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Disease on EC 3.4.21.38 - coagulation factor XIIa

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Abducens Nerve Diseases
Factor XII deficiency and recurrent sixth nerve palsy.
Abnormalities, Multiple
Wasp sting anaphylaxis.
Abortion, Habitual
Coagulation factor XII activity, but not an associated common genetic polymorphism (46C/T),is linked to recurrent miscarriage.
Decreased Factor XII Activity is Associated with Recurrent IVF-ET Failure.
Factor XII (Hageman) deficiency in women with habitual abortion: new subpopulation of recurrent aborters?
Factor XII but not protein C, protein S, antithrombin III, or factor XIII is a predictor of recurrent miscarriage.
Factor XII deficiency in women with recurrent miscarriage.
Factor XII deficiency is strongly associated with primary recurrent abortions.
Fibrinolytic defects and recurrent miscarriage: a systematic review and meta-analysis.
Low-dose aspirin is effective for treatment of recurrent miscarriage in patients with decreased coagulation factor XII.
Role of coagulation factor XII in unexplained recurrent abortions in the Greek population.
The C46T polymorphism of the coagulation factor XII gene and idiopathic recurrent miscarriage.
Abortion, Spontaneous
Factor XII but not protein C, protein S, antithrombin III, or factor XIII is a predictor of recurrent miscarriage.
Factor XII congenital deficiency and early spontaneous abortion.
Recurrent reproductive wastage and immunologic factors.
Role of coagulation factor XII in unexplained recurrent abortions in the Greek population.
Abruptio Placentae
Factor XII deficiency and pregnancy.
Acidosis
Complement and contact activation in term neonates after fetal acidosis.
Acidosis, Lactic
In vitro activation of complement and contact system by lactic acidosis.
Activated Protein C Resistance
Factor XII deficiency is strongly associated with primary recurrent abortions.
Genetic determinants of hemostasis phenotypes in Spanish families.
The effects of transport temperature and time on routine and specialized coagulation assays.
Acute Coronary Syndrome
Activated factor 12 (FXIIa) predicts recurrent coronary events after an acute myocardial infarction.
Activated factor XII type A and B-type natriuretic peptide are complementary and incremental predictors of mortality in patients following admission with acute coronary syndrome.
Activated factor XII type A predicts long-term mortality in patients admitted with chest pain.
Acute coronary syndromes do not promote prolonged in vivo FXII-dependent prothrombotic activity.
Homozygosity for the C-->T polymorphism at nucleotide 46 in the 5' untranslated region of the factor XII gene protects from development of acute coronary syndrome.
Acute Lung Injury
[Acute lung injury as a consequence of fresh frozen plasma administration in a patient with factor XII deficiency.]
Adenoviridae Infections
Transient lupus anticoagulant associated with hypoprothrombinemia and factor XII deficiency following adenovirus infection.
Adrenocortical Hyperfunction
Further studies on the hypercoagulable state of patients with Cushing's syndrome.
Afibrinogenemia
Reaction of blood with artificial surfaces of hemodialyzers. Studies of human blood with platelet defects or coagulation factor deficiencies.
Alzheimer Disease
?-Amyloid Orchestrates Factor XII and Platelet Activation Leading to Endothelial Dysfunction and Abnormal Fibrinolysis in Alzheimer Disease.
Depletion of coagulation factor XII ameliorates brain pathology and cognitive impairment in Alzheimer's disease mice.
Hageman factor and its binding sites are present in senile plaques of Alzheimer's disease.
Interaction of factor XII and high molecular weight kininogen with cytokeratin 1 and gC1qR of vascular endothelial cells and with aggregated Abeta protein of Alzheimer's disease.
Interactions of ?-amyloid peptide with fibrinogen and coagulation factor XII may contribute to Alzheimer's disease.
Self-assembly of N-terminal Alzheimer's ?-amyloid and its inhibition.
The Alzheimer's disease peptide ?-amyloid promotes thrombin generation through activation of coagulation factor XII: comment.
The Alzheimer's disease peptide ?-amyloid promotes thrombin generation through activation of coagulation factor XII: reply.
The Alzheimer's disease peptide A? promotes thrombin generation through activation of coagulation factor XII.
Amyloidosis
Misfolded proteins activate factor XII in humans, leading to kallikrein formation without initiating coagulation.
The elusive physiologic role of Factor XII.
Anaphylaxis
Activation and consumption of Hageman factor in the anaphylactic shock of the rat.
Activation of human Hageman factor by a leukocytic protease.
Bradykinin generation by dialysis membranes: possible role in anaphylactic reaction.
Dextran-induced anaphylactoid reaction in man: altered reactivity of high molecular weight kininogen.
Plasma contact system activation drives anaphylaxis in severe mast cell-mediated allergic reactions.
Reduced aggregability of platelets in rat anaphylaxis.
The IgE-dependent release of a Hageman factor cleaving factor from human lung.
Anemia
[Circulating anticoagulant against factor XII in a patient with autoimmune hemolitic anemia (author's transl)]
Anemia, Hemolytic
Factor XII deficiency and von Willebrand's disease in a family of miniature poodle dogs.
Anemia, Refractory, with Excess of Blasts
Circulating anticoagulant against factor XII in smoldering leukemia.
Aneurysm
Differential Protein Expression in Serum of Abdominal Aortic Aneurysm Patients - A Proteomic Approach.
Angina Pectoris
Characterization of factor XII Tenri, a rare CRM-negative factor XII deficiency.
Angina, Stable
Acute coronary syndromes do not promote prolonged in vivo FXII-dependent prothrombotic activity.
Angina, Unstable
Activation of leukocytes and of the kallikrein-kinin system in patients with unstable angina pectoris.
Acute coronary syndromes do not promote prolonged in vivo FXII-dependent prothrombotic activity.
Angioedema
Angioedema attacks in patients with hereditary angioedema: Local manifestations of a systemic activation process.
Angioedema attacks related to endometrial hyperplasia in a case of estrogen-dependent factor XII hereditary angioedema.
Angioedema Phenotypes: Disease Expression and Classification.
Angioedema.
Are complement deficiencies really rare? Overview on prevalence, clinical importance and modern diagnostic approach.
Complement, Kinins, and Hereditary Angioedema: Mechanisms of Plasma Instability when C1 Inhibitor is Absent.
Deficiency of plasminogen activator inhibitor 2 in plasma of patients with hereditary angioedema with normal C1 inhibitor levels.
Factor XII mutations, estrogen-dependent inherited angioedema, and related conditions.
Genetic analysis of Factor XII and bradykinin catabolic enzymes in a family with estrogen-dependent inherited angioedema.
Hereditary angioedema in childhood: an approach to management.
Hereditary angioedema with normal C1 inhibitor and factor XII mutation: a series of 57 patients from the French National Center of Reference for Angioedema.
Impaired control of the contact system in hereditary angioedema with normal C1-inhibitor.
Lisinopril-Induced Angioedema in a Patient with Plasma Prekallikrein Deficiency.
Measurement of Bradykinin Formation and Degradation in Blood Plasma: Relevance for Acquired Angioedema Associated With Angiotensin Converting Enzyme Inhibition and for Hereditary Angioedema Due to Factor XII or Plasminogen Gene Variants.
Novel duplication in the F12 gene in a patient with recurrent angioedema.
Novelties in the Diagnosis and Treatment of Angioedema.
Prekallikrein activation and high-molecular-weight kininogen consumption in hereditary angioedema.
Repeated attacks of type III hereditary angioedema with factor XII mutation during pregnancy.
Zinc-dependent contact system activation induces vascular leakage and hypotension in rodents.
[Gender aspects in angioedema].
Angioedemas, Hereditary
"Nuts and Bolts" of Laboratory Evaluation of Angioedema.
A mechanism for hereditary angioedema with normal C1-inhibitor: an inhibitory regulatory role for the factor XII heavy chain.
An investigational RNAi therapeutic targeting Factor XII (ALN-F12) for the treatment of hereditary angioedema.
Angioedema attacks related to endometrial hyperplasia in a case of estrogen-dependent factor XII hereditary angioedema.
Angioedema Phenotypes: Disease Expression and Classification.
Angioedema.
Bradykinin: Inflammatory Product of the Coagulation System.
Characterization of a partial exon 9/intron 9 deletion in the coagulation factor XII gene (F12) detected in two Turkish families with hereditary angioedema and normal C1 inhibitor.
Coagulation Factor XII Gene Mutation in Brazilian Families with Hereditary Angioedema with Normal C1 Inhibitor.
Cytokine and estrogen stimulation of endothelial cells augments activation of the prekallikrein-high molecular weight kininogen complex: Implications for hereditary angioedema.
Defective glycosylation of coagulation factor XII underlies hereditary angioedema type III.
Deficiency of plasminogen activator inhibitor 2 in plasma of patients with hereditary angioedema with normal C1 inhibitor levels.
Definition and classification of hereditary angioedema.
Design and characterization of ?1-antitrypsin variants for treatment of contact system-driven thromboinflammation.
Factor XII gene missense mutation Thr328Lys in an Arab family with hereditary angioedema type III.
Factor XII mutations, estrogen-dependent inherited angioedema, and related conditions.
Factor XII(a) inhibitors: a review of the patent literature.
Genetic Variation of Kallikrein-Kinin System and Related Genes in Patients With Hereditary Angioedema.
Hereditary angioedema caused by missense mutations in the factor XII gene: clinical features, trigger factors, and therapy.
Hereditary angioedema with normal C1 inhibitor activity including hereditary angioedema with coagulation factor XII gene mutations.
Hereditary angioedema with normal C1 inhibitor and factor XII mutation: a series of 57 patients from the French National Center of Reference for Angioedema.
Hereditary angioedema.
Impaired control of the contact system in hereditary angioedema with normal C1-inhibitor.
Increased activity of coagulation factor XII (Hageman factor) causes hereditary angioedema type III.
Interactions of C1(-)-inhibitors from normal persons and patients with type II hereditary angioneurotic edema with purified activated Hageman factor (factor XIIa).
Kallikrein-kinin system and fibrinolysis in hereditary angioedema due to factor XII gene mutation Thr309Lys.
Management of upper airway edema caused by hereditary angioedema.
Measurement of Bradykinin Formation and Degradation in Blood Plasma: Relevance for Acquired Angioedema Associated With Angiotensin Converting Enzyme Inhibition and for Hereditary Angioedema Due to Factor XII or Plasminogen Gene Variants.
Missense mutation Thr309Lys in the coagulation factor XII gene in a Spanish family with hereditary angioedema type III.
Missense mutations in the coagulation factor XII (Hageman factor) gene in hereditary angioedema with normal C1 inhibitor.
Mutation of the angiopoietin-1 gene (ANGPT1) associates with a new type of hereditary angioedema.
Novel duplication in the F12 gene in a patient with recurrent angioedema.
Pathways of kinin formation and role in allergic diseases.
Peptide Macrocycle Inhibitor of Coagulation Factor XII with Subnanomolar Affinity and High Target Selectivity.
Plasma kinin activation in tranexamic acid treated patients with hereditary angioneurotic edema.
Plasma levels of C1- inhibitor complexes and cleaved C1- inhibitor in patients with hereditary angioneurotic edema.
Plasmin is a natural trigger for bradykinin production in patients with hereditary angioedema with factor XII mutations.
Prekallikrein activation and high-molecular-weight kininogen consumption in hereditary angioedema.
Recurrent angioedema and the threat of asphyxiation.
Repeated attacks of type III hereditary angioedema with factor XII mutation during pregnancy.
Screening for Plasminogen Mutations in Hereditary Angioedema Patients.
sgp120 and the contact system in hereditary angioedema: A diagnostic tool in HAE with normal C1 inhibitor.
Studies of C1 inactivator-plasma kallikrein complexes in purified systems and in plasma.
Studies of the mechanisms of bradykinin generation in hereditary angioedema plasma.
Successful perinatal management of hereditary angioedema with normal C1 esterase inhibitor and factor XII mutation using C1 esterase inhibitor therapy.
The bradykinin-forming cascade and its role in hereditary angioedema.
The contact activation and kallikrein/kinin systems: pathophysiologic and physiologic activities.
The FXII c.-4T>C Polymorphism as a Disease Modifier in Patients With Hereditary Angioedema Due to the FXII p.Thr328Lys Variant.
Variability in purified dysfunctional C1(-)-inhibitor proteins from patients with hereditary angioneurotic edema. Functional and analytical gel studies.
[Gender aspects in angioedema].
Antiphospholipid Syndrome
Acquired factor XII deficiency in a woman with recurrent pregnancy loss: working on a differential diagnosis in a single case.
Antibodies to factor XII and recurrent fetal loss in patients with the anti-phospholipid syndrome.
Antibodies to factor XII are distinct from antibodies to prothrombin in patients with the anti-phospholipid syndrome.
Antibodies to factor XII: a possible predictive marker for recurrent foetal loss.
beta 2 glycoprotein-I inhibits factor XII activation on triglyceride rich lipoproteins: the effect of antibodies from plasma of patients with antiphospholipid syndrome.
Chronic thromboembolic pulmonary hypertension is a clot you cannot swat.
