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Disease on EC 3.4.21.B7 - mannan-binding lectin-associated serine protease 1

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Angioedemas, Hereditary
The Levels of the Lectin Pathway Serine Protease MASP-1 and Its Complex Formation with C1 Inhibitor Are Linked to the Severity of Hereditary Angioedema.
Arthritis
Essential role of complement mannose-binding lectin-associated serine proteases-1/3 in the murine collagen antibody-induced model of inflammatory arthritis.
Key Components of the Complement Lectin Pathway Are Not Only Required for the Development of Inflammatory Arthritis but Also Regulate the Transcription of Factor D.
Mannan-Binding Lectin-Associated Serine Protease 1/3 Cleavage of Pro-Factor D into Factor D In Vivo and Attenuation of Collagen Antibody-Induced Arthritis through Their Targeted Inhibition by RNA Interference-Mediated Gene Silencing.
Atherosclerosis
Distinct Longitudinal Associations of MBL, MASP-1, MASP-2, MASP-3, and MAp44 With Endothelial Dysfunction and Intima-Media Thickness: The Cohort on Diabetes and Atherosclerosis Maastricht (CODAM) Study.
Autoimmune Diseases
Circulating levels of mannan-binding lectin (MBL) and MBL-associated serine protease 2 in endemic pemphigus foliaceus.
Bacterial Infections
Cutting Edge: A New Player in the Alternative Complement Pathway, MASP-1 Is Essential for LPS-Induced, but Not for Zymosan-Induced, Alternative Pathway Activation.
Functional characterization of a ficolin-mediated complement pathway in amphioxus.
Mannan-binding lectin-associated serine protease-1 (MASP-1) mediates immune responses against Aeromonas hydrophila in vitro and in vivo in grass carp.
Blindness
Proteomics-based identification and validation of novel plasma biomarkers phospholipid transfer protein and mannan-binding lectin serine protease-1 in age-related macular degeneration.
Brain Injuries
Mannan binding lectin-associated serine protease-2 (MASP-2) critically contributes to post-ischemic brain injury independent of MASP-1.
Brain Ischemia
Mannan binding lectin-associated serine protease-2 (MASP-2) critically contributes to post-ischemic brain injury independent of MASP-1.
Carcinoma
Identification of novel candidate target genes, including EPHB3, MASP1 and SST at 3q26.2-q29 in squamous cell carcinoma of the lung.
Carcinoma, Squamous Cell
Identification of novel candidate target genes, including EPHB3, MASP1 and SST at 3q26.2-q29 in squamous cell carcinoma of the lung.
Cardiovascular Diseases
MASPs at the crossroad between the complement and the coagulation cascades - the case for COVID-19.
Cerebrovascular Disorders
MASPs at the crossroad between the complement and the coagulation cascades - the case for COVID-19.
Cervical Intraepithelial Neoplasia
MASP-1 and MASP-2 Serum Levels Are Associated With Worse Prognostic in Cervical Cancer Progression.
COVID-19
MASPs at the crossroad between the complement and the coagulation cascades - the case for COVID-19.
Crohn Disease
Polymorphisms in the Mannose-Binding Lectin Gene are Associated with Defective Mannose-Binding Lectin Functional Activity in Crohn's Disease Patients.
Diabetes Mellitus
Plasma Levels of MASP-1 and MASP-2 are Elevated in Type 1 Diabetes and Correlate with Glycaemic Control.
Diabetes Mellitus, Type 1
Plasma Levels of MASP-1 and MASP-2 are Elevated in Type 1 Diabetes and Correlate with Glycaemic Control.
Diabetes Mellitus, Type 2
MASP1, THBS1, GPLD1 and ApoA-IV are novel biomarkers associated with prediabetes: the KORA F4 study.
Plasma levels of MASP-1, MASP-3 and MAp44 in patients with type 2 diabetes - influence of glycaemic control, body composition and polymorphisms in the MASP1 gene.
Glioma
Dibutyryl cAMP- or Interleukin-6-induced astrocytic differentiation enhances mannose binding lectin (MBL)-associated serine protease (MASP)-1/3 expression in C6 glioma cells.
Expression of H-ficolin/Hakata antigen, mannose-binding lectin-associated serine protease (MASP)-1 and MASP-3 by human glioma cell line T98G.
Glomerulonephritis
Glomerular deposition of mannose-binding lectin (MBL) indicates a novel mechanism of complement activation in IgA nephropathy.
Heart Arrest
The complement lectin pathway after cardiac arrest.
Hepatitis C
Mannan binding lectin-associated serine protease 1 is induced by hepatitis C virus infection and activates human hepatic stellate cells.
Hyperglycemia
Comprehensive transcriptome analysis of colorectal cancer risk of hyperglycemia in humans.
Hypertension
MASPs at the crossroad between the complement and the coagulation cascades - the case for COVID-19.
