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Acquired Immunodeficiency Syndrome
Caspase-9-dependent pathway to murine germ cell apoptosis: mediation by oxidative stress, BAX, and caspase 2.
Acute Kidney Injury
Protective Effect of Taurine on Mice with Doxorubicin-induced Acute Kidney Injury.
Adenocarcinoma
Activity of selenium on cell proliferation, cytotoxicity, and apoptosis and on the expression of CASP9, BCL-XL and APC in intestinal adenocarcinoma cells.
Adenocarcinoma
Annona muricata silver nanoparticles exhibit strong anticancer activities against cervical and prostate adenocarcinomas through regulation of CASP9 and the CXCL1/CXCR2 genes axis.
Adenocarcinoma
Cancer gene therapy with iCaspase-9 transcriptionally targeted to tumor endothelial cells.
Adenocarcinoma
Cytotoxic and Antimicrobial Evaluations of Novel Apoptotic and Anti-Angiogenic Spiro Cyclic 2-Oxindole Derivatives of 2-Amino-tetrahydroquinolin-5-one.
Adenocarcinoma
Cytotoxic Mechanism of Sphaerodactylomelol, an Uncommon Bromoditerpene Isolated from Sphaerococcus coronopifolius.
Adenocarcinoma
Dysregulated Expression of Apoptosis-Associated Genes and MicroRNAs and Their Involvement in Gastric Carcinogenesis.
Adenocarcinoma
Expression analysis of caspase-6, caspase-9 and BNIP3 in prostate cancer.
Adenocarcinoma
Immune clearance gastric carcinoma cells in ascites by activating caspase-9-induced apoptosis.
Adenocarcinoma
Immunohistochemical analysis of cell death pathways in gastrointestinal adenocarcinoma.
Adenocarcinoma
Protein expression differences between lung adenocarcinoma and squamous cell carcinoma with brain metastasis.
Adenocarcinoma
[Changes in the number of copies of genetic loci in gastric cancer].
Adenocarcinoma of Lung
De novo ceramide regulates the alternative splicing of caspase 9 and Bcl-x in A549 lung adenocarcinoma cells. Dependence on protein phosphatase-1.
Adenocarcinoma of Lung
Immunocytochemical expression of a panel of markers in pleural effusions from patients with primary lung adenocarcinoma.
Adenocarcinoma of Lung
Mutational analysis of proapoptotic caspase-9 gene in common human carcinomas.
Adenocarcinoma of Lung
Resveratrol induces apoptosis via a Bak-mediated intrinsic pathway in human lung adenocarcinoma cells.
Adenocarcinoma of Lung
The JNK inhibitor SP600125 enhances dihydroartemisinin-induced apoptosis by accelerating Bax translocation into mitochondria in human lung adenocarcinoma cells.
Aggressive Periodontitis
The role of caspase-8, caspase-9, and apoptosis inducing factor in periodontal disease.
Alopecia
Tetrahydroxystilbene Glucoside Effectively Prevents Apoptosis Induced Hair Loss.
Altitude Sickness
[Studies on apoptosis and caspase-8 and caspase-9 expressions of bone marrow cells in chronic mountain sickness].
Alzheimer Disease
A second cytotoxic proteolytic peptide derived from amyloid beta-protein precursor.
Alzheimer Disease
Caspase-9 activation and caspase cleavage of tau in the Alzheimer's disease brain.
Alzheimer Disease
The silent information regulator 1 pathway attenuates ROS-induced oxidative stress in Alzheimer's disease.
Alzheimer Disease
[Neuroprotective effect of ginsenoside Rb-1 on a rat model of Alzheimer's disease].
Ameloblastoma
Detection of mitochondria-mediated apoptosis signaling molecules in ameloblastomas.
Amyotrophic Lateral Sclerosis
Identification and verification of key genes in varicocele rats through high-throughput sequencing and bioinformatics analysis.
Amyotrophic Lateral Sclerosis
MAPT (Tau) expression is a biomarker for an increased rate of survival in pediatric neuroblastoma.
Amyotrophic Lateral Sclerosis
Serum caspase-9 levels are increased in patients with amyotrophic lateral sclerosis.
Anemia
Caspase-9 is required for normal hematopoietic development and protection from alkylator-induced DNA damage in mice.
Aneurysm
Down-regulation of apoptosis after left ventricular aneurysm repair.
Aneurysm
Intrinsic Pathway-Mediated Apoptosis in Elastase-Induced Aneurysms in Rabbits.
Aneurysm
The protective effect of puerarin on angiotensin II-induced aortic aneurysm formation by the inhibition of NADPH oxidase activation and oxidative stress-triggered AP-1 signaling pathways.
Arteritis
The equine arteritis virus induces apoptosis via caspase-8 and mitochondria-dependent caspase-9 activation.
Asthma
Activation of Bcl-2-Caspase-9 Apoptosis Pathway in the Testis of Asthmatic Mice.
Astrocytoma
CASP9 Germline Mutation in a Family with Multiple Brain Tumors.
Astrocytoma
The role of caspases 9 and 9-short (9S) in death ligand- and drug-induced apoptosis in human astrocytoma cells.
Ataxia
Investigation of the Anticancer Mechanism of Isoorientin Isolated from Eremurus Spectabilis Leaves via Cell Cycle Pathways in HT-29 Human Colorectal Adenocarcinoma Cells.
Ataxia Telangiectasia
A Novel Oral Astaxanthin Nanoemulsion from Haematococcus pluvialis Induces Apoptosis in Lung Metastatic Melanoma.
Ataxia Telangiectasia
Cyto-/genotoxic effect of CdSe/ZnS quantum dots in human lung adenocarcinoma cells for potential photodynamic UV therapy applications.
Ataxia Telangiectasia
Epigenetic inactivation of BCL6B, a novel functional tumour suppressor for gastric cancer, is associated with poor survival of gastric cancer.
Ataxia Telangiectasia
Ionizing radiation-induced apoptosis in ataxia-telangiectasia fibroblasts. Roles of caspase-9 and cellular inhibitor of apoptosis protein-1.
Ataxia Telangiectasia
Preclinical evaluation of a novel SIRT1 modulator SRT1720 in multiple myeloma cells.
Ataxia Telangiectasia
Tannic Acid Induces the Mitochondrial Pathway of Apoptosis and S Phase Arrest in Porcine Intestinal IPEC-J2 Cells.
Ataxia Telangiectasia
Tetrandrine Enhances H2O2-Induced Apoptotic Cell Death Through Caspase-dependent Pathway in Human Keratinocytes.
Atherosclerosis
Caspase-9: A Multimodal Therapeutic Target With Diverse Cellular Expression in Human Disease.
Atherosclerosis
Disocin prevents postmenopausal atherosclerosis in ovariectomized LDLR-/- mice through a PGC-1?/ER? pathway leading to promotion of autophagy and inhibition of oxidative stress, inflammation and apoptosis.
Atherosclerosis
Inhibitory Effects of Ginsenoside Rb1 on Early Atherosclerosis in ApoE-/- Mice via Inhibition of Apoptosis and Enhancing Autophagy.
Atherosclerosis
Quantitative analysis of the expression of caspase 3 and caspase 9 in different types of atherosclerotic lesions in the human aorta.
Atrial Fibrillation
Mitochondrial apoptotic pathway activation in the atria of heart failure patients due to mitral and tricuspid regurgitation.
Autoimmune Diseases
An inducible caspase 9 safety switch can halt cell therapy-induced autoimmune disease.
Autoimmune Diseases
Caspase-9: A Multimodal Therapeutic Target With Diverse Cellular Expression in Human Disease.
Autoimmune Lymphoproliferative Syndrome
ER stress induces caspase-8 activation, stimulating cytochrome c release and caspase-9 activation.
Autoimmune Lymphoproliferative Syndrome
The autoimmune conundrum in common variable immunodeficiency disorders.
Bacterial Infections
Glucose-6-phosphate dehydrogenase (G6PD)-deficient epithelial cells are less tolerant to infection by Staphylococcus aureus.
Bacterial Infections
Lrcasp9 shares similarity in structural motifs with human caspase-9 and is activated following bacterial infection and anti-viral vaccination.
Blast Crisis
Effects of the bcr/abl kinase inhibitors AG957 and NSC 680410 on chronic myelogenous leukemia cells in vitro.
Bone Resorption
Bone morphogenetic protein-9 activates Smad and ERK pathways and supports human osteoclast function and survival in vitro.
Bone Resorption
Radiation alters osteoclastogenesis by regulating the cytoskeleton and lytic enzymes in RAW 264.7 cells and mouse bone marrow-derived macrophages.
Brain Edema
Protein expression differences between lung adenocarcinoma and squamous cell carcinoma with brain metastasis.
Brain Edema
Reduction of Autophagosome Overload Attenuates Neuronal Cell Death After Traumatic Brain Injury.
Brain Injuries
Caspase-9 inhibition after focal cerebral ischemia improves outcome following reversible focal ischemia.
Brain Injuries
Caspase-9.
Brain Injuries
Formation of the Apaf-1/cytochrome c complex precedes activation of caspase-9 during seizure-induced neuronal death.
Brain Injuries
Inhibiting caspase-9 after injury reduces hypoxic ischemic neuronal injury in the cortex in the newborn rat.
Brain Injuries
Mitochondrial impairment in the developing brain after hypoxia-ischemia.
Brain Injuries
Neuroprotection against hypoxic-ischemic brain injury by inhibiting the apoptotic protease activating factor-1 pathway.
Brain Injuries
Treatment of hypoxic-ischemic brain injury in newborn rats with TPCK 3 h after hypoxia decreases caspase-9 activation and improves neuropathologic outcome.
Brain Injuries
[The expression of Smac and XIAP in rat hippocampus following limbic seizure induced by kainic acid injection into amygdaloid nucleus]
Brain Injuries, Traumatic
Detectable levels of cytochrome C and activated caspase-9 in cerebrospinal fluid after human traumatic brain injury.
Brain Injuries, Traumatic
Pathways leading to apoptotic neurodegeneration following trauma to the developing rat brain.
Brain Ischemia
Analysis of Caspase-9 protein and microRNAs miR-21, miR-126 and miR-155 related to the apoptosis mechanism in the cerebellum of rats submitted to focal cerebral ischemia associated with an alcoholism model.
Brain Ischemia
Caspase-9 inhibition after focal cerebral ischemia improves outcome following reversible focal ischemia.
Brain Ischemia
Interaction between XIAP and Smac/DIABLO in the mouse brain after transient focal cerebral ischemia.
Brain Ischemia
Manganese Superoxide Dismutase Affects Cytochrome c Release and Caspase-9 Activation After Transient Focal Cerebral Ischemia in Mice.
Brain Ischemia
PDZ1 inhibitor peptide protects neurons against ischemia via inhibiting GluK2-PSD-95-module-mediated Fas signaling pathway.
Brain Ischemia
Release of caspase-9 from mitochondria during neuronal apoptosis and cerebral ischemia.
Brain Ischemia
The effect of low-energy laser irradiation on apoptotic factors following experimentally induced transient cerebral ischemia.
Brain Ischemia
[Effect of electroacupuncture on caspase-9 expression in hippocampus and neuroethology in hyperlipemia rats with concurrent cerebral ischemia]
Brain Neoplasms
CASP9 Germline Mutation in a Family with Multiple Brain Tumors.
Brain Neoplasms
Role of Caspase-9 Gene Ex5+32 G>A (rs1052576) Variant in Susceptibility to Primary Brain Tumors.
Breast Neoplasms
2-aryl benzimidazole conjugate induced apoptosis in human breast cancer MCF-7 cells through caspase independent pathway.
Breast Neoplasms
Adenosine and deoxyadenosine induces apoptosis in oestrogen receptor-positive and -negative human breast cancer cells via the intrinsic pathway.
Breast Neoplasms
Adenovirus-mediated p53 and ING4 gene co?transfer elicits synergistic antitumor effects through enhancement of p53 acetylation in breast cancer.
Breast Neoplasms
Angiotensin II suppresses adriamycin-induced apoptosis through activation of phosphatidylinositol 3-kinase/Akt signaling in human breast cancer cells.
Breast Neoplasms
Anti-miR-203 Upregulates SOCS3 Expression in Breast Cancer Cells and Enhances Cisplatin Chemosensitivity.
Breast Neoplasms
Anticancer activities of pterostilbene-isothiocyanate conjugate in breast cancer cells: involvement of PPAR?.
Breast Neoplasms
Apoptosis Cell Death Effect of Scrophularia Variegata on Breast Cancer Cells via Mitochondrial Intrinsic Pathway.
Breast Neoplasms
Apoptosis-inducing and antiproliferative effect by inhibition of miR-182-5p through the regulation of CASP9 expression in human breast cancer.
Breast Neoplasms
Apoptotic effect of noscapine in breast cancer cell lines.
Breast Neoplasms
Application of constrained aza-valine analogs for Smac mimicry.
Breast Neoplasms
Artesunate, as a HSP70 ATPase activity inhibitor, induces apoptosis in breast cancer cells.
Breast Neoplasms
Association of LncRNA-GACAT3 with MRI features of breast cancer and its molecular mechanism.
Breast Neoplasms
Cancer-selective death of human breast cancer cells by leelamine is mediated by bax and bak activation.
Breast Neoplasms
Caspase 9 promoter polymorphisms confer increased susceptibility to breast cancer.
Breast Neoplasms
Celastrol, a triterpene, enhances TRAIL-induced apoptosis through the down-regulation of cell survival proteins and up-regulation of death receptors.
Breast Neoplasms
Cell death induced by taxanes in breast cancer cells: cytochrome C is released in resistant but not in sensitive cells.
Breast Neoplasms
Chemotherapy with hybrid liposomes for human breast tumors along with apoptosis in vivo.
Breast Neoplasms
Cytotoxic activity of octahydropyrazin[2,1-a:5,4-a']diisoquinoline derivatives in human breast cancer cells.
Breast Neoplasms
d-3-Deoxy-dioctanoylphosphatidylinositol induces cytotoxicity in human MCF-7 breast cancer cells via a mechanism that involves downregulation of the D-type cyclin-retinoblastoma pathway.
Breast Neoplasms
Debio-0932, a second generation oral Hsp90 inhibitor, induces apoptosis in MCF-7 and MDA-MB-231 cell lines.
Breast Neoplasms
Design and synthesis of novel azapeptide activators of apoptosis mediated by caspase-9 in cancer cells.
Breast Neoplasms
DIRECT INDUCTION OF APOPTOSIS USING AN OPTIMAL MITOCHONDRIALLY TARGETED P53.
Breast Neoplasms
Dissection of signaling pathways in fourteen breast cancer cell lines using reverse-phase protein lysate microarray.
Breast Neoplasms
Ectopic expression of cyclin D1 amplifies a retinoic acid-induced mitochondrial death pathway in breast cancer cells.
Breast Neoplasms
Effects of geranyl-phloroacetophenone on the induction of apoptosis and chemosensitization of adriamycin-resistant MCF-7 human breast cancer cells.
Breast Neoplasms
Embryonic morphogen nodal promotes breast cancer growth and progression.
Breast Neoplasms
Emetine regulates the alternative splicing of caspase 9 in tumor cells.
Breast Neoplasms
EMP1, a member of a new family of antiproliferative genes in breast carcinoma.
Breast Neoplasms
Enhancement of tumor necrosis factor-alpha-induced growth inhibition by insulin-like growth factor-binding protein-5 (IGFBP-5), but not IGFBP-3 in human breast cancer cells.
Breast Neoplasms
Enterocarpam-III induces human liver and breast cancer cell apoptosis via mitochondrial and caspase-9 activation.
Breast Neoplasms
Equol induces apoptosis through cytochrome c-mediated caspases cascade in human breast cancer MDA-MB-453 cells.
Breast Neoplasms
Ethyl acetate extract of Patrinia scabiosaefolia downregulates anti-apoptotic Bcl-2/Bcl-X(L) expression, and induces apoptosis in human breast carcinoma MCF-7 cells independent of caspase-9 activation.
Breast Neoplasms
Expression and prognostic significance of osteopontin and caspase-3 in hepatocellular carcinoma patients after curative resection.
Breast Neoplasms
Fabrication of methotrexate-loaded gold nanoconjugates and its enhanced anticancer activity in breast cancer.
Breast Neoplasms
Ganoderma lucidum spore oil induces apoptosis of breast cancer cells in vitro and in vivo by activating caspase-3 and caspase-9.
Breast Neoplasms
Halilectin-3, a lectin from the marine sponge Haliclona caerulea, induces apoptosis and autophagy in human breast cancer MCF7 cells through caspase-9 pathway and LC3-II protein expression
Breast Neoplasms
ICE-LAP6, a novel member of the ICE/Ced-3 gene family, is activated by the cytotoxic T cell protease granzyme B.
Breast Neoplasms
Induction of Apoptosis and Autophagy by Ternary Copper Complex Towards Breast Cancer Cells.
Breast Neoplasms
Inflammation and IGF-I activate the Akt pathway in breast cancer.
Breast Neoplasms
Inhibitory effects of combination of lycopene and genistein on 7,12- dimethyl benz(a)anthracene-induced breast cancer in rats.
Breast Neoplasms
Involvement of caspase-9 but not caspase-8 in the anti-apoptotic effects of estradiol and 4-OH-Estradiol in MCF-7 human breast cancer cells.
Breast Neoplasms
LncRNA POU3F3 promotes proliferation and inhibits apoptosis of cancer cells in triple-negative breast cancer by inactivating caspase 9.
Breast Neoplasms
Myricetin Apoptotic Effects on T47D Breast Cancer Cells is a P53-Independent Approach.
Breast Neoplasms
Myricetin Exerts its Apoptotic Effects on MCF-7 Breast Cancer Cells through Evoking the BRCA1-GADD45 Pathway.
Breast Neoplasms
Nonpeptidic and potent small-molecule inhibitors of cIAP-1/2 and XIAP proteins.
Breast Neoplasms
Oxaliplatin-chitosan nanoparticles induced intrinsic apoptotic signaling pathway: A "smart" drug delivery system to breast cancer cell therapy.
Breast Neoplasms
Oxymatrine Promotes S-Phase Arrest and Inhibits Cell Proliferation of Human Breast Cancer Cells in Vitro through Mitochondria-Mediated Apoptosis.
Breast Neoplasms
Possible role of p53/Mieap-regulated mitochondrial quality control as a tumor suppressor in human breast cancer.
Breast Neoplasms
PQ1, a quinoline derivative, induces apoptosis in T47D breast cancer cells through activation of caspase-8 and caspase-9.
Breast Neoplasms
Puerariae radix isoflavones and their metabolites inhibit growth and induce apoptosis in breast cancer cells.
Breast Neoplasms
Rapid Upregulation of Cytoprotective Nitric Oxide in Breast Tumor Cells Subjected to a Photodynamic Therapy-like Oxidative Challenge.
Breast Neoplasms
Resveratrol-induced cell inhibition of growth and apoptosis in MCF7 human breast cancer cells are associated with modulation of phosphorylated Akt and caspase-9.
Breast Neoplasms
Role of caspase-8 activation in mediating vitamin E-induced apoptosis in murine mammary cancer cells.
Breast Neoplasms
Role of Endothelin 1 on Proliferation and Migration of Human MCF-7 Cells.
Breast Neoplasms
Roles of the Bcl-2/Bax ratio, caspase-8 and 9 in resistance of breast cancer cells to paclitaxel.
Breast Neoplasms
RRR-alpha-tocopheryl succinate-induced apoptosis of human breast cancer cells involves Bax translocation to mitochondria.
Breast Neoplasms
Ruanjian Sanjie decoction exhibits antitumor activity by inducing cell apoptosis in breast cancer.
Breast Neoplasms
Smac-mimetic compound SM-164 induces radiosensitization in breast cancer cells through activation of caspases and induction of apoptosis.
Breast Neoplasms
Solamargine induces apoptosis and sensitizes breast cancer cells to cisplatin.
Breast Neoplasms
Sulforaphane induces cell type-specific apoptosis in human breast cancer cell lines.
Breast Neoplasms
Super Magnetic Niosomal Nanocarrier as a New Approach for Treatment of Breast Cancer: A Case Study on SK-BR-3 and MDA-MB-231 Cell Lines.
Breast Neoplasms
Suppressing glucose metabolism with epigallocatechin-3-gallate (EGCG) reduces breast cancer cell growth in preclinical models.
Breast Neoplasms
Synthesis of a novel fluorescent berberine derivative convenient for its subcellular localization study.
Breast Neoplasms
Tamoxifen and TRAIL synergistically induce apoptosis in breast cancer cells.
Breast Neoplasms
Targeted inhibition of Notch1 gene enhances the killing effects of paclitaxel on triple negative breast cancer cells.
Breast Neoplasms
Taxol-induced apoptosis in human SKOV3 ovarian and MCF7 breast carcinoma cells is caspase-3 and caspase-9 independent.
Breast Neoplasms
The anticancer effect and mechanism of ?-hederin on breast cancer cells.
Breast Neoplasms
The differential sensitivity of Bc1-2-overexpressing human breast tumor cells to TRAIL or doxorubicin-induced apoptosis is dependent on Bc1-2 protein levels.
Breast Neoplasms
The mechanisms of lipoxygenase inhibitor-induced apoptosis in human breast cancer cells.
Breast Neoplasms
Transcript expression and genetic variability analysis of caspases in breast carcinomas suggests CASP9 as the most interesting target.
Breast Neoplasms
Treatment of MCF-7 cells with taxol and etoposide induces distinct alterations in the expression of apoptosis-related genes BCL2, BCL2L12, BAX, CASPASE-9 and FAS.
Breast Neoplasms
Tumor-suppressive effect of adenovirus-mediated inhibitor of growth 4 gene transfer in breast carcinoma cells in vitro and in vivo.
Breast Neoplasms
Typhonium flagelliforme extract induce apoptosis in breast cancer stem cells by suppressing survivin.
Breast Neoplasms
[Apoptosis resistance induced by leptin and its mechanism in breast cancer cells]
Breast Neoplasms
[Clinical and Functional Importance of Selected CASP8 and CASP9 Polymorphisms in Breast Carcinoma].
Breast Neoplasms
[Hirsutine induces apoptosis of human breast cancer MDA-MB-231 cells through mitochondrial pathway].
Carcinogenesis
Association of CASP9, CASP10 gene polymorphisms and tea drinking with colorectal cancer risk in the Han Chinese population.
Carcinogenesis
Beclin 1-mediated macroautophagy involves regulation of caspase-9 expression in cervical cancer HeLa cells.
Carcinogenesis
Caspase inhibition blocks cell death and enhances mitophagy but fails to promote T-cell lymphoma.
Carcinogenesis
Chemopreventive activity of Azadirachta indica on two-stage skin carcinogenesis in murine model.
Carcinogenesis
Chemopreventive activity of Hydroethanolic Murraya koenigii leaves extract (HEMKLE) against chemically induced skin carcinogenesis in mice.
Carcinogenesis
Chemopreventive efficacy of hesperidin against chemically induced nephrotoxicity and renal carcinogenesis via amelioration of oxidative stress and modulation of multiple molecular pathways.
Carcinogenesis
Effects of treatment of rats with indole-3-carbinol on apoptosis in the mammary gland and mammary adenocarcinomas.
Carcinogenesis
Genetic models of apoptosis-induced proliferation decipher activation of JNK and identify a requirement of EGFR signaling for tissue regenerative responses in Drosophila.
Carcinogenesis
Living or dying by RNA processing: caspase expression in NSCLC.
Carcinogenesis
Magnetite (Fe(3)O(4)) nanocrystals affect the expression of genes involved in the TGF-beta signalling pathway.
Carcinogenesis
MicroRNA-224 Promotes Tumorigenesis through Downregulation of Caspase-9 in Triple-Negative Breast Cancer.
Carcinogenesis
The potential tumour suppressor role for caspase-9 (CASP9) in the childhood malignancy, neuroblastoma.
Carcinogenesis
[A study on the expression of CASP9 gene and its polymorphism distribution in non-small cell lung cancer]
Carcinoma
125I seeds irradiation inhibits tumor growth and induces apoptosis by Ki-67, P21, survivin, livin and caspase-9 expression in lung carcinoma xenografts.
Carcinoma
?-Apo-13-carotenone regulates retinoid X receptor transcriptional activity through tetramerization of the receptor.
Carcinoma
A novel mechanism of CD40-induced apoptosis of carcinoma cells involving TRAF3 and JNK/AP-1 activation.
Carcinoma
Antiproliferative and Apoptotic Effects of Shemamruthaa, a Herbal Preparation, in 7,12-Dimethylbenz(a)Anthracene-Induced Breast Cancer Rats.
Carcinoma
Apoptosis induction in renal cell carcinoma by TRAIL and gamma-radiation is impaired by deficient caspase-9 cleavage.
Carcinoma
Atiprimod is an inhibitor of cancer cell proliferation and angiogenesis.
Carcinoma
Bovine lactoferricin selectively induces apoptosis in human leukemia and carcinoma cell lines.
Carcinoma
Cancer gene therapy with iCaspase-9 transcriptionally targeted to tumor endothelial cells.
Carcinoma
CASP9 c.-1339A>G and CASP3 c.-1191A>G polymorphisms alter susceptibility and clinical aspects of head and neck squamous cell carcinoma.
Carcinoma
Caspase-9 regulates cisplatin-induced apoptosis in human head and neck squamous cell carcinoma cells.
Carcinoma
CIAPIN1 and ABCA13 are markers of poor survival in metastatic ovarian serous carcinoma.
Carcinoma
Comparative evaluation of antiproliferative, antiangiogenic and apoptosis inducing potential of black tea polyphenols in the hamster buccal pouch carcinogenesis model.
Carcinoma
Crosstalk between p38 MAPK and caspase-9 regulates mitochondria-mediated apoptosis induced by tetra-?-(4-carboxyphenoxy) phthalocyanine zinc photodynamic therapy in LoVo cells.
Carcinoma
CXCL12 chemokine expression and secretion regulates colorectal carcinoma cell anoikis through bim-mediated intrinsic apoptosis.
Carcinoma
Dasatinib reduces 5-Fu-triggered apoptosis in colon carcinoma by directly modulating Src-dependent caspase-9 phosphorylation.
Carcinoma
Defining characteristics of Types I and II apoptotic cells in response to TRAIL.
Carcinoma
Degradation of Sargassum crassifolium Fucoidan by Ascorbic Acid and Hydrogen Peroxide, and Compositional, Structural, and In Vitro Anti-Lung Cancer Analyses of the Degradation Products.
Carcinoma
Exogenous morphine inhibits human gastric cancer MGC- 803 cell growth by cell cycle arrest and apoptosis induction.
Carcinoma
Expression and prognostic significance of APAF-1, caspase-8 and caspase-9 in stage II/III colon carcinoma: Caspase-8 and caspase-9 is associated with poor prognosis.
Carcinoma
Expression and Prognostic Significance of Livin, Caspase-3, and Ki-67 in the Progression of Human Ampullary Carcinoma.
Carcinoma
Expression of apoptosis-related proteins caspase-6, caspase-9, FLIP and BNIP3 in oesophageal squamous cell carcinomas.
Carcinoma
Expression of phosphorylated caspase-9 in gastric carcinomas.
Carcinoma
Fas/FasL of pacific cod mediated apoptosis.
Carcinoma
Glucocorticoid cotreatment induces apoptosis resistance toward cancer therapy in carcinomas.
Carcinoma
Icariin reduces human colon carcinoma cell growth and metastasis by enhancing p53 activities.
Carcinoma
Immune clearance gastric carcinoma cells in ascites by activating caspase-9-induced apoptosis.
Carcinoma
In vivo photoacoustic imaging of chemotherapy-induced apoptosis in squamous cell carcinoma using a near-infrared caspase-9 probe.
Carcinoma
Influence of CASP9 c.-1339A>G and CASP3 c.-1191A>G variants in outcome of patients with head and neck squamous cell carcinoma.
Carcinoma
Influence of survivin (BIRC5) and caspase-9 (CASP9) functional polymorphisms in renal cell carcinoma development: a study in a southern European population.
Carcinoma
Influence of Tanshinone IIA on apoptosis of human esophageal carcinoma Eca-109 cells and its molecular mechanism.
Carcinoma
Inhibition of caspase-9 activity and Apaf-1 expression in cisplatin-resistant head and neck squamous cell carcinoma cells.
Carcinoma
Inhibition of tumour cell growth by hyperforin, a novel anticancer drug from St. John's wort that acts by induction of apoptosis.
Carcinoma
Inhibitors of MEK1/2 interact with UCN-01 to induce apoptosis and reduce colony formation in mammary and prostate carcinoma cells.
Carcinoma
Melatonin influences pancreatic cancerogenesis.
Carcinoma
Modulating effect of hesperetin on the molecular expression pattern of apoptotic and cell proliferative markers in 7,12-dimethylbenz(a)anthracene-induced oral carcinogenesis.
Carcinoma
Mutational analysis of proapoptotic caspase-9 gene in common human carcinomas.
Carcinoma
p21 blocks irradiation-induced apoptosis downstream of mitochondria by inhibition of cyclin-dependent kinase-mediated caspase-9 activation.
Carcinoma
Physcion from marine-derived fungus Microsporum sp. induces apoptosis in human cervical carcinoma HeLa cells.
Carcinoma
Phytol induces ROS mediated apoptosis by induction of caspase 9 and 3 through activation of TRAIL, FAS and TNF receptors and inhibits tumor progression factor Glucose 6 phosphate dehydrogenase in lung carcinoma cell line (A549).
Carcinoma
Potential role of Notch1 signaling pathway in laryngeal squamous cell carcinoma cell line Hep-2 involving proliferation inhibition, cell cycle arrest, cell apoptosis, and cell migration.
Carcinoma
Protein expression differences between lung adenocarcinoma and squamous cell carcinoma with brain metastasis.
Carcinoma
Sam68 reduces cisplatin-induced apoptosis in tongue carcinoma.
Carcinoma
Smac/DIABLO expression in human gastrointestinal carcinoma: Association with clinicopathological parameters and survivin expression.
Carcinoma
The anti-tumour activity of rLj-RGD4, an RGD toxin protein from Lampetra japonica, on human laryngeal squamous carcinoma Hep-2 cells in nude mice.
Carcinoma
The association of taxane resistance genes with the clinical course of ovarian carcinoma.
Carcinoma
The E3 ligase HECTD3 promotes esophageal squamous cell carcinoma (ESCC) growth and cell survival through targeting and inhibiting caspase-9 activation.
Carcinoma
Triptolide induces s phase arrest and apoptosis in gallbladder cancer cells.
Carcinoma
Up-regulation of FLIP in cisplatin-selected HeLa cells causes cross-resistance to CD95/Fas death signalling.
Carcinoma
[Effects of salinomycin on proliferation and apoptosis of oral squamous cell carcinoma].
Carcinoma
[Inhibition of caspase-9 activity in cisplatin-resistant head and neck squamous cell carcinoma]
Carcinoma
[Study on the effects of mitochondrial pathways on apoptosis in colon carcinoma cells induced by tumor necrosis factor related apoptosis inducing ligand]
Carcinoma, Embryonal
Akt phosphorylation site found in human caspase-9 is absent in mouse caspase-9.