Reduced factor XII levels in patients with the antiphospholipid syndrome are associated with antibodies to factor XII.
The antigenic binding site(s) of antibodies to factor XII associated with the antiphospholipid syndrome.
The contact system.
Antithrombin III Deficiency
Cardiopulmonary bypass in patients with pre-existing coagulopathy.
Clinical Outcomes after Biologic Graft Use for the Creation of Blalock-Taussig Shunt in Critically Ill Patients with Thrombophilia.
Arthritis, Gouty
Classic gout in Hageman factor (Factor XII) deficiency.
Hageman factor and acute gouty arthritis.
Inflammatory process in acute gouty arthritis. 3. Vascular permeability-enhancing activity in normal human synovial fluid; induction by Hageman factor activators; and inhibition by Hageman factor antiserum.
Participation of Hageman factor dependent pathways in human disease states.
THE INFLAMMATORY PROCESS IN ACUTE GOUTY ARTHRITIS. I. ACTIVATION OF HAGEMAN FACTOR BY SODIUM URATE CRYSTALS.
The inflammatory process in acute gouty arthritis. II. The presence of Hageman factor and plasma thromboplastin antecedent in synovial fluid.
Arthritis, Rheumatoid
Activated factor XII in rheumatoid arthritis.
Hageman factor (factor XII) activity in synovial fluid of rheumatoid arthritis patients and its possible pathogenic significance.
The Coagulation Factors Fibrinogen, Thrombin, and Factor XII in Inflammatory Disorders-A Systematic Review.
Arthus Reaction
The Arthus reaction in cats deficient in Hageman factor (factor XII).
Ataxia Telangiectasia
Hageman factor deficiency in ataxia telangiectasia.
Atherosclerosis
Activated factor XII levels and factor XII 46C>T genotype in relation to coronary artery calcification in patients with type 1 diabetes and healthy subjects.
Coagulation factor XII induces pro-inflammatory cytokine responses in macrophages and promotes atherosclerosis in mice.
Atypical Hemolytic Uremic Syndrome
A case of atypical hemolytic uremic syndrome due to anti-factor H antibody in a patient presenting with a factor XII deficiency identified two novel mutations.
Bacteremia
Activation and inhibition of Hageman factor-dependent pathways and the complement system in uncomplicated bacteremia or bacterial shock.
CpaA Is a Glycan-Specific Adamalysin-like Protease Secreted by Acinetobacter baumannii That Inactivates Coagulation Factor XII.
Plasma kallikrein and Hageman factor in Gram-negative bacteremia.
The contact system contributes to hypotension but not disseminated intravascular coagulation in lethal bacteremia. In vivo use of a monoclonal anti-factor XII antibody to block contact activation in baboons.
Bacterial Infections
Binding and activation of human plasma kinin-forming system on the cell walls of Candida albicans and Candida tropicalis.
Posttraumatic acute cholecystitis. Relationship to the initial trauma.
Blood Coagulation Disorders
Surgical management in the patient with congenital factor XII deficiency. Report of a case.
Boutonneuse Fever
Depletion of Hageman factor in acute phase of boutonneuse fever.
Bradycardia
Acute hypotension due to platelet serotonin-induced chemoreflexes after intravenous injection of dextran sulfate in the rabbit.
Brain Edema
Alleviation of secondary brain injury, posttraumatic inflammation, and brain edema formation by inhibition of factor XIIa.
Brain Injuries
Alleviation of secondary brain injury, posttraumatic inflammation, and brain edema formation by inhibition of factor XIIa.
Pharmacological regulation of factor XII activation may be a new target to control pathological coagulation.
Brain Injuries, Traumatic
Amelioration of Cognitive and Behavioral Deficits after Traumatic Brain Injury in Coagulation Factor XII Deficient Mice.
Ischemic stroke and traumatic brain injury: the role of the kallikrein-kinin system.
Targeting Coagulation Factor XII as a Novel Therapeutic Option in Brain Trauma.
Traumatic brain injury: Factor XII inhibition is neuroprotective after traumatic brain injury in mice.
Brain Ischemia
COU254, a specific 3-carboxamide-coumarin inhibitor of coagulation factor XII, does not protect mice from acute ischemic stroke.
Molecular mechanisms of thrombus formation in ischemic stroke: novel insights and targets for treatment.
Selective factor XIIa inhibition attenuates silent brain ischemia: application of molecular imaging targeting coagulation pathway.
Targeting coagulation factor XII provides protection from pathological thrombosis in cerebral ischemia without interfering with hemostasis.
Budd-Chiari Syndrome
Activation of Hageman factor and initiation of hepatic vein thrombosis in the hyperlipemic rat.
Factor XII deficiency acquired by orthotopic liver transplantation: case report and review of the literature.
Carcinoma
[Effect of compound Chinese drug bailong on the expression of tumor suppressor genes and relationship with prekallikrein activator signal pathway in human gastric carcinoma BGC82-3 cell line]
Carcinoma, Hepatocellular
Factor XII-induced mitogenesis is mediated via a distinct signal transduction pathway that activates a mitogen-activated protein kinase.
Interleukin-6 downregulates factor XII production by human hepatoma cell line (HepG2).
Carcinoma, Ovarian Epithelial
The interaction of coagulation factor XII and monocyte/macrophages mediating peritoneal metastasis of epithelial ovarian cancer.
Cardiovascular Diseases
A new enzyme-linked immunosorbent assay recognizing both rat and human activated coagulation Factor XII (FXIIa).
Development of aptamer oligonucleotides as anticoagulants and antithrombotics for cardiovascular diseases: current status.
Impact of biomarkers for endothelial dysfunction and procoagulant state on 10-year cardiovascular risk in Type?2 diabetes(1).
Inhibition of Platelet Adhesion from Surface Modified Polyurethane Membranes.
Lower factor XII activity is a risk marker rather than a risk factor for cardiovascular disease: a rebuttal.
The Functional Promoter Polymorphism of the Coagulation Factor XII Gene is not Associated With Peripheral Arterial Disease.
Cataract
Hageman factor and kallikrein in pathogenesis of senile cataracts and the pseudoexfoliation syndrome.
Cerebral Infarction
Global cerebral infarction after aortic arch replacement surgery in a patient with postoperatively revealed factor XII deficiency: a case report.
Cerebrovascular Disorders
A study of hemostasis in ischemic cerebrovascular disease: IV. A five year follow-up of some blood coagulation parameters also including fibrinopeptide A, factor XII and prekallikrein.
Genotype distribution of the 46C/T polymorphism of coagulation factor XII in the Japanese population: absence of its association with ischemic cerebrovascular disease.
Hageman factor (factor XII) in cerebrovascular diseases.
Next-generation antithrombotics in ischemic stroke: preclinical perspective on 'bleeding-free antithrombosis'
Chediak-Higashi Syndrome
Oral Mucosa Bleeding Times of Normal Cats and Cats with Chediak-Higashi Syndrome or Hageman Trait (Factor XII Deficiency).
Cholecystitis, Acute
Induction of acute cholecystitis by activation of factor XII.
Chronic Urticaria
Interaction between C1-INA, coagulation, fibrinolysis and kinin system in hereditary angioneurotic edema (HANE) and urticaria.
Cluster Headache
A new headache syndrome? Headache resembling cluster headache (Horton's headache), with recurring bouts of homolateral retrobulbar neuritis, partial factor XII deficiency, bleeding tendency and a heterolateral convulsive episode.
So-called "vascular headache of the migraine type": one or more nosological entities?
coagulation factor ixa deficiency
Activation of factor VII during alimentary lipemia occurs in healthy adults and patients with congenital factor XII or factor XI deficiency, but not in patients with factor IX deficiency.
Fibrin formation, fibrinopeptide A release, and platelet thrombus dimensions on subendothelium exposed to flowing native blood: greater in factor XII and XI than in factor VIII and IX deficiency.
[Review of patients studied for coagulopathy in a Hematology/Oncology unit].
coagulation factor viia deficiency
Inherited bleeding disorders in Indian women with menorrhagia.
Resistance to activated protein C: evaluation of three functional assays.
coagulation factor xa deficiency
Inherited bleeding disorders in Indian women with menorrhagia.
[3 families with a congenital factor X deficiency, one of them with an associated factor XII deficiency]
coagulation factor xia deficiency
Activation of factor VII during alimentary lipemia occurs in healthy adults and patients with congenital factor XII or factor XI deficiency, but not in patients with factor IX deficiency.
Combined dys-form of homozygous factor XI deficiency and heterozygous factor XII deficiency.
Factor XI and factor XII as targets for new anticoagulants.
Factor XI Deficiency Alters the Cytokine Response and Activation of Contact Proteases during Polymicrobial Sepsis in Mice.
Factor XI deficiency enhances the pulmonary allergic response to house dust mite in mice independent of factor XII.
Factor XI deficiency in Kerry Blue Terriers.
Fibrin formation, fibrinopeptide A release, and platelet thrombus dimensions on subendothelium exposed to flowing native blood: greater in factor XII and XI than in factor VIII and IX deficiency.
Genetic analysis of a pedigree with combined factor XII and factor XI deficiency.
Normal platelet adhesiveness and aggregation in congenital PTA or Hageman factor deficiency.
Polyphosphate is a cofactor for the activation of factor XI by thrombin.
Preoperative screening for coagulopathy using prothrombin time and partial thromboplastin time in patients requiring primary cranial vault remodeling.
The enigma of severe factor XI deficiency without hemmorrhagic symptoms. Distinction from Hageman factor and "Fletcher factor" deficiency; family study; and problems of diagnosis.
[Review of patients studied for coagulopathy in a Hematology/Oncology unit].
coagulation factor xiia deficiency
A case of atypical hemolytic uremic syndrome due to anti-factor H antibody in a patient presenting with a factor XII deficiency identified two novel mutations.
A case of coagulation factor XII deficiency showed weak clot-formation.
A case of Hageman factor deficiency with myeloid leukaemia.
A combined deficiency of factor VIII and contact activation defect in a family of cats.
A comparison of the effects of factor XII deficiency and prekallikrein deficiency on thrombus formation.
A complete factor XII deficiency does not affect coagulopathy, inflammatory responses, and lethality, but attenuates early hypotension in endotoxemic mice.
A female hemophilia A combined with hereditary coagulation factor XII deficiency: a case report.
A frequent factor XII gene mutation in Hageman trait.
A new family with congenital factor XII deficiency.
A new headache syndrome? Headache resembling cluster headache (Horton's headache), with recurring bouts of homolateral retrobulbar neuritis, partial factor XII deficiency, bleeding tendency and a heterolateral convulsive episode.
A novel factor XII mutation, FXII R84P, causing factor XII deficiency in a patient with hereditary spastic paraplegia.
A novel homozygous missense mutation (Met527Ile) in a consanguineous marriage family with inherited factor XII deficiency.
A novel missense mutation in the factor XII gene in a litter of cats with factor XII deficiency.
A novel mutation in a patient with congenital coagulation factor XII deficiency.
Abnormal proteolytic degradation of von Willebrand factor after desmopressin infusion in a new subtype of von Willebrand disease (ID).
Acquired and congenital clotting syndromes.
Acquired factor XII deficiency following transanal excision of rectal lesion by transanal minimally invasive surgery (TAMIS): a case report and literature review.
Acquired factor XII Deficiency in a patient with nephrotic syndrome.
Acquired factor XII deficiency in a woman with recurrent pregnancy loss: working on a differential diagnosis in a single case.
Activated partial thromboplastin time and minor coagulopathies.
Activation of factor VII during alimentary lipemia occurs in healthy adults and patients with congenital factor XII or factor XI deficiency, but not in patients with factor IX deficiency.
Additional factor XII (Hageman factor) deficiency in hemophilia A and in von Willebrand syndrome.
Adult nephrotic syndrome and acquired coagulopathies: Hageman factor deficiency.
Anticoagulant therapy and pregnancy.
Aortic valve repair in a patient with factor XII deficiency.
Aortic valve replacement and ventricular septal defect repair in factor XII deficiency: An anesthetic challenge.
Aortic valve replacement in a patient with factor XII deficiency: case report.
Arterial and venous thrombosis and normal response to streptokinase treatment in a young patient with severe Hageman factor deficiency.
Autoantibodies and coagulation in reproductive medicine.
Behçet's syndrome and factor XII deficiency.
Biological and clinical heterogeneity of lupus and lupus-like anticoagulant in fifty-seven patients.
Blood coagulation dynamics under the conditions of Hageman factor deficiency: a mathematical model.
Captopril-induced changes on active and inactive renin in a patient with factor XII congenital deficiency.
Cardiopulmonary bypass and Factor XII deficiency.
Cardiopulmonary bypass in a child with severe Factor XII deficiency.
Cardiopulmonary bypass in a patient with factor XII deficiency.
Cardiopulmonary Bypass in a Patient with Factor XII Deficiency.
Cardiopulmonary bypass in patients with pre-existing coagulopathy.
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy with severe factor XII deficiency.
Cerebral visual impairment and intellectual disability caused by PGAP1 variants.
