies in sera from patients with bladder cancer.
Urinary Bladder Neoplasms
Diagnostic evaluation of apoptosis inhibitory gene and tissue inhibitor matrix metalloproteinase-2 in patients with bladder cancer.
Urinary Bladder Neoplasms
Divergent behaviors and underlying mechanisms of cell migration and invasion in non-metastatic T24 and its metastatic derivative T24T bladder cancer cell lines.
Urinary Bladder Neoplasms
Editorial: MMP-2 and MMP-9 in lymph-node-positive bladder cancer.
Urinary Bladder Neoplasms
Effect of TRPV2 cation channels on the proliferation, migration and invasion of 5637 bladder cancer cells.
Urinary Bladder Neoplasms
Effects of tumor necrosis factor-alpha and interferon-gamma on expressions of matrix metalloproteinase-2 and -9 in human bladder cancer cells.
Urinary Bladder Neoplasms
Enhanced urinary gelatinase activities (matrix metalloproteinases 2 and 9) are associated with early-stage bladder carcinoma: a comparison with clinically used tumor markers.
Urinary Bladder Neoplasms
Evaluation of MMP-2, MMP-9, TIMP-1, TIMP-2, NGAL and MMP-9/NGAL complex in urine and sera from patients with bladder cancer.
Urinary Bladder Neoplasms
Excretion of matrix metalloproteinases 2 and 9 in urine is associated with a high stage and grade of bladder carcinoma.
Urinary Bladder Neoplasms
Extra virgin olive oil phenols suppress migration and invasion of T24 human bladder cancer cells through modulation of matrix metalloproteinase-2.
Urinary Bladder Neoplasms
Gelatin-modified gold nanoparticles for direct detection of urinary total gelatinase activity: Diagnostic value in bladder cancer.
Urinary Bladder Neoplasms
High levels of tissue inhibitor of metalloproteinase-2 (TIMP-2) expression are associated with poor outcome in invasive bladder cancer.
Urinary Bladder Neoplasms
High VEGF-D and Low MMP-2 Serum Levels Predict Nodal-Positive Disease in Invasive Bladder Cancer.
Urinary Bladder Neoplasms
In situ gelatinolytic activity correlates with tumor progression and prognosis in patients with bladder cancer.
Urinary Bladder Neoplasms
Introduction of insulin-like growth factor binding protein-2 gene into human bladder cancer cells enhances their metastatic potential.
Urinary Bladder Neoplasms
Isorhapontigenin (ISO) Inhibits Invasive Bladder Cancer Formation In Vivo and Human Bladder Cancer Invasion In Vitro by Targeting STAT1/FOXO1 Axis.
Urinary Bladder Neoplasms
Loss of GATA3 in bladder cancer promotes cell migration and invasion.
Urinary Bladder Neoplasms
Low Circulating Levels of ProMMP-2 Are Associated with Adverse Prognosis in Bladder Cancer.
Urinary Bladder Neoplasms
Matrix metalloproteinase-2 immunoreactive protein as a prognostic marker in bladder cancer.
Urinary Bladder Neoplasms
Matrix metalloproteinases (MMPs) in bladder cancer: the induction of MMP9 by epidermal growth factor and its detection in urine.
Urinary Bladder Neoplasms
MicroRNA-106a suppresses proliferation, migration, and invasion of bladder cancer cells by modulating MAPK signaling, cell cycle regulators, and Ets-1-mediated MMP-2 expression.
Urinary Bladder Neoplasms
MicroRNA-20b inhibits the proliferation, migration and invasion of bladder cancer EJ cells via the targeting of cell cycle regulation and Sp-1-mediated MMP-2 expression.
Urinary Bladder Neoplasms
MiR-221-induced PUMA silencing mediates immune evasion of bladder cancer cells.
Urinary Bladder Neoplasms
MiRNA-141 and miRNA-200b are closely related to invasive ability and considered as decision-making biomarkers for the extent of PLND during cystectomy.
Urinary Bladder Neoplasms
MMP-2 and MMP-9 as prognostic markers for the early detection of urinary bladder cancer.
Urinary Bladder Neoplasms
Noninvasive Diagnosis of Bladder Cancer by Detection of Matrix Metalloproteinases (MMP-2 and MMP-9) and Their Inhibitor (TIMP-2) in Urine.
Urinary Bladder Neoplasms
p38 mitogen-activated protein kinase-driven MAPKAPK2 regulates invasion of bladder cancer by modulation of MMP-2 and MMP-9 activity.
Urinary Bladder Neoplasms
p85? Inactivates MMP-2 and Suppresses Bladder Cancer Invasion by Inhibiting MMP-14 Transcription and TIMP-2 Degradation.
Urinary Bladder Neoplasms
Phosphorylated hepatocyte growth factor receptor/c-Met is associated with tumor growth and prognosis in patients with bladder cancer: correlation with matrix metalloproteinase-2 and -7 and E-cadherin.
Urinary Bladder Neoplasms
Positive Correlation between Matrix Metalloproteinases and Epithelial-to-Mesenchymal Transition and its Association with Clinical Outcome in Bladder Cancer Patients.
Urinary Bladder Neoplasms
Profiling of matrix metalloproteinases and tissue inhibitors of metalloproteinases proteins in bladder urothelial carcinoma.
Urinary Bladder Neoplasms
Prognostic value of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in bladder carcinoma.
Urinary Bladder Neoplasms
Prognostic value of membrane type 1 and 2 matrix metalloproteinase expression and gelatinase A activity in bladder cancer.
Urinary Bladder Neoplasms
Prognostic values of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 expression in bladder cancer.
Urinary Bladder Neoplasms
Serum tissue inhibitor of metalloproteinase-2 (TIMP-2) and matrix metalloproteinase-2 in complex with the inhibitor (MMP-2:TIMP-2) as prognostic markers in bladder cancer.
Urinary Bladder Neoplasms
Silencing expression of the NANOG gene and changes in migration and metastasis of urinary bladder cancer cells.
Urinary Bladder Neoplasms
Suppressions of Migration and Invasion by Cantharidin in TSGH-8301 Human Bladder Carcinoma Cells through the Inhibitions of Matrix Metalloproteinase-2/-9 Signaling.
Urinary Bladder Neoplasms
The MMP-1, MMP-2, and MMP-9 gene polymorphisms and susceptibility to bladder cancer: a meta-analysis.
Urinary Bladder Neoplasms
The role of matrix metalloproteinases in pathogenesis of human bladder cancer.
Urinary Bladder Neoplasms
The value of combined use of survivin mRNA and matrix metalloproteinase 2 and 9 for bladder cancer detection in voided urine.
Urinary Bladder Neoplasms
Tumor progression and expression of matrix metalloproteinase-2 (MMP-2) mRNA by human urinary bladder cancer cells.
Urinary Bladder Neoplasms
Urinary gelatinase activities (matrix metalloproteinases 2 and 9) in human bladder tumors.
Urinary Bladder Neoplasms
Urinary type IV collagenase: elevated levels are associated with bladder transitional cell carcinoma.
Urinary Bladder Neoplasms
[Gene expressions of type IV collagenase and tissue inhibitor of metalloproteinases (TIMP) in human bladder cancers]
Urinary Bladder Neoplasms
[Mechanisms for effect of osthole on inhibiting the growth and invasion of bladder cancer cells].
Urinary Bladder Neoplasms
[Prospects for molecular research in urological oncology: bladder cancer]
Urinary Incontinence
Collagen metabolism and turnover in women with stress urinary incontinence and pelvic prolapse.
Urinary Incontinence
Elastin metabolism in pelvic tissues: is it modulated by reproductive hormones?
Urinary Incontinence
Expression of matrix metalloproteinase-2 and tissue inhibitors of metalloproteinase-1 (TIMP-1, TIMP-2 and TIMP-3) in women with uterine prolapse but without urinary incontinence.
Urinary Tract Infections
Diagnostic accuracy of urine neutrophil gelatinase-associated lipocalin and urine kidney injury molecule-1 as predictors of acute pyelonephritis in young children with febrile urinary tract infection.
Urinary Tract Infections
Early prediction of urinary tract infection with urinary neutrophil gelatinase associated lipocalin.
Urinary Tract Infections
Increased urinary neutrophil gelatinase associated lipocalin in urinary tract infections and leukocyturia.
Urinary Tract Infections
Increased urinary neutrophil gelatinase associated lipocalin levels in a rat model of upper urinary tract infection.
Urinary Tract Infections
Relationship between metalloproteinase-2 and -9 levels in plasma and vaginal secretion with preterm birth.
Urinary Tract Infections
Urinary Neutrophil Gelatinase Associated Lipocalin - A Sensitive Marker for Urinary Tract Infection in Children.
Urinary Tract Infections
[Virulence genes and bacteriocins in Enterococcus faecalis strains isolated from different clinical samples in Maule Region, Chile].
Uterine Cervical Neoplasms
A coumarin-based fluorescence resonance energy transfer probe targeting matrix metalloproteinase-2 for the detection of cervical cancer.
Uterine Cervical Neoplasms
A model for co-expression pattern analysis of genes implicated in angiogenesis and tumour cell invasion in cervical cancer.
Uterine Cervical Neoplasms
A novel role of metalloproteinase in cancer-mediated immunosuppression.
Uterine Cervical Neoplasms
A Study of Matrix Metalloproteinase-2 and Interleukin-18 in Preinvasive and Invasive Lesions of Cancer Cervix.
Uterine Cervical Neoplasms
AAC-11 overexpression induces invasion and protects cervical cancer cells from apoptosis.
Uterine Cervical Neoplasms
Anti-Cancer Activity of As4O6 and its Efficacy in a Series of Patient-Derived Xenografts for Human Cervical Cancer.
Uterine Cervical Neoplasms
Anti-tumor activity of staurosporine in the tumor microenvironment of cervical cancer: An in vitro study.
Uterine Cervical Neoplasms
Bisdemethoxycurcumin Suppresses Migration and Invasion of Human Cervical Cancer HeLa Cells via Inhibition of NF-?B, MMP-2 and -9 Pathways.
Uterine Cervical Neoplasms
Cell membrane-associated MT1-MMP-dependent activation of pro-MMP-2 in A375 melanoma cells.
Uterine Cervical Neoplasms
Characterization of extracellular matrix-degrading proteinase and its inhibitor in gynecologic cancer tissues with clinically different metastatic form.
Uterine Cervical Neoplasms
Chemo-preventive and therapeutic effect of the dietary flavonoid kaempferol: A comprehensive review.
Uterine Cervical Neoplasms
Clinical significance of matrix metalloproteinase-2 in cancer of uterine cervix: a semiquantitative study of immunoreactivities using tissue array.
Uterine Cervical Neoplasms
Combined delivery of salinomycin and docetaxel by dual-targeting gelatinase nanoparticles effectively inhibits cervical cancer cells and cancer stem cells.
Uterine Cervical Neoplasms
Correlation of the in situ detection of polymerase chain reaction-amplified metalloproteinase complementary DNAs and their inhibitors with prognosis in cervical carcinoma.
Uterine Cervical Neoplasms
Culture of human cervical cancer cells, SiHa, in the presence of fibronectin activates MMP-2.
Uterine Cervical Neoplasms
Diagnostic Power of Cytokine M-CSF, Metalloproteinase 2 (MMP-2) and Tissue Inhibitor-2 (TIMP-2) in Cervical Cancer Patients Based on ROC Analysis.
Uterine Cervical Neoplasms
E6/E7 oncoproteins of high risk HPV-16 upregulate MT1-MMP, MMP-2 and MMP-9 and promote the migration of cervical cancer cells.
Uterine Cervical Neoplasms
Effect of human seminal fluid on production of messenger ribonucleic acid for metalloproteinase 2 and metalloproteinase 9 in cervical epithelial carcinoma cells.
Uterine Cervical Neoplasms
Effects of Galectin-1 on Biological Behavior in Cervical Cancer.
Uterine Cervical Neoplasms
EMMPRIN-induced MMP-2 activation cascade in human cervical squamous cell carcinoma.
