Reference on EC 3.4.21.4 - trypsin
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Bode, W.
Aktivierung, Aktivitt und Inhibierung des Rindertrypsins
Naturwissenschaften
66
251-258
1979
Bos taurus
Rick, W.
Trypsin
Methods Enzym. Anal. , 3rd Ed. (Bergmeyer, H. U. , ed. )
1
1052-1063
1974
Bos taurus
-
Walker, J.E.; Keil, B.
Purification and characterisation of different active forms of pork trypsin
Eur. J. Biochem.
32
486-491
1973
Sus scrofa
Johnson, A.; Gautham, N.; Pattabhi, V.
Crystal structure at 1.63 A resolution of the native form of porcine beta-trypsin: revealing an acetate ion binding site and functional water network
Biochim. Biophys. Acta
1435
7-21
1999
Sus scrofa
Steiner, J.M.; Medinger, T.L.; Williams, D.A.
Purification and partial characterization of feline trypsin
Comp. Biochem. Physiol. B
116
87-93
1997
Felis catus
Tanizawa, K.; Kanaoka, Y.; Lawson, W.B.
Inverse substrates trypsin and trypsin-like enzymes
Acc. Chem. Res.
20
337-343
1987
Bos taurus
-
Asgeirsson, B.; Fox, J.W.; Bjarnason, J.B.
Purification and characterization of trypsin from the poikilotherm Gadus morhua
Eur. J. Biochem.
180
85-94
1989
Gadus morhua
Read, R.J.; James, M.N.G.
Refined crystal structure of Streptomyces griseus trypsin at 1.7 A resolution
J. Mol. Biol.
200
523-551
1988
Streptomyces griseus
Kleine, R.; Uhlig, H.; Kretschmer, K.; Marquardt, I.
Reinigung und einige Eigenschaften des Trypsins vom Flusskrebs
Enzymologia
42
155-173
1972
Cambarus affinis, Astacus leptodactylus
Valaitis, A.
Gypsy moth midgut proteinases: purification and characterization of luminal trypsin, elastase and the brush border membrane leucine aminopeptidase
Insect Biochem. Mol. Biol.
25
139-149
1995
Lymantria dispar
Monti, J.C.; Mermoud, A.F.; Jolles, P.
Trypsin in human milk
Experientia
42
39-41
1986
Homo sapiens
Compton, P.D.; Coll, R.J.; Fink, A.L.
Effects of methanol cryosolvents on the structural and catalytic properties of bovine trypsin
J. Biol. Chem.
261
1248-1252
1986
Bos taurus
Guyonnet, V.; Tluscik, F.; Long, P.L.; Polanowski, A.; Travis, J.
Purification and partial characterization of the pancreatic proteolytic enzymes trypsin, chymotrypsin and elastase from the chicken
J. Chromatogr.
852
217-225
1999
Gallus gallus
Yamane, T.; Kobuke, M.; Tsutsui, H.; Toida, T.; Suzuki, A.; Ashida, T.; Kawata, Y.; Skiyama, F.
Crystal structure of Streptomyces erythraeus trypsin at 2.7 resolution
J. Biochem.
110
945-950
1991
Saccharopolyspora erythraea
Johnson, D.A.
Purification and properties of rabbit trypsin
Biochim. Biophys. Acta
452
482-487
1976
Oryctolagus cuniculus
Olafson, R.W.; Smilie, L.B.
Enzymic and physicochemical properties of Streptomyces griseus trypsin
Biochemistry
14
1161-1167
1975
Streptomyces griseus
Ohlsson, K.; Tegner, H.
Anionic and cationic dog trypsin. Isolation and partial characterization
Biochim. Biophys. Acta
317
328-337
1973
Canis lupus familiaris
Male, R.; Lorens, J.B.; Smalas, A.O.; Torrissen, K.R.
Molecular cloning and characterization of anionic and cationic variants of trypsin from Atlantic salmon
Eur. J. Biochem.
232
677-685
1995
Salmo salar
Jeohn, G.H.; Serizawa, S.; Iwamatsu, A.; Takahashi, K.
Isolation and characterization of gastric trypsin from the microsomal fraction of porcine gastric antral mucosa
J. Biol. Chem.
270
14748-14755
1995
Sus scrofa
Wang, E.C.W.; Hung, S.H.; Cahoon, M.; Hedstrom, L.
The role of the Cys191-Cys220 disulfide bond in trypsin: new targets for engineering substrate specificity
Protein Eng.
10
405-411
1997
Rattus norvegicus
Venkatesh, R.; Sundaram, P.V.
Modulation of stability properties of bovine trypsin after in vitro structural changes with a variety of chemical modifiers
Protein Eng.
11
691-698
1998
Bos taurus
Osir, E.O.; Abubakar, L.; Imbuga, M.O.
Purification and characterization of a midgut lectin-trypsin complex from the tsetse fly Glossina longipennis
Parasitol. Res.
81
276-281
1995
Glossina longipennis
Huang, Q.; Wang, Z.; Li, Y.; Liu, S.; Tang, Y.
Refined 1.8 A resolution crystal structure of the porcine epsilon-trypsin
Biochim. Biophys. Acta
1209
77-82
1994
Sus scrofa
Prestrelski, S.J.; Byler, D.M.; Liebman, M.N.
Comparison of various molecular forms of bovine trypsin: correlation of infrared spectra with X-ray crystal structures
Biochemistry
30
133-143
1991
Bos taurus
McGrath, M.E.; Haymore, B.L.; Summers, N.L.; Craik, C.S.; Fletterick, R.J.
Structure of an engineered, metal-actuated switch in trypsin
Biochemistry
32
1914-1919
1993
Rattus norvegicus
Willett, W.S.; Gillmor, S.A.; Perona, J.J.; Flettrick, R.J.; Craik, C.S.
Engineered metal regulation of trypsin specificity
Biochemistry
34
2172-2180
1995
Rattus norvegicus
Hernandez-Cortes, P.; Cerenius, L.; Garcia-Carreno, F.; Sderhll, K.
Trypsin from Pacifastacus leniusculus hepatopancreas: purification and cDNA cloning of the synthesized zymogen
Biol. Chem.
380
499-501
1999
Pacifastacus leniusculus
Gaboriaud, C.; Guy-Crotte, O.; Forest, E.; Fontecilla-Camps, J.C.
Crystal structure of human trypsin 1: unexpected phosphorylation of Tyr151
J. Mol. Biol.
259
995-1010
1996
Homo sapiens
Ogden, J.M.; O'Keefe, S.J.D.; Marks, I.N.
Development of a method for the purification of human trypsin by a single step affinity chromatography suitable for human isotope incorporation studies
Clin. Chim. Acta
212
141-147
1992
Homo sapiens
Shtelzer, S.; Rappoport, S.; Avnir, D.; Ottolenghi, M.; Braun, S.
Properties of trypsin and of acid phosphatase immobilized in sol-gel glass matrices
Biotechnol. Appl. Biochem.
15
227-235
1992
Bos taurus
Rodgers, K.J.; Melrose, J.; Ghosh, P.
Biotinylated trypsin and its application as a sensitive, versatile probe for the detection and characterisation of an ovine chondrocyte serine proteinase inhibitor using Western blotting
Electrophoresis
17
213-218
1996
Bos taurus
Chobert, J.M.; Briant, L.; Leonil, J.; Molle, D.; Haertle, T.
Engineering of trypsin and its impact on beta-casein processing
Nahrung
42
135-138
1998
Rattus norvegicus
Blanco, R.M.; Alvaron, G.; Guisan, J.M.
Enzyme reaction engineering: design of peptide synthesis by stabilized trypsin
Enzyme Microb. Technol.
13
573-583
1991
Bos taurus
Lee, K.; Ozanne, S.E.; Rowe, I.C.M.; Hales, C.N.; Ashford, M.L.J.
The effects of trypsin on ATP-sensitive potassium channel properties and sulfonylurea receptors in the CRI-G1 insulin-secreting cell line
Mol. Pharmacol.
46
176-185
1994
Rattus norvegicus
Foucault, G.; Seydoux, F.; Yon, J.
Comparative kinetic properties of alpha, beta and psi form of trypsin
Eur. J. Biochem.
47
295-302
1974
Bos taurus
Zhu, G.; Huang, Q.; Qian, M.; Jia, Y.; Tang, Y.
X-ray studies on two forms of bovine beta-trypsin crystals in neat cyclohexane
Biochim. Biophys. Acta
1429
142-150
1998
Bos taurus (P00760), Bos taurus
Stevenson, K.J.; Voordouw, J.K.
Characterization of trypsin and elastase from the moose (Alces alces) I. Amino acid composition and specificity towards polypeptides
Biochim. Biophys. Acta
386
324-331
1975
Alces alces
Kleine, R.; Spangenberg, P.; Flemming, C.
Herstellung and einige Eigenschaften von immobilisiertem Trypsin des Flusskrebses Cambarus affinis say
Hoppe-Seyler's Z. Physiol. Chem.
357
629-639
1976
Cambarus affinis
Wu, H.L.; Kundrot, C.; Bender, M.L.
The denaturation of trypsin
Biochem. Biophys. Res. Commun.
107
742-745
1982
Bos taurus
Rester, U.; Moser, M.; Huber, R.; Bode, W.
L-Isoaspartate 115 of porcine beta-trypsin promotes crystallization of its complex with bdellastasin
Acta Crystallogr. Sect. D
56
581-588
2000
Sus scrofa
-
Deepthi, S.; Johnson, A.; Pattabhi, V.
Structures of porcine beta-trypsin-detergent complexes: the stabilization of proteins through hydrophilic binding of polydocanol
Acta Crystallogr. Sect. D
57
1506-1512
2001
Sus scrofa
Leiros, H.K.; McSweeney, S.M.; Smalas, A.O.