Carcinoma, Embryonal
BMP-4 and retinoic acid synergistically induce activation of caspase-9 and cause apoptosis of P19 embryonal carcinoma cells cultured as a monolayer.
Carcinoma, Embryonal
ER stress induces caspase-8 activation, stimulating cytochrome c release and caspase-9 activation.
Carcinoma, Embryonal
RC-6 ribonuclease induces caspase activation, cellular senescence and neuron-like morphology in NT2 embryonal carcinoma cells.
Carcinoma, Hepatocellular
Baicalin and the liver-gut system: Pharmacological bases explaining its therapeutic effects.
Carcinoma, Hepatocellular
Cancer gene therapy with iCaspase-9 transcriptionally targeted to tumor endothelial cells.
Carcinoma, Hepatocellular
Combination Suicide Gene Delivery with an Adeno-Associated Virus Vector Encoding Inducible Caspase-9 and a Chemical Inducer of Dimerization Is Effective in a Xenotransplantation Model of Hepatocellular Carcinoma.
Carcinoma, Hepatocellular
FTY720 induces apoptosis of human hepatoma cell lines through PI3-K-mediated Akt dephosphorylation.
Carcinoma, Hepatocellular
In vitro and in vivo effects and mechanisms of celecoxib-induced growth inhibition of human hepatocellular carcinoma cells.
Carcinoma, Hepatocellular
Isolation of 4,4'-bond secalonic acid D from the marine-derived fungus Penicillium oxalicum with inhibitory property against hepatocellular carcinoma.
Carcinoma, Hepatocellular
LINC01980 stimulates the progression of hepatocellular carcinoma via downregulating caspase 9.
Carcinoma, Hepatocellular
Mitochondria-mediated tumstatin peptide-induced HepG2 cell apoptosis.
Carcinoma, Hepatocellular
Oncogenic miR-96-5p inhibits apoptosis by targeting the caspase-9 gene in hepatocellular carcinoma.
Carcinoma, Hepatocellular
Potentiation of the antitumor effects of both selective cyclooxygenase-1 and cyclooxygenase-2 inhibitors in human hepatic cancer cells by inhibition of the MEK/ERK pathway.
Carcinoma, Hepatocellular
Solamargine triggers hepatoma cell death through apoptosis.
Carcinoma, Hepatocellular
Synergistic Antitumor Effect of 5-Fluorouracil Combined with Constituents from Pleurospermum lindleyanum in Hepatocellular carcinoma SMMC-7721 Cells.
Carcinoma, Hepatocellular
Translocase of outer mitochondrial membrane 70 expression is induced by hepatitis C virus and is related to the apoptotic response.
Carcinoma, Non-Small-Cell Lung
?-Hydroxyundec-9-enoic acid induces apoptosis through ROS-mediated endoplasmic reticulum stress in non-small cell lung cancer cells.
Carcinoma, Non-Small-Cell Lung
hnRNP L regulates the tumorigenic capacity of lung cancer xenografts in mice via caspase-9 pre-mRNA processing.
Carcinoma, Non-Small-Cell Lung
Investigation of Caspase 9 Gene Polymorphism in Patients With Non-small Cell Lung Cancer.
Carcinoma, Non-Small-Cell Lung
Prodrug-Like, PEGylated Protein Toxin Trichosanthin for Reversal of Chemoresistance.
Carcinoma, Non-Small-Cell Lung
Prognostic assessment of apoptotic gene polymorphisms in non-small cell lung cancer in Chinese.
Carcinoma, Non-Small-Cell Lung
RNAi targeting STMN alleviates the resistance to taxol and collectively contributes to down regulate the malignancy of NSCLC cells in vitro and in vivo.
Carcinoma, Non-Small-Cell Lung
Role of XIAP in inhibiting cisplatin-induced caspase activation in non-small cell lung cancer cells: a small molecule Smac mimic sensitizes for chemotherapy-induced apoptosis by enhancing caspase-3 activation.
Carcinoma, Non-Small-Cell Lung
SRSF1 Regulates the Alternative Splicing of Caspase 9 Via A Novel Intronic Splicing Enhancer Affecting the Chemotherapeutic Sensitivity of Non-Small Cell Lung Cancer Cells.
Carcinoma, Non-Small-Cell Lung
Sulindac enhances adenoviral vector expressing mda-7/IL-24-mediated apoptosis in human lung cancer.
Carcinoma, Non-Small-Cell Lung
The caspase 9 inhibitor Z-LEHD-FMK protects human liver cells while permitting death of cancer cells exposed to tumor necrosis factor-related apoptosis-inducing ligand.
Carcinoma, Non-Small-Cell Lung
[A study on the expression of CASP9 gene and its polymorphism distribution in non-small cell lung cancer]
Carcinoma, Renal Cell
Apoptosis induction in renal cell carcinoma by TRAIL and gamma-radiation is impaired by deficient caspase-9 cleavage.
Carcinoma, Renal Cell
Influence of survivin (BIRC5) and caspase-9 (CASP9) functional polymorphisms in renal cell carcinoma development: a study in a southern European population.
Carcinoma, Squamous Cell
Anticancer effects induced by artichoke extract in oral squamous carcinoma cell lines.
Carcinoma, Squamous Cell
Cancer gene therapy with iCaspase-9 transcriptionally targeted to tumor endothelial cells.
Carcinoma, Squamous Cell
CASP9 c.-1339A>G and CASP3 c.-1191A>G polymorphisms alter susceptibility and clinical aspects of head and neck squamous cell carcinoma.
Carcinoma, Squamous Cell
Caspase-9 regulates cisplatin-induced apoptosis in human head and neck squamous cell carcinoma cells.
Carcinoma, Squamous Cell
Expression of apoptosis-related proteins caspase-6, caspase-9, FLIP and BNIP3 in oesophageal squamous cell carcinomas.
Carcinoma, Squamous Cell
In vivo photoacoustic imaging of chemotherapy-induced apoptosis in squamous cell carcinoma using a near-infrared caspase-9 probe.
Carcinoma, Squamous Cell
Influence of CASP9 c.-1339A>G and CASP3 c.-1191A>G variants in outcome of patients with head and neck squamous cell carcinoma.
Carcinoma, Squamous Cell
Inhibition of caspase-9 activity and Apaf-1 expression in cisplatin-resistant head and neck squamous cell carcinoma cells.
Carcinoma, Squamous Cell
Modulating effect of hesperetin on the molecular expression pattern of apoptotic and cell proliferative markers in 7,12-dimethylbenz(a)anthracene-induced oral carcinogenesis.
Carcinoma, Squamous Cell
Protein expression differences between lung adenocarcinoma and squamous cell carcinoma with brain metastasis.
Carcinoma, Squamous Cell
Sam68 reduces cisplatin-induced apoptosis in tongue carcinoma.
Carcinoma, Squamous Cell
[Inhibition of caspase-9 activity in cisplatin-resistant head and neck squamous cell carcinoma]
Cardiomegaly
Fatty acid-binding protein 4 silencing protects against lipopolysaccharide-induced cardiomyocyte hypertrophy and apoptosis by inhibiting the Toll-like receptor 4-nuclear factor-?B pathway.
Cardiomegaly
Intramyocardial VEGF-B167 Gene Delivery Delays the Progression Towards Congestive Failure in Dogs With Pacing-Induced Dilated Cardiomyopathy.
Cardiomyopathies
Caspase-9: A Multimodal Therapeutic Target With Diverse Cellular Expression in Human Disease.
Cardiotoxicity
?-asarone induces cardiac defects and QT prolongation through mitochondrial apoptosis pathway in zebrafish.
caspase-6 deficiency
Caspase regulation of genotoxin-induced neural precursor cell death.
caspase-8 deficiency
ER stress induces caspase-8 activation, stimulating cytochrome c release and caspase-9 activation.
caspase-9 deficiency
Apaf-1 and caspase-9 deficiency prevents apoptosis in a Bax-controlled pathway and promotes clonogenic survival during paclitaxel treatment.
caspase-9 deficiency
Bcl-X(L)-caspase-9 interactions in the developing nervous system: evidence for multiple death pathways.
caspase-9 deficiency
Caspase inhibition extends the commitment to neuronal death beyond cytochrome c release to the point of mitochondrial depolarization.
caspase-9 deficiency
Caspase-9 acts as a regulator of necroptotic cell death.
caspase-9 deficiency
Caspase-9 is required for normal hematopoietic development and protection from alkylator-induced DNA damage in mice.
caspase-9 deficiency
Interplay between Caspase 9 and X-linked Inhibitor of Apoptosis Protein (XIAP) in the oocyte elimination during fetal mouse development.
caspase-9 deficiency
Lidocaine induces apoptosis via the mitochondrial pathway independently of death receptor signaling.
caspase-9 deficiency
The autoimmune conundrum in common variable immunodeficiency disorders.
Cataract
Effects of ELL-associated factor 2 on ultraviolet radiation-induced cataract formation in mice.
Cataract
Parthenolide protects human lens epithelial cells from oxidative stress-induced apoptosis via inhibition of activation of caspase-3 and caspase-9.
Cataract
Role of the intrinsic apoptotic pathway in cataractogenesis in type 2 diabetic patients.
Cell Transformation, Neoplastic
Fail-Safe System against Potential Tumorigenicity after Transplantation of iPSC Derivatives.
Cerebral Hemorrhage
[Effect of manual acupuncture of "Shuigou" (GV26)"Neiguan" (PC6) on neurological function and expression of apoptosis-related factors in brain tissues surrounding hematoma in intracerebral hemorrhage rats].
Chlamydophila Infections
An epistatic effect of apaf-1 and caspase-9 on chlamydial infection.
Cholangiocarcinoma
A Ligand for Peroxisome Proliferator-Activated Receptor gamma Inhibits Human Cholangiocarcinoma Cell Growth: Potential Molecular Targeting Strategy for Cholangioma.
Cholangiocarcinoma
Effect of (103)Pd radioactive stent on caspase-9, cholangiocarcinoma cell growth and its radiosensitivity.
Cholestasis, Intrahepatic
Fas, Caspase-8, and Caspase-9 pathway-mediated bile acid-induced fetal cardiomyocyte apoptosis in intrahepatic cholestasis pregnant rat models.
Chondrosarcoma
BL-038, a Benzofuran Derivative, Induces Cell Apoptosis in Human Chondrosarcoma Cells through Reactive Oxygen Species/Mitochondrial Dysfunction and the Caspases Dependent Pathway.
Chondrosarcoma
FPTB, a novel CA-4 derivative, induces cell apoptosis of human chondrosarcoma cells through mitochondrial dysfunction and endoplasmic reticulum stress pathways.
Chondrosarcoma
Recombinant human PDCD5 sensitizes chondrosarcomas to cisplatin chemotherapy in vitro and in vivo.
Chordoma
Mapping of candidate region for chordoma development to 1p36.13 by LOH analysis.
Choriocarcinoma
Long Noncoding RNA LINC00261 Suppresses Cell Proliferation and Invasion and Promotes Cell Apoptosis in Human Choriocarcinoma.
Choriocarcinoma
Methotrexate induces apoptosis of human choriocarcinoma cell line JAR via a mitochondrial pathway.
Chronic Periodontitis
Porphyromonas gingivalis Differentially Modulates Apoptosome Apoptotic Peptidase Activating Factor 1 in Epithelial Cells and Fibroblasts.
Clubfoot
Apoptotic gene analysis in idiopathic talipes equinovarus (clubfoot).
Colitis
Extracellular Vesicles Derived from Bone Marrow Mesenchymal Stem Cells Protect against Experimental Colitis via Attenuating Colon Inflammation, Oxidative Stress and Apoptosis.
Colitis
Neutrophil apoptosis is delayed in an equine model of colitis: Implications for the development of SIRS.
Colitis, Ulcerative
Imbalance of Controlled Death in Peripheral Blood Lymphocytes in Crohn's Disease and Ulcerative Colitis.
Colonic Neoplasms
A ginger derivative, zingerone-a phenolic compound-induces ROS-mediated apoptosis in colon cancer cells (HCT-116).
Colonic Neoplasms
An active molecule from Pulsatilla chinensis, Pulsatilla saponin A, induces apoptosis and inhibits tumor growth of human colon cancer cells without or with 5-FU.
Colonic Neoplasms
Apoptotic block in colon cancer cells may be rectified by lentivirus mediated overexpression of caspase-9.
Colonic Neoplasms
Apoptotic Effect of Saccharomyces cerevisiae on Human Colon Cancer SW480 Cells by Regulation of Akt/NF-?B Signaling Pathway.
Colonic Neoplasms
Attacking the mitochondria of colorectal carcinoma by novel 2-cyanoacrylamides linked to ethyl 1,3-diphenylpyrazole-4-carboxylates moiety as a new trend for chemotherapy.
Colonic Neoplasms
Augmentation of sodium butyrate-induced apoptosis by phosphatidylinositol 3'-kinase inhibition in the KM20 human colon cancer cell line.
Colonic Neoplasms
Bik/NBK accumulation correlates with apoptosis-induction by bortezomib (PS-341, Velcade) and other proteasome inhibitors.
Colonic Neoplasms
Cardamonin Sensitizes Tumor Cells to TRAIL Through ROS- and CHOP-Mediated Upregulation of Death Receptors and Downregulation of Survival Proteins.
Colonic Neoplasms
Caspase 7 downregulation as an immunohistochemical marker of colonic carcinoma.
Colonic Neoplasms
Chitosan-coated Zn-metal-organic framework nanocomposites for effective targeted delivery of LNA-antisense miR-224 to colon tumor: in vitro studies.
Colonic Neoplasms
Cytotoxic effects of Echinacea purpurea flower extracts and cichoric acid on human colon cancer cells through induction of apoptosis.
Colonic Neoplasms
Defining characteristics of Types I and II apoptotic cells in response to TRAIL.
Colonic Neoplasms
HUHS1015 Suppresses Colonic Cancer Growth by Inducing Necrosis and Apoptosis in Association with Mitochondrial Damage.
Colonic Neoplasms
Inducing apoptosis of human colon cancer cells by an IGF-I D domain analogue peptide.
Colonic Neoplasms
Induction of apoptosis in colon cancer cells by cyclooxygenase-2 inhibitor NS398 through a cytochrome c-dependent pathway.
Colonic Neoplasms
Methyl Sartortuoate Inhibits Colon Cancer Cell Growth by Inducing Apoptosis and G2/M-Phase Arrest.
Colonic Neoplasms
Photodynamic therapy with the phthalocyanine photosensitizer Pc 4 of SW480 human colon cancer xenografts in athymic mice.
Colonic Neoplasms
Pinocembrin triggers Bax-dependent mitochondrial apoptosis in colon cancer cells.
Colonic Neoplasms
Regulation of caspase expression and apoptosis by adenomatous polyposis coli.
Colonic Neoplasms
The ?6-integrin-ERK/MAP kinase pathway contributes to chemo resistance in colon cancer.
Colonic Neoplasms
The caspase 9 inhibitor Z-LEHD-FMK protects human liver cells while permitting death of cancer cells exposed to tumor necrosis factor-related apoptosis-inducing ligand.
Colonic Neoplasms
The monoclonal antibody 225 activates caspase-8 and induces apoptosis through a tumor necrosis factor receptor family-independent pathway.
Colonic Neoplasms
Unconjugated bilirubin induces apoptosis in colon cancer cells by triggering mitochondrial depolarization.
Colonic Neoplasms
Vitexin-2-O-xyloside, raphasatin and (-)-epigallocatechin-3-gallate synergistically affect cell growth and apoptosis of colon cancer cells.
Colonic Neoplasms
[Down-regulation of sphingosine kinase 1 (SphK1) enhances the chemosensitivity to cisplatin in human colon cancer RKO cells].
Colorectal Neoplasms
Antibody against N-terminal domain of phospholipid scramblase 1 induces apoptosis in colorectal cancer cells through the intrinsic apoptotic pathway.
Colorectal Neoplasms
Apoptotic block in colon cancer cells may be rectified by lentivirus mediated overexpression of caspase-9.
Colorectal Neoplasms
Association of CASP9, CASP10 gene polymorphisms and tea drinking with colorectal cancer risk in the Han Chinese population.
Colorectal Neoplasms
Attacking the mitochondria of colorectal carcinoma by novel 2-cyanoacrylamides linked to ethyl 1,3-diphenylpyrazole-4-carboxylates moiety as a new trend for chemotherapy.
Colorectal Neoplasms
Baicalin and the liver-gut system: Pharmacological bases explaining its therapeutic effects.
Colorectal Neoplasms
Diallyl trisulfide induces apoptosis in human primary colorectal cancer cells.
Colorectal Neoplasms
Down regulation of caspase-9 is a frequent event in patients with stage II colorectal cancer and correlates with poor clinical outcome.
Colorectal Neoplasms
Erastin Disrupts Mitochondrial Permeability Transition Pore (mPTP) and Induces Apoptotic Death of Colorectal Cancer Cells.
Colorectal Neoplasms
Knockdown of MiR-20a Enhances Sensitivity of Colorectal Cancer Cells to Cisplatin by Increasing ASK1 Expression.
Colorectal Neoplasms
Modulation of gene expression in CD4+ T lymphocytes following in vitro HIV infection: a comparison between human and chimpanzee.
Colorectal Neoplasms
Molecular docking data of piperine with Bax, Caspase 3, Cox 2 and Caspase 9.
Colorectal Neoplasms
Phosphorylation status of Akt and caspase-9 in gastric and colorectal carcinomas.
Colorectal Neoplasms
Polymorphisms of Caspase 8 and Caspase 9 gene and colorectal cancer susceptibility and prognosis.
Colorectal Neoplasms
Requirement of BAX for TRAIL/Apo2L-induced apoptosis of colorectal cancers: synergism with sulindac-mediated inhibition of Bcl-x(L).
Colorectal Neoplasms
Smac/DIABLO expression in human gastrointestinal carcinoma: Association with clinicopathological parameters and survivin expression.
Colorectal Neoplasms
Targeting colorectal cancer stem cells with inducible caspase-9.
Congenital Abnormalities
Calcium Alleviates Fluoride-Induced Bone Damage by Inhibiting Endoplasmic Reticulum Stress and Mitochondrial Dysfunction.
Congenital Abnormalities
Gamma-irradiation-induced testicular oxidative stress and apoptosis: Mitigation by l-carnitine.
Coronary Disease
[Effect of Gualou Xiebai Banxia decoction combined with Xuefu Zhuyu decoction on myocardial apoptosis and relevant protein expressions in miniature swine phlegm and blood stasis type coronary heart disease model].
Coronavirus Infections
Equine coronavirus induces apoptosis in cultured cells.
Coronavirus Infections
Porcine hemagglutinating encephalomyelitis virus induces apoptosis in a porcine kidney cell line via caspase-dependent pathways.
COVID-19
COVID-19 and male reproductive function: a prospective, longitudinal cohort study.
Crohn Disease
Imbalance of Controlled Death in Peripheral Blood Lymphocytes in Crohn's Disease and Ulcerative Colitis.
Crohn Disease
Polymorphisms in apoptosis genes predict response to infliximab therapy in luminal and fistulizing Crohn's disease.
Cystadenocarcinoma, Serous
A Network Pharmacology-Based Analysis of Multi-Target, Multi-Pathway, Multi-Compound Treatment for Ovarian Serous Cystadenocarcinoma.
Cysts
Chronic effects of maternal tobacco-smoke exposure and/or ?-lipoic acid treatment on reproductive parameters in female rat offspring.
Cysts
Effect of calcium hydroxide as intracanal medicament on the expression of caspase-9 located within the radicular cyst epithelium.
Dehydration
Effects of long-term dehydration on oxidative stress, apoptotic markers and neuropeptides in the gastric mucosa of the dromedary camel.
Dehydration
Immunohistochemical expression of Bcl-2, p53 and caspase-9 in hypothalamus magnocellular centers of nNOS knockout mice following water deprivation.
Dementia
Caspase-9 mediates synaptic plasticity and memory deficits of Danish dementia knock-in mice: caspase-9 inhibition provides therapeutic protection.
Diabetic Nephropathies
Immunohistochemical Aspects of Cell Death in Diabetic Nephropathy.
Diabetic Retinopathy
Mitochondria- and caspase-dependent cell death pathway involved in neuronal degeneration in diabetic retinopathy.
Diabetic Retinopathy
Role of the intrinsic apoptotic pathway in cataractogenesis in type 2 diabetic patients.
Dwarfism
The ras-GTPase activity of neurofibromin restrains ERK-dependent FGFR signaling during endochondral bone formation.
e2 ubiquitin-conjugating enzyme deficiency
UbcH10 overexpression increases carcinogenesis and blocks ALLN susceptibility in colorectal cancer.
Encephalitis, Japanese
Rana catesbeiana ribonuclease inhibits Japanese encephalitis virus (JEV) replication and enhances apoptosis of JEV-infected BHK-21 cells.
Encephalocele
Apoptosis, Expression of PAX3 and P53, and Caspase Signal in Fetuses with Neural Tube Defects.
Endometrial Hyperplasia
Autophagy in the physiological endometrium and cancer.
Endometrial Neoplasms
Autophagy in the physiological endometrium and cancer.
Endometrial Neoplasms
Effects of 1alpha, 25-dihydroxyvitamin D3 on programmed cell death of Ishikawa endometrial cancer cells through ezrin phosphorylation.
Endometrial Neoplasms
Effects of Novel Alkyl Pyridine Platinum Complexes on Apoptosis in Ishikawa Endometrial Cancer Cells.
Endometrial Neoplasms
Histone deacetylase inhibitors induce apoptosis in both Type I and Type II endometrial cancer cells.
Endometrial Neoplasms
MLH1 enhances the sensitivity of human endometrial carcinoma cells to cisplatin by activating the MLH1/c-Abl apoptosis signaling pathway.
Endometrial Neoplasms
Progesterone induces apoptosis by activation of caspase-8 and calcitriol via activation of caspase-9 pathways in ovarian and endometrial cancer cells in vitro.
Endometrial Neoplasms
The SGK1 inhibitor SI113 induces autophagy, apoptosis, and endoplasmic reticulum stress in endometrial cancer cells.
Endometriosis
Mullerian inhibiting substance suppresses proliferation and induces apoptosis and autophagy in endometriosis cells in vitro.
Endotoxemia
Long-lasting effect of infant rats endotoxemia on heat shock protein 60 in the pancreatic acinar cells: involvement of toll-like receptor 4.
Epilepsy
Bcl-2 and Caspase-9 serum levels in children and adolescents with idiopathic epilepsy and active seizures.
Epilepsy
Down-Regulation of Mir-145 Improves Learning and Memory Abilities in Epileptic Rats by Regulating Hippocampal Neuron Apoptosis.
Epistaxis
Caspase 3 activation in nasal capillary in patients with epistaxis.
Epstein-Barr Virus Infections
Proteomics Analysis of Gastric Epithelial AGS Cells Infected with Epstein-Barr Virus.
Escherichia coli Infections
Hepatic histopathology and apoptosis in diet-induced-obese mice under Escherichia coli pneumonia.
Esophageal Neoplasms
[Expressions and clinical significances of iASPP and caspase-9 in esophageal cancer].
Esophageal Neoplasms
[THAP11 mediates the proliferation and apoptosis of esophageal cancer cells via inhibiting ubiquitination of p53].
Esophageal Squamous Cell Carcinoma
The E3 ligase HECTD3 promotes esophageal squamous cell carcinoma (ESCC) growth and cell survival through targeting and inhibiting caspase-9 activation.
Fatty Liver
Cytoprotective Mechanisms in Fatty Liver Preservation against Cold Ischemia Injury: A Comparison between IGL-1 and HTK.
Fatty Liver
Huperzine A attenuates nonalcoholic fatty liver disease by regulating hepatocyte senescence and apoptosis: an in vitro study.
Fetal Growth Retardation
Serum Bcl-2, caspase-9 and soluble FasL levels as perinatal markers in late preterm pregnancies with intrauterine growth restriction.
Fibrosarcoma
Autocrine motility factor signaling induces tumor apoptotic resistance by regulations Apaf-1 and Caspase-9 apoptosome expression.
Fibrosarcoma
The antiproliferative function of violacein-like purple violet pigment (PVP) from an Antarctic Janthinobacterium sp. Ant5-2 in UV-induced 2237 fibrosarcoma.
Follicular Cyst
Chronic effects of maternal tobacco-smoke exposure and/or ?-lipoic acid treatment on reproductive parameters in female rat offspring.
Food Hypersensitivity
[Soluble apoptosis markers in obese patients with food intolerance].
Fuchs' Endothelial Dystrophy
Unfolded protein response in fuchs endothelial corneal dystrophy: a unifying pathogenic pathway?
Gallbladder Neoplasms
Triptolide induces s phase arrest and apoptosis in gallbladder cancer cells.
Gastritis
Dysregulated Expression of Apoptosis-Associated Genes and MicroRNAs and Their Involvement in Gastric Carcinogenesis.
Gastrointestinal Neoplasms
Phosphorylation status of Akt and caspase-9 in gastric and colorectal carcinomas.
Glaucoma
Activation of caspase 9 in a rat model of experimental glaucoma.
Glioblastoma
Activation of caspase-9 with irradiation inhibits invasion and angiogenesis in SNB19 human glioma cells.
Glioblastoma
Glioblastoma cell death induced by asiatic acid.
Glioblastoma
High expression of XIAP and Bcl-2 may inhibit programmed cell death in glioblastomas.
Glioblastoma
Immunocytochemical detection of members of the caspase cascade of apoptosis in high-grade astrocytomas.
Glioblastoma
Immunohistochemical localization of caspase-3, caspase-9 and Bax in U87 glioblastoma xenografts.
Glioblastoma
Investigation of U-251 cell death triggered by flavonoid luteolin: towards a better understanding on its anticancer property against glioblastomas.
Glioblastoma
Major Contribution of Caspase-9 to Honokiol-Induced Apoptotic Insults to Human Drug-Resistant Glioblastoma Cells.
Glioblastoma
MEG-3-mediated Wnt/?-catenin signaling pathway controls the inhibition of tunicamycin-mediated viability in glioblastoma.
Glioblastoma
N-(4-Hydroxyphenyl)retinamide induced differentiation with repression of telomerase and cell cycle to increase interferon-gamma sensitivity for apoptosis in human glioblastoma cells.
Glioblastoma
Novel anti-apoptotic microRNAs 582-5p and 363 promote human glioblastoma stem cell survival via direct inhibition of caspase 3, caspase 9, and Bim.
Glioblastoma
Protein kinase C-eta regulates resistance to UV- and gamma-irradiation-induced apoptosis in glioblastoma cells by preventing caspase-9 activation.
Glioblastoma
REIC/Dkk-3 induces cell death in human malignant glioma.
Glioblastoma
The growth of the canine glioblastoma cell line D-GBM and the canine histiocytic sarcoma cell line DH82 is inhibited by the resveratrol oligomers hopeaphenol and r2-viniferin.
Glioma
?-elemene induces glioma cell apoptosis by downregulating survivin and its interaction with hepatitis B X-interacting protein.
Glioma
Activation of caspase-9 with irradiation inhibits invasion and angiogenesis in SNB19 human glioma cells.
Glioma
Apoptosis induced by temozolomide and nimustine in glioblastoma cells is supported by JNK/c-Jun-mediated induction of the BH3-only protein BIM.
Glioma
Bax and Bid act in synergy to bring about T11TS-mediated glioma apoptosis via the release of mitochondrial cytochrome c and subsequent caspase activation.
Glioma
CASP9 Germline Mutation in a Family with Multiple Brain Tumors.
Glioma
Caspase-9 pathway activation by inhibiting endogenous fibroblast growth factor signaling in human glioma cells.
Glioma
Caspase-9 transduction overrides the resistance mechanism against p53-mediated apoptosis in U-87MG glioma cells.
Glioma
Caspase-9 transduction overrides the resistance mechanism against p53-mediated apoptosis in U87MG glioma cells.
Glioma
Co-transduction of Apaf-1 and caspase-9 augments etoposide-induced apoptosis in U-373MG glioma cells.
Glioma
Co-transduction of Apaf-1 and caspase-9 highly enhances p53-mediated apoptosis in gliomas.
Glioma
Combination of measles virus virotherapy and radiation therapy has synergistic activity in the treatment of glioblastoma multiforme.
Glioma
Conditioned media from human adipose tissue-derived mesenchymal stem cells and umbilical cord-derived mesenchymal stem cells efficiently induced the apoptosis and differentiation in human glioma cell lines in vitro.
Glioma
Cord blood stem cell-mediated induction of apoptosis in glioma downregulates X-linked inhibitor of apoptosis protein (XIAP).
Glioma
Delayed growth of glioma by a polysaccharide from Aster tataricus involve upregulation of Bax/Bcl-2 ratio, activation of caspase-3/8/9, and downregulation of the Akt.
Glioma
Desipramine induces apoptosis in rat glioma cells via endoplasmic reticulum stress-dependent CHOP pathway.
Glioma
Effects of microRNA-195 on the Prognosis of Glioma Patients and the Proliferation and Apoptosis of Human Glioma Cells.
Glioma
Evodiamine Prevents Glioma Growth, Induces Glioblastoma Cell Apoptosis and Cell Cycle Arrest through JNK Activation.
Glioma
Extracts of marine sponge Polymastia janeirensis induce oxidative cell death through a caspase-9 apoptotic pathway in human U138MG glioma cell line.
Glioma
Gene therapy using an adenovirus vector for apoptosis-related genes is a highly effective therapeutic modality for killing glioma cells.
Glioma
Human malignant glioma therapy using anti-alpha(v)beta3 integrin agents.
Glioma
Induction of apoptosis in mammalian cells by cadmium and zinc.
Glioma
Induction of apoptosis in resistant glioma cells by synthetic caspase-activation.
Glioma
Inhibition of ?-opioid receptors induces brain glioma cell apoptosis through the mitochondrial and protein kinase C pathways.
Glioma
Juglone induces apoptosis of tumor stem-like cells through ROS-p38 pathway in glioblastoma.
Glioma
Knockdown of ADAMDEC1 inhibits the progression of glioma in vitro.
Glioma
Mangiferin regulates proliferation and apoptosis in glioma cells by induction of microRNA-15b and inhibition of MMP-9 expression.
Glioma
Mechanism of As2O3 induces apoptosis of glioma U87 cells.
Glioma
MicroRNA-21 promotes glioma cell proliferation and inhibits senescence and apoptosis by targeting SPRY1 via the PTEN/PI3K/AKT signaling pathway.
Glioma
MiR-135a and MRP1 play pivotal roles in the selective lethality of phenethyl isothiocyanate to malignant glioma cells.
Glioma
Oroxyloside inhibits human glioma progression by suppressing proliferation, metastasis and inducing apoptosis related pathways.
Glioma
Over-expression of APAF-1 and caspase-9 augments radiation-induced apoptosis in U-373MG glioma cells.
Glioma
Reduction of miR-21 induces glioma cell apoptosis via activating caspase 9 and 3.
Glioma
Role of Caspase-9 Gene Ex5+32 G>A (rs1052576) Variant in Susceptibility to Primary Brain Tumors.
