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Reference on EC 3.4.21.7 - plasmin

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Robbins, K.; Summaria, L.; Wohl, R.C.
Human plasmin
Methods Enzymol.
80
379-387
1981
Homo sapiens
Manually annotated by BRENDA team
Robbins, K.C.; Summaria, L.
Plasminogen and plasmin
Methods Enzymol.
45
257-273
1976
Oryctolagus cuniculus, Homo sapiens
Manually annotated by BRENDA team
Castellino, F.J.
A unique enzyme - protein substrate modifier reaction: plasmin/streptokinase interaction
Trends Biochem. Sci.
4
1-5
1979
Homo sapiens
-
Manually annotated by BRENDA team
Castellino, F.J.; Sodetz, J.M.
Rabbit plasminogen and plasmin isozymes
Methods Enzymol.
45
273-286
1976
Oryctolagus cuniculus
Manually annotated by BRENDA team
Sodetz, J.M.; Violand, B.N.; Castellino, F.J.
A kinetic characterization of the rabbit plasmin isozymes
Arch. Biochem. Biophys.
174
209-215
1976
Oryctolagus cuniculus
Manually annotated by BRENDA team
Robbins, K.C.; Summaria, L.
Human plasminogen and plasmin
Methods Enzymol.
19
184-199
1970
Homo sapiens
-
Manually annotated by BRENDA team
Greig, H.B.W.; Cornelius, E.M.
Protamine-heparin complex as substrate for plasmin
Biochim. Biophys. Acta
67
658-668
1963
Homo sapiens
Manually annotated by BRENDA team
Benfeldt, C.; Larsen, L.B.; Rasmussen, J.T.; Andreasen, P.A.; Petersen, T.E.
Isolation and characterization of plasminogen and plasmin from bovine milk
Int. Dairy J.
5
577-592
1995
Bos taurus
Manually annotated by BRENDA team
Kolev, K.; Lerant, I.; Tenekejiev, K.; Machovich, R.
Regulation of fibrinolytic activity of neutrophil leukocyte elastase, plasmin, and miniplasmin by plasma protease inhibitors
J. Biol. Chem.
269
17030-17034
1994
Homo sapiens
Manually annotated by BRENDA team
Osterwalder, T.; Cinelli, P.; Baici, A.; Pennella, A.; Krueger, S.R.; Schrimpf, S.P.; Meins, M.; Sonderegger, P.
The axonally secreted serine proteinase inhibitor, neuroserpin, inhibits plasminogen activators and plasmin but not thrombin
J. Biol. Chem.
273
2312-2321
1998
Sus scrofa
Manually annotated by BRENDA team
Bastian, E.D.; Hansen, K.G.; Brown, R.J.
Inhibition of plasmin by beta-lactoglobulin using casein and a synthetic substrate
J. Dairy Sci.
76
3354-3361
1993
Bos taurus
Manually annotated by BRENDA team
Wang, X.; Lin, X.; Loy, J.A.; Tang, J.; Zhang, X.C.
Crystal structure of the catalytic structure of the catalytic domain of human plasmin complexed with streptokinase
Science
281
1662-1665
1998
Homo sapiens
Manually annotated by BRENDA team
Higazi, A.A.R.; Mayer, M.
Inhibition of plasmin by fibrinogen
Biochem. J.
269
299-302
1990
Homo sapiens
Manually annotated by BRENDA team
Mhashilkar, A.M.; Viswanatha, T.; Chibber, B.A.K.; Castellino, F.J.
Breaching the conformational integrity of the catalytic triad of the serine protease plasmin: localized disruption of a side chain of His-603 strongly inhibits the amidolytic activity of human plasmin
Proc. Natl. Acad. Sci. USA
90
5374-5377
1993
Homo sapiens
Manually annotated by BRENDA team
Sazonova, I.Y.; Aisina, R.B.; Muhametova, L.I.; Varfolomeyev, S.D.
Kinetic properties of the activator complexes plasmin-staphylokinase and plasmin(ogen)-streptokinase in vitro
Biochemistry
64
66-74
1999
Homo sapiens
Manually annotated by BRENDA team
Rickli, E.E.; Otavsky, W.I.
A new method of isolation and some properties of the heavy chain of human plasmin
Eur. J. Biochem.
59
441-447
1975
Homo sapiens
Manually annotated by BRENDA team
Lijnen, H.R.; van Hoef, B.; Smith, R.A.G.; Collen, D.
Functional properties of p-anisoylated plasmin-staphylokinase complex
Thromb. Haemost.
70
326-331
1993
Homo sapiens
Manually annotated by BRENDA team
Longchamp, S.; Randriamahazaka, H.N.; Nigretto, J.M.
Electrochemical assay and properties of plasmin adsorbed onto a carbon paste electrode
J. Electroanal. Chem.
412
31-37
1996
Homo sapiens
-
Manually annotated by BRENDA team
Fitzpatrick, S.L.; Kassam, G.; Choi, K.S.; Kang, H.M.; Fogg, D.K.; Waisman, D.M.
Regulation of plasmin activity by annexin II tetramer
Biochemistry
39
1021-1028
2000
Homo sapiens
Manually annotated by BRENDA team
Mitsudo, K.; Jayakumar, A.; Henderson, Y.; Frederick, M.J.; Kang, Y.; Wang, M.; El-Naggar, A.K.; Clayman, G.L.
Inhibition of serine proteinases plasmin, trypsin, subtilisin A, cathepsin G, and elastase by LEKTI: a kinetic analysis
Biochemistry
42
3874-3881
2003
Homo sapiens
Manually annotated by BRENDA team
Brown, E.W.; Ravindran, S.; Patston, P.A.