Atomic resolution structures of trypsin provide insight into structural radiation damage
Acta Crystallogr. Sect. D
57
488-497
2001
salmon, Bos taurus (P00760)
Rypniewski, W.R.; Ostergaard, P.R.; Norregaard-Madsen, M.; Dauter, M.; Wilson, K.S.
Fusarium oxysporum trypsin at atomic resolution at 100 and 283 K: a study of ligand binding
Acta Crystallogr. Sect. D
57
8-19
2001
Fusarium oxysporum (P35049), Fusarium oxysporum
Pal, G.; Patthy, A.; Antal, J.; Graf, L.
Mutant rat trypsin selectively cleaves tyrosyl peptide bonds
Anal. Biochem.
326
190-199
2004
Rattus norvegicus
Schimoler-O'Rourke, R.; Richardson, M.; Selitrennikoff, C.P.
Zeamatin inhibits trypsin and alpha-amylase activities
Appl. Environ. Microbiol.
67
2365-2366
2001
Sus scrofa
Lesner, A.; Kupryszewski, G.; Rolka, K.
Chromogenic substrates of bovine beta-trypsin: the influence of an amino acid residue in P1 position on their interaction with the enzyme
Biochem. Biophys. Res. Commun.
285
1350-1353
2001
Bos taurus
Marana, S.R.; Lopes, A.R.; Juliano, L.; Juliano, M.A.; Ferreira, C.; Terra, W.R.
Subsites of trypsin active site favor catalysis or substrate binding
Biochem. Biophys. Res. Commun.
290
494-497
2002
Periplaneta americana
Zablotna, E.; Kazmierczak, K.; Jaskiewicz, A.; Stawikowski, M.; Kupryszewski, G.; Rolka, K.
Chemical synthesis and kinetic study of the smallest naturally occurring trypsin inhibitor SFTI-1 isolated from sunflower seeds and its analogues
Biochem. Biophys. Res. Commun.
292
855-859
2002
Bos taurus
Mitsudo, K.; Jayakumar, A.; Henderson, Y.; Frederick, M.J.; Kang, Y.; Wang, M.; El-Naggar, A.K.; Clayman, G.L.
Inhibition of serine proteinases plasmin, trypsin, subtilisin A, cathepsin G, and elastase by LEKTI: a kinetic analysis
Biochemistry
42
3874-3881
2003
Homo sapiens
Page, M.J.; Wong, S.L.; Hewitt, J.; Strynadka, N.C.; MacGillivray, R.T.
Engineering the primary substrate specificity of Streptomyces griseus trypsin
Biochemistry
42
9060-9066
2003
Streptomyces griseus (P00775), Streptomyces griseus
Transue, T.R.; Krahn, J.M.; Gabel, S.A.; DeRose, E.F.; London, R.E.
X-ray and NMR characterization of covalent complexes of trypsin, borate, and alcohols
Biochemistry
43
2829-2839
2004
Sus scrofa (P00761), Sus scrofa
Park, H.; Chi, Y.M.
The enhancement of electrostriction caused by lowering the solvent dielectric constant leads to the decrease of activation energy in trypsin catalysis
Biochim. Biophys. Acta
1568
53-59
2001
Bos taurus
Erba, F.; Fiorucci, L.; Sommerhoff, C.P.; Coletta, M.; Ascoli, F.
Kinetic and thermodynamic analysis of leech-derived tryptase inhibitor interaction with bovine tryptase and bovine trypsin
Biol. Chem.
381
1117-1122
2000
Bos taurus
Rauh, D.; Reyda, S.; Klebe, G.; Stubbs, M.T.
Trypsin mutants for structure-based drug design: expression, refolding and crystallisation
Biol. Chem.
383
1309-1314
2002
Bos taurus
Woodard, S.L.; Mayor, J.M.; Bailey, M.R.; Barker, D.K.; Love, R.T.; Lane, J.R.; Delaney, D.E.; McComas-Wagner, J.M.; Mallubhotla, H.D.; Hood, E.E.; Dangott, L.J.; Tichy, S.E.; Howard, J.A.
Maize (Zea mays)-derived bovine trypsin: characterization of the first large-scale, commercial protein product from transgenic plants
Biotechnol. Appl. Biochem.
38
123-130
2003
Bos taurus
Kishimura, H.; Hayashi, K.
Isolation and characteristics of trypsin from pyloric ceca of the starfish Asterina pectinifera
Comp. Biochem. Physiol. B
132
485-490
2002
Patiria pectinifera
Ruoppolo, M.; Amoresano, A.; Pucci, P.; Pascarella, S.; Polticelli, F.; Trovato, M.; Menegatti, E.; Ascenzi, P.
Characterization of five new low-molecular-mass trypsin inhibitors from white mustard (Sinapis alba L.) seed
Eur. J. Biochem.
267
6486-6492
2000
Bos taurus
Volpicella, M.; Ceci, L.R.; Cordewener, J.; America, T.; Gallerani, R.; Bode, W.; Jongsma, M.A.; Beekwilder, J.
Properties of purified gut trypsin from Helicoverpa zea, adapted to proteinase inhibitors
Eur. J. Biochem.
270
10-19
2003
Helicoverpa zea (Q9NB82), Helicoverpa zea
Hijikata-Okunomiya, A.; Tamao, Y.; Kikumoto, R.; Okamoto, S.
Selective inhibition of trypsin by (2R,4R)-4-phenyl-1-[Nalpha-(7-methoxy-2-naphthalenesulfonyl)-L-arginyl]-2-piperidinecarboxylic acid
J. Biol. Chem.
275
18995-18999
2000
Bos taurus (P00760)
Schmidt, A.; Jelsch, C.; Ostergaard, P.; Rypniewski, W.; Lamzin, V.S.
Trypsin revisited: crystallography AT (SUB) atomic resolution and quantum chemistry revealing details of catalysis
J. Biol. Chem.
278
43357-43362
2003
Fusarium oxysporum (P35049)
Koepke, J.; Ermler, U.; Warkentin, E.; Wenzl, G.; Flecker, P.
Crystal structure of cancer chemopreventive Bowman-Birk inhibitor in ternary complex with bovine trypsin at 2.3.ANG. resolution. Structural basis of Janus-faced serine protease inhibitor specificity
J. Mol. Biol.
298
477-491
2000
Bos taurus
Toyota, E.; Ng, K.K.; Sekizaki, H.; Itoh, K.; Tanizawa, K.; James, M.N.
X-ray crystallographic analyses of complexes between bovine beta-trypsin and Schiff base copper(II) or iron(III) chelates
J. Mol. Biol.
305
471-479
2001
Bos taurus
Dullweber, F.; Stubbs, M.T.; Musil, D.; Sturzebecher, J.; Klebe, G.
Factorising ligand affinity: a combined thermodynamic and crystallographic study of trypsin and thrombin inhibition
J. Mol. Biol.
313
593-614
2001
Fusarium oxysporum
Toyota, E.; Ng, K.K.; Kuninaga, S.; Sekizaki, H.; Itoh, K.; Tanizawa, K.; James, M.N.
Crystal structure and nucleotide sequence of an anionic trypsin from chum salmon (Oncorhynchus keta) in comparison with Atlantic salmon (Salmo salar) and bovine trypsin
J. Mol. Biol.
324
391-397
2002
Oncorhynchus keta (Q8AV11), Oncorhynchus keta
Reyda, S.; Sohn, C.; Klebe, G.; Rall, K.; Ullmann, D.; Jakubke, H.D.; Stubbs, M.T.
Reconstructing the binding site of factor Xa in trypsin reveals ligand-induced structural plasticity
J. Mol. Biol.
325
963-977
2003
Rattus norvegicus
Ahsan, M.N.; Watabe, S.
Kinetic and structural properties of two isoforms of trypsin isolated from the viscera of Japanese anchovy, Engraulis japonicus
J. Protein Chem.
20
49-58
2001
Engraulis japonicus
Mello, G.C.; Oliva, M.L.V.; Sumikawa, J.T.; Machado, O.L.T.; Marangoni, S.; Novello, J.C.; Macedo, M.L.R.
Purification and characterization of a new trypsin inhibitor from Dimorphandra mollis seeds
J. Protein Chem.
20
625-632
2002
Bos taurus
Leiros, H.K.S.; Brandsdal, B.O.; Andersen, O.A.; Os, V.; Leiros, I.; Helland, R.; Otlewski, J.; Willassen, N.P.; Smalas, A.O.
Trypsin specificity as elucidated by LIE calculations, X-ray structures, and association constant measurements
Protein Sci.
13
1056-1070
2004
Bos taurus, salmon
Melo, F.R.; Rigden, D.J.; Franco, O.L.; Mello, L.V.; Ary, M.B.; Grossi de Sa, M.F.; Bloch, C.Jr.
Inhibition of trypsin by cowpea thionin: characterization, molecular modeling, and docking
Proteins Struct. Funct. Genet.
48
311-319
2002
Bos taurus
Ramjee, M.K.; Henderson, I.M.; McLoughlin, S.B.; Padova, A.
The kinetic and structural characterization of the reaction of nafamostat with bovine pancreatic trypsin
Thromb. Res.
98
559-569
2000
Bos taurus
Ladisch, M.R.; Kohlmann, K.L.
Recombinant human insulin
Biotechnol. Prog.
8
469-478
1992
Sus scrofa
Schmidt, A.; Lamzin, V.S.
Extraction of functional motion in trypsin crystal structures
Acta crystallogr. Sect. D
61
1132-1139
2005
Fusarium oxysporum
Stenman, M.; Ainola, M.; Valmu, L.; Bjartell, A.; Ma, G.; Stenman, U.H.; Sorsa, T.; Luukkainen, R.; Konttinen, Y.T.