Uterine Cervical Neoplasms
Epidermal growth factor receptor regulates MT1-MMP and MMP-2 synthesis in SiHa cells via both PI3-K/AKT and MAPK/ERK pathways.
Uterine Cervical Neoplasms
Expression of MAPK1 in cervical cancer and effect of MAPK1 gene silencing on epithelial-mesenchymal transition, invasion and metastasis.
Uterine Cervical Neoplasms
Expression of matrix metalloproteinase-2 and 9 in cervical intraepithelial neoplasia and cervical carcinoma among different age groups of premenopausal and postmenopausal women.
Uterine Cervical Neoplasms
Extracellular matrix metalloproteinase inducer (EMMPRIN) remodels the extracellular matrix through enhancing matrix metalloproteinases (MMPs) and inhibiting tissue inhibitors of MMPs expression in HPV-positive cervical cancer cells.
Uterine Cervical Neoplasms
FOXM1 promotes tumor cell invasion and correlates with poor prognosis in early-stage cervical cancer.
Uterine Cervical Neoplasms
Genetic polymorphisms in MMP 2, 3, 7, and 9 genes and the susceptibility and clinical outcome of cervical cancer in a Chinese Han population.
Uterine Cervical Neoplasms
HPV16 Oncoproteins Promote Cervical Cancer Invasiveness by Upregulating Specific Matrix Metalloproteinases.
Uterine Cervical Neoplasms
Human nonmetastatic clone 23 type 1 gene suppresses migration of cervical cancer cells and enhances the migration inhibition of fungal immunomodulatory protein from Ganoderma tsugae.
Uterine Cervical Neoplasms
Immunohistochemical detection of matrix metalloproteinases (MMP) 1 and 2, and tissue inhibitor of metalloproteinase 2 (TIMP 2) in stage IB cervical cancer.
Uterine Cervical Neoplasms
In vitro modulation of MMP-2 and MMP-9 in human cervical and ovarian cancer cell lines by cytokines, inducers and inhibitors.
Uterine Cervical Neoplasms
Matrix metalloproteinase-2 (MMP-2) and its tissue inhibitor (TIMP-2) are prognostic factors in cervical cancer, related to invasive disease but not to high-risk human papillomavirus (HPV) or virus persistence after treatment of CIN.
Uterine Cervical Neoplasms
Matrix metalloproteinases-2 and -9 in cervical cancer: different roles in tumor progression.
Uterine Cervical Neoplasms
MicroRNA-106a promotes cell migration and invasion by targeting tissue inhibitor of matrix metalloproteinase 2 in cervical cancer.
Uterine Cervical Neoplasms
MicroRNA-99b suppresses human cervical cancer cell activity by inhibiting the PI3K/AKT/mTOR signaling pathway.
Uterine Cervical Neoplasms
MMP-2 and MMP-9 gene polymorphisms associated with cervical cancer risk.
Uterine Cervical Neoplasms
No Association of Matrix Metalloproteinase [MMP]-2 (-735C > T) and Tissue Inhibitor of Metalloproteinase [TIMP]-2 (-418G > C) Gene Polymorphisms with Cervical Cancer Susceptibility.
Uterine Cervical Neoplasms
Overexpression of myeloid zinc finger 1 suppresses matrix metalloproteinase-2 expression and reduces invasiveness of SiHa human cervical cancer cells.
Uterine Cervical Neoplasms
Polymorphism in the Matrix Metalloproteinase-2 Gene Promoter is Associated with Cervical Neoplasm Risk in Mexican Women.
Uterine Cervical Neoplasms
Praeruptorin A Inhibits Human Cervical Cancer Cell Growth and Invasion by Suppressing MMP-2 Expression and ERK1/2 Signaling.
Uterine Cervical Neoplasms
Predicting high-risk human papillomavirus infection, progression of cervical intraepithelial neoplasia, and prognosis of cervical cancer with a panel of 13 biomarkers tested in multivariate modeling.
Uterine Cervical Neoplasms
Relationship between expression of matrix metalloproteinase-2 and matrix metalloproteinase-9 and invasion ability of cervical cancer cells.
Uterine Cervical Neoplasms
Role of serum VEGFA, TIMP2, MMP2 and MMP9 in monitoring response to adjuvant radiochemotherapy in patients with primary cervical cancer--results of a companion protocol of the randomized NOGGO-AGO phase III clinical trial.
Uterine Cervical Neoplasms
Semi-quantitative expression of tissue inhibitor of matrix metalloproteinase-2 in cancer of uterine cervix.
Uterine Cervical Neoplasms
Stromal cells play a role in cervical cancer progression mediated by MMP-2 protein.
Uterine Cervical Neoplasms
TCEB3 is Regulated by Circ-0000212/miR-140-3p Axis to Promote the Progression of Cervical Cancer.
Uterine Cervical Neoplasms
The aqueous extract of Ficus religiosa induces cell cycle arrest in human cervical cancer cell lines SiHa (HPV-16 Positive) and apoptosis in HeLa (HPV-18 positive).
Uterine Cervical Neoplasms
The association of semaphorin 5A with lymph node metastasis and adverse prognosis in cervical cancer.
Uterine Cervical Neoplasms
The invasiveness of human cervical cancer associated to the function of NaV1.6 channels is mediated by MMP-2 activity.
Uterine Cervical Neoplasms
The protective role of the -1306C>T functional polymorphism in matrix metalloproteinase-2 gene is associated with cervical cancer: implication of human papillomavirus infection.
Uterine Cervical Neoplasms
Tumoral and stromal expression of MMP-2, MMP-9, MMP-14, TIMP-1, TIMP-2, and VEGF-A in cervical cancer patient survival: a competing risk analysis.
Uterine Cervical Neoplasms
[Baicalein induces HeLa cell growth inhibition by down-regulation of matrix metalloproteinases and activating extracellular signal-regulated kinase].
Uterine Cervical Neoplasms
[FABP5 promotes cell growth, invasion and metastasis in cervical cancer].
Uterine Cervical Neoplasms
[The expression of matrix metalloproteinase-2 and -9 in cervical cancer and a study of their relationship]
Uterine Cervical Neoplasms
[The Role and Mechanism of CXCR4 and Its Ligand SDF-1 in the Development of Cervical Cancer Metastasis.]
Uterine Prolapse
Expression of matrix metalloproteinase-2 and tissue inhibitors of metalloproteinase-1 (TIMP-1, TIMP-2 and TIMP-3) in women with uterine prolapse but without urinary incontinence.
Uterine Prolapse
Gene expression and immunoreactivity of elastolytic enzymes in the uterosacral ligaments from women with uterine prolapse.
Uterine Prolapse
High isoprostane level in cardinal ligament-derived fibroblasts and urine sample of women with uterine prolapse.
Uveitis
Correlation of metalloproteinase-2 and -9 with proinflammatory cytokines interleukin-1b, interleukin-12 and the interleukin-1 receptor antagonist in patients with chronic uveitis.
Uveitis
Inhibition of MMP-dependent chemotaxis and amelioration of experimental autoimmune uveitis with a selective metalloproteinase-2 and -9 inhibitor.
Uveitis
Neutrophil accumulation correlates with type IV collagenase/gelatinase activity in endotoxin induced uveitis.
v-cath endopeptidase deficiency
Double deficiency of cathepsins B and L results in massive secretome alterations and suggests a degradative cathepsin-MMP axis.
Vaccinia
Expression of human recombinant 72 kDa gelatinase and tissue inhibitor of metalloproteinase-2 (TIMP-2): characterization of complex and free enzyme.
Vaginosis, Bacterial
Relationship between metalloproteinase-2 and -9 levels in plasma and vaginal secretion with preterm birth.
Varicocele
Impact of micronised purified flavonoid fraction on increased malondialdehyde and decreased metalloproteinase-2 and metalloproteinase-9 levels in varicocele: outcome of an experimentally induced varicocele.
Varicose Ulcer
Matrix metalloproteinase (MMP)-1 and MMP-2, but not COX-2 serve as additional predictors for chronic venous ulcer healing.
Varicose Ulcer
Matrix Metalloproteinases in Vascular Disease - A Potential Therapeutic Target?
Varicose Ulcer
The Impact of Differential Expression of Extracellular Matrix Metalloproteinase Inducer, Matrix Metalloproteinase-2, Tissue Inhibitor of Matrix Metalloproteinase-2 and PDGF-AA on the Chronicity of Venous Leg Ulcers.
Varicose Ulcer
The Impact of Valvular Oxidative Stress on the Development of Venous Stasis Ulcer Valvular Oxidative Stress and Venous Ulcers.
Varicose Veins
Comparison of extracellular matrix in skin and saphenous veins from patients with varicose veins: does the skin reflect venous matrix changes?
Varicose Veins
Effect of a Peptide Construct on Differentiated Macrophage MMP-2 and MMP-9 Levels of Varicose Patients.
Varicose Veins
Expression of matrix metalloproteinase-2 and -13 and tissue inhibitor of metalloproteinase-4 in varicose veins.
Varicose Veins
In vitro differences between smooth muscle cells derived from varicose veins and normal veins.
Varicose Veins
Increased TIMP/MMP ratio in varicose veins: a possible explanation for extracellular matrix accumulation.
Varicose Veins
Matrix metalloproteinase 2-induced venous dilation via hyperpolarization and activation of K+ channels: relevance to varicose vein formation.
Varicose Veins
MMP-2 Induced Vein Relaxation via Inhibition of [Ca(2+)](e)-Dependent Mechanisms of Venous Smooth Muscle Contraction. Role of RGD Peptides.
Varicose Veins
Morphologic characteristics of varicose veins: possible role of metalloproteinases.
Varicose Veins
Tissue inhibitor of metalloproteinase-1 is increased in the saphenofemoral junction of patients with varices in the leg.
Vascular Calcification
Gelatinases promote calcification of vascular smooth muscle cells by up-regulating bone morphogenetic protein-2.
Vascular Calcification
Involvement of matrix metalloproteinase-2 in the development of medial layer vascular calcification in uremic rats.
Vascular Calcification
The Involvement of miR-29b-3p in Arterial Calcification by Targeting Matrix Metalloproteinase-2.
Vascular Calcification
The matrix metalloproteinases 2 and 9 initiate uraemic vascular calcifications.
Vascular Calcification
Vascular smooth muscle cell differentiation to an osteogenic phenotype involves matrix metalloproteinase-2 modulation by homocysteine.
Vascular Calcification
Vitamin D receptor activators inhibit vascular smooth muscle cell mineralization induced by phosphate and TNF-?
Vascular Diseases
Aging is associated with increased matrix metalloproteinase-2 activity in the human aorta.
Vascular Diseases
Angiotensin II Induces the Vascular Expression of VEGF and MMP-2 in vivo: Preventive Effect of Red Wine Polyphenols.
Vascular Diseases
Effect of erythromycin on homocysteine-induced extracellular matrix metalloproteinase-2 production in cultured rat vascular smooth muscle cells.
Vascular Diseases
Effects of age, gender, ethnicity, diurnal variation and exercise on circulating levels of matrix metalloproteinases (MMP)-2 and -9, and their inhibitors, tissue inhibitors of matrix metalloproteinases (TIMP)-1 and -2.
Vascular Diseases
In vitro inhibition of human MMP-2 collagenolytic and gelatinolytic activity by neutralizing monoclonal antibodies.
Vascular Diseases
Inhibition of lysyl oxidase stimulates TGF-? signaling and metalloproteinases-2 and -9 expression and contributes to the disruption of ascending aorta in rats: protection by propylthiouracil.
Vascular Diseases
Involvement of Matrix Metalloproteinase 9 in Vertebral Arterial Dissection With Posterior Circulation Ischemic Stroke.
Vascular Diseases
Optical Interference-Free Surface-Enhanced Raman Scattering CO-Nanotags for Logical Multiplex Detection of Vascular Disease-Related Biomarkers.
Vascular Malformations
Cellular markers that distinguish the phases of hemangioma during infancy and childhood.