Glioma
Synthesis and in vitro evaluation of 4-substituted furano[3,2-c] tetrahydroquinolines as potential anti-cancer agents.
Glioma
T11TS repress gliomagenic apoptosis of bone marrow hematopoietic stem cells.
Glioma
Targeting 14-3-3 protein, difopein induces apoptosis of human glioma cells and suppresses tumor growth in mice.
Glioma
[Evodiamine Promotes Apoptosis of Glioma SHG-44 Cells and Its Mechanism].
Gout
Enhanced p62 Is Responsible for Mitochondrial Pathway-Dependent Apoptosis and Interleukin-1? Production at the Early Phase by Monosodium Urate Crystals in Murine Macrophage.
Graft vs Host Disease
Clonal Dynamics In Vivo of Virus Integration Sites of T Cells Expressing a Safety Switch.
Graft vs Host Disease
Serial Activation of the Inducible Caspase 9 Safety Switch After Human Stem Cell Transplantation.
Gram-Negative Bacterial Infections
Interactions of DNR1 with the apoptotic machinery of Drosophila melanogaster.
Head and Neck Neoplasms
GSTP1 c.313A>G, XPD c.934G>A, XPF c.2505T>C and CASP9 c.-1339A>G Polymorphisms and Severity of Vomiting in Head and Neck Cancer Patients treated with Cisplatin Chemoradiation.
Hearing Loss
Caspase inhibitors, but not c-Jun NH2-terminal kinase inhibitor treatment, prevent cisplatin-induced hearing loss.
Heart Arrest
Therapeutic Hypothermia Enhances Cold-Inducible RNA-Binding Protein Expression and Inhibits Mitochondrial Apoptosis in a Rat Model of Cardiac Arrest.
Hepatic Encephalopathy
Ameliorative effect of Magnesium Isoglycyrrhizinate on hepatic encephalopathy by Epirubicin.
Hepatitis B
Hepatitis B vaccine induces apoptotic death in Hepa1-6 cells.
Hepatitis B
Intrahepatic activation of caspases in human fulminant hepatic failure.
Hepatitis C
Inhibition of hepatitis C virus core protein expression in immortalized human hepatocytes induces cytochrome c-independent increase in Apaf-1 and caspase-9 activation for cell death.
Herpes Simplex
Caspase 9 is essential for herpes simplex virus type 2-induced apoptosis in T cells.
Herpes Simplex
Comparison of different suicide-gene strategies for the safety improvement of genetically manipulated T cells.
Herpes Simplex
Engineered TCR-T Cell Immunotherapy in Anticancer Precision Medicine: Pros and Cons.
Herpes Simplex
Improved safety of induced pluripotent stem cell-derived antigen-presenting cell-based cancer immunotherapy.
Herpes Simplex
Prevention of hepatitis C virus infection by adoptive allogeneic immunotherapy using suicide gene-modified lymphocytes: an in vitro proof-of-concept.
Herpes Simplex
The bovine viral diarrhea virus (BVDV) NS3 protein, when expressed alone in mammalian cells, induces apoptosis which correlates with caspase-8 and caspase-9 activation.
Herpes Simplex
The equine arteritis virus induces apoptosis via caspase-8 and mitochondria-dependent caspase-9 activation.
Histiocytic Sarcoma
The growth of the canine glioblastoma cell line D-GBM and the canine histiocytic sarcoma cell line DH82 is inhibited by the resveratrol oligomers hopeaphenol and r2-viniferin.
Huntington Disease
Cytochrome C and caspase-9 expression in Huntington's disease.
Hyperalgesia
Role of reactive oxygen species and spinal cord apoptotic genes in the development of neuropathic pain.
Hyperglycemia
Impact of hyperglycemia on neuronal apoptosis after subarachnoid hemorrhage in rodent brain: An experimental research.
Hyperhomocysteinemia
Melatonin inhibits neural apoptosis induced by homocysteine in hippocampus of rats via inhibition of cytochrome c translocation and caspase-3 activation and by regulating pro- and anti-apoptotic protein levels.
Hyperlipidemias
[Effect of electroacupuncture on caspase-9 expression in hippocampus and neuroethology in hyperlipemia rats with concurrent cerebral ischemia]
Hypertension
Roles of insulin-like growth factor II in cardiomyoblast apoptosis and in hypertensive rat heart with abdominal aorta ligation.
Hyperthyroidism
Severe hyperthyroidism induces mitochondria-mediated apoptosis in rat liver.
Hypoxia, Brain
ATP and cytochrome c-dependent activation of caspase-9 during hypoxia in the cerebral cortex of newborn piglets.
Hypoxia, Brain
Effect of hypoxia on the expression of procaspase-9 and procaspase-3 in neuronal nuclear, mitochondrial and cytosolic fractions of the cerebral cortex of newborn piglets.
Hypoxia, Brain
Effect of neuronal nitric oxide synthase inhibition on caspase-9 activity during hypoxia in the cerebral cortex of newborn piglets.
Hypoxia, Brain
Hypoxia-induced Bax and Bcl-2 protein expression, caspase-9 activation, DNA fragmentation, and lipid peroxidation in mitochondria of the cerebral cortex of newborn piglets: the role of nitric oxide.
Hypoxia, Brain
Mechanism of activation of caspase-9 and caspase-3 during hypoxia in the cerebral cortex of newborn piglets: the role of nuclear Ca2+ -influx.
Hypoxia, Brain
Mechanism of tyrosine phosphorylation of procaspase-9 and Apaf-1 in cytosolic fractions of the cerebral cortex of newborn piglets during hypoxia.
Infarction, Middle Cerebral Artery
Licorice Pretreatment Protects Against Brain Damage Induced by Middle Cerebral Artery Occlusion in Mice.
Infarction, Middle Cerebral Artery
Permanent cerebral ischemia induces sustained procaspase 9L increase not controlled by Bcl-2.
Infarction, Middle Cerebral Artery
Pien-Tze-Huang protects cerebral ischemic injury by inhibiting neuronal apoptosis in acute ischemic stroke rats.
Infarction, Middle Cerebral Artery
Pinacidil reduces neuronal apoptosis following cerebral ischemia-reperfusion in rats through both mitochondrial and death-receptor signal pathways.
Infarction, Middle Cerebral Artery
Potentiation of Akt and suppression of caspase-9 activations by electroacupuncture after transient middle cerebral artery occlusion in rats.
Infections
5-aza-2'-deoxycytidine upregulates caspase-9 expression cooperating with p53-induced apoptosis in human lung cancer cells.
Infections
Ad-PUMA sensitizes ovarian cancer cells to chemotherapeutic agents.
Infections
Adenovirus type 5 E1A gene therapy for ovarian clear cell carcinoma: a potential treatment strategy.
Infections
Alteration of NF-kappaB activity leads to mitochondrial apoptosis after infection with pathological prion protein.
Infections
An epistatic effect of apaf-1 and caspase-9 on chlamydial infection.
Infections
Anaplasma phagocytophilum delays spontaneous human neutrophil apoptosis by modulation of multiple apoptotic pathways.
Infections
Apoptosis-related gene expression in hamster opisthorchiasis post praziquantel treatment.
Infections
Apoptotic caspases suppress Mycobacterium bovis-induced IFN-? production in murine macrophage.
Infections
Autophagy Delays Apoptotic Cell Death Induced by Siniperca chuatsi Rhabdovirus in Epithelioma Papulosum Cyprinid Cells.
Infections
Bak and Bax function to limit adenovirus replication through apoptosis induction.
Infections
Bidirectional increase in permeability of nuclear envelope upon poliovirus infection and accompanying alterations of nuclear pores.
Infections
Blockade of tumor growth due to matrix metalloproteinase-9 inhibition is mediated by sequential activation of beta1-integrin, ERK, and NF-kappaB.
Infections
Both PI3K- and mTOR-signaling pathways take part in CVB3-induced apoptosis of Hela cells.
Infections
Bovine herpes virus type 1 induces apoptosis through Fas-dependent and mitochondria-controlled manner in Madin-Darby bovine kidney cells.
Infections
Cancer gene therapy using a survivin mutant adenovirus.
Infections
Caspase-9 pathway activation by inhibiting endogenous fibroblast growth factor signaling in human glioma cells.
Infections
Conversion of trichosanthin-induced CD95 (Fas) type I into type II apoptotic signaling during Herpes simplex virus infection.
Infections
Coxsackievirus A16 infection induces neural cell and non-neural cell apoptosis in vitro.
Infections
Crimean-Congo haemorrhagic fever replication interplays with regulation mechanisms of apoptosis.
Infections
Cytosolic phospholipase A2 participates with TNF-alpha in the induction of apoptosis of human macrophages infected with Mycobacterium tuberculosis H37Ra.
Infections
Edwardsiella piscicida type III protein EseJ suppresses apoptosis through down regulating type 1 fimbriae, which stimulate the cleavage of caspase-8.
Infections
Effects of dietary monocalcium phosphate supplementation on the anti-oxidative capacity, anti-bacteria function in immune organs of obscure puffer (Takifugu obscurus) after infection with Aeromonas hydrophila.
Infections
Effects of the PI3K/Akt signaling pathway on the apoptosis of early host cells infected with Eimeria tenella.
Infections
Enterotoxigenic Escherichia coli infection promotes apoptosis in piglets.
Infections
Equine arteritis virus induced cell death is associated with activation of the intrinsic apoptotic signalling pathway.
Infections
Fas/FasL pathway participates in resolution of mucosal inflammatory response early during HSV-2 infection.
Infections
Genetic mechanisms underlying the pathogenicity of cold-stressed Salmonella enterica serovar typhimurium in cultured intestinal epithelial cells.
Infections
Hepatic histopathology and apoptosis in diet-induced-obese mice under Escherichia coli pneumonia.
Infections
HIV-1 Vpr induces apoptosis through caspase 9 in T cells and peripheral blood mononuclear cells.
Infections
Human coronavirus-induced neuronal programmed cell death is cyclophilin d dependent and potentially caspase dispensable.
Infections
Identification of Chlamydia pneumoniae candidate genes that interact with human apoptotic factor caspase-9.
Infections
Impaired hepatitis C virus (HCV)-specific effector CD8+ T cells undergo massive apoptosis in the peripheral blood during acute HCV infection and in the liver during the chronic phase of infection.
Infections
Implication of caspases during maedi-visna virus-induced apoptosis.
Infections
In vitro infection of bovine monocytes with Mycoplasma bovis delays apoptosis and suppresses production of gamma interferon and tumor necrosis factor alpha but not interleukin-10.
Infections
Induction of apoptosis in SSN-1cells by Snakehead Fish Vesiculovirus (SHVV) via Matrix protein dependent intrinsic pathway.
Infections
Induction of apoptosis limits cytomegalovirus cross-species infection.
Infections
Intrinsic apoptosis and cytokine induction regulated in human tonsillar epithelial cells infected with enterovirus A71.
Infections
Intrinsic apoptosis and proinflammatory cytokines regulated in human astrocytes infected with enterovirus 71.
Infections
Involvement of caspase activation through release of cytochrome c from mitochondria in apoptotic cell death of macrophages infected with Actinobacillus actinomycetemcomitans.
Infections
Involvement of caspase-9 in the inhibition of necrosis of RAW 264 cells infected with Mycobacterium tuberculosis.
Infections
Involvement of the PI3K and ERK signaling pathways in largemouth bass virus-induced apoptosis and viral replication.
Infections
Japanese encephalitis virus infection activates caspase-8 and -9 in a FADD-independent and mitochondrion-dependent manner.
Infections
Life as a Vector of Dengue Virus: The Antioxidant Strategy of Mosquito Cells to Survive Viral Infection.
Infections
Lung epithelial cells resist influenza A infection by inducing the expression of cytochrome c oxidase VIc which is modulated by miRNA 4276.
Infections
Malarial infection develops mitochondrial pathology and mitochondrial oxidative stress to promote hepatocyte apoptosis.
Infections
Modulation of apoptosis by caprine herpesvirus 1 infection in a neuronal cell line.
Infections
Mycobacterium bovis Induces Endoplasmic Reticulum Stress Mediated-Apoptosis by Activating IRF3 in a Murine Macrophage Cell Line.
Infections
Overexpression of 4EBP1, p70S6K, Akt1 or Akt2 differentially promotes Coxsackievirus B3-induced apoptosis in HeLa cells.
Infections
Overexpression of interferon-gamma-inducible GTPase inhibits coxsackievirus B3-induced apoptosis through the activation of the phosphatidylinositol 3-kinase/Akt pathway and inhibition of viral replication.
Infections
Parents of ataxia-telangiectasia patients display a distinct cellular immune phenotype mimicking ATM mutated patients.
Infections
Phosphoprotein Gene Contributes to the Enhanced Apoptosis Induced by Wild-Type Rabies Virus GD-SH-01 In Vitro.
Infections
Phosphorylation of PI3K/Akt and MAPK/ERK in an early entry step of enterovirus 71.
Infections
Porcine deltacoronavirus induces caspase-dependent apoptosis through activation of the cytochrome c-mediated intrinsic mitochondrial pathway.
Infections
Porcine parvovirus infection activates mitochondria-mediated apoptotic signaling pathway by inducing ROS accumulation.
Infections
Porcine reproductive and respiratory syndrome virus induces apoptosis through a mitochondria-mediated pathway.
Infections
Porphyromonas gingivalis infection sequesters pro-apoptotic Bad through Akt in primary gingival epithelial cells.
Infections
Protection against CD95-induced apoptosis by chlamydial infection at a mitochondrial step.
Infections
Proteolysis of Pseudomonas exotoxin A within hepatic endosomes by cathepsins B and D produces fragments displaying in vitro ADP-ribosylating and apoptotic effects.
Infections
Relationship between Eimeria tenella development and host cell apoptosis in chickens.
Infections
Reovirus-induced neuronal apoptosis is mediated by caspase 3 and is associated with the activation of death receptors.
Infections
Role of the mitochondrial signaling pathway in murine coronavirus-induced oligodendrocyte apoptosis.
Infections
Selenium Plays a Protective Role in Staphylococcus aureus-Induced Endometritis in the Uterine Tissue of Rats.
Infections
Streptococcus pyogenes serotype-dependent and independent changes in infected HEp-2 epithelial cells.
Infections
The African swine fever virus dynein-binding protein p54 induces infected cell apoptosis.
Infections
The Culicoides sonorensis inhibitor of apoptosis 1 protein protects mammalian cells from apoptosis induced by infection with African horse sickness virus and bluetongue virus.
Infections
The HIV-1-Specific Protein Casp8p41 Induces Death of Infected Cells through Bax/Bak.
Infections
The JAK/STAT3 signaling pathway mediates inhibition of host cell apoptosis by Chlamydia psittaci infection.
Infections
The latency-related gene encoded by bovine herpesvirus 1 can suppress caspase 3 and caspase 9 cleavage during productive infection.
Infections
The major apoptotic pathway activated and suppressed by poliovirus.
Infections
The Megalocytivirus RBIV Induces Apoptosis and MHC Class I Presentation in Rock Bream (Oplegnathus fasciatus) Red Blood Cells.
Infections
Transmissible gastroenteritis virus infection induces apoptosis through FasL- and mitochondria-mediated pathways.
Infections
Vesicular stomatitis viruses expressing wild-type or mutant M proteins activate apoptosis through distinct pathways.
Infections
[Porcine deltacoronavirus induces mitochondrial apoptosis in ST cells].
Infertility, Male
The Role of Protamine 2 Gene Expression and Caspase 9 Activity in Male Infertility.
Inflammatory Bowel Diseases
Association of caspase-9 and RUNX3 with inflammatory bowel disease.
Influenza, Human
Alpha/beta interferons potentiate virus-induced apoptosis through activation of the FADD/Caspase-8 death signaling pathway.
Influenza, Human
Influenza A Virus and Influenza B Virus Can Induce Apoptosis via Intrinsic or Extrinsic Pathways and Also via NF-?B in a Time and Dose Dependent Manner.
Influenza, Human
Lung epithelial cells resist influenza A infection by inducing the expression of cytochrome c oxidase VIc which is modulated by miRNA 4276.
Influenza, Human
[Antagonism of baicalin on cell cyclical distribution and cell apoptosis in A549 cells infected with influenza A (H1N1) virus].
Insulinoma
Photoactivation of hypericin decreases the viability of RINm5F insulinoma cells through reduction of JNK/ERK phosphorylation and elevation of caspase-9/caspase-3 cleavage and Bax-to-Bcl-2 ratio.
Intervertebral Disc Degeneration
Caspase 9 gene polymorphism and susceptibility to lumbar disc disease in the Han population in northern China.
Intervertebral Disc Degeneration
Paeoniflorin inhibits nucleus pulposus cell apoptosis by regulating the expression of Bcl-2 family proteins and caspase-9 in a rabbit model of intervertebral disc degeneration.
Intervertebral Disc Degeneration
Role of the mitochondrial pathway in serum deprivation-induced apoptosis of rat endplate cells.
Intervertebral Disc Degeneration
[Caspase-9 (-Ex5+32 G/A) gene polymorphism is associated with caspase-9 expression in degenerative nucleus pulposus of lumbar intervertebral disc].
Intervertebral Disc Displacement
Caspase 9 gene polymorphism and susceptibility to lumbar disc disease in the Han population in northern China.
Intervertebral Disc Displacement
Evaluation of the association between biochemical and immunohistochemical score of caspase-9 and TNF?, and the grading of lumbar disc herniation.
Iron Overload
Antiapoptotic effects of cannabidiol in an experimental model of cognitive decline induced by brain iron overload.
Ischemic Attack, Transient
Cloning and characterization of rat caspase-9: implications for a role in mediating caspase-3 activation and hippocampal cell death after transient cerebral ischemia.
Ischemic Attack, Transient
The effect of low-energy laser irradiation on apoptotic factors following experimentally induced transient cerebral ischemia.
Ischemic Attack, Transient
Treatment with the glycogen synthase kinase-3beta inhibitor, TDZD-8, affects transient cerebral ischemia/reperfusion injury in the rat hippocampus.
Ischemic Stroke
Association Between a Polymorphism in CASP3 and CASP9 Genes and Ischemic Stroke.
Ischemic Stroke
Pien-Tze-Huang protects cerebral ischemic injury by inhibiting neuronal apoptosis in acute ischemic stroke rats.
Keloid
A comparison expression analysis of CXCR4, CXCL9 and Caspase-9 in dermal vascular endothelial cells between keloids and normal skin on chemotaxis and apoptosis.
Keloid
Activated caspase expression and apoptosis increase in keloids: cytochrome c release and caspase-9 activation during the apoptosis of keloid fibroblast lines.
Ketosis
Oxidative stress, NF-?B signaling, NLRP3 inflammasome, and caspase apoptotic pathways are activated in mammary gland of ketotic Holstein cows.
Laryngeal Neoplasms
Inhibition of caspase-9 by oridonin, a diterpenoid isolated from Rabdosia rubescens, augments apoptosis in human laryngeal cancer cells.
Leiomyoma
Gyejibongnyeong-Hwan (Gui Zhi Fu Ling Wan) Ameliorates Human Uterine Myomas via Apoptosis.
Leiomyoma
[Expression of caspase 9 and p53 in uterine leiomyosarcomas].
Leiomyosarcoma
[Expression of caspase 9 and p53 in uterine leiomyosarcomas].
Leukemia
A112, a tamibarotene dimethylaminoethyl ester, may inhibit human leukemia cell growth more potently than tamibarotene.
Leukemia
Ampelopsin Inhibits Cell Proliferation and Induces Apoptosis in HL60 and K562 Leukemia Cells by Downregulating AKT and NF-?B Signaling Pathways.
Leukemia
Apoptosis induced by protein phosphatase 2A (PP2A) inhibition in T leukemia cells is negatively regulated by PP2A-associated p38 mitogen-activated protein kinase.
Leukemia
Apoptosis induced by the kinase inhibitor BAY 43-9006 in human leukemia cells involves down-regulation of Mcl-1 through inhibition of translation.
Leukemia
Apoptotic Effect of Galbanic Acid via Activation of Caspases and Inhibition of Mcl-1 in H460 Non-Small Lung Carcinoma Cells.
Leukemia
Auraptene Induces Apoptosis via Myeloid Cell Leukemia 1-Mediated Activation of Caspases in PC3 and DU145 Prostate Cancer Cells.
Leukemia
Bovine lactoferricin selectively induces apoptosis in human leukemia and carcinoma cell lines.
Leukemia
Breaking chemoresistance and radioresistance with [213Bi]anti-CD45 antibodies in leukemia cells.
Leukemia
Cadmium induces apoptosis partly via caspase-9 activation in HL-60 cells.
Leukemia
Caspase-9 is the upstream caspase activated by 8-methoxypsoralen and ultraviolet-A radiation treatment of Jurkat T leukemia cells and normal T lymphocytes.
Leukemia
Compound K induced apoptosis via endoplasmic reticulum Ca2+ release through ryanodine receptor in human lung cancer cells.
Leukemia
Dietary docosahexaenoic acid decreased lipid accumulation via inducing adipocytes apoptosis of grass carp, Ctenopharygodon idella.
Leukemia
Discovery of Sanggenon G as a natural cell-permeable small-molecular weight inhibitor of X-linked inhibitor of apoptosis protein (XIAP).
Leukemia
Effects of AG490 and S3I-201 on regulation of the JAK/STAT3 signaling pathway in relation to angiogenesis in TRAIL-resistant prostate cancer cells in vitro.
Leukemia
Hyperforin a constituent of St John's wort (Hypericum perforatum L.) extract induces apoptosis by triggering activation of caspases and with hypericin synergistically exerts cytotoxicity towards human malignant cell lines.
Leukemia
Inducing cell proliferative prevention in human acute promyelocytic leukemia by miR-182 inhibition through modulation of CASP9 expression.
Leukemia
Induction of endoplasmic reticulum stress and apoptosis by a marine prostanoid in human hepatocellular carcinoma.
Leukemia
Inhibition of nitric-oxide-mediated apoptosis in Jurkat leukemia cells despite cytochrome c release.
Leukemia
Integrin-linked kinase interacts with caspase-9 and -8 in an adhesion-dependent manner for promoting radiation-induced apoptosis in human leukemia cells.
Leukemia
Loss of mitochondrial transmembrane potential and caspase-9 activation during apoptosis induced by the novel styryl-lactone goniothalamin in HL-60 leukemia cells.
Leukemia
Methadone, commonly used as maintenance medication for outpatient treatment of opioid dependence, kills leukemia cells and overcomes chemoresistance.
Leukemia
Methylene chloride fraction of Scutellaria barbata induces apoptosis in human U937 leukemia cells via the mitochondrial signaling pathway.
Leukemia
Molecular mechanism of satratoxin-induced apoptosis in HL-60 cells: activation of caspase-8 and caspase-9 is involved in activation of caspase-3.
Leukemia
Monoterpenes as drug shuttles: cytotoxic (6-aminomethylnicotinate)dichloridoplatinum(II) complexes with potential to overcome cisplatin resistance.
Leukemia
Naringenin-induced apoptosis is attenuated by Bcl-2 but restored by the small molecule Bcl-2 inhibitor, HA 14-1, in human leukemia U937 cells.
Leukemia
Ordering of ceramide formation and caspase-9 activation in CD95L-induced Jurkat leukemia T cell apoptosis.
Leukemia
Pyrrolidine dithiocarbamate inhibition of luteolin-induced apoptosis through up-regulated phosphorylation of Akt and caspase-9 in human leukemia HL-60 cells.
Leukemia
Pyrrolo[1,2-b][1,2,5]benzothiadiazepines (PBTDs) exert their anti-proliferative activity by interfering with Akt-mTOR signaling and bax:bcl-2 ratio modulation in cells from chronic myeloid leukemic patients.
Leukemia
Radiation-induced apoptosis is independent of caspase-8 but dependent on cytochrome c and the caspase-9 cascade in human leukemia HL60 cells.
Leukemia
Resveratrol analogue (E)-8-acetoxy-2-[2-(3,4-diacetoxyphenyl)ethenyl]-quinazoline induces apoptosis via Fas-mediated pathway in HL-60 human leukemia cells.
Leukemia
Resveratrol enhances anticancer effects of paclitaxel in HepG2 human liver cancer cells.
Leukemia
Tanshinone IIA inhibits human gastric carcinoma AGS cell growth by decreasing BiP, TCTP, Mcl?1 and Bcl?xL and increasing Bax and CHOP protein expression.
Leukemia
The mechanism of tumor cell clearance by rituximab in vivo in patients with B-cell chronic lymphocytic leukemia: evidence of caspase activation and apoptosis induction.
Leukemia
The non-apoptotic role of caspase-9 promotes differentiation in leukemic cells.
Leukemia
The possibility of simvastatin as a chemotherapeutic agent for all-trans retinoic acid-resistant promyelocytic leukemia.
Leukemia
Xanthohumol inhibits proliferation of laryngeal squamous cell carcinoma.
Leukemia
[BMMSC from blastic phase CML down-regulate leukemia cell apoptosis].
Leukemia
[Effects of SODD and survivin on leukemia cell apoptosis induced by chemotherapeutic drugs]
Leukemia
[Role of High Mobility Group Box 1 in Adriamycin-induced Apoptosis in Leukemia K562 Cells.]
Leukemia
[The mechanism for SHIP gene to induce the apoptosis of human leukemia cell line K562.]
Leukemia, B-Cell
Apoptosis in meningoencephalitis of Angiostrongylus cantonensis-infected mice.
Leukemia, B-Cell
Dietary docosahexaenoic acid decreased lipid accumulation via inducing adipocytes apoptosis of grass carp, Ctenopharygodon idella.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
3,5-dibenzyloxy-4'-hydroxystilbene induces early caspase-9 activation during apoptosis in human K562 chronic myelogenous leukemia cells.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Pyrrolo[1,2-b][1,2,5]benzothiadiazepines (PBTDs) exert their anti-proliferative activity by interfering with Akt-mTOR signaling and bax:bcl-2 ratio modulation in cells from chronic myeloid leukemic patients.
Leukemia, Myeloid
The Effect of Bornyl cis-4-Hydroxycinnamate on Melanoma Cell Apoptosis Is Associated with Mitochondrial Dysfunction and Endoplasmic Reticulum Stress.
Leukemia, Myeloid
[Apoptosis of myeloid leukemia cell line HL60 induced by Bortezomib, a proteasome inhibitor]
Leukemia, Myeloid, Acute
A CD33 Antigen-Targeted AAV6 Vector Expressing an Inducible Caspase-9 Suicide Gene Is Therapeutic in a Xenotransplantation Model of Acute Myeloid Leukemia.
Leukemia, Myeloid, Acute
Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells.
Leukemia, Promyelocytic, Acute
Inducing cell proliferative prevention in human acute promyelocytic leukemia by miR-182 inhibition through modulation of CASP9 expression.
Leukemia, Promyelocytic, Acute
Induction of endoplasmic reticulum stress and apoptosis by a marine prostanoid in human hepatocellular carcinoma.
Liver Diseases
Carbon monoxide blocks oxidative stress-induced hepatocyte apoptosis via inhibition of the p54 JNK isoform.
Liver Neoplasms
Demethylation of miR-34a upregulates expression of membrane palmitoylated proteins and promotes the apoptosis of liver cancer cells.
Liver Neoplasms
Effects of matrine in combination with cisplatin on liver cancer.
Liver Neoplasms
Effects of melanoma differentiation associated gene-7 (MDA-7/IL-24) on apoptosis of liver cancer cells via regulating the expression of B-cell lymphoma-2.
Liver Neoplasms
Ellagic acid normalizes mitochondrial outer membrane permeabilization and attenuates inflammation-mediated cell proliferation in experimental liver cancer.
Liver Neoplasms
Pitavastatin suppressed liver cancer cells in vitro and in vivo.
Liver Neoplasms
Quercetin nanoparticles display antitumor activity via proliferation inhibition and apoptosis induction in liver cancer cells.
Liver Neoplasms
Silencing of WWP2 inhibits adhesion, invasion, and migration in liver cancer cells.
Liver Neoplasms
The bioactive ingredients in Actinidia chinensis Planch. Inhibit liver cancer by inducing apoptosis.
Lung Injury
Restoring microRNA-499-5p Protects Sepsis-Induced Lung Injury Mice Via Targeting Sox6.
Lung Injury
[Protective effects of dexmedetomidine against pulmonary ischemia-reperfusion injury during cardiopulmonary bypass in rats].
Lung Neoplasms
5-aza-2'-deoxycytidine upregulates caspase-9 expression cooperating with p53-induced apoptosis in human lung cancer cells.
Lung Neoplasms
?-Hydroxyundec-9-enoic acid induces apoptosis through ROS-mediated endoplasmic reticulum stress in non-small cell lung cancer cells.
Lung Neoplasms
A facile approach for fabricating CD44-targeted delivery of hyaluronic acid-functionalized PCL nanoparticles in urethane-induced lung cancer: Bcl-2, MMP-9, caspase-9, and BAX as potential markers.
Lung Neoplasms
A literature-based systematic HuGE review and meta-analysis show that CASP gene family polymorphisms are associated with risk of lung cancer.
Lung Neoplasms
Activation of mitochondrial pathway is crucial for tumor selective induction of apoptosis by LAQ824.
Lung Neoplasms
Altered expression profile of apoptosis-related molecules correlated with clinicopathological factors in non-small-cell lung cancer.
Lung Neoplasms
Alternative Splicing of Caspase 9 Is Modulated by the Phosphoinositide 3-Kinase/Akt Pathway via Phosphorylation of SRp30a.
Lung Neoplasms
Antitumor activity of 4-O-(2?-O-acetyl-6?-O-p-coumaroyl-?-D-glucopyranosyl)-p-coumaric acid against lung cancers via mitochondrial-mediated apoptosis.
Lung Neoplasms
ASH1 gene is a specific therapeutic target for lung cancers with neuroendocrine features.
Lung Neoplasms
Bik/NBK accumulation correlates with apoptosis-induction by bortezomib (PS-341, Velcade) and other proteasome inhibitors.
Lung Neoplasms
Caspase 9 promoter polymorphisms and risk of primary lung cancer.
Lung Neoplasms
Chemosensitizing effect of Paris Saponin I on Camptothecin and 10-hydroxycamptothecin in lung cancer cells via p38 MAPK, ERK, and Akt signaling pathways.
Lung Neoplasms
COL11A1 Was Involved in Cell Proliferation, Apoptosis and Migration in Non-Small Cell Lung Cancer Cells.
Lung Neoplasms
Correction to: a facile approach for fabricating CD44-targeted delivery of hyaluronic acid-functionalized PCL nanoparticles in urethane-induced lung cancer: Bcl-2, MMP-9, caspase-9, and BAX as potential markers.
Lung Neoplasms
Cytotoxic effects of Pseudocerastes persicus venom and its HPLC fractions on lung cancer cells.
Lung Neoplasms
Defective caspase-3 relocalization in non-small cell lung carcinoma.
Lung Neoplasms
Effects and mechanism of downregulation of survivin expression by RNA interference on proliferation and apoptosis of lung cancer cells.