Characterization of factor XII Tenri, a rare CRM-negative factor XII deficiency.
Chronic thromboembolic pulmonary hypertension is a clot you cannot swat.
Clinical implications of factor XII deficiency.
Clinical relevance of isolated prolongation of the activated partial thromboplastin time in a cohort of adults undergoing surgical procedures.
Cluster headache-like headache, Hageman trait deficiency, retrobulbar neuritis, and giant aneurysm. Autonomic function studies.
Coagulation factor XII deficiency in the porpoise, Tursiops truncatus.
Coagulation factors IX through XIII and the risk of future venous thrombosis: the Longitudinal Investigation of Thromboembolism Etiology.
Coincidence of familial platelet glycoprotein Ib/IX deficiency (Bernard-Soulier syndrome), idiopathic autoantibody against platelet glycoprotein Ib/IX, familial appearance of antiphospholipid antibodies, and familial factor XII deficiency.
Combination of von Willebrand disease type 1 and partial factor XII deficiency in children: clinical evidence for a diminished bleeding tendency.
Combined dys-form of homozygous factor XI deficiency and heterozygous factor XII deficiency.
Combined severe factor XII deficiency and homozygous factor V Leiden mutation in a patient with venous thrombosis.
Combined von Willebrand disease and Hageman factor deficiency.
Combined von Willebrand factor deficiency and factor XII deficiency.
Combined von Willebrand's disease and factor XII deficiency in a carrier of haemophilia B.
Comparable levels of activity and antigen in factor XII deficiency: a study of 21 homozygotes and 58 heterozygotes.
Compound heterozygous mutations Glu502Lys and Met527Thr of the FXII gene in a patient with factor XII deficiency.
Concomitant ST-elevation myocardial infarction and deep vein thrombosis in a patient with severe factor XII deficiency: case report and review of the literature.
Congenital factor XII deficiency and cardiopulmonary bypass.
Congenital factor XII deficiency and lupus anticoagulant.
Congenital factor XII deficiency: successful open heart surgery and anticoagulation.
Contact factor deficiencies and cardiopulmonary bypass surgery: detection of the defect and monitoring of heparin.
Contact system dependent fibrinolytic activity in vivo: observations in healthy subjects and factor XII deficient patients.
Deep venous thrombosis and previous myocardial infarction in mild factor XII deficiency: a risk factor for both venous and arterial thrombosis.
Diminished adhesiveness of platelets to collagen in a patient with factor XII deficiency.
Donor-to-recipient transmission of factor XII deficiency by orthotopic liver transplantation.
Double Heterozygous Mutations (Cys247Tyr and 252delAsn) Cause Factor XII Deficiency in a Chinese Family.
Effect of factor XII deficiency on pregnancy and parturition.
Endovenous Thermal Ablation for a Varicose Vein Patient with Factor XII Deficiency: A Case Report.
Essential thrombocytosis accompanied by coagulation factor XII deficiency: a case report.
Evaluation of the clotting defect in a factor XII-deficient kindred.
Evidence against collagen activation of platelet-associated factor XI as a mechanism for initiating intrinsic clotting.
Factor XI activation in a revised model of blood coagulation.
Factor XI and factor XII as targets for new anticoagulants.
Factor XI contributes to thrombin generation in the absence of factor XII.
Factor XII (Hageman Factor) Deficiency: a rare harbinger of life threatening complications.
Factor XII and partial prekallikrein deficiencies in a dog with recurrent gastrointestinal hemorrhage.
Factor XII deficiency acquired by orthotopic liver transplantation: case report and review of the literature.
Factor XII deficiency and cardiopulmonary bypass.
Factor XII Deficiency and Cardiopulmonary Bypass.
Factor XII deficiency and cardiopulmonary bypass: use of a novel modification of the activated clotting time to monitor anticoagulation.
Factor XII deficiency and central retinal vein occlusion.
Factor XII deficiency and pregnancy.
Factor XII deficiency and recurrent sixth nerve palsy.
Factor XII deficiency and von Willebrand's disease in a family of miniature poodle dogs.
Factor XII deficiency associated with coronary stent thrombosis.
Factor XII deficiency associated with loin pain/haematuria syndrome.
Factor XII deficiency in a man with gout and angioimmunoblastic lymphadenopathy.
Factor XII deficiency in asymptomatic Saudi population: A retrospective cohort study.
Factor XII deficiency in women with recurrent miscarriage.
Factor XII deficiency is common in domestic cats and associated with two high frequency F12 mutations.
Factor XII deficiency is strongly associated with primary recurrent abortions.
Factor XII Deficiency Mimicking Bleeding Diathesis: A Unique Presentation and Diagnostic Pitfall.
Factor XII deficiency with systemic lupus erythematosus. Biological implications.
Factor XII deficiency: a possible cause of livedo with ulceration?
Factor XII deficiency: a thrombophilic risk factor for retinal vein occlusion.
Factor XII gene alteration in Hageman trait detected by TaqI restriction enzyme.
Factor XII Ofunato: Lys346Asn mutation associated with blood coagulation factor XII deficiency causes impaired secretion through a proteasome-mediated degradation.
Factor XII Shizuoka, a novel mutation (Ala392Thr) identified and characterized in a patient with congenital coagulation factor XII deficiency.
Factor XII Tenri, a novel cross-reacting material negative factor XII deficiency, occurs through a proteasome-mediated degradation.
Factor XII-Deficient Chicken Plasma as a Useful Target for Screening of Pro- and Anticoagulant Animal Venom Toxins.
Feline factor XII (Hageman) deficiency.
Fibrin formation, fibrinopeptide A release, and platelet thrombus dimensions on subendothelium exposed to flowing native blood: greater in factor XII and XI than in factor VIII and IX deficiency.
Fibrinolytic defects and recurrent miscarriage: a systematic review and meta-analysis.
Fibrinolytic studies in 13 unrelated families with factor XII deficiency.
Genetic analyses and expression studies identified a novel mutation (W486C) as a molecular basis of congenital coagulation factor XII deficiency.
Genetic analysis of a hereditary factor XII deficiency pedigree of a consanguineous marriage due to a homozygous F12 gene mutation: Gly341Arg.
Genetic analysis of a novel missense mutation (Gly542Ser) with factor XII deficiency in a Chinese patient of consanguineous marriage.
Genetic analysis of a pedigree with hereditary coagulation factor XII deficiency.
Genetic study in patients with factor XII deficiency: a report of three new mutations exon 13 (Q501STOP), exon 14 (P547L) and -13C>T promoter region in three compound heterozygotes.
Global cerebral infarction after aortic arch replacement surgery in a patient with postoperatively revealed factor XII deficiency: a case report.
Hageman factor deficiency (Hageman trait). Case report and review of the literature.
Hageman factor deficiency and oral contraceptives.
HAGEMAN FACTOR DEFICIENCY IN A CHILD.
Hageman factor deficiency in ataxia telangiectasia.
Hageman factor deficiency presentation and implications for management.
Hageman factor deficiency. Report of a case found in a Japanese girl.
Hemophilia D factor (factor XII), red-cell deformability and platelet aggregates in raptors.
Hemostyptic effect of oxidized cellulose on blood platelets.
High incidence of plasma factor XII deficiency in normal Korean subjects.
Homozygous type I plasminogen deficiency.
Huge left atrial thrombus with mitral stenosis in congenital factor XII deficiency.
Human factor XII binding to the glycoprotein Ib-IX-V complex inhibits thrombin-induced platelet aggregation.
Human homozygous type I plasminogen deficiency and ligneous conjunctivitis.
Identification and characterization of two novel mutations (Q421 K and R123P) in congenital factor XII deficiency.
Identifying hypocoagulable states with a modified global assay of overall haemostasis potential in plasma.
Immunoreactive tissue kallikrein in human serum.
Implications for cardiac surgery in patients with factor XII deficiency.
Incidental Detection of Factor XII Deficiency Following Coronary Artery Bypass Grafting.
Influence of factor XII deficiency on activated partial thromboplastin time (aPTT) in critically ill patients.
Inherited bleeding disorders in Indian women with menorrhagia.
Inherited bleeding disorders.
Invited Commentary. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy with severe factor XII deficiency.
Is factor XII deficiency related to recurrent miscarriage?
John Hageman's factor and deep-vein thrombosis: Leiden thrombophilia Study.
Kallikrein and prekallikrein levels in a large number of congenital clotting deficiencies and abnormalities.
Ketanserin in women with chronic hypertension and underlying thrombophilia.
Lemierre's syndrome complicating bacterial pharyngitis in a patient with undiagnosed factor XII deficiency.
Loss of the largest von Willebrand factor multimers from the plasma of patients with congenital cardiac defects.
Low factor XII level in an individual with Sotos syndrome.
Major abdominal surgery on a patient with factor XII deficiency and lupus anticoagulant: no postoperative DVT as judged by the fibrinogen uptake test.
Management of cardiopulmonary bypass in a patient with congenital factor XII deficiency.
Mitral valve repair and cardiac transplantation in a patient with factor XII deficiency.
MODERATE FACTOR XII DEFICIENCY.
Molecular analysis of factor XII gene in Thai patients with factor XII deficiency.
Molecular Characterization of a Novel Missense Mutation (Asp538Asn) in a Chinese Patient with Factor XII Deficiency.
Molecular Characterization of Cat Factor XII Gene and Identification of a Mutation Causing Factor XII Deficiency in a Domestic Shorthair Cat Colony.
Molecular characterization of coagulation factor XII deficiency in a Japanese family.
Molecular genetic analysis of Korean patients with coagulation factor XII deficiency.
Myocardial infarction with normal coronary arteries and factor XII deficiency.
New agents for thromboprotection. A role for factor XII and XIIa inhibition.
New families with factor XII deficiency.
Normal platelet adhesiveness and aggregation in congenital PTA or Hageman factor deficiency.
Novel deleterious mutation in the F12 gene in a Korean family with severe coagulation factor XII deficiency.
Novel mutations in congenital factor XII deficiency.
Occurrence of coagulation factor deficiency in post-tonsillectomy hemorrhage.
Oral Mucosa Bleeding Times of Normal Cats and Cats with Chediak-Higashi Syndrome or Hageman Trait (Factor XII Deficiency).
Orbital subperiosteal hemorrhage in a patient with factor VIII and factor XII Deficiency.
Pathogenetic potential of antiphospholipid antibodies.
Periodic painful purpura: Fact or factitious?
Perioperative management of a patient with severe factor XII deficiency.
Perioperative management of cardiac surgery patients with factor XII deficiency - two case reports.
Perioperative use of the Thrombelastograph in patients with inherited bleeding disorders.
Phosphatidylethanolamine participates in the stimulation of the contact system of coagulation by very-low-density lipoproteins.
Plasma prekallikrein: quantitative determination by direct activation with Hageman factor fragment (beta-XIIa).
Platelet polyphosphates: The nexus of primary and secondary hemostasis.
Polyphosphate is a cofactor for the activation of factor XI by thrombin.
Preoperative bleeding risk assessment with ISTH-BAT and laboratory tests in patients undergoing elective surgery: A prospective cohort study.
Prevalence of factor XII (Hageman factor) deficiency among 426 patients with coronary heart disease awaiting cardiac surgery.
Prevalent factor XII deficiency in cancer patients with isolated aPTT prolongation.
Prolonged activated partial thromboplastin time secondary to factor XII deficiency in two surgical patients.
Pseudo factor XII deficiency and phospholipid antibodies.
Pseudopathologies of hemostasis and dental surgery.
Reaction of blood with artificial surfaces of hemodialyzers. Studies of human blood with platelet defects or coagulation factor deficiencies.
Recurrent reproductive wastage and immunologic factors.
Recurrent subarachnoid haemorrhages in patient with Hageman factor deficiency.
Recurrent thrombosis in a patient with factor XII deficiency.
Reduction of contact activation related fibrinolytic activity in factor XII deficient patients. Further evidence for the role of the contact system in fibrinolysis in vivo.
Relationship between Factor XII deficiency and thrombosis: the debate is still open?
Report 2 cases of congenital factor XII deficiency: a rare coagulation disorder.
Resistance to activated protein C: evaluation of three functional assays.
Respective evaluation of the prevalence of haemostasis abnormalities in unexplained primary early recurrent miscarriages. The Nimes Obstetricians and Haematologists (NOHA) Study.
Response of factor XII to DDAVP in patients with Hageman factor deficiency.
Retinal vein occlusion in child with rare mutations in genes for thrombophilia.
Retinal venous thrombosis in a young patient with coagulation factor xii deficiency.
Risk Factors and Outcomes of Recurrent Pregnancy Loss in Japan.
Role of factor XII in thrombin generation and fibrinolysis during cardiopulmonary bypass.
Rosai-Dorfman disease with factor XII deficiency.
Severe Fletcher factor (plasma prekallikrein) deficiency with partial deficiency of Hageman factor (factor XII): report of a case with observation on in vivo and in vitro leukocyte chemotaxis.
So-called "vascular headache of the migraine type": one or more nosological entities?
Subdural haematoma and factor XII deficiency in a Chinese infant.
Subdural hematoma in a patient with Hageman trait--case report.