Vascular System Injuries
Activation of MMP-2 in response to vascular injury is mediated by phosphatidylinositol 3-kinase-dependent expression of MT1-MMP.
Vascular System Injuries
Adventitial endothelial implants reduce matrix metalloproteinase-2 expression and increase luminal diameter in porcine arteriovenous grafts.
Vascular System Injuries
Antagonism of platelet-derived growth factor by perivascular gene transfer attenuates adventitial cell migration after vascular injury: new tricks for old dogs?
Vascular System Injuries
Flow regulation of 72-kD collagenase IV (MMP-2) after experimental arterial injury.
Vascular System Injuries
Function of the plasminogen/plasmin and matrix metalloproteinase systems after vascular injury in mice with targeted inactivation of fibrinolytic system genes.
Vascular System Injuries
Hydrogen sulfide protects against vascular remodeling from endothelial damage.
Vascular System Injuries
Increased expression of membrane-type matrix metalloproteinase and preferential localization of matrix metalloproteinase-2 to the neointima of balloon-injured rat carotid arteries.
Vascular System Injuries
Matrix metalloproteinase-2 knockout prevents angiotensin II-induced vascular injury.
Vascular System Injuries
Montelukast inhibits matrix metalloproteinases expression in atherosclerotic rabbits.
Vascular System Injuries
OS 15-02 MATRIX METALLOPROTEINASE 2 KNOCKOUT PROTECTS FROM ANGIOTENSIN II-INDUCED VASCULAR INJURY IN PART VIA INHIBITION OF EGFR AND ERK1/2 ACTIVATION.
Vascular System Injuries
Platelets release active matrix metalloproteinase-2 in vivo in humans at a site of vascular injury: lack of inhibition by aspirin.
Vascular System Injuries
Role of the fibrinolytic and matrix metalloproteinase systems in arterial neointima formation after vascular injury.
Vascular System Injuries
Stromelysin-1 (MMP-3)-independent gelatinase expression and activation in mice.
Vascular System Injuries
Thrombin promotes activation of matrix metalloproteinase-2 produced by cultured vascular smooth muscle cells.
Vasculitis
Modulation of MMP-2 and MMP-9 in Churg-Strauss syndrome respiratory mucosa: potential monitoring parameters.
Vasculitis
Neutrophil gelatinase levels in plasma and synovial fluid of patients with rheumatic diseases.
Vasculitis
Serum MMP-2 and MMP-9 in patients with Behçet's disease: Do their higher levels correlate to vasculo-Behçet's disease associated with aneurysm formation?
Vasculitis
Suppression of Neutrophil-Mediated Tissue Damage-A Novel Skill of Mesenchymal Stem Cells.
Vasculitis
Urinary matrix metalloproteinases reflect renal damage in anti-neutrophil cytoplasm autoantibody-associated vasculitis.
Venereal Tumors, Veterinary
Immunocharacterization of matrix metalloproteinase-2 and matrix metalloproteinase-9 in canine transmissible venereal tumors.
Venous Insufficiency
Effect of oxidised regenerated cellulose/collagen matrix on proteases in wound exudate of patients with chronic venous ulceration.
Venous Insufficiency
Sulodexide Improves Contraction and Decreases Matrix Metalloproteinase-2 and -9 in Veins Under Prolonged Stretch.
Venous Thrombosis
Differential transcriptional activation of matrix metalloproteinase-2 and membrane type-1 matrix metalloproteinase by experimental deep venous thrombosis and thrombin.
Venous Thrombosis
Expression variations and clinical significance of MMP-1, MMP-2 and inflammatory factors in serum of patients with deep venous thrombosis of lower extremity.
Venous Thrombosis
Immunohistochemical detection of MMP-2 and MMP-9 in a stasis-induced deep vein thrombosis model and its application to thrombus age estimation.
Venous Thrombosis
Myeloid p53 regulates macrophage polarization and venous thrombus resolution by inflammatory vascular remodeling in mice.
Venous Thrombosis
Resistin Promotes Thrombosis in Rats with Deep Vein Thrombosis via Up-Regulating MMP-2, MMP-9, and PAI-1.
Ventricular Dysfunction
Early measurements of plasma matrix metalloproteinase-2 predict infarct size and ventricular dysfunction in ST-elevation myocardial infarction.
Ventricular Dysfunction
Soluble TNF receptors prevent apoptosis in infiltrating cells and promote ventricular rupture and remodeling after myocardial infarction.
Ventricular Dysfunction, Left
Ethanol extract from Epimedium brevicornum attenuates left ventricular dysfunction and cardiac remodeling through down-regulating matrix metalloproteinase-2 and -9 activity and myocardial apoptosis in rats with congestive heart failure.
Ventricular Dysfunction, Left
Euterpe oleracea Mart. (Açai) Supplementation Attenuates Acute Doxorubicin-Induced Cardiotoxicity in Rats.
Ventricular Dysfunction, Left
Icariin attenuates cardiac remodelling through down-regulating myocardial apoptosis and matrix metalloproteinase activity in rats with congestive heart failure.
Ventricular Dysfunction, Left
Plasma MMP-9 and MMP-2 following acute myocardial infarction in man: correlation with echocardiographic and neurohumoral parameters of left ventricular dysfunction.
Ventricular Dysfunction, Left
Relationships between plasma levels of matrix metalloproteinases and neurohormonal profile in patients with heart failure.
Ventricular Fibrillation
Dynamic alterations of connexin43, matrix metalloproteinase-2 and tissue inhibitor of matrix metalloproteinase-2 during ventricular fibrillation in canine.
Viremia
Silybin-vitamin E-phospholipids complex reduces liver fibrosis in patients with chronic hepatitis C treated with pegylated interferon ? and ribavirin.
Virus Diseases
Acute exacerbations of COPD are associated with significant activation of matrix metalloproteinase 9 irrespectively of airway obstruction, emphysema and infection.
Virus Diseases
In vitro infection of macrophages by HIV: correlation with cellular activation, synthesis of tumour necrosis factor alpha and proteolytic activity.
Virus Diseases
Increased expression of matrix metalloproteinase-2 and 9 and human papilloma virus infection are associated with malignant transformation of sinonasal inverted papilloma.
Virus Diseases
Increased intrahepatic cyclooxygenase 2, matrix metalloproteinase 2, and matrix metalloproteinase 9 expression is associated with progressive liver disease in chronic hepatitis C virus infection: role of viral core and NS5A proteins.
Virus Diseases
Influenza A virus infection modulates the expression of type IV collagenase in epithelial cells.
Virus Diseases
Regulation of Matrix Metalloproteinases-2 and -9 Gene Expression in Cultured Human Fetal Membrane Cells by Influenza Virus Infection.
Virus Diseases
Severity of Plasma Leakage Is Associated With High Levels of Interferon ?-Inducible Protein 10, Hepatocyte Growth Factor, Matrix Metalloproteinase 2 (MMP-2), and MMP-9 During Dengue Virus Infection.
Vitamin A Deficiency
Neutrophil cathepsin G is specifically decreased under vitamin A deficiency.
Vitamin D Deficiency
Role of Paricalcitol in Modulating the Immune Response in Patients with Renal Disease.
Vitamin D Deficiency
Vitamin D deficiency promotes large rupture-prone abdominal aortic aneurysms and cholecalciferol supplementation limits progression of aneurysms in a mouse model.
Vitiligo
Altered levels of Ets-1 transcription factor and metalloproteinases in melanocytes from vitiligo patients.
Vitiligo
In vitro migration of melanoblasts requires matrix metalloproteinase-2: implications to vitiligo therapy by photochemotherapy.
Vitiligo
The clinical and pathological effectiveness of microneedling and topical 5-fluorouracil in vitiligo treatment: An association with matrix metalloproteinase 2 immunohistochemical expression.
Vitreoretinopathy, Proliferative
Predominance of MMP-1 and MMP-2 in epiretinal and subretinal membranes of proliferative vitreoretinopathy.
Vitreous Detachment
Intravitreal plasmin injection activates endogenous matrix metalloproteinase-2 in rabbit and human vitreous.
Vitreous Hemorrhage
The activated form of gelatinase B/matrix metalloproteinase-9 is associated with diabetic vitreous hemorrhage.
Whooping Cough
Cyclic strain-mediated regulation of endothelial matrix metalloproteinase-2 expression and activity.
Whooping Cough
Fibronectin upregulates gelatinase B (MMP-9) and induces coordinated expression of gelatinase A (MMP-2) and its activator MT1-MMP (MMP-14) by human T lymphocyte cell lines. A process repressed through RAS/MAP kinase signaling pathways.
Whooping Cough
Role of MMP-2 in PKCdelta-mediated inhibition of Na+ dependent Ca2+ uptake in microsomes of pulmonary smooth muscle: involvement of a pertussis toxin sensitive protein.
Wilms Tumor
Renal Fibrosis mRNA Classifier: Validation in Experimental Lithium-Induced Interstitial Fibrosis in the Rat Kidney.
Wilms Tumor
Suppression of tumorigenicity of rhabdoid tumor derived G401 cells by the multivalent HB-19 pseudopeptide that targets surface nucleolin.
Wiskott-Aldrich Syndrome
Enterolobium contortisiliquum trypsin inhibitor (EcTI), a plant proteinase inhibitor, decreases in vitro cell adhesion and invasion by inhibition of Src protein-focal adhesion kinase (FAK) signaling pathways.
Wound Infection
Matrix metalloproteinases in rectal mucosa, tumour and plasma: response after preoperative irradiation.