Trypsin-2 degrades human type II collagen and is expressed and activated in mesenchymally transformed rheumatoid arthritis synovitis tissue
Am. J. Pathol.
167
1119-1124
2005
Bos taurus, Homo sapiens
Wu, J.; Liu, F.; Nilsson, A.; Duan, R.D.
Pancreatic trypsin cleaves intestinal alkaline sphingomyelinase from mucosa and enhances the sphingomyelinase activity
Am. J. Physiol. Gastrointest. Liver Physiol.
287
G967-G973
2004
Sus scrofa
Ulitina, N.N.; Khablyuk, V.V.; Proskuryakov, M.T.
Purification and properties of serine proteinases from European catfish Silurus glanis L. pancreas
Appl. Biochem. Microbiol.
41
139-144
2005
Silurus glanis
-
Zablotna, E.; Dysasz, H.; Lesner, A.; Jaskiewicz, A.; Kazmierczak, K.; Miecznikowska, H.; Rolka, K.
A simple method for selection of trypsin chromogenic substrates using combinatorial chemistry approach
Biochem. Biophys. Res. Commun.
319
185-188
2004
Bos taurus
Page, M.J.; Bleackley, M.R.; Wong, S.; MacGillivray, R.T.; Di Cera, E.
Conversion of trypsin into a Na(+)-activated enzyme
Biochemistry
45
2987-2993
2006
Streptomyces griseus (P00775), Streptomyces griseus
Cuccioloni, M.; Sparapani, L.; Amici, M.; Lupidi, G.; Eleuteri, A.M.; Angeletti, M.
Kinetic and equilibrium characterization of the interaction between bovine trypsin and I-ovalbumin
Biochim. Biophys. Acta
1702
199-207
2004
Bos taurus
Sienczyk, M.; Oleksyszyn, J.
Inhibition of trypsin and urokinase by Cbz-amino(4-guanidinophenyl)methanephosphonate aromatic ester derivatives: the influence of the ester group on their biological activity
Bioorg. Med. Chem. Lett.
16
2886-2890
2006
Bos taurus
Ma, W.; Tang, C.; Lai, L.
Specificity of trypsin and chymotrypsin: loop-motion-controlled dynamic correlation as a determinant
Biophys. J.
89
1183-1193
2005
Bos taurus (P00760)
Uchikoba, T.; Fukumoto, S.; Itakura, T.; Okubo, M.; Tomokiyo, K.; Arima, K.; Yonezawa, H.
Detection of hydrolytic activity of trypsin with a fluorescence-chymotryptic peptide on a TLC plate
Biosci. Biotechnol. Biochem.
68
222-225
2004
Lycoris radiata
Villalonga, M.L.; Reyes, G.; Fragoso, A.; Cao, R.; Fernandez, L.; Villalonga, R.
Chemical glycosidation of trypsin with O-carboxymethyl-poly-beta-cyclodextrin: catalytic and stability properties
Biotechnol. Appl. Biochem.
41
217-223
2005
Bos taurus
Grishina, Z.; Ostrowska, E.; Halangk, W.; Sahin-Toth, M.; Reiser, G.
Activity of recombinant trypsin isoforms on human proteinase-activated receptors (PAR): mesotrypsin cannot activate epithelial PAR-1, -2, but weakly activates brain PAR-1
Br. J. Pharmacol.
146
990-999
2005
Homo sapiens
Sainz, J.C.; Garcia-Carreno, F.L.; Hernandez-Cortes, P.
Penaeus vannamei isotrypsins: purification and characterization
Comp. Biochem. Physiol. B
138B
155-162
2004
Penaeus vannamei
-
Castillo-Yanez, F.J.; Pacheco-Aguilar, R.; Garcia-Carreno, F.L.; Navarrete-Del Toro, M.d.
Isolation and characterization of trypsin from pyloric caeca of Monterey sardine Sardinops sagax caerulea
Comp. Biochem. Physiol. B
140B
91-98
2005
Sardinops caeruleus
-
Kurtovic, I.; Marshall, S.N.; Simpson, B.K.
Isolation and characterization of a trypsin fraction from the pyloric ceca of chinook salmon (Oncorhynchus tshawytscha)
Comp. Biochem. Physiol. B
143
432-440
2006
Oncorhynchus tshawytscha
von Elert, E.; Agrawal, M.K.; Gebauer, C.; Jaensch, H.; Bauer, U.; Zitt, A.
Protease activity in gut of Daphnia magna: evidence for trypsin and chymotrypsin enzymes
Comp. Biochem. Physiol. B Biochem. Mol. Biol.
137
287-296
2004
Daphnia magna
Kishimura, H.; Hayashi, K.; Miyashita, Y.; Nonami, Y.
Characteristics of trypsins from the viscera of true sardine (Sardinops melanostictus) and the pyloric ceca of arabesque greenling (Pleuroprammus azonus)
Food Chem.
97
65-70
2006
Sardinops melanostictus, Pleurogrammus azonus
Klomklao, S.; Benjakul, S.; Visessanguan, W.; Kishimura, H.; Simpson, B.K.
Purification and characterization of trypsin from the spleen of Tongol tuna (Thunnus tonggol)
J. Agric. Food Chem.
54
5617-5622
2006
Thunnus tonggol
Schmidt, A.E.; Chand, H.S.; Cascio, D.; Kisiel, W.; Bajaj, S.P.
Crystal structure of Kunitz domain 1 (KD1) of tissue factor pathway inhibitor-2 in complex with trypsin. Implications for KD1 specificity of inhibition
J. Biol. Chem.
280
27832-27838
2005
Bos taurus
Shamaladevi, N.; Pattabhi, V.
Secondary binding site of trypsin: revealed by crystal structure of trypsin-peptide complex
J. Biomol. Struct. Dyn.
22
635-642
2005
Sus scrofa
Benureau, Y.; Huet, J.C.; Charpilienne, A.; Poncet, D.; Cohen, J.
Trypsin is associated with the rotavirus capsid and is activated by solubilization of outer capsid proteins
J. Gen. Virol.
86
3143-3151
2005
Sus scrofa
Wang, F.; Wang, C.; Li, M.; Zhang, J.P.; Gui, L.L.; An, X.M.; Chang, W.R.
Crystal structure of earthworm fibrinolytic enzyme component B: a novel, glycosylated two-chained trypsin
J. Mol. Biol.
348
671-685
2005
Eisenia fetida
Lindstad, R.I.; Sylte, I.; Mikalsen, S.O.; Seglen, P.O.; Berg, E.; Winberg, J.O.
Pancreatic trypsin activates human promatrix metalloproteinase-2
J. Mol. Biol.
350
682-698
2005
Sus scrofa
Di Profio, G.; Curcio, E.; Drioli, E.
Trypsin crystallization by membrane-based techniques
J. Struct. Biol.
150
41-49
2005
Bos taurus
Kang, K.; Kan, C.; Yeung, A.; Liu, D.
The properties of covalently immobilized trypsin on soap-free P(MMA-EA-AA) latex particles
Macromol. Biosci.
5
344-351
2005
Sus scrofa
Jonsdottir, G.; Bjarnason, J.B.; Gudmundsdottir, A.
Recombinant cold-adapted trypsin I from Atlantic cod - expression, purification, and identification
Protein Expr. Purif.
33
110-122
2004
Gadus morhua
Finehout, E.J.; Cantor, J.R.; Lee, K.H.
Kinetic characterization of sequencing grade modified trypsin
Proteomics
5
2319-2321
2005
Sus scrofa
Liu, X.; Broshears, W.C.; Reilly, J.P.
Probing the structure and activity of trypsin with amidination
Anal. Biochem.
367
13-19
2007
Bos taurus
Stosova, T.; Sebela, M.; Rehulka, P.; Sedo, O.; Havlis, J.; Zdrahal, Z.
Evaluation of the possible proteomic application of trypsin from Streptomyces griseus
Anal. Biochem.
376
94-102
2008
Streptomyces griseus (P00775), Streptomyces griseus
Magalhaes, C.P.; Fragoso, R.R.; Souza, D.S.; Barbosa, A.E.; Silva, C.P.; Finardi-Filho, F.; da Silva, M.C.; Rocha, T.L.; Franco, O.L.; Grossi-de-Sa, M.F.
Molecular and structural characterization of a trypsin highly expressed in larval stage of Zabrotes subfasciatus
Arch. Insect Biochem. Physiol.
66
169-182
2007
Zabrotes subfasciatus
Gombos, L.; Kardos, J.; Patthy, A.; Medveczky, P.; Szilagyi, L.; Malnasi-Csizmadia, A.; Graf, L.
Probing conformational plasticity of the activation domain of trypsin: the role of glycine hinges
Biochemistry
47
1675-1684
2008
Homo sapiens
Toyota, E.; Iyaguchi, D.; Sekizaki, H.; Itoh, K.; Tanizawa, K.
Kinetic properties of three isoforms of trypsin isolated from the pyloric caeca of chum salmon (Oncorhynchus keta)
Biol. Pharm. Bull.
30
1648-1652
2007
Bos taurus, Oncorhynchus keta
Wu, Z.; Jiang, G.; Xiang, P.; Yang, D.; Wang, N.
Purification and characterization of trypsin-like enzymes from North Pacific krill (Euphausia pacifica)
Biotechnol. Lett.
30
67-72
2008
Euphausia pacifica
Klomklao, S.; Benjakul, S.; Visessanguan, W.; Kishimura, H.; Simpson, B.K.; Saeki, H.
Trypsins from yellowfin tuna (Thunnus albacores) spleen: purification and characterization
Comp. Biochem. Physiol. B Biochem. Mol. Biol.
144
47-56
2006
Thunnus albacares
Forbes, R.T.; Barry, B.W.; Elkordy, A.A.
