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Disease on EC 3.4.22.58 - caspase-5

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Arthritis, Rheumatoid
The association between caspase-5 gene polymorphisms and rheumatoid arthritis in a Chinese population.
Asthma
Elevated expression of the NLRP3 inflammasome in neutrophilic asthma.
Breast Neoplasms
Mutational analysis of caspase 1, 4, and 5 genes in common human cancers.
Carcinogenesis
Mutational analysis of caspase 1, 4, and 5 genes in common human cancers.
Carcinoma
Mutational analysis of caspase 1, 4, and 5 genes in common human cancers.
TGF-betaRII, BAX, IGFIIR, caspase-5, hMSH3 and hMSH6 alterations are not associated with microsatellite instability or p53 mutations in invasive urothelial carcinoma of the urinary bladder.
Cholera
Single-cell imaging of inflammatory caspase dimerization reveals differential recruitment to inflammasomes.
Colorectal Neoplasms
BAX and caspase-5 frameshift mutations and spontaneous apoptosis in colorectal cancer with microsatellite instability.
Mutational analysis of caspase 1, 4, and 5 genes in common human cancers.
Cowpox
Caspase-4 and caspase-5, members of the ICE/CED-3 family of cysteine proteases, are CrmA-inhibitable proteases.
Endometrial Neoplasms
Analysis of candidate target genes for mononucleotide repeat mutation in microsatellite instability-high (MSI-H) endometrial cancer.
Gastrointestinal Neoplasms
Frameshift mutations at mononucleotide repeats in caspase-5 and other target genes in endometrial and gastrointestinal cancer of the microsatellite mutator phenotype.
Infections
Caspase-11 promotes the fusion of phagosomes harboring pathogenic bacteria with lysosomes by modulating actin polymerization.
Development of an ex vivo Tissue Platform to Study the Human Lung Response to Coxiella burnetii.
Leishmania infantum infection reduces the amyloid ?42-stimulated NLRP3 inflammasome activation.
NLRP3 inflammasome activation downstream of cytoplasmic LPS recognition by both caspase-4 and caspase-5.
SERPINB1-mediated checkpoint of inflammatory caspase activation.
Leukemia
Frameshift mutations in caspase-5 and other target genes in leukemia and lymphoma cell lines having microsatellite instability.
Lung Neoplasms
Somatic mutation of the Caspase-5 gene in human lung cancer.
Lymphoma
Frameshift mutations in caspase-5 and other target genes in leukemia and lymphoma cell lines having microsatellite instability.
Macular Degeneration
Distinct CD40L receptors mediate inflammasome activation and secretion of IL-1? and MCP-1 in cultured human retinal pigment epithelial cells.
Neoplasm Metastasis
Somatic mutation of the Caspase-5 gene in human lung cancer.
Neoplasms
Association of Caspases with an Increased Prostate Cancer Risk in North Indian Population.
BAX and caspase-5 frameshift mutations and spontaneous apoptosis in colorectal cancer with microsatellite instability.
Cytogenetic aberrations and heterogeneity of mutations in repeat-containing genes in a colon carcinoma from a patient with hereditary nonpolyposis colorectal cancer.
Defective DNA-mismatch repair: a potential mediator of leukemogenic susceptibility in therapy-related myelodysplasia and leukemia.
Effects of elevated ammonium on the transcriptome of stony coral Pocillopora damicornis.
Expressional changes of genes and miRNA in common megakaryocyte-erythroid progenitors from lower-risk myelodysplastic syndrome.
Flow cytometry analysis of apoptotic progression and expression analysis of four apoptosis-related genes in Penaeus vannamei in response to white spot syndrome virus infection.
Frameshift mutations at mononucleotide repeats in caspase-5 and other target genes in endometrial and gastrointestinal cancer of the microsatellite mutator phenotype.
Identification of biomarkers predicting the chemotherapeutic outcomes of capecitabine and oxaliplatin in patients with gastric cancer.
Indication of participation of caspase-2 and caspase-5 in mechanisms of human cervical malignancy.
Microsatellite mutations of transforming growth factor-beta receptor type II and caspase-5 occur in human precursor T-cell lymphoblastic lymphomas/leukemias in vivo but are not associated with hMSH2 or hMLH1 promoter methylation.
Mutational analysis of caspase 1, 4, and 5 genes in common human cancers.
Repeated sequences in CASPASE-5 and FANCD2 but not NF1 are targets for mutation in microsatellite-unstable acute leukemia/myelodysplastic syndrome.
Somatic mutation of the Caspase-5 gene in human lung cancer.
Osteosarcoma
MiR-218 promotes apoptosis of U2OS osteosarcoma cells through targeting BIRC5.
Psoriasis
Association of angiopoietin-1, angiopoietin-2 and caspase-5 polymorphisms with psoriasis vulgaris.
Caspase-5 expression is upregulated in lesional psoriatic skin.
Th17 micro-milieu regulates NLRP1-dependent caspase-5 activity in skin autoinflammation.
Retinoblastoma
Functional complementation studies identify candidate genes and common genetic variants associated with ovarian cancer survival.
Salmonella Infections
NLRP3 inflammasome activation downstream of cytoplasmic LPS recognition by both caspase-4 and caspase-5.
Sarcoma
Copper Induces Apoptosis of Neuroblastoma Cells Via Post-translational Regulation of the Expression of Bcl-2-family Proteins and the tx Mouse is a Better Model of Hepatic than Brain Cu Toxicity.
Sepsis
Complement pathway amplifies caspase-11-dependent cell death and endotoxin-induced sepsis severity.
Skin Diseases
Caspase-5 expression is upregulated in lesional psoriatic skin.
Urinary Bladder Neoplasms
TGF-betaRII, BAX, IGFIIR, caspase-5, hMSH3 and hMSH6 alterations are not associated with microsatellite instability or p53 mutations in invasive urothelial carcinoma of the urinary bladder.