The reaction between plasmin and C1-inhibitor results in plasmin inhibition by the serpin mechanism
Blood Coagul. Fibrinolysis
13
711-714
2002
Homo sapiens
Manually annotated by BRENDA team
Ries, M.; Zenker, M.
Influence of soluble fibrin on reaction kinetics of plasmin type 1 and type 2 with alpha2-antiplasmin
Blood Coagul. Fibrinolysis
14
203-209
2003
Homo sapiens
Manually annotated by BRENDA team
Syrovets, T.; Simmet, T.
Novel aspects and new roles for the serine protease plasmin
Cell. Mol. Life Sci.
61
873-885
2004
Homo sapiens
Manually annotated by BRENDA team
Hervio, L.S.; Coombs, G.S.; Bergstrom, R.C.; Trivedi, K.; Corey, D.R.; Madison, E.L.
Negative selectivity and the evolution of protease cascades: the specificity of plasmin for peptide and protein substrates
Chem. Biol.
7
443-453
2000
Homo sapiens
Manually annotated by BRENDA team
Okada, Y.; Matsumoto, Y.; Tsuda, Y.; Tada, M.; Wanaka, K.; Hijikata-Okunomiya, A.; Okamoto, S.
Development of plasmin-selective inhibitors and studies of their structure-activity relationship
Chem. Pharm. Bull.
48
184-193
2000
Homo sapiens
Manually annotated by BRENDA team
Lauer, G.; Sollberg, S.; Cole, M.; Krieg, T.; Eming, S.A.
Generation of a novel proteolysis resistant vascular endothelial growth factor165 variant by a site-directed mutation at the plasmin sensitive cleavage site
FEBS Lett.
531
309-313
2002
Homo sapiens
Manually annotated by BRENDA team
Zhang, W.Y.; Ishii, I.; Kruth, H.S.
Plasmin-mediated macrophage reversal of low density lipoprotein aggregation
J. Biol. Chem.
275
33176-33183
2000
Homo sapiens
Manually annotated by BRENDA team
Jiang, Q.; Taupenot, L.; Mahata, S.K.; Mahata, M.; O'Connor, D.T.; Miles, L.A.; Parmer, R.J.
Proteolytic cleavage of chromogranin A (CgA) by plasmin. Selective liberation of a specific bioactive CgA fragment that regulates catecholamine release
J. Biol. Chem.
276
25022-25029
2001
Homo sapiens
Manually annotated by BRENDA team
Vakili, J.; Standker, L.; Detheux, M.; Vassart, G.; Forssmann, W.G.; Parmentier, M.
Urokinase plasminogen activator and plasmin efficiently convert hemofiltrate CC chemokine 1 into its active [9-74] processed variant
J. Immunol.
167
3406-3413
2001
Homo sapiens
Manually annotated by BRENDA team
Tucker, H.M.; Kihiko, M.; Caldwell, J.N.; Wright, S.; Kawarabayashi, T.; Price, D.; Walker, D.; Scheff, S.; McGillis, J.P.; Rydel, R.E.; Estus, S.
The plasmin system is induced by and degrades amyloid-beta aggregates
J. Neurosci.
20
3937-3946
2000
Homo sapiens
Manually annotated by BRENDA team
Abato, P.; Yuen, C.M.; Cubanski, J.Y.; Seto, C.T.
Inhibitors of plasmin that extend into both the S and S' binding sites: cooperative interactions between S1 and S2
J. Org. Chem.
67
1184-1191
2002
Homo sapiens
Manually annotated by BRENDA team
Exley, C.; Korchazhkina, O.V.
Plasmin cleaves Abeta42 in vitro and prevents its aggregation into beta-pleated sheet structures
Neuroreport
12
2967-2970
2001
Homo sapiens
Manually annotated by BRENDA team
Midura-Nowaczek, K.; Roszkowska-Jakimiec, W.; Lepietuszko, I.; Bruzgo, I.
Synthesis of benzylamides of dipeptides as potential inhibitors of plasmin
Pharmazie
58
687-689
2003
Homo sapiens
Manually annotated by BRENDA team
Hseu, Y.C.; Chang, W.C.; Yang, H.L.
Inhibition of human plasmin activity using humic acids with arsenic
Sci. Total Environ.
273
93-99
2001
Homo sapiens
Manually annotated by BRENDA team
Yuasa, H.; Tanaka, H.; Hayashi, T.; Wakita, T.; Nakamura, H.; Nishioka, J.; Kawarada, Y.; Suzuki, K.
Bovine protein C inhibitor has a unique reactive site and can transiently inhibit plasmin
Thromb. Haemost.
83
262-267
2000
Bos taurus, Homo sapiens
Manually annotated by BRENDA team
Vrs, G.; Kolev, K.; Csomor, K.; Machovich, R.
Inhibition of plasmin activity by sulfated polyvinylalcohol-acrylate copolymers
Thromb. Res.
100
353-361
2000
Homo sapiens
Manually annotated by BRENDA team
Quagraine, M.O.; Tan, F.; Tamei, H.; Erdoes, E.G.; Skidgel, R.A.
Plasmin alters the activity and quaternary structure of human plasma carboxypeptidase N
Biochem. J.
388
81-91
2005
Homo sapiens
Manually annotated by BRENDA team
Huet, E.; Cauchard, J.H.; Berton, A.; Robinet, A.; Decarme, M.; Hornebeck, W.; Bellon, G.
Inhibition of plasmin-mediated prostromelysin-1 activation by interaction of long chain unsaturated fatty acids with kringle 5
Biochem. Pharmacol.
