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Acquired Immunodeficiency Syndrome
Caspase-11 contributes to pulmonary host defense against Klebsiella pneumoniae and local activation of coagulation.
Acute Kidney Injury
Caspase-11 Mediates Pyroptosis of Tubular Epithelial Cells and Septic Acute Kidney Injury.
Acute Kidney Injury
Caspase-11-mediated tubular epithelial pyroptosis underlies contrast-induced acute kidney injury.
Acute Kidney Injury
The cleavage of gasdermin D by caspase-11 promotes tubular epithelial cell pyroptosis and urinary IL-18 excretion in acute kidney injury.
Acute Lung Injury
Caspase-11-mediated endothelial pyroptosis underlies endotoxemia-induced lung injury.
Acute Lung Injury
Mechanical Ventilation Exacerbates Poly (I:C) Induced Acute Lung Injury: Central Role for Caspase-11 and Gut-Lung Axis.
Adenocarcinoma of Lung
Caspase-11 and AIM2 inflammasome are involved in smoking-induced COPD and lung adenocarcinoma.
Amyotrophic Lateral Sclerosis
Dissociation between neurodegeneration and caspase-11-mediated activation of caspase-1 and caspase-3 in a mouse model of amyotrophic lateral sclerosis.
Arthritis
Matrix metalloproteinase 8 deficiency in mice exacerbates inflammatory arthritis through delayed neutrophil apoptosis and reduced caspase 11 expression.
Arthritis, Gouty
Caspase-11 Mediates Neutrophil Chemotaxis and Extracellular Trap Formation During Acute Gouty Arthritis Through Alteration of Cofilin Phosphorylation.
Asthma
Caspase-11 promotes allergic airway inflammation.
Autoimmune Diseases
Pyroptosis by caspase-11 inflammasome-Gasdermin D pathway in autoimmune diseases.
Bacterial Infections
Bacterial recognition pathways that lead to inflammasome activation.
Bacterial Infections
Caspase-11 promotes the fusion of phagosomes harboring pathogenic bacteria with lysosomes by modulating actin polymerization.
Bacterial Infections
Caspase-11-dependent pyroptosis of lung epithelial cells protects from melioidosis while caspase-1 mediates macrophage pyroptosis and production of IL-18.
Bacterial Infections
Caspase-11: arming the guards against bacterial infection.
Bacterial Infections
Caspases as the Key Effectors of Inflammatory Responses Against Bacterial Infection.
Bacterial Infections
Guanylate-binding proteins at the crossroad of noncanonical inflammasome activation during bacterial infections.
Bacterial Infections
Hierarchical cell-type-specific functions of caspase-11 in LPS shock and antibacterial host defense.
Bacterial Infections
Inflammatory caspases are innate immune receptors for intracellular LPS.
Bacterial Infections
Non-canonical inflammasome activation targets caspase-11.
Bacterial Infections
Scutellarin inhibits caspase-11 activation and pyroptosis in macrophages via regulating PKA signaling.
Bacterial Infections
TRIF signaling is required for caspase-11-dependent immune responses and lethality in sepsis.
Bacterial Infections
Type 1 interferon aggravates lipopolysaccharide-induced sepsis through upregulating Caspase-11 and Gasdermin D.
Brain Edema
Ac-FLTD-CMK inhibits pyroptosis and exerts neuroprotective effect in a mice model of traumatic brain injury.
Brain Ischemia
Caspases determine the vulnerability of oligodendrocytes in the ischemic brain.
Breast Neoplasms
MicroRNA-191, an estrogen responsive microRNA, functions as an oncogenic regulator in human breast cancer.
Brucellosis
Caspases-1 and caspase-11 mediate pyroptosis, inflammation, and control of Brucella joint infection.
Brucellosis
Guanylate-binding protein 5 licenses caspase-11 for Gasdermin-D mediated host resistance to Brucella abortus infection.
Carcinogenesis
Caspase-11 attenuates gastrointestinal inflammation and experimental colitis pathogenesis.