Infections
Circulating levels of mannan-binding lectin (MBL) and MBL-associated serine protease 2 in endemic pemphigus foliaceus.
Cleavage of kininogen and subsequent bradykinin release by the complement component: mannose-binding lectin-associated serine protease (MASP)-1.
Mannan binding lectin-associated serine protease 1 is induced by hepatitis C virus infection and activates human hepatic stellate cells.
MASP-1 Increases Endothelial Permeability.
Ischemic Stroke
Serine proteases of the complement lectin pathway and their genetic variations in ischaemic stroke.
Leprosy
Adding MASP1 to the lectin pathway-Leprosy association puzzle: Hints from gene polymorphisms and protein levels.
Liver Cirrhosis
Mannan binding lectin-associated serine protease 1 is induced by hepatitis C virus infection and activates human hepatic stellate cells.
Liver Diseases
Mannan binding lectin-associated serine protease 1 is induced by hepatitis C virus infection and activates human hepatic stellate cells.
Lupus Erythematosus, Systemic
Mesangial IgA2 deposits and lectin pathway-mediated complement activation in IgA glomerulonephritis.
The lectin complement pathway serine proteases (MASPs) represent a possible crossroad between the coagulation and complement systems in thromboinflammation.
Macular Degeneration
Proteomics-based identification and validation of novel plasma biomarkers phospholipid transfer protein and mannan-binding lectin serine protease-1 in age-related macular degeneration.
Mastitis
Polymorphisms of mannose-binding lectin-associated serine protease 1 (MASP1) and its relationship with milk performance traits and complement activity in Chinese Holstein cattle.
Meningitis, Pneumococcal
Mannose-binding lectin-associated serine protease 2 (MASP-2) contributes to poor disease outcome in humans and mice with pneumococcal meningitis.
Mucocutaneous Lymph Node Syndrome
Plasma MASP-1 concentration and its relationship to recovery from coronary artery lesion in children with Kawasaki disease.
Myocardial Infarction
Association between endogenous complement inhibitor and myocardial salvage in patients with myocardial infarction.
Neoplasms
Comprehensive Identification of the Human Secretome as Potential Indicators in Treatment Outcome of HPV-Positive and -Negative Cervical Cancer Patients.
Mannose-Binding Lectin (MBL) and MBL-associated serine protease-2 (MASP-2) in women with malignant and benign ovarian tumours.
MASP-1 and MASP-2 Serum Levels Are Associated With Worse Prognostic in Cervical Cancer Progression.
Ovarian Neoplasms
Mannose-Binding Lectin (MBL) and MBL-associated serine protease-2 (MASP-2) in women with malignant and benign ovarian tumours.
Peptic Ulcer
Protective effect and mechanisms of action of Mongolian medicine Sulongga-4 on pyloric ligation-induced gastroduodenal ulcer in rats.
Pre-Eclampsia
Polymorphisms in complement genes and risk of preeclampsia in Taiyuan, China.
Prediabetic State
MASP1, THBS1, GPLD1 and ApoA-IV are novel biomarkers associated with prediabetes: the KORA F4 study.
Proteinuria
Clinical Value of Complement Activation Biomarkers in Overt Diabetic Nephropathy.
Pulmonary Disease, Chronic Obstructive
MASPs at the crossroad between the complement and the coagulation cascades - the case for COVID-19.
Renal Insufficiency, Chronic
MASPs at the crossroad between the complement and the coagulation cascades - the case for COVID-19.
Sepsis
MASP-1 of the complement system alters fibrinolytic behaviour of blood clots.
Reduced Mannose-Binding Lectin-Associated Serine Protease (MASP)-1 is Associated with Disturbed Coagulation in Septic Shock.
Shock, Septic
Reduced Mannose-Binding Lectin-Associated Serine Protease (MASP)-1 is Associated with Disturbed Coagulation in Septic Shock.
Stroke
Plasma levels of mannan-binding lectin (MBL)-associated serine proteases (MASPs) and MBL-associated protein in cardio- and cerebrovascular diseases.
Serine proteases of the complement lectin pathway and their genetic variations in ischaemic stroke.
Thrombosis
Mannose-binding lectin-associated serine protease-1 is a significant contributor to coagulation in a murine model of occlusive thrombosis.
MASP-1 of the complement system alters fibrinolytic behaviour of blood clots.
Plasma levels of mannan-binding lectin (MBL)-associated serine proteases (MASPs) and MBL-associated protein in cardio- and cerebrovascular diseases.
Targeted sequencing to identify novel genetic risk factors for deep vein thrombosis: a study of 734 genes.
Uterine Cervical Neoplasms
Comprehensive Identification of the Human Secretome as Potential Indicators in Treatment Outcome of HPV-Positive and -Negative Cervical Cancer Patients.
MASP-1 and MASP-2 Serum Levels Are Associated With Worse Prognostic in Cervical Cancer Progression.