67
643-654
2004
Homo sapiens
Manually annotated by BRENDA team
Crawley, J.T.; Lam, J.K.; Rance, J.B.; Mollica, L.R.; ODonnell, J.S.; Lane, D.A.
Proteolytic inactivation of ADAMTS13 by thrombin and plasmin
Blood
105
1085-1093
2005
Homo sapiens
Manually annotated by BRENDA team
Diaz, V.M.; Hurtado, M.; Kort, E.J.; Resnati, M.; Blasi, F.; Thomson, T.; Paciucci, R.
Requirement of the enzymatic and signaling activities of plasmin for phorbol-ester-induced scattering of colon cancer cells
Exp. Cell Res.
312
2203-2213
2006
Homo sapiens
Manually annotated by BRENDA team
Bergmann, S.; Rohde, M.; Chhatwal, G.S.; Hammerschmidt, S.
Characterization of plasmin(ogen) binding to Streptococcus pneumoniae
Indian J. Med. Res.
119 Suppl
29-32
2004
Homo sapiens
Manually annotated by BRENDA team
Crudden, A.; Oliveira, J.C.; Kelly, A.L.
Kinetic studies of the thermal inactivation of plasmin in acid or sweet whey
Int. Dairy J.
15
1245-1253
2005
Bos taurus
Manually annotated by BRENDA team
Huppertz, T.; Uniacke, T.; Kelly, A.L.; Fox, P.F.
Inhibition of the proteolytic activity of indigenous plasmin or exogenous chymosin and pepsin in bovine milk by blood serum
Int. dairy J.
16
691-696
2006
Bos taurus
Manually annotated by BRENDA team
Schneider, M.; Brufatto, N.; Neill, E.; Nesheim, M.
Activated thrombin-activatable fibrinolysis inhibitor reduces the ability of high molecular weight fibrin degradation products to protect plasmin from antiplasmin
J. Biol. Chem.
279
13340-13345
2004
Homo sapiens
Manually annotated by BRENDA team
Crudden, A.; Oliveira, J.C.; Kelly, A.L.
Kinetics of changes in plasmin activity and proteolysis on heating milk
J. Dairy Res.
72
493-504
2005
Bos taurus
Manually annotated by BRENDA team
Borda, D.; Indrawati, D.; Smout, C.; Van Loey, A.; Hendrickx, M.
High pressure thermal inactivation kinetics of a plasmin system
J. Dairy Sci.
87
2351-2358
2004
Bos taurus
Manually annotated by BRENDA team
Frohbieter, K.A.; Ismail, B.; Nielsen, S.S.; Hayes, K.D.
Effects of Pseudomonas fluorescens M3/6 bacterial protease on plasmin system and plasminogen activation
J. Dairy Sci.
88
3392-3401
2005
Bos taurus
Manually annotated by BRENDA team
Drinane, M.C.; Sherman, J.A.; Hall, A.E.; Simons, M.; Mulligan-Kehoe, M.J.
Plasminogen and plasmin activity in patients with coronary artery disease
J. Thromb. Haemost.
4
1288-1295
2006
Homo sapiens
Manually annotated by BRENDA team
Nowak, P.; Kolodziejczyk, J.; Wachowicz, B.
Peroxynitrite and fibrinolytic system: the effect of peroxynitrite on plasmin activity
Mol. Cell. Biochem.
267
141-146
2004
Homo sapiens
Manually annotated by BRENDA team
Cosgrove, D.
A complex, tissue-specific role for plasmin and its regulators in modulating fibrogenic activity
Am. J. Physiol.
293
F10-F11
2007
Mus musculus
Manually annotated by BRENDA team
Li, Q.; Laumonnier, Y.; Syrovets, T.; Simmet, T.
Plasmin triggers cytokine induction in human monocyte-derived macrophages
Arterioscler. Thromb. Vasc. Biol.
27
1383-1389
2007
Homo sapiens
Manually annotated by BRENDA team
Fujiyoshi, T.; Hirano, K.; Hirano, M.; Nishimura, J.; Takahashi, S.; Kanaide, H.
Plasmin Induces Endothelium-Dependent Nitric Oxide-Mediated Relaxation in the Porcine Coronary Artery
Arterioscler. Thromb. Vasc. Biol.
27
949-954
2007
Homo sapiens, Sus scrofa
Manually annotated by BRENDA team
Ward, J.R.; Dower, S.K.; Whyte, M.K.; Buttle, D.J.; Sabroe, I.
Potentiation of TLR4 signalling by plasmin activity
Biochem. Biophys. Res. Commun.
341
299-303
2006
synthetic construct
Manually annotated by BRENDA team
Doolittle, R.F.; Pandi, L.
Binding of synthetic B knobs to fibrinogen changes the character of fibrin and inhibits its ability to activate tissue plasminogen activator and its destruction by plasmin
Biochemistry
45
2657-2667
2006
Homo sapiens
Manually annotated by BRENDA team
Schaefer, A.V.; Leslie, B.A.; Rischke, J.A.; Stafford, A.R.; Fredenburgh, J.C.; Weitz, J.I.
Incorporation of fragment X into fibrin clots renders them more susceptible to lysis by plasmin
Biochemistry
45
4257-4265
2006
Homo sapiens
Manually annotated by BRENDA team
Kawao, N.; Okada, K.; Kawata, S.; Okamoto, C.; Tsuritani, M.; Ueshima, S.; Matsuo, O.
Plasmin decreases the BH3-only protein BimEL via the ERK1/2 signaling pathway in hepatocytes
Biochim. Biophys. Acta
1773
718-727
2007
Homo sapiens
Manually annotated by BRENDA team
Nogami, K.; Nishiya, K.; Saenko, E.L.; Takeyama, M.; Tanaka, I.; Yoshioka, A.; Shima, M.