Superficial migratory thrombophlebitis and factor XII deficiency.
Surgical management in the patient with congenital factor XII deficiency. Report of a case.
Symptomatic combined homozygous factor XII deficiency and heterozygous factor V Leiden. luscaber@tin.it.
The discrimination of factor XII deficiency and lupus anticoagulant.
The Hageman factor: determinations of its concentration during the neonatal period and presentation of a case of Hageman factor deficiency.
The inheritance pattern of factor XII (Hageman) deficiency in domestic cats.
The old and the new in prekallikrein deficiency: historical context and a family from Argentina with PK deficiency due to a new mutation (Arg541Gln) in exon 14 associated with a common polymorphysm (Asn124Ser) in exon 5.
The possible role of platelets in bypassing the contact phase of blood coagulation.
The prevalence of factor XII deficiency in 103 orally anticoagulated outpatients suffering from recurrent venous and/or arterial thromboembolism.
The Standard Point-of-Care Hemochron Jr. ACT+ Test in Monitoring Heparin Administration for Cardiopulmonary Bypass in Severe Factor XII Deficiency.
Thromboembolism in Hageman trait.
Thrombophilia with a combination of antithrombin III and factor XII deficiency.
Thrombosis in patients with heterozygous and homozygous factor XII deficiency is not explained by the associated presence of factor V Leiden.
Thrombosis in subjects with homozygous and heterozygous factor XII deficiency.
Thrombosis-free surgical procedures in severe (Homozygote) factor XII deficiency: report of four additional cases and literature review.
Thrombus formation on transcatheter ASD occluder device in a patient with coagulation factor XII deficiency.
Transient acquired Factor XII deficiency associated with moderately severe Covid-19 pneumonia.
Transient lupus anticoagulant associated with hypoprothrombinemia and factor XII deficiency following adenovirus infection.
Treatment of hereditary and acquired thrombophilic disorders.
Troubleshooting an isolate prolongation of activated partial thromboplastin time in a patient with acute myocardial infarction-a paradigmatic case report.
Two different incubation times for the activated partial thromboplastin time (APTT): a new criterion for diagnosis of lupus anticoagulant.
Two Novel Mutations (G774A and A1685G) Causing Coagulation Factor XII Deficiency in a Patient with Acute Inferior Myocardial Infarction.
Value of preoperative prothrombin time/partial thromboplastin time as a predictor of postoperative hemorrhage in pediatric patients undergoing tonsillectomy.
Variations of factor XII level during pregnancy in a woman with Hageman factor deficiency.
Varicella and thrombotic complications associated with transient protein C and protein S deficiencies in children.
[3 families with a congenital factor X deficiency, one of them with an associated factor XII deficiency]
[A case of Hageman factor deficiency (factor XII deficiency).]
[A patient with isolated prolongation of aPTT without hemorrhagic diathesis anamnesis: severe, hereditary factor XII deficiency]
[Acute lung injury as a consequence of fresh frozen plasma administration in a patient with factor XII deficiency.]
[Analysis of a consanguineous pedigree affected with hereditary coagulation factor XII deficiency caused by homozygous Gly341Arg mutation].
[Analysis of a pedigree affected with hereditary coagulation factor XII deficiency due to a homozygous 252delAsn deletion of F12 gene].
[Analysis of an abnormal coagulation profile in children qualified for adenoidectomy/tonsilectomy]
[Analysis of an hereditary coagulation factor XII deficiency in a consanguineous pedigree].
[Anesthetic management of a patient with blood coagulation factor XII deficiency]
[Antiphospholipid antibodies in asymptomatic pediatric patients]
[Case of factor XII deficiency with prolonged bleeding time]
[Coagulation factor XII deficiency, a contribution to thrombophilia]
[Congenital deficiency of factor Xii and spontaenous venous thrombosis treated with urokinase]
[Congenital factor XII deficiency: a rare cause of increased activated cephalin time]
[Deep venous thrombosis of the arm revealing a congenital Factor XII deficiency]
[Disorders in the contact phase system of blood coagulation as a cause of increased partial thromboplastin time]
[Effect of oxidized cellulose on fibrin formation and blood platelets]
[Electroimmunoassay of factor XII antigen increased sensitivity by silver staining of immunoprecipitate--factor XII antigen in cases from 9 Japanese families with congenital factor XII deficiency]
[Factor XII (Hageman factor) deficiency: a risk factor for development of thromboembolism. Incidence of factor XII deficiency in patients after recurrent venous or arterial thromboembolism and myocardial infarction]
[Factor XII (HAGEMAN FACTOR)]
[Factor XII deficiency - Hageman trait. Additional diagnostic procedures]
[Factor XII deficiency - Hageman trait. Report of 2 cases]
[Factor XII deficiency and/or anticoagulant treatment at the site of an intracerebral hematoma]
[Factor XII deficiency in two brothers]
[Factor XII deficiency]
[Familial study in congenital Hageman factor deficiency (blood coagulation factor XII)]
[Hageman factor deficiency (factor XII)--hemorrhage or thrombosis?]
[Hageman factor deficiency. Apropos of a case]
[Hageman factor deficiency.]
[HAGEMAN FACTOR DEFICIENCY.]
[Hageman factor deficiency: second case found in Japanese]
[Hemopericardium in hypodermosis in a child with partial factor IX and factor XII deficiencies]
[Hemorrhage after tonsillectomy in a patient with PTA and Hageman factor deficiency: clinico-therapeutic considerations]
[Hemorrhagic diathesis associated with partial factor XII deficiency]
[Importance of Quick, partial thromboplastin time, and Co].
[Is factor XII deficiency a contraindication to surgery?]
[Ischemic stroke in a patient with factor XII (Hageman) deficiency]
[Isolated prolongation of the PTT: 2-year retrospective study]
[Marginal hemophilia: Hageman factor deficiency.]
[Moderate deficiency of Factor XII associated with postoperative deep venous thrombosis]
[Prothrombin fragment 1+2 (F1+2), thrombin-antithrombin III complex(TAT) and thrombophilia parameters in orally anticoagulated patients with inferior vena cava filters]
[Recurrent venous thromboses in hypoplasia of the vena cava inferior and factor XII deficiency]
[Review of patients studied for coagulopathy in a Hematology/Oncology unit].
[Sacroiliitis in familial Mediterranean fever]
[Study of a family with factor XII deficiency]
[Successes and failures of the activated partial thromboplastin time in the preoperative evaluation]
[The genetics of factor XII deficiency]
[Thrombophlebitis and pulmonary embolism in congenital factor XII deficiency]
[Tonsillectomy in factor XII deficiency]
[Unsuspected prolonged activated partial thromboplastin time in emergency surgery. Diagnostic and therapeutic guide]
[Use of chromogenic substrates in the clarification of disorders in the early stages of blood coagulation]
Colitis
The Coagulation Factors Fibrinogen, Thrombin, and Factor XII in Inflammatory Disorders-A Systematic Review.
Coma
Prekallikrein, HMW-kininogen and factor XII in various disease states.
Communicable Diseases
Severe lung lesions caused by Salmonella are prevented by inhibition of the contact system.
Coronary Artery Disease
Activated factor XII levels and factor XII 46C>T genotype in relation to coronary artery calcification in patients with type 1 diabetes and healthy subjects.
Acute coronary syndromes do not promote prolonged in vivo FXII-dependent prothrombotic activity.
Factor XII 46C --> T gene polymorphism in Chilean subjects with coronary artery disease and controls.
FXII (46C-->T) polymorphism and in vivo generation of FXII activity--gene frequencies and relationship in patients with coronary artery disease.
Levels of activated FXII in survivors of myocardial infarction--association with circulating risk factors and extent of coronary artery disease.
Participation of Hageman factor dependent pathways in human disease states.
Rapid factor XII (46C-->T) genotyping by fluorescence resonance energy transfer in patients with coronary artery disease or thrombophilia.
Coronary Disease
Activated factor XII in rheumatoid arthritis.
Acute coronary syndromes do not promote prolonged in vivo FXII-dependent prothrombotic activity.
Association of the factor XII 46C>T polymorphism with risk of coronary heart disease (CHD) in the WOSCOPS study.
Coagulation factor XII (FXII) activity, activated FXII, distribution of FXII C46T gene polymorphism and coronary risk.
Epidemiological and genetic associations of activated factor XII concentration with factor VII activity, fibrinopeptide A concentration, and risk of coronary heart disease in men.
Expression, refolding, and activation of the catalytic domain of human blood coagulation factor XII.
Prevalence of factor XII (Hageman factor) deficiency among 426 patients with coronary heart disease awaiting cardiac surgery.
Risk of coronary heart disease and activation of factor XII in middle-aged men.
Coronary Stenosis
Levels of activated FXII in survivors of myocardial infarction--association with circulating risk factors and extent of coronary artery disease.
Coronary Thrombosis
Inhibition of Platelet Adhesion from Surface Modified Polyurethane Membranes.
COVID-19
A comprehensive insight into the role of zinc deficiency in the renin-angiotensin and kinin-kallikrein system dysfunctions in COVID-19 patients.
Age-dependent possible role of contact-activated blood coagulation factor XII as a potential contributor to the “bradykinin storm” in COVID-19 patients
Defective NET clearance contributes to sustained FXII activation in COVID-19-associated pulmonary thrombo-inflammation.
Platelets Promote Thromboinflammation in SARS-CoV-2 Pneumonia.
Recent updates in the clinical trials of therapeutic monoclonal antibodies targeting cytokine storm for the management of COVID-19.
Thromboplasminflammation in COVID-19 Coagulopathy: Three Viewpoints for Diagnostic and Therapeutic Strategies.
Transient acquired Factor XII deficiency associated with moderately severe Covid-19 pneumonia.
Craniocerebral Trauma
Orbital subperiosteal hemorrhage in a patient with factor VIII and factor XII Deficiency.
Cryoglobulinemia
Effects of cryoglobulin on fibrin clot formation and fibrinolysis.
Crystal Arthropathies
Urate crystal arthritis in animals lacking Hageman factor.
Cushing Syndrome
Hageman Factor C46T Promoter Gene Polymorphism in Patients with Hypercortisolism.
Cystic Fibrosis
Adult cystic fibrosis patients with and without infective exacerbations and their factor XII levels.
Normal plasma arginine esterase and the Hageman factor (factor XII) -prekallikrein-kininogen system in cystic fibrosis.
Participation of Hageman factor dependent pathways in human disease states.
Dementia
Plasma contact factors as novel biomarkers for diagnosing Alzheimer's disease.
Dengue
Evaluation of the plasma kinin system in dengue hemorrhagic fever.
Diabetes Mellitus
Contact phase of coagulation in diabetes mellitus after aspirin administration.
[Activated factor XII in patients with hyperglycaemia and dyslipidaemia]
Diabetes Mellitus, Type 1
Activated factor XII levels and factor XII 46C>T genotype in relation to coronary artery calcification in patients with type 1 diabetes and healthy subjects.
Diabetes, Gestational
Comparison of factor XII levels in gestational diabetes, fetal macrosomia, and healthy pregnancies.
Diabetic Retinopathy
Activation of Factor XII and Kallikrein-kinin System Combined with Neutrophil Extracellular Trap Formation in Diabetic Retinopathy.
Coagulation factors of contact phase of haemostasis are normal in well-controlled type-I diabetic patients despite presence of diabetic retinopathy.
High Subretinal Fluid Procoagulant Activity in Rhegmatogenous Retinal Detachment.
Plasma kallikrein and diabetic macular edema.
The kallikrein-kinin system in diabetic retinopathy: lessons for the kidney.
Disseminated Intravascular Coagulation
A biochemical study on the kinetics of kininogen in asphyxiated newborn.
Hageman factor activity in liquoid-induced consumption coagulopathy. Failure to prevent the drop in Hageman factor activity by anticoagulation with a coumarin derivative.
Hageman factor and disseminated intravascular coagulation (DIC) in newborns and rabbits.
Inhibition of factor XI activation attenuates inflammation and coagulopathy while improving the survival of mouse polymicrobial sepsis.
Plasma prekallikrein, factor XII, antithrombin III, C1(-)-inhibitor and alpha 2-macroglobulin in critically ill patients with suspected disseminated intravascular coagulation (DIC).
Prevention by aspirin of the classic generalized Shwartzman reaction.
Prevention by glucocorticoids of disseminated intravascular coagulation induced by endotoxin: mechanisms.
The role of Hageman factor in disseminated intravascular coagulation induced by septicemia, neoplasia, or liver disease.
Thromboplasminflammation in COVID-19 Coagulopathy: Three Viewpoints for Diagnostic and Therapeutic Strategies.
Dwarfism, Pituitary
[A case of pituitary dwarfism with hyperlipemia, factor XII and XI deficiency, and low level of NK activity]
Ehlers-Danlos Syndrome
Repair of cardiac defect in patient with Ehlers-Danlos syndrome and deficiency of Hageman factor.
Endometrial Hyperplasia
Angioedema attacks related to endometrial hyperplasia in a case of estrogen-dependent factor XII hereditary angioedema.