Preparation and characterisation of spray-dried and crystallised trypsin: FT-Raman study to detect protein denaturation after thermal stress
Eur. J. Pharm. Sci.
30
315-323
2007
Bos taurus
Szepessy, E.; Sahin-Toth, M.
Human mesotrypsin exhibits restricted S1 subsite specificity with a strong preference for small polar side chains
FEBS J.
273
2942-2954
2006
Homo sapiens
Asgeirsson, B.; Cekan, P.
Microscopic rate-constants for substrate binding and acylation in cold-adaptation of trypsin I from Atlantic cod
FEBS Lett.
580
4639-4644
2006
Bos taurus, Gadus morhua
Kishimura, H.; Klomklao, S.; Benjakul, S.; Chun, B.
Characteristics of trypsin from the pyloric ceca of walleye pollock (Theragra chalcogramma)
Food Chem.
106
194-199
2007
Gadus chalcogrammus
-
Lopes, A.R.; Juliano, M.A.; Marana, S.R.; Juliano, L.; Terra, W.R.
Substrate specificity of insect trypsins and the role of their subsites in catalysis
Insect Biochem. Mol. Biol.
36
130-140
2006
Musca domestica, Periplaneta americana, Tenebrio molitor, Diatraea saccharalis
Santos, A.M.; Santana, M.A.; Gomide, F.T.; Miranda, A.A.; Oliveira, J.S.; Boas, F.A.; Vasconcelos, A.B.; Bemquerer, M.P.; Santoro, M.M.
Physical-chemical characterization and stability study of alpha-trypsin at pH 3.0 by differential scanning calorimetry
Int. J. Biol. Macromol.
42
278-284
2008
Bos taurus
Treetharnmathurot, B.; Ovartlarnporn, C.; Wungsintaweekul, J.; Duncan, R.; Wiwattanapatapee, R.
Effect of PEG molecular weight and linking chemistry on the biological activity and thermal stability of PEGylated trypsin
Int. J. Pharm.
357
252-259
2008
Bos taurus
Klomklao, S.; Benjakul, S.; Visessanguan, W.; Kishimura, H.; Simpson, B.K.
29 kDa trypsin from the pyloric ceca of Atlantic bonito (Sarda sarda): recovery and characterization
J. Agric. Food Chem.
55
4548-4553
2007
Sarda sarda
Takekawa, H.; Ina, C.; Sato, R.; Toma, K.; Ogawa, H.
Novel carbohydrate-binding activity of pancreatic trypsins to N-linked glycans of glycoproteins
J. Biol. Chem.
281
8528-8538
2006
Bos taurus, Sus scrofa
Knecht, W.; Cottrell, G.S.; Amadesi, S.; Mohlin, J.; Skaregaerde, A.; Gedda, K.; Peterson, A.; Chapman, K.; Hollenberg, M.D.; Vergnolle, N.; Bunnett, N.W.
Trypsin IV or mesotrypsin and p23 cleave protease-activated receptors 1 and 2 to induce inflammation and hyperalgesia
J. Biol. Chem.
282
26089-26100
2007
Homo sapiens, Rattus norvegicus
Bengrine, A.; Li, J.; Hamm, L.L.; Awayda, M.S.
Indirect activation of the epithelial Na+ channel by trypsin
J. Biol. Chem.
282
26884-26896
2007
Bos taurus
Diaz-Mendoza, M.; Farinos, G.P.; Castanera, P.; Hernandez-Crespo, P.; Ortego, F.
Proteolytic processing of native Cry1Ab toxin by midgut extracts and purified trypsins from the Mediterranean corn borer Sesamia nonagrioides
J. Insect Physiol.
53
428-435
2007
Sesamia nonagrioides
Wang, Y.; Luo, W.; Wartmann, T.; Halangk, W.; Sahin-Toth, M.; Reiser, G.
Mesotrypsin, a brain trypsin, activates selectively proteinase-activated receptor-1, but not proteinase-activated receptor-2, in rat astrocytes
J. Neurochem.
99
759-769
2006
Homo sapiens
Garbers, E.; Mitloehner, R.; Georgieva, R.; Baeumler, H.
Activity of immobilized trypsin in the layer structure of polyelectrolyte microcapsules (PEMC)
Macromol. Biosci.
7
1243-1249
2007
Homo sapiens
Palsdottir, H.M.; Gudmundsdottir, A.
Expression and purification of a cold-adapted group III trypsin in Escherichia coli
Protein Expr. Purif.
51
243-252
2007
Gadus morhua
Toth, J.; Simon, Z.; Medveczky, P.; Gombos, L.; Jelinek, B.; Szilagyi, L.; Graf, L.; Malnasi-Csizmadia, A.
Site directed mutagenesis at position 193 of human trypsin 4 alters the rate of conformational change during activation: role of local internal viscosity in protein dynamics
Proteins
67
1119-1127
2007
Homo sapiens
Legowska, A.; Debowski, D.; Lesner, A.; Wysocka, M.; Rolka, K.
Introduction of non-natural amino acid residues into the substrate-specific P(1) position of trypsin inhibitor SFTI-1 yields potent chymotrypsin and cathepsin G inhibitors
Bioorg. Med. Chem.
17
3302-3307
2009
Bos taurus
Ye, X.; Bun Ng, T.
A trypsin-chymotrypsin inhibitor with antiproliferative activity from small glossy black soybeans
Planta Med.
75
550-556
2009
Bos taurus
Cheung, A.H.; Wong, J.H.; Ng, T.B.
Trypsin-chymotrypsin inhibitors from Vigna mungo seeds
Protein Pept. Lett.
16
277-284
2009
Bos taurus
Deppe, M.; Risopatron, J.; Sanchez, R.
Trypsin and chymotrypsin are involved in the progesterone-induced acrosome reaction in canine spermatozoa
Reprod. Domest. Anim.
45
453-457
2010
Canis lupus familiaris
Leone, P.; Roussel, A.; Kellenberger, C.
Structure of Locusta migratoria protease inhibitor 3 (LMPI-3) in complex with Fusarium oxysporum trypsin
Acta Crystallogr. Sect. D
64
1165-1171
2008
Fusarium oxysporum
Jiang, C.; Bao, R.; Chen, Y.
Expression, purification, crystallization and preliminary X-ray diffraction analysis of Sagittaria sagittifolia arrowhead protease inhibitor API-A in complex with bovine trypsin
Acta Crystallogr. Sect. F
64
1060-1062
2008
Bos taurus
Paczek, L.; Michalska, W.; Bartlomiejczyk, I.
Trypsin, elastase, plasmin and MMP-9 activity in the serum during the human ageing process
Age Ageing
37
318-323
2008
Homo sapiens
Elphick, D.; Liddell, S.; Mahida, Y.R.
Impaired luminal processing of human defensin-5 in Crohns disease: persistence in a complex with chymotrypsinogen and trypsin
Am. J. Pathol.
172
702-713
2008
Homo sapiens
Marchbank, T.; Weaver, G.; Nilsen-Hamilton, M.; Playford, R.J.
Pancreatic secretory trypsin inhibitor is a major motogenic and protective factor in human breast milk
Am. J. Physiol. Gastrointest. Liver Physiol.
296
G697-G703
2009
Rattus norvegicus
Nesterov, V.; Dahlmann, A.; Bertog, M.; Korbmacher, C.
Trypsin can activate the epithelial sodium channel (ENaC) in microdissected mouse distal nephron
Am. J. Physiol. Renal Physiol.
295
F1052-F1062
2008
Mus musculus
Rungrotmongkol, T.; Decha, P.; Malaisree, M.; Sompornpisut, P.; Hannongbua, S.
Comment on "Cleavage mechanism of the H5N1 hemagglutinin by trypsin and furin" [Amino Acids 2008, January 31, Doi: 10.1007/s00726-007-0611-3]
Amino Acids
35
511-512
2008
Homo sapiens
Krenkova, J.; Lacher, N.A.; Svec, F.
Highly efficient enzyme reactors containing trypsin and endoproteinase LysC immobilized on porous polymer monolith coupled to MS suitable for analysis of antibodies
Anal. Chem.
81
2004-2012
2009
Bos taurus
Mayoral, J.G.; Alarcon, F.J.; Martinez, T.F.; Barranco, P.; Noriega, F.
An improved end-point fluorimetric procedure for the determination of low amounts of trypsin activity in biological samples using rhodamine-110-based substrates
Appl. Biochem. Biotechnol.
160
1-8
2009
Sus scrofa
Lemeire, E.; Borovsky, D.; Van Camp, J.; Smagghe, G.
Effect of Ace inhibitors and TMOF on growth, development, and trypsin activity of larval Spodoptera littoralis
Arch. Insect Biochem. Physiol.
69
199-208
2008
Spodoptera littoralis
Hehemann, J.H.; Redecke, L.; Murugaiyan, J.; von Bergen, M.; Betzel, C.; Saborowski, R.
Autoproteolytic stability of a trypsin from the marine crab Cancer pagurus
Biochem. Biophys. Res. Commun.
370
566-571
2008
Cancer pagurus
Song, G.; Zhou, M.; Chen, W.; Chen, T.; Walker, B.; Shaw, C.
HV-BBI--a novel amphibian skin Bowman-Birk-like trypsin inhibitor
Biochem. Biophys. Res. Commun.
372
191-196
2008
Homo sapiens
Wu, Z.L.; Ethen, C.; Hickey, G.E.; Jiang, W.
Active 1918 pandemic flu viral neuraminidase has distinct N-glycan profile and is resistant to trypsin digestion
Biochem. Biophys. Res. Commun.
379
749-753
2009
Homo sapiens
Miao, A.; Dai, Y.; Ji, Y.; Jiang, Y.; Lu, Y.