Identification of a plasmin-interactive site within the A2 domain of the factor VIII heavy chain
Biochim. Biophys. Acta
1784
753-763
2008
Homo sapiens
Manually annotated by BRENDA team
Xue, F.; Seto, C.T.
Structure-activity studies of cyclic ketone inhibitors of the serine protease plasmin: design, synthesis, and biological activity
Bioorg. Med. Chem.
14
8467-8487
2006
synthetic construct
Manually annotated by BRENDA team
Nielsen, V.G.
Hydroxyethyl starch enhances fibrinolysis in human plasma by diminishing alpha2-antiplasmin-plasmin interactions
Blood Coagul. Fibrinolysis
18
647-656
2007
Homo sapiens
Manually annotated by BRENDA team
Erbas, H.; Erten, O.; Irfanoglu, M.E.
Breast cyst fluid plasmin activity and its effect on TGF-beta2 activation
Cancer Invest.
26
22-27
2008
Homo sapiens
Manually annotated by BRENDA team
Biswas, N.; Vaingankar, S.M.; Mahata, M.; Das, M.; Gayen, J.R.; Taupenot, L.; Torpey, J.W.; OConnor, D.T.; Mahata, S.K.
Proteolytic cleavage of human chromogranin a containing naturally occurring catestatin variants: differential processing at catestatin region by plasmin
Endocrinology
149
749-757
2008
Homo sapiens
Manually annotated by BRENDA team
Tanka-Salamon, A.; Tenekedjiev, K.; Machovich, R.; Kolev, K.
Suppressed catalytic efficiency of plasmin in the presence of long-chain fatty acids. Identification of kinetic parameters from continuous enzymatic assay with Monte Carlo stimulation
FEBS J.
275
1274-1282
2008
synthetic construct
Manually annotated by BRENDA team
Gray, K.; Ellis, V.
Activation of pro-BDNF by the pericellular serine protease plasmin
FEBS Lett.
582
907-910
2008
Homo sapiens
Manually annotated by BRENDA team
Lei, H.; Velez, G.; Hovland, P.; Hirose, T.; Kazlauskas, A.
Plasmin is the major protease responsible for processing PDGF-C in the vitreous of patients with proliferative vitreoretinopathy
Invest. Ophthalmol. Vis. Sci.
49
42-48
2008
Oryctolagus cuniculus, Homo sapiens
Manually annotated by BRENDA team
Nogami, K.; Shima, M.; Matsumoto, T.; Nishiya, K.; Tanaka, I.; Yoshioka, A.
Mechanisms of plasmin-catalyzed inactivation of factor VIII: a crucial role for proteolytic cleavage at Arg336 responsible for plasmin-catalyzed factor VIII inactivation
J. Biol. Chem.
282
5287-5295
2007
Homo sapiens
Manually annotated by BRENDA team
Zhang, Y.; Zhou, Z.H.; Bugge, T.H.; Wahl, L.M.
Urokinase-type plasminogen activator stimulation of monocyte matrix metalloproteinase-1 production is mediated by plasmin-dependent signaling through annexin A2 and inhibited by inactive plasmin
J. Immunol.
179
3297-3304
2007
Homo sapiens
Manually annotated by BRENDA team
Huang, Y.; Border, W.A.; Lawrence, D.A.; Noble, N.A.
Noninhibitory PAI-1 enhances plasmin-mediated matrix degradation both in vitro and in experimental nephritis
Kidney Int.
70
515-522
2006
Rattus norvegicus
Manually annotated by BRENDA team
Ishida, T.; Tsukada, H.; Hasegawa, T.; Yoshizawa, H.; Gejyo, F.
Matrix metalloproteinase-1 activation via plasmin generated on alveolar epithelial cell surfaces
Lung
184
15-19
2006
Homo sapiens
Manually annotated by BRENDA team
Paczek, L.; Michalska, W.; Bartlomiejczyk, I.
Trypsin, elastase, plasmin and MMP-9 activity in the serum during the human ageing process
Age Ageing
37
318-323
2008
Homo sapiens
Manually annotated by BRENDA team
Ohtsuka, K.; Maekawa, I.; Waki, M.; Takenaka, S.
Electrochemical assay of plasmin activity and its kinetic analysis
Anal. Biochem.
385
293-299
2009
Homo sapiens
Manually annotated by BRENDA team
Brazon, J.; DSuze, G.; DErrico, M.L.; Arocha-Pinango, C.L.; Guerrero, B.
Discreplasminin, a plasmin inhibitor isolated from Tityus discrepans scorpion venom
Arch. Toxicol.
83
669-678
2008
Homo sapiens
Manually annotated by BRENDA team
Guo, Y.; Li, J.; Hagstroem, E.; Ny, T.
Protective effects of plasmin(ogen) in a mouse model of Staphylococcus aureus-induced arthritis
Arthritis Rheum.
58
764-772
2008
Homo sapiens
Manually annotated by BRENDA team
Kamio, N.; Hashizume, H.; Nakao, S.; Matsushima, K.; Sugiya, H.
Plasmin is involved in inflammation via protease-activated receptor-1 activation in human dental pulp
Biochem. Pharmacol.
75
1974-1980
2008
Homo sapiens
Manually annotated by BRENDA team
Tjwa, M.; Janssens, S.; Carmeliet, P.
Plasmin therapy enhances mobilization of HPCs after G-CSF
Blood
112
4048-4050
2008
Mus musculus
Manually annotated by BRENDA team
Flight, S.M.; Johnson, L.A.; Du, Q.S.; Warner, R.L.; Trabi, M.; Gaffney, P.J.; Lavin, M.F.; de Jersey, J.; Masci, P.P.