Carcinogenesis
Caspase-11 regulates the tumour suppressor function of STAT1 in a murine model of colitis-associated carcinogenesis.
Carcinogenesis
Gene expression profiling of biological pathway alterations by radiation exposure.
Carcinogenesis
Identification of a novel subpopulation of Caspase-4 positive non-small cell lung Cancer patients.
Carcinoma
Expression analysis of the human caspase-1 subfamily reveals specific regulation of the CASP5 gene by lipopolysaccharide and interferon-gamma.
Carcinoma
The loss of CASP4 expression is associated with poor prognosis in esophageal squamous cell carcinoma.
caspase-11 deficiency
An Inactivating Caspase-11 Passenger Mutation Originating from the 129 Murine Strain in Mice Targeted for c-Iap1.
caspase-11 deficiency
Caspase-11 Contributes to Oviduct Pathology during Genital Chlamydia Infection in Mice.
caspase-11 deficiency
Caspase-11 deficiency impairs neutrophil recruitment and bacterial clearance in the early stage of pulmonary Klebsiella pneumoniae infection.
caspase-11 deficiency
Caspase-11 Modulates Inflammation and Attenuates Toxoplasma gondii Pathogenesis.
caspase-11 deficiency
Caspase-11 Plays a Protective Role in Pulmonary Acinetobacter baumannii Infection.
caspase-11 deficiency
Caspase-11 regulates cell migration by promoting Aip1-Cofilin-mediated actin depolymerization.
caspase-11 deficiency
Caspase-11 signaling enhances graft-versus-host disease.
caspase-11 deficiency
Caspase-11-dependent IL-1? release boosts Th17 immunity against Paracoccidioides brasiliensis.
Cataract
Role of short-wavelength blue light in the formation of cataracts and the expression of caspase-1, caspase-11, Gasdermin D in rat lens epithelial cells: insights into a novel pathogenic mmechanism of cataracts.
Chlamydia Infections
Caspase-11 Contributes to Oviduct Pathology during Genital Chlamydia Infection in Mice.
Colitis
Caspase-11 attenuates gastrointestinal inflammation and experimental colitis pathogenesis.
Colitis
Caspase-11 is expressed in the colonic mucosa and protects against dextran sodium sulfate-induced colitis.
Colitis
Caspase-11 regulates the tumour suppressor function of STAT1 in a murine model of colitis-associated carcinogenesis.
Colitis
Defective Intestinal Mucin-Type O-Glycosylation Causes Spontaneous Colitis-Associated Cancer in Mice.
Colitis
Environmental Factors Modify the Severity of Acute DSS Colitis in Caspase-11-Deficient Mice.
Colitis
Gut Microbiota Affects Sensitivity to Acute DSS-induced Colitis Independently of Host Genotype.
Colitis
Microbiota Normalization Reveals that Canonical Caspase-1 Activation Exacerbates Chemically Induced Intestinal Inflammation.
Colitis
Positive role of CCAAT/enhancer-binding protein homologous protein, a transcription factor involved in the endoplasmic reticulum stress response in the development of colitis.
Colitis
Protective role for caspase-11 during acute experimental murine colitis.
Colitis, Ulcerative
Correction to: Inhibition of C3a/C3aR Axis in Diverse Stages of Ulcerative Colitis Affected the Prognosis of UC by Modulating the Pyroptosis and Expression of Caspase-11.
Colitis, Ulcerative
Inhibition of C3a/C3aR Axis in Diverse Stages of Ulcerative Colitis Affected the Prognosis of UC by Modulating the Pyroptosis and Expression of Caspase-11.
Colonic Neoplasms
Secretoglobin 3A2 eliminates human cancer cells through pyroptosis.
Colorectal Neoplasms
Caspase-11 regulates the tumour suppressor function of STAT1 in a murine model of colitis-associated carcinogenesis.
Cysts
Caspase-11 Modulates Inflammation and Attenuates Toxoplasma gondii Pathogenesis.