Wound Infection
Methamphetamine Alters the Antimicrobial Efficacy of Phagocytic Cells during Methicillin-Resistant Staphylococcus aureus Skin Infection.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
0.134
Acetyl-Pro-Leu-Gly-thioester-Leu-Leu-Gly ethyl ester
-
gelatinase A synthetic 19000 MW catalytic domain
0.159
fibrinogen
-
cleavage of the alpha-chain of the native substrate, full-length MMP-2, pH 7.1, 37°C
-
0.136
Ac-Pro-Leu-Gly-[2-mercapto-4-methylpentanoyl]-Leu-Gly-OEt
-
pH 7.5, 37°C, GaCD, without fibronectin-like insert
0.172
Ac-Pro-Leu-Gly-[2-mercapto-4-methylpentanoyl]-Leu-Gly-OEt
-
pH 7.5, 37°C, GaCDfn, with fibronectin-like insert
0.059
Dnp-Pro-beta-cyclohexyl-Ala-Gly-Cys(Me)-His-Ala-Lys(N-Me-Abz)-NH2
-
pH 7.5, 37°C, GaCD, without fibronectin-like insert
0.118
Dnp-Pro-beta-cyclohexyl-Ala-Gly-Cys(Me)-His-Ala-Lys(N-Me-Abz)-NH2
-
pH 7.5, 37°C, GaCDfn, with fibronectin-like insert
0.0057
Mca-Pro-Leu-Gly-Leu-Dap-Ala-Arg-NH2
-
pH 7.5, 37°C, GaCDfn, with fibronectin-like insert
0.0099
Mca-Pro-Leu-Gly-Leu-Dap-Ala-Arg-NH2
-
pH 7.5, 37°C, GaCD, without fibronectin-like insert
additional information
additional information
-
kinetics of trunacted enzyme and modified fibrinogen substrates, Michaelis-Menten mechanism, overview
-
additional information
additional information
-
kinetic analysis of LS276-THP hydrolysis by MMP-2
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
36.4
fibrinogen
-
cleavage of the alpha-chain of the native substrate, full-length MMP-2, pH 7.1, 37°C
-
16.7
Ac-Pro-Leu-Gly-[2-mercapto-4-methylpentanoyl]-Leu-Gly-OEt
-
pH 7.5, 37°C, GaCD, without fibronectin-like insert
19.5
Ac-Pro-Leu-Gly-[2-mercapto-4-methylpentanoyl]-Leu-Gly-OEt
-
pH 7.5, 37°C, GaCDfn, with fibronectin-like insert
4.7
Dnp-Pro-beta-cyclohexyl-Ala-Gly-Cys(Me)-His-Ala-Lys(N-Me-Abz)-NH2
-
pH 7.5, 37°C, GaCDfn, with fibronectin-like insert
5.4
Dnp-Pro-beta-cyclohexyl-Ala-Gly-Cys(Me)-His-Ala-Lys(N-Me-Abz)-NH2
-
pH 7.5, 37°C, GaCD, without fibronectin-like insert
0.6
Mca-Pro-Leu-Gly-Leu-Dap-Ala-Arg-NH2
-
pH 7.5, 37°C, GaCDfn, with fibronectin-like insert
1.7
Mca-Pro-Leu-Gly-Leu-Dap-Ala-Arg-NH2
-
pH 7.5, 37°C, GaCD, without fibronectin-like insert
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
kcat/KM VALUE [1/mMs-1]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Ki VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
IC50 VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
0.00028
(2E)-3-(N-hydroxycarbamoyl)-2-(3-phenylpropylidene)propionyl-L-tryptophan-N-methylamide
Homo sapiens
-
-
0.000123
(2E)-3-(N-hydroxycarbamoyl)-2-heptylidenepropionyl-L-tryptophan-N-methylamide
Homo sapiens
-
-
0.0000092
(2E)-3-(N-hydroxycarbamoyl)-2-isopropionyl-L-tryptophan-N-methylamide
Homo sapiens
-
-
0.00012
(2E)-3-(N-hydroxycarbamoyl)-2-[(2E)-3-phenylprop-2-en-1-ylidene]propionyl-L-tryptophan-N-methylamide
Homo sapiens
-
-
0.0785
(2E)-3-(N-hydroxycarbamoyl)-2-[(2E)-but-2-en-1-ylidene]propionyl-L-tryptophan-N-methylamide
Homo sapiens
-
-
0.000188
2-([4-[3'-(2-aminoethoxy)-2-methylbiphenyl-4-yl]piperidin-1-yl]sulfonyl)-N-hydroxy-2-methylpropanamide
Homo sapiens
-
-
0.000009
2-[(4-biphenyl-4-yl-3,6-dihydropyridin-1(2H)-yl)sulfonyl]-N-hydroxyacetamide
Homo sapiens
-
-
0.000534
2-[(4-[3'-[2-(dimethylamino)ethoxy]-2-methylbiphenyl-4-yl]piperidin-1-yl)sulfonyl]-N-hydroxy-2-methylpropanamide
Homo sapiens
-
-
0.000776
2-[[4-(2,3'-dimethylbiphenyl-4-yl)-3,6-dihydropyridin-1(2H)-yl]sulfonyl]-N-hydroxyacetamide
Homo sapiens
-
-
0.00062
2-[[4-(2-chlorobiphenyl-4-yl)-3,6-dihydropyridin-1(2H)-yl]sulfonyl]-N-hydroxyacetamide
Homo sapiens
-
-
0.00438
2-[[4-(2-ethylbiphenyl-4-yl)-3,6-dihydropyridin-1(2H)-yl]sulfonyl]-N-hydroxyacetamide
Homo sapiens
-
-
0.000017
2-[[4-(2-fluorobiphenyl-4-yl)-3,6-dihydropyridin-1(2H)-yl]sulfonyl]-N-hydroxyacetamide
Homo sapiens
-
-
0.000998
2-[[4-(3'-ethoxy-2-methylbiphenyl-4-yl)-3,6-dihydropyridin-1(2H)-yl]sulfonyl]-N-hydroxyacetamide
Homo sapiens
-
-
0.000457
2-[[4-(3'-ethoxy-2-methylbiphenyl-4-yl)piperidin-1-yl]sulfonyl]-N-hydroxy-2-methylpropanamide
Homo sapiens
-
-
0.001208
2-[[4-(3'-ethyl-2-methylbiphenyl-4-yl)-3,6-dihydropyridin-1(2H)-yl]sulfonyl]-N-hydroxyacetamide
Homo sapiens
-
-
0.00308
N-hydroxy-2-([4-[2-(trifluoromethyl)biphenyl-4-yl]-3,6-dihydropyridin-1(2H)-yl]sulfonyl)acetamide
Homo sapiens
-
-
0.000173
N-hydroxy-2-([4-[2-methyl-3'-(trifluoromethoxy)biphenyl-4-yl]-3,6-dihydropyridin-1(2H)-yl]sulfonyl)acetamide
Homo sapiens
-
-
0.000262
N-hydroxy-2-([4-[3'-(2-hydroxyethoxy)-2-methylbiphenyl-4-yl]piperidin-1-yl]sulfonyl)-2-methylpropanamide
Homo sapiens
-
-
0.000853
N-hydroxy-2-([4-[3'-(2-methoxyethoxy)-2-methylbiphenyl-4-yl]piperidin-1-yl]sulfonyl)-2-methylpropanamide
Homo sapiens
-
-
0.000196
N-hydroxy-2-([4-[3'-(methoxymethyl)-2-methylbiphenyl-4-yl]-3,6-dihydropyridin-1(2H)-yl]sulfonyl)acetamide
Homo sapiens
-
-
0.000196
N-hydroxy-2-methyl-2-[(4-[2-methyl-3'-[2-(methylamino)ethoxy]biphenyl-4-yl]piperidin-1-yl)sulfonyl]propanamide
Homo sapiens
-
-
0.000529
N-hydroxy-2-[(4-[4-[6-(2-hydroxyethoxy)pyridin-2-yl]-3-methylphenyl]piperidin-1-yl)sulfonyl]-2-methylpropanamide
Homo sapiens
-
-
0.00032
N-hydroxy-2-[[4-(2-methylbiphenyl-4-yl)-3,6-dihydropyridin-1(2H)-yl]sulfonyl]acetamide
Homo sapiens
-
-
0.000222
N-hydroxy-2-[[4-(3'-methoxy-2-methylbiphenyl-4-yl)-3,6-dihydropyridin-1(2H)-yl]sulfonyl]acetamide
Homo sapiens
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
additional information
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
7.4
7.5
7.5
7.6
7
-
acetyl-Pro-Leu-Gly-thioester-Leu-Leu-Gly ethyl ester, gelatinase A synthetic 19000 MW catalytic domain
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
pH RANGE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
6 - 9
-
pH 6.0: about 40% of activity maximum, pH 9.0: about 85% of activity maximum, azocoll
6 - 9.3
-
activity range, pH-dependence of catalytic parameters for MMP-2 on fibrinogen, pH-dependence of the rate-limiting step shows a bell-shaped profile, overview
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
TEMPERATURE OPTIMUM
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
37
37
-
assay at
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
pI VALUE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
ORGANISM
COMMENTARY
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
SOURCE
the enzyme is overexpressed in tumors, it is expressed in all tumors tested
brenda
higher intensity of staining of MMP-2 is observed in regions of invasion of the muscularis mucosa compared with superficial portions of the tumor in colorectal cancer
brenda
distribution and activation of matrix metalloproteinase-2 in skeletal muscle fibers, quantification of MMP2 in muscle, overview
brenda
Mycobacterium tuberculosis stimulates matrix metalloproteinases secretion in the host. Analysis of the patterns of matrix metalloproteinase 9 (MMP-9) and 2 (MMP-2) isoforms in sputum samples, overview
brenda
-
demineralized dentin matrix, extraction is best at acidic conditions of pH 2-3 compared to pH 7.4-EDTA-containing extracts
brenda
-
derived from premenopausal women aged 45-55 years who underwent total abdominal hysterectomy
brenda
-
plasma prepared from blood emerging from a skin wound inflicted for the measurement of the bleeding time, shed blood, and simultaneously from venous blood in 27 healthy human volunteers, with and without treatment of the individuals with acetylsalicylic acid before. MMP-2 activity is higher in shed blood. Acetylsalicylic acid has no effect on MMP-2 secretion, overview
brenda
-
tissue samples of oral squamous cell carcinomas
brenda
-
fibroids of different size show equal MMP-2 activity
brenda
additional information
recombinant pro-enzyme and recombinant mature, activated enzyme
brenda
the enzyme is upregultaed compared to control brain
brenda
-
human platelets contain matrix metalloproteinase 2 and release it upon activation
brenda
-
conditioned medium from T98G human glioblastoma cells
brenda
-
from H-ras-transformed human bronchial epithelial cells (TBE-1)
brenda
-
from HeLa cells co-infected with each of the recombinant Vaccinia viruses and with vTF7-3
brenda
-
enzyme level and expression analysis in response to advanced glycation products
brenda
additional information
quantitative real time PCR enzyme expression analysis and immunohistochemic analysis in glioblastoma
brenda
additional information
-
quantitative real time PCR enzyme expression analysis and immunohistochemic analysis in glioblastoma
brenda
additional information
circulating hMMP2is significantly increased in diabetic patients compared to controls and significantly correlated with the serum C-peptide levels
brenda
additional information
-
circulating hMMP2is significantly increased in diabetic patients compared to controls and significantly correlated with the serum C-peptide levels
brenda
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY
GeneOntology No.
