Information on EC 3.4.24.16 - neurolysin

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Specify your search results
Mark a special word or phrase in this record:
Select one or more organisms in this record:
Show additional data
Do not include text mining results
Include (text mining) results (more...)
Include results (AMENDA + additional results, but less precise; more...)


The expected taxonomic range for this enzyme is: Eutheria

EC NUMBER
COMMENTARY
3.4.24.16
-
RECOMMENDED NAME
GeneOntology No.
neurolysin
-
REACTION
REACTION DIAGRAM
COMMENTARY
ORGANISM
UNIPROT ACCESSION NO.
LITERATURE
Preferential cleavage in neurotensin: Pro10-/-Tyr
show the reaction diagram
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
hydrolysis of peptide bond
-
-
endopeptidase; peptides, endopeptidase
-
SYNONYMS
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
endopeptidase 24.16
-
-
-
-
endopeptidase 24.16
-
-
endopeptidase 24.16B
-
-
-
-
EP24.16c
-
the cytosolic/membrane bound enzyme form
EP24.16m
-
the mitochondrial enzyme form
MEP
-
-
-
-
Microsomal endopeptidase
-
-
-
-
Microsomal endopeptidase
-
-
neurolisin
-
-
neurolysin
-
-
neurotensin endopeptidase
-
-
-
-
oligopeptidase M
-
-
-
-
oligopeptidase M
-
-
peptidase, neurotensin endo
-
-
-
-
peptidase, neurotensin endo-
-
-
-
-
SABP
-
-
-
-
soluble angiotensin II-binding protein
-
-
Soluble angiotensin-binding protein
-
-
-
-
thimet oligopeptidase II
-
neurolysin is most likely to be confused with thimet oligopeptidase II, but it is distinguished by its lack of activation by thiol compounds, inhibition by millimolar concentrations of Pro-Ile, cleavage of neurotensin at the Pro-Tyr bond, and different mobility in column chromatography
thimet peptidase II
-
-
ep24.16
-
-
ep24.16
additional information
-
-
MOP
-
-
-
-
additional information
-
neurolysin belongs to the M3 metallopeptidase family
additional information
-
the enzyme belongs to the M3A family
additional information
-
the enzyme belongs to the zinc-dependent peptidases of the metallopeptidase M3 family
CAS REGISTRY NUMBER
COMMENTARY
149371-24-4
-
90463-53-9
-