Demyelinating Diseases
Caspase-11 mediates oligodendrocyte cell death and pathogenesis of autoimmune-mediated demyelination.
Ehrlichiosis
Interferon Type I Regulates Inflammasome Activation and High Mobility Group Box 1 Translocation in Hepatocytes During Ehrlichia-Induced Acute Liver Injury.
Endotoxemia
An 8-Hydroxy-Quinoline Derivative Protects Against Lipopolysaccharide-Induced Lethality in Endotoxemia by Inhibiting HMGB1-Mediated Caspase-11 Signaling.
Endotoxemia
Caspase-11-mediated endothelial pyroptosis underlies endotoxemia-induced lung injury.
Endotoxemia
Cytoplasmic LPS activates caspase-11: implications in TLR4-independent endotoxic shock.
Endotoxemia
Differential roles of caspase-1 and caspase-11 in infection and inflammation.
Endotoxemia
Hierarchical cell-type-specific functions of caspase-11 in LPS shock and antibacterial host defense.
Endotoxemia
The Endotoxin Delivery Protein HMGB1 Mediates Caspase-11-Dependent Lethality in Sepsis.
Endotoxemia
TRIF signaling is required for caspase-11-dependent immune responses and lethality in sepsis.
Escherichia coli Infections
cAMP metabolism controls caspase-11 inflammasome activation and pyroptosis in sepsis.
Esophageal Squamous Cell Carcinoma
The loss of CASP4 expression is associated with poor prognosis in esophageal squamous cell carcinoma.
Fatty Liver
Caspase-11-Mediated Hepatocytic Pyroptosis Promotes the Progression of Nonalcoholic Steatohepatitis.
Gastrointestinal Stromal Tumors
Mutational analysis of CASP1, 2, 3, 4, 5, 6, 7, 8, 9, 10, and 14 genes in gastrointestinal stromal tumors.
Glioma
Essential role of caspase-11 in activation-induced cell death of rat astrocytes.
Gout
Caspase-11 Mediates Neutrophil Chemotaxis and Extracellular Trap Formation During Acute Gouty Arthritis Through Alteration of Cofilin Phosphorylation.
Graft vs Host Disease
Author Correction: Caspase-11 signaling enhances graft-versus-host disease.
Graft vs Host Disease
Caspase-11 signaling enhances graft-versus-host disease.
Gram-Negative Bacterial Infections
Bacterial Outer Membrane Vesicles Mediate Cytosolic Localization of LPS and Caspase-11 Activation.
Gram-Negative Bacterial Infections
Dangerous Liaisons: Caspase-11 and Reactive Oxygen Species Crosstalk in Pathogen Elimination.
Gram-Negative Bacterial Infections
TRIF Licenses Caspase-11-Dependent NLRP3 Inflammasome Activation by Gram-Negative Bacteria.
Hyperalgesia
Soluble epoxide hydrolase inhibitor trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl)urea prevents hyperalgesia through regulating NLRC4 inflammasome-related pro-inflammatory and anti-inflammatory signaling pathways in the lipopolysaccharide-induced pain mouse model.
Hypertension
Identification of Target Genes in Hypertension and Left Ventricular Remodeling.
Infections
cAMP metabolism controls caspase-11 inflammasome activation and pyroptosis in sepsis.
Infections
Canonical Inflammasomes Drive IFN-? to Prime Caspase-11 in Defense against a Cytosol-Invasive Bacterium.
Infections
Caspase-1 but Not Caspase-11 Is Required for NLRC4-Mediated Pyroptosis and Restriction of Infection by Flagellated Legionella Species in Mouse Macrophages and In Vivo.
Infections
Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases.
Infections
Caspase-11 and caspase-1 differentially modulate actin polymerization via RhoA and Slingshot proteins to promote bacterial clearance.
Infections
Caspase-11 auto-proteolysis is crucial for noncanonical inflammasome activation.
Infections
Caspase-11 Contributes to Oviduct Pathology during Genital Chlamydia Infection in Mice.
