Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

BRENDA Home
show all | hide all No of entries

Information on EC 3.4.22.55 - caspase-2 and Organism(s) Gallus gallus and UniProt Accession Q98943

for references in articles please use BRENDA:EC3.4.22.55
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.22 Cysteine endopeptidases
                3.4.22.55 caspase-2
Specify your search results
Select one or more organisms in this record: ?
This record set is specific for:
Gallus gallus
UNIPROT: Q98943 not found.
Show additional data
Do not include text mining results
Include (text mining) results
Include results (AMENDA + additional results, but less precise)
Word Map
The taxonomic range for the selected organisms is: Gallus gallus
The enzyme appears in selected viruses and cellular organisms
Reaction Schemes
strict requirement for an Asp residue at P1, with Asp316 being essential for proteolytic activity and has a preferred cleavage sequence of Val-Asp-Val-Ala-Asp-/-
Synonyms
caspase-2, caspase 2, casp2, ich-1, casp-2, caspase-2l, nedd-2, caspase-2s, ajcasp, ich-1 protease, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
C14.006
-
-
-
-
CASP-2
-
-
-
-
caspase 2
-
-
-
-
ICH-1 protease
-
-
-
-
ICH-1L/1S
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
hydrolysis of peptide bond
-
-
-
-
CAS REGISTRY NUMBER
COMMENTARY hide
182372-14-1
-
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
z-VDVAD-fmk
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
SwissProt
Manually annotated by BRENDA team
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
CASP2_CHICK
424
0
47960
Swiss-Prot
other Location (Reliability: 5)
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Johnson, A.L.; Bridgham, J.T.; Bergeron, L.; Yuan, J.
Characterization of the avian Ich-1 cDNA and expression of Ich-1L mRNA in the hen ovary
Gene
192
227-233
1997
Gallus gallus (Q98943), Gallus gallus
Manually annotated by BRENDA team
Kong, J.Y.; Rabkin, S.W.
Cytoskeletal actin degradation induced by lovastatin in cardiomyocytes is mediated through caspase-2
Cell Biol. Int.
28
781-790
2004
Gallus gallus (Q98943)
Manually annotated by BRENDA team