LITERATURE
SOURCE
besides MT-MMPs, which efficiently bind proMMP-2 to induce its activation, a limited number of cell-surface molecules have been shown to contribute to enhance proteolytic activity at the migrating front of invasive cells by clustering active MMP-2 at the cell membrane. Among them the heat shock protein HSP90a expressed at the surface of tumor cells promotes MMP-2 activity and tumor invasion by binding to the Hpx-like domain of MMP-2. The alphanybeta3 integrin is first identified as a binding site for the C-terminal Hpx-like domain of MMP-2 in studies investigating in vivo and in vitro interactions between angiogenic blood vessels and melanoma cells
brenda
-
main localization in invertebral disc, immunohistochemic analysis, overview
brenda
additional information
the enzyme sequence contains a 29-residues-signal peptide responsible for translocation to the endoplasmic reticulum. Secreted enzyme MMP-2 can be endocytosed through direct or indirect binding to several membrane proteins, translocation across the endosome membrane towards the cytosol. Besides its transient journey in the secretory pathway (endoplasmic reticulum, Golgi apparatus and related vesicles), intracellular MMP-2 is not restricted to the cytosol but is also found in organelles including nucleus and mitochondria. proMMP-2 can be secreted either in a free form or already complexed with TIMP-2 through its C-terminal domain. LRP-2 is able to bind and endocytose proMMP-2 complexed to TIMP-2
-
brenda
the enzyme is secreted. proMMP-2 can be secreted either in a free form or already complexed with TIMP-2 through its C-terminal domain. Extracellular association of proMMP-2 and TIMP-2 depends on TIMP-2 phosphorylation by extracellular c-Src tyrosine kinase
-
brenda
-
-
-
brenda
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
malfunction
physiological function
malfunction
-
the inactivation of the MMP-2 gene prevents thrombosis induced by weak, but not strong, stimuli but produces only a moderate prolongation of the bleeding time. MMP-2 deficient mice have hyporeactive platelets, a defective thrombotic response and mildly impaired hemostasis
additional information
malfunction
induction of diabetes in transgenic mice overexpressing human MMP2 show ignificant improvements in glycemia, glucose tolerance and insulin secretion compared to diabetic wild-type mice. Increased hMMP2 levels in mice correlate with significant reduction in islet beta-cell apoptosis compared to wild-type counterparts, and an inhibitor of hMMP2 reverses this mitigating activity against diabetes
malfunction
women with endometriosis show decreased MMP-2 activity in eutopic endometrium as compared to women without endometriosis, while ectopic ovarian endometrioma show significantly elevated MMP-2 activity with disease severity. Increased MMP-2 activation with disease progression
physiological function
enzyme MMP-2 is considered a major enzyme involved in the turnover of the extracellular matrix. The enzyme is involved in the degradation of fibrillin-1 and fibrillin-2, the degradation patterns differ between the eye and the periodontal ligaments, possibly reflecting the sensitivity of fibrillin-1 and fibrillin-2 of each type of oxytalan fiber against enzyme MMP-2
physiological function
the enzyme act as important oncogenes that improve invasiveness of cancer cells
physiological function
chronic progression of diabetes is associated with decreased pancreatic islet mass due to apoptosis of beta-cells. Patients with diabetes have increased circulating matrix metalloproteinase-2 (MMP2). MMP2 might inhibit cell apoptosis, including islet beta-cells. The increased activation of Akt and BAD induced by hMMP2 in beta-cells compared to controls, links this signaling pathway to the anti-apoptotic activity of hMMP2, a property that is reversible by both an hMMP2 inhibitor and antibody against integrin-beta3. hMMP2 may attenuate the severity of diabetes by protecting islet beta-cells from apoptosis through an integrin-mediated activation of the Akt/BAD pathway. Preliminary treatment of cells, e.g. HepG2 cells, HUVE cells, and NHM cells, with active hMMP2 for 30-min significantly inhibits apoptosis (induced by starvation), hMMP2 inhibits apoptosis of beta-cell lines, which is modulated by intergrins
physiological function
matrix metalloproteinase MMP-2 degrades components of the extracellular matrix, denatured interstitial type I collagen and native type IV collagen. MMP-2 is a key player in cancer invasion and metastasis. Different mechanisms contribute to regulate the activity of MMP-2 during its molecular existence: expression, secretion, activation, extra/pericellular localization, inhibition, endocytosis and lysosomal degradation. Epigenetic control also contributes to MMP-2 regulation. Levels of control of extra/pericellular MMP-2, overview The enzyme is present in the extracellular compartment for degrading denatured type I collagen. Cell membrane-bound MMP-2 can also act as transducers and trigger outside-in signaling. Binding of proMMP-2 to alphavbeta3 integrin on the surface of lung cancer cells stimulates tumor angiogenesis by activating PI3K/AKT pathway and HIF-1alpha, leading to VEGF-A expression
physiological function
matrix metalloproteinase-2 (gelatinase A) is a mediator of cancer metastasis, but it is also thought to be involved in several aspects of cancer development, including cell growth and inflammation. MMP-2 may be associated with colorectal cancer development and invasion in the Tunisian population
physiological function
MMP-2 isoforms do not seem to be directly involved with Mycobacterium tuberculosis evolution of infection
physiological function
regulation of matrix metalloproteinase-2 activity by COX-2-PGE2-pAKT axis promotes angiogenesis in endometriosis. Analysis of the regulation of MMP-2 activity in endothelial cells and on angiogenesis during progression of ovarian endometriosis, overview. Involvement of MT1MMP and TIMP-2 in MMP-2 activation during progression of endometriosis
physiological function
the enzyme exhibits gelatinolytic activity which is enhanced by p-aminophenylmercuric acetate (APMA). The APMA treated enzyme probably also produces proteolytic products of myosin and other muscle proteins
additional information
enzyme MMP-2 forms heterodimers with various proteins, including TIMP-2, TIMP-3, TIMP-4, and glycosaminoglycans. Disruption of the cysteine-zinc ion pairing by homodimerization of MMP-2 opens the active site, but it may accommodate only small peptide substrates. Thus, MMP-2 propeptide processing is a prerequisite to gain its proteolytic activity against large substrates, including gelatin
additional information
MMP-2 has two isoforms: the 72 kDa latent form and an active form of 62 kDa, which is generated from the 10 kDa pro-domain cut-off. MMP-2 isoforms identification and determination of activities, overview
additional information
-
MMP-2 has two isoforms: the 72 kDa latent form and an active form of 62 kDa, which is generated from the 10 kDa pro-domain cut-off. MMP-2 isoforms identification and determination of activities, overview
additional information
the Zn2+-binding motif of the catalytic domain is preceded by three cysteine-rich repeats comparable to the collagen-binding fibronectin type II (FN-II) repeats, which are required for recognizing collagen and elastin
additional information
-
the SDF-1a/CXCR4 axis is involved in osteopontininduced MMP-2 expression and activity, overview
additional information
-
thrombin-dependent MMP-2 activity is regulated by heparan sulfate, molecular mechanism, regulatory role of hemopexin-like domain in MMP-2 degradation, overview
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION
The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable).
The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable). MMP2_HUMAN
660
0
73882
Swiss-Prot
Secretory Pathway (Reliability: 2)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
PDB
SCOP
CATH
UNIPROT
ORGANISM
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
72000
47052
-
x * 66000, SDS-PAGE, x * 66518, calculated, enzyme mutant E404A, x * 59000, SDS-PAGE, x * 47052, calculated, enzyme mutant lacking collagen-binding domain
59000
-
x * 66000, SDS-PAGE, x * 66518, calculated, enzyme mutant E404A, x * 59000, SDS-PAGE, x * 47052, calculated, enzyme mutant lacking collagen-binding domain
62000
66000
66518
-
x * 66000, SDS-PAGE, x * 66518, calculated, enzyme mutant E404A, x * 59000, SDS-PAGE, x * 47052, calculated, enzyme mutant lacking collagen-binding domain
68000
72000
66000
-
x * 66000, SDS-PAGE, x * 66518, calculated, enzyme mutant E404A, x * 59000, SDS-PAGE, x * 47052, calculated, enzyme mutant lacking collagen-binding domain
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
SUBUNIT
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
homodimer
homodimerization of enzyme MMP-2, through an intermolecular disulfide bond between Cys102 and the neighboring Cys102, requires Ca2+ but is not associated with protein kinase C-mediated phosphorylation. The cleavage is followed by intermolecular autoproteolytic cleavage at the Asn109-Tyr peptide bond, resulting in full enzymatic activation. Homodimerization of the enzyme enhances thrombin-mediated activation of pro-MMP-2
additional information
?
-
x * 66000, SDS-PAGE, x * 66518, calculated, enzyme mutant E404A, x * 59000, SDS-PAGE, x * 47052, calculated, enzyme mutant lacking collagen-binding domain
additional information
proMMP-2 consists of a signal peptide, a pro-peptide, a collagenase-like domain 1, a collagen-binding domain, a collagenase-like domain 2, and a hemopexin-like domain
additional information
enzyme MMP-2 forms heterodimers with various proteins, including TIMP-2, TIMP-3, TIMP-4, and glycosaminoglycans
additional information
MMP-2 has two isoforms: the 72 kDa latent form and an active form of 62 kDa, which is generated from the 10 kDa pro-domain cut-off. MMP-2 isoforms identification and determination of activities, overview
additional information
-
MMP-2 has two isoforms: the 72 kDa latent form and an active form of 62 kDa, which is generated from the 10 kDa pro-domain cut-off. MMP-2 isoforms identification and determination of activities, overview
additional information
-
native and denatured collagen binding properties reside in the fibronectin type II modules of enzyme, that is the collagen binding domain. Enzyme utilizes the collagen binding domain in cis for collagen binding and triple helicase activity
additional information
-
modeling of the interaction of fibrinogen with different truncated forms of MMP-2, i.e. the autoinhibitory procatalytic domain, the catalytic domain, the catalytic domain lacking the fibronectin-like domain, the fibronectin-like domain alone, and the haemopexin-like domain, using crystal structures isolated from the full-length proMMP-2, PDB ID 1CK7, overview
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
POSTTRANSLATIONAL MODIFICATION
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
phosphoprotein
proMMP-2 contains 29 potential phosphorylation sites, that at least five of these sites are phosphorylated, purified MMP-2 is phosphorylated by protein kinase C in vitro, peptide mass fingerprint for phosphorylation site determination, overview
proteolytic modification
additional information
proteolytic modification
concanavalin A induces the enzyme activation through membrane type 1 matrix metalloprotease from 72 kDA proenzyme to 62 kDa active enzyme in the non-pigmented ciliary epithelial cells and fibroblast from periodontal ligaments
proteolytic modification
the enzyme is activated by cleavage of it propeptide, activation stimulation involves concanavalin A
proteolytic modification
the enzyme is secreted as a zymogen and requires activation by cleavage of its propeptide
proteolytic modification
thrombin directly cleaves the propeptide of MMP-2 at specific sites, on the C-terminal side of Arg98 and Arg101 with a preference for Arg101, for enzyme activation. Heparan sulfate is required for thrombin-mediated activation of pro-MMP-2 by binding to thrombin, presumably through conformational changes at the active site of the enzyme. Homodimerization of MMP-2 enhances thrombin-mediated activation of pro-MMP-2
proteolytic modification
activation of pro-MMP-2 with 1 mM APMA (p-aminophenylmercuric acetate) for 1 h at 37°C, in buffer containing 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM CaCl2, and 0.05% Brij L23
proteolytic modification
p-aminophenylmercuric acetate (APMA) promotes activation of pro-MMP2 and its autocatalysis to active MMP2
proteolytic modification
the enzyme is secreted as an inactive pro-MMP and proteolytically activated to mature MMP-2. ProMMP-2 is composed of a propeptide followed by a catalytic domain that is connected to a hemopexin (Hpx)-like domain through a linker sequence. A free zinc-ligating thiol group present in the propeptide maintains the enzyme latency until activation (cysteine switch). The latent proform of most MMPs is generally processed in the extracellular compartment by proteolytic removal of the about 10-kDa. proMMP-2 cannot be fully activated by most extracellular proteinases. For example, thrombin alone is unable to fully activate proMMP-2 and activation of proMMP-2 by neutrophil elastase, cathepsin G or proteinase-3 depends on the expression of membrane-type 1 MMP (MT1-MMP). A prominent mechanism for proMMP-2 activation occurs at the cell surface and depends on the MT-MMPs, mainly MT1-MMP. The six MT-MMPs are associated to cell membranes by either a type I transmembrane domain (MT1-, MT2-, MT3-and MT5-MMPs) or a glycosylphosphatidylinositol (GPI) anchor (MT4- and MT6-MMPs). Their pericellular activities are diverse and include ECM degradation and shedding and activation processes. Only MT4-MMP does not activate proMMP-2. The recombinant catalytic domain of MT5-MMP generates the active form of MMP-2. Activation of proMMP-2 by MT3-MMP requires a preliminary interaction between chondroitin sulfate glycosaminoglycans expressed at the cell surface and the Hpx-like domain of proMMP-2. MT2-MMP activates proMMP-2 by directly interacting with the Hpx-like domain of the proenzyme. Mechanisms of proMMP-2 activation by MT1-MMP involve tissue inhibitor of metalloproteinases-2 (TIMP-2), a physiological inhibitor of MMPs