Infections
Caspase-11 deficiency impairs neutrophil recruitment and bacterial clearance in the early stage of pulmonary Klebsiella pneumoniae infection.
Infections
Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1.
Infections
Caspase-11 Modulates Inflammation and Attenuates Toxoplasma gondii Pathogenesis.
Infections
Caspase-11 Plays a Protective Role in Pulmonary Acinetobacter baumannii Infection.
Infections
Caspase-11 promotes the fusion of phagosomes harboring pathogenic bacteria with lysosomes by modulating actin polymerization.
Infections
Caspase-11-dependent IL-1? release boosts Th17 immunity against Paracoccidioides brasiliensis.
Infections
Caspase-11-dependent pyroptosis of lung epithelial cells protects from melioidosis while caspase-1 mediates macrophage pyroptosis and production of IL-18.
Infections
Caspases as the Key Effectors of Inflammatory Responses Against Bacterial Infection.
Infections
Caspases-1 and caspase-11 mediate pyroptosis, inflammation, and control of Brucella joint infection.
Infections
Detection of cytosolic bacteria by inflammatory caspases.
Infections
Differential roles of caspase-1 and caspase-11 in infection and inflammation.
Infections
Flightless-I regulates proinflammatory caspases by selectively modulating intracellular localization and caspase activity.
Infections
Guanylate-binding protein 5 licenses caspase-11 for Gasdermin-D mediated host resistance to Brucella abortus infection.
Infections
Hierarchical cell-type-specific functions of caspase-11 in LPS shock and antibacterial host defense.
Infections
Inflammasome components caspase-1 and adaptor protein apoptosis-associated speck-like proteins are important in resistance to Cryptosporidium parvum.
Infections
Interferon Type I Regulates Inflammasome Activation and High Mobility Group Box 1 Translocation in Hepatocytes During Ehrlichia-Induced Acute Liver Injury.
Infections
Interferon-inducible guanylate-binding proteins at the interface of cell-autonomous immunity and inflammasome activation.
Infections
Leishmania Lipophosphoglycan Triggers Caspase-11 and the Non-canonical Activation of the NLRP3 Inflammasome.
Infections
Neutrophil Caspase-11 Is Essential to Defend against a Cytosol-Invasive Bacterium.
Infections
Neutrophil Caspase-11 Is Required for Cleavage of Caspase-1 and Secretion of IL-1? in Aspergillus fumigatus Infection.
Infections
Reactive oxygen species regulate caspase-11 expression and activation of the non-canonical NLRP3 inflammasome during enteric pathogen infection.
Infections
Regulation, Activation and Function of Caspase-11 during Health and Disease.
Infections
Role of Canonical and Non-canonical Inflammasomes During Burkholderia Infection.
Infections
SERPINB1-mediated checkpoint of inflammatory caspase activation.
Infections
The NLRP6 Inflammasome Recognizes Lipoteichoic Acid and Regulates Gram-Positive Pathogen Infection.
Infections
Type I interferon contributes to noncanonical inflammasome activation, mediates immunopathology, and impairs protective immunity during fatal infection with lipopolysaccharide-negative ehrlichiae.
Insulin Resistance
Caspase-12, but Not Caspase-11, Inhibits Obesity and Insulin Resistance.
Insulin Resistance
Maternal high-fat diet exaggerates diet-induced insulin resistance in adult offspring by enhancing inflammasome activation through noncanonical pathway of caspase-11.
Keratitis
Regulatory effect of caspase-11 on interleukin-1? in the fungal keratitis.
Keratitis
Wedelolactone ameliorates Pseudomonas aeruginosa-induced inflammation and corneal injury by suppressing caspase-4/5/11/GSDMD-mediated non-canonical pyroptosis.
Kidney Diseases
Caspase-11 promotes NLRP3 inflammasome activation via the cleavage of pannexin1 in acute kidney disease.
Kidney Neoplasms
Prognostic autophagy model based on CASP4 and BIRC5 expression in patients with renal cancer: independent datasets-based study.