Lung Neoplasms
Effects of Selenium Nanoparticles Combined With Radiotherapy on Lung Cancer Cells.
Lung Neoplasms
Expression and prognostic significance of osteopontin and caspase-3 in hepatocellular carcinoma patients after curative resection.
Lung Neoplasms
Extract of Calvatia gigantea inhibits proliferation of A549 human lung cancer cells.
Lung Neoplasms
hnRNP L regulates the tumorigenic capacity of lung cancer xenografts in mice via caspase-9 pre-mRNA processing.
Lung Neoplasms
Investigation of Caspase 9 Gene Polymorphism in Patients With Non-small Cell Lung Cancer.
Lung Neoplasms
MicroRNA-145 replacement effect on growth and migration inhibition in lung cancer cell line.
Lung Neoplasms
miR-1269 promotes cell survival and proliferation by targeting tp53 and caspase-9 in lung cancer.
Lung Neoplasms
Osthole extracted from a citrus fruit that affects apoptosis on A549 cell line by histone deacetylasese inhibition (HDACs).
Lung Neoplasms
Overexpression of smac promotes Cisplatin-induced apoptosis by activating caspase-3 and caspase-9 in lung cancer a549 cells.
Lung Neoplasms
Plumbagin engenders apoptosis in lung cancer cells via caspase-9 activation and targeting mitochondrial-mediated ROS induction.
Lung Neoplasms
Polymorphisms in the caspase genes and the risk of lung cancer.
Lung Neoplasms
Prodrug-Like, PEGylated Protein Toxin Trichosanthin for Reversal of Chemoresistance.
Lung Neoplasms
Prognostic assessment of apoptotic gene polymorphisms in non-small cell lung cancer in Chinese.
Lung Neoplasms
Purpurin, a anthraquinone induces ROS-mediated A549 lung cancer cell apoptosis via inhibition of PI3K/AKT and proliferation.
Lung Neoplasms
RNAi targeting STMN alleviates the resistance to taxol and collectively contributes to down regulate the malignancy of NSCLC cells in vitro and in vivo.
Lung Neoplasms
Role of XIAP in inhibiting cisplatin-induced caspase activation in non-small cell lung cancer cells: a small molecule Smac mimic sensitizes for chemotherapy-induced apoptosis by enhancing caspase-3 activation.
Lung Neoplasms
SRSF1 Regulates the Alternative Splicing of Caspase 9 Via A Novel Intronic Splicing Enhancer Affecting the Chemotherapeutic Sensitivity of Non-Small Cell Lung Cancer Cells.
Lung Neoplasms
Suberoylanilide hydroxamic acid increases anti-cancer effect of tumor necrosis factor-? through up-regulation of TNF receptor 1 in lung cancer cells.
Lung Neoplasms
Sulforaphane-induced apoptosis in Xuanwei lung adenocarcinoma cell line XWLC-05.
Lung Neoplasms
Sulindac enhances adenoviral vector expressing mda-7/IL-24-mediated apoptosis in human lung cancer.
Lung Neoplasms
Suppressing effects of daily oral supplementation of beta-glucan extracted from Agaricus blazei Murill on spontaneous and peritoneal disseminated metastasis in mouse model.
Lung Neoplasms
The caspase 9 inhibitor Z-LEHD-FMK protects human liver cells while permitting death of cancer cells exposed to tumor necrosis factor-related apoptosis-inducing ligand.
Lung Neoplasms
The tumor suppressor gene RBM5 inhibits lung adenocarcinoma cell growth and induces apoptosis.
Lung Neoplasms
TIPE2 Inhibits Lung Cancer Growth Attributing to Promotion of Apoptosis by Regulating Some Apoptotic Molecules Expression.
Lung Neoplasms
Yap-Hippo promotes A549 lung cancer cell death via modulating MIEF1-related mitochondrial stress and activating JNK pathway.
Lung Neoplasms
[A study on the expression of CASP9 gene and its polymorphism distribution in non-small cell lung cancer]
Lupus Erythematosus, Systemic
Investigation of the caspase-dependent mitochondrial apoptotic pathway in mononuclear cells of patients with systemic lupus erythematosus.
Lymphatic Metastasis
EMP1 regulates caspase-9 and VEGFC expression and suppresses prostate cancer cell proliferation and invasion.
Lymphatic Metastasis
EMP1, a member of a new family of antiproliferative genes in breast carcinoma.
Lymphatic Metastasis
[A study on the expression of CASP9 gene and its polymorphism distribution in non-small cell lung cancer]
Lymphatic Metastasis
[Expressions and clinical significances of iASPP and caspase-9 in esophageal cancer].
Lymphoma
A B-Cell Superantigen Induces the Apoptosis of Murine and Human Malignant B Cells.
Lymphoma
A computational and functional study elicits the ameliorating effect of the Chinese herbal formula Huo Luo Xiao Ling Dan on experimental ischemia-induced myocardial injury in rats via inhibition of apoptosis.
Lymphoma
A Litopenaeus vannamei Hemocyanin-Derived Antimicrobial Peptide (Peptide B11) Attenuates Cancer Cells' Proliferation.
Lymphoma
Anticancer Effect of Ursodeoxycholic Acid in Human Oral Squamous Carcinoma HSC-3 Cells through the Caspases.
Lymphoma
Apaf-1 and caspase-9 do not act as tumor suppressors in myc-induced lymphomagenesis or mouse embryo fibroblast transformation.
Lymphoma
Bone morphogenetic protein 9 facilitates osteocarcinoma cell apoptosis and inhibits in vivo tumor growth.
Lymphoma
Characterization of antiapoptotic microRNAs in primary Sjögren's syndrome.
Lymphoma
Combining a CD20 chimeric antigen receptor and an inducible caspase 9 suicide switch to improve the efficacy and safety of T cell adoptive immunotherapy for lymphoma.
Lymphoma
Dimethyl sulfoxide activates tumor necrosis factor?-p53 mediated apoptosis and down regulates d-fructose-6-phosphate-2-kinase and lactate dehydrogenase-5 in Dalton's lymphoma in vivo.
Lymphoma
Dissecting p53 tumor suppressor functions in vivo.
Lymphoma
Furosine Induced Apoptosis by the Regulation of STAT1/STAT2 and UBA7/UBE2L6 Genes in HepG2 Cells.
Lymphoma
Hesperetin induces apoptosis of esophageal cancer cells via mitochondrial pathway mediated by the increased intracellular reactive oxygen species.
Lymphoma
Inert ruthenium half-sandwich complexes with anticancer activity.
Lymphoma
Inhibition of caspase 9 and not caspase 8 mediated apoptosis may determine clinical response to chemotherapy in primary nodal diffuse large B-cell lymphomas.
Lymphoma
Involvement of mitochondrial permeability transition and caspase-9 activation in dimethyl sulfoxide-induced apoptosis of EL-4 lymphoma cells.
Lymphoma
Long-term beneficial effect of protease inhibitors on the intrinsic apoptosis of peripheral blood mononuclear cells in HIV-infected patients.
Lymphoma
Mitochondria-dependent caspase-9 activation is necessary for antigen receptor-mediated effector caspase activation and apoptosis in WEHI 231 lymphoma cells.
Lymphoma
Motexafin gadolinium induces mitochondrially-mediated caspase-dependent apoptosis.
Lymphoma
Pien Tze Huang induces apoptosis and inhibits proliferation of 5-fluorouracil-resistant colorectal carcinoma cells via increasing miR-22 expression.
Lymphoma
Protective effects elicited by levosimendan against liver ischemia/reperfusion injury in anesthetized rats.
Lymphoma
Pyrrolidinium fullerene induces apoptosis by activation of procaspase-9 via suppression of Akt in primary effusion lymphoma.
Lymphoma
Qilin pills alleviate oligoasthenospermia by inhibiting Bax-caspase-9 apoptosis pathway in the testes of model rats.
Lymphoma
Regulation of the expression of caspase-9 by the transcription factor activator protein-4 in glucocorticoid-induced apoptosis.
Lymphoma
Shikonin Exerts Cytotoxic Effects in Human Colon Cancers by Inducing Apoptotic Cell Death via the Endoplasmic Reticulum and Mitochondria-Mediated Pathways.
Lymphoma
Sialic acids linked to glycoconjugates of Fas regulate the caspase-9-dependent and mitochondria-mediated pathway of Fas-induced apoptosis in Jurkat T cell lymphoma.
Lymphoma
Taurine chloramine, an oxidant derived from neutrophils, induces apoptosis in human B lymphoma cells through mitochondrial damage.
Lymphoma
The cardioprotective effects of diallyl trisulfide on diabetic rats with ex vivo induced ischemia/reperfusion injury.
Lymphoma
The heat shock protein 90 inhibitor 17-AAG induces cell cycle arrest and apoptosis in mantle cell lymphoma cell lines by depleting cyclin D1, Akt, Bid and activating caspase 9.
Lymphoma
The histone deacetylase inhibitors LAQ824 and LBH589 do not require death receptor signaling or a functional apoptosome to mediate tumor cell death or therapeutic efficacy.
Lymphoma
The Inhibition Effect of the Seaweed Polyphenol, 7-Phloro-Eckol from Ecklonia Cava on Alcohol-Induced Oxidative Stress in HepG2/CYP2E1 Cells.
Lymphoma
The Protective Role of Selenium Against AFB1-Induced Liver Apoptosis by Death Receptor Pathway in Broilers.
Lymphoma
Triggering of a novel intrinsic apoptosis pathway by the kinase inhibitor staurosporine: activation of caspase-9 in the absence of Apaf-1.
Lymphoma
Upregulation of phosphatase and tensin homolog is essential for the effect of 4-aminopyridine on A549/CDDP cells.
Lymphoma, B-Cell
9-cis retinoic acid inhibits cumulus cell apoptosis during the maturation of bovine cumulus-oocyte-complexes.
Lymphoma, B-Cell
A computational and functional study elicits the ameliorating effect of the Chinese herbal formula Huo Luo Xiao Ling Dan on experimental ischemia-induced myocardial injury in rats via inhibition of apoptosis.
Lymphoma, B-Cell
A Novel Oral Astaxanthin Nanoemulsion from Haematococcus pluvialis Induces Apoptosis in Lung Metastatic Melanoma.
Lymphoma, B-Cell
Adenovirus-directed expression of TIPE2 suppresses gastric cancer growth via induction of apoptosis and inhibition of AKT and ERK1/2 signaling.
Lymphoma, B-Cell
Aloe-emodin induces cell death through S-phase arrest and caspase-dependent pathways in human tongue squamous cancer SCC-4 cells.
Lymphoma, B-Cell
Altered apoptosis-related signaling after cardioplegic arrest in patients with uncontrolled type 2 diabetes mellitus.
Lymphoma, B-Cell
Ammonia inhalation impaired immune function and mitochondrial integrity in the broilers bursa of fabricius: Implication of oxidative stress and apoptosis.
Lymphoma, B-Cell
An active molecule from Pulsatilla chinensis, Pulsatilla saponin A, induces apoptosis and inhibits tumor growth of human colon cancer cells without or with 5-FU.
Lymphoma, B-Cell
Anguilla japonica lectin 1 delivery through adenovirus vector induces apoptotic cancer cell death through interaction with PRMT5.
Lymphoma, B-Cell
Anti-Condyloma acuminata mechanism of microRNAs-375 modulates HPV in cervical cancer cells via the UBE3A and IGF-1R pathway.
Lymphoma, B-Cell
Anti-Proliferative and Apoptotic Activities of Müllerian Inhibiting Substance Combined with Calcitriol in Ovarian Cancer Cell Lines.
Lymphoma, B-Cell
Anticancer effect of inactivated Sendai virus strain Tianjin on human osteosarcoma HOS cells.
Lymphoma, B-Cell
Anticancer effects of ?-elemene with hyperthermia in lung cancer cells.
Lymphoma, B-Cell
Antitumor and Apoptosis-inducing Effects of Piperine on Human Melanoma Cells.
Lymphoma, B-Cell
Antitumor effect of forbesione isolated from Garcinia hanburyi on cholangiocarcinoma in vitro and in vivo.
Lymphoma, B-Cell
Apatinib suppresses the Proliferation and Apoptosis of Gastric Cancer Cells via the PI3K/Akt Signaling Pathway.
Lymphoma, B-Cell
Apoptosis in temporomandibular joint disc with internal derangement involves mitochondrial-dependent pathways. An in vivo study.
Lymphoma, B-Cell
Bardoxolone methyl induces apoptosis and autophagy and inhibits epithelial-to-mesenchymal transition and stemness in esophageal squamous cancer cells.
Lymphoma, B-Cell
Biological activity of Brassica rapa L. polysaccharides on RAW264.7 macrophages and on tumor cells.
Lymphoma, B-Cell
Calf Spleen Extractive Injection (CSEI), a small peptides enriched extraction, induces human hepatocellular carcinoma cell apoptosis via ROS/MAPKs dependent mitochondrial pathway.
Lymphoma, B-Cell
Characterization and anti-tumor activity of saponin-rich fractions of South Korean sea cucumbers (Apostichopus japonicus).
Lymphoma, B-Cell
Characterization of antiapoptotic microRNAs in primary Sjögren's syndrome.
Lymphoma, B-Cell
Characterization of Apoptosis in a Breast Cancer Cell Line after IL-10 Silencing
Lymphoma, B-Cell
Chlorpyrifos induced oxidative stress to promote apoptosis and autophagy through the regulation of miR-19a-AMPK axis in common carp.
Lymphoma, B-Cell
Cicadidae Periostracum, the Cast-Off Skin of Cicada, Protects Dopaminergic Neurons in a Model of Parkinson's Disease.
Lymphoma, B-Cell
Cordycepin, a Natural Antineoplastic Agent, Induces Apoptosis of Breast Cancer Cells via Caspase-dependent Pathways.
Lymphoma, B-Cell
Cypermethrin Alters the Expression Profile of mRNAs in the Adult Rat Striatum: A Putative Mechanism of Postnatal Pre-exposure Followed by Adulthood Re-exposure-Enhanced Neurodegeneration.
Lymphoma, B-Cell
Cysteine-conjugated metabolites of ginger components, shogaols, induce apoptosis through oxidative stress-mediated p53 pathway in human colon cancer cells.
Lymphoma, B-Cell
Deficiency of dietary pyridoxine disturbed the intestinal physical barrier function of young grass carp (Ctenopharyngodon idella).
Lymphoma, B-Cell
Demethylation of miR-34a upregulates expression of membrane palmitoylated proteins and promotes the apoptosis of liver cancer cells.
Lymphoma, B-Cell
Development of an alternative zebrafish model for drug-induced intestinal toxicity.
Lymphoma, B-Cell
Differential regulation of caspase-9 by ionizing radiation- and UV-induced apoptotic pathways in thymic cells.
Lymphoma, B-Cell
Duhuo Jisheng decoction treatment inhibits the sodium nitroprussiate?induced apoptosis of chondrocytes through the mitochondrial?dependent signaling pathway.
Lymphoma, B-Cell
Effects of dietary monocalcium phosphate supplementation on the anti-oxidative capacity, anti-bacteria function in immune organs of obscure puffer (Takifugu obscurus) after infection with Aeromonas hydrophila.
Lymphoma, B-Cell
Effects of ELL-associated factor 2 on ultraviolet radiation-induced cataract formation in mice.
Lymphoma, B-Cell
Epigallocatechin-3-gallate protects against hepatic ischaemia-reperfusion injury by reducing oxidative stress and apoptotic cell death.
Lymphoma, B-Cell
Eugenol Exerts Apoptotic Effect and Modulates the Sensitivity of HeLa Cells to Cisplatin and Radiation.
Lymphoma, B-Cell
Fomes fomentarius Ethanol Extract Exerts Inhibition of Cell Growth and Motility Induction of Apoptosis via Targeting AKT in Human Breast Cancer MDA-MB-231 Cells.
Lymphoma, B-Cell
Galbanic acid potentiates TRAIL induced apoptosis in resistant non-small cell lung cancer cells via inhibition of MDR1 and activation of caspases and DR5.
Lymphoma, B-Cell
Ginkgo biloba Extract EGb761 Attenuates Bleomycin-Induced Experimental Pulmonary Fibrosis in Mice by Regulating the Balance of M1/M2 Macrophages and Nuclear Factor Kappa B (NF-?B)-Mediated Cellular Apoptosis.
Lymphoma, B-Cell
Hesperetin induces apoptosis of esophageal cancer cells via mitochondrial pathway mediated by the increased intracellular reactive oxygen species.
Lymphoma, B-Cell
Hesperetin Promotes Cisplatin-Induced Apoptosis of Gastric Cancer In Vitro and In Vivo by Upregulating PTEN Expression.
Lymphoma, B-Cell
Hesperidin Attenuates Ultraviolet B-Induced Apoptosis by Mitigating Oxidative Stress in Human Keratinocytes.
Lymphoma, B-Cell
HSP70/HSP90-Organizing Protein Contributes to Gastric Cancer Progression in an Autocrine Fashion and Predicts Poor Survival in Gastric Cancer.
Lymphoma, B-Cell
Huaier aqueous extract induces apoptosis of human fibrosarcoma HT1080 cells through the mitochondrial pathway.
Lymphoma, B-Cell
Hyperthermia enhances the sensitivity of pancreatic cancer SW1990 cells to gemcitabine through ROS/JNK signaling.
Lymphoma, B-Cell
Ibuprofen Protects from Cypermethrin-Induced Changes in the Striatal Dendritic Length and Spine Density.
Lymphoma, B-Cell
Inhibition of caspase 9 and not caspase 8 mediated apoptosis may determine clinical response to chemotherapy in primary nodal diffuse large B-cell lymphomas.
Lymphoma, B-Cell
Inhibition of Myosin Light-Chain Kinase Enhances the Clearance of Lipopolysaccharide-Induced Lung Inflammation Possibly by Accelerating Neutrophil Apoptosis.
Lymphoma, B-Cell
Inhibition of Proliferation in U937 Cells Treated by Blue Light Irradiation and Combined Blue Light Irradiation/Drug.
Lymphoma, B-Cell
Inhibition of the intrinsic apoptosis pathway downstream of caspase-9 activation causes chemotherapy resistance in diffuse large B-cell lymphoma.
Lymphoma, B-Cell
Inulin Induces Dendritic Cells Apoptosis through the Caspase-Dependent Pathway and Mitochondrial Dysfunction.
Lymphoma, B-Cell
Ketamine induces apoptosis via the mitochondrial pathway in human lymphocytes and neuronal cells.
Lymphoma, B-Cell
Lidocaine induces apoptosis via the mitochondrial pathway independently of death receptor signaling.
Lymphoma, B-Cell
Low temperature exerts protective effects by inhibiting mitochondria-mediated apoptosis pathway following pressure injury to rat muscle.
Lymphoma, B-Cell
Luteolin induces apoptosis in vitro through suppressing the MAPK and PI3K signaling pathways in gastric cancer.
Lymphoma, B-Cell
Methyl Sartortuoate Inhibits Colon Cancer Cell Growth by Inducing Apoptosis and G2/M-Phase Arrest.
Lymphoma, B-Cell
MicroRNA-181a suppresses norethisterone-promoted tumorigenesis of breast epithelial MCF10A cells through the PGRMC1/EGFR-PI3K/Akt/mTOR signaling pathway.
Lymphoma, B-Cell
MiR-145-5p promotes myocardial cell apoptosis in rats with myocardial infarction through PI3K/Akt signaling pathway.
Lymphoma, B-Cell
Mitochondrial separation protein inhibitor inhibits cell apoptosis in rat lungs during intermittent hypoxia.
Lymphoma, B-Cell
Modulation of the DNA repair system and ATR-p53 mediated apoptosis is relevant for tributyltin-induced genotoxic effects in human hepatoma G2 cells.
Lymphoma, B-Cell
Neuroprotective and antioxidant activities of bamboo salt soy sauce against H2O2-induced oxidative stress in rat cortical neurons.
Lymphoma, B-Cell
Non-esterified Fatty Acid Induce Dairy Cow Hepatocytes Apoptosis via the Mitochondria-Mediated ROS-JNK/ERK Signaling Pathway.
Lymphoma, B-Cell
Oral treatment with herbal formula B307 alleviates cardiac failure in aging R6/2 mice with Huntington's disease via suppressing oxidative stress, inflammation, and apoptosis.
Lymphoma, B-Cell
Oral treatment with the herbal formula B307 alleviates cardiac toxicity in doxorubicin-treated mice via suppressing oxidative stress, inflammation, and apoptosis.
Lymphoma, B-Cell
Ozone induces BEL7402 cell apoptosis by increasing reactive oxygen species production and activating JNK.
Lymphoma, B-Cell
Palmitic Acid-Induced Podocyte Apoptosis via the Reactive Oxygen Species-Dependent Mitochondrial Pathway.
Lymphoma, B-Cell
Peroxiredoxin V Silencing Elevates Susceptibility to Doxorubicin-induced Cell Apoptosis via ROS-dependent Mitochondrial Dysfunction in AGS Gastric Cancer Cells.
Lymphoma, B-Cell
Photoactivation of hypericin decreases the viability of RINm5F insulinoma cells through reduction in JNK/ERK phosphorylation and elevation of caspase-9/caspase-3 cleavage and Bax-to-Bcl-2 ratio.
Lymphoma, B-Cell
Photodynamic Effects of Vitamin K3 on Cervical Carcinoma Cells Activating Mitochondrial Apoptosis Pathways.
Lymphoma, B-Cell
Preparation of catechin extracts and nanoemulsions from green tea leaf waste and their inhibition effect on prostate cancer cell PC-3.
Lymphoma, B-Cell
Pro-apoptotic and anti-proliferative effects of corn silk extract on human colon cancer cell lines.
Lymphoma, B-Cell
Protective effects elicited by levosimendan against liver ischemia/reperfusion injury in anesthetized rats.
Lymphoma, B-Cell
Qilin pills alleviate oligoasthenospermia by inhibiting Bax-caspase-9 apoptosis pathway in the testes of model rats.
Lymphoma, B-Cell
Resveratrol inhibits the proliferation of human melanoma cells by inducing G1/S cell cycle arrest and apoptosis.
Lymphoma, B-Cell
Role of Exogenous Hsp72 on Liver Dysfunction during Sepsis.
Lymphoma, B-Cell
Ruanjian Sanjie decoction exhibits antitumor activity by inducing cell apoptosis in breast cancer.
Lymphoma, B-Cell
Shenfu injection prevents sepsis-induced myocardial injury by inhibiting mitochondrial apoptosis.
Lymphoma, B-Cell
Shikonin Exerts Cytotoxic Effects in Human Colon Cancers by Inducing Apoptotic Cell Death via the Endoplasmic Reticulum and Mitochondria-Mediated Pathways.
Lymphoma, B-Cell
Shikonin inhibits TNF-?-induced growth and invasion of rat aortic vascular smooth muscle cells.
Lymphoma, B-Cell
Silencing of human phosphatidylethanolamine-binding protein 4 enhances rituximab-induced death and chemosensitization in B-cell lymphoma.
Lymphoma, B-Cell
Sinoporphyrin Sodium-Mediated Sonodynamic Therapy Inhibits RIP3 Expression and Induces Apoptosis in the H446 Small Cell Lung Cancer Cell Line.
Lymphoma, B-Cell
Small-molecule XIAP antagonist restores caspase-9 mediated apoptosis in XIAP-positive diffuse large B-cell lymphoma cells.
Lymphoma, B-Cell
Subretinal Fluid Levels of Signal-Transduction Proteins and Apoptosis Molecules in Macula-Off Retinal Detachment Undergoing Scleral Buckle Surgery.
Lymphoma, B-Cell
Sulforaphane-induced apoptosis in Xuanwei lung adenocarcinoma cell line XWLC-05.
Lymphoma, B-Cell
Synergistic Effect of Forbesione From Garcinia hanburyi in Combination with 5-Fluorouracil on Cholangiocarcinoma
Lymphoma, B-Cell
Tau phosphorylation and cochlear apoptosis cause hearing loss in 3×Tg-AD Mouse Model of Alzheimer's Disease.
Lymphoma, B-Cell
The cardioprotective effects of diallyl trisulfide on diabetic rats with ex vivo induced ischemia/reperfusion injury.
Lymphoma, B-Cell
The Effect of Bornyl cis-4-Hydroxycinnamate on Melanoma Cell Apoptosis Is Associated with Mitochondrial Dysfunction and Endoplasmic Reticulum Stress.
Lymphoma, B-Cell
The Inhibition Effect of the Seaweed Polyphenol, 7-Phloro-Eckol from Ecklonia Cava on Alcohol-Induced Oxidative Stress in HepG2/CYP2E1 Cells.
Lymphoma, B-Cell
The Protective Role of Selenium Against AFB1-Induced Liver Apoptosis by Death Receptor Pathway in Broilers.
Lymphoma, B-Cell
Thymoquinone from Nigella sativa Seeds Promotes the Antitumor Activity of Noncytotoxic Doses of Topotecan in Human Colorectal Cancer Cells in Vitro.
Lymphoma, B-Cell
Tissue Inhibitor of Metalloproteinase-3 (TIMP-3) induces FAS dependent apoptosis in human vascular smooth muscle cells.
Lymphoma, B-Cell
Trace Mineral Overload Induced Hepatic Oxidative Damage and Apoptosis in Pigs with Long-Term High-Level Dietary Mineral Exposure.
Lymphoma, B-Cell
Uncovering the Anticancer Mechanism of Compound Sophorae Decoction against Ulcerative Colitis-Related Colorectal Cancer in Mice.
Lymphoma, B-Cell
Upregulation of let-7f-5p promotes chemotherapeutic resistance in colorectal cancer by directly repressing several pro-apoptotic proteins.
Lymphoma, B-Cell
Xanthohumol inhibits proliferation of laryngeal squamous cell carcinoma.
Lymphoma, B-Cell
[Celastrol inhibits growth and increases apoptosis of human lung cancer A549 cells].
Lymphoma, B-Cell
[Chronic venous disease increases placental villous angiogenesis and lymphangiogenesis and villous cell apoptosis].
Lymphoma, Follicular
Feedback regulation of mitochondria by caspase-9 in the B cell receptor-mediated apoptosis.
Lymphoma, Follicular
Genetic variants in caspase genes and susceptibility to non-Hodgkin lymphoma.
Lymphoma, Follicular
The involvement of mitochondria and the caspase-9 activation pathway in rituximab-induced apoptosis in FL cells.
Lymphoma, Follicular
The prevention of spontaneous apoptosis of follicular lymphoma B cells by a follicular dendritic cell line: involvement of caspase-3, caspase-8 and c-FLIP.
Lymphoma, Large B-Cell, Diffuse
Inhibition of the intrinsic apoptosis pathway downstream of caspase-9 activation causes chemotherapy resistance in diffuse large B-cell lymphoma.
Lymphoma, Large B-Cell, Diffuse
Small-molecule XIAP antagonist restores caspase-9 mediated apoptosis in XIAP-positive diffuse large B-cell lymphoma cells.
Lymphoma, Mantle-Cell
The heat shock protein 90 inhibitor 17-AAG induces cell cycle arrest and apoptosis in mantle cell lymphoma cell lines by depleting cyclin D1, Akt, Bid and activating caspase 9.
Lymphoma, Non-Hodgkin
Genetic variants in caspase genes and susceptibility to non-Hodgkin lymphoma.
Lymphoma, T-Cell
MicroRNA-based recombinant AAV vector assembly improves efficiency of suicide gene transfer in a murine model of lymphoma.
Lymphoma, T-Cell
Sialic acids linked to glycoconjugates of Fas regulate the caspase-9-dependent and mitochondria-mediated pathway of Fas-induced apoptosis in Jurkat T cell lymphoma.
Malaria
Malarial infection develops mitochondrial pathology and mitochondrial oxidative stress to promote hepatocyte apoptosis.
Malnutrition
Effects of dietary protein and calcium on thymus apoptosis induced by fluoride in female rats (Wistar rats).
Malocclusion
TNF Accelerates Death of Mandibular Condyle Chondrocytes in Rats with Biomechanical Stimulation-Induced Temporomandibular Joint Disease.
Massive Hepatic Necrosis
Intrahepatic activation of caspases in human fulminant hepatic failure.
Mastocytoma
Activation of histidine decarboxylase through post-translational cleavage by caspase-9 in a mouse mastocytoma P-815.
Mastocytoma
Stobadine inhibits doxorubicin-induced apoptosis through a caspase-9 dependent pathway in P815 mastocytoma cells.
Medulloblastoma
Effects of matrine on the proliferation and apoptosis of human medulloblastoma cell line D341.
Medulloblastoma
Fenretinide (4-HPR) Targets Caspase-9, ERK 1/2 and the Wnt3a/?-Catenin Pathway in Medulloblastoma Cells and Medulloblastoma Cell Spheroids.
Medulloblastoma
The alkylphospholipid perifosine induces apoptosis and p21-mediated cell cycle arrest in medulloblastoma.
Medulloblastoma
[Effect of matrine on cell apoptosis and proliferation and the apoptosis related proteins of human medulloblastoma D341 cells in vitro].
Melanoma
A novel dynamic matrix detachment model reveals a shift from apoptosis to necrosis in melanoma cells.
Melanoma
A Novel Oral Astaxanthin Nanoemulsion from Haematococcus pluvialis Induces Apoptosis in Lung Metastatic Melanoma.
Melanoma
Activation of ERK1/2 protects melanoma cells from TRAIL-induced apoptosis by inhibiting Smac/DIABLO release from mitochondria.
Melanoma
Aggressive childhood neuroblastomas do not express caspase-8: an important component of programmed cell death.
Melanoma
Anticancer effects of Daidzein against the human melanoma cell lines involves cell cycle arrest, autophagy and deactivation of PI3K/AKT signalling pathways.
Melanoma
Antineoplastic Effects and Mechanisms of a New RGD Chimeric Peptide from Bullfrog Skin on the Proliferation and Apoptosis of B16F10 Cells.
Melanoma
Antiproliferation of melanoma cells by polysaccharide isolated from Zizyphus jujuba.
Melanoma
Apoptosis protease activator protein-1 expression is dispensable for response of human melanoma cells to distinct proapoptotic agents.
Melanoma
Bcl-2 family proteins and cytoskeleton changes involved in DM-1 cytotoxic effect on melanoma cells.
Melanoma
Biphenylalkylacetylhydroquinone ethers suppress the proliferation of murine B16 melanoma cells.
Melanoma
Caspase-9 and Apaf-1 are expressed and functionally active in human neuroblastoma tumor cell lines with 1p36 LOH and amplified MYCN.
Melanoma
Chrysin induces cell apoptosis in human uveal melanoma cells via intrinsic apoptosis.
Melanoma
Cisplatin-induced apoptosis in melanoma cells: role of caspase-3 and caspase-7 in Apaf-1 proteolytic cleavage and in execution of the degradative phases.
Melanoma
Curcumin induces cell death in human uveal melanoma cells through mitochondrial pathway.
Melanoma
Diallyl disulfide induces caspase-dependent apoptosis via mitochondria-mediated intrinsic pathway in B16F-10 melanoma cells by up-regulating p53, caspase-3 and down-regulating pro-inflammatory cytokines and nuclear factor-??-mediated Bcl-2 activation.
