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Reference on EC 3.4.22.B71 - SENP2 peptidase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Itahana, Y.; Yeh, E.T.; Zhang, Y.
Nucleocytoplasmic shuttling modulates activity and ubiquitination-dependent turnover of SUMO-specific protease 2
Mol. Cell. Biol.
26
4675-4689
2006
Homo sapiens (Q9HC62)
Manually annotated by BRENDA team
Reverter, D.; Lima, C.D.
Structural basis for SENP2 protease interactions with SUMO precursors and conjugated substrates
Nat. Struct. Mol. Biol.
13
1060-1068
2006
Homo sapiens (Q9HC62)
Manually annotated by BRENDA team
Jiang, M.; Chiu, S.Y.; Hsu, W.
SUMO-specific protease 2 in Mdm2-mediated regulation of p53
Cell Death Differ.
18
1005-1015
2011
Mus musculus
Manually annotated by BRENDA team
Ban, R.; Nishida, T.; Urano, T.
Mitotic kinase Aurora-B is regulated by SUMO-2/3 conjugation/deconjugation during mitosis
Genes Cells
16
652-669
2011
Homo sapiens
Manually annotated by BRENDA team
Hang, J.; Dasso, M.
Association of the human SUMO-1 protease SENP2 with the nuclear pore
J. Biol. Chem.
277
19961-19966
2002
Homo sapiens (Q9HC62)
Manually annotated by BRENDA team
Mikolajczyk, J.; Drag, M.; Bekes, M.; Cao, J.T.; Ronai, Z.; Salvesen, G.S.
Small ubiquitin-related modifier (SUMO)-specific proteases: profiling the specificities and activities of human SENPs
J. Biol. Chem.
282
26217-26224
2007
Homo sapiens
Manually annotated by BRENDA team
Chung, S.S.; Ahn, B.Y.; Kim, M.; Choi, H.H.; Park, H.S.; Kang, S.; Park, S.G.; Kim, Y.B.; Cho, Y.M.; Lee, H.K.; Chung, C.H.; Park, K.S.
Control of adipogenesis by the SUMO-specific protease SENP2
Mol. Cell. Biol.
30
2135-2146
2010
Mus musculus (Q91ZX6)
Manually annotated by BRENDA team
Kang, X.; Qi, Y.; Zuo, Y.; Wang, Q.; Zou, Y.; Schwartz, R.J.; Cheng, J.; Yeh, E.T.
SUMO-specific protease 2 is essential for suppression of polycomb group protein-mediated gene silencing during embryonic development
Mol. Cell
38
191-201
2010
Mus musculus (Q91ZX6)
Manually annotated by BRENDA team
Chiu, S.Y.; Asai, N.; Costantini, F.; Hsu, W.
SUMO-specific protease 2 is essential for modulating p53-Mdm2 in development of trophoblast stem cell niches and lineages
PLoS Biol.
6
e310
2008
Mus musculus
Manually annotated by BRENDA team
Reverter, D.; Lima, C.D.
A basis for SUMO protease specificity provided by analysis of human Senp2 and a Senp2-SUMO complex
Structure
12
1519-1531
2004
Homo sapiens (Q9HC62)
Manually annotated by BRENDA team
Tan, M.Y.; Mu, X.Y.; Liu, B.; Wang, Y.; Bao, E.D.; Qiu, J.X.; Fan, Y.
SUMO-specific protease 2 suppresses cell migration and invasion through inhibiting the expression of MMP13 in bladder cancer cells
Cell. Physiol. Biochem.
32
542-548
2013
Homo sapiens
Manually annotated by BRENDA team
Koo, Y.D.; Choi, J.W.; Kim, M.; Chae, S.; Ahn, B.Y.; Kim, M.; Oh, B.C.; Hwang, D.; Seol, J.H.; Kim, Y.B.; Park, Y.J.; Chung, S.S.; Park, K.S.
SUMO-specific protease 2 (SENP2) is an important regulator of fatty acid metabolism in skeletal muscle
Diabetes
64
2420-2431
2015
Mus musculus
Manually annotated by BRENDA team
Qi, Y.; Zuo, Y.; Yeh, E.T.; Cheng, J.
An essential role of small ubiquitin-like modifier (SUMO)-specific protease 2 in myostatin expression and myogenesis
J. Biol. Chem.
289
3288-3293
2014
Mus musculus, Mus musculus C57BL/6
Manually annotated by BRENDA team
Cubenas-Potts, C.; Goeres, J.D.; Matunis, M.J.