Liquid-chromatographic and mass-spectrometric identification of lens proteins using microwave-assisted digestion with trypsin-immobilized magnetic nanoparticles
Biochem. Biophys. Res. Commun.
380
603-608
2009
Bos taurus
Chen, N.; Zou, J.; Wang, S.; Ye, Y.; Huang, Y.; Gadda, G.; Yang, J.J.
Designing protease sensors for real-time imaging of trypsin activation in pancreatic cancer cells
Biochemistry
48
3519-3526
2009
Homo sapiens
Kang, Z.; Jiang, J.H.; Wang, D.; Liu, K.; Du, L.F.
Kunitz-type trypsin inhibitor with high stability from Spinacia oleracea L. seeds
Biochemistry
74
102-109
2009
Bos taurus
Li, J.; Wu, J.; Wang, Y.; Xu, X.; Liu, T.; Lai, R.; Zhu, H.
A small trypsin inhibitor from the frog of Odorrana grahami
Biochimie
90
1356-1361
2008
Bos taurus
Yang, L.; Dong, W.; He, J.; Ren, X.; Yan, W.
Expression and purification of natural N-terminal recombinant bovine pancreatic trypsin inhibitor from Pichia pastoris
Biol. Pharm. Bull.
31
1680-1685
2008
Rattus norvegicus
Oda, A.; Yamaotsu, N.; Hirono, S.; Takahashi, O.
Brownian dynamics simulations of a wild type and mutants of bovine pancreatic trypsin inhibitors
Biol. Pharm. Bull.
31
2182-2186
2008
Bos taurus
Kluchova, K.; Zboril, R.; Tucek, J.; Pecova, M.; Zajoncova, L.; Safarik, I.; Mashlan, M.; Markova, I.; Jancik, D.; Sebela, M.; Bartonkova, H.; Bellesi, V.; Novak, P.; Petridis, D.
Superparamagnetic maghemite nanoparticles from solid-state synthesis - Their functionalization towards peroral MRI contrast agent and magnetic carrier for trypsin immobilization
Biomaterials
30
2855-2863
2009
Bos taurus
Legowska, A.; Bulak, E.; Wysocka, M.; Jaskiewicz, A.; Lesner, A.; Debowski, D.; Rolka, K.
Peptomeric analogues of trypsin inhibitor SFTI-1 isolated from sunflower seeds
Bioorg. Med. Chem.
16
5644-5652
2008
Bos taurus
Izumikawa, N.; Nishikori, S.; Vestergaard, M.; Hamada, T.; Hagihara, Y.; Yumoto, N.; Shiraki, K.; Takagi, M.
Effect of phospholipids on conformational structure of bovine pancreatic trypsin inhibitor (BPTI) and its thermolabile mutants
Biopolymers
89
873-880
2008
Bos taurus
Zhang, Y.; Kouzuma, Y.; Miyaji, T.; Yonekura, M.
Purification, characterization, and cDNA cloning of a Bowman-Birk type trypsin inhibitor from Apios americana Medikus tubers
Biosci. Biotechnol. Biochem.
72
171-178
2008
Bos taurus
Kim, M.S.; Kim, Y.K.; Lee, D.H.; Seo, J.E.; Cho, K.H.; Eun, H.C.; Chung, J.H.
Acute exposure of human skin to ultraviolet or infrared radiation or heat stimuli increases mast cell numbers and tryptase expression in human skin in vivo
Br. J. Dermatol.
160
393-402
2009
Homo sapiens
Kashyap, R.S.; Nayak, A.R.; Deshpande, P.S.; Kabra, D.; Purohit, H.J.; Taori, G.M.; Daginawala, H.F.
Inter-alpha-trypsin inhibitor heavy chain 4 is a novel marker of acute ischemic stroke
Clin. Chim. Acta
402
160-163
2009
Homo sapiens
Morisawa, Y.; Kitamura, A.; Ujihara, T.; Zushi, N.; Kuzume, K.; Shimanouchi, Y.; Tamura, S.; Wakiguchi, H.; Saito, H.; Matsumoto, K.
Effect of heat treatment and enzymatic digestion on the B cell epitopes of cows milk proteins
Clin. Exp. Allergy
39
918-925
2009
Homo sapiens
Ghosh, S.
Interaction of trypsin with sodium dodecyl sulfate in aqueous medium: a conformational view
Colloids Surf. B Biointerfaces
66
178-186
2008
Bos taurus
Otsuka, M.; Fukui, Y.; Ozaki, Y.
Comparative evaluation of bioactivity of crystalline trypsin for drying by Fourier-transformed infrared spectroscopy
Colloids Surf. B Biointerfaces
69
194-200
2009
Sus scrofa
Stefanov, E.K.; Ferrage, J.M.; Parchim, N.F.; Lee, C.E.; Reginelli, A.D.; Tache, M.; Anderson, R.A.
Modification of the zone of polarizing activity signal by trypsin
Dev. Growth Differ.
51
123-133
2009
Bos taurus
Yaghmaei, M.; Hashemi, M.; Shikhzadeh, A.; Mokhtari, M.; Niazi, A.; Ghavami, S.
Serum trypsin inhibitory capacity in normal pregnancy and gestational diabetes mellitus
Diabetes Res. Clin. Pract.
84
201-204
2009
Bos taurus
Wu, Y.J.; Ling, Q.; Zhou, X.H.; Wang, Y.; Xie, H.Y.; Yu, J.R.; Zheng, S.S.
Urinary trypsin inhibitor attenuates hepatic ischemia-reperfusion injury by reducing nuclear factor-kappa B activation
HBPD INT
8
53-58
2009
Mus musculus
Itabashi, K.; Furuta, K.; Takahashi, T.; Ito, Y.; Katagiri, H.; Sato, K.; Kakita, A.; Watanabe, M.
Urinary trypsin inhibitor improves viability of the liver in brain-dead rats
Hepatogastroenterology
55
568-573
2008
Rattus norvegicus
Pilpel, N.; Nezer, I.; Applebaum, S.W.; Heifetz, Y.
Mating-increases trypsin in female Drosophila hemolymph
Insect Biochem. Mol. Biol.
38
320-330
2008
Drosophila melanogaster
Yang, L.; Fang, Z.; Dicke, M.; van Loon, J.J.; Jongsma, M.A.
The diamondback moth, Plutella xylostella, specifically inactivates Mustard Trypsin Inhibitor 2 (MTI2) to overcome host plant defence
Insect Biochem. Mol. Biol.
39
55-61
2009
Bos taurus, Plutella xylostella
Venancio, T.M.; Cristofoletti, P.T.; Ferreira, C.; Verjovski-Almeida, S.; Terra, W.R.
The Aedes aegypti larval transcriptome: a comparative perspective with emphasis on trypsins and the domain structure of peritrophins
Insect Mol. Biol.
18
33-44
2009
Aedes aegypti (Q16TL8), Aedes aegypti
Ramos, V.d.a..S.; Silva, G.d.e..S.; Freire, M.G.; Machado, O.L.; Parra, J.R.; Macedo, M.L.
Purification and characterization of a trypsin inhibitor from Plathymenia foliolosa seeds
J. Agric. Food Chem.
56
11348-11355
2008
Bos taurus
Amorim, T.M.; Macedo, L.L.; Uchoa, A.F.; Oliveira, A.S.; Pitanga, J.C.; Macedo, F.P.; Santos, E.A.; de Sales, M.P.
Proteolytic digestive enzymes and peritrophic membranes during the development of Plodia interpunctella (Lepidoptera: Piralidae): targets for the action of soybean trypsin inhibitor (SBTI) and chitin-binding vicilin (EvV)
J. Agric. Food Chem.
56
7738-7745
2008
Plodia interpunctella
Botelho-Junior, S.; Siqueira-Junior, C.L.; Jardim, B.C.; Machado, O.L.; Neves-Ferreira, A.G.; Perales, J.; Jacinto, T.
Trypsin inhibitors in passion fruit (Passiflora f. edulis flavicarpa) leaves: accumulation in response to methyl jasmonate, mechanical wounding, and herbivory
J. Agric. Food Chem.
56
9404-9409
2008
Diatraea saccharalis
Taie, S.; Ueki, M.; Chujo, K.; Asaga, T.; Iwanaga, Y.; Ono, J.; Maekawa, N.
Urinary trypsin inhibitor ameliorates renal tissue oxygenation after ischemic reperfusion in rats
J. Anesth.
22
149-154
2008
Rattus norvegicus
Ramos, J.J.; Loste, A.; Ferrer, L.M.; Fernandez, A.; Castro, N.; Ortin, A.; Verde, M.T.; Argueello, A.; Figueras, L.
Effect of addition of soybean trypsin inhibitor to colostrum on immunological status in goat kids
J. Anim. Physiol. Anim. Nutr. (Berl.)
94
93-98
2010
Capra hircus
Swanson, K.C.; Kelly, N.; Salim, H.; Wang, Y.J.; Holligan, S.; Fan, M.Z.; McBride, B.W.
Pancreatic mass, cellularity, and alpha-amylase and trypsin activity in feedlot steers fed diets differing in crude protein concentration
J. Anim. Sci.
86
909-915
2008
Bos taurus
Ohshima, Y.; Suzuki, Y.; Nakatani, A.; Nohara, D.
Refolding of fully reduced bovine pancreatic trypsin
J. Biosci. Bioeng.
106
345-349
2008
Bos taurus
Nicoli, R.; Rudaz, S.; Stella, C.; Veuthey, J.L.
Trypsin immobilization on an ethylenediamine-based monolithic minidisk for rapid on-line peptide mass fingerprinting studies
J. Chromatogr. A
1216
2695-2699
2009
Bos taurus
Tubio, G.; Pico, G.A.; Nerli, B.B.