additional information
-
activation of pro-MMP-2 by 4-aminophenylmercuric acetate
additional information
-
artificial biotinylation of the purified recombinant CBD domain for library screening, overview
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
4-bladed beta-propeller protein in which the 4 blades are arranged around a channel-like opening in which Ca2+ and a Na+Cl- ion pair are bound
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
E404A
-
no enzymic activity, competition with isolated collagen-binding domain and with matrix metalloproteinase MMP-9 binding to native and denatured type I collagen
additional information
additional information
generation of transgenic C57BL/6 mice overexpressing human MMP2, phenotype, overview
additional information
-
generation of transgenic C57BL/6 mice overexpressing human MMP2, phenotype, overview
additional information
-
recombinant collagen binding domain of enzyme, competitive inhibition of gelatin binding to intact enzyme by 73%, inhibition of enzyme-dependent cleavage of an 11 amino acid short protein fragment by less than 10%
additional information
-
recombinant enzyme lacking collagen-binding domain, does not block binding to gelatin of either enzyme mutant E404A or matrix metalloproteinase MMP-9 mutant E402A
additional information
-
construction of MMP-2 truncation mutants overview, an MMP-2 mutant, with deleted hemopexin-like domain and three fibronectin-like type II domains, and native MMP-2 show similar affinities for APP-IP, chimeric proteases, consisting of various parts of the MMP-2 catalytic domain and those of MMP-7 or MMP-9, show that Ala88 and Gly94 in the non-prime side and Tyr145 and Thr146 in the prime side of the substrate-binding cleft of MMP-2 contribute separately to the selective inhibition bei APP-PI, mutational interaction analysis, overview
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
TEMPERATURE STABILITY
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
GENERAL STABILITY
ORGANISM
UNIPROT
LITERATURE
the plasmatic half-life of human recombinant pro-MMP-2, assessed after the intravenous injection of 500 ng of the proenzyme in MMP-2-deficient mice is 19 min
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
native, extracellular, inhibitor-free enzyme from glioblastoma cell line T98G cell culture medium
recombinant enzyme from HeLa S3 cells, native enzyme purified from HT-1080 cells
recombinant soluble enzyme from Escherichia coli cell-free extract by gelatin affinity chromatography
recombinant CBD1, CBD2 and CBD3 polypeptides and fibronectin type-II-like modelues of MMP-2 from Escherichia coli, by gelatin affinity chromatography
-
recombinant His-tagged enzyme without pro-domain and isolated MMP-2 CBD domain from Escherichia coli inclusion bodies, after solubilization and refolding, by nickel affinity chromatography
-
second fibronectin type II module, residues 278-336, produced in Escherichia coli
-
solubilized, refolded recombinant GST-tagged MMP-2 by glutathione affinity chromatography, removal of the tag
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
gene MMP-2, quantitative real time PCR expression analysis in glioblastoma
gene MMP2, genotyping in Tunesian population. The levels of MMP-2 mRNA expression in patients containing the CC genotype are much higher compared with cells with the CT genotype. The frequency of the MMP-2 CC genotype is significantly higher in colorectal cancer patients when compared with controls
gene MMP2, the gene is located on the long arm of chromosome 16 at position q12.2, the cDNA for MMP-2 codes for a 660 residues preproenzyme containing a 29 residues signal peptide responsible for translocation to the endoplasmic reticulum and followed by the 72-kDa-proenzyme. The human MMP2 gene lacks a conventional TATA-box or classical transcription response elements found in other MMP genes, the constitutive expression depends on p53-, Sp1-, Sp3-and AP-2-binding sites but the promoter contains other cis-regulatory elements including C/EBP, ATF2, PEA3/Ets, c-myc and AP-1 binding sites. Transcriptionally active MMP-2 in invasive cancer cells is characterized by hypomethylation of CpG regions in the MMP2 promoter and low levels of histone H3 lysine-27 trimethylation
pro-MMP-2 expressed in a recombinant vaccinia virus mammalian cell expression system
recombinant enzyme from HeLa S3 cells infected with vaccinia virus encoding the full-length cDNA of pro-MMP-2
recombinant expression of soluble and functional full-length enzyme from plasmid pET5a-MMP-2 in the cytoplasm of Escherichia coli strain BL21(DE3)/pLysS, subcloning in Escherichia coli strain DH5alpha, method development and evaluation, overview
recombinant expression of wild-type and mutant full-length MMP-2 or MMP-2 with C-terminal Myc and His tags in COS-1 cells, secretion of the enzyme to the cell culture medium
cloned and overexpressed in a bacterial system, Escherichia coli BL21(DE3)pLysS
-
expression of GST-tagged MMP-2 in Escherichia coli strain DH5alpha in inclusion bodies
-
expression of the first, second, and third module, i.e. CBD1, CBD2 and CBD3 polypeptides, and of the fibronectin type-II-like modelues of MMP-2 in Escherichia coli
-
expression of the His-tagged enzyme without pro-domain and of the isolated MMP-2 CBD domain in Escherichia coli in inclusion bodies
-
second fibronectin type II module, residues 278-336, produced in Escherichia coli
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
EXPRESSION
ORGANISM
UNIPROT
LITERATURE
Mycobacterium tuberculosis stimulates matrix metalloproteinases secretion in the host
significant progressive increase in total MMP-2 plasma levels with progression from adenomatous polyps through advancing Dukes stages
expression and activity of MMP-2 is 6fold induced by osteopontin through binding to integrin avb3 and CD44v6 in hepatocellular carcinoma cells SMMC7721 and HepG2
-
inhibition of the SDF-1a/CXCR4 axis downregulates the rhOPN-induced MMP-2 expression and activity
-
matrix metalloproteinase 2 activity decreases in human periodontal ligament fibroblast cultures submitted to simulated orthodontic force by centrifugation (141xg) for 30, 60, 90, and 120 min at 24 h regardless of the duration of centrifugation and at 48 h in cells centrifuged for 30 min only
-
profibrogenic gene expression of MMP-2 is down-regulated (75% decrement) in response to adenoviral delivery of dominant-negative transforming growth factor beta type II receptor in hepatic stellate cells
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
RENATURED/Commentary
ORGANISM
UNIPROT
LITERATURE
recombinant GST-tagged enzyme from Escherichia coli inclusion bodies by solubilization of the inclusion bodies with guanidine-HCl followed by refolding by rapid dilution method
-
solubilization of recombinant His-tagged enzyme without pro-domain and isolated MMP-2 CBD domain from Escherichia coli inclusion bodies with 8 M urea, 0.1 M NaH2PO4 and 0.01 M Tris-HCl, pH 8.0, followed by refolding
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
APPLICATION
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
medicine
diagnostics
-
assessment of enzyme for monitoring and screening patients with prostate cancer. Significant correlation of densitometric analysis of enzyme activity and indirect hemagglutination titer, and prostate-specific antigen parameters
medicine
additional information
-
in patients with degenerative disc disease, proenzyme levels in nucleus pulposus of intervertebral disc are higher at early stages of the disease. Proenzyme and tissue inhibitor of metalloproteinase-2 levels negatively correlate in herniated disc samples, and proenzyme levels negatively correlate with the collagen content
medicine
understanding the detailed molecular structures and the comformational changes of MMP-2 in its zymogen, active, and inhibited states can aid in the rational design of anti-cancer drugs
medicine
-
attractive therapeutic target for cancer invasion and metastasis, morbidity and mortality of cancer patients are directly related to the ability of tumor cells to metastasize, gelatinase A is required by metastazing tumor cells to traverse basement membrane at tissue bounaries and in blood vessels, therefore this enzyme is a promising target for the development of antitumor drugs
medicine
-
enzyme is the main enzymatic activity of gelatinolysis in oral squamous cell carcinomas. The enzyme form/proform ratio obtained by zymography is significantly higher in T3 and T4 stages than in T1 and T2 stages
medicine
-
only a minority of urine samples from patients with bladder cancer show enzyme activity
medicine
-
ratio of matrx metalloproteinases MMP-9/MMP-2 is enhanced in cancer patients compared with benign diseases and healthy individuals. No correlation between gelatinolytic activity and high tumoral marker values is found
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Netzel-Arnett, S.; Sang, Q.X.; Moore, W.G.I.; Navre, M.; Birkedal-Hansen, H.; van Wart, H.E.
Comparative sequence specificities of human 72- and 92-kDa gelatinases (type IV collagenases) and PUMP (matrilysin)
Biochemistry
32
6427-6432
1993
Homo sapiens
brenda
Okada, Y.; Morodomi, T.; Enghild, J.J.; Suzuki, K.; Yasui, A.; Nakanishi, I.; Salvesen, G.; Nagase, H.
Matrix metalloproteinase 2 from human rheumatoid synovial fibroblasts. Purification and activation of the precursor and enzymic properties
Eur. J. Biochem.
194
721-730
1990
Homo sapiens
brenda
Collier, I.E.; Wilhelm, S.M.; Eisen, A.Z.; Marmer, B.L.; Grant, G.A.; Seltzer, J.L.; Kronberger, A.; He, C.; Bauer, E.A.; Goldberg, G.I.
H-ras oncogene-transformed human bronchial epithelial cells (TBE-1) secrete a single metalloprotease capable of degrading basement membrane collagen
J. Biol. Chem.
263
6579-6587
1988
Homo sapiens
brenda
Nguyen, Q.; Murphy, G.; Hughes, C.E.; Mort, J.S.; Roughley, P.J.
Matrix metalloproteinases cleave at two distinct sites on human cartilage link protein
Biochem. J.
295
595-598
1993
Homo sapiens
brenda
Ochieng, J.; Fridman, R.; Nangia-Makker, P.; Kleiner, D.E.; Liotta, L.A.; Stetler-Stevenson, W.G.; Raz, A.
Galectin-3 is a novel substrate for human matrix metalloproteinases-2 and -9
Biochemistry
33
14109-14114
1994
Homo sapiens
brenda
Allan, J.A.; Docherty, A.J.P.; Barker, P.J.; Huskisson, N.S.; Reynolds, J.J.; Murphy, G.
Binding of gelatinases A and B to type-I collagen and other matrix components
Biochem. J.
309
299-306
1995
Homo sapiens
brenda
Imai, K.; Shikata, H.; Okada, Y.
Degradation of vitronectin by matrix metalloproteinases-1, -2, -3, -7 and -9
FEBS Lett.
369
249-251
1995
Homo sapiens
brenda
Fridman, R.; Bird, R.E.; Hoyhta, M.; Oelkuct, M.; Komarek, D.; Liang, C.M.; Berman, M.L.; Liotta, L.A.; Stetler-Stevenson, W.G.; Fuerst, T.R.
Expression of human recombinant 72 kDa gelatinase and tissue inhibitor of metalloproteinase-2 (TIMP-2): characterization of complex and free enzyme
Biochem. J.
289
411-416
1993
Homo sapiens
brenda
Willenbrock, F.; Crabbe, T.; Slocombe, P.M.; Sutton, C.W.; Docherty, A.J.P.; Cockett, M.I.; O'Shea, M.; Brocklehurst, K.; Phillips, I.R.; Murphy, G.
The activity of the tissue inhibitors of metalloproteinases is regulated by C-terminal domain interactions: a kinetic analysis of the inhibition of gelatinase A
Biochemistry
32
4330-4337
1993
Homo sapiens
brenda
Miyazaki, K.; Funahashi, K.; Numata, Y.; Koshikawa, N.; Akaogi, K.; Kikkawa, Y.; Yasumitsu, H.; Umeda, M.
Purification and characterization of a two-chain form of tissue inhibitor of metalloproteinases (TIMP) type 2 and a low molecular weight TIMP-like protein
J. Biol. Chem.
268
14387-14393
1993
Homo sapiens
brenda
Banyai, L.; Tordai, H.; Patthy, L.
The gelatin-binding site of human 72 kDa type IV collagenase (gelatinase A)
Biochem. J.
298
403-407
1994
Homo sapiens
brenda
Ye, Q.Z.; Johnson, L.L.; Yu, A.E.; Hupe, D.
Reconstructed 19 kDa catalytic domain of gelatinase A is an active proteinase
Biochemistry
34
4702-4708
1995
Homo sapiens
brenda
LePage, R.N.; Fosang, A.J.; Fuller, S.J.; Murphy, G.; Evin, G.; Beyreuther, K.; Masters, C.L.; Small, D.H.
Gelatinase A possesses a beta-secretase-like activity in cleaving the amyloid protein precursor of Alzheimers disease
FEBS Lett.
377
267-270
1995
Homo sapiens
brenda
Gohlke, U.; Gomis-Ruth, F.X.; Crabbe, T.; Murphy, G.; Docherty, A.J.P.; Bode, W.
The C-terminal (haemopexin-like) domain structure of human gelatinase A (MMP2): structural implications for its function
FEBS Lett.
378
126-130
1996
Homo sapiens
brenda
Libson, A.M.; Gittis, A.G.; Collier, I.E.; Marmer, B.L.; Goldberg, G.I.; Lattman, E.E.
Crystal structure of the haemopexin-like C-terminal domain of gelatinase A [letter]
Nat. Struct. Biol.
2
938-942
1995
Homo sapiens
brenda
Murphy, G.; Crabbe, T.
Gelatinases A and B
Methods Enzymol.
248
470-484
1995
Homo sapiens
brenda
Fridman, R.; Toth, M.; Pena, D.; Mobashery, S.
Activation of progelatinase B (MMP-9) by gelatinase A (MMP-2)
Cancer Res.
