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Information on EC 3.4.22.B14 - papain-like proteinase 1 and Organism(s) Porcine epidemic diarrhea virus and UniProt Accession P0C6Y4

for references in articles please use BRENDA:EC3.4.22.B14
preliminary BRENDA-supplied EC number
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EC Tree
     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.22 Cysteine endopeptidases
                3.4.22.B14 papain-like proteinase 1
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This record set is specific for:
Porcine epidemic diarrhea virus
UNIPROT: P0C6Y4
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Word Map
The taxonomic range for the selected organisms is: Porcine epidemic diarrhea virus
The enzyme appears in selected viruses and cellular organisms
Reaction Schemes
papain-like proteinase 1 is responsible for cleavages located at the N-terminus of the replicase polyprotein
Synonyms
plp-1, pl1pro, replicase polyprotein 1a, plp1 proteinase, papain-like proteinase 1, first papain-like cysteine proteinase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
C16.001
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mouse hepatitis virus papain-like proteinase 1
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PL1-PRO
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PLP-1
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PLP1
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
hydrolysis of peptide bond
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Sulea, T.; Lindner, H.A.; Purisima, E.O.; Mnard, R.
Binding site-based classification of coronaviral papain-like proteases
Proteins Struct. Funct. Bioinform.
62
760-775
2006
bovine coronavirus (P0C6W7), bovine coronavirus Ent (P0C6W7), Human coronavirus 229E (P0C6X1), infectious bronchitis virus (P0C6V3), infectious bronchitis virus Beaudette (P0C6V3), Murine hepatitis virus (P0C6V0), Murine hepatitis virus A59 (P0C6V0), porcine epidemic diarrhea virus (P0C6Y4), Severe acute respiratory syndrome-related coronavirus (P0C6X7), Severe acute respiratory syndrome-related coronavirus, Transmissible gastroenteritis virus (P0C6V2)
Manually annotated by BRENDA team