Textilinin-1, an alternative anti-bleeding agent to aprotinin: Importance of plasmin inhibition in controlling blood loss
Br. J. Haematol.
145
207-211
2009
Mus musculus
Manually annotated by BRENDA team
Hou, Y.; Yang, L.; Mou, M.; Hou, Y.; Zhang, A.; Pan, N.; Qiang, R.; Wei, L.; Zhang, N.
Annexin A2 regulates the levels of plasmin, S100A10 and fascin in L5178Y cells
Cancer Invest.
26
809-815
2008
Mus musculus
Manually annotated by BRENDA team
Potier, A.; Lavigne, C.; Chappard, D.; Verret, J.L.; Chevailler, A.; Nicolie, B.; Drouet, M.
Cutaneous manifestations in Hymenoptera and Diptera anaphylaxis: relationship with basal serum tryptase
Clin. Exp. Allergy
39
717-725
2009
Homo sapiens
Manually annotated by BRENDA team
Heide, R.; van Doorn, K.; Mulder, P.G.; van Toorenenbergen, A.W.; Beishuizen, A.; de Groot, H.; Tank, B.; Oranje, A.P.
Serum tryptase and SCORMA (SCORing MAstocytosis) Index as disease severity parameters in childhood and adult cutaneous mastocytosis
Clin. Exp. Dermatol.
34
462-468
2008
Homo sapiens
Manually annotated by BRENDA team
Hermel, M.; Prenner, J.; Alabdulrazzak, M.; Dailey, W.; Hartzer, M.
Effect of intravitreal plasmin on vitreous removal through a 25-gauge cutting system in the rabbit in vivo
Graefes Arch. Clin. Exp. Ophthalmol.
247
331-334
2009
Homo sapiens
Manually annotated by BRENDA team
Marcinkiewicz, M.; Gordon, P.V.
A role for plasmin in platelet aggregation: differential regulation of IGF release from IGF-IGFBP complexes?
Growth Horm. IGF Res.
18
325-334
2008
Homo sapiens
Manually annotated by BRENDA team
Attali, C.; Durmort, C.; Vernet, T.; Di Guilmi, A.M.
The interaction of Streptococcus pneumoniae with plasmin mediates transmigration across endothelial and epithelial monolayers by intercellular junction cleavage
Infect. Immun.
76
5350-5356
2008
Homo sapiens
Manually annotated by BRENDA team
Kucharewicz, I.; Mogielnicki, A.; Kasacka, I.; Buczko, W.; Bodzenta-?ukaszyk, A.
Plasmin system regulation in an ovalbumin-induced rat model of asthma
Int. Arch. Allergy Immunol.
147
190-196
2008
Rattus norvegicus
Manually annotated by BRENDA team
Bonadonna, P.; Perbellini, O.; Passalacqua, G.; Caruso, B.; Colarossi, S.; Dal Fior, D.; Castellani, L.; Bonetto, C.; Frattini, F.; Dama, A.; Martinelli, G.; Chilosi, M.; Senna, G.; Pizzolo, G.; Zanotti, R.
Clonal mast cell disorders in patients with systemic reactions to Hymenoptera stings and increased serum tryptase levels
J. Allergy Clin. Immunol.
123
680-686
2009
Homo sapiens
Manually annotated by BRENDA team
Mannaioni, G.; Orr, A.G.; Hamill, C.E.; Yuan, H.; Pedone, K.H.; McCoy, K.L.; Berlinguer Palmini, R.; Junge, C.E.; Lee, C.J.; Yepes, M.; Hepler, J.R.; Traynelis, S.F.
Plasmin potentiates synaptic N-methyl-D-aspartate receptor function in hippocampal neurons through activation of protease-activated receptor-1
J. Biol. Chem.
283
20600-20611
2008
Mus musculus
Manually annotated by BRENDA team
Passero, C.J.; Mueller, G.M.; Rondon-Berrios, H.; Tofovic, S.P.; Hughey, R.P.; Kleyman, T.R.
Plasmin activates epithelial Na+ channels by cleaving the gamma subunit
J. Biol. Chem.
283
36586-36591
2008
Bos taurus
Manually annotated by BRENDA team
Yuan, H.; Vance, K.M.; Junge, C.E.; Geballe, M.T.; Snyder, J.P.; Hepler, J.R.; Yepes, M.; Low, C.M.; Traynelis, S.F.
The serine protease plasmin cleaves the amino-terminal domain of the NR2A subunit to relieve zinc inhibition of the N-methyl-D-aspartate receptors
J. Biol. Chem.
284
12862-12873
2009
Homo sapiens
Manually annotated by BRENDA team
Dalsgaard, T.K.; Heegaard, C.W.; Larsen, L.B.
Plasmin digestion of photooxidized milk proteins
J. Dairy Sci.
91
2175-2183
2008
Bos taurus
Manually annotated by BRENDA team
Kothari, H.; Kaur, G.; Sahoo, S.; Idell, S.; Rao, L.V.; Pendurthi, U.
Plasmin enhances cell surface tissue factor activity in mesothelial and endothelial cells
J. Thromb. Haemost.
7
121-131
2009
Homo sapiens
Manually annotated by BRENDA team
Miah, M.F.; Boffa, M.B.
Functional analysis of mutant variants of thrombin-activatable fibrinolysis inhibitor resistant to activation by thrombin or plasmin
J. Thromb. Haemost.
7
665-672
2009
Homo sapiens
Manually annotated by BRENDA team
Zhang, X.; Hoang, E.; Nothnick, W.B.