55
2548-2555
1995
Homo sapiens
brenda
Lee, H.J.; Chung, M.C.; Lee, C.H.; Chun, H.K.; Kho, Y.H.
Purification of progelatinase A (matrix metalloproteinase 2) and a tissue inhibitor of metalloproteinase-2 (TIMP-2) from T98G human glioblastoma cells
J. Biochem. Mol. Biol.
28
33-39
1995
Homo sapiens
-
brenda
Ochieng, J.; Warfield, P.; Green, B.
Interactions of gelatinases with soluble and immobilized fetuin and asialofetuin
Arch. Biochem. Biophys.
322
250-255
1995
Homo sapiens
brenda
Hutton, M.; Willenbrock, F.; Brocklehurst, K.; Murphy, G.
Kinetic analysis of the mechanism of interaction of full-length TIMP-2 and gelatinase A: evidence for the existence of a low-affinity intermediate
Biochemistry
37
10094-10098
1998
Homo sapiens
brenda
Feng, Y.; Likos, J.J.; Zhu, L.; Woodward, H.; Munie, G.; McDonald, J.J.; Stevens, A.M.; Howard, C.P.; De Crescenzo, G.A.; Welsch, D.; Shieh, H.S.; Stallings, W.C.
Solution structure and backbone dynamics of the catalytic domain of matrix metalloproteinase-2 complexed with a hydroxamic acid inhibitor
Biochim. Biophys. Acta
1598
10-23
2002
Homo sapiens
brenda
Gehrmann, M.; Briknarova, K.; Banyai, L.; Patthy, L.; Llinas, M.
The col-1 module of human matrix metalloproteinase-2 (MMP-2): structural/functional relatedness between gelatin-binding fibronectin type II modules and lysine-binding kringle domains
Biol. Chem.
383
137-148
2002
Homo sapiens
brenda
Collier, I.E.; Saffarian, S.; Marmer, B.L.; Elson, E.L.; Goldberg, G.
Substrate recognition by gelatinase A: the C-terminal domain facilitates surface diffusion
Biophys. J.
81
2370-2377
2001
Homo sapiens
brenda
Tordai, H.; Patthy, L.
The gelatin-binding site of the second type-II domain of gelatinase A/MMP-2
Eur. J. Biochem.
259
513-518
1999
Homo sapiens
brenda
Lee, S.J.; Jang, J.W.; Kim, Y.M.; Lee, H.I.; Jeon, J.Y.; Kwon, Y.G.; Lee, S.T.
Endostatin binds to the catalytic domain of matrix metalloproteinase-2
FEBS Lett.
519
147-152
2002
Homo sapiens
brenda
Bigg, H.F.; Shi, Y.E.; Liu, Y.E.; Steffensen, B.; Overall, C.M.
Specific, high affinity binding of tissue inhibitor of metalloproteinases-4 (TIMP-4) to the COOH-terminal hemopexin-like domain of human gelatinase A. TIMP-4 binds progelatinase A and the COOH-terminal domain in a similar manner to TIMP-2
J. Biol. Chem.
272
15496-15500
1997
Homo sapiens
brenda
Olson, M.W.; Gervasi, D.C.; Mobashery, S.; Fridman, R.
Kinetic analysis of the binding of human matrix metalloproteinase-2 and -9 to tissue inhibitor of metalloproteinase (TIMP)-1 and TIMP-2
J. Biol. Chem.
272
29975-29983
1997
Homo sapiens
brenda
Wallon, U.M.; Overall, C.M.
The hemopexin-like domain (C domain) of human gelatinase A (matrix metalloproteinase-2) requires Ca2+ for fibronectin and heparin binding. Binding properties of recombinant gelatinase A C domain to extracellular matrix and basement membrane components
J. Biol. Chem.
272
7473-7481
1997
Homo sapiens
brenda
Kleifeld, O.; Kotra, L.P.; Gervasi, D.C.; Brown, S.; Bernardo, M.M.; Fridman, R.; Mobashery, S.; Sagi, I.
X-ray absorption studies of human matrix metalloproteinase-2 (MMP-2) bound to a highly selective mechanism-based inhibitor. comparison with the latent and active forms of the enzyme
J. Biol. Chem.
276
17125-17131
2001
Homo sapiens (P08253), Homo sapiens
brenda
Chen, E.I.; Kridel, S.J.; Howard, E.W.; Li, W.; Godzik, A.; Smith, J.W.
A unique substrate recognition profile for matrix metalloproteinase-2
J. Biol. Chem.
277
4485-4491
2002
Homo sapiens
brenda
Higashi, S.; Miyazaki, K.
Identification of a region of beta-amyloid precursor protein essential for its gelatinase A inhibitory activity
J. Biol. Chem.
278
14020-14028
2003
Homo sapiens
brenda
Chen, E.I.; Li, W.; Godzik, A.; Howard, E.W.; Smith, J.W.
A residue in the S2 subsite controls substrate selectivity of matrix metalloproteinase-2 and matrix metalloproteinase-9
J. Biol. Chem.
278
17158-17163
2003
Homo sapiens (P08253)
brenda
Lauer-Fields, J.L.; Sritharan, T.; Stack, M.S.; Nagase, H.; Fields, G.B.
Selective hydrolysis of triple-helical substrates by matrix metalloproteinase-2 and -9
J. Biol. Chem.
278
18140-18145
2003
Homo sapiens
brenda
Rosenblum, G.; Meroueh, S.O.; Kleifeld, O.; Brown, S.; Singson, S.P.; Fridman, R.; Mobashery, S.; Sagi, I.
Structural basis for potent slow binding inhibition of human matrix metalloproteinase-2 (MMP-2)
J. Biol. Chem.
278
27009-27015
2003
Homo sapiens (P08253), Homo sapiens
brenda
Tamura, Y.; Watanabe, F.; Nakatani, T.; Yasui, K.; Fuji, M.; Komurasaki, T.; Tsuzuki, H.; Maekawa, R.; Yoshioka, T.; Kawada, K.; Sugita, K.; Ohtani, M.
Highly selective and orally active inhibitors of type IV collagenase (MMP-9 and MMP-2): N-sulfonylamino acid derivatives
J. Med. Chem.
41
640-649
1998
Homo sapiens
brenda
Cheng, D.; Shen, Q.; Nan, F.; Qian, Z.; Ye, Q.Z.
Purification and characterization of catalytic domains of gelatinase A with or without fibronectin insert for high-throughput inhibitor screening
Protein Expr. Purif.
27
63-74
2003
Homo sapiens
brenda
Briknarova, K.; Grishaev, A.; Banyai, L.; Tordai, H.; Patthy, L.; Llinas, M.
The second type II module from human matrix metalloproteinase 2: structure, function and dynamics
Structure
7
1235-1245
1999
Homo sapiens
brenda
Xu, X.; Chen, Z.; Wang, Y.; Yamada, Y.; Steffensen, B.
Functional basis for the overlap in ligand interactions and substrate specificities of matrix metalloproteinases-9 and -2
Biochem. J.
392
127-134
2005
Homo sapiens
brenda
Rossello, A.; Nuti, E.; Orlandini, E.; Carelli, P.; Rapposelli, S.; Macchia, M.; Minutolo, F.; Carbonaro, L.; Albini, A.; Benelli, R.; Cercignani, G.; Murphy, G.; Balsamo, A.
New N-arylsulfonyl-N-alkoxyaminoacetohydroxamic acids as selective inhibitors of gelatinase A (MMP-2)
Bioorg. Med. Chem.
12
2441-2450
2004
Homo sapiens
brenda
Kozaci, L.D.; Guner, A.; Oktay, G.; Guner, G.
Alterations in biochemical components of extracellular matrix in intervertebral disc herniation: role of MMP-2 and TIMP-2 in type II collagen loss
Cell Biochem. Funct.
24
431-436
2006
Homo sapiens
brenda
Di Carlo, A.; Terracciano, D.; Mariano, A.; Macchia, V.
Matrix metalloproteinase-2 and matrix metalloproteinase-9 type IV collagenases in serum of patients with pleural effusions
Int. J. Oncol.
26
1363-1368
2005
Homo sapiens
brenda
Khorramizadeh, M.R.; Aalizadeh, N.; Pezeshki, M.; Ghahary, A.; Zeraati, H.; Berahmeh, A.; Safa, O.; Saadat, F.
Determination of gelatinase A using a modified indirect hemagglutination assay in human prostate cancer screening and assessment of its correlation with prostate-specific antigen parameters
Int. J. Urol.
12
637-643
2005
Homo sapiens
brenda
Tam, E.M.; Moore, T.R.; Butler, G.S.; Overall, C.M.
Characterization of the distinct collagen binding, helicase and cleavage mechanisms of matrix metalloproteinase 2 and 14 (gelatinase A and MT1-MMP): the differential roles of the MMP hemopexin c domains and the MMP-2 fibronectin type II modules in collage
J. Biol. Chem.
279
43336-43344
2004
Homo sapiens
brenda
Gehrmann, M.L.; Douglas, J.T.; Banyai, L.; Tordai, H.; Patthy, L.; Llinas, M.
Modular autonomy, ligand specificity, and functional cooperativity of the three in-tandem fibronectin type II repeats from human matrix metalloproteinase 2
J. Biol. Chem.
279
46921-46929
2004
Homo sapiens
brenda
Kato, K.; Hara, A.; Kuno, T.; Kitaori, N.; Huilan, Z.; Mori, H.; Toida, M.; Shibata, T.
Matrix metalloproteinases 2 and 9 in oral squamous cell carcinomas: manifestation and localization of their activity
J. Cancer Res. Clin. Oncol.
131
340-346
2005
Homo sapiens
brenda
Ikejiri, M.; Bernardo, M.M.; Meroueh, S.O.; Brown, S.; Chang, M.; Fridman, R.; Mobashery, S.
Design, synthesis, and evaluation of a mechanism-based inhibitor for gelatinase A
J. Org. Chem.
70
5709-5712
2005
Homo sapiens
brenda
Xu, X.; Wang, Y.; Lauer-Fields, J.L.; Fields, G.B.; Steffensen, B.
Contributions of the MMP-2 collagen binding domain to gelatin cleavage. Substrate binding via the collagen binding domain is required for hydrolysis of gelatin but not short peptides
Matrix Biol.
23
171-181
2004
Homo sapiens
brenda
Di Carlo, A.; Terracciano, D.; Mariano, A.; Macchia, V.
Urinary gelatinase activities (matrix metalloproteinases 2 and 9) in human bladder tumors
Oncol. Rep.
15
1321-1326
2006
Homo sapiens
brenda
Monaco, S.; Gioia, M.; Rodriguez, J.; Fasciglione, G.F.; Di Pierro, D.; Lupidi, G.; Krippahl, L.; Marini, S.; Coletta, M.
Modulation of the proteolytic activity of matrix metalloproteinase-2 (gelatinase A) on fibrinogen
Biochem. J.
402
503-513
2007
Homo sapiens
brenda
Xu, X.; Chen, Z.; Wang, Y.; Bonewald, L.; Steffensen, B.
Inhibition of MMP-2 gelatinolysis by targeting exodomain-substrate interactions
Biochem. J.
406
147-155
2007
Homo sapiens
brenda
Moroy, G.; Denhez, C.; El Mourabit, H.; Toribio, A.; Dassonville, A.; Decarme, M.; Renault, J.H.; Mirand, C.; Bellon, G.; Sapi, J.; Alix, A.J.; Hornebeck, W.; Bourguet, E.
Simultaneous presence of unsaturation and long alkyl chain at P1 of Ilomastat confers selectivity for gelatinase A (MMP-2) over gelatinase B (MMP-9) inhibition as shown by molecular modelling studies
Bioorg. Med. Chem.
15
4753-4766
2007
Homo sapiens
brenda
Falcinelli, E.; Giannini, S.; Boschetti, E.; Gresele, P.
Platelets release active matrix metalloproteinase-2 in vivo in humans at a site of vascular injury: lack of inhibition by aspirin
Br. J. Haematol.
138
221-230
2007
Homo sapiens
brenda
Emara, M.; Cheung, P.Y.