Extraction of trypsin from bovine pancreas by applying polyethyleneglycol/sodium citrate aqueous two-phase systems
J. Chromatogr. B
877
115-120
2009
Bos taurus
Inoue, K.; Takano, H.; Yanagisawa, R.; Yoshikawa, T.
Protective effects of urinary trypsin inhibitor on systemic inflammatory response induced by lipopolysaccharide
J. Clin. Biochem. Nutr.
43
139-142
2008
Mus musculus
Muhlia-Almazan, A.; Sanchez-Paz, A.; Garcia-Carreno, F.L.
Invertebrate trypsins: a review
J. Comp. Physiol. B
178
655-672
2008
Astacus astacus, Asterias amurensis, Bos taurus, Musca domestica, Penaeus japonicus, Rhyzopertha dominica, Sesamia nonagrioides, Triatoma infestans, Penaeus paulensis, Diatraea saccharalis, Cancer pagurus, Rhynchophorus ferrugineus, Triops sp., Diaprepes abbreviatus (O76498), Stomoxys calcitrans (O76519), Stomoxys calcitrans (O76520), Aedes aegypti (P29786), Manduca sexta (P35045), Lepeophtheirus salmonis (Q7YSS9), Penaeus vannamei (Q9TY16)
Kowalik-Jankowska, T.; Biega, L.; Kuczer, M.; Konopi?ska, D.
Copper(II) complexes of Neobelliera bullata Trypsin Modulating Oostatic Factor and its analogues
J. Inorg. Biochem.
102
1615-1622
2008
Sarcophaga bullata
Jung, H.J.; Jeong, K.S.; Lee, D.G.
Effective antibacterial action of tat (47-58) by increased uptake into bacterial cells in the presence of trypsin
J. Microbiol. Biotechnol.
18
990-996
2008
Bos taurus
Page, M.J.; Carrell, C.J.; Di Cera, E.
Engineering protein allostery: 1.05 A resolution structure and enzymatic properties of a Na+-activated trypsin
J. Mol. Biol.
378
666-672
2008
Streptomyces griseus
Sun, Y.; Chen, M.Y.; Zhao, C.; An, K.N.; Amadio, P.C.
The effect of hyaluronidase, phospholipase, lipid solvent and trypsin on the lubrication of canine flexor digitorum profundus tendon
J. Orthop. Res.
26
1225-1229
2008
Sus scrofa
Brzozowski, K.; Majewski, R.; Jaskiewicz, A.; Legowska, A.; Klaudel, L.; Rodziewicz-Motowidlo, S.; Rolka, K.
Conformational studies of [Abu(3, 11)]-SFTI-1, an analogue of the trypsin inhibitor isolated from sunflower seeds
J. Pept. Sci.
14
911-916
2008
Bos taurus
Bania, J.; Kubiak, A.; Wojtachnio, K.; Polanowski, A.
Pancreatic secretory trypsin inhibitor acts as an effective inhibitor of cysteine proteinases gingipains from Porphyromonas gingivalis
J. Periodont. Res.
43
232-236
2008
Bos taurus
Kalli, A.; Hakansson, K.
Comparison of the electron capture dissociation fragmentation behavior of doubly and triply protonated peptides from trypsin, Glu-C, and chymotrypsin digestion
J. Proteome Res.
7
2834-2844
2008
Bos taurus
Kiser, J.Z.; Post, M.; Wang, B.; Miyagi, M.
Streptomyces erythraeus trypsin for proteomics applications
J. Proteome Res.
8
1810-1817
2009
Sus scrofa, Saccharopolyspora erythraea (Q54137), Saccharopolyspora erythraea
Petritis, B.; Qian, W.J.; Camp, D.; Smith, R.
A simple procedure for effective quenching of trypsin activity and prevention of 18O-labeling back-exchange
J. Proteome Res.
8
2157-2163
2009
Sus scrofa
Demaude, J.; Leveque, M.; Chaumaz, G.; Eutamene, H.; Fioramonti, J.; Bueno, L.; Ferrier, L.
Acute stress increases colonic paracellular permeability in mice through a mast cell-independent mechanism: Involvement of pancreatic trypsin
Life Sci.
84
847-852
2009
Mus musculus
Nobuoka, T.; Mizuguchi, T.; Oshima, H.; Shibata, T.; Kaji, S.; Nagayama, M.; Meguro, M.; Mitaka, T.; Hirata, K.
Impaired liver regeneration with humoral and genetic disturbances in urinary trypsin inhibitor-deficient mice
Liver Int.
29
979-987
2009
Mus musculus
Sha, H.; Ma, Q.; Jha, R.K.
Trypsin is the culprit of multiple organ injury with severe acute pancreatitis
Med. Hypotheses
72
180-182
2009
Rattus norvegicus
McEuen, A.R.; Walls, A.F.
Purification and characterization of mast cell tryptase and chymase from human tissues
Methods Mol. Med.
138
299-317
2008
Homo sapiens
Zhang, B.; Wang, D.F.; Fan, Y.; Zhang, L.; Luo, Y.
Affinity purification of trypsin inhibitor with anti-Aspergillus flavus activity from cultivated and wild soybean
Mycopathologia
167
163-171
2009
Sus scrofa
Koistinen, H.; Koistinen, R.; Zhang, W.M.; Valmu, L.; Stenman, U.H.
Nexin-1 inhibits the activity of human brain trypsin
Neuroscience
160
97-102
2009
Homo sapiens
Chaudhary, N.S.; Shee, C.; Islam, A.; Ahmad, F.; Yernool, D.; Kumar, P.; Sharma, A.K.
Purification and characterization of a trypsin inhibitor from Putranjiva roxburghii seeds
Phytochemistry
69
2120-2126
2008
Bos taurus
Christy, L.A.; Arvinth, S.; Saravanakumar, M.; Kanchana, M.; Mukunthan, N.; Srikanth, J.; Thomas, G.; Subramonian, N.
Engineering sugarcane cultivars with bovine pancreatic trypsin inhibitor (aprotinin) gene for protection against top borer (Scirpophaga excerptalis Walker)
Plant Cell Rep.
28
175-184
2009
Scirpophaga excerptalis
Hernandez-Nistal, J.; Martin, I.; Jimenez, T.; Dopico, B.; Labrador, E.
Two cell wall Kunitz trypsin inhibitors in chickpea during seed germination and seedling growth
Plant Physiol. Biochem.
47
181-187
2009
Bos taurus
Zhang, X.; Wang, H.; Ng, T.B.
Isolation and characterization of a novel trypsin inhibitor from fresh lily bulbs
Planta Med.
74
546-550
2008
Bos taurus
Islam, M.M.; Sohya, S.; Noguchi, K.; Yohda, M.; Kuroda, Y.
Crystal structure of an extensively simplified variant of bovine pancreatic trypsin inhibitor in which over one-third of the residues are alanines
Proc. Natl. Acad. Sci. USA
105
15334-15339
2008
Bos taurus
Kim, B.C.; Lopez-Ferrer, D.; Lee, S.M.; Ahn, H.K.; Nair, S.; Kim, S.H.; Kim, B.S.; Petritis, K.; Camp, D.G.; Grate, J.W.; Smith, R.D.; Koo, Y.M.; Gu, M.B.; Kim, J.
Highly stable trypsin-aggregate coatings on polymer nanofibers for repeated protein digestion
Proteomics
9
1893-1900
2009
Bos taurus
Tsujimura, S.; Saito, K.; Nakayamada, S.; Tanaka, Y.
Bolus infusion of human urinary trypsin inhibitor improves intractable interstitial pneumonia in patients with connective tissue diseases
Rheumatology
47
907-913
2008
Homo sapiens
Liu, T.; Wang, S.; Chen, G.
Immobilization of trypsin on silica-coated fiberglass core in microchip for highly efficient proteolysis
Talanta
77
1767-1773
2009
Bos taurus
Mattson, K.J.; Devlin, B.R.; Loskutoff, N.M.
Comparison of a recombinant trypsin with the porcine pancreatic extract on sperm used for the in vitro production of bovine embryos
Theriogenology
69
724-727
2008
Bos taurus, Sus scrofa
Larsen, A.K.; Seternes, O.M.; Larsen, M.; Aasmoe, L.; Bang, B.
Salmon trypsin stimulates the expression of interleukin-8 via protease-activated receptor-2
Toxicol. Appl. Pharmacol.
230
276-282
2008
Salmo salar
Wee, Y.M.; Kim, S.C.; Koo, S.K.; Kim, Y.H.; Jung, E.J.; Choi, M.Y.; Park, Y.H.; Park, K.T.; Lim, D.G.; Han, D.J.
Improved islet yields after purification following the novel endogenous trypsin inhibitor and histidine-tryptophan-ketoglutarate treatment in pigs
Transplant. Proc.
40
2585-2587
2008
Sus scrofa
Carr, M.N.; Torres, S.M.; Koch, S.N.; Reiter, L.V.
Investigation of the pruritogenic effects of histamine, serotonin, tryptase, substance P and interleukin-2 in healthy dogs
Vet. Dermatol.
20
105-110
2009
Homo sapiens
Tomar, S.; Patil, D.N.; Datta, M.; Tapas, S.; Preeti, S.; Chaudhary, A.; Sharma, A.K.; Tomar, S.; Kumar, P.
Crystallization and preliminary X-ray diffraction analysis of the complex of Kunitz-type tamarind trypsin inhibitor and porcine pancreatic trypsin
Acta Crystallogr. Sect. F
65
1179-1181
2009
Sus scrofa
Macedo, M.L.; Durigan, R.A.; da Silva, D.S.; Marangoni, S.; Freire, M.G.; Parra, J.R.
Adenanthera pavonina trypsin inhibitor retard growth of Anagasta kuehniella (Lepidoptera: Pyralidae)
Arch. Insect Biochem. Physiol.