Estrogen-induced uterine abnormalities in TIMP-1 deficient mice are associated with elevated plasmin activity and reduced expression of the novel uterine plasmin protease inhibitor serpinb7
Mol. Reprod. Dev.
76
160-172
2009
Mus musculus
Manually annotated by BRENDA team
Papanikolaou, T.; Amiridis, G.S.; Dimitriadis, I.; Vainas, E.; Rekkas, C.A.
Effect of plasmin, plasminogen activators and a plasmin inhibitor on bovine in vitro embryo production
Reprod. Fertil. Dev.
20
320-327
2008
Bos taurus
Manually annotated by BRENDA team
Zhi-Liang, W.; Wo-Dong, S.; Min, L.; Xiao-Ping, B.; Jin, J.
Pharmacologic vitreolysis with plasmin and hyaluronidase in diabetic rats
Retina (Philadelphia, Pa.)
29
269-274
2009
Rattus norvegicus
Manually annotated by BRENDA team
Hunt, J.A.; Petteway, S.R.; Scuderi, P.; Novokhatny, V.
Simplified recombinant plasmin: production and functional comparison of a novel thrombolytic molecule with plasma-derived plasmin
Thromb. Haemost.
100
413-419
2008
Homo sapiens
Manually annotated by BRENDA team
Novokhatny, V.
Structure and activity of plasmin and other direct thrombolytic agents
Thromb. Res.
122
S3-S8
2008
Homo sapiens
Manually annotated by BRENDA team
Head, B.P.; Patel, H.H.; Niesman, I.R.; Drummond, J.C.; Roth, D.M.; Patel, P.M.
Inhibition of p75 neurotrophin receptor attenuates isoflurane-mediated neuronal apoptosis in the neonatal central nervous system
Anesthesiology
110
813-825
2009
Mus musculus
Manually annotated by BRENDA team
Nakagawa, H.; Yasuda, S.; Matsuura, E.; Kobayashi, K.; Ieko, M.; Kataoka, H.; Horita, T.; Atsumi, T.; Koike, T.
Nicked beta2-glycoprotein I binds angiostatin 4.5 (plasminogen kringle 1-5) and attenuates its antiangiogenic property
Blood
114
2553-2559
2009
Homo sapiens
Manually annotated by BRENDA team
Maeda, S.; Nakajima, K.; Tohyama, Y.; Kohsaka, S.
Characteristic response of astrocytes to plasminogen/plasmin to upregulate transforming growth factor beta 3 (TGFbeta3) production/secretion through proteinase-activated receptor-1 (PAR-1) and the downstream phosphatidylinositol 3-kinase (PI3K)-Akt/PKB si
Brain Res.
1305
1-13
2009
Rattus norvegicus
Manually annotated by BRENDA team
Gerber, S.S.; Lejon, S.; Locher, M.; Schaller, J.
The human alpha(2)-plasmin inhibitor: functional characterization of the unique plasmin(ogen)-binding region
Cell. Mol. Life Sci.
67
1505-1518
2010
Homo sapiens
Manually annotated by BRENDA team
Millers, E.K.; Trabi, M.; Masci, P.P.; Lavin, M.F.; de Jersey, J.; Guddat, L.W.
Crystal structure of textilinin-1, a Kunitz-type serine protease inhibitor from the venom of the Australian common brown snake (Pseudonaja textilis)
FEBS J.
276
3163-3175
2009
Homo sapiens
Manually annotated by BRENDA team
Koizumi, M.; Momoeda, M.; Hiroi, H.; Nakazawa, F.; Nakae, H.; Ohno, T.; Yano, T.; Taketani, Y.
Inhibition of proteases involved in embryo implantation by cholesterol sulfate
Hum. Reprod.
25
192-197
2010
Homo sapiens
Manually annotated by BRENDA team
Pedroja, B.S.; Kang, L.E.; Imas, A.O.; Carmeliet, P.; Bernstein, A.M.
Plasminogen activator inhibitor-1 regulates integrin alphavbeta3 expression and autocrine transforming growth factor beta signaling
J. Biol. Chem.
284
20708-20717
2009
Mus musculus
Manually annotated by BRENDA team
Sun, Z.; Lu, W.; Jiang, A.; Chen, J.; Tang, F.; Liu, J.N.
Expression, purification and characterization of aprotinin and a human analogue of aprotinin
Protein Expr. Purif.
65
238-243
2009
Homo sapiens
Manually annotated by BRENDA team
Christensen, B.; Schack, L.; Klaening, E.; Sorensen, E.S.
Osteopontin is cleaved at multiple sites close to its integrin-binding motifs in milk and is a novel substrate for plasmin and cathepsin D
J. Biol. Chem.
285
7929-7937
2010
Homo sapiens
Manually annotated by BRENDA team
Sulniute, R.; Lindh, T.; Wilczynska, M.; Li, J.; Ny, T.
Plasmin is essential in preventing periodontitis in mice
Am. J. Pathol.
179
819-828
2011
Mus musculus
Manually annotated by BRENDA team
Li, X.; Syrovets, T.; Genze, F.; Pitterle, K.; Oberhuber, A.; Orend, K.H.; Simmet, T.
Plasmin triggers chemotaxis of monocyte-derived dendritic cells through an Akt2-dependent pathway and promotes a T-helper type-1 response
Arterioscler. Thromb. Vasc. Biol.
30
582-590
2010
Homo sapiens
Manually annotated by BRENDA team
Doeuvre, L.; Plawinski, L.; Goux, D.; Vivien, D.; Angles-Cano, E.
Plasmin on adherent cells: from microvesiculation to apoptosis
Biochem. J.