Lung Injury
cGAS promotes sepsis in radiotherapy of cancer by up-regulating caspase-11 signaling.
Lung Injury
Luteolin activates Tregs to promote IL-10 expression and alleviating caspase-11-dependent pyroptosis in sepsis-induced lung injury.
Melanoma
Caspase-11 Noncanonical Inflammasome: A Novel Key Player in Murine Models of Neuroinflammation and Multiple Sclerosis.
Melanoma
Emerging Activators and Regulators of Inflammasomes and Pyroptosis.
Melanoma
The ketone metabolite ?-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease.
Melioidosis
Caspase-11-dependent pyroptosis of lung epithelial cells protects from melioidosis while caspase-1 mediates macrophage pyroptosis and production of IL-18.
Mouth Neoplasms
LOH at PDCD4, CTNNB1, and CASP4 loci contributes to stage progression of oral cancer.
Mucositis
Caspase-11 is not necessary for chemotherapy-induced intestinal mucositis.
Multiple Sclerosis
Caspase-11 Noncanonical Inflammasome: A Novel Key Player in Murine Models of Neuroinflammation and Multiple Sclerosis.
Mycoses
Regulatory effect of caspase-11 on interleukin-1? in the fungal keratitis.
Myocardial Ischemia
p38 mitogen activated protein kinase mediates both death signaling and functional depression in the heart.
Neoplasms
Apoptosis signal-regulating kinase 1 regulates the expression of caspase-11.
Neoplasms
Apoptosis-associated genes related to photodynamic therapy in breast carcinomas.
Neoplasms
Baicalin protects against zearalenone-induced chicks liver and kidney injury by inhibiting expression of oxidative stress, inflammatory cytokines and caspase signaling pathway.
Neoplasms
CASP4 gene silencing in epithelial cancer cells leads to impairment of cell migration, cell-matrix adhesion and tissue invasion.
Neoplasms
Caspase 4 Overexpression as a Prognostic Marker in Clear Cell Renal Cell Carcinoma: A Study Based on the Cancer Genome Atlas Data Mining.
Neoplasms
Caspase-11 regulates the tumour suppressor function of STAT1 in a murine model of colitis-associated carcinogenesis.
Neoplasms
Caspase-11 signaling enhances graft-versus-host disease.
Neoplasms
cGAS promotes sepsis in radiotherapy of cancer by up-regulating caspase-11 signaling.
Neoplasms
Defective Intestinal Mucin-Type O-Glycosylation Causes Spontaneous Colitis-Associated Cancer in Mice.
Neoplasms
Essential role of caspase-11 in activation-induced cell death of rat astrocytes.
Neoplasms
Gene expression profiling of paired ovarian tumors obtained prior to and following adjuvant chemotherapy: molecular signatures of chemoresistant tumors.
Neoplasms
Identification of a novel subpopulation of Caspase-4 positive non-small cell lung Cancer patients.
Neoplasms
Induction of caspase-11 by inflammatory stimuli in rat astrocytes: lipopolysaccharide induction through p38 mitogen-activated protein kinase pathway.
Neoplasms
Inflammasome expression is higher in ovarian tumors than in normal ovary.
Neoplasms
MicroRNA overexpression increases cortical neuronal vulnerability to injury.
Neoplasms
Mutational analysis of CASP1, 2, 3, 4, 5, 6, 7, 8, 9, 10, and 14 genes in gastrointestinal stromal tumors.
Neoplasms
p38 mitogen activated protein kinase mediates both death signaling and functional depression in the heart.
Neoplasms
Regulation of the expression of tumor necrosis factor?related genes by abnormal histone H3K27 acetylation: Implications for neural tube defects.
Neoplasms
Rhubarb-Aconite Decoction (RAD) Drug-Containing Serum Alleviated Endotoxin-Induced Oxidative Stress Injury and Inflammatory Response in Caco-2 Cells In Vitro.
Neuroinflammatory Diseases
Alteration in the differentiation-related molecular expression in the subventricular zone in a mouse model of Parkinson's disease.