Epiretinal Membrane
High Subretinal Fluid Procoagulant Activity in Rhegmatogenous Retinal Detachment.
Exfoliation Syndrome
Hageman factor and kallikrein in pathogenesis of senile cataracts and the pseudoexfoliation syndrome.
Factor VII Deficiency
Inherited bleeding disorders in Indian women with menorrhagia.
Resistance to activated protein C: evaluation of three functional assays.
Factor X Deficiency
Inherited bleeding disorders in Indian women with menorrhagia.
[3 families with a congenital factor X deficiency, one of them with an associated factor XII deficiency]
Factor XI Deficiency
Activation of factor VII during alimentary lipemia occurs in healthy adults and patients with congenital factor XII or factor XI deficiency, but not in patients with factor IX deficiency.
Combined dys-form of homozygous factor XI deficiency and heterozygous factor XII deficiency.
Factor XI and factor XII as targets for new anticoagulants.
Factor XI Deficiency Alters the Cytokine Response and Activation of Contact Proteases during Polymicrobial Sepsis in Mice.
Factor XI deficiency enhances the pulmonary allergic response to house dust mite in mice independent of factor XII.
Factor XI deficiency in Kerry Blue Terriers.
Fibrin formation, fibrinopeptide A release, and platelet thrombus dimensions on subendothelium exposed to flowing native blood: greater in factor XII and XI than in factor VIII and IX deficiency.
Genetic analysis of a pedigree with combined factor XII and factor XI deficiency.
Normal platelet adhesiveness and aggregation in congenital PTA or Hageman factor deficiency.
Polyphosphate is a cofactor for the activation of factor XI by thrombin.
Preoperative screening for coagulopathy using prothrombin time and partial thromboplastin time in patients requiring primary cranial vault remodeling.
The enigma of severe factor XI deficiency without hemmorrhagic symptoms. Distinction from Hageman factor and "Fletcher factor" deficiency; family study; and problems of diagnosis.
[Review of patients studied for coagulopathy in a Hematology/Oncology unit].
Factor XII Deficiency
A case of atypical hemolytic uremic syndrome due to anti-factor H antibody in a patient presenting with a factor XII deficiency identified two novel mutations.
A case of coagulation factor XII deficiency showed weak clot-formation.
A case of Hageman factor deficiency with myeloid leukaemia.
A combined deficiency of factor VIII and contact activation defect in a family of cats.
A comparison of the effects of factor XII deficiency and prekallikrein deficiency on thrombus formation.
A complete factor XII deficiency does not affect coagulopathy, inflammatory responses, and lethality, but attenuates early hypotension in endotoxemic mice.
A female hemophilia A combined with hereditary coagulation factor XII deficiency: a case report.
A frequent factor XII gene mutation in Hageman trait.
A new family with congenital factor XII deficiency.
A new headache syndrome? Headache resembling cluster headache (Horton's headache), with recurring bouts of homolateral retrobulbar neuritis, partial factor XII deficiency, bleeding tendency and a heterolateral convulsive episode.
A novel factor XII mutation, FXII R84P, causing factor XII deficiency in a patient with hereditary spastic paraplegia.
A novel homozygous missense mutation (Met527Ile) in a consanguineous marriage family with inherited factor XII deficiency.
A novel missense mutation in the factor XII gene in a litter of cats with factor XII deficiency.
A novel mutation in a patient with congenital coagulation factor XII deficiency.
Abnormal proteolytic degradation of von Willebrand factor after desmopressin infusion in a new subtype of von Willebrand disease (ID).
Acquired and congenital clotting syndromes.
Acquired factor XII deficiency following transanal excision of rectal lesion by transanal minimally invasive surgery (TAMIS): a case report and literature review.
Acquired factor XII Deficiency in a patient with nephrotic syndrome.
Acquired factor XII deficiency in a woman with recurrent pregnancy loss: working on a differential diagnosis in a single case.
Activated partial thromboplastin time and minor coagulopathies.
Activation of factor VII during alimentary lipemia occurs in healthy adults and patients with congenital factor XII or factor XI deficiency, but not in patients with factor IX deficiency.
Additional factor XII (Hageman factor) deficiency in hemophilia A and in von Willebrand syndrome.
Adult nephrotic syndrome and acquired coagulopathies: Hageman factor deficiency.
Anticoagulant therapy and pregnancy.
Aortic valve repair in a patient with factor XII deficiency.
Aortic valve replacement and ventricular septal defect repair in factor XII deficiency: An anesthetic challenge.
Aortic valve replacement in a patient with factor XII deficiency: case report.
Arterial and venous thrombosis and normal response to streptokinase treatment in a young patient with severe Hageman factor deficiency.
Autoantibodies and coagulation in reproductive medicine.
Behçet's syndrome and factor XII deficiency.
Biological and clinical heterogeneity of lupus and lupus-like anticoagulant in fifty-seven patients.
Blood coagulation dynamics under the conditions of Hageman factor deficiency: a mathematical model.
Captopril-induced changes on active and inactive renin in a patient with factor XII congenital deficiency.
Cardiopulmonary bypass and Factor XII deficiency.
Cardiopulmonary bypass in a child with severe Factor XII deficiency.
Cardiopulmonary bypass in a patient with factor XII deficiency.
Cardiopulmonary Bypass in a Patient with Factor XII Deficiency.
Cardiopulmonary bypass in patients with pre-existing coagulopathy.
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy with severe factor XII deficiency.
Cerebral visual impairment and intellectual disability caused by PGAP1 variants.
Characterization of factor XII Tenri, a rare CRM-negative factor XII deficiency.
Chronic thromboembolic pulmonary hypertension is a clot you cannot swat.
Classic gout in Hageman factor (Factor XII) deficiency.
Clinical implications of factor XII deficiency.
Clinical relevance of isolated prolongation of the activated partial thromboplastin time in a cohort of adults undergoing surgical procedures.
Cluster headache-like headache, Hageman trait deficiency, retrobulbar neuritis, and giant aneurysm. Autonomic function studies.
Coagulation factor XII deficiency in the porpoise, Tursiops truncatus.
Coagulation factors IX through XIII and the risk of future venous thrombosis: the Longitudinal Investigation of Thromboembolism Etiology.
Coincidence of familial platelet glycoprotein Ib/IX deficiency (Bernard-Soulier syndrome), idiopathic autoantibody against platelet glycoprotein Ib/IX, familial appearance of antiphospholipid antibodies, and familial factor XII deficiency.
Combination of von Willebrand disease type 1 and partial factor XII deficiency in children: clinical evidence for a diminished bleeding tendency.
Combined dys-form of homozygous factor XI deficiency and heterozygous factor XII deficiency.
Combined severe factor XII deficiency and homozygous factor V Leiden mutation in a patient with venous thrombosis.
Combined von Willebrand disease and Hageman factor deficiency.
Combined von Willebrand factor deficiency and factor XII deficiency.
Combined von Willebrand's disease and factor XII deficiency in a carrier of haemophilia B.
Comparable levels of activity and antigen in factor XII deficiency: a study of 21 homozygotes and 58 heterozygotes.
Compound heterozygous mutations Glu502Lys and Met527Thr of the FXII gene in a patient with factor XII deficiency.
Concomitant ST-elevation myocardial infarction and deep vein thrombosis in a patient with severe factor XII deficiency: case report and review of the literature.
Congenital factor XII deficiency and cardiopulmonary bypass.
Congenital factor XII deficiency and lupus anticoagulant.
Congenital factor XII deficiency: successful open heart surgery and anticoagulation.
Contact factor deficiencies and cardiopulmonary bypass surgery: detection of the defect and monitoring of heparin.
Contact system dependent fibrinolytic activity in vivo: observations in healthy subjects and factor XII deficient patients.
Deep venous thrombosis and previous myocardial infarction in mild factor XII deficiency: a risk factor for both venous and arterial thrombosis.
Diminished adhesiveness of platelets to collagen in a patient with factor XII deficiency.
Donor-to-recipient transmission of factor XII deficiency by orthotopic liver transplantation.
Double Heterozygous Mutations (Cys247Tyr and 252delAsn) Cause Factor XII Deficiency in a Chinese Family.
Effect of factor XII deficiency on pregnancy and parturition.
Endovenous Thermal Ablation for a Varicose Vein Patient with Factor XII Deficiency: A Case Report.
Essential thrombocytosis accompanied by coagulation factor XII deficiency: a case report.
Evaluation of the clotting defect in a factor XII-deficient kindred.
Evidence against collagen activation of platelet-associated factor XI as a mechanism for initiating intrinsic clotting.
Factor XI activation in a revised model of blood coagulation.
Factor XI and factor XII as targets for new anticoagulants.
Factor XI contributes to thrombin generation in the absence of factor XII.
Factor XII (Hageman Factor) Deficiency: a rare harbinger of life threatening complications.
Factor XII and partial prekallikrein deficiencies in a dog with recurrent gastrointestinal hemorrhage.
Factor XII deficiency acquired by orthotopic liver transplantation: case report and review of the literature.
Factor XII deficiency and cardiopulmonary bypass.
Factor XII Deficiency and Cardiopulmonary Bypass.
Factor XII deficiency and cardiopulmonary bypass: use of a novel modification of the activated clotting time to monitor anticoagulation.
Factor XII deficiency and central retinal vein occlusion.
Factor XII deficiency and pregnancy.
Factor XII deficiency and recurrent sixth nerve palsy.
Factor XII deficiency and von Willebrand's disease in a family of miniature poodle dogs.
Factor XII deficiency associated with coronary stent thrombosis.
Factor XII deficiency associated with loin pain/haematuria syndrome.
Factor XII deficiency in a man with gout and angioimmunoblastic lymphadenopathy.
Factor XII deficiency in asymptomatic Saudi population: A retrospective cohort study.
Factor XII deficiency in women with recurrent miscarriage.
Factor XII deficiency is common in domestic cats and associated with two high frequency F12 mutations.
Factor XII deficiency is strongly associated with primary recurrent abortions.
Factor XII Deficiency Mimicking Bleeding Diathesis: A Unique Presentation and Diagnostic Pitfall.
Factor XII deficiency with systemic lupus erythematosus. Biological implications.
Factor XII deficiency: a possible cause of livedo with ulceration?
Factor XII deficiency: a thrombophilic risk factor for retinal vein occlusion.
Factor XII gene alteration in Hageman trait detected by TaqI restriction enzyme.
Factor XII Ofunato: Lys346Asn mutation associated with blood coagulation factor XII deficiency causes impaired secretion through a proteasome-mediated degradation.
Factor XII Shizuoka, a novel mutation (Ala392Thr) identified and characterized in a patient with congenital coagulation factor XII deficiency.
Factor XII Tenri, a novel cross-reacting material negative factor XII deficiency, occurs through a proteasome-mediated degradation.
Factor XII-Deficient Chicken Plasma as a Useful Target for Screening of Pro- and Anticoagulant Animal Venom Toxins.
Feline factor XII (Hageman) deficiency.
Fibrin formation, fibrinopeptide A release, and platelet thrombus dimensions on subendothelium exposed to flowing native blood: greater in factor XII and XI than in factor VIII and IX deficiency.
Fibrinolytic defects and recurrent miscarriage: a systematic review and meta-analysis.
Fibrinolytic studies in 13 unrelated families with factor XII deficiency.
Genetic analyses and expression studies identified a novel mutation (W486C) as a molecular basis of congenital coagulation factor XII deficiency.
Genetic analysis of a hereditary factor XII deficiency pedigree of a consanguineous marriage due to a homozygous F12 gene mutation: Gly341Arg.
Genetic analysis of a novel missense mutation (Gly542Ser) with factor XII deficiency in a Chinese patient of consanguineous marriage.
Genetic analysis of a pedigree with hereditary coagulation factor XII deficiency.
Genetic study in patients with factor XII deficiency: a report of three new mutations exon 13 (Q501STOP), exon 14 (P547L) and -13C>T promoter region in three compound heterozygotes.
Global cerebral infarction after aortic arch replacement surgery in a patient with postoperatively revealed factor XII deficiency: a case report.
Hageman factor deficiency (Hageman trait). Case report and review of the literature.
Hageman factor deficiency and oral contraceptives.
HAGEMAN FACTOR DEFICIENCY IN A CHILD.
Hageman factor deficiency in ataxia telangiectasia.
Hageman factor deficiency presentation and implications for management.
Hageman factor deficiency. Report of a case found in a Japanese girl.
Hemophilia D factor (factor XII), red-cell deformability and platelet aggregates in raptors.
Hemostyptic effect of oxidized cellulose on blood platelets.
High incidence of plasma factor XII deficiency in normal Korean subjects.
Homozygous type I plasminogen deficiency.
Huge left atrial thrombus with mitral stenosis in congenital factor XII deficiency.
Human factor XII binding to the glycoprotein Ib-IX-V complex inhibits thrombin-induced platelet aggregation.
Human homozygous type I plasminogen deficiency and ligneous conjunctivitis.
Identification and characterization of two novel mutations (Q421 K and R123P) in congenital factor XII deficiency.
Identifying hypocoagulable states with a modified global assay of overall haemostasis potential in plasma.
