Information on EC 3.4.21.73 - u-Plasminogen activator

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The expected taxonomic range for this enzyme is: Opisthokonta

EC NUMBER
COMMENTARY
3.4.21.73
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RECOMMENDED NAME
GeneOntology No.
u-Plasminogen activator
REACTION
REACTION DIAGRAM
COMMENTARY
ORGANISM
UNIPROT ACCESSION NO.
LITERATURE
Specific cleavage of Arg-/-Val bond in plasminogen to form plasmin
show the reaction diagram
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REACTION TYPE
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
hydrolysis of peptide bond
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SYNONYMS
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
Abbokinase
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Cellular plasminogen activator
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Double-chain urokinase-type plasminogen activator
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EC 3.4.21.31
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formerly
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EC 3.4.99.26
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formerly
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Plasminogen activator, urokinase-type
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PLAU
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Two-chain urokinase-type plasminogen activator
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u-PA
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U-plasminogen activator
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uPA
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uPA
P00749
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uPA
Mus musculus C57BL/6J
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uPA-type Plg activator
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Urinary esterase A
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Urinary plasminogen activator
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Urokinase
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Urokinase plasminogen activator
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Urokinase plasminogen activator
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Urokinase plasminogen activator
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urokinase type plasminogen activator
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urokinase-plasminogen activator
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urokinase-type PA
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urokinase-type PA
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urokinase-type plasmin activator
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urokinase-type plasminogen
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Urokinase-type plasminogen activator
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Urokinase-type plasminogen activator
P00749
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Urokinase-type plasminogen activator
Mus musculus C57BL/6J
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Urokinase-type plasminogen activator
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urokinase-type Plg activator
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urokine-type plasminogen activator
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CAS REGISTRY NUMBER
COMMENTARY
139639-24-0
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ORGANISM
COMMENTARY
LITERATURE
SEQUENCE CODE
SEQUENCE DB
SOURCE
Calbiochem
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Manually annotated by BRENDA team
commercial preparation from Sigma Aldrich
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Manually annotated by BRENDA team
commercial preparation of low-molecular weight uPA from American Diagnostica
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Manually annotated by BRENDA team
from Sandoz, Nürnberg
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Manually annotated by BRENDA team
high-molecular weight uPA expressed in SP2/0 cell culture from Abbott Biotech; low-molecular weight uPA, Abbokinase, from Abbott Labs, North Chicago
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Manually annotated by BRENDA team
nonphosphorylated and phosphorylated on serine
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Manually annotated by BRENDA team
patients with acute and chronic hepatitis B
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Manually annotated by BRENDA team
patients with allergic asthma
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Manually annotated by BRENDA team
patients with colorectal cancer
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Manually annotated by BRENDA team
patients with common variable immunodeficiency
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Manually annotated by BRENDA team
patients with Quebec platelet disease
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Manually annotated by BRENDA team
recombinant 54000 MW scuPA, plasmin-resistant rscuPA with Lys158 mutagenized to Glu and a 32000 MW form of rscuPA consisting of Leu144-Leu411 are obtained by expression of cDNA in Chinese hamster ovary cells
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Manually annotated by BRENDA team
recombinant amino-terminal fragment S1-E143 expressed in Pichia pastoris
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Manually annotated by BRENDA team
recombinant plasmin-resistant mutant of single-chain uPA obtained by site-specific mutagenesis of Lys158 to Glu
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Manually annotated by BRENDA team
recombinant single chain urokinase-type plasminogen activator is home-made by expression of uPA cDNA in Chinese hamster ovary cells
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Manually annotated by BRENDA team
single chain form
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Manually annotated by BRENDA team
single-chain uPA
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Manually annotated by BRENDA team
uPA from Serono and low-molecular weight uPa from Le Petit
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Manually annotated by BRENDA team
commercial preparation of low-molecular weight uPA from American Diagnostica
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Manually annotated by BRENDA team
high-molecular weight uPA expressed in SP2/0 cell culture from Abbott Biotech; low-molecular weight uPA, Abbokinase, from Abbott Labs, North Chicago
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Manually annotated by BRENDA team
recombinant 54000 MW scuPA, plasmin-resistant rscuPA with Lys158 mutagenized to Glu and a 32000 MW form of rscuPA consisting of Leu144-Leu411 are obtained by expression of cDNA in Chinese hamster ovary cells
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Manually annotated by BRENDA team
recombinant single chain urokinase-type plasminogen activator is home-made by expression of uPA cDNA in Chinese hamster ovary cells
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Manually annotated by BRENDA team
uPA from Serono and low-molecular weight uPa from Le Petit
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Manually annotated by BRENDA team
C57BL/6J mice
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Manually annotated by BRENDA team
mice model for kidney ischemia reperfusion injury and for acute kidney allograft rejection
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Manually annotated by BRENDA team
Mus musculus C57BL/6J
C57BL/6J mice
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Manually annotated by BRENDA team
piglets
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Manually annotated by BRENDA team
PDB
SCOP
CATH
ORGANISM