73
213-231
2010
Ephestia kuehniella, Spodoptera frugiperda, Diatraea saccharalis, Anticarsia gemmatalis, Sitotroga cerealella, Corcyra cephalonica
Marcuschi, M.; Esposito, T.S.; Machado, M.F.; Hirata, I.Y.; Machado, M.F.; Silva, M.V.; Carvalho, L.B.; Oliveira, V.; Bezerra, R.S.
Purification, characterization and substrate specificity of a trypsin from the Amazonian fish tambaqui (Colossoma macropomum)
Biochem. Biophys. Res. Commun.
396
667-673
2010
Colossoma macropomum
Fang, E.F.; Wong, J.H.; Bah, C.S.; Lin, P.; Tsao, S.W.; Ng, T.B.
Bauhinia variegata var. variegata trypsin inhibitor: from isolation to potential medicinal applications
Biochem. Biophys. Res. Commun.
396
806-811
2010
Homo sapiens
Appavou, M.S.; Gibrat, G.; Bellissent-Funel, M.C.
Temperature dependence on structure and dynamics of Bovine Pancreatic Trypsin Inhibitor (BPTI): a neutron scattering study
Biochim. Biophys. Acta
1794
1398-1406
2009
Bos taurus
Wu, P.; Weisell, J.; Pakkala, M.; Peraekylae, M.; Zhu, L.; Koistinen, R.; Koivunen, E.; Stenman, U.H.; Naervaenen, A.; Koistinen, H.
Identification of novel peptide inhibitors for human trypsins
Biol. Chem.
391
283-293
2010
Homo sapiens
Iyaguchi, D.; Kawano, S.; Takada, K.; Toyota, E.
Structural basis for the design of novel Schiff base metal chelate inhibitors of trypsin
Bioorg. Med. Chem.
18
2076-2080
2010
Bos taurus
Gaber, A.; Johansson, M.; Stenman, U.H.; Hotakainen, K.; Ponten, F.; Glimelius, B.; Bjartell, A.; Jirstroem, K.; Birgisson, H.
High expression of tumour-associated trypsin inhibitor correlates with liver metastasis and poor prognosis in colorectal cancer
Br. J. Cancer
100
1540-1548
2009
Homo sapiens
Noguchi, H.; Ueda, M.; Hayashi, S.; Kobayashi, N.; Okitsu, T.; Iwanaga, Y.; Nagata, H.; Liu, X.; Kamiya, H.; Levy, M.F.; Matsumoto, S.
Comparison of trypsin inhibitors in preservation solution for islet isolation
Cell Transplant.
18
541-547
2009
Sus scrofa
Silva, L.B.; Reis, A.P.; Pereira, E.J.; Oliveira, M.G.; Guedes, R.N.
Partial purification and characterization of trypsin-like proteinases from insecticide-resistant and -susceptible strains of the maize weevil, Sitophilus zeamais
Comp. Biochem. Physiol. B
155
12-19
2010
Sitophilus zeamais
Stefansson, B.; Helgadottir, L.; Olafsdottir, S.; Gudmundsdottir, A.; Bjarnason, J.B.
Characterization of cold-adapted Atlantic cod (Gadus morhua) trypsin I--kinetic parameters, autolysis and thermal stability
Comp. Biochem. Physiol. B
155
186-194
2010
Gadus morhua
Qi, R.F.; Liu, Z.X.; Xu, S.Q.; Zhang, L.; Shao, X.X.; Chi, C.W.
Small peptides derived from the Lys active fragment of the mung bean trypsin inhibitor are fully active against trypsin
FEBS J.
277
224-232
2010
Bos taurus
Kanno, G.; Yamaguchi, T.; Kishimura, H.; Yamaha, E.; Saeki, H.
Purification and characteristics of trypsin from masu salmon (Oncorhynchus masou) cultured in fresh-water
Fish Physiol. Biochem.
36
637-645
2009
Oncorhynchus masou
Barkia, A.; Bougatef, A.; Nasri, R.; Fetoui, E.; Balti, R.; Nasri, M.
Trypsin from the viscera of Bogue (Boops boops): isolation and characterisation
Fish Physiol. Biochem.
36
893-902
2009
Boops boops
Kamaci, H.O.; Suzer, C.; Coban, D.; Saka, S.; Firat, K.
Organogenesis of exocrine pancreas in sharpsnout sea bream (Diplodus puntazzo) larvae: characterization of trypsin expression
Fish Physiol. Biochem.
36
993-1000
2010
Diplodus puntazzo
Balti, R.; Barkia, A.; Bougatef, A.; Ktari, N.; Nasri, M.
A heat-stable trypsin from the hepatopancreas of the cuttlefish (Sepia officinalis): Purification and characterisation
Food Chem.
113
146-154
2009
Sepia officinalis
Fuchise, T.; Kishimura, H.; Sekizaki, H.; Nonami, Y.; Kanno, G.; Klomklao, S.; Benjakul, S.; Chun, B.
Purification and characteristics of trypsins from cold-zone fish, Pacific cod (Gadus macrocephalus) and saffron cod (Eleginus gracilis)
Food Chem.
116
611-616
2009
Gadus macrocephalus, Eleginus gracilis
Jellouli, K.; Bougatef, A.; Daassi, D.; Balti, R.; Barkia, A.; Nasri, M.
New alkaline trypsin from the intestine of Grey triggerfish (Balistes capriscus) with high activity at low temperature: purification and characterisation
Food Chem.
116
644-650
2009
Balistes capriscus
Guerrero-Beltran, J.; Estrada-Giron, Y.; Swanson, B.; Barbosa-Canovas, G.
Pressure and temperature combination for inactivation of soymilk trypsin inhibitors
Food Chem.
116
676-679
2009
Bos taurus
Khantaphant, S.; Benjakul, S.
Purification and characterization of trypsin from the pyloric caeca of brownstripe red snapper (Lutjanus vitta)
Food Chem.
120
658-664
2010
Lutjanus vitta
Klomklao, S.; Kishimura, H.; Benjakul, S.
Trypsin from the pyloric ceca of pectoral rattail (Coryphaenoides pectoralis): purification and characterization
J. Agric. Food Chem.
57
7097-7103
2009
Albatrossia pectoralis
Bougatef, A.; Balti, R.; Nasri, R.; Jellouli, K.; Souissi, N.; Nasri, M.
Biochemical properties of anionic trypsin acting at high concentration of NaCl purified from the intestine of a carnivorous fish: smooth hound (Mustelus mustelus)
J. Agric. Food Chem.
58
5763-5769
2010
Mustelus mustelus
Torbica, A.M.; Z?ivancev, D.R.; Nikolic, Z.T.; Dordevic, V.B.; Nikolovski, B.G.
Advantages of the lab-on-a-chip method in the determination of the Kunitz trypsin inhibitor in soybean varieties
J. Agric. Food Chem.
58
7980-7985
2010
Bos taurus
Fang, E.F.; Wong, J.H.; Ng, T.B.
Thermostable Kunitz trypsin inhibitor with cytokine inducing, antitumor and HIV-1 reverse transcriptase inhibitory activities from Korean large black soybeans
J. Biosci. Bioeng.
109
211-217
2010
Bos taurus
Pereira, H.J.; Salgado, M.C.; Oliveira, E.B.
Immobilized analogues of sunflower trypsin inhibitor-1 constitute a versatile group of affinity sorbents for selective isolation of serine proteases
J. Chromatogr. B
877
2039-2044
2009
Bos taurus
Hashemi, M.; Mehrabifar, H.; Daliri, M.; Ghavami, S.
Adenosine deaminase activity, trypsin inhibitory capacity and total antioxidant capacity in psoriasis
J. Eur. Acad. Dermatol. Venereol.
24
329-334
2010
Homo sapiens
Wati, R.K.; Theppakorn, T.; Benjakul, S.; Rawdkuen, S.
Trypsin inhibitor from 3 legume seeds: fractionation and proteolytic inhibition study
J. Food Sci.
75
C223-C228
2010
Bos taurus
Avanzo, P.; Sabotic, J.; Anzlovar, S.; Popovic, T.; Leonardi, A.; Pain, R.H.; Kos, J.; Brzin, J.
Trypsin-specific inhibitors from the basidiomycete Clitocybe nebularis with regulatory and defensive functions
Microbiology
155
3971-3981
2009
Homo sapiens
Garcia Boy, R.; Mier, W.; Nothelfer, E.M.; Altmann, A.; Eisenhut, M.; Kolmar, H.; Tomaszowski, M.; Kraemer, S.; Haberkorn, U.
Sunflower trypsin inhibitor 1 derivatives as molecular scaffolds for the development of novel peptidic radiopharmaceuticals
Mol. Imaging Biol.
12
377-385
2009
Bos taurus
SantAnna, M.; Diaz-Albiter, H.; Mubaraki, M.; Dillon, R.; Bates, P.
Inhibition of trypsin expression in Lutzomyia longipalpis using RNAi enhances the survival of Leishmania
Parasit. Vectors
2
62
2009
Lutzomyia longipalpis
Prasad, E.R.; Dutta-Gupta, A.; Padmasree, K.
Purification and characterization of a Bowman-Birk proteinase inhibitor from the seeds of black gram (Vigna mungo)
Phytochemistry
71
363-372
2010
Bos taurus
Lahti, J.; Silverman, A.; Cochran, J.
Interrogating and predicting tolerated sequence diversity in protein folds: Application to E. elaterium trypsin inhibitor-II cystine-knot miniprotein
PLoS Comput. Biol.
5
e1000499
2009
Sus scrofa
Oliveira, A.S.; Migliolo, L.; Aquino, R.O.; Ribeiro, J.K.; Macedo, L.L.; Bemquerer, M.P.; Santos, E.A.; Kiyota, S.; de Sales, M.P.