Melanoma
Down-regulation of mcl-1 by small interfering RNA sensitizes resistant melanoma cells to fas-mediated apoptosis.
Melanoma
Flavonoids in Ginkgo biloba fallen leaves induce apoptosis through modulation of p53 activation in melanoma cells.
Melanoma
HDAC-inhibitor (S)-8 disrupts HDAC6-PP1 complex prompting A375 melanoma cell growth arrest and apoptosis.
Melanoma
IFN-beta pretreatment sensitizes human melanoma cells to TRAIL/Apo2 ligand-induced apoptosis.
Melanoma
IL-24 gene transfer sensitizes melanoma cells to erlotinib through modulation of the Apaf-1 and Akt signaling pathways.
Melanoma
Inactivation of the apoptosis effector Apaf-1 in malignant melanoma.
Melanoma
Inhibition of fatty acid synthase in melanoma cells activates the intrinsic pathway of apoptosis.
Melanoma
Inhibition of melanoma growth and metastasis by ATF2-derived peptides.
Melanoma
Inhibitory activity of acteoside in melanoma via regulation of the ER?-Ras/Raf1-STAT3 pathway.
Melanoma
Inverse Association Between Antiviral Immunity and Lupus Disease Activity.
Melanoma
Livin/melanoma inhibitor of apoptosis protein as a potential therapeutic target for the treatment of malignancy.
Melanoma
Markers of mitochondrial dysfunction during the diclofenac-induced apoptosis in melanoma cell lines.
Melanoma
MicroRNA-365 promotes apoptosis in human melanoma cell A375 treated with hydatid cyst fluid of Echinococcus granulosus sensu stricto.
Melanoma
Molecular, Biological and Structural Features of VL CDR-1 Rb44 Peptide, Which Targets the Microtubule Network in Melanoma Cells.
Melanoma
Norcantharidin induces human melanoma A375-S2 cell apoptosis through mitochondrial and caspase pathways.
Melanoma
P53 apoptosis mediator PERP: localization, function and caspase activation in uveal melanoma.
Melanoma
PRIMA-1Met/APR-246 induces wild-type p53-dependent suppression of malignant melanoma tumor growth in 3D culture and in vivo.
Melanoma
Resveratrol inhibits the proliferation of human melanoma cells by inducing G1/S cell cycle arrest and apoptosis.
Melanoma
Targeting TGF-?-Mediated SMAD Signaling Pathway via Novel Recombinant Cytotoxin II: A Potent Protein from Naja naja oxiana Venom in Melanoma.
Melanoma
The antidepressant sertraline downregulates Akt and has activity against melanoma cells.
Melanoma
The Antitumor Activity of Antrodia camphorata in Melanoma Cells: Modulation of Wnt/?-Catenin Signaling Pathways.
Melanoma
The gallium complex KP46 exerts strong activity against primary explanted melanoma cells and induces apoptosis in melanoma cell lines.
Melanoma
TNF-related apoptosis-inducing ligand-induced apoptosis of melanoma is associated with changes in mitochondrial membrane potential and perinuclear clustering of mitochondria.
Melanoma
Topical 2'-Hydroxyflavanone for Cutaneous Melanoma.
Melanoma
Vernolide-A, a sesquiterpene lactone from Vernonia cinerea, induces apoptosis in B16F-10 melanoma cells by modulating p53 and caspase-3 gene expressions and regulating NF-?B-mediated bcl-2 activation.
Melanoma
Vinblastine-induced apoptosis of melanoma cells is mediated by Ras homologous A protein (Rho A) via mitochondrial and non-mitochondrial-dependent mechanisms.
Memory Disorders
Caspase-9 mediates synaptic plasticity and memory deficits of Danish dementia knock-in mice: caspase-9 inhibition provides therapeutic protection.
Memory Disorders
Puerarin attenuates amyloid-beta-induced cognitive impairment through suppression of apoptosis in rat hippocampus in vivo.
Meningioma
Role of Caspase-9 Gene Ex5+32 G>A (rs1052576) Variant in Susceptibility to Primary Brain Tumors.
Meningitis
Neuroinflammation trajectories precede cognitive impairment after experimental meningitis-evidence from an in vivo PET study.
Mesothelioma
Effects of cisplatin and panobinostat on human mesothelial (Met-5A) and malignant pleural mesothelioma (MSTO-211H) cells.
Mesothelioma
Mitochondria determine the efficacy of anti-cancer agents that interact with DNA but not the cytoskeleton.
Mesothelioma
The Construction and Analysis of ceRNA Network and Patterns of Immune Infiltration in Mesothelioma With Bone Metastasis.
Mesothelioma, Malignant
Quercetin and Cisplatin combined treatment altered cell cycle and mitogen activated protein kinase expressions in malignant mesotelioma cells.
Mouth Neoplasms
Anticancer Activity of Apaziquone in Oral Cancer Cells and Xenograft Model: Implications for Oral Cancer Therapy.
Mouth Neoplasms
Apoptotic effects of dehydrocrenatidine via JNK and ERK pathway regulation in oral squamous cell carcinoma.
Mouth Neoplasms
Celecoxib derivatives induce apoptosis via the disruption of mitochondrial membrane potential and activation of caspase 9.
Mouth Neoplasms
Design and characterization of a novel Arthrospira platensis glutathione oxido-reductase-derived antioxidant peptide GM15 and its potent anti-cancer activity via caspase-9 mediated apoptosis in oral cancer cells.
Mouth Neoplasms
MicroRNA-205 suppresses the oral carcinoma oncogenic activity via down-regulation of Axin-2 in KB human oral cancer cell.
Mouth Neoplasms
NGAL is Downregulated in Oral Squamous Cell Carcinoma and Leads to Increased Survival, Proliferation, Migration and Chemoresistance.
Multiple Myeloma
Alantolactone induces G1 phase arrest and apoptosis of multiple myeloma cells and overcomes bortezomib resistance.
Multiple Myeloma
Apaf-1/cytochrome c-independent and Smac-dependent induction of apoptosis in multiple myeloma (MM) cells.
Multiple Myeloma
Caspase polymorphisms and genetic susceptibility to multiple myeloma.
Multiple Myeloma
Caspase-2 functions upstream of mitochondria in endoplasmic reticulum stress-induced apoptosis by bortezomib in human myeloma cells.
Multiple Myeloma
Decursin and Doxorubicin Are in Synergy for the Induction of Apoptosis via STAT3 and/or mTOR Pathways in Human Multiple Myeloma Cells.
Multiple Myeloma
Genetic variation in cell cycle and apoptosis related genes and multiple myeloma risk.
Multiple Myeloma
TP53 Regulated Inhibitor Of Apoptosis 1 (TRIAP1) stable silencing Increases late apoptosis by Upregulation of caspase 9 and APAF1 in RPMI8226 multiple myeloma cell line.
Multiple Sclerosis
CASP-9: A susceptibility locus for multiple sclerosis in Italy.
Multiple System Atrophy
Activated caspase-9 immunoreactivity in glial and neuronal cytoplasmic inclusions in multiple system atrophy.
Muscular Atrophy
Herbal complex 'Buyang Huanwu Tang' improves motor endplate function of denervated-dependent skeletal muscle atrophy in rat.
Muscular Atrophy
Role of caspase-9 in the effector caspases and genome expressions, and growth of bovine skeletal myoblasts.
Muscular Atrophy
Targeted suppression of ?-calpain and caspase 9 expression and its effect on caspase 3 and caspase 7 in satellite cells of Korean Hanwoo cattle.
Muscular Diseases
Apoptosis of skeletal muscle on steroid-induced myopathy in rats.
Myocardial Infarction
Butorphanol attenuates myocardial ischemia reperfusion injury through inhibiting mitochondria-mediated apoptosis in mice.
Myocardial Infarction
Calcium-sensing receptor-mediated mitogen-activated protein kinase pathway improves the status of transplanted mouse embryonic stem cells in rats with acute myocardial infarction.
Myocardial Infarction
Dexmedetomidine alleviates cardiomyocyte apoptosis and cardiac dysfunction may be associated with inhibition of RhoA/ROCK pathway in mice with myocardial infarction.
Myocardial Infarction
Mediation of exogenous hydrogen sulfide in recovery of ischemic post-conditioning-induced cardioprotection via down-regulating oxidative stress and up-regulating PI3K/Akt/GSK-3? pathway in isolated aging rat hearts.
Myocardial Infarction
MiR-808 inhibits cardiomyocyte apoptosis and expressions of caspase-3 and caspase-9 in rats with myocardial infarction by regulating TGF-?1 signaling pathway.
Myocardial Infarction
[Activation of JAK2/STAT3 pathway by CPU0213 alleviates myocardial ischemia-reperfusion and oxidative stress injury in rats].
Myocardial Ischemia
Proinflammatory phenotype of coronary arteries promotes endothelial apoptosis in aging.
Myocardial Ischemia
[The effects of salidroside on the apoptosis pathway of myocardial cells in acute exhausted rats].
Myocarditis
Enterovirus-related activation of the cardiomyocyte mitochondrial apoptotic pathway in patients with acute myocarditis.
Nasopharyngeal Carcinoma
Indole-3-carbinol inhibits nasopharyngeal carcinoma.
Nasopharyngeal Carcinoma
Isoliquiritigenin suppresses the proliferation and induced apoptosis via miR-32/LATS2/Wnt in nasopharyngeal carcinoma.
Nasopharyngeal Carcinoma
Junduqing extractive promotes the apoptosis of nasopharyngeal carcinoma cells through down-regulating Mcl-1 and Bcl-xL and up-regulating Caspase-3, Caspase-8 and Caspase-9.
Nasopharyngeal Carcinoma
Phosphatidylinositol 3-kinase inhibitor(LY294002) induces apoptosis of human nasopharyngeal carcinoma in vitro and in vivo.
Nasopharyngeal Carcinoma
[The inhibited effect of matrine on human nasopharyngeal carcinoma CNE2 cells and the expression of apoptosis related gene Caspase in vitro].
Neoplasm Metastasis
Alzheimer's drug Memantine inhibits metastasis and p-Erk protein expression on 4T1 breast cancer cells.
Neoplasm Metastasis
Carnitine palmitoyl transferase-1A (CPT1A): a new tumor specific target in human breast cancer.
Neoplasm Metastasis
Curcumol inhibits lung adenocarcinoma growth and metastasis via inactivation of PI3K/AKT and Wnt/ß-catenin pathway.
Neoplasm Metastasis
EMP1 regulates caspase-9 and VEGFC expression and suppresses prostate cancer cell proliferation and invasion.
Neoplasm Metastasis
EMP1, a member of a new family of antiproliferative genes in breast carcinoma.
Neoplasm Metastasis
Fenton-reaction-stimulative nanoparticles decorated with a reactive-oxygen-species (ROS)-responsive molecular switch for ROS amplification and triple negative breast cancer therapy.
Neoplasm Metastasis
Fructooligosaccharides and wheat bran fed at similar fermentation levels differentially affect the expression of genes involved in transport, signaling, apoptosis, cell proliferation, and oncogenesis in the colon epithelia of healthy Fischer 344 rats.
Neoplasm Metastasis
Influence of caspases 8 and 9 gene promoter polymorphism on prostate cancer susceptibility and early development of hormone refractory prostate cancer.
Neoplasm Metastasis
In vivo and in vitro inhibition of human gastric cancer progress by upregulating Kank1 gene.
Neoplasm Metastasis
Protein expression differences between lung adenocarcinoma and squamous cell carcinoma with brain metastasis.
Neoplasm Metastasis
Suppressing effects of daily oral supplementation of beta-glucan extracted from Agaricus blazei Murill on spontaneous and peritoneal disseminated metastasis in mouse model.
Neoplasm Metastasis
The Construction and Analysis of ceRNA Network and Patterns of Immune Infiltration in Mesothelioma With Bone Metastasis.
Neoplasm Metastasis
[A study on the expression of CASP9 gene and its polymorphism distribution in non-small cell lung cancer]
Neoplasm Metastasis
[Expressions and clinical significances of iASPP and caspase-9 in esophageal cancer].
Neoplasms
125I seeds irradiation inhibits tumor growth and induces apoptosis by Ki-67, P21, survivin, livin and caspase-9 expression in lung carcinoma xenografts.
Neoplasms
3-m-bromoacetylamino benzoic acid ethyl ester: a new cancericidal agent that activates the apoptotic pathway through caspase-9.
Neoplasms
9-cis retinoic acid inhibits cumulus cell apoptosis during the maturation of bovine cumulus-oocyte-complexes.
Neoplasms
?-Hydroxybutyrate exacerbates lipopolysaccharide/ d-galactosamine-induced inflammatory response and hepatocyte apoptosis in mice.
Neoplasms
?-Tocotrienol treatment is more effective against hypoxic tumor cells than normoxic cells: potential implications for cancer therapy.
Neoplasms
A caspase-9 variant missing the catalytic site is an endogenous inhibitor of apoptosis.
Neoplasms
A Human Fetal Prostate Xenograft Model of Developmental Estrogenization.
Neoplasms
A meta-analysis of caspase 9 polymorphisms in promoter and exon sequence on cancer susceptibility.
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A methoxyflavanone derivative from the Asian medicinal herb (Perilla frutescens) induces p53-mediated G2/M cell cycle arrest and apoptosis in A549 human lung adenocarcinoma.
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A modified thymosin alpha 1 inhibits the growth of breast cancer both in vitro and in vivo: suppressment of cell proliferation, inducible cell apoptosis and enhancement of targeted anticancer effects.
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A novel thiazolidine compound induces caspase-9 dependent apoptosis in cancer cells.
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A plant-based medicinal food inhibits the growth of human gastric carcinoma by reversing epithelial-mesenchymal transition via the canonical Wnt/?-catenin signaling pathway.
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A polysaccharide from Trametes robiniophila inhibits human osteosarcoma xenograft tumor growth in vivo.
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A protective effect after clearance of orthotopic rat hepatocellular carcinoma by nanosecond pulsed electric fields.
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ABT-263 induces G1/G0-phase arrest, apoptosis and autophagy in human esophageal cancer cells in vitro.
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Activation of caspase-9 with irradiation inhibits invasion and angiogenesis in SNB19 human glioma cells.
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Activation of P2X(7)-mediated apoptosis Inhibits DMBA/TPA-induced formation of skin papillomas and cancer in mice.
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Adenovirus encoding HIV-1 Vpr activates caspase 9 and induces apoptotic cell death in both p53 positive and negative human tumor cell lines.
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Adenovirus-mediated p53 and ING4 gene co?transfer elicits synergistic antitumor effects through enhancement of p53 acetylation in breast cancer.
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Aggressive childhood neuroblastomas do not express caspase-8: an important component of programmed cell death.
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Airborne fine particulate matter induces multiple cell death pathways in human lung epithelial cells.
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Alantolactone induces cell apoptosis partially through down-regulation of testes-specific protease 50 expression.
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Alkylamino Phenol Derivative Induces Apoptosis by Inhibiting EGFR Signaling Pathway in Breast Cancer Cells.
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Aloe-emodin (AE) nanoparticles suppresses proliferation and induces apoptosis in human lung squamous carcinoma via ROS generation in vitro and in vivo.
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Ameliorative effect of taurine-chloramine in azathioprine-induced testicular damage; a deeper insight into the mechanism of protection.
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An active molecule from Pulsatilla chinensis, Pulsatilla saponin A, induces apoptosis and inhibits tumor growth of human colon cancer cells without or with 5-FU.
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An in vivo anti-tumor effect of eckol from marine brown algae by improving the immune response.
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An investigation of the immunotoxicity of oil sands processed water and leachates in trout leukocytes.
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Analyses of apoptotic regulators CASP9 and DFFA at 1P36.2, reveal rare allele variants in human neuroblastoma tumours.
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Analysis of caspase activities in rat mammary tumours induced by N-methyl-nitrosourea.
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Analysis of Serum Markers with Regard to Treatment Procedures in Advanced Stage Prostate Cancer Patients.
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Annulus cells from more degenerated human discs show modified gene expression in 3D culture compared with expression in cells from healthier discs.
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Antagonizing XIAP-mediated caspase-3 inhibition. Achilles' heel of cancers?
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Anti-apoptotic and pro-survival effect of exercise training on early aged hypertensive rat cerebral cortex.
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Anti-apoptotic and pro-survival effects of exercise training on hypertensive hearts.
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Anti-cancer activities of metal-based complexes by regulating the VEGF/VEGFR2 signaling pathway and apoptosis-related factors Bcl-2, Bax, and caspase-9 to inhibit angiogenesis and induce apoptosis.
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Anti-cancer effect of tectochrysin in NSCLC cells through overexpression of death receptor and inactivation of STAT3.
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Anti-Condyloma acuminata mechanism of microRNAs-375 modulates HPV in cervical cancer cells via the UBE3A and IGF-1R pathway.
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Anti-Inflammatory and Apoptotic Signaling Effect of Fucoxanthin on Benzo(A)Pyrene-Induced Lung Cancer in Mice.
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Anti-inflammatory Role of Mesenchymal Stem Cells in an Acute Lung Injury Mouse Model.
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Anti-tumor effects of atractylenolide I isolated from Atractylodes macrocephala in human lung carcinoma cell lines.
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Antiapoptotic and mitochondrial biogenetic effects of exercise training on ovariectomized hypertensive rat hearts.
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Antiapoptotic effect of exercise training on ovariectomized rat hearts.
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Antiapoptotic effects of estrogen in normal and cancer human cervical epithelial cells.
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Antibodies against Clonorchis sinensis LDH could cross-react with LDHB localizing on the plasma membrane of human hepatocarcinoma cell SMMC-7721 and induce apoptosis.
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Anticancer drug 2-methoxyestradiol protects against renal ischemia/reperfusion injury by reducing inflammatory cytokines expression.
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Anticancer effects induced by artichoke extract in oral squamous carcinoma cell lines.
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Anticancer Effects of Herbal Medicine Compounds and Novel Formulations: a Literature Review.
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Antiinflammatory properties of IL-10 rescue small-for-size liver grafts.
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Antioxidant-modulated cytotoxicity of silver nanoparticles.
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Antiproliferative activity and apoptosis-inducing mechanism of constituents from Toona sinensis on human cancer cells.
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Antiproliferative and Apoptotic Effects of Shemamruthaa, a Herbal Preparation, in 7,12-Dimethylbenz(a)Anthracene-Induced Breast Cancer Rats.
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Antitumor activity of ginsenoside Rd in gastric cancer via up-regulation of Caspase-3 and Caspase-9.
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Apaf-1 and caspase-9 accelerate apoptosis, but do not determine whether factor-deprived or drug-treated cells die.
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Apaf-1 and caspase-9 do not act as tumor suppressors in myc-induced lymphomagenesis or mouse embryo fibroblast transformation.
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Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition.
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Apollon modulates chemosensitivity in human esophageal squamous cell carcinoma.
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Apoptosis and autophagy: Regulation of caspase-9 by phosphorylation.
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Apoptosis and heart failure: mechanisms and therapeutic implications.
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Apoptosis inducing effects of Kuding tea polyphenols in human buccal squamous cell carcinoma cell line BcaCD885.
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Apoptosis induction effect of Apocynum venetum polyphenol on human U87 glioma cells via NF-?B pathway.
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Apoptosis induction in renal cell carcinoma by TRAIL and gamma-radiation is impaired by deficient caspase-9 cleavage.
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Apoptosis protease activator protein-1 expression is dispensable for response of human melanoma cells to distinct proapoptotic agents.
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Apoptosis: A biomarker of high-risk phenotype in pediatric acute myeloid leukemia?
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Apoptosome-independent activation of the lysosomal cell death pathway by caspase-9.
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Apple procyanidins induce tumor cell apoptosis through mitochondrial pathway activation of caspase-3.
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Arsenic Alters Exosome Quantity and Cargo to Mediate Stem Cell Recruitment Into a Cancer Stem Cell-Like Phenotype.
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Asiatic acid induces colon cancer cell growth inhibition and apoptosis through mitochondrial death cascade.
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Association of soluble apoptotic markers with impaired left ventricular deformation in patients with rheumatoid arthritis. Effects of inhibition of interleukin-1 activity by anakinra.
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Attenuation effect of polydeoxyribonucleotide on inflammatory cytokines and apoptotic factors induced by particulate matter (PM10) damage in human bronchial cells.
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Attenuation of Aluminum Chloride-Induced Neuroinflammation and Caspase Activation Through the AKT/GSK-3? Pathway by Hesperidin in Wistar Rats.
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Author Correction: Relationship Between CASP9 and CASP10 Gene Polymorphisms and Cancer Susceptibility: Evidence from an Updated Meta-analysis.
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Author Correction: Tumor cells suppress radiation-induced immunity by hijacking caspase 9 signaling.
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Autocrine motility factor signaling induces tumor apoptotic resistance by regulations Apaf-1 and Caspase-9 apoptosome expression.
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Autophagy in the physiological endometrium and cancer.
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Autophagy Induced by Tumor Necrosis Factor ? Mediates Intrinsic Apoptosis in Trophoblastic Cells.
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Avasimibe exerts anticancer effects on human glioblastoma cells via inducing cell apoptosis and cell cycle arrest.
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Azoxystrobin Induces Apoptosis of Human Esophageal Squamous Cell Carcinoma KYSE-150 Cells through Triggering of the Mitochondrial Pathway.
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Bamboo salt has in vitro anticancer activity in HCT-116 cells and exerts anti-metastatic effects in vivo.
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Bax translocation mediated mitochondrial apoptosis and caspase dependent photosensitizing effect of Ficus religiosa on cancer cells.
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Benzo(a)pyrene-coated onto Fe2O3 particles-induced apoptotic events in the lungs of Sprague-Dawley rats.
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Benzophenone semicarbazone protection strategy for synthesis of aza-glycine containing aza-peptides.
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Benzo[f]indole-4,9-dione Derivatives Effectively Inhibit the Growth of Triple-Negative Breast Cancer.
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Beraprost sodium preconditioning prevents inflammation, apoptosis, and autophagy during hepatic ischemia-reperfusion injury in mice via the P38 and JNK pathways.
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Berbamine inhibited the growth of prostate cancer cells in vivo and in vitro via triggering intrinsic pathway of apoptosis.
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Berberine activates caspase-9/cytochrome c-mediated apoptosis to suppress triple-negative breast cancer cells in vitro and in vivo.
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Berberine promotes antiproliferative effects of epirubicin in T24 bladder cancer cells by enhancing apoptosis and cell cycle arrest?.
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Bicarbonate transport inhibitor SITS modulates pH homeostasis triggering apoptosis of Dalton's lymphoma: implication of novel molecular mechanisms.
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Bifidobacterium infantis-mediated HSV-TK/GCV suicide gene therapy induces both extrinsic and intrinsic apoptosis in a rat model of bladder cancer.
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Biological characterization of bovine mammary epithelial cell lines immortalized by HPV16 E6/E7 and SV40T.
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Biological Potential and Mechanism of Prodigiosin from Serratia marcescens Subsp. lawsoniana in Human Choriocarcinoma and Prostate Cancer Cell Lines.
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Boeravinone B alleviates gut dysbiosis during myocardial infarction-induced cardiotoxicity in rats.
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Bortezomib sensitizes non-small cell lung cancer to mesenchymal stromal cell-delivered inducible caspase-9-mediated cytotoxicity.
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Bromelain-Induced Apoptosis in GI-101A Breast Cancer Cells.
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C1q/tumor necrosis factor-related protein-6 attenuates TNF-?-induced apoptosis in salivary acinar cells via AMPK/SIRT1-modulated miR-34a-5p expression.
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C5, A Cassaine Diterpenoid Amine, Induces Apoptosis via the Extrinsic Pathways in Human Lung Cancer Cells and Human Lymphoma Cells.
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Cadmium exposure induces apoptosis, inflammation and immunosuppression through CYPs activation and antioxidant dysfunction in common carp neutrophils.
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Cadmium induced inflammation and apoptosis of porcine epididymis via activating RAF1/MEK/ERK and NF-?B pathways.
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Canavanine augments proapoptotic effects of arginine deprivation in cultured human cancer cells.
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Cancer gene therapy using a survivin mutant adenovirus.
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Cancer gene therapy with iCaspase-9 transcriptionally targeted to tumor endothelial cells.
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Cardiomyocytes undergo apoptosis in human immunodeficiency virus cardiomyopathy through mitochondrion- and death receptor-controlled pathways.
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CASP-9 gene functional polymorphisms and cancer risk: A large-scale association study plus meta-analysis.
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Caspase 8 and caspase 9 gene polymorphisms and susceptibility to gastric cancer.
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Caspase 9 promoter polymorphisms and risk of primary lung cancer.
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Caspase polymorphisms and prognosis of hepatocellular carcinoma.
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Caspase-2-induced apoptosis is dependent on caspase-9, but its processing during UV- or tumor necrosis factor-dependent cell death requires caspase-3.
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Caspase-8 and caspase-7 sequentially mediate proteolytic activation of acid sphingomyelinase in TNF-R1 receptosomes.
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Caspase-9 and Apaf-1 are expressed and functionally active in human neuroblastoma tumor cell lines with 1p36 LOH and amplified MYCN.
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Caspase-9 as a therapeutic target for treating cancer.
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Caspase-9 mediates Puma activation in UCN-01-induced apoptosis.
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Caspase-9: A Multimodal Therapeutic Target With Diverse Cellular Expression in Human Disease.
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Caspase-9: structure, mechanisms and clinical application.
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Cassia tora L. (Jue-ming-zi) has anticancer activity in TCA8113 cells in vitro and exerts anti-metastatic effects in vivo.
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Cationic long-chain ceramide LCL-30 induces cell death by mitochondrial targeting in SW403 cells.
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Central role of Fas-associated death domain protein in apoptosis induction by the mitogen-activated protein kinase kinase inhibitor CI-1040 (PD184352) in acute lymphocytic leukemia cells in vitro.
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Changes in activities of caspase-8 and caspase-9 in human cervical malignancy.
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Changes in Glutathione, Oxidative Stress, Mitochondrial Membrane Potential in Apoptosis Involving the Anticancer Activity Of Cantharidin Isolated From Red-Headed Blister Beetles, Epicauta Hirticornis.
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Characterization and anti-tumor activity of saponin-rich fractions of South Korean sea cucumbers (Apostichopus japonicus).
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Chemotherapy with hybrid liposomes for human breast tumors along with apoptosis in vivo.
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Chlorpyrifos induced oxidative stress to promote apoptosis and autophagy through the regulation of miR-19a-AMPK axis in common carp.
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Citronellol, an Acyclic Monoterpene Induces Mitochondrial-Mediated Apoptosis through Activation of Proapoptotic Factors in MCF-7 and MDA-MB-231 Human Mammary Tumor Cells.
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Cleavage of caspases-1, -3, -6, -8 and -9 substrates by proteases in skeletal muscles from mice undergoing cancer cachexia.
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Cleavage of survivin by Granzyme M triggers degradation of the survivin-XIAP complex to free caspase activity leading to cytolysis of target tumor cells.
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Clinically significant copy number alterations and complex rearrangements of MYB and NFIB in head and neck adenoid cystic carcinoma.
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Co-transduction of Apaf-1 and caspase-9 augments etoposide-induced apoptosis in U-373MG glioma cells.
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Combination of quercetin and cisplatin enhances apoptosis in OSCC cells by downregulating xIAP through the NF-?B pathway.
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Combination of TNF-? and graphene oxide-loaded BEZ235 to enhance apoptosis of PIK3CA mutant colorectal cancer cells.
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Combination therapy with epigenetic-targeted and chemotherapeutic drugs delivered by nanoparticles to enhance the chemotherapy response and overcome resistance by breast cancer stem cells.
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Combinatorial effect of zoledronic acid and irradiation on the prevention of DMBA-induced precancerogenic changes in the mammary tissues of rats.
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Combined effects of Lenvatinib and iodine-131 on cell apoptosis in nasopharyngeal carcinoma through inducing endoplasmic reticulum stress.
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Comparative cytotoxic response of nickel ferrite nanoparticles in human liver HepG2 and breast MFC-7 cancer cells.
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Comparative proteomics analysis of caspase-9-protein complexes in untreated and cytochrome c/dATP stimulated lysates of NSCLC cells.
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Comparisons of the anti-tumor activity of polysaccharides from fermented mycelia and cultivated fruiting bodies of Cordyceps militaris in vitro.
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Copper-induced tight junction mRNA expression changes, apoptosis and antioxidant responses via NF-?B, TOR and Nrf2 signaling molecules in the gills of fish: preventive role of arginine.
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Cordycepin Induced MA-10 Mouse Leydig Tumor Cell Apoptosis through Caspase-9 Pathway.
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Costunolide induces mitochondria-mediated apoptosis in human gastric adenocarcinoma BGC-823 cells.
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CpG island promoter hypermethylation of the pro-apoptotic gene caspase-8 is a common hallmark of relapsed glioblastoma multiforme.
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Cucurbita ficifolia Fruit Extract Induces Tp53/Caspase-Mediated Apoptosis in MCF-7 Breast Cancer Cells.
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Cucurbitacin B induces apoptosis by inhibition of the JAK/STAT pathway and potentiates antiproliferative effects of gemcitabine on pancreatic cancer cells.
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Cucurbitacin E induces apoptosis of human prostate cancer cells via cofilin-1 and mTORC1.
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Curcumol inhibits lung adenocarcinoma growth and metastasis via inactivation of PI3K/AKT and Wnt/ß-catenin pathway.
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CXCL8 gene silencing promotes neuroglial cells activation while inhibiting neuroinflammation through the PI3K/Akt/NF-?B-signaling pathway in mice with ischemic stroke.
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CXCR4-gp120-IIIB interactions induce caspase-mediated apoptosis of prostate cancer cells and inhibit tumor growth.
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Cycloart-24-ene-26-ol-3-one, a New Cycloartane Isolated from Leaves of Aglaia exima Triggers Tumour Necrosis Factor-Receptor 1-Mediated Caspase-Dependent Apoptosis in Colon Cancer Cell Line.
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Cyclophosphamide induces caspase 9-dependent apoptosis in 9L tumor cells.
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Cytotoxic and Antimicrobial Evaluations of Novel Apoptotic and Anti-Angiogenic Spiro Cyclic 2-Oxindole Derivatives of 2-Amino-tetrahydroquinolin-5-one.
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Cytotoxic and antioxidant activity of 4-methylthio-3-butenyl isothiocyanate from Raphanus sativus L. (Kaiware Daikon) sprouts.
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Cytotoxic effects, inflammatory response and apoptosis induction of cyclophosphamide in the peripheral blood leukocyte of blunt snout bream (Megalobrama amblycephala).
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D-Pinitol treatment induced the apoptosis in human leukemia MOLT-4 cells by improved apoptotic signaling pathway.
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Daphnane Diterpenoids from Daphne genkwa Inhibit PI3K/Akt/mTOR Signaling and Induce Cell Cycle Arrest and Apoptosis in Human Colon Cancer Cells.
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Death induction by recombinant native TRAIL and its prevention by a caspase 9 inhibitor in primary human esophageal epithelial cells.