432
365-373
2010
Homo sapiens
Manually annotated by BRENDA team
Swedberg, J.E.; Harris, J.M.
Plasmin substrate binding site cooperativity guides the design of potent peptide aldehyde inhibitors
Biochemistry
50
8454-8462
2011
Homo sapiens
Manually annotated by BRENDA team
Teno, N.; Gohda, K.; Wanaka, K.; Sueda, T.; Tsuda, Y.
Identification of novel plasmin inhibitors possessing nitrile moiety as warhead
Bioorg. Med. Chem. Lett.
21
6305-6309
2011
Homo sapiens
Manually annotated by BRENDA team
Venkatraman, L.; Li, H.; Dewey Jr., C.; White, J.; Bhowmick, S.; Yu, H.; Tucker-Kellogg, L.
Steady states and dynamics of urokinase-mediated plasmin activation in silico and in vitro
Biophys. J.
101
1825-1834
2011
Homo sapiens
Manually annotated by BRENDA team
Arkebauer, M.; Kanaparthy, S.; Malayaman, S.; Vosseller, K.; Nielsen, V.
Carbon monoxide and nitric oxide modulate alpha2-antiplasmin and plasmin activity: role of heme
Blood Coagul. Fibrinolysis
22
712-719
2011
Homo sapiens
Manually annotated by BRENDA team
Schaller, J.; Gerber, S.S.
The plasmin-antiplasmin system: structural and functional aspects
Cell. Mol. Life Sci.
68
785-801
2011
Homo sapiens (P00747)
Manually annotated by BRENDA team
Dahiya, M.; Singh, S.; Rajamohan, G.; Sethi, D.; Ashish, D.; Dikshit, K.L.
Intermolecular interactions in staphylokinase-plasmin(ogen) bimolecular complex: function of His43 and Tyr44
FEBS Lett.
585
1814-1820
2011
Homo sapiens
Manually annotated by BRENDA team
Aaltonen, T.; Ollikainen, P.
Effect of microfiltration of milk on plasmin activity
Int. Dairy J.
21
193-197
2011
Bos taurus
Manually annotated by BRENDA team
Okunishi, K.; Sisson, T.H.; Huang, S.K.; Hogaboam, C.M.; Simon, R.H.; Peters-Golden, M.
Plasmin overcomes resistance to prostaglandin E2 in fibrotic lung fibroblasts by reorganizing protein kinase A signaling
J. Biol. Chem.
286
32231-32243
2011
Homo sapiens, Mus musculus, Mus musculus C57BL/6
Manually annotated by BRENDA team
Kanno, Y.; Ishisaki, A.; Kawashita, E.; Chosa, N.; Nakajima, K.; Nishihara, T.; Toyoshima, K.; Okada, K.; Ueshima, S.; Matsushita, K.; Matsuo, O.; Matsuno, H.
Plasminogen/plasmin modulates bone metabolism by regulating the osteoblast and osteoclast function
J. Biol. Chem.
286
8952-8960
2011
Mus musculus
Manually annotated by BRENDA team
Gohda, K.; Teno, N.; Wanaka, K.; Tsuda, Y.
Predicting subsite interactions of plasmin with substrates and inhibitors through computational docking analysis
J. Enzyme Inhib. Med. Chem.
27
:571-577
2011
Homo sapiens
Manually annotated by BRENDA team
Feys, H.B.; Vandeputte, N.; Palla, R.; Peyvandi, F.; Peerlinck, K.; Deckmyn, H.; Lijnen, H.R.; Vanhoorelbeke, K.
Inactivation of ADAMTS13 by plasmin as a potential cause of thrombotic thrombocytopenic purpura
J. Thromb. Haemost.
8
2053-2062
2010
Homo sapiens
Manually annotated by BRENDA team
Martinez-Rizo, A.; Bueno-Topete, M.; Gonzalez-Cuevas, J.; Armendariz-Borunda, J.
Plasmin plays a key role in the regulation of profibrogenic molecules in hepatic stellate cells
Liver Int.
30
298-310
2010
Homo sapiens
Manually annotated by BRENDA team
Li, Q.; Ke, F.; Zhang, W.; Shen, X.; Xu, Q.; Wang, H.; Yu, X.Z.; Leng, Q.; Wang, H.
Plasmin plays an essential role in amplification of psoriasiform skin inflammation in mice
PLoS ONE
6
e16483
2011
Homo sapiens, Mus musculus
Manually annotated by BRENDA team
Chung, M.C.; Tonry, J.H.; Narayanan, A.; Manes, N.P.; Mackie, R.S.; Gutting, B.; Mukherjee, D.V.; Popova, T.G.; Kashanchi, F.; Bailey, C.L.; Popov, S.G.
Bacillus anthracis interacts with plasmin(ogen) to evade C3b-dependent innate immunity
PLoS ONE
6
e18119
2011
Homo sapiens
Manually annotated by BRENDA team
Alves, N.J.; Kline, J.A.
Comparative study on the inhibition of plasmin and delta-plasmin viabenzamidine derivatives
Biochem. Biophys. Res. Commun.
457
358-362
2015
Homo sapiens
Manually annotated by BRENDA team
Varju, I.; Tenekedjiev, K.; Keresztes, Z.; Pap, A.E.; Szabo, L.; Thelwell, C.; Longstaff, C.; Machovich, R.; Kolev, K.
Fractal kinetic behavior of plasmin on the surface of fibrin meshwork
Biochemistry
53
6348-6356
2014
Homo sapiens
Manually annotated by BRENDA team
Swedberg, J.E.; Harris, J.M.