Immunoreactive tissue kallikrein in human serum.
Implications for cardiac surgery in patients with factor XII deficiency.
Incidental Detection of Factor XII Deficiency Following Coronary Artery Bypass Grafting.
Influence of factor XII deficiency on activated partial thromboplastin time (aPTT) in critically ill patients.
Inherited bleeding disorders in Indian women with menorrhagia.
Inherited bleeding disorders.
Intrinsic plasma fibrinolysis: involvement of urokinase-related activity in the factor XII-independent plasminogen proactivator pathway.
Invited Commentary. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy with severe factor XII deficiency.
Is factor XII deficiency related to recurrent miscarriage?
Isolation and properties of an abnormal Hageman factor (Factor XII) molecule in a cross-reacting material-positive hageman trait plasma.
John Hageman's factor and deep-vein thrombosis: Leiden thrombophilia Study.
Kallikrein and prekallikrein levels in a large number of congenital clotting deficiencies and abnormalities.
Ketanserin in women with chronic hypertension and underlying thrombophilia.
Lemierre's syndrome complicating bacterial pharyngitis in a patient with undiagnosed factor XII deficiency.
Loss of the largest von Willebrand factor multimers from the plasma of patients with congenital cardiac defects.
Low factor XII level in an individual with Sotos syndrome.
Major abdominal surgery on a patient with factor XII deficiency and lupus anticoagulant: no postoperative DVT as judged by the fibrinogen uptake test.
Management of cardiopulmonary bypass in a patient with congenital factor XII deficiency.
Mitral valve repair and cardiac transplantation in a patient with factor XII deficiency.
MODERATE FACTOR XII DEFICIENCY.
Molecular analysis of factor XII gene in Thai patients with factor XII deficiency.
Molecular Characterization of a Novel Missense Mutation (Asp538Asn) in a Chinese Patient with Factor XII Deficiency.
Molecular Characterization of Cat Factor XII Gene and Identification of a Mutation Causing Factor XII Deficiency in a Domestic Shorthair Cat Colony.
Molecular characterization of coagulation factor XII deficiency in a Japanese family.
Molecular genetic analysis of Korean patients with coagulation factor XII deficiency.
Molecular heterogeneity of Hageman trait (factor XII deficiency): evidence that two of 49 subjects are cross-reacting material positive (CRM+).
Myocardial infarction with normal coronary arteries and factor XII deficiency.
New agents for thromboprotection. A role for factor XII and XIIa inhibition.
New families with factor XII deficiency.
Normal platelet adhesiveness and aggregation in congenital PTA or Hageman factor deficiency.
Novel deleterious mutation in the F12 gene in a Korean family with severe coagulation factor XII deficiency.
Novel mutations in congenital factor XII deficiency.
Oral Mucosa Bleeding Times of Normal Cats and Cats with Chediak-Higashi Syndrome or Hageman Trait (Factor XII Deficiency).
Orbital subperiosteal hemorrhage in a patient with factor VIII and factor XII Deficiency.
Pathogenetic potential of antiphospholipid antibodies.
Periodic painful purpura: Fact or factitious?
Perioperative management of a patient with severe factor XII deficiency.
Perioperative management of cardiac surgery patients with factor XII deficiency - two case reports.
Perioperative use of the Thrombelastograph in patients with inherited bleeding disorders.
Phosphatidylethanolamine participates in the stimulation of the contact system of coagulation by very-low-density lipoproteins.
Plasma prekallikrein: quantitative determination by direct activation with Hageman factor fragment (beta-XIIa).
Plasma thromboplastin antecedent (Factor XI) deficiency in a black family.
Platelet polyphosphates: The nexus of primary and secondary hemostasis.
Polyphosphate is a cofactor for the activation of factor XI by thrombin.
Preoperative bleeding risk assessment with ISTH-BAT and laboratory tests in patients undergoing elective surgery: A prospective cohort study.
Prevalence of factor XII (Hageman factor) deficiency among 426 patients with coronary heart disease awaiting cardiac surgery.
Prevalent factor XII deficiency in cancer patients with isolated aPTT prolongation.
Prolonged activated partial thromboplastin time secondary to factor XII deficiency in two surgical patients.
Pseudo factor XII deficiency and phospholipid antibodies.
Pseudopathologies of hemostasis and dental surgery.
Reaction of blood with artificial surfaces of hemodialyzers. Studies of human blood with platelet defects or coagulation factor deficiencies.
Recurrent reproductive wastage and immunologic factors.
Recurrent subarachnoid haemorrhages in patient with Hageman factor deficiency.
Recurrent thrombosis in a patient with factor XII deficiency.
Reduction of contact activation related fibrinolytic activity in factor XII deficient patients. Further evidence for the role of the contact system in fibrinolysis in vivo.
Relationship between Factor XII deficiency and thrombosis: the debate is still open?
Relationship between kallikrein release and factor XII in normal persons and carriers of the Hageman trait.
Report 2 cases of congenital factor XII deficiency: a rare coagulation disorder.
Resistance to activated protein C: evaluation of three functional assays.
Respective evaluation of the prevalence of haemostasis abnormalities in unexplained primary early recurrent miscarriages. The Nimes Obstetricians and Haematologists (NOHA) Study.
Response of factor XII to DDAVP in patients with Hageman factor deficiency.
Retinal vein occlusion in child with rare mutations in genes for thrombophilia.
Retinal venous thrombosis in a young patient with coagulation factor xii deficiency.
Risk Factors and Outcomes of Recurrent Pregnancy Loss in Japan.
Role of factor XII in thrombin generation and fibrinolysis during cardiopulmonary bypass.
Rosai-Dorfman disease with factor XII deficiency.
Severe Fletcher factor (plasma prekallikrein) deficiency with partial deficiency of Hageman factor (factor XII): report of a case with observation on in vivo and in vitro leukocyte chemotaxis.
So-called "vascular headache of the migraine type": one or more nosological entities?
Subdural haematoma and factor XII deficiency in a Chinese infant.
Subdural hematoma in a patient with Hageman trait--case report.
Superficial migratory thrombophlebitis and factor XII deficiency.
Surgical management in the patient with congenital factor XII deficiency. Report of a case.
Symptomatic combined homozygous factor XII deficiency and heterozygous factor V Leiden. luscaber@tin.it.
The Arthus reaction in cats deficient in Hageman factor (factor XII).
The discrimination of factor XII deficiency and lupus anticoagulant.
The Hageman factor: determinations of its concentration during the neonatal period and presentation of a case of Hageman factor deficiency.
The inheritance pattern of factor XII (Hageman) deficiency in domestic cats.
The old and the new in prekallikrein deficiency: historical context and a family from Argentina with PK deficiency due to a new mutation (Arg541Gln) in exon 14 associated with a common polymorphysm (Asn124Ser) in exon 5.
The possible role of platelets in bypassing the contact phase of blood coagulation.
The prevalence of factor XII deficiency in 103 orally anticoagulated outpatients suffering from recurrent venous and/or arterial thromboembolism.
The Standard Point-of-Care Hemochron Jr. ACT+ Test in Monitoring Heparin Administration for Cardiopulmonary Bypass in Severe Factor XII Deficiency.
Thromboembolism in Hageman trait.
Thrombophilia with a combination of antithrombin III and factor XII deficiency.
Thrombosis in patients with heterozygous and homozygous factor XII deficiency is not explained by the associated presence of factor V Leiden.
Thrombosis in subjects with homozygous and heterozygous factor XII deficiency.
Thrombosis-free surgical procedures in severe (Homozygote) factor XII deficiency: report of four additional cases and literature review.
Thrombus formation on transcatheter ASD occluder device in a patient with coagulation factor XII deficiency.
Transient acquired Factor XII deficiency associated with moderately severe Covid-19 pneumonia.
Transient lupus anticoagulant associated with hypoprothrombinemia and factor XII deficiency following adenovirus infection.
Treatment of hereditary and acquired thrombophilic disorders.
Troubleshooting an isolate prolongation of activated partial thromboplastin time in a patient with acute myocardial infarction-a paradigmatic case report.
Two different incubation times for the activated partial thromboplastin time (APTT): a new criterion for diagnosis of lupus anticoagulant.
Two Novel Mutations (G774A and A1685G) Causing Coagulation Factor XII Deficiency in a Patient with Acute Inferior Myocardial Infarction.
Value of preoperative prothrombin time/partial thromboplastin time as a predictor of postoperative hemorrhage in pediatric patients undergoing tonsillectomy.
Variations of factor XII level during pregnancy in a woman with Hageman factor deficiency.
Varicella and thrombotic complications associated with transient protein C and protein S deficiencies in children.
[3 families with a congenital factor X deficiency, one of them with an associated factor XII deficiency]
[A case of Hageman factor deficiency (factor XII deficiency).]
[A patient with isolated prolongation of aPTT without hemorrhagic diathesis anamnesis: severe, hereditary factor XII deficiency]
[Acute lung injury as a consequence of fresh frozen plasma administration in a patient with factor XII deficiency.]
[Analysis of a consanguineous pedigree affected with hereditary coagulation factor XII deficiency caused by homozygous Gly341Arg mutation].
[Analysis of a pedigree affected with hereditary coagulation factor XII deficiency due to a homozygous 252delAsn deletion of F12 gene].
[Analysis of an abnormal coagulation profile in children qualified for adenoidectomy/tonsilectomy]
[Analysis of an hereditary coagulation factor XII deficiency in a consanguineous pedigree].
[Anesthetic management of a patient with blood coagulation factor XII deficiency]
[Antiphospholipid antibodies in asymptomatic pediatric patients]
[Case of factor XII deficiency with prolonged bleeding time]
[Coagulation factor XII deficiency, a contribution to thrombophilia]
[Congenital deficiency of factor Xii and spontaenous venous thrombosis treated with urokinase]
[Congenital factor XII deficiency: a rare cause of increased activated cephalin time]
[Deep venous thrombosis of the arm revealing a congenital Factor XII deficiency]
[Disorders in the contact phase system of blood coagulation as a cause of increased partial thromboplastin time]
[Effect of oxidized cellulose on fibrin formation and blood platelets]
[Electroimmunoassay of factor XII antigen increased sensitivity by silver staining of immunoprecipitate--factor XII antigen in cases from 9 Japanese families with congenital factor XII deficiency]
[Factor XII (Hageman factor) deficiency: a risk factor for development of thromboembolism. Incidence of factor XII deficiency in patients after recurrent venous or arterial thromboembolism and myocardial infarction]
[Factor XII (HAGEMAN FACTOR)]
[Factor XII deficiency - Hageman trait. Additional diagnostic procedures]
[Factor XII deficiency - Hageman trait. Report of 2 cases]
[Factor XII deficiency and/or anticoagulant treatment at the site of an intracerebral hematoma]
[Factor XII deficiency in two brothers]
[Factor XII deficiency]
[Familial study in congenital Hageman factor deficiency (blood coagulation factor XII)]
[Hageman factor deficiency (factor XII)--hemorrhage or thrombosis?]
[Hageman factor deficiency. Apropos of a case]
[Hageman factor deficiency.]
[HAGEMAN FACTOR DEFICIENCY.]
[Hageman factor deficiency: second case found in Japanese]
[Hemopericardium in hypodermosis in a child with partial factor IX and factor XII deficiencies]
[Hemorrhage after tonsillectomy in a patient with PTA and Hageman factor deficiency: clinico-therapeutic considerations]
[Hemorrhagic diathesis associated with partial factor XII deficiency]
[Importance of Quick, partial thromboplastin time, and Co].
[Is factor XII deficiency a contraindication to surgery?]
[Ischemic stroke in a patient with factor XII (Hageman) deficiency]
[Isolated prolongation of the PTT: 2-year retrospective study]
[Marginal hemophilia: Hageman factor deficiency.]
[Moderate deficiency of Factor XII associated with postoperative deep venous thrombosis]
[Prothrombin fragment 1+2 (F1+2), thrombin-antithrombin III complex(TAT) and thrombophilia parameters in orally anticoagulated patients with inferior vena cava filters]
[Recurrent venous thromboses in hypoplasia of the vena cava inferior and factor XII deficiency]
[Review of patients studied for coagulopathy in a Hematology/Oncology unit].
[Sacroiliitis in familial Mediterranean fever]
[Study of a family with factor XII deficiency]
[Successes and failures of the activated partial thromboplastin time in the preoperative evaluation]
[The genetics of factor XII deficiency]
[Thrombophlebitis and pulmonary embolism in congenital factor XII deficiency]
[Tonsillectomy in factor XII deficiency]
[Unsuspected prolonged activated partial thromboplastin time in emergency surgery. Diagnostic and therapeutic guide]
[Use of chromogenic substrates in the clarification of disorders in the early stages of blood coagulation]
Factor XIII Deficiency
Inherited bleeding disorders in Indian women with menorrhagia.
Fetal Macrosomia
Comparison of factor XII levels in gestational diabetes, fetal macrosomia, and healthy pregnancies.
Gastrointestinal Hemorrhage
Factor XII and partial prekallikrein deficiencies in a dog with recurrent gastrointestinal hemorrhage.