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Debio-0932, a second generation oral Hsp90 inhibitor, induces apoptosis in MCF-7 and MDA-MB-231 cell lines.
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Deguelin targets multiple oncogenic signaling pathways to combat human malignancies.
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Delayed growth of glioma by a polysaccharide from Aster tataricus involve upregulation of Bax/Bcl-2 ratio, activation of caspase-3/8/9, and downregulation of the Akt.
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Delicaflavone induces apoptosis via mitochondrial pathway accompanying G2/M cycle arrest and inhibition of MAPK signaling cascades in cervical cancer HeLa cells.
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Delicaflavone induces ROS-mediated apoptosis and inhibits PI3K/AKT/mTOR and Ras/MEK/Erk signaling pathways in colorectal cancer cells.
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Deltonin, a Steroidal Saponin, Inhibits Colon Cancer Cell Growth in Vitro and Tumor Growth in Vivo via Induction of Apoptosis and Antiangiogenesis.
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Deoxynivalenol induced apoptosis and inflammation of IPEC-J2 cells by promoting ROS production.
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Deoxynivalenol induced mouse skin tumor initiation: Elucidation of molecular mechanisms in human HaCaT keratinocytes.
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Depression of p53-independent Akt survival signals in human oral cancer cells bearing mutated p53 gene after exposure to high-LET radiation.
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Design and Synthesis of Novel Anti-Proliferative Emodin Derivatives and Studies on their Cell Cycle Arrest, Apoptosis Pathway and Migration.
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Design and synthesis of novel azapeptide activators of apoptosis mediated by caspase-9 in cancer cells.
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Design, synthesis and antitumor evaluation of new 1,8-naphthalimide derivatives targeting nuclear DNA.
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Design, synthesis and biological evaluation of cinnamic acyl shikonin derivatives.
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Design, Synthesis and Pharmacological Evaluation of Three Novel Dehydroabietyl Piperazine Dithiocarbamate Ruthenium (II) Polypyridyl Complexes as Potential Antitumor Agents: DNA Damage, Cell Cycle Arrest and Apoptosis Induction.
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Developing a circularly permuted variant of Renilla luciferase as a bioluminescent sensor for measuring Caspase-9 activity in the cell-free and cell-based systems.
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Development and In Vitro Evaluation of 2-Methoxyestradiol Loaded Polymeric Micelles for Enhancing Anticancer Activities in Prostate Cancer.
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Development and optimization of a binding assay for the XIAP BIR3 domain using fluorescence polarization.
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Development of an alternative zebrafish model for drug-induced intestinal toxicity.
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Dietary isothiocyanate iberin inhibits growth and induces apoptosis in human glioblastoma cells.
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Dietary turmeric post-treatment decreases DMBA-induced hamster buccal pouch tumor growth by altering cell proliferation and apoptosis-related markers.
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Differential caspase-9-dependent signaling pathway between tumor necrosis factor receptor- and Fas-mediated hepatocyte apoptosis in mice.
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Diindolylmethane and Lupeol Modulates Apoptosis and Cell Proliferation in N-Butyl-N-(4-Hydroxybutyl) Nitrosamine Initiated and Dimethylarsinic Acid Promoted rat Bladder Carcinogenesis.
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Dioscin attenuates hepatic ischemia-reperfusion injury in rats through inhibition of oxidative-nitrative stress, inflammation and apoptosis.
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Discovery of novel second mitochondria-derived activator of caspase mimetics as selective inhibitor of apoptosis protein inhibitors.
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DK1 Induces Apoptosis via Mitochondria-Dependent Signaling Pathway in Human Colon Carcinoma Cell Lines In Vitro.
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DNA targeting polyaza macrobicyclic dizinc(II) complexes promoting high in vitro caspase dependent anti-proliferative activity against human carcinoma cancer cells.
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DNA-ligase IV and DNA-protein kinase play a critical role in deficient caspases activation in apoptosis-resistant cancer cells by using doxorubicin.
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Dose-dependent protective effect of baicalin against testicular torsion-detorsion in rats.
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Down regulation of caspase-9 is a frequent event in patients with stage II colorectal cancer and correlates with poor clinical outcome.
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Down-regulated expression of OPCML predicts an unfavorable prognosis and promotes disease progression in human gastric cancer.
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Down-regulation of caspase 3 in breast cancer: a possible mechanism for chemoresistance.
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Down-regulation of tyrosine aminotransferase at a frequently deleted region 16q22 contributes to the pathogenesis of hepatocellular carcinoma.
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E2F-1 induces melanoma cell apoptosis via PUMA up-regulation and Bax translocation.
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Effectiveness and Anticancer Activity of a Novel Phenolic Compound from Garcinia porrecta Against the MCF-7 Breast Cancer Cell Line in vitro and in silico.
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Effects of bufalin and cinobufagin on the proliferation of androgen dependent and independent prostate cancer cells.
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Effects of Caspase 9 Gene Polymorphism in Patients with Prostate Cancer.
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Effects of Caspase-9 and Survivin Gene Polymorphisms in Pancreatic Cancer Risk and Tumor Characteristics.
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Effects of dapagliflozin in experimental sepsis model in rats.
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Effects of early administration of insulin-like growth factor-1 on cognitive function in septic encephalopathy.
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Effects of long-term dehydration on oxidative stress, apoptotic markers and neuropeptides in the gastric mucosa of the dromedary camel.
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Effects of matrine in combination with cisplatin on liver cancer.
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Effects of oxaliplatin on inflammation and intestinal floras in rats with colorectal cancer.
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Effects of trans-resveratrol on type 1 diabetes-induced up-regulation of apoptosis and mitogen-activated protein kinase signaling in retinal pigment epithelium of Dark Agouti rats.
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Effects of treatment of rats with indole-3-carbinol on apoptosis in the mammary gland and mammary adenocarcinomas.
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Efficacy of the chemotherapeutic action of HPMA copolymer-bound doxorubicin in a solid tumor model of ovarian carcinoma.
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Embelin: a benzoquinone possesses therapeutic potential for the treatment of human cancer.
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Emetine regulates the alternative splicing of caspase 9 in tumor cells.
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Engineered TCR-T Cell Immunotherapy in Anticancer Precision Medicine: Pros and Cons.
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Enhanced sensitivity to cytochrome c-induced apoptosis mediated by PHAPI in breast cancer cells.
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Enhanced susceptibility to apoptosis and growth arrest of human breast carcinoma cells treated by silica nanoparticles loaded with monohydroxy flavone compounds.
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Ent-Dihydrotucumanoic acid promotes apoptosis in PC-3 human prostate cancer cells.
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Epigenetic inactivation of BCL6B, a novel functional tumour suppressor for gastric cancer, is associated with poor survival of gastric cancer.
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Erinacine Facilitates the Opening of the Mitochondrial Permeability Transition Pore Through the Inhibition of the PI3K/ Akt/GSK-3? Signaling Pathway in Human Hepatocellular Carcinoma.
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Evaluation of Apoptosis Induction by Newcastle Disease Virus LaSota Strain in Human Breast Carcinoma Cells.
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Evaluation of Caspase-9b and PP2Ac?2 as potential biomarkers for chronic lymphocytic leukemia.
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Evaluation of the association between biochemical and immunohistochemical score of caspase-9 and TNF?, and the grading of lumbar disc herniation.
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Evaluation of the Potential Diagnostic Utility of the Determination of Selected Caspases-Markers Involved in the Regulation of Apoptosis-In Patients with Ovarian Cancer.
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Evidence of a novel antiapoptotic factor: role of inhibitor of differentiation or DNA binding (Id-1) in anticancer drug-induced apoptosis.
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Exposure of pregnant sows to deoxynivalenol during 35-70 days of gestation does not affect pathomorphological and immunohistochemical properties of fetal organs.
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Expression analysis of caspase-6, caspase-9 and BNIP3 in prostate cancer.
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Expression and prognostic significance of APAF-1, caspase-8 and caspase-9 in stage II/III colon carcinoma: Caspase-8 and caspase-9 is associated with poor prognosis.
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Expression levels of cleaved caspase-3 and caspase-3 in tumorigenesis and prognosis of oral tongue squamous cell carcinoma.
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Expression of c-Jun, p73, Casp9, and N-ras in thymic epithelial tumors: relationship with the current WHO classification systems.
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Failure of activation of caspase-9 induces a higher threshold for apoptosis and cisplatin resistance in testicular cancer.
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Features of the Copy Number Variation of Certain Genes in Tumor Cells in Patients with Serous Ovarian Adenocarcinoma.
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Fish oil improves learning impairments of diabetic rats by blocking PI3K/AKT/nuclear factor-?B-mediated inflammatory pathways.
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gamma-Tocopheryl quinone induces apoptosis in cancer cells via caspase-9 activation and cytochrome c release.
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Ganoderma atrum polysaccharide induces antitumor activity via the mitochondrial apoptotic pathway related to activation of host immune response.
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Gene expression signature of primary imatinib-resistant chronic myeloid leukemia patients.
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Gene expression study related with the intrinsic pathway of apoptosis in bladder cancer by real-time PCR technique.
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Gene-viro-therapy targeting liver cancer by a dual-regulated oncolytic adenoviral vector harboring IL-24 and TRAIL.
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Genetic determinants that influence hypoxia-induced apoptosis.
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Germacrone Inhibits Cell Proliferation and Induces Apoptosis in Human Esophageal Squamous Cell Carcinoma Cells.
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Glycosylation of anthocyanins enhances the apoptosis of colon cancer cells by handicapping energy metabolism.
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Gramine inhibits angiogenesis and induces apoptosis via modulation of TGF-? signalling in 7,12 dimethylbenz[a]anthracene (DMBA) induced hamster buccal pouch carcinoma.
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HBXIP, a binding protein of HBx, regulates maintenance of the G2/M phase checkpoint induced by DNA damage and enhances sensitivity to doxorubicin-induced cytotoxicity.
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Heat shock and tumor necrosis factor-alpha induce apoptosis in bovine preimplantation embryos through a caspase-9-dependent mechanism.
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Heat shock protein 70-2 (HSP70-2) a novel cancer testis antigen that promotes growth of ovarian cancer.
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Heat shock protein inhibitors increase the efficacy of measles virotherapy.
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Herbal formula of Bushen Jianpi combined with sorafenib inhibits hepatocellular carcinoma growth by promoting cell apoptosis and blocking the cell cycle.
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HGS-ETR1, a fully human TRAIL-receptor 1 monoclonal antibody, induces cell death in multiple tumour types in vitro and in vivo.
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High LET radiation enhances apoptosis in mutated p53 cancer cells through Caspase-9 activation.
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High-Resolution Magic Angle Spinning (1)H NMR Spectroscopy and Reverse Transcription-PCR Analysis of Apoptosis in a Rat Glioma.
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Hiltonol Cocktail Kills Lung Cancer Cells by Activating Cancer-Suppressors, PKR/OAS, and Restraining the Tumor Microenvironment.
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hnRNP L regulates the tumorigenic capacity of lung cancer xenografts in mice via caspase-9 pre-mRNA processing.
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Host-Defense Peptides Caerin 1.1 and 1.9 Stimulate TNF-Alpha-Dependent Apoptotic Signals in Human Cervical Cancer HeLa Cells.
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HSP70 inhibitor combined with cisplatin suppresses the cervical cancer proliferation in vitro and transplanted tumor growth: An experimental study.
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Human Chorionic Gonadotropin Suppresses Human Breast Cancer Cell Growth Directly via p53-mediated Mitochondrial Apoptotic Pathway and Indirectly via Ovarian Steroid Secretion.
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Human hepatocellular carcinoma in a mouse model: assessment of tumor response to percutaneous ablation by using glyceraldehyde-3-phosphate dehydrogenase antagonists.
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HuR-targeted small molecule inhibitor exhibits cytotoxicity towards human lung cancer cells.
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Hyperforin and aristoforin inhibit lymphatic endothelial cell proliferation in vitro and suppress tumor-induced lymphangiogenesis in vivo.
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Hypothyroidism reduces mammary tumor progression via ?-catenin-activated intrinsic apoptotic pathway in rats.
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Hypoxia-Inducible Factor 1-? (HIF-1?) Induces Apoptosis of Human Uterosacral Ligament Fibroblasts Through the Death Receptor and Mitochondrial Pathways.
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Hypoxic preconditioning potentiates the trophic effects of mesenchymal stem cells on co-cultured human primary hepatocytes.
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Identification of an antitumor effect of demethylzeylasteral on human gastric cancer cells.
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Identification of new compounds that trigger apoptosome-independent caspase activation and apoptosis.
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Ifosfamide-loaded lipid-core-nanocapsules to increase the anticancer efficacy in MG63 osteosarcoma cells.
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Imbalance of the mitochondrial pro- and anti-apoptotic mediators in neuroblastoma tumours with unfavourable biology.
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Immunocytochemical detection of members of the caspase cascade of apoptosis in high-grade astrocytomas.
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Immunocytochemical expression of a panel of markers in pleural effusions from patients with primary lung adenocarcinoma.
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Immunohistochemical expression of caspases 9 and 3 in adenoid cystic carcinoma of salivary glands and association with clinicopathological parameters.
Neoplasms
Immunoreactivity to caspase-3, caspase-7, caspase-8, and caspase-9 forms is frequently lost in human prostate tumors.
Neoplasms
Impact of Procyanidins from Different Berries on Caspase 8 Activation in Colon Cancer.
Neoplasms
Implication of calpain in caspase activation during B cell clonal deletion.
Neoplasms
Improved safety of induced pluripotent stem cell-derived antigen-presenting cell-based cancer immunotherapy.
Neoplasms
In situ activation and monitoring of the evolution of the intracellular caspase family.
Neoplasms
In vitro and in vivo anti-cancer activities of Kuding tea (Ilex kudingcha C.J. Tseng) against oral cancer.
Neoplasms
In vitro Anticancer Effects of Stilbene Derivatives: Mechanistic Studies on HeLa and MCF-7 Cells.
Neoplasms
In vitro infection of bovine monocytes with Mycoplasma bovis delays apoptosis and suppresses production of gamma interferon and tumor necrosis factor alpha but not interleukin-10.
Neoplasms
Inactivated Sendai Virus Strain Tianjin Induces Apoptosis in Breast Cancer MCF-7 Cells by Promoting Caspase Activation and Fas/FasL Expression.
Neoplasms
Increased autophagy in EOC re-ascites cells can inhibit cell death and promote drug resistance.
Neoplasms
Indole-3-carbinol inhibits nasopharyngeal carcinoma.
Neoplasms
Induction of apoptosis and down-regulation of Bcl-XL in cancer cells by a novel small molecule, 2[[3-(2,3-dichlorophenoxy)propyl]amino]ethanol.
Neoplasms
Induction of apoptosis in cancer cells by NiZn ferrite nanoparticles through mitochondrial cytochrome C release.
Neoplasms
Induction of apoptosis of human lung carcinoma cells by hybrid liposomes containing polyoxyethylenedodecyl ether.
Neoplasms
Induction of caspase-9, biochemical assessment and morphological changes caused by apoptosis in cancer cells treated with goniothalamin extracted from Goniothalamus macrophyllus.
Neoplasms
Induction of endoplasmic reticulum stress and apoptosis by a marine prostanoid in human hepatocellular carcinoma.
Neoplasms
Influence of a leptin deficiency on testicular morphology, germ cell apoptosis, and expression levels of apoptosis-related genes in the mouse.
Neoplasms
Influence of caspases 8 and 9 gene promoter polymorphism on prostate cancer susceptibility and early development of hormone refractory prostate cancer.
Neoplasms
Inhibition of caspase-9 by oridonin, a diterpenoid isolated from Rabdosia rubescens, augments apoptosis in human laryngeal cancer cells.
Neoplasms
Inhibition of human glioma U251 cells growth in vitro and in vivo by hydroxyapatite nanoparticle-assisted delivery of short hairpin RNAs against SATB1.
Neoplasms
Inhibition of mammary tumor growth by estrogens: is there a specific role for estrogen receptors alpha and beta?
Neoplasms
Inhibition of non-neuronal alpha7-nicotinic receptor reduces tumorigenicity in A549 NSCLC xenografts.
Neoplasms
Inhibition of phosphotidylinositol-3 kinase pathway by a novel naphthol derivative of betulinic acid induces cell cycle arrest and apoptosis in cancer cells of different origin.
Neoplasms
Inhibition of Stat3 Activity by YC-1 Enhances Chemo-Sensitivity in Hepatocellular Carcinoma.
Neoplasms
Inhibitor of apoptosis protein-1 promotes tumor cell survival in mesothelioma.
Neoplasms
Inhibitors of apoptosis confer resistance to tumour suppression by adoptively transplanted cytotoxic T-lymphocytes in vitro and in vivo.
Neoplasms
Inhibitory activity of acteoside in melanoma via regulation of the ER?-Ras/Raf1-STAT3 pathway.
Neoplasms
Inhibitory activity of flaxseed oil against CdCl2 induced liver and kidney damage: Histopathology, genotoxicity, and gene expression study.
Neoplasms
Integrative in silico and in vitro transcriptomics analysis revealed new lncRNAs related to intrinsic apoptotic genes in colorectal cancer.
Neoplasms
Intra-arterially infused carbon dioxide-saturated solution for sensitizing the anticancer effect of cisplatin in a rabbit VX2 liver tumor model.
Neoplasms
Intranasal Administration of Type V Collagen Reduces Lung Carcinogenesis through Increasing Endothelial and Epithelial Apoptosis in a Urethane-Induced Lung Tumor Model.
Neoplasms
Investigation of the Inhibitory Effect of Platycodin D in Human Transitional Cell Carcinoma Cell Line 5637.
Neoplasms
Investigation of U-251 cell death triggered by flavonoid luteolin: towards a better understanding on its anticancer property against glioblastomas.
Neoplasms
In vivo and in vitro inhibition of human gastric cancer progress by upregulating Kank1 gene.
Neoplasms
Isolation of 4,4'-bond secalonic acid D from the marine-derived fungus Penicillium oxalicum with inhibitory property against hepatocellular carcinoma.
Neoplasms
JNK2 silencing and caspase-9 activation by hyperosmotic polymer inhibits tumor progression.
Neoplasms
Lentivirus-mediated RNA interference targeting E2F-1 inhibits human gastric cancer MGC-803 cell growth in vivo.
Neoplasms
Licochalcone-E induces caspase-dependent death of human pharyngeal squamous carcinoma cells through the extrinsic and intrinsic apoptotic signaling pathways.
Neoplasms
Lipid Nanocarriers of a Lipid-Conjugated Estrogenic Derivative Inhibit Tumor Growth and Enhance Cisplatin Activity against Triple-Negative Breast Cancer: Pharmacokinetic and Efficacy Evaluation.
Neoplasms
LncRNA POU3F3 promotes proliferation and inhibits apoptosis of cancer cells in triple-negative breast cancer by inactivating caspase 9.
Neoplasms
Long non-coding RNA LINC00607 silencing exerts antioncogenic effects on thyroid cancer through the CASP9 Promoter methylation.
Neoplasms
Long noncoding RNA LINC00662-miR-15b-5p mediated GPR120 dysregulation contributes to osteoarthritis.
Neoplasms
Loss of caspase-8 protein expression correlates with unfavorable survival outcome in childhood medulloblastoma.
Neoplasms
Loss of caspase-9 reveals its essential role for caspase-2 activation and mitochondrial membrane depolarization.
Neoplasms
Low concentrations of trichosanthin induce apoptosis and cell cycle arrest via c-Jun N-terminal protein kinase/mitogen-activated protein kinase activation.
Neoplasms
Low-dose naltrexone inhibits colorectal cancer progression and promotes apoptosis by increasing M1-type macrophages and activating the Bax/Bcl-2/caspase-3/PARP pathway.
Neoplasms
Major Contribution of Caspase-9 to Honokiol-Induced Apoptotic Insults to Human Drug-Resistant Glioblastoma Cells.
Neoplasms
MAPT (Tau) expression is a biomarker for an increased rate of survival in pediatric neuroblastoma.
Neoplasms
Marker genes to predict sensitivity to FK228, a histone deacetylase inhibitor.
Neoplasms
mda-7/IL-24 induces apoptosis in human GBC-SD gallbladder carcinoma cells via mitochondrial apoptotic pathway.
Neoplasms
Mechanism of action for N-substituted benzamide-induced apoptosis.
Neoplasms
Metastasized lung cancer suppression by Morinda citrifolia (Noni) leaf compared to Erlotinib via anti-inflammatory, endogenous antioxidant responses and apoptotic gene activation.
Neoplasms
Method to Measure Sphingomyelin Synthase Activity Changes in Response to CD95L.
Neoplasms
MicroRNA-7641 is a regulator of ribosomal proteins and a promising targeting factor to improve the efficacy of cancer therapy.
Neoplasms
MicroRNA-based recombinant AAV vector assembly improves efficiency of suicide gene transfer in a murine model of lymphoma.
Neoplasms
miR-1269 promotes cell survival and proliferation by targeting tp53 and caspase-9 in lung cancer.
Neoplasms
MiR-153 promotes breast cancer cell apoptosis by targeting HECTD3.
Neoplasms
miR-187-5p/apaf-1 axis was involved in oxidative stress-mediated apoptosis caused by ammonia via mitochondrial pathway in chicken livers.
Neoplasms
Mitochondrial dysfunction mediated apoptosis of HT-29 cells through CS-PAC-AgNPs and investigation of genotoxic effects in zebra (Danio rerio) fish model for drug delivery.
Neoplasms
Mitochondrial targeting liposomes incorporating daunorubicin and quinacrine for treatment of relapsed breast cancer arising from cancer stem cells.
Neoplasms
Mitogen-activated protein kinase phosphatase-1 prevents lipopolysaccharide-induced apoptosis in immature rat intestinal epithelial cells.
Neoplasms
Modulation of Apoptosis by Cytotoxic Mediators and Cell-Survival Molecules in Sjögren's Syndrome.
Neoplasms
Molecular evidence of apoptotic death in malignant brain tumors including glioblastoma multiforme: upregulation of calpain and caspase-3.
Neoplasms
Monascus purpureus induced apoptosis on gastric cancer cell by scavenging mitochondrial reactive oxygen species.
Neoplasms
Monocyte survival factors induce Akt activation and suppress caspase-3.
Neoplasms
Moringa Oleifera Gold Nanoparticles Modulate Oncogenes, Tumor Suppressor Genes and Caspase-9 Splice Variants in A549 Cells.
Neoplasms
mRNA Expression of Bax, Bcl-2, p53, Cathepsin B, Caspase-3 and Caspase-9 in the HepG2 Cell Line Following Induction by a Novel Monoclonal Ab Hep88 mAb: Cross-Talk for Paraptosis and Apoptosis.
Neoplasms
Multiple effects of hyperbaric oxygen on the expression of HIF-1 alpha and apoptotic genes in a global ischemia-hypotension rat model.
Neoplasms
Mutational analysis of proapoptotic caspase-9 gene in common human carcinomas.
Neoplasms
Myrtucommulone from Myrtus communis induces apoptosis in cancer cells via the mitochondrial pathway involving caspase-9.
Neoplasms
MytiLec, a Mussel R-Type Lectin, Interacts with Surface Glycan Gb3 on Burkitt's Lymphoma Cells to Trigger Apoptosis through Multiple Pathways.
Neoplasms
Nanomedicine-based paclitaxel induced apoptotic signaling pathways in A562 leukemia cancer cells.
Neoplasms
Natural Infection with Rabies Virus: A Histopathological and Immunohistochemical Study of Human Brains.
Neoplasms
Neratinib and entinostat combine to rapidly reduce the expression of K-RAS, N-RAS, G?q and G?11 and kill uveal melanoma cells.
Neoplasms
Neuroprotection of netrin-1 on neurological recovery via Wnt/?-catenin signaling pathway after spinal cord injury.
Neoplasms
New chalcone derivative exhibits antiproliferative potential by inducing G2/M cell cycle arrest, mitochondrial-mediated apoptosis and modulation of MAPK signalling pathway.
Neoplasms
NF-?B pathway took part in the development of apoptosis mediated by miR-15a and oxidative stress via mitochondrial pathway in ammonia-treated chicken splenic lymphocytes.
Neoplasms
NF-kappaB does not influence the induction of apoptosis by ukrain.
Neoplasms
Novel anticancer activity of the autocleaved ovotransferrin against human colon and breast cancer cells.
Neoplasms
Novel ent-Kaurane Diterpenoid from Rubus corchorifolius L. f. Inhibits Human Colon Cancer Cell Growth via Inducing Cell Cycle Arrest and Apoptosis.
Neoplasms
Novel functional profiling approach combining reverse phase protein microarrays and human 3-D ex vivo tissue cultures: expression of apoptosis-related proteins in human colon cancer.
Neoplasms
Novel mechanism of hybrid liposomes-induced apoptosis in human tumor cells.
Neoplasms
Novel polysaccharide extracted from Sipunculus nudus inhibits HepG2 tumour growth in vivo by enhancing immune function and inducing tumour cell apoptosis.
Neoplasms
Oral treatment with herbal formula B307 alleviates cardiac failure in aging R6/2 mice with Huntington's disease via suppressing oxidative stress, inflammation, and apoptosis.
Neoplasms
Oral treatment with the herbal formula B307 alleviates cardiac toxicity in doxorubicin-treated mice via suppressing oxidative stress, inflammation, and apoptosis.
Neoplasms
Over-expression of APAF-1 and caspase-9 augments radiation-induced apoptosis in U-373MG glioma cells.
Neoplasms
Overcoming drug-resistant lung cancer by paclitaxel loaded dual-functional liposomes with mitochondria targeting and pH-response.
Neoplasms
Overexpression of caspase-9 triggers its activation and apoptosis in vitro.
Neoplasms
P2X7 receptor-mediated apoptosis of human cervical epithelial cells.
Neoplasms
p53-dependent Fas expression is critical for Ginsenoside Rh2 triggered caspase-8 activation in HeLa cells.
Neoplasms
PANC-1 cancer stem-like cell death with silybin encapsulated in polymersomes and deregulation of stemness-related miRNAs and their potential targets.
Neoplasms
Parasporin-2 from a New Bacillus thuringiensis 4R2 Strain Induces Caspases Activation and Apoptosis in Human Cancer Cells.
Neoplasms
Peptide-functionalized upconversion nanoparticles-based FRET sensing platform for Caspase-9 activity detection in vitro and in vivo.
Neoplasms
PHAPI, CAS, and Hsp70 promote apoptosome formation by preventing Apaf-1 aggregation and enhancing nucleotide exchange on Apaf-1.
Neoplasms
Phosphorylation of murine caspase-9 by the protein kinase casein kinase 2 regulates its cleavage by caspase-8.
Neoplasms
Photodynamic Therapy of Pheophorbide a Inhibits the Proliferation of Human Breast Tumour via Both Caspase-dependent and -independent Apoptotic Pathways in In Vitro and In Vivo Models.
Neoplasms
Photodynamic therapy with the phthalocyanine photosensitizer Pc 4 of SW480 human colon cancer xenografts in athymic mice.
Neoplasms
Photoluminescent And Self-Assembled Hyaluronic Acid-Zinc Oxide-Ginsenoside Rh2 Nanoparticles And Their Potential Caspase-9 Apoptotic Mechanism Towards Cancer Cell Lines.
Neoplasms
Phytol induces ROS mediated apoptosis by induction of caspase 9 and 3 through activation of TRAIL, FAS and TNF receptors and inhibits tumor progression factor Glucose 6 phosphate dehydrogenase in lung carcinoma cell line (A549).
Neoplasms
Pim-1 plays a pivotal role in hypoxia-induced chemoresistance.
Neoplasms
Polyclonal rabbit anti-human ovarian cancer globulins inhibit tumor growth through apoptosis involving the caspase signaling.
Neoplasms
Polymorphisms of Caspase 8 and Caspase 9 gene and colorectal cancer susceptibility and prognosis.
Neoplasms
Polyphyllin I inhibits the growth of ovarian cancer cells in nude mice.
Neoplasms
Pomegranate exerts chemoprevention of experimentally induced mammary tumorigenesis by suppression of cell proliferation and induction of apoptosis.
Neoplasms
Potent Antitumor Activity of Oncolytic Adenovirus Expressing mda-7/IL-24 for Colorectal Cancer.
Neoplasms
Potent antitumor activity of oncolytic adenovirus expressing mda-7/IL-24 for colorectal cancer.
Neoplasms
Potential role of Notch1 signaling pathway in laryngeal squamous cell carcinoma cell line Hep-2 involving proliferation inhibition, cell cycle arrest, cell apoptosis, and cell migration.
Neoplasms
Prefrontal Cortex and Hippocampus Inflammation in Mice Fed High-Carbohydrate or High-Fat Diets.
Neoplasms
Preparation of curcumin micelles and the in vitro and in vivo evaluation for cancer therapy.
Neoplasms
Preparation, Characterization and In-vitro Biological Evaluation of Novel Curcumin Derivatives as Cytotoxic and Apoptosis-Inducing Agents.
Neoplasms
Preparation, Optimization and In-Vitro Evaluation of Curcumin-Loaded Niosome@calcium Alginate Nanocarrier as a New Approach for Breast Cancer Treatment.
Neoplasms
Progesterone induces apoptosis by activation of caspase-8 and calcitriol via activation of caspase-9 pathways in ovarian and endometrial cancer cells in vitro.
Neoplasms
Proliferation index: a continuous model to predict prognosis in patients with tumours of the Ewing's sarcoma family.
Neoplasms
Protection of mitochondrial perturbation by human T-lymphotropic virus type 1 tax through induction of Bcl-xL expression.
Neoplasms
Protective effect of 5-HT7 receptor activation against glutamate-induced neurotoxicity in human neuroblastoma SH-SY5Y cells via antioxidative and antiapoptotic pathways.
Neoplasms
Protective effect of cannabidiol against cadmium hepatotoxicity in rats.
Neoplasms
Protective effects of dioscin against alcohol-induced liver injury.
Neoplasms
Protective effects of miR-155-5p silencing on IFN-?-induced apoptosis and inflammation in salivary gland epithelial cells.
Neoplasms
Protective effects of St. John's wort in the hepatic ischemia/reperfusion injury in rats.
Neoplasms
Protective effects of the ethanolic extract of Melia toosendan fruit against colon cancer.
Neoplasms
Protein kinase C inhibitor and irradiation-induced apoptosis: relevance of the cytochrome c-mediated caspase-9 death pathway.
Neoplasms
Protein kinase C-eta regulates resistance to UV- and gamma-irradiation-induced apoptosis in glioblastoma cells by preventing caspase-9 activation.
Neoplasms
Proteomic and transcriptomic study on the action of a cytotoxic saponin (Polyphyllin D): induction of endoplasmic reticulum stress and mitochondria-mediated apoptotic pathways.
Neoplasms
Pt(II) complexes of a combretastatin A-4 analogous chalcone: effects of conjugation on cytotoxicity, tumor specificity, and long-term tumor growth suppression.
Neoplasms
Radix Tetrastigma Inhibits the Non-Small Cell Lung Cancer via Bax/Bcl-2/Caspase-9/Caspase-3 Pathway.