SENP1 and SENP2 affect spatial and temporal control of sumoylation in mitosis
Mol. Biol. Cell
24
3483-3495
2013
Homo sapiens (Q9HC62)
Manually annotated by BRENDA team
Chow, K.H.; Elgort, S.; Dasso, M.; Powers, M.A.; Ullman, K.S.
The SUMO proteases SENP1 and SENP2 play a critical role in nucleoporin homeostasis and nuclear pore complex function
Mol. Biol. Cell
25
160-168
2014
Homo sapiens
Manually annotated by BRENDA team
Lu, H.; Liu, B.; You, S.; Chen, L.; Dongmei, Q.; Gu, M.; Lu, Y.; Chen, Y.; Zhang, F.; Yu, B.
SENP2 regulates MEF2A de-SUMOylation in an activity dependent manner
Mol. Biol. Rep.
40
2485-2490
2013
Homo sapiens
Manually annotated by BRENDA team
Chow, K.H.; Elgort, S.; Dasso, M.; Ullman, K.S.
Two distinct sites in Nup153 mediate interaction with the SUMO proteases SENP1 and SENP2
Nucleus
3
349-358
2012
Homo sapiens
Manually annotated by BRENDA team
Tang, S.; Huang, G.; Tong, X.; Xu, L.; Cai, R.; Li, J.; Zhou, X.; Song, S.; Huang, C.; Cheng, J.
Role of SUMO-specific protease 2 in reprogramming cellular glucose metabolism
PLoS ONE
8
e63965
2013
Homo sapiens, Mus musculus
Manually annotated by BRENDA team
Alegre, K.O.; Reverter, D.
Structural insights into the SENP6 loop1 structure in complex with SUMO2
Protein Sci.
23
433-441
2014
Homo sapiens (Q9HC62)
Manually annotated by BRENDA team
Pei, H.; Chen, L.; Liao, Q.M.; Wang, K.J.; Chen, S.G.; Liu, Z.J.; Zhang, Z.C.
SUMO-specific protease 2 (SENP2) functions as a tumor suppressor in osteosarcoma via SOX9 degradation
Exp. Ther. Med.
16
5359-5365
2018
Homo sapiens
Manually annotated by BRENDA team
Zheng, Q.; Cao, Y.; Chen, Y.; Wang, J.; Fan, Q.; Huang, X.; Wang, Y.; Wang, T.; Wang, X.; Ma, J.; Cheng, J.
Senp2 regulates adipose lipid storage by de-SUMOylation of Setdb1
J. Mol. Cell Biol.
10
258-266
2018
Mus musculus (Q91ZX6)
Manually annotated by BRENDA team
Koo, Y.D.; Lee, J.S.; Lee, S.A.; Quaresma, P.G.F.; Bhat, R.; Haynes, W.G.; Park, Y.J.; Kim, Y.B.; Chung, S.S.; Park, K.S.
SUMO-specific protease 2 mediates leptin-induced fatty acid oxidation in skeletal muscle
Metab. Clin. Exp.
95
27-35
2019
Mus musculus (Q91ZX6)
Manually annotated by BRENDA team
Tan, M.; Zhang, D.; Zhang, E.; Xu, D.; Liu, Z.; Qiu, J.; Fan, Y.; Shen, B.
SENP2 suppresses epithelial-mesenchymal transition of bladder cancer cells through deSUMOylation of TGF-betaRI
Mol. Carcinog.
56
2332-2341
2017
Homo sapiens (Q9HC62)
Manually annotated by BRENDA team
Tan, M.; Gong, H.; Wang, J.; Tao, L.; Xu, D.; Bao, E.; Liu, Z.; Qiu, J.
SENP2 regulates MMP13 expression in a bladder cancer cell line through SUMOylation of TBL1/TBLR1
Sci. Rep.
5
13996
2015
Homo sapiens (Q9HC62)
Manually annotated by BRENDA team
Maruyama, E.O.; Lin, H.; Chiu, S.Y.; Yu, H.M.; Porter, G.A.; Hsu, W.
Extraembryonic but not embryonic SUMO-specific protease 2 is required for heart development
Sci. Rep.
6
20999
2016
Mus musculus (Q91ZX6)
Manually annotated by BRENDA team
Chang, C.C.; Huang, Y.S.; Lin, Y.M.; Lin, C.J.; Jeng, J.C.; Liu, S.M.; Ho, T.L.; Chang, R.T.; Changou, C.A.; Ho, C.C.; Shih, H.M.
The role of sentrin-specific protease 2 substrate recognition in TGF-beta-induced tumorigenesis
Sci. Rep.
8
9786
2018
Homo sapiens (Q9HC62)
Manually annotated by BRENDA team