Gastrointestinal Neoplasms
Activation of the contact system in ascites from patients with gastrointestinal cancer.
Genetic Diseases, Inborn
Mutation of the angiopoietin-1 gene (ANGPT1) associates with a new type of hereditary angioedema.
Glomerulonephritis
Minimal-change glomerulonephritis associated with circulating anticoagulant to factor XII.
Glomerulonephritis, IGA
Glomerular deposition of Hageman factor in IgA nephropathy.
Glomerulonephritis, Membranous
Hageman factor deposition in membranous glomerulopathy.
Gout
Classic gout in Hageman factor (Factor XII) deficiency.
Factor XII deficiency in a man with gout and angioimmunoblastic lymphadenopathy.
Granuloma
The monocyte-macrophage system in granulomatous inflammation.
Heart Arrest
Activation of Hageman factor by cardiac arrest.
Heart Diseases
FXII levels, FXIIa-like activities and kallikrein activities in normal subjects and patients undergoing cardiac surgery.
New and old cardiovascular risk factors: C-reactive protein, homocysteine, cysteine and von Willebrand factor increase risk, especially in smokers.
Heart Septal Defects, Ventricular
Aortic valve replacement and ventricular septal defect repair in factor XII deficiency: An anesthetic challenge.
Hematologic Neoplasms
Elevated extracellular trap formation and contact system activation in acute leukemia.
Pretransplant factor XII levels correlate with prognosis in patients undergoing autologous graft for hematological malignancies.
Hematoma, Subdural
Subdural hematoma in a patient with Hageman trait--case report.
Hematoma, Subdural, Chronic
Subdural hematoma in a patient with Hageman trait--case report.
Hemophilia A
A female hemophilia A combined with hereditary coagulation factor XII deficiency: a case report.
Additional factor XII (Hageman factor) deficiency in hemophilia A and in von Willebrand syndrome.
Assessment of Actin FS and Actin FSL sensitivity to specific clotting factor deficiencies.
Cardiopulmonary bypass in patients with pre-existing coagulopathy.
Clinical relevance of isolated prolongation of the activated partial thromboplastin time in a cohort of adults undergoing surgical procedures.
Fibrin formation, fibrinopeptide A release, and platelet thrombus dimensions on subendothelium exposed to flowing native blood: greater in factor XII and XI than in factor VIII and IX deficiency.
Hemophilia A in a phenotypic female with normal male karyotype associated with a low factor XII level.
Hemophilia D factor (factor XII), red-cell deformability and platelet aggregates in raptors.
Identifying hypocoagulable states with a modified global assay of overall haemostasis potential in plasma.
In vivo bypass of hemophilia A coagulation defect by factor XIIa implant.
Perioperative use of the Thrombelastograph in patients with inherited bleeding disorders.
[Infective morbidity of replacement therapy in congenital coagulation deficiencies and its effects on demand of coagulation factors]
[Marginal hemophilia: Hageman factor deficiency.]
[Unsuspected prolonged activated partial thromboplastin time in emergency surgery. Diagnostic and therapeutic guide]
Hemophilia B
Activation of factor VII during alimentary lipemia occurs in healthy adults and patients with congenital factor XII or factor XI deficiency, but not in patients with factor IX deficiency.
Additional factor XII (Hageman factor) deficiency in hemophilia A and in von Willebrand syndrome.
Combined von Willebrand's disease and factor XII deficiency in a carrier of haemophilia B.
Fibrin formation, fibrinopeptide A release, and platelet thrombus dimensions on subendothelium exposed to flowing native blood: greater in factor XII and XI than in factor VIII and IX deficiency.
[Hemophilia B (factor IX deficiency) with concomitant factor XII degradation in a male crossbreed cat]
[Infective morbidity of replacement therapy in congenital coagulation deficiencies and its effects on demand of coagulation factors]
[Review of patients studied for coagulopathy in a Hematology/Oncology unit].
Hemorrhagic Disorders
Factor XI contributes to thrombin generation in the absence of factor XII.
Thromboembolism in Hageman trait.
[A patient with isolated prolongation of aPTT without hemorrhagic diathesis anamnesis: severe, hereditary factor XII deficiency]
[Hemorrhagic diathesis associated with partial factor XII deficiency]
Hemorrhagic Stroke
Factor XII as a Risk Marker for Hemorrhagic Stroke: A Prospective Cohort Study.
Hemostatic Disorders
Factor XII defect and hemorrhage. Evidence for a new type of hereditary hemostatic disorder.
Hepatitis
Hageman factor, high molecular weight kininogen, and prekallikrein in chronic liver disease.
Hepatitis B
Molecular structure alteration of IgG increased anticomplementary activity of intravenous immunoglobulin.
Hepatitis, Chronic
Hageman factor, high molecular weight kininogen, and prekallikrein in chronic liver disease.
Hereditary Angioedema Type III
Defective glycosylation of coagulation factor XII underlies hereditary angioedema type III.
Factor XII gene missense mutation Thr328Lys in an Arab family with hereditary angioedema type III.
Increased activity of coagulation factor XII (Hageman factor) causes hereditary angioedema type III.
Missense mutation Thr309Lys in the coagulation factor XII gene in a Spanish family with hereditary angioedema type III.
Repeated attacks of type III hereditary angioedema with factor XII mutation during pregnancy.
Hereditary Angioedema Types I and II
Angioedema.
Histiocytosis, Sinus
Rosai-Dorfman disease with factor XII deficiency.
HIV Infections
Effect of antiretroviral therapy on hemostasis in Brazilian pregnant women with HIV infection.
Hypercholesterolemia
Synergistic association between hypercholesterolemia and the C46T factor XII polymorphism for developing premature myocardial infarction.
Hyperhomocysteinemia
Anticoagulant therapy and pregnancy.
Hyperlipidemias
Activation of factor VII during alimentary lipemia occurs in healthy adults and patients with congenital factor XII or factor XI deficiency, but not in patients with factor IX deficiency.
In vivo demonstration in humans that large postprandial triglyceride-rich lipoproteins activate coagulation factor VII through the intrinsic coagulation pathway.
[A case of pituitary dwarfism with hyperlipemia, factor XII and XI deficiency, and low level of NK activity]
Hyperlipoproteinemia Type II
Participation of Hageman factor dependent pathways in human disease states.
Hyperlipoproteinemias
Activation of the kallikrein system in hyperbetalipoproteinemia.
Hyperprolactinemia
Hyperprolactinemia and reduction in plasma titers of Hageman factor, prekallikrein, and high molecular weight kininogen in patients with acute myocardial infarction.
Hypersensitivity
Activation of plasma Hageman factor and kallikrein in ongoing allergic reactions in the skin.
Comparing Pathways of Bradykinin Formation in Whole Blood From Healthy Volunteers and Patients With Hereditary Angioedema Due to C1 Inhibitor Deficiency.
Inhibition of Df-protease--induced kinin release by synthetic inhibitors.
Pathogenic mechanisms of bradykinin mediated diseases: dysregulation of an innate inflammatory pathway.
Hypersensitivity, Delayed
Carrageenan and delayed hypersensitivity. II. Activation of Hageman factor by carrageenan and its possible significance.
Hypersensitivity, Immediate
Anaphylactic release of a prekallikrein activator from human lung in vitro.
Hypertension
Factor XII (Hageman factor) is a missing link between stress and hypercoagulability and plays an important role in the pathophysiology of ischemic stroke.
The effects of two types of renin-angiotensin system inhibitors on the hypertension induced by new pressor protein associated with beta-factor XIIa in rats.
[Blood coagulation changes in hypo- and hypertensive neurocirculatory dystonia under the influence of physical load]
Hyperthyroidism
Contact system activation and high thrombin generation in hyperthyroidism.
Hypoprothrombinemias
Transient lupus anticoagulant associated with hypoprothrombinemia and factor XII deficiency following adenovirus infection.
Hypotension
A complete factor XII deficiency does not affect coagulopathy, inflammatory responses, and lethality, but attenuates early hypotension in endotoxemic mice.
Acute hypotension due to platelet serotonin-induced chemoreflexes after intravenous injection of dextran sulfate in the rabbit.
Acute intracranial hypertension occurring during infusion of stable plasma protein solution.
An animal model for the detection of hypotensive side effects of immunoglobulin preparations.
Bradykinin and cysteinyl leukotriene concentrations in cell-salvaged blood before and after passage through negatively charged filters during clinical use in cancer patients: a pilot study.
Hypotension associated with prekallikrein activator (Hageman-factor fragments) in plasma protein fraction.
Inhibition of factor XII in septic baboons attenuates the activation of complement and fibrinolytic systems and reduces the release of interleukin-6 and neutrophil elastase.
Naloxone attenuates the hypotension induced by Hageman factor.
Plasma contact system activation drives anaphylaxis in severe mast cell-mediated allergic reactions.
Plasmin-mediated activation of contact system in response to pharmacological thrombolysis.
Prolonged activated partial thromboplastin time and deficiency of high molecular weight kininogen in brown Norway rat mutant (Katholiek strain).
Protection by recombinant alpha 1-antitrypsin Ala357 Arg358 against arterial hypotension induced by factor XII fragment.
The contact system contributes to hypotension but not disseminated intravascular coagulation in lethal bacteremia. In vivo use of a monoclonal anti-factor XII antibody to block contact activation in baboons.
[Blood coagulation changes in hypo- and hypertensive neurocirculatory dystonia under the influence of physical load]
[Role of bradykinin in hypotension induced by the active factor derived from factor XII]
Hypothyroidism
Coagulation and fibrinolysis in thyroid disease.
Idiopathic Pulmonary Fibrosis
Heparan Sulfate Proteoglycans Mediate Factor XIIa Binding to the Cell Surface.
Immunoblastic Lymphadenopathy
Factor XII deficiency in a man with gout and angioimmunoblastic lymphadenopathy.
Infections
Activation of protein mediators of inflammation and evidence for endotoxemia in Borrelia recurrentis infection.
Bmal1 Regulates Coagulation Factor Biosynthesis in Mouse Liver in Streptococcus oralis Infection.
Contact System Activation in Plasma from Dengue Patients Might Harness Endothelial Virus Replication through the Signaling of Bradykinin Receptors.
CpaA Is a Glycan-Specific Adamalysin-like Protease Secreted by Acinetobacter baumannii That Inactivates Coagulation Factor XII.
Disseminated intravascular coagulopathy during experimental pneumococcal sepsis: studies in normal and asplenic rhesus monkeys.
Hageman complement and factor.
Hageman factor dependent activation and its relationship to lethal Pseudomonas aeruginosa burn wound infections.
Hemostatic/fibrinolytic protein changes in C3H/HeN mice infected with Rickettsia conorii--a model for Rocky Mountain spotted fever.
Thrombosis and Hemostatic Abnormalities in Hematological Malignancies.
[Anesthetic management of a patient with blood coagulation factor XII deficiency]
Inferior Wall Myocardial Infarction
Two Novel Mutations (G774A and A1685G) Causing Coagulation Factor XII Deficiency in a Patient with Acute Inferior Myocardial Infarction.
Intellectual Disability
Cerebral visual impairment and intellectual disability caused by PGAP1 variants.
Intracranial Embolism
Factor XIIa as a Novel Target for Thrombosis: Target Engagement Requirement and Efficacy in a Rabbit Model of Microembolic Signals.
Ischemic Stroke
Antigen levels of coagulation factor XII, coagulation factor XI and prekallikrein, and the risk of myocardial infarction and ischemic stroke in young women.
Coagulation factor XII, XI, and VIII activity levels and secondary events after first ischemic stroke.
COU254, a specific 3-carboxamide-coumarin inhibitor of coagulation factor XII, does not protect mice from acute ischemic stroke.
Enhanced cortical reperfusion protects coagulation factor XII-deficient mice from ischemic stroke as revealed by high-field MRI.
Factor XII (Hageman factor) is a missing link between stress and hypercoagulability and plays an important role in the pathophysiology of ischemic stroke.
Independent ischemic stroke risk factors in older Americans: a systematic review.
Meta-Analysis of Factor V, Factor VII, Factor XII, and Factor XIII-A Gene Polymorphisms and Ischemic Stroke.
The Coagulation Factor XIIa Inhibitor rHA-Infestin-4 Improves Outcome after Cerebral Ischemia/Reperfusion Injury in Rats.
[Ischemic stroke in a patient with factor XII (Hageman) deficiency]
Joint Diseases
Classic gout in Hageman factor (Factor XII) deficiency.
Relative contribution of contact and complement activation to inflammatory reactions in arthritic joints.
Kidney Diseases
Clotting activities and antigen concentrations of contact factors in kidney disease.
Kidney Failure, Chronic
A new enzyme-linked immunosorbent assay recognizing both rat and human activated coagulation Factor XII (FXIIa).
Coagulation Factor XIIa-kinin-mediated contribution to hypertension of chronic kidney disease.
Contact Activation Inhibitor, AB023, in Heparin-Free Hemodialysis: Results of a Randomized Phase 2 Clinical Trial.
Extrinsic coagulation factors and tissue factor pathway inhibitor in end-stage chronic renal failure.