Inhibition of sulfur compounds and antioxidants on MMP-2 and -9 at the activity level found during neonatal hypoxia-reoxygenation
Eur. J. Pharmacol.
544
168-173
2006
Homo sapiens, Sus scrofa
brenda
Hwang, E.S.; Lee, H.J.
Allyl isothiocyanate and its N-acetylcysteine conjugate suppress metastasis via inhibition of invasion, migration, and matrix metalloproteinase-2/-9 activities in SK-Hep 1 human hepatoma cells
Exp. Biol. Med. (Maywood)
231
421-430
2006
Homo sapiens
brenda
Sariahmetoglu, M.; Crawford, B.D.; Leon, H.; Sawicka, J.; Li, L.; Ballermann, B.J.; Holmes, C.; Berthiaume, L.G.; Holt, A.; Sawicki, G.; Schulz, R.
Regulation of matrix metalloproteinase-2 (MMP-2) activity by phosphorylation
FASEB J.
21
2486-2495
2007
Homo sapiens (P08253)
brenda
Kim, M.M.; Kim, S.K.
Chitooligosaccharides inhibit activation and expression of matrix metalloproteinase-2 in human dermal fibroblasts
FEBS Lett.
580
2661-2666
2006
Homo sapiens
brenda
Bogusiewicz, M.; Stryjecka-Zimmer, M.; Postawski, K.; Jakimiuk, A.J.; Rechberger, T.
Activity of matrix metalloproteinase-2 and -9 and contents of their tissue inhibitors in uterine leiomyoma and corresponding myometrium
Gynecol. Endocrinol.
23
541-546
2007
Homo sapiens
brenda
Strek, M.; Gorlach, S.; Podsedek, A.; Sosnowska, D.; Koziolkiewicz, M.; Hrabec, Z.; Hrabec, E.
Procyanidin oligomers from Japanese quince (Chaenomeles japonica) fruit inhibit activity of MMP-2 and MMP-9 metalloproteinases
J. Agric. Food Chem.
55
6447-6452
2007
Homo sapiens
brenda
Higashi, S.; Miyazaki, K.
Identification of amino acid residues of the matrix metalloproteinase-2 essential for its selective inhibition by beta-amyloid precursor protein-derived inhibitor
J. Biol. Chem.
283
10068-10078
2008
Homo sapiens
brenda
Mazzoni, A.; Mannello, F.; Tay, F.R.; Tonti, G.A.; Papa, S.; Mazzotti, G.; Di Lenarda, R.; Pashley, D.H.; Breschi, L.
Zymographic analysis and characterization of MMP-2 and -9 forms in human sound dentin
J. Dent. Res.
86
436-440
2007
Homo sapiens
brenda
Gao, L.; Kang, L.; Chen, Q.; Chen, C.; Xu, B.; Jiang, S.
Advanced glycation end products inhibit production and activity of matrix metalloproteinase-2 in human umbilical vein endothelial cells
J. Int. Med. Res.
35
709-715
2007
Homo sapiens
brenda
Rutges, J.; Kummer, J.; Oner, F.; Verbout, A.; Castelein, R.; Roestenburg, H.; Dhert, W.; Creemers, L.
Increased MMP-2 activity during intervertebral disc degeneration is correlated to MMP-14 levels
J. Pathol.
214
523-530
2008
Homo sapiens
brenda
Robinet, A.; Emonard, H.; Banyai, L.; Laronze, J.Y.; Patthy, L.; Hornebeck, W.; Bellon, G.
Collagen-binding domains of gelatinase A and thrombospondin-derived peptides impede endocytic clearance of active gelatinase A and promote HT1080 fibrosarcoma cell invasion
Life Sci.
82
376-382
2008
Homo sapiens
brenda
Whitlock, G.A.; Dack. K.N.; Dickinson, R.P.; Lewis M.L
A novel series of highly selective inhibitors of MMP-3
Bioorg. Med. Chem. Lett.
17
6750-6753
2007
Homo sapiens
brenda
Tao, P.; Fisher, J.F.; Shi, Q.; Vreven, T.; Mobashery, S.; Schlegel, H.B.
Matrix metalloproteinase 2 inhibition: combined quantum mechanics and molecular mechanics studies of the inhibition mechanism of (4-phenoxyphenylsulfonyl)methylthiirane and its oxirane analogue
Biochemistry
48
9839-9847
2009
Homo sapiens
brenda
Lisboa, R.A.; Lisboa, F.A.; de Castro Santos, G.; Andrade, M.V.; Cunha-Melo, J.R.
Matrix metalloproteinase 2 activity decreases in human periodontal ligament fibroblast cultures submitted to simulated orthodontic force
In Vitro Cell. Dev. Biol. Anim.
45
614-621
2009
Homo sapiens
brenda
Sato, Y.; Kishi, J.; Suzuki, K.; Nakamura, H.; Hayakawa, T.
Sonic extracts from a bacterium related to periapical disease activate gelatinase A and inactivate tissue inhibitor of metalloproteinases TIMP-1 and TIMP-2
Int. Endod. J.
42
1104-1111
2009
Homo sapiens
brenda
Momi, S.; Falcinelli, E.; Giannini, S.; Ruggeri, L.; Cecchetti, L.; Corazzi, T.; Libert, C.; Gresele, P.
Loss of matrix metalloproteinase 2 in platelets reduces arterial thrombosis in vivo
J. Exp. Med.
206
2365-2379
2009
Homo sapiens
brenda
Marquez-Aguirre, A.; Sandoval-Rodriguez, A.; Gonzalez-Cuevas, J.; Bueno-Topete, M.; Navarro-Partida, J.; Arellano-Olivera, I.; Lucano-Landeros, S.; Armendariz-Borunda, J.
Adenoviral delivery of dominant-negative transforming growth factor beta type II receptor up-regulates transcriptional repressor SKI-like oncogene, decreases matrix metalloproteinase 2 in hepatic stellate cell and prevents liver fibrosis in rats
J. Gene Med.
11
207-219
2009
Homo sapiens
brenda
Akers, W.J.; Xu, B.; Lee, H.; Sudlow, G.; Fields, G.B.; Achilefu, S.; Edwards, W.B.
Detection of MMP-2 and MMP-9 activity in vivo with a triple-helical peptide optical probe
Bioconjug. Chem.
23
656-663
2012
Homo sapiens
brenda
Koo, B.H.; Han, J.H.; Yeom, Y.I.; Kim, D.S.
Thrombin-dependent MMP-2 activity is regulated by heparan sulfate
J. Biol. Chem.
285
41270-41279
2010
Homo sapiens
brenda
Zhang, R.; Pan, X.; Huang, Z.; Weber, G.F.; Zhang, G.
Osteopontin enhances the expression and activity of MMP-2 via the SDF-1/CXCR4 axis in hepatocellular carcinoma cell lines
PLoS ONE
6
e23831
2011
Homo sapiens
brenda
Diaz, N.; Suarez, D.; Suarez, E.
Kinetic and binding effects in peptide substrate selectivity of matrix metalloproteinase-2: molecular dynamics and QM/MM calculations
Proteins
78
1-11
2010
Homo sapiens
brenda
Kawagoe, M.; Tsuruga, E.; Oka, K.; Sawa, Y.; Ishikawa, H.
Matrix metalloproteinase-2 degrades fibrillin-1 and fibrillin-2 of oxytalan fibers in the human eye and periodontal ligaments in vitro
Acta Histochem. Cytochem.
46
153-159
2013
Homo sapiens (P08253), Homo sapiens
brenda
Musumeci, G.; Magro, G.; Cardile, V.; Coco, M.; Marzagalli, R.; Castrogiovanni, P.; Imbesi, R.; Graziano, A.; Barone, F.; Di Rosa, M.; Castorina, S.; Castorina, A.
Characterization of matrix metalloproteinase-2 and -9, ADAM-10 and N-cadherin expression in human glioblastoma multiforme
Cell Tissue Res.
362
45-60
2015
Homo sapiens (P08253), Homo sapiens
brenda
Koo, B.; Kim, Y.; Han, J.; Kim, D.
Dimerization of matrix metalloproteinase-2 (MMP-2): functional implication in MMP-2 activation
J. Biol. Chem.
287
22643-22653
2012
Homo sapiens (P08253)
brenda
Higashi, S.; Hirose, T.; Takeuchi, T.; Miyazaki, K.
Molecular design of a highly selective and strong protein inhibitor against matrix metalloproteinase-2 (MMP-2)
J. Biol. Chem.
288
9066-9076
2013
Homo sapiens (P08253)
brenda
Goncalves, A.; Meschiari, C.; Stetler-Stevenson, W.; Nonato, M.; Alves, C.; Espreafico, E.; Gerlach, R.
Expression of soluble and functional full-length human matrix metalloproteinase-2 in Escherichia coli
J. Biotechnol.
157
20-24
2012
Homo sapiens (P08253), Homo sapiens
brenda
Ren, X.; Lamb, G.D.; Murphy, R.M.
Distribution and activation of matrix metalloproteinase-2 in skeletal muscle fibers
Am. J. Physiol. Cell Physiol.
317
C613-C625
2019
Homo sapiens (P08253), Homo sapiens, Rattus norvegicus (P33436)
brenda
Nejima, D.; Zarkouna, Y.; Pujol, P.; Gammoudi, A.; Boussen, H.; Manai, M.
Clinicopathologic and prognostic significance of gelatinase A in Tunisian colorectal cancer a case-control study
Appl. Immunohistochem. Mol. Morphol.
25
64-70
2017
Homo sapiens (P08253), Homo sapiens
brenda
Henriet, P.; Emonard, H.
Matrix metalloproteinase-2 not (just) a hero of the past
Biochimie
166
223-232
2019
Homo sapiens (P08253)
brenda
Nishihama, K.; Yasuma, T.; Yano, Y.; D Alessandro-Gabazza, C.N.; Toda, M.; Hinneh, J.A.; Baffour Tonto, P.; Takeshita, A.; Totoki, T.; Mifuji-Moroka, R.; Kobayashi, T.; Iwasa, M.; Takei, Y.; Morser, J.; Cann, I.; Gabazza, E.C.
Anti-apoptotic activity of human matrix metalloproteinase-2 attenuates diabetes mellitus
Metab. Clin. Exp.
82
88-99
2018
Homo sapiens (P08253), Homo sapiens
brenda
Baez, I.B.; Sampieri, C.L.; Solano, F.C.; Martinez Cazares, M.T.; Montero, H.; Cuevas, R.Z.
Activity of matrix metalloproteinase 2 and 9 isoforms in sputum samples from individuals infected with M. tuberculosis
Microb. Pathog.
135
103607
2019
Homo sapiens (P08253), Homo sapiens
brenda
Abu Bakar, A.R.; Ripen, A.M.; Merican, A.F.; Mohamad, S.B.
Enzymatic inhibitory activity of Ficus deltoidea leaf extract on matrix metalloproteinase-2, 8 and 9
Nat. Prod. Res.
33
1765-1768
2019
Homo sapiens (P08253)
brenda
Jana, S.; Chatterjee, K.; Ray, A.K.; DasMahapatra, P.; Swarnakar, S.
Regulation of matrix metalloproteinase-2 activity by COX-2-PGE2-pAKT axis promotes angiogenesis in endometriosis
PLoS ONE
11
e0163540
2016
Homo sapiens (P08253), Homo sapiens
brenda
Nicolai, E.; Sinibaldi, F.; Sannino, G.; Lagana, G.; Basoli, F.; Licoccia, S.; Cozza, P.; Santucci, R.; Piro, M.C.
Omega-3 and omega-6 fatty acids act as inhibitors of the matrix metalloproteinase-2 and matrix metalloproteinase-9 activity
Protein J.
36
278-285
2017
Homo sapiens (P08253)
brenda
EXTERNAL LINKS (specific for EC-Number 3.4.24.24)
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
About BRENDA
Social media
Help
Survey
Download
Contribution
Legal
Curated at
Member of