Natural and engineered plasmin inhibitors: applications and design strategies
ChemBioChem
13
336-348
2012
Homo sapiens (P00747), Homo sapiens
Manually annotated by BRENDA team
Buhl, K.; Friis, U.; Svenningsen, P.; Gulaveerasingam, A.; Ovesen, P.; Frederiksen-Moller, B.; Jespersen, B.; Bistrup, C.; Jensen, B.
Urinary plasmin activates collecting duct ENaC current in preeclampsia
Hypertension
60
1346-1351
2012
Homo sapiens
Manually annotated by BRENDA team
Farhat, Y.M.; Al-Maliki, A.A.; Easa, A.; OKeefe, R.J.; Schwarz, E.M.; Awad, H.A.
TGF-beta1 suppresses plasmin and MMP activity in flexor tendon cells via PAI-1: Implications for scarless flexor tendon repair
J. Cell. Physiol.
230
318-326
2015
Mus musculus
Manually annotated by BRENDA team
Gohda, K.; Teno, N.; Wanaka, K.; Tsuda, Y.
Predicting subsite interactions of plasmin with substrates and inhibitors through computational docking analysis
J. Enzyme Inhib. Med. Chem.
27
571-577
2012
Homo sapiens (P00747)
Manually annotated by BRENDA team
Foley, J.H.; Peterson, E.A.; Lei, V.; Wan, L.W.; Krisinger, M.J.; Conway, E.M.
Interplay between fibrinolysis and complement: plasmin cleavage of iC3b modulates immune responses
J. Thromb. Haemost.
13
610-618
2015
Homo sapiens
Manually annotated by BRENDA team
Koch, T.K.; Reuter, M.; Barthel, D.; Boehm, S.; van den Elsen, J.; Kraiczy, P.; Zipfel, P.F.; Skerka, C.
Staphylococcus aureus proteins Sbi and Efb recruit human plasmin to degrade complement C3 and C3b
PLoS ONE
7
e47638
2012
Homo sapiens
Manually annotated by BRENDA team
Briassouli, P.; Halushka, M.K.; Reed, J.H.; Molad, Y.; Fox-Talbot, K.; Buyon, L.; Guzman, E.; Ludomirsky, A.; Clancy, R.M.; Buyon, J.P.
A central role of plasmin in cardiac injury initiated by fetal exposure to maternal anti-Ro autoantibodies
Rheumatology
52
1448-1453
2013
Homo sapiens
Manually annotated by BRENDA team
Brophy, T.M.; Ward, S.E.; McGimsey, T.R.; Schneppenheim, S.; Drakeford, C.; OSullivan, J.M.; Chion, A.; Budde, U.; ODonnell, J.S.
Plasmin cleaves von Willebrand factor at K1491-R1492 in the A1-A2 linker region in a shear- and glycan-dependent manner in vitro
Arterioscler. Thromb. Vasc. Biol.
37
845-855
2017
Homo sapiens
Manually annotated by BRENDA team
Yusova, E.
Plasmin enzymatic activity in the presence of actin
Biopolym. Cell
31
345-350
2015
Homo sapiens
-
Manually annotated by BRENDA team
Law, R.H.P.; Wu, G.; Leung, E.W.W.; Hidaka, K.; Quek, A.J.; Caradoc-Davies, T.T.; Jeevarajah, D.; Conroy, P.J.; Kirby, N.M.; Norton, R.S.; Tsuda, Y.; Whisstock, J.C.
X-ray crystal structure of plasmin with tranexamic acid-derived active site inhibitors
Blood Adv.
1
766-771
2017
Homo sapiens
Manually annotated by BRENDA team
Wise, S.G.; Michael, P.L.; Waterhouse, A.; Santos, M.; Filipe, E.; Hung, J.; Kondyurin, A.; Bilek, M.M.; Ng, M.K.
Immobilization of bioactive plasmin reduces the thrombogenicity of metal surfaces
Colloids Surf. B Biointerfaces
136
944-954
2015
Homo sapiens
Manually annotated by BRENDA team
Castiblanco-Valencia, M.M.; Fraga, T.R.; Pagotto, A.H.; Serrano, S.M.; Abreu, P.A.; Barbosa, A.S.; Isaac, L.
Plasmin cleaves fibrinogen and the human complement proteins C3b and C5 in the presence of Leptospira interrogans proteins A new role of LigA and LigB in invasion and complement immune evasion
Immunobiology
221
679-689
2016
Homo sapiens
Manually annotated by BRENDA team
Stoeckel, M.; Lidolt, M.; Stressler, T.; Fischer, L.; Wenning, M.; Hinrichs, J.
Heat stability of indigenous milk plasmin and proteases from Pseudomonas A challenge in the production of ultra-high temperature milk products
Int. Dairy J.
61
250-261
2016
Bos taurus
-
Manually annotated by BRENDA team
Vijayakumar, S.; Grewell, D.; Annandarajah, C.; Benner, L.; Clark, S.
Quality characteristics and plasmin activity of thermosonicated skim milk and cream
J. Dairy Sci.
98
6678-6691
2015
Bos taurus
Manually annotated by BRENDA team
Al-Horani, R.; Karuturi, R.; White, D.; Desai, U.
Plasmin regulation through allosteric, sulfated, small molecules
Molecules
20
608-624
2015
Homo sapiens
Manually annotated by BRENDA team
Poturnayova, A.; Karpisova, I.; Castillo, G.; Mezo, G.; Kocsis, L.; Csámpai, A.; Keresztes, Z.; Hianik, T.
Detection of plasmin based on specific peptide substrate using acoustic transducer
Sens. Actuators B Chem.
223
591-598
2016
Bos taurus
-
Manually annotated by BRENDA team