Intrinsic coagulation pathway in end-stage renal disease associated with spinal cord injury treated with hemodialysis.
Lemierre Syndrome
Lemierre's syndrome complicating bacterial pharyngitis in a patient with undiagnosed factor XII deficiency.
Leukemia
Elevated extracellular trap formation and contact system activation in acute leukemia.
Leukocytosis
["Lymphoid" blastic transformation in chronic myelogenous leukemia. Report of three cases (author's transl)]
Leukoencephalopathies
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy with severe factor XII deficiency.
Invited Commentary. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy with severe factor XII deficiency.
Liver Diseases
Acquired inhibitors to the coagulation factor XII associated with liver disease.
Clinical relevance of isolated prolongation of the activated partial thromboplastin time in a cohort of adults undergoing surgical procedures.
Hageman factor, high molecular weight kininogen, and prekallikrein in chronic liver disease.
The contact system.
The role of Hageman factor in disseminated intravascular coagulation induced by septicemia, neoplasia, or liver disease.
Liver Failure
Hageman factor, high molecular weight kininogen, and prekallikrein in chronic liver disease.
Lung Diseases
Activation of factor XII by tobacco glycoprotein.
Lupus Erythematosus, Systemic
Antibodies to factor XII and recurrent fetal loss in patients with the anti-phospholipid syndrome.
Antibodies to factor XII: a possible predictive marker for recurrent foetal loss.
Circulating anticoagulant against Factor XII and platelet antibodies in systemic lupus erythematosus.
Factor XII autoantibodies as a novel marker for thrombosis and adverse obstetric history in patients with systemic lupus erythematosus.
Factor XII deficiency with systemic lupus erythematosus. Biological implications.
Low plasma factor XII activity in patients with systemic lupus erythematosus and a lupus anticoagulant.
Studies on a circulating anticoagulant in procainamide-induced lupus erythematosus.
Thrombin-activatable fibrinolysis inhibitor and activated factor XII in patients with systemic lupus erythematosus.
Lymphoma, B-Cell
Factor XII auto-antibodies present in a patient with a B-cell lymphoma.
Melanoma
Proteolytic activation of tissue plasminogen activator by plasma and tissue enzymes.
Migraine Disorders
Arginine esterase in cerebrospinal fluid and pro-arginine esterase in plasma from patients with migraine.
Mitral Valve Stenosis
Huge left atrial thrombus with mitral stenosis in congenital factor XII deficiency.
Mouth Neoplasms
Increased risk for oral cancer is associated with coagulation factor XIII but not with factor XII.
Multiple Myeloma
Elevated extracellular trap formation and contact system activation in acute leukemia.
Multiple Sclerosis
Coagulation Factor XII Levels and Intrinsic Thrombin Generation in Multiple Sclerosis.
The Coagulation Factors Fibrinogen, Thrombin, and Factor XII in Inflammatory Disorders-A Systematic Review.
Myelodysplastic Syndromes
Elevated extracellular trap formation and contact system activation in acute leukemia.
Myocardial Infarction
Activated factor 12 (FXIIa) predicts recurrent coronary events after an acute myocardial infarction.
Acute coronary syndromes do not promote prolonged in vivo FXII-dependent prothrombotic activity.
Antigen levels of coagulation factor XII, coagulation factor XI and prekallikrein, and the risk of myocardial infarction and ischemic stroke in young women.
Augmented Hageman factor and prolactin titers, enhanced cold activation of factor VII, and spontaneous shortening of prothrombin time in survivors of myocardial infarction.
Changes in coagulation factors following acute myocardial infarction in man.
Changes in tissue factor and activated factor XII following an acute myocardial infarction were uninfluenced by high doses of n-3 polyunsaturated fatty acids.
Comparison of novel hemostatic factors and conventional risk factors for prediction of coronary heart disease.
Concomitant ST-elevation myocardial infarction and deep vein thrombosis in a patient with severe factor XII deficiency: case report and review of the literature.
Deep venous thrombosis and previous myocardial infarction in mild factor XII deficiency: a risk factor for both venous and arterial thrombosis.
Defective intrinsic fibrinolytic activity in a patient with severe factor XII-deficiency and myocardial infarction.
Elevated levels of plasma prekallikrein, high molecular weight kininogen and factor XI in coronary heart disease.
Factor XII deficiency in a man with gout and angioimmunoblastic lymphadenopathy.
Hageman factor and risk of myocardial infarction in middle-aged men.
Hyperprolactinemia and reduction in plasma titers of Hageman factor, prekallikrein, and high molecular weight kininogen in patients with acute myocardial infarction.
Levels of activated FXII in survivors of myocardial infarction--association with circulating risk factors and extent of coronary artery disease.
Levels of intrinsic coagulation factors and the risk of myocardial infarction among men: Opposite and synergistic effects of factors XI and XII.
Measurement of activated factor XII in health and disease.
Myocardial infarction with normal coronary arteries and factor XII deficiency.
Prevalence of factor V Leiden (APCR) and other inherited thrombophilias in young patients with myocardial infarction and normal coronary arteries.
Prevalence of factor XII (Hageman factor) deficiency among 426 patients with coronary heart disease awaiting cardiac surgery.
Synergism between factor XII -4C>T and factor XIII Val34Leu polymorphisms in fibrinolytic therapy in acute myocardial infarction.
Synergistic association between hypercholesterolemia and the C46T factor XII polymorphism for developing premature myocardial infarction.
The prevalence of factor XII deficiency in 103 orally anticoagulated outpatients suffering from recurrent venous and/or arterial thromboembolism.
[Factor XII (Hageman factor) deficiency: a risk factor for development of thromboembolism. Incidence of factor XII deficiency in patients after recurrent venous or arterial thromboembolism and myocardial infarction]
Myocardial Ischemia
Effect of varying the ratio of n-6 to n-3 fatty acids by increasing the dietary intake of alpha-linolenic acid, eicosapentaenoic and docosahexaenoic acid, or both on fibrinogen and clotting factors VII and XII in persons aged 45-70 y: the OPTILIP study.
The impact of cardiac ischemia and reperfusion on markers of activated haemostasis and fibrinolysis during cardiopulmonary bypass: comparison of plasma levels in arterial and coronary venous blood.
Neoplasm Metastasis
The interaction of coagulation factor XII and monocyte/macrophages mediating peritoneal metastasis of epithelial ovarian cancer.
Neoplasms
Cardiopulmonary bypass in patients with pre-existing coagulopathy.
Coagulation and oxidative stress plasmatic levels in a type 2 diabetes population.
Elevated extracellular trap formation and contact system activation in acute leukemia.
Extrinsic-pathway activation in cancer with high factor VIIa and tissue factor.
Factor XII blockade inhibits aortic dilatation in angiotensin II-infused apolipoprotein E-deficient mice.
Impaired bradykinin response to ischaemia and exercise in patients with mild congestive heart failure during angiotensin-converting enzyme treatment. Relationships with endothelial function, coagulation and inflammation.
Kinin-generating cascade in advanced cancer patients and in vitro study.
Prekallikrein, HMW-kininogen and factor XII in various disease states.
Prevalent factor XII deficiency in cancer patients with isolated aPTT prolongation.
Recent updates in the clinical trials of therapeutic monoclonal antibodies targeting cytokine storm for the management of COVID-19.
Studies on components of the contact phase system in patients with advanced gastrointestinal cancer.
The role of Hageman factor in disseminated intravascular coagulation induced by septicemia, neoplasia, or liver disease.
Thromboembolic Complications in Malignant Haematological Disorders.
Thrombosis and Hemostatic Abnormalities in Hematological Malignancies.
[Anesthetic management of a patient with deficiency of congenital coagulation factor XII]
[Effect of compound Chinese drug bailong on the expression of tumor suppressor genes and relationship with prekallikrein activator signal pathway in human gastric carcinoma BGC82-3 cell line]
Nephritis
Hageman factor in experimental nephrotoxic nephritis in the rabbit.
Plasma activity of contact coagulation factors in patients with IgA nephritis.
Nephrosis
[Acquired deficiency of factor XII and antithrombin III (AT III) in nephroses of children. Preliminary results]
Nephrotic Syndrome
Acquired factor XII Deficiency in a patient with nephrotic syndrome.
Activation of Hageman factor in the nephrotic syndrome.
Adult nephrotic syndrome and acquired coagulopathies: Hageman factor deficiency.
Decreased factor XII activity in a child with nephrotic syndrome and thromboembolic complications.
Deficiency and urinary losses of factor XII in adult nephrotic syndrome.
Deficiency of Hageman factor (factor XII) in patients with the nephrotic syndrome.
Factor XII and other hemostatic protein abnormalities in nephrotic syndrome patients.
Immunoquantitation of Hageman factor in urine and plasma of children with nephrotic syndrome.
Involvement of hemostasis during an autoimmune glomerulonephritis induced by mercuric chloride in brown Norway rats.
Mechanism and significance of kinin formation in nephrotic syndrome.
Participation of Hageman factor dependent pathways in human disease states.
Urinary excretion of Hageman factor (factor XII) and the presence of nonfunctional Hageman factor in the nephrotic syndrome.
Neuroinflammatory Diseases
Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cells.
Obesity
Contact activated kallikrein generation is reduced six months after gastric bypass.
Obstetric Labor, Premature
Factor XII deficiency and pregnancy.
Optic Neuritis
A new headache syndrome? Headache resembling cluster headache (Horton's headache), with recurring bouts of homolateral retrobulbar neuritis, partial factor XII deficiency, bleeding tendency and a heterolateral convulsive episode.
So-called "vascular headache of the migraine type": one or more nosological entities?
Osteoarthritis
Relative contribution of contact and complement activation to inflammatory reactions in arthritic joints.
Osteomyelitis
Surgical management in the patient with congenital factor XII deficiency. Report of a case.
Pancreatitis
Infusion of C1-inhibitor plasma concentrate prevents hyperamylasemia induced by endoscopic sphincterotomy.
Peritoneal lavage efficiently eliminates protease-alpha-2-macroglobulin complexes and components of the contact system from the peritoneal cavity in patients with severe acute pancreatitis.
Paralysis
Factor XII deficiency and recurrent sixth nerve palsy.
Paraplegia
[Two siblings with familial spastic paraplegia associated with decreased levels of factor XII]
Paroxysmal Hemicrania
So-called "vascular headache of the migraine type": one or more nosological entities?
Pericardial Effusion
[Hemopericardium in hypodermosis in a child with partial factor IX and factor XII deficiencies]
Periodontitis
Thrombin and bradykinin enhance prostaglandin production in human peripheral blood monocytes.
Peripheral Arterial Disease
The Functional Promoter Polymorphism of the Coagulation Factor XII Gene is not Associated With Peripheral Arterial Disease.
Pharyngitis
Lemierre's syndrome complicating bacterial pharyngitis in a patient with undiagnosed factor XII deficiency.
plasma kallikrein deficiency
A comparison of the effects of factor XII deficiency and prekallikrein deficiency on thrombus formation.
A hitherto undescribed plasma factor acting at the contact phase of blood coagulation (Flaujeac factor): case report and coagulation studies.
Activated partial thromboplastin time and minor coagulopathies.
Evidence against collagen activation of platelet-associated factor XI as a mechanism for initiating intrinsic clotting.
Factor XII and partial prekallikrein deficiencies in a dog with recurrent gastrointestinal hemorrhage.
Fletcher factor deficiency. A diminished rate of Hageman factor activation caused by absence of prekallikrein with abnormalities of coagulation, fibrinolysis, chemotactic activity, and kinin generation.
Pathophysiology of thrombophilic states.
Prekallikrein deficiency: the characteristic normalization of the severely prolonged aPTT following increased preincubation time is due to autoactivation of factor XII.
Severe Prekallikrein Deficiency Associated with Low Level of Factor XII: A Case Report.
[Isolated prolongation of the PTT: 2-year retrospective study]
Pneumonia
Coagulation factor XI improves host defence during murine pneumonia-derived sepsis independent of factor XII activation.
Transient acquired Factor XII deficiency associated with moderately severe Covid-19 pneumonia.
Pneumonia, Ventilator-Associated
CpaA Is a Glycan-Specific Adamalysin-like Protease Secreted by Acinetobacter baumannii That Inactivates Coagulation Factor XII.
Polycythemia Vera
Activation of the coagulation system in polycythemia vera.
Participation of Hageman factor dependent pathways in human disease states.
[Polycythemia vera with an inhibitor against factor XII]
Pre-Eclampsia
A serial study of coagulation factors XII, XI and X in plasma in normal pregnancy and in pregnancy complicated by pre-eclampsia.
Fetal corticotrophin-releasing hormone mRNA, but not phosphatidylserine-exposing microparticles, in maternal plasma are associated with factor VII activity in pre-eclampsia.
Prostatic Neoplasms
The polyphosphate-factor XII pathway drives coagulation in prostate cancer-associated thrombosis.
The polyphosphate/factor XII pathway in cancer-associated thrombosis: novel perspectives for safe anticoagulation in patients with malignancies.
Protein C Deficiency
Anticoagulