Reference on EC 3.4.23.B19 - plasmepsin V
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Klemba, M.; Goldberg, D.E.
Characterization of plasmepsin V, a membrane-bound aspartic protease homolog in the endoplasmic reticulum of Plasmodium falciparum.
Mol. Biochem. Parasitol.
143
183-191
2005
Plasmodium falciparum
Russo, I.; Babbitt, S.; Muralidharan, V.; Butler, T.; Oksman, A.; Goldberg, D.E.
Plasmepsin V licenses Plasmodium proteins for export into the host erythrocyte
Nature
463
632-636
2010
Plasmodium falciparum
Boddey, J.A.; Hodder, A.N.; Guenther, S.; Gilson, P.R.; Patsiouras, H.; Kapp, E.A.; Pearce, J.A.; de Koning-Ward, T.F.; Simpson, R.J.; Crabb, B.S.; Cowman, A.F.
An aspartyl protease directs malaria effector proteins to the host cell
Nature
463
627-631
2010
Plasmodium falciparum
Sittikul, P.; Songtawee, N.; Kongkathip, N.; Boonyalai, N.
In vitro and in silico studies of naphthoquinones and peptidomimetics toward Plasmodium falciparum plasmepsin V
Biochimie
152
159-173
2018
Plasmodium falciparum (Q8I6Z5), Plasmodium falciparum
Gazdik, M.; Jarman, K.E.; ONeill, M.T.; Hodder, A.N.; Lowes, K.N.; Jousset Sabroux, H.; Cowman, A.F.; Boddey, J.A.; Sleebs, B.E.
Exploration of the P3 region of PEXEL peptidomimetics leads to a potent inhibitor of the Plasmodium protease, plasmepsin V
Bioorg. Med. Chem.
24
1993-2010
2016
Plasmodium falciparum (Q8I6Z5)
Meissner, K.A.; Kronenberger, T.; Maltarollo, V.G.; Trossini, G.H.G.; Wrenger, C.
Targeting the Plasmodium falciparum plasmepsin V by ligand-based virtual screening
Chem. Biol. Drug Des.
93
300-312
2019
Plasmodium falciparum (Q8I6Z5), Plasmodium falciparum
Boonyalai, N.; Sittikul, P.; Yuvaniyama, J.
Plasmodium falciparum plasmepsin V (PfPMV) Insights into recombinant expression, substrate specificity and active site structure
Mol. Biochem. Parasitol.
201
5-15
2015
Plasmodium falciparum (Q8I6Z5), Plasmodium falciparum
Sappakhaw, K.; Takasila, R.; Sittikul, P.; Wattana-Amorn, P.; Assavalapsakul, W.; Boonyalai, N.
Biochemical characterization of plasmepsin V from Plasmodium vivax Thailand isolates Substrate specificity and enzyme inhibition
Mol. Biochem. Parasitol.
204
51-63
2015
Plasmodium vivax (A0A0H4FQ60), Plasmodium vivax, Plasmodium vivax Thai (A0A0H4FQ60)
Loymunkong, C.; Sittikul, P.; Songtawee, N.; Wongpanya, R.; Boonyalai, N.
Yield improvement and enzymatic dissection of Plasmodium falciparum plasmepsin V
Mol. Biochem. Parasitol.
231
111188
2019
Plasmodium falciparum (Q8I6Z5), Plasmodium falciparum
L, M.; Soliman, M.E.
The binding landscape of plasmepsin V and the implications for flap dynamics
Mol. Biosyst.
12
1457-1467
2016
Plasmodium vivax
Marapana, D.S.; Dagley, L.F.; Sandow, J.J.; Nebl, T.; Triglia, T.; Pasternak, M.; Dickerman, B.K.; Crabb, B.S.; Gilson, P.R.; Webb, A.I.; Boddey, J.A.; Cowman, A.F.
Plasmepsin V cleaves malaria effector proteins in a distinct endoplasmic reticulum translocation interactome for export to the erythrocyte
Nat. Microbiol.
3
1010-1022
2018
Plasmodium falciparum (Q8I6Z5), Plasmodium falciparum
Hodder, A.N.; Sleebs, B.E.; Czabotar, P.E.; Gazdik, M.; Xu, Y.; ONeill, M.T.; Lopaticki, S.; Nebl, T.; Triglia, T.; Smith, B.J.; Lowes, K.; Boddey, J.A.; Cowman, A.F.
Structural basis for plasmepsin V inhibition that blocks export of malaria proteins to human erythrocytes
Nat. Struct. Mol. Biol.
22
590-596
2015
Plasmodium vivax (Q6PRR9), Plasmodium vivax, Plasmodium falciparum (Q8I6Z5), Plasmodium falciparum
Tarr, S.J.; Osborne, A.R.
Experimental determination of the membrane topology of the Plasmodium protease plasmepsin V
PLoS ONE
10
e0121786
2015
Plasmodium falciparum (Q8I6Z5), Plasmodium falciparum
Boonyalai, N.; Collins, C.R.; Hackett, F.; Withers-Martinez, C.; Blackman, M.J.
Essentiality of Plasmodium falciparum plasmepsin V
PLoS ONE
13
e0207621
2018
Plasmodium falciparum (Q8I6Z5), Plasmodium falciparum
McGillewie, L.; Soliman, M.E.
Flap flexibility amongst plasmepsins I, II, III, IV, and V Sequence, structural, and molecular dynamics analyses
Proteins
83
1693-1705
2015
Plasmodium falciparum (Q8I6Z5), Plasmodium falciparum
Bedi, R.K.; Patel, C.; Mishra, V.; Xiao, H.; Yada, R.Y.; Bhaumik, P.
Understanding the structural basis of substrate recognition by Plasmodium falciparum plasmepsin V to aid in the design of potent inhibitors
Sci. Rep.
6
31420
2016
Plasmodium falciparum (Q8I6Z5), Plasmodium falciparum
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