Neuroinflammatory Diseases
Caspase-11 Modulates Inflammation and Attenuates Toxoplasma gondii Pathogenesis.
Neuroinflammatory Diseases
Caspase-11 Noncanonical Inflammasome: A Novel Key Player in Murine Models of Neuroinflammation and Multiple Sclerosis.
Neuroinflammatory Diseases
Toll-Like Receptor 4 Mediates Methamphetamine-Induced Neuroinflammation through Caspase-11 Signaling Pathway in Astrocytes.
neutrophil collagenase deficiency
Matrix metalloproteinase 8 deficiency in mice exacerbates inflammatory arthritis through delayed neutrophil apoptosis and reduced caspase 11 expression.
Obesity
Caspase-12, but Not Caspase-11, Inhibits Obesity and Insulin Resistance.
Ovarian Neoplasms
Estrogen-regulated gene expression predicts response to endocrine therapy in patients with ovarian cancer.
Parkinson Disease
Caspase-11 mediates inflammatory dopaminergic cell death in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease.
Peripheral Nerve Injuries
Nlrp6 promotes recovery after peripheral nerve injury independently of inflammasomes.
Pneumonia
Caspase-11 contributes to pulmonary host defense against Klebsiella pneumoniae and local activation of coagulation.
Pneumonia, Pneumococcal
ASC and NLRP3 maintain innate immune homeostasis in the airway through an inflammasome-independent mechanism.
Pulmonary Disease, Chronic Obstructive
Caspase-11 and AIM2 inflammasome are involved in smoking-induced COPD and lung adenocarcinoma.
Reperfusion Injury
Ischemia-reperfusion induces renal tubule pyroptosis via the CHOP-caspase-11 pathway.
Salmonella Infections
Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1.
Salmonella Infections
Salmonella infection induces recruitment of Caspase-8 to the inflammasome to modulate IL-1? production.
Sepsis
A Rapid Caspase-11 Response Induced by IFN? Priming Is Independent of Guanylate Binding Proteins.
Sepsis
A role for stefin B (cystatin B) in inflammation and endotoxemia.
Sepsis
A small molecule binding HMGB1 inhibits caspase-11-mediated lethality in sepsis.
Sepsis
AGER-Mediated Lipid Peroxidation Drives Caspase-11 Inflammasome Activation in Sepsis.
Sepsis
An 8-Hydroxy-Quinoline Derivative Protects Against Lipopolysaccharide-Induced Lethality in Endotoxemia by Inhibiting HMGB1-Mediated Caspase-11 Signaling.
Sepsis
An inactivating caspase-11 passenger mutation muddles sepsis research.
Sepsis
Antecedent Dietary Glutamine Supplementation Benefits Modulation of Liver Pyroptosis in Mice with Polymicrobial Sepsis.
Sepsis
Bacterial Outer Membrane Vesicles Mediate Cytosolic Localization of LPS and Caspase-11 Activation.
Sepsis
cAMP metabolism controls caspase-11 inflammasome activation and pyroptosis in sepsis.
Sepsis
Caspase-11 contributes to pulmonary host defense against Klebsiella pneumoniae and local activation of coagulation.
Sepsis
Caspase-11 Mediates Pyroptosis of Tubular Epithelial Cells and Septic Acute Kidney Injury.
Sepsis
Caspase-11 Non-canonical Inflammasomes in the Lung.
Sepsis
Caspase-11 Requires the Pannexin-1 Channel and the Purinergic P2X7 Pore to Mediate Pyroptosis and Endotoxic Shock.
Sepsis
Caspase-8 Collaborates with Caspase-11 to Drive Tissue Damage and Execution of Endotoxic Shock.
Sepsis
cGAS promotes sepsis in radiotherapy of cancer by up-regulating caspase-11 signaling.
Sepsis
Complement pathway amplifies caspase-11-dependent cell death and endotoxin-induced sepsis severity.
