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Information on EC 3.4.22.B35 - calpain 15 and Organism(s) Drosophila melanogaster and UniProt Accession P27398

for references in articles please use BRENDA:EC3.4.22.B35
preliminary BRENDA-supplied EC number
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EC Tree
     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.22 Cysteine endopeptidases
                3.4.22.B35 calpain 15
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This record set is specific for:
Drosophila melanogaster
UNIPROT: P27398
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The taxonomic range for the selected organisms is: Drosophila melanogaster
The enzyme appears in selected viruses and cellular organisms
Reaction Schemes
broad endopeptidase specificity
Synonyms
capn15, sol calpain, calpain 15, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
small optic lobes protein
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CAS REGISTRY NUMBER
COMMENTARY hide
78990-62-2
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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
peptide + H2O
hydrolyzed peptide
show the reaction diagram
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-
-
?
additional information
?
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mutations in the small optic lobes gene cause specific cells to degenerate in the developing optic lobes, resulting in the absence of certain classes of columnar neurons
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?
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
additional information
?
-
-
mutations in the small optic lobes gene cause specific cells to degenerate in the developing optic lobes, resulting in the absence of certain classes of columnar neurons
-
-
?
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
CAND_DROME
1594
0
174313
Swiss-Prot
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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Boeckmann, B.; Bairoch, A.; Apweiler, R.; Blatter, M.C.; Estreicher, A.; Gasteiger, E.; Martin M.J.; Michoud, K.; O'Donovan, C.; Phan, I.; Pilbout, S.; Schneider, M.
The SWISS-PROT protein knowledgebase and its supplement TrEMBL
Nucleic Acids Res.
31
365-370
2003
Drosophila melanogaster (P27398)
Manually annotated by BRENDA team
Delaney, S.J.; Hayward, D.C.; Barleben, F.; Fischback, K.F.; Miklos, G.L.G.
Molecular cloning and analysis of small optic lobes, a structural brain gene of Drosophila melanogaster
Proc. Natl. Acad. Sci. USA
88
7214-7218
1991
Drosophila melanogaster
Manually annotated by BRENDA team