Neoplasms
Rationally Repurposing Ruxolitinib (Jakafi (®)) as a Solid Tumor Therapeutic.
Neoplasms
Recombinant adenovirus Ad-RUNrf2 reduces paraquat-induced A549 injury.
Neoplasms
Relationship Between CASP9 and CASP10 Gene Polymorphisms and Cancer Susceptibility: Evidence from an Updated Meta-analysis.
Neoplasms
Relationship of possible biomarkers with malignancy of thymic tumors: a meta-analysis.
Neoplasms
Renal Cell Carcinoma Tumors Induce T Cell Apoptosis through Receptor-Dependent and Receptor-Independent Pathways.
Neoplasms
Requirement of BAX for TRAIL/Apo2L-induced apoptosis of colorectal cancers: synergism with sulindac-mediated inhibition of Bcl-x(L).
Neoplasms
Resistance of human astrocytoma cells to apoptosis induced by mitochondria-damaging agents: possible implications for anticancer therapy.
Neoplasms
Retinoic acid amide inhibits JAK/STAT pathway in lung cancer which leads to apoptosis.
Neoplasms
Rhein Augments Antiproliferative Effects of Atezolizumab Based on Breast Cancer (4T1) Regression.
Neoplasms
Role of the CASP-9 Ex5+32 G>A polymorphism in susceptibility to cancer: A meta-analysis.
Neoplasms
Role of TLR4/MyD88/NF-?B signaling in the contrast-induced injury of renal tubular epithelial cells.
Neoplasms
S-allylmercaptocysteine promotes MAPK inhibitor-induced apoptosis by activating the TGF-? signaling pathway in cancer cells.
Neoplasms
SB203580 Modulates p38 MAPK Signaling and Dengue Virus-Induced Liver Injury by Reducing MAPKAPK2, HSP27, and ATF2 Phosphorylation.
Neoplasms
Scinderin is a novel transcriptional target of BRMS1 involved in regulation of hepatocellular carcinoma cell apoptosis.
Neoplasms
Secretory leukoprotease inhibitor inhibits cell growth through apoptotic pathway on ovarian cancer.
Neoplasms
Sensitization of tumor cells to Apo2 ligand/TRAIL-induced apoptosis by inhibition of casein kinase II.
Neoplasms
Shrimp shells extracted chitin in silver nanoparticle synthesis: Expanding its prophecy towards anticancer activity in human hepatocellular carcinoma HepG2 cells.
Neoplasms
Silencing Bcl-2 in models of mantle cell lymphoma is associated with decreases in cyclin D1, nuclear factor-kappaB, p53, bax, and p27 levels.
Neoplasms
Silver oxide nanoparticles alleviate indomethacin-induced gastric injury: a novel antiulcer agent.
Neoplasms
Sinoporphyrin Sodium-Mediated Sonodynamic Therapy Inhibits RIP3 Expression and Induces Apoptosis in the H446 Small Cell Lung Cancer Cell Line.
Neoplasms
SKLB316, a novel small-molecule inhibitor of cell-cycle progression, induces G2/M phase arrest and apoptosis in vitro and inhibits tumor growth in vivo.
Neoplasms
SL-01, an oral gemcitabine derivative, inhibited human cancer growth more potently than gemcitabine.
Neoplasms
Solenopsin, the alkaloidal component of the fire ant (Solenopsis invicta), is a naturally occurring inhibitor of phosphatidylinositol-3-kinase signaling and angiogenesis.
Neoplasms
Splicing factors of SR and hnRNP families as regulators of apoptosis in cancer.
Neoplasms
SRSF1 Regulates the Alternative Splicing of Caspase 9 Via A Novel Intronic Splicing Enhancer Affecting the Chemotherapeutic Sensitivity of Non-Small Cell Lung Cancer Cells.
Neoplasms
Stomach cancer highly expresses both initiator and effector caspases; an immunohistochemical study.
Neoplasms
Strawberry Leaf Extract Treatment Alleviates Cognitive Impairment by Activating Nrf2/HO-1 Signaling in Rats With Streptozotocin-Induced Diabetes.
Neoplasms
Structure, cytotoxic activity and mechanism of protoilludane sesquiterpene aryl esters from the mycelium of Armillaria mellea.
Neoplasms
Stryphnodendron adstringens ("Barbatimão") Leaf Fraction: Chemical Characterization, Antioxidant Activity, and Cytotoxicity Towards Human Breast Cancer Cell Lines.
Neoplasms
Study of RNA Interference Targeting NET-1 Combination with Sorafenib for Hepatocellular Carcinoma Therapy In Vitro and In Vivo.
Neoplasms
Study on the anti-hepatocarcinoma effect and molecular mechanism of Prunella vulgaris total flavonoids.
Neoplasms
Suberoylanilide hydroxamic acid increases anti-cancer effect of tumor necrosis factor-? through up-regulation of TNF receptor 1 in lung cancer cells.
Neoplasms
Sulindac enhances adenoviral vector expressing mda-7/IL-24-mediated apoptosis in human lung cancer.
Neoplasms
Suppressing effects of daily oral supplementation of beta-glucan extracted from Agaricus blazei Murill on spontaneous and peritoneal disseminated metastasis in mouse model.
Neoplasms
Suppression of mammary gland carcinogenesis by post-initiation treatment of rats with tamoxifen or indole-3-carbinol or their combination.
Neoplasms
Synergistic Anticancer Effects of Formononetin and Temozolomide on Glioma C6 Cells.
Neoplasms
Synergistic tumor growth-inhibitory effect of the prostate-specific antigen-activated fusion peptide BSD352 for prostate cancer therapy.
Neoplasms
Synthesis of Tolmetin Hydrazide-Hydrazones and Discovery of a Potent Apoptosis Inducer in Colon Cancer Cells.
Neoplasms
Synthesis, characterization, and anticancer activity of Schiff bases.
Neoplasms
Synthetic 1,4-anthracenedione analogs induce cytochrome c release, caspase-9, -3, and -8 activities, poly(ADP-ribose) polymerase-1 cleavage and internucleosomal DNA fragmentation in HL-60 cells by a mechanism which involves caspase-2 activation but not Fas signaling.
Neoplasms
t-Darpp promotes cancer cell survival by up-regulation of Bcl2 through Akt-dependent mechanism.
Neoplasms
Tanshinone IIA inhibits human gastric carcinoma AGS cell growth by decreasing BiP, TCTP, Mcl?1 and Bcl?xL and increasing Bax and CHOP protein expression.
Neoplasms
Targeted apoptotic effects of thymoquinone and tamoxifen on XIAP mediated Akt regulation in breast cancer.
Neoplasms
Targeting Bcl-xL in esophageal squamous cancer to sensitize to chemotherapy plus TRAIL-induced apoptosis while normal epithelial cells are protected by blockade of caspase 9.
Neoplasms
Targeting CPT1A-mediated fatty acid oxidation sensitizes nasopharyngeal carcinoma to radiation therapy.
Neoplasms
TAS4464, a NEDD8-activating enzyme inhibitor, activates both intrinsic and extrinsic apoptotic pathways via c-Myc-mediated regulation in acute myeloid leukemia.
Neoplasms
Taurine Attenuates Carcinogenicity in Ulcerative Colitis-Colorectal Cancer Mouse Model.
Neoplasms
TGF-?1 protection against A?1-42-induced hippocampal neuronal inflammation and apoptosis by T?R-I.
Neoplasms
The alkylphospholipid perifosine induces apoptosis of human lung cancer cells requiring inhibition of Akt and activation of the extrinsic apoptotic pathway.
Neoplasms
The anti-tumor activities of cerebrosides derived from sea cucumber Acaudina molpadioides and starfish Asterias amurensis in vitro and in vivo.
Neoplasms
The antiangiogenic agent Neovastat (AE-941) induces endothelial cell apoptosis.
Neoplasms
The AP-2alpha transcription factor regulates tumor cell migration and apoptosis.
Neoplasms
The bioactive ingredients in Actinidia chinensis Planch. Inhibit liver cancer by inducing apoptosis.
Neoplasms
The Birc6 (Bruce) gene regulates p53 and the mitochondrial pathway of apoptosis and is essential for mouse embryonic development.
Neoplasms
The caspase 9 inhibitor Z-LEHD-FMK protects human liver cells while permitting death of cancer cells exposed to tumor necrosis factor-related apoptosis-inducing ligand.
Neoplasms
The combination effects of Shen-Ling-Bai-Zhu on promoting apoptosis of transplanted H22 hepatocellular carcinoma in mice receiving chemotherapy.
Neoplasms
The effect of fatty acid-CoA ligase 4 on the growth of hepatic cancer cells.
Neoplasms
The effect of salmon calcitonin against glutamate-induced cytotoxicity in the C6 cell line and the roles the inflammatory and nitric oxide pathways play.
Neoplasms
The growth of the canine glioblastoma cell line D-GBM and the canine histiocytic sarcoma cell line DH82 is inhibited by the resveratrol oligomers hopeaphenol and r2-viniferin.
Neoplasms
The interaction between the light source dose and caspase-dependent and -independent apoptosis in human SK-MEL-3 skin cancer cells following photodynamic therapy with zinc phthalocyanine: A comparative study.
Neoplasms
The long noncoding RNA XIAP-AS1 promotes XIAP transcription by XIAP-AS1 interacting with Sp1 in gastric cancer cells.
Neoplasms
The lysophosphatidic acid type 2 receptor is required for protection against radiation-induced intestinal injury.
Neoplasms
The mitochondria-targeting antioxidant MitoQ alleviated Lipopolysaccharide/ D-galactosamine-induced acute liver injury in mice.
Neoplasms
The non-apoptotic role of caspase-9 promotes differentiation in leukemic cells.
Neoplasms
The Novel Akt Inhibitor API-1 Induces c-FLIP Degradation and Synergizes with TRAIL to Augment Apoptosis Independent of Akt Inhibition.
Neoplasms
The potential tumour suppressor role for caspase-9 (CASP9) in the childhood malignancy, neuroblastoma.
Neoplasms
The scorpion venom peptide BmKn2 induces apoptosis in cancerous but not in normal human oral cells.
Neoplasms
The sirtuin 1 activator SRT1720 alleviated endotoxin-induced fulminant hepatitis in mice.
Neoplasms
The use of mitochondrial targeting resveratrol liposomes modified with a dequalinium polyethylene glycol-distearoylphosphatidyl ethanolamine conjugate to induce apoptosis in resistant lung cancer cells.
Neoplasms
Therapeutic effect and apoptosis mechanism of lung-tonifying and expectorant decoction on lung cancer rats with Qi deficiency and blood stasis.
Neoplasms
Thiamine Alleviates High-Concentrate-Diet-Induced Oxidative Stress, Apoptosis, and Protects the Rumen Epithelial Barrier Function in Goats.
Neoplasms
Three immunomarker support vector machines-based prognostic classifiers for stage IB non-small-cell lung cancer.
Neoplasms
Thymoquinone ameliorates testicular tissue inflammation induced by chronic administration of oral sodium nitrite.
Neoplasms
Toll-like receptor 4 mediates the antitumor host response induced by Ganoderma atrum polysaccharide.
Neoplasms
TRAIL death receptors DR4 and DR5 mediate cerebral microvascular endothelial cell apoptosis induced by oligomeric Alzheimer's A?.
Neoplasms
Transcript expression and genetic variability analysis of caspases in breast carcinomas suggests CASP9 as the most interesting target.
Neoplasms
Transcutaneous application of carbon dioxide (CO2) induces mitochondrial apoptosis in human malignant fibrous histiocytoma in vivo.
Neoplasms
Transferrin-Conjugated Erianin-Loaded Liposomes Suppress the Growth of Liver Cancer by Modulating Oxidative Stress.
Neoplasms
TRIAP1 Inhibition Activates the Cytochrome c/Apaf-1/Caspase-9 Signaling Pathway to Enhance Human Ovarian Cancer Sensitivity to Cisplatin.
Neoplasms
Trichinella pseudospiralis infection is characterized by more continuous and diffuse myopathy than T. spiralis infection.
Neoplasms
Trichosanthin inhibits breast cancer cell proliferation in both cell lines and nude mice by promotion of apoptosis.
Neoplasms
TUCAN/CARDINAL/CARD8 and apoptosis resistance in non-small cell lung cancer cells.
Neoplasms
Tumor cells suppress radiation-induced immunity by hijacking caspase 9 signaling.
Neoplasms
Tumor growth suppressive effect of IL-4 through p21-mediated activation of STAT6 in IL-4R? overexpressed melanoma models.
Neoplasms
Tumor necrosis factor-related apoptosis-inducing ligand additive with Iodine-131 of inhibits non-small cell lung cancer cells through promoting apoptosis.
Neoplasms
Tumor prone phenotype of mice deficient in a novel apoptosis-inducing gene, drs.
Neoplasms
Tumor-induced apoptosis of T cells: amplification by a mitochondrial cascade.
Neoplasms
Tumor-suppressive effect of adenovirus-mediated inhibitor of growth 4 gene transfer in breast carcinoma cells in vitro and in vivo.
Neoplasms
Tumor-targeted Nanoparticle Delivery of HuR siRNA Inhibits Lung Tumor Growth In Vitro and In Vivo By Disrupting the Oncogenic Activity of the RNA-binding Protein HuR.
Neoplasms
Tuning of apoptosis-mediator gene transcription in HepG2 human hepatoma cells through an adenosine signal.
Neoplasms
Two Trichothecene Mycotoxins from Myrothecium roridum Induce Apoptosis of HepG-2 Cells via Caspase Activation and Disruption of Mitochondrial Membrane Potential.
Neoplasms
Upregulation of CASP9 through NF-?B and Its Target MiR-1276 Contributed to TNF?-promoted Apoptosis of Cancer Cells Induced by Doxorubicin.
Neoplasms
Valproate augments Niraparib killing of tumor cells.
Neoplasms
Verteporfin inhibits cell proliferation and induces apoptosis in different subtypes of breast cancer cell lines without light activation.
Neoplasms
Wild-type and mutant p53 mediate cisplatin resistance through interaction and inhibition of active caspase-9.
Neoplasms
Zinc chloride inhibits human lens epithelial cell migration and proliferation involved in TGF-?1 and TNF-? signaling pathways in HLE B-3 cells.
Neoplasms
Zirconia Nanoparticles Induce HeLa Cell Death Through Mitochondrial Apoptosis and Autophagy Pathways Mediated by ROS.
Neoplasms
[Anti-hepatoma effects of Smac analogue Birinapant and its related molecular mechanism].
Neoplasms
[Clinical and Functional Importance of Selected CASP8 and CASP9 Polymorphisms in Breast Carcinoma].
Neoplasms
[Effect of Ferula ferulaeoides on growth and apoptosis of human gastric cancer MGC-803 transplantation tumor in nude mice].
Neoplasms
[Effect of p38MAPK gene silencing on expression of oncogenes and apoptotic genes induced by PM(2.5) in hepatocytes].
Neoplasms
[Effects of Buzhong Yiqi decoction on expression of Bad, NF-?B, caspase-9, Survivin, and mTOR in nude mice with A549/DDP transplantation tumors].
Neoplasms
[Expression of caspase 9 and p53 in uterine leiomyosarcomas].
Neoplasms
[Expressions and clinical significances of iASPP and caspase-9 in esophageal cancer].
Neoplasms
[iPSC-derived rejuvenated T-cell therapy for Epstein-Barr virus-associated lymphomas].
Neoplasms
[Mda-7-carrying replication-defective adenovirus selectively kills hepatocellular carcinoma cells by facilitating release of proapoptotic protein from mitochondria]
Neoplasms
[Studies on mechanism of myricetin-induced apoptosis in human hepatocellular carcinoma HepG-2 cells]
Neoplasms
[Study on Apoptosis of Oral Squamous Carcinoma Cell line KB and KBv200 induced by Survivin RNAi.]
Neoplasms
[Synergistic effects and mechanisms of combined tumor necrosis factor-related apoptosis-inducing ligand and chemotherapeutic drugs or radiotherapy in killing laryngeal squamous carcinoma cells in vitro]
Neoplasms
[The role for oxidative stress in neurodegenerative diseases]
Neoplasms
{beta}2-Microglobulin Is a Signaling and Growth-Promoting Factor for Human Prostate Cancer Bone Metastasis.
Neoplasms, Germ Cell and Embryonal
Failure of activation of caspase-9 induces a higher threshold for apoptosis and cisplatin resistance in testicular cancer.
Nervous System Diseases
Caspase-9: A Multimodal Therapeutic Target With Diverse Cellular Expression in Human Disease.
Neural Tube Defects
Genetic screening and functional analysis of CASP9 mutations in a Chinese cohort with neural tube defects.
Neural Tube Defects
Key apoptotic genes APAF1 and CASP9 implicated in recurrent folate-resistant neural tube defects.
Neural Tube Defects
Rare mutations inapoptosis related genes APAF1, CASP9, and CASP3 contribute to human neural tube defects.
Neural Tube Defects
The role of cell death in regulating the size and shape of the mammalian forebrain.
Neurilemmoma
Gene therapy with apoptosis-associated speck-like protein (ASC), a newly described schwannoma tumor suppressor, inhibits schwannoma growth in vivo.
Neuroblastoma
A highly bioactive lignophenol derivative from bamboo lignin exhibits a potent activity to suppress apoptosis induced by oxidative stress in human neuroblastoma SH-SY5Y cells.
Neuroblastoma
Aggressive childhood neuroblastomas do not express caspase-8: an important component of programmed cell death.
Neuroblastoma
Analyses of apoptotic regulators CASP9 and DFFA at 1P36.2, reveal rare allele variants in human neuroblastoma tumours.
Neuroblastoma
Anandamide-induced cell death in primary neuronal cultures: role of calpain and caspase pathways.
Neuroblastoma
Apoptotic signaling in dopamine-induced cell death: the role of oxidative stress, p38 mitogen-activated protein kinase, cytochrome c and caspases.
Neuroblastoma
Caspase-9 and Apaf-1 are expressed and functionally active in human neuroblastoma tumor cell lines with 1p36 LOH and amplified MYCN.
Neuroblastoma
CdSe quantum dots induce apoptosis in human neuroblastoma cells via mitochondrial-dependent pathways and inhibition of survival signals.
Neuroblastoma
Chemotherapy-induced apoptosis of S-type neuroblastoma cells requires caspase-9 and is augmented by CD95/Fas stimulation.
Neuroblastoma
Curcumin inhibits oxidative stress-induced TRPM2 channel activation, calcium ion entry and apoptosis values in SH-SY5Y neuroblastoma cells: Involvement of transfection procedure.
Neuroblastoma
DNA-damaging drug-induced apoptosis sensitized by N-myc in neuroblastoma cells.
Neuroblastoma
Ellagic acid induces a dose- and time-dependent depolarization of mitochondria and activation of caspase-9 and -3 in human neuroblastoma cells.
Neuroblastoma
Essential Role for p53 and Caspase-9 in DNA Damaging Drug-Induced Apoptosis in Neuroblastoma IMR32 Cells.
Neuroblastoma
Inhibition of gamma ray-induced apoptosis by stimulatory heterotrimeric GTP binding protein involves Bcl-xL down-regulation in SH-SY5Y human neuroblastoma cells.
Neuroblastoma
Insulin promotes survival of amyloid-beta oligomers neuroblastoma damaged cells via caspase 9 inhibition and Hsp70 upregulation.
Neuroblastoma
Introducing point mutations into the ATGs of the putative open reading frames of the HSV-1 gene encoding the latency associated transcript (LAT) reduces its anti-apoptosis activity.
Neuroblastoma
Isobavachalcone, a chalcone constituent of Angelica keiskei, induces apoptosis in neuroblastoma.
Neuroblastoma
Ketamine induces apoptosis via the mitochondrial pathway in human lymphocytes and neuronal cells.
Neuroblastoma
Leucine to proline substitution by SNP at position 197 in Caspase-9 gene expression leads to neuroblastoma: a bioinformatics analysis.
Neuroblastoma
Lig-8, a highly bioactive lignophenol derivative from bamboo lignin, exhibits multifaceted neuroprotective activity.
Neuroblastoma
Lyssavirus matrix protein induces apoptosis by a TRAIL-dependent mechanism involving caspase-8 activation.
Neuroblastoma
Mangiferin prevents the impairment of mitochondrial dynamics and an increase in oxidative stress caused by excessive fluoride in SH-SY5Y cells.
Neuroblastoma
PEST-containing nuclear protein mediates the proliferation, migration, and invasion of human neuroblastoma cells through MAPK and PI3K/AKT/mTOR signaling pathways.
Neuroblastoma
Pre-processed caspase-9 contained in mitochondria participates in apoptosis.
Neuroblastoma
The effect of caspase-9 in the differentiation of SH-SY5Y cells.
Neuroblastoma
The N-myc paradox: N-myc overexpression in neuroblastomas is associated with sensitivity as well as resistance to apoptosis.
Neuroblastoma
The potential tumour suppressor role for caspase-9 (CASP9) in the childhood malignancy, neuroblastoma.
Neuroblastoma
The role of caspases 9 and 9-short (9S) in death ligand- and drug-induced apoptosis in human astrocytoma cells.
Neurodegenerative Diseases
Caspase-9.
Neurofibromatoses
MicroRNA-373 promotes the development of esophageal squamous cell carcinoma by targeting LATS2 and OXR1.
Neurofibromatosis 2
MicroRNA-373 promotes the development of esophageal squamous cell carcinoma by targeting LATS2 and OXR1.
Neuroinflammatory Diseases
Neuroprotective effect of curcumin on okadaic acid induced memory impairment in mice.
Non-alcoholic Fatty Liver Disease
Caspase 3, 6, 8, and 9 Gene Expression in Peripheral Blood Leukocytes and Plasma Concentrations of IL-6 and TNF-? in Carriers of Different Polymorphic Marker -174G>C Genotypes of IL6 Gene Associated with the Risk of Nonalcoholic Steatohepatitis.
Non-alcoholic Fatty Liver Disease
Effects of 4-nonylphenol on oxidant/antioxidant balance system inducing hepatic steatosis in male rat.
Non-alcoholic Fatty Liver Disease
[Effects of three Wenyang Jianpi Tang on cell proliferation and apoptosis of nonalcoholic fatty liver cells].
Obesity
The coexistence of nocturnal sustained hypoxia and obesity additively increases cardiac apoptosis.
Obesity
[Soluble apoptosis markers in obese patients with food intolerance].
Oligospermia
Caspase signalling pathways in human spermatogenesis.
Opisthorchiasis
Effect of curcumin on pathogenesis of hamster-opisthorchiasis through apoptosis-related gene expression.
Optic Atrophy
Antiapoptotic and mitochondrial biogenetic effects of exercise training on ovariectomized hypertensive rat hearts.
Optic Atrophy, Autosomal Dominant
Arsenic-induced cardiotoxicity correlates with mitochondrial damage and trace elements imbalance in broiler chickens.
Osteoarthritis
ATF6 upregulates XBP1S and inhibits ER stress-mediated apoptosis in osteoarthritis cartilage.
Osteoarthritis, Knee
[Effects of inner-heating acupuncture on apoptosis of chondrocytes and expression of Caspase-3 and Caspase-9 in rats with knee osteoarthritis].
Osteoporosis
Simvastatin protects human osteosarcoma cells from oxidative stress-induced apoptosis through mitochondrial-mediated signaling.
Osteosarcoma
Actein Inhibits Cell Proliferation and Migration in Human Osteosarcoma.
Osteosarcoma
Aluminium blunts the proliferative response and increases apoptosis of cultured human cells: putative relationship to alzheimer's disease.
Osteosarcoma
Betulin inhibits mTOR and induces autophagy to promote apoptosis in human osteosarcoma cell lines.
Osteosarcoma
ClC-5 Downregulation Induces Osteosarcoma Cell Apoptosis by Promoting Bax and tBid Complex Formation.
Osteosarcoma
Downregulation of microRNA-95-3p suppresses cell growth of osteosarcoma via CDKN1A/p21 expression.
Osteosarcoma
LncRNA SNHG20 knockdown suppresses the osteosarcoma tumorigenesis through the mitochondrial apoptosis pathway by miR-139/RUNX2 axis.
Osteosarcoma
MicroRNA-34a inhibits tumor invasion and metastasis in osteosarcoma partly by effecting C-IAP2 and Bcl-2.
Osteosarcoma
Plumbagin induces apoptosis via the p53 pathway and generation of reactive oxygen species in human osteosarcoma cells.
Osteosarcoma
Triptolide induces the cell apoptosis of osteosarcoma cells through the TRAIL pathway.
Osteosarcoma
Zinc promotes cell apoptosis via activating the Wnt-3a/?-catenin signaling pathway in osteosarcoma.
Ototoxicity
Hwanggunchungyitang prevents cadmium-induced ototoxicity through suppression of the activation of caspase-9 and extracellular signal-related kinase in auditory HEI-OC1 cells.
Ovarian Neoplasms
(-)-Asarinin from the Roots of Asarum sieboldii Induces Apoptotic Cell Death via Caspase Activation in Human Ovarian Cancer Cells.
Ovarian Neoplasms
Antiproliferative and apoptotic activities of tosylcyclonovobiocic acids as potent heat shock protein 90 inhibitors in human cancer cells.
Ovarian Neoplasms
Berbamine suppresses cell proliferation and promotes apoptosis in ovarian cancer partially via the inhibition of Wnt/?-catenin signaling.
Ovarian Neoplasms
Bik/NBK accumulation correlates with apoptosis-induction by bortezomib (PS-341, Velcade) and other proteasome inhibitors.
Ovarian Neoplasms
Caspase 9 is required for p53-dependent apoptosis and chemosensitivity in a human ovarian cancer cell line.
Ovarian Neoplasms
Costunolide Inhibits the Growth of OAW42-A Multidrug-Resistant Human Ovarian Cancer Cells by Activating Apoptotic and Autophagic Pathways, Production of Reactive Oxygen Species (ROS), Cleaved Caspase-3 and Cleaved Caspase-9.
Ovarian Neoplasms
Dysfunctional apoptosome activation in ovarian cancer: implications for chemoresistance.
Ovarian Neoplasms
Effect of Amino Acids on the Generation of Ginsenoside Rg3 Epimers by Heat Processing and the Anticancer Activities of Epimers in A2780 Human Ovarian Cancer Cells.
Ovarian Neoplasms
Effect of small interfering RNA transfection on FAK and DLC1 mRNA expression in OVCAR-3.
Ovarian Neoplasms
Enhancement of cisplatin-induced apoptosis by ?-elemene in resistant human ovarian cancer cells.
Ovarian Neoplasms
Evaluation of the Potential Diagnostic Utility of the Determination of Selected Caspases-Markers Involved in the Regulation of Apoptosis-In Patients with Ovarian Cancer.
Ovarian Neoplasms
Impact of the histone deacetylase inhibitor trichostatin A on active uptake, volume-sensitive release of taurine, and cell fate in human ovarian cancer cells.
Ovarian Neoplasms
MAPT (Tau) expression is a biomarker for an increased rate of survival in pediatric neuroblastoma.
Ovarian Neoplasms
Phosphorylation of caspase-9 at Thr125 directs paclitaxel resistance in ovarian cancer.
Ovarian Neoplasms
Polyphyllin I inhibits the growth of ovarian cancer cells in nude mice.
Ovarian Neoplasms
Potentiation of paclitaxel-induced apoptosis by the novel cyclin-dependent kinase inhibitor NU6140: a possible role for survivin down-regulation.
Ovarian Neoplasms
Preclinical activity of the liposomal cisplatin lipoplatin in ovarian cancer.
Ovarian Neoplasms
Suppressing effects of daily oral supplementation of beta-glucan extracted from Agaricus blazei Murill on spontaneous and peritoneal disseminated metastasis in mouse model.
Ovarian Neoplasms
Targeting Ovarian Cancer and Chemoresistance Through Selective Inhibition of Sphingosine Kinase-2 with ABC294640.
Ovarian Neoplasms
Trichostatin a restores apaf-1 function in chemoresistant ovarian cancer cells.
Ovarian Neoplasms
Trichostatin A sensitizes human ovarian cancer cells to TRAIL-induced apoptosis by down-regulation of c-FLIPL via inhibition of EGFR pathway.
palmitoyl[protein] hydrolase deficiency
Palmitoyl-protein thioesterase-1 deficiency leads to the activation of caspase-9 and contributes to rapid neurodegeneration in INCL.
Pancreatic Neoplasms
Apoptosis and anergy of T cell induced by pancreatic stellate cells-derived galectin-1 in pancreatic cancer.
Pancreatic Neoplasms
Effects of Caspase-9 and Survivin Gene Polymorphisms in Pancreatic Cancer Risk and Tumor Characteristics.
Pancreatic Neoplasms
Inhibition of RIP and c-FLIP enhances TRAIL-induced apoptosis in pancreatic cancer cells.
Pancreatic Neoplasms
The mitochondrion interfering compound NPC-26 exerts potent anti-pancreatic cancer cell activity in vitro and in vivo.
Pancreatic Neoplasms
The Orexin-A-Regulated Akt/mTOR Pathway Promotes Cell Proliferation Through Inhibiting Apoptosis in Pancreatic Cancer Cells.
Pancreatic Neoplasms
TRAIL and triptolide: an effective combination that induces apoptosis in pancreatic cancer cells.
Pancreatitis
Caspase-9 acts as a regulator of necroptotic cell death.
Pancreatitis
Effects of emodin on intestinal mucosal barrier by the upregulation of miR-218a-5p expression in rats with acute necrotizing pancreatitis.
Pancreatitis
Genetic Susceptibility in Acute Pancreatitis: Genotyping of GSTM1, GSTT1, GSTP1, CASP7, CASP8, CASP9, CASP10, LTA, TNFRSF1B, and TP53 Gene Variants.
Papilledema
Endothelial activation of caspase-9 promotes neurovascular injury in retinal vein occlusion.
Papilloma
A synthetic coumarin (4-Methyl-7 hydroxy coumarin) has anti-cancer potentials against DMBA-induced skin cancer in mice.
Papilloma
Activation of P2X(7)-mediated apoptosis Inhibits DMBA/TPA-induced formation of skin papillomas and cancer in mice.
Paracoccidioidomycosis
Altered ex vivo expression of caspase 8, caspase 9 and Bcl-2 is associated with the T-cell hyporreactivity of paracoccidioidomycosis patients.
Paralysis
Dysequilibrium between caspases and their inhibitors in a mouse model for amyotrophic lateral sclerosis.
Parasitic Diseases
Fas/CD95-mediated apoptosis of type II cells is blocked by Toxoplasma gondii primarily via interference with the mitochondrial amplification loop.
Parkinson Disease
A protective role for N-acylphosphatidylethanolamine phospholipase D in 6-OHDA-induced neurodegeneration.
Parkinson Disease
A tetracycline-regulated adenovirus encoding dominant-negative caspase-9 is regulated in rat brain and protects against neurotoxin-induced cell death in vitro, but not in vivo.
Parkinson Disease
Caspase-9 activation results in downstream caspase-8 activation and bid cleavage in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease.
Parkinson Disease
Overexpression of alpha-synuclein in rat substantia nigra results in loss of dopaminergic neurons, phosphorylation of alpha-synuclein and activation of caspase-9: resemblance to pathogenetic changes in Parkinson's disease.
Parkinson Disease
Progressive degeneration of dopamine neurons in 6-hydroxydopamine rat model of Parkinson's disease does not involve activation of caspase-9 and caspase-3.
Perinatal Death
Raf Kinases Are Essential for Phosphate Induction of ERK1/2 Phosphorylation in Hypertrophic Chondrocytes and Normal Endochondral Bone Development.
Periodontal Diseases
Immune response mediated by Th1 / IL-17 / caspase-9 promotes evolution of periodontal disease.
Periodontal Diseases
The role of caspase-8, caspase-9, and apoptosis inducing factor in periodontal disease.
Periodontitis
Porphyromonas gingivalis Differentially Modulates Apoptosome Apoptotic Peptidase Activating Factor 1 in Epithelial Cells and Fibroblasts.
Periodontitis
Regulation of Anti-Apoptotic SOD2 and BIRC3 in Periodontal Cells and Tissues.
Persistent Infection
Increased expressions of ADAMTS-13 and apoptosis contribute to neuropathology during Toxoplasma gondii encephalitis in mice.
Pheochromocytoma
Caspase-3-dependent proteolytic cleavage of protein kinase Cdelta is essential for oxidative stress-mediated dopaminergic cell death after exposure to methylcyclopentadienyl manganese tricarbonyl.
Pheochromocytoma
Phosphorylation-dependent Akt cleavage in neural cell in vitro reconstitution of apoptosis.
Pneumonia
Suppression of alveolar macrophage apoptosis prolongs survival of rats and mice with pneumocystis pneumonia.
Pneumonia, Pneumocystis
Caspase-9 as a target for Pneumocystis pneumonia therapy.
Polycystic Kidney, Autosomal Dominant
Pathways of caspase-mediated apoptosis in autosomal-dominant polycystic kidney disease (ADPKD).
Pre-Eclampsia
Effect of hypoxia on expression of placental trophoblast cells SATB1 and ?-catenin and its correlation with the pathogenesis of preeclampsia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Purification and characterization of a cytotoxic neurotoxin-like protein from Naja haje haje venom that induces mitochondrial apoptosis pathway.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Resveratrol induces extensive apoptosis by depolarizing mitochondrial membranes and activating caspase-9 in acute lymphoblastic leukemia cells.
Primary Myelofibrosis
Dysregulation of the intrinsic apoptotic pathway mediates megakaryocytic hyperplasia in myeloproliferative neoplasms.
Prostatic Neoplasms
A novel dietary triterpene Lupeol induces fas-mediated apoptotic death of androgen-sensitive prostate cancer cells and inhibits tumor growth in a xenograft model.
Prostatic Neoplasms
A novel histone deacetylase inhibitor, CG200745, potentiates anticancer effect of docetaxel in prostate cancer via decreasing Mcl-1 and Bcl-(XL).
Prostatic Neoplasms
Anti-cancer effect of ursolic acid activates apoptosis through ROCK/PTEN mediated mitochondrial translocation of cofilin-1 in prostate cancer.
Prostatic Neoplasms
Apoptotic activity and mechanism of 2-cyano-3,12-dioxoolean-1,9-dien-28-oic-acid and related synthetic triterpenoids in prostate cancer.
Prostatic Neoplasms
Auraptene Induces Apoptosis via Myeloid Cell Leukemia 1-Mediated Activation of Caspases in PC3 and DU145 Prostate Cancer Cells.
Prostatic Neoplasms
Bcl-2 family inhibition sensitizes human prostate cancer cells to docetaxel and promotes unexpected apoptosis under caspase-9 inhibition.
Prostatic Neoplasms
Characterisation of a Tip60 specific inhibitor, NU9056, in prostate cancer.
Prostatic Neoplasms
Dentatin Induces Apoptosis in Prostate Cancer Cells via Bcl-2, Bcl-xL, Survivin Downregulation, Caspase-9, -3/7 Activation, and NF-?B Inhibition.
Prostatic Neoplasms
Development, Optimization and Evaluation of 2-Methoxy-Estradiol Loaded Nanocarrier for Prostate Cancer.
Prostatic Neoplasms
Dietary isothiocyanate mediated apoptosis of human cancer cells is associated with Bcl-xL phosphorylation.
Prostatic Neoplasms
Discovery of embelin as a cell-permeable, small-molecular weight inhibitor of XIAP through structure-based computational screening of a traditional herbal medicine three-dimensional structure database.
Prostatic Neoplasms
Effect of laminin tyrosine-isoleucine-glycine-serine-arginine peptide on the growth of human prostate cancer (PC-3) cells in vitro.
Prostatic Neoplasms
Effects of Caspase 9 Gene Polymorphism in Patients with Prostate Cancer.
Prostatic Neoplasms
Emetine regulates the alternative splicing of caspase 9 in tumor cells.
Prostatic Neoplasms
EMP1 regulates caspase-9 and VEGFC expression and suppresses prostate cancer cell proliferation and invasion.
Prostatic Neoplasms
Enhanced therapeutic effect of cisplatin on the prostate cancer in tumor-bearing mice by transfecting the attenuated Salmonella carrying a plasmid co-expressing p53 gene and mdm2 siRNA.
Prostatic Neoplasms
Estrogen receptor ? upregulates FOXO3a and causes induction of apoptosis through PUMA in prostate cancer.
Prostatic Neoplasms
Expression analysis of caspase-6, caspase-9 and BNIP3 in prostate cancer.
Prostatic Neoplasms
HAX-1 inhibits apoptosis in prostate cancer through the suppression of caspase-9 activation.
Prostatic Neoplasms
Induction of endoplasmic reticulum stress and apoptosis by a marine prostanoid in human hepatocellular carcinoma.
Prostatic Neoplasms
Influence of caspases 8 and 9 gene promoter polymorphism on prostate cancer susceptibility and early development of hormone refractory prostate cancer.
Prostatic Neoplasms
Inorganic selenium sensitizes prostate cancer cells to TRAIL-induced apoptosis through superoxide/p53/Bax-mediated activation of mitochondrial pathway.
Prostatic Neoplasms
Isoliquiritigenin induces apoptosis by depolarizing mitochondrial membranes in prostate cancer cells.
Prostatic Neoplasms
Knockdown of zinc finger protein X-linked inhibits prostate cancer cell proliferation and induces apoptosis by activating caspase-3 and caspase-9.
Prostatic Neoplasms
LncRNA PVT1 predicts prognosis and regulates tumor growth in prostate cancer.
Prostatic Neoplasms
LncRNA UNC5B-AS1 promotes malignant progression of prostate cancer by competitive binding to caspase-9.
Prostatic Neoplasms
Loss of caspase-1 and caspase-3 protein expression in human prostate cancer.
Prostatic Neoplasms
microRNA-323 upregulation promotes prostate cancer growth and docetaxel resistance by repressing p73.
Prostatic Neoplasms
Molecular mechanisms of resveratrol (3,4,5-trihydroxy-trans-stilbene) and its interaction with TNF-related apoptosis inducing ligand (TRAIL) in androgen-insensitive prostate cancer cells.
Prostatic Neoplasms
PIM-1-specific mAb suppresses human and mouse tumor growth by decreasing PIM-1 levels, reducing Akt phosphorylation, and activating apoptosis.
Prostatic Neoplasms
SGO1 induces proliferation and metastasis of prostate cancer through AKT-mediated signaling pathway.
Prostatic Neoplasms
Sildenafil increases chemotherapeutic efficacy of doxorubicin in prostate cancer and ameliorates cardiac dysfunction.
Prostatic Neoplasms
Thapsigargin induces a calmodulin/calcineurin-dependent apoptotic cascade responsible for the death of prostatic cancer cells.
Prostatic Neoplasms
[Sanggenon C induces apoptosis of prostate cancer PC3 cells by activating caspase 3 and caspase 9 pathways].
Pulmonary Disease, Chronic Obstructive
The role of bronchial epithelial cell apoptosis in the pathogenesis of COPD.
Pulmonary Edema
MicroRNA-146a overexpression alleviates intestinal ischemia/reperfusion-induced acute lung injury in mice.
Pulmonary Fibrosis
Restoring microRNA-499-5p Protects Sepsis-Induced Lung Injury Mice Via Targeting Sox6.
Pulmonary Fibrosis
[Effects of curcumin on apoptosis of pulmonary fibroblasts from rats]
Radicular Cyst
Effect of calcium hydroxide as intracanal medicament on the expression of caspase-9 located within the radicular cyst epithelium.
Rectal Neoplasms
Association between main Caspase gene polymorphisms and the susceptibility and prognosis of colorectal cancer.
Reperfusion Injury
Interaction between XIAP and Smac/DIABLO in the mouse brain after transient focal cerebral ischemia.
Reperfusion Injury
MiR-484 Protects Rat Myocardial Cells from Ischemia-Reperfusion Injury by Inhibiting Caspase-3 and Caspase-9 during Apoptosis.
Reperfusion Injury
Rapamycin prevents cerebral stroke by modulating apoptosis and autophagy in penumbra in rats.
Retinal Degeneration
Light Induces Ultrastructural Changes in Rod Outer and Inner Segments, Including Autophagy, in a Transgenic Xenopus laevis P23H Rhodopsin Model of Retinitis Pigmentosa.
Retinal Detachment
FAS-mediated apoptosis and its relation to intrinsic pathway activation in an experimental model of retinal detachment.
Retinal Detachment
Inhibition of Retinal Detachment-induced Apoptosis in Photoreceptors by a Small Peptide Inhibitor of the Fas Receptor.
Retinal Vein Occlusion
Author Correction: Endothelial activation of caspase-9 promotes neurovascular injury in retinal vein occlusion.
Retinal Vein Occlusion
Endothelial activation of caspase-9 promotes neurovascular injury in retinal vein occlusion.
Retinoblastoma
cAMP-response element-binding protein mediates acid-induced NADPH oxidase NOX5-S expression in Barrett esophageal adenocarcinoma cells.
Retinoblastoma
d-3-Deoxy-dioctanoylphosphatidylinositol induces cytotoxicity in human MCF-7 breast cancer cells via a mechanism that involves downregulation of the D-type cyclin-retinoblastoma pathway.
Retinoblastoma
In vitro and in vivo effects and mechanisms of celecoxib-induced growth inhibition of human hepatocellular carcinoma cells.
Retinoblastoma
Luteolin induces apoptosis in oral squamous cancer cells.
Rhabdomyosarcoma
Apoptosis of stomach cancer cell SGC-7901 and regulation of Akt signaling way induced by bovine lactoferrin.
Salmonella Infections
Characterization of Salmonella-induced cell death in human macrophage-like THP-1 cells.
Sarcoma
IFN regulatory factor 8 sensitizes soft tissue sarcoma cells to death receptor-initiated apoptosis via repression of FLICE-like protein expression.
Sarcoma 180
Antitumorpharmacological mechanism of the oral liquid of Poriacocos polysaccharide.
Sarcoma, Ewing
miR-185 suppresses progression of Ewing's sarcoma via inhibiting the PI3K/AKT and Wnt/?-catenin pathways.
Sarcoma, Kaposi
Cancer gene therapy with iCaspase-9 transcriptionally targeted to tumor endothelial cells.
Sarcopenia
Elevated caspase and AIF gene expression correlate with progression of sarcopenia during aging in male F344BN rats.
Seizures
2R,4R-APDC, a Metabotropic Glutamate Receptor Agonist, Reduced Neuronal Apoptosis by Upregulating MicroRNA-128 in a Rat Model After Seizures.
Seizures
Activation of the caspase 8 pathway mediates seizure-induced cell death in cultured hippocampal neurons.
Seizures
Bcl-2 and Caspase-9 serum levels in children and adolescents with idiopathic epilepsy and active seizures.
Seizures
Cortical expression of IL1-?, Bcl-2, Caspase-3 and 9, SEMA-3a, NT-3 and P-glycoprotein as biological markers of intrinsic severity in drug-resistant temporal lobe epilepsy.
Seizures
Do hyperbaric oxygen-induced seizures cause brain damage?
Seizures
Ferulic acid ameliorates pentylenetetrazol-induced seizures by reducing neuron cell death.
Seizures
Formation of the Apaf-1/cytochrome c complex precedes activation of caspase-9 during seizure-induced neuronal death.
Seizures
[The expression of Smac and XIAP in rat hippocampus following limbic seizure induced by kainic acid injection into amygdaloid nucleus]
Sepsis
Delayed neutrophil apoptosis in sepsis is associated with maintenance of mitochondrial transmembrane potential and reduced caspase-9 activity.
Sepsis
Local thymic caspase-9 inhibition improves survival during polymicrobial sepsis in mice.
Sepsis
Role of Exogenous Hsp72 on Liver Dysfunction during Sepsis.
Sepsis
Survivin and caspases serum protein levels and survivin variants mRNA expression in sepsis.
Sleep Initiation and Maintenance Disorders
Integrative analysis of genome-wide association study and brain region related enhancer maps identifies biological pathways for insomnia.
Spinal Cord Compression
[Effects of decompression combined with electro-acupuncture on rat with acute severe upper cervical spinal cord compression injury].
Spinal Cord Injuries
Effects of combined and individual use of N-methyl-D aspartate receptor antagonist magnesium sulphate and caspase-9 inhibitor z-LEDH-fmk in experimental spinal cord injury.
Spinal Cord Injuries
Neuroprotection and functional recovery after application of the caspase-9 inhibitor z-LEHD-fmk in a rat model of traumatic spinal cord injury.
Spinal Cord Injuries
Neuroprotection of netrin-1 on neurological recovery via Wnt/?-catenin signaling pathway after spinal cord injury.
Spinal Cord Injuries
Upregulation of miR-199a-5p Protects Spinal Cord Against Ischemia/Reperfusion-Induced Injury via Downregulation of ECE1 in Rat.
Spinal Dysraphism
Apoptosis, Expression of PAX3 and P53, and Caspase Signal in Fetuses with Neural Tube Defects.
Squamous Cell Carcinoma of Head and Neck
Cancer gene therapy with iCaspase-9 transcriptionally targeted to tumor endothelial cells.
Squamous Cell Carcinoma of Head and Neck
CASP9 c.-1339A>G and CASP3 c.-1191A>G polymorphisms alter susceptibility and clinical aspects of head and neck squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Caspase-9 regulates cisplatin-induced apoptosis in human head and neck squamous cell carcinoma cells.
Squamous Cell Carcinoma of Head and Neck
Effect of ethanol extracts of Antrodia cinnamomea on head and neck squamous cell carcinoma cell line.
Squamous Cell Carcinoma of Head and Neck
GSTP1 c.313A>G, XPD c.934G>A, XPF c.2505T>C and CASP9 c.-1339A>G Polymorphisms and Severity of Vomiting in Head and Neck Cancer Patients treated with Cisplatin Chemoradiation.
Squamous Cell Carcinoma of Head and Neck
Histone deacetylase inhibitor suberoylanilide hydroxamic acid induces apoptosis through both mitochondrial and Fas (Cd95) signaling in head and neck squamous carcinoma cells.
Squamous Cell Carcinoma of Head and Neck
Influence of CASP9 c.-1339A>G and CASP3 c.-1191A>G variants in outcome of patients with head and neck squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Inhibition of caspase-9 activity and Apaf-1 expression in cisplatin-resistant head and neck squamous cell carcinoma cells.
Squamous Cell Carcinoma of Head and Neck
Sam68 reduces cisplatin-induced apoptosis in tongue carcinoma.
Squamous Cell Carcinoma of Head and Neck
The proteasome inhibitor MG132 potentiates TRAIL receptor agonist-induced apoptosis by stabilizing tBid and Bik in human head and neck squamous cell carcinoma cells.
Squamous Cell Carcinoma of Head and Neck
[Effects of salinomycin on proliferation and apoptosis of oral squamous cell carcinoma].
Squamous Cell Carcinoma of Head and Neck
[Inhibition of caspase-9 activity in cisplatin-resistant head and neck squamous cell carcinoma]
Starvation
Canavanine augments proapoptotic effects of arginine deprivation in cultured human cancer cells.
Starvation
Distinct biological activities of C3 and ADP-ribosyltransferase-deficient C3-E174Q.
Starvation
Hepatitis B virus X protein reduces starvation-induced cell death through activation of autophagy and inhibition of mitochondrial apoptotic pathway.
Starvation
HIV protease inhibitors provide neuroprotection through inhibition of mitochondrial apoptosis in mice.
Starvation
Multiple death pathways in retina-derived 661W cells following growth factor deprivation: crosstalk between caspases and calpains.
Starvation
Neuropeptide Y enhances proliferation and prevents apoptosis in rat bone marrow stromal cells in association with activation of the Wnt/?-catenin pathway in vitro.
Starvation
Non-suckling starvation of neonatal mice promotes primordial follicle formation with activation of ovarian autophagy.
Status Epilepticus
Caspase-dependent programmed cell death pathways are not activated in generalized seizure-induced neuronal death.
Status Epilepticus
[Effect of recombinant human erythropoietin on hippocampal p-Akt and caspase-9 expressions in rats with status epilepticus and the mechanism]
Stomach Neoplasms
Adenovirus-directed expression of TIPE2 suppresses gastric cancer growth via induction of apoptosis and inhibition of AKT and ERK1/2 signaling.
Stomach Neoplasms
Anti-gastric cancer effects of celecoxib, a selective COX-2 inhibitor, through inhibition of Akt signaling.
Stomach Neoplasms
Antitumor activity of ginsenoside Rd in gastric cancer via up-regulation of Caspase-3 and Caspase-9.
Stomach Neoplasms
Baicalin extracted from Huangqin (Radix Scutellariae Baicalensis) induces apoptosis in gastric cancer cells by regulating B cell lymphoma
(Bcl-2)/Bcl-2-associated X protein and activating caspase-3 and caspase-9.
Stomach Neoplasms
Caspase 8 and caspase 9 gene polymorphisms and susceptibility to gastric cancer.
Stomach Neoplasms
Danthron, an anthraquinone derivative, induces DNA damage and caspase cascades-mediated apoptosis in SNU-1 human gastric cancer cells through mitochondrial permeability transition pores and Bax-triggered pathways.
Stomach Neoplasms
Deguelin promotes apoptosis and inhibits angiogenesis of gastric cancer.
Stomach Neoplasms
Downregulation of AKT and MDM2, Melatonin Induces Apoptosis in AGS and MGC803 Cells.
Stomach Neoplasms
Dysregulated Expression of Apoptosis-Associated Genes and MicroRNAs and Their Involvement in Gastric Carcinogenesis.
Stomach Neoplasms
Effects of celecoxib on cycle kinetics of gastric cancer cells and protein expression of cytochrome C and caspase-9.
Stomach Neoplasms
Esculetin exerts antitumor effect on human gastric cancer cells through IGF-1/PI3K/Akt signaling pathway.
Stomach Neoplasms
Esculetin induces apoptosis in human gastric cancer cells through a cyclophilin D-mediated mitochondrial permeability transition pore associated with ROS.
Stomach Neoplasms
Exogenous morphine inhibits human gastric cancer MGC- 803 cell growth by cell cycle arrest and apoptosis induction.
Stomach Neoplasms
Identification of an alternative form of caspase-9 in human gastric cancer cell lines: a role of a caspase-9 variant in apoptosis resistance.
Stomach Neoplasms
Immune clearance gastric carcinoma cells in ascites by activating caspase-9-induced apoptosis.
Stomach Neoplasms
In vivo and in vitro inhibition of human gastric cancer progress by upregulating Kank1 gene.
Stomach Neoplasms
miR-877-5p antagonizes the promoting effect of SP on the gastric cancer progression.
Stomach Neoplasms
NAIF1 is down-regulated in gastric cancer and promotes apoptosis through the caspase-9 pathway in human MKN45 cells.
Stomach Neoplasms
Oridonin, a novel lysine acetyltransferases inhibitor, inhibits proliferation and induces apoptosis in gastric cancer cells through p53- and caspase-3-mediated mechanisms.
Stomach Neoplasms
Prognostic significance of mRNA expression of CASPs in gastric cancer.
Stomach Neoplasms
Reovirus infection induces apoptosis of TRAIL-resistant gastric cancer cells by down-regulation of Akt activation.
Stomach Neoplasms
RP11-874J12.4, a novel lncRNA, confers chemoresistance in human gastric cancer cells by sponging miR-3972 and upregulating SSR2 expression.
Stomach Neoplasms
The effect of aloe-emodin-induced photodynamic activity on the apoptosis of human gastric cancer cells: A pilot study.
Stomach Neoplasms
Thymoquinone inhibits growth and augments 5-fluorouracil-induced apoptosis in gastric cancer cells both in vitro and in vivo.
Stomach Neoplasms
Ultrafine particles of Ulmus davidiana var. japonica induce apoptosis of gastric cancer cells via activation of caspase and endoplasmic reticulum stress.
Stomach Neoplasms
Ursolic acid promotes apoptosis of SGC-7901 gastric cancer cells through ROCK/PTEN mediated mitochondrial translocation of cofilin-1.
Stomach Neoplasms
[Association of CASP3 and CASP9 polymorphisms with genetic susceptibility to stomach cancer].
Stomach Neoplasms
[Changes in the number of copies of genetic loci in gastric cancer].
Stomach Neoplasms
[Chinese herbal medicine Euphorbia esula extract induces apoptosis and inhibits the proliferation, migration and invasion of multidrug resistant gastric carcinoma cells].
Stomach Neoplasms
[Effect of Ferula ferulaeoides on growth and apoptosis of human gastric cancer MGC-803 transplantation tumor in nude mice].
Stomach Neoplasms
[Effects of betulinic acid on apoptosis of human gastric cancer MGC-803 cells].
Stomach Neoplasms
[Expressions of gastrin and apoptosis-associated proteins involved in mitochondrial pathway in gastric cancer tissues and the clinical significance].
Stomach Neoplasms
[Study on apoptosis of human stomach SGC-7901 cells induced by extracts of Solanum lyratum]
Stomach Neoplasms
[Toosendanin induces apoptosis of human gastric cancer MGC-803 cells and its mechanism].
Stroke
Association Between a Polymorphism in CASP3 and CASP9 Genes and Ischemic Stroke.
Stroke
Intranasal delivery of caspase-9 inhibitor reduces caspase-6-dependent axon/neuron loss and improves neurological function after stroke.
Testicular Neoplasms
Failure of activation of caspase-9 induces a higher threshold for apoptosis and cisplatin resistance in testicular cancer.
Thrombocythemia, Essential
Effects of polymorphic DNA genes involved in BER and caspase pathways on the clinical outcome of myeloproliferative neoplasms under treatment with hydroxyurea.
Thrombocythemia, Essential
The Role of Caspase Genes Polymorphisms in Genetic Susceptibility to Philadelphia-Negative Myeloproliferative Neoplasms in a Portuguese Population.
Thrombocytopenia
Caspase-9 mediates the apoptotic death of megakaryocytes and platelets, but is dispensable for their generation and function.
Thrombocytosis
Dysregulation of the intrinsic apoptotic pathway mediates megakaryocytic hyperplasia in myeloproliferative neoplasms.
Thrombosis
Breaking symmetry in protein dimers: designs and functions.
Thymoma
Cell quality control mechanisms maintain stemness and differentiation potential of P19 embryonic carcinoma cells.
Thymoma
Cypermethrin Alters the Expression Profile of mRNAs in the Adult Rat Striatum: A Putative Mechanism of Postnatal Pre-exposure Followed by Adulthood Re-exposure-Enhanced Neurodegeneration.
Thymoma
Expression of c-Jun, p73, Casp9, and N-ras in thymic epithelial tumors: relationship with the current WHO classification systems.
Thymoma
Relationship of possible biomarkers with malignancy of thymic tumors: a meta-analysis.
Thyroid Cancer, Papillary
Role of Caspase 8, Caspase 9 and Bcl-2 polymorphisms in papillary thyroid carcinoma risk in Han Chinese population.
Thyroid Carcinoma, Anaplastic
Cytochrome c release is upstream to activation of caspase-9, caspase-8, and caspase-3 in the enhanced apoptosis of anaplastic thyroid cancer cells induced by manumycin and paclitaxel.
Thyroid Neoplasms
Anti-proliferative and anti-invasive effects of ferulic acid in TT medullary thyroid cancer cells interacting with URG4/URGCP.
Thyroid Neoplasms
CXCR4/RhoA signaling pathway is involved in miR-128-regulated proliferation and apoptosis of human thyroid cancer cells.
Thyroid Neoplasms
Long non-coding RNA LINC00607 silencing exerts antioncogenic effects on thyroid cancer through the CASP9 Promoter methylation.
Thyroid Neoplasms
Proteomic expression profiling of thyroid neoplasms.
Tongue Neoplasms
Emodin induces apoptosis of human tongue squamous cancer SCC-4 cells through reactive oxygen species and mitochondria-dependent pathways.
Tricuspid Valve Insufficiency
Mitochondrial apoptotic pathway activation in the atria of heart failure patients due to mitral and tricuspid regurgitation.
Triple Negative Breast Neoplasms
Comparative proteomic profiling of triple-negative breast cancer reveals that up-regulation of RhoGDI-2 is associated to the inhibition of caspase 3 and caspase 9.
Triple Negative Breast Neoplasms
LncRNA POU3F3 promotes proliferation and inhibits apoptosis of cancer cells in triple-negative breast cancer by inactivating caspase 9.
Triple Negative Breast Neoplasms
MicroRNA-224 Promotes Tumorigenesis through Downregulation of Caspase-9 in Triple-Negative Breast Cancer.
Triple Negative Breast Neoplasms
Targeted inhibition of Notch1 gene enhances the killing effects of paclitaxel on triple negative breast cancer cells.
Triple Negative Breast Neoplasms
The analog of cGAMP, c-di-AMP, activates STING mediated cell death pathway in estrogen-receptor negative breast cancer cells.
Tuberculosis
Bim is a crucial regulator of apoptosis induced by Mycobacterium tuberculosis.
Tuberculosis
Involvement of caspase-9 in the inhibition of necrosis of RAW 264 cells infected with Mycobacterium tuberculosis.
Tuberculosis
Monocytes from tuberculosis patients that exhibit cleaved caspase 9 and denaturalized cytochrome c are more susceptible to death mediated by Toll-like receptor 2.
Urinary Bladder Neoplasms
Baicalein induces apoptosis via a mitochondrial-dependent caspase activation pathway in T24 bladder cancer cells.
Urinary Bladder Neoplasms
Brucea javanica oil induces apoptosis in T24 bladder cancer cells via upregulation of caspase-3, caspase-9, and inhibition of NF-kappaB and COX-2 expressions.
Urinary Bladder Neoplasms
Caspase 9 and Caspase 8 Gene Polymorphisms and Susceptibility to Bladder Cancer in North Indian Population.
Urinary Bladder Neoplasms
Diindolylmethane and Lupeol Modulates Apoptosis and Cell Proliferation in N-Butyl-N-(4-Hydroxybutyl) Nitrosamine Initiated and Dimethylarsinic Acid Promoted rat Bladder Carcinogenesis.
Urinary Bladder Neoplasms
Gene expression study related with the intrinsic pathway of apoptosis in bladder cancer by real-time PCR technique.
Urinary Bladder Neoplasms
Heptaphylline suppresses the proliferation and migration of human bladder cancer cells via induction of intrinsic apoptosis, autophagy and inhibition of ?-catenin signalling pathway.
Urinary Bladder Neoplasms
Mitochondria are the primary target in isothiocyanate-induced apoptosis in human bladder cancer cells.
Urinary Bladder Neoplasms
Potential therapeutic effects of N-butylidenephthalide from Radix Angelica Sinensis (Danggui) in human bladder cancer cells.
Uterine Cervical Neoplasms
Anti-Condyloma acuminata mechanism of microRNAs-375 modulates HPV in cervical cancer cells via the UBE3A and IGF-1R pathway.
Uterine Cervical Neoplasms
Beclin 1-mediated macroautophagy involves regulation of caspase-9 expression in cervical cancer HeLa cells.
Uterine Cervical Neoplasms
Emodin induces apoptosis of human cervical cancer cells through poly(ADP-ribose) polymerase cleavage and activation of caspase-9.
Uterine Cervical Neoplasms
Inhibition of ADP-ribosylation factor-like 6 interacting protein 1 suppresses proliferation and reduces tumor cell invasion in CaSki human cervical cancer cells.
Uterine Cervical Neoplasms
Realgar-induced apoptosis of cervical cancer cell line Siha via cytochrome C release and caspase-3 and caspase-9 activation.
Uterine Cervical Neoplasms
Synergistic anticancer activity of dietary tea polyphenols and bleomycin hydrochloride in human cervical cancer cell: Caspase-dependent and independent apoptotic pathways.
Uterine Cervical Neoplasms
Tafazzin (TAZ) promotes the tumorigenicity of cervical cancer cells and inhibits apoptosis.
Vaccinia
Deletion of the viral anti-apoptotic gene F1L in the HIV/AIDS vaccine candidate MVA-C enhances immune responses against HIV-1 antigens.
Vaccinia
Extracts from rabbit skin inflamed by the vaccinia virus attenuate bupivacaine-induced spinal neurotoxicity in pregnant rats.
Vaccinia
Structural Determinants of Caspase-9 Inhibition by the Vaccinia Virus Protein, F1L.
Vaccinia
Vaccinia virus protein F1L is a caspase-9 inhibitor.
Varicocele
Dysregulated apoptosis through the intrinsic pathway in the internal spermatic vein of patients with varicocele.
Varicocele
Sperm caspase-9 in oligoasthenoteratozoospermic men with and without varicocele.
Varicose Veins
Dysregulated apoptosis in primary varicose veins.
Ventricular Dysfunction, Left
Activation of caspase-3 may not contribute to postresuscitation myocardial dysfunction.
Ventricular Fibrillation
Targeting mitochondria for resuscitation from cardiac arrest.
Vertigo
CASP9 genotype confers gentamicin susceptibility in intratympanic treatment of intractable vertigo caused by Ménière's disease.
Vesicular Stomatitis
Alpha/beta interferons potentiate virus-induced apoptosis through activation of the FADD/Caspase-8 death signaling pathway.
Virus Diseases
Approaches to the removal of T-lymphocytes to minimize graft-versus-host disease in patients with primary immunodeficiencies who do not have a matched sibling donor.
Virus Diseases
Flavivirus activates phosphatidylinositol 3-kinase signaling to block caspase-dependent apoptotic cell death at the early stage of virus infection.
Virus Diseases
Tioman virus infection in experimentally infected mouse brain and its association with apoptosis.
Virus Diseases
Variability in apoptotic response to poliovirus infection.
Virus Diseases
[Antagonism of baicalin on cell cyclical distribution and cell apoptosis in A549 cells infected with influenza A (H1N1) virus].
Whooping Cough
Butyrate and propionate induced activated or non-activated neutrophil apoptosis via HDAC inhibitor activity but without activating GPR-41/GPR-43 pathways.
Whooping Cough
LPA protects intestinal epithelial cells from apoptosis by inhibiting the mitochondrial pathway.
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3.4.22.62 caspase-9
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The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable). 