Sepsis
Cystatin C Deficiency Increases LPS-Induced Sepsis and NLRP3 Inflammasome Activation in Mice.
Sepsis
Dynamin-related Irgm proteins modulate LPS-induced caspase-11 activation and septic shock.
Sepsis
Heparin prevents caspase-11-dependent septic lethality independent of anticoagulant properties.
Sepsis
Hierarchical cell-type-specific functions of caspase-11 in LPS shock and antibacterial host defense.
Sepsis
Human caspase-4 detects tetra-acylated LPS and cytosolic Francisella and functions differently from murine caspase-11.
Sepsis
Inflammasome Activation by Bacterial Outer Membrane Vesicles Requires Guanylate Binding Proteins.
Sepsis
Interferon Type I Regulates Inflammasome Activation and High Mobility Group Box 1 Translocation in Hepatocytes During Ehrlichia-Induced Acute Liver Injury.
Sepsis
Lipid Peroxidation Drives Gasdermin D-Mediated Pyroptosis in Lethal Polymicrobial Sepsis.
Sepsis
Matrix Metalloproteinase Triple-Helical Peptide Inhibitors: Potential Cross-Reactivity with Caspase-11.
Sepsis
Role of Gate-16 and Gabarap in Prevention of Caspase-11-Dependent Excess Inflammation and Lethal Endotoxic Shock.
Sepsis
Sphingosine-1-phosphate Receptor 2 Signaling Promotes Caspase-11-dependent Macrophage Pyroptosis and Worsens Escherichia coli Sepsis Outcome.
Sepsis
The Role of Stefin B in Neuro-inflammation.
Sepsis
TRIF signaling is required for caspase-11-dependent immune responses and lethality in sepsis.
Sepsis
Type 1 interferon aggravates lipopolysaccharide-induced sepsis through upregulating Caspase-11 and Gasdermin D.
Sepsis
Upregulation of Mitochondrial Redox Sensitive Proteins in LPS-Treated Stefin B-Deficient Macrophages.
Shock, Septic
Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling.
Shock, Septic
Distinct downstream pathways of caspase-11 in regulating apoptosis and cytokine maturation during septic shock response.
Shock, Septic
Dynamin-related Irgm proteins modulate LPS-induced caspase-11 activation and septic shock.
Shock, Septic
Identification and characterization of Ich-3, a member of the interleukin-1beta converting enzyme (ICE)/Ced-3 family and an upstream regulator of ICE.
Shock, Septic
Neurotoxic effects of lipopolysaccharide on nigral dopaminergic neurons are mediated by microglial activation, interleukin-1beta, and expression of caspase-11 in mice.
Shock, Septic
Novel perspectives on non-canonical inflammasome activation.
Shock, Septic
Pyroptotic and non-pyroptotic effector functions of caspase-11.
Shock, Septic
Role of Gate-16 and Gabarap in Prevention of Caspase-11-Dependent Excess Inflammation and Lethal Endotoxic Shock.
Shock, Septic
The oxidized phospholipid oxPAPC protects from septic shock by targeting the non-canonical inflammasome in macrophages.
Shock, Septic
Toll Like Receptor 4 Signaling Licenses the Cytosolic Transport of Lipopolysaccharide from Bacterial Outer Membrane Vesicles.
Shock, Septic
Zebrafish GSDMEb Cleavage-Gated Pyroptosis Drives Septic-Acute Kidney Injury In Vivo.
Stomach Neoplasms
Prognostic significance of mRNA expression of CASPs in gastric cancer.
Thrombosis
Inflammasome activation promotes venous thrombosis through pyroptosis.
Toxoplasmosis
Caspase-11 Modulates Inflammation and Attenuates Toxoplasma gondii Pathogenesis.
Venous Thrombosis
Inflammasome activation promotes venous thrombosis through pyroptosis.
Whooping Cough
Canonical and Non-canonical Inflammasome Activation by Outer Membrane Vesicles Derived From Bordetella pertussis.
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3.4.22.64 caspase-11
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The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable). 