Two Kunitz-type inhibitors with activity against trypsin and papain from Pithecellobium dumosum seeds: purification, characterization, and activity towards pest insect digestive enzyme
Protein Pept. Lett.
16
1526-1532
2009
Ceratitis capitata, Plodia interpunctella, Zabrotes subfasciatus
Darani, H.Y.; Doenhoff, M.J.
Anomalous immunogenic properties of serine proteases
Scand. J. Immunol.
70
384-388
2009
Sus scrofa
Kim, D.S.; Lee, K.J.; Kim, J.B.; Kim, S.H.; Song, J.Y.; Seo, Y.W.; Lee, B.M.; Kang, S.Y.
Identification of Kunitz trypsin inhibitor mutations using SNAP markers in soybean mutant lines
Theor. Appl. Genet.
121
751-760
2010
Sus scrofa
Uesugi, Y.; Usuki, H.; Arima, J.; Iwabuchi, M.; Hatanaka, T.
Molecular dissection of Streptomyces trypsin on substrate recognition
Biochim. Biophys. Acta
1814
1295-1304
2011
Streptomyces griseus, Streptomyces omiyaensis
Fuchise, T.; Kishimura, H.; Yang, Z.H.; Kojoma, M.; Toyota, E.; Sekizaki, H.
Atlantic cod trypsin-catalyzed peptide synthesis with inverse substrates as acyl donor components
Chem. Pharm. Bull.
58
484-487
2010
Gadus morhua
Cai, Q.F.; Jiang, Y.K.; Zhou, L.G.; Sun, L.C.; Liu, G.M.; Osatomi, K.; Cao, M.J.
Biochemical characterization of trypsins from the hepatopancreas of Japanese sea bass (Lateolabrax japonicus)
Comp. Biochem. Physiol. B
159
183-189
2011
Lateolabrax japonicus
Galaviz, M.A.; Garcia-Ortega, A.; Gisbert, E.; Lopez, L.M.; Gasca, A.G.
Expression and activity of trypsin and pepsin during larval development of the spotted rose snapper Lutjanus guttatus
Comp. Biochem. Physiol. B
161
9-16
2012
Lutjanus guttatus
Kanno, G.; Kishimura, H.; Ando, S.; Klomklao, S.; Nalinanon, S.; Benjakul, S.; Chun, B.; Saeki, H.
Structural properties of trypsin from cold-adapted fish, arabesque greenling (Pleurogrammus azonus)
Eur. Food Res. Technol.
232
381-388
2011
Pleurogrammus azonus (B3IYE4)
-
Kanno, G.; Kishimura, H.; Yamamoto, J.; Ando, S.; Shimizu, T.; Benjakul, S.; Klomklao, S.; Nalinanon, S.; Chun, B.; Saeki, H.
Cold-adapted structural properties of trypsins from walleye pollock (Theragra chalcogramma) and Arctic cod (Boreogadus saida)
Eur. Food Res. Technol.
233
963-972
2011
Gadus chalcogrammus (C4TP29), Boreogadus saida (D0G7G2)
Ben Khaled, H.; Jellouli, K.; Souissi, N.; Ghorbel, S.; Barkia, A.; Nasri, M.
Purification and characterization of three trypsin isoforms from viscera of sardinelle (Sardinella aurita)
Fish Physiol. Biochem.
37
123-133
2011
Sardinella aurita
Liu, C.H.; Shiu, Y.L.; Hsu, J.L.
Purification and characterization of trypsin from the pyloric ceca of orange-spotted grouper, Epinephelus coioides
Fish Physiol. Biochem.
38
837-848
2011
Epinephelus coioides, Epinephelus coioides (G9JKF3)
Wahlgren, W.Y.; Pal, G.; Kardos, J.; Porrogi, P.; Szenthe, B.; Patthy, A.; Graf, L.; Katona, G.
The catalytic aspartate is protonated in the Michaelis complex formed between trypsin and an in vitro evolved substrate-like inhibitor: a refined mechanism of serine protease action
J. Biol. Chem.
286
3587-3596
2011
Bos taurus
De, D.; Chakraborty, P.D.; Bhattacharyya, D.
Regulation of trypsin activity by peptide fraction of an aqueous extract of human placenta used as wound healer
J. Cell. Physiol.
226
2033-2040
2010
Homo sapiens
Kwong, K.; Nassenstein, C.; de Garavilla, L.; Meeker, S.; Undem, B.J.
Thrombin and trypsin directly activate vagal C-fibres in mouse lung via protease-activated receptor-1
J. Physiol.
588
1171-1177
2010
Bos taurus
Liebschner, D.; Dauter, M.; Brzuszkiewicz, A.; Dauter, Z.
On the reproducibility of protein crystal structures: five atomic resolution structures of trypsin
Acta Crystallogr. Sect. D
69
1447-1462
2013
Bos taurus (P00760), Bos taurus
Blankenship, E.; Vukoti, K.; Miyagi, M.; Lodowski, D.T.
Conformational flexibility in the catalytic triad revealed by the high-resolution crystal structure of Streptomyces erythraeus trypsin in an unliganded state
Acta Crystallogr. Sect. D
70
833-840
2014
Saccharopolyspora erythraea (P24664), Saccharopolyspora erythraea
Gardner, Q.A.; Younas, H.; Akhtar, M.
Studies on the regioselectivity and kinetics of the action of trypsin on proinsulin and its derivatives using mass spectrometry
Biochim. Biophys. Acta
1834
182-190
2013
Bos taurus
Atacan, K.; Oezacar, M.
Characterization and immobilization of trypsin on tannic acid modified Fe3O4 nanoparticles
Colloids Surf. B Biointerfaces
128
227-236
2015
Bos taurus
Zhou, L.; Ruan, M.; Cai, Q.; Liu, G.; Sun, L.; Su, W.; Cao, M.
Purification, characterization and cDNA cloning of a trypsin from the hepatopancreas of snakehead (Channa argus)
Comp. Biochem. Physiol. B
161
247-254
2012
Channa argus (G3LUK8), Channa argus
Bhagwat, S.S.; Larsen, A.K.; Winberg, J.O.; Seternes, O.M.; Bang, B.E.
Salmon and king crab trypsin stimulate interleukin-8 and matrix metalloproteinases via protease-activated receptor-2 in the skin keratinocytic HaCaT cell line
Food Chem. Toxicol.
69
303-311
2014
Salmo salar, Paralithodes camtschaticus (Q8WR10)
Unajak, S.; Meesawat, P.; Paemanee, A.; Areechon, N.; Engkagul, A.; Kovitvadhi, U.; Kovitvadhi, S.; Rungruangsak-Torrissen, K.; Choowongkomon, K.
Characterisation of thermostable trypsin and determination of trypsin isozymes from intestine of Nile tilapia (Oreochromis niloticus L.)
Food Chem.
134
1533-1541
2012
Oreochromis niloticus
Villalba-Villalba, A.G.; Ramirez-Suarez, J.C.; Valenzuela-Soto, E.M.; Sanchez, G.G.; Ruiz, G.C.; Pacheco-Aguilar, R.
Trypsin from viscera of vermiculated sailfin catfish, Pterygoplichthys disjunctivus, Weber, 1991: its purification and characterization
Food Chem.
141
940-945
2013
Pterygoplichthys disjunctivus
Khangembam, B.K.; Chakrabarti, R.
Trypsin from the digestive system of carp Cirrhinus mrigala: purification, characterization and its potential application
Food Chem.
175
386-394
2015
Cirrhinus mrigala
Lacerda, C.D.; Teixeira, A.E.; de Oliveira, J.S.; Silva, S.F.; Vasconcelos, A.V.; Gouveia, D.G.; da Silva, A.R.; Santoro, M.M.; dos Mares-Guia, M.L.; Santos, A.M.
Gamma trypsin: purification and physicochemical characterization of a novel bovine trypsin isoform
Int. J. Biol. Macromol.
70
179-186
2014
Bos taurus
Wang, Y.Q.; Zhang, H.M.
Effects of bisphenol S on the structures and activities of trypsin and pepsin
J. Agric. Food Chem.
62
11303-11311
2014
Sus scrofa
Haerteis, S.; Krappitz, A.; Krappitz, M.; Murphy, J.; Bertog, M.; Krueger, B.; Nacken, R.; Chung, H.; Hollenberg, M.; Knecht, W.; Bunnett, N.; Korbmacher, C.
Proteolytic activation of the human epithelial sodium channel by trypsin IV and trypsin I involves distinct cleavage sites
J. Biol. Chem.
289
19067-19078
2014
Homo sapiens
Valdez-Melchor, R.; Ezquerra-Brauer, J.; Cinco-Moroyoqui, F.; Castillo-Yanez, F.; Cardenas-Lopez, J.
Purification and partial characterization of trypsin from the viscera of tropical sierra (Scomberomorus Sierra) from the Gulf of California
J. Food Biochem.
37
694-701
2013
Scomberomorus sierra
-
Meng, Y.; Yuan, Y.; Zhu, Y.; Guo, Y.; Li, M.; Wang, Z.; Pu, X.; Jiang, L.
Effects of organic solvents and substrate binding on trypsin in acetonitrile and hexane media
J. Mol. Model.
19
3749-3766
2013
Sus scrofa (P00761)
Mao, Y.; Kunapuli, S.P.
Trypsin causes platelet activation independently of known protease-activated receptors
Thromb. Haemost.
110
1241-1249
2013
Sus scrofa
Rajapakse, S.; Ogiwara, K.; Takahashi, T.
Characterization and expression of trypsinogen and trypsin in medaka testis
Zool. Sci.
31
840-848
2014
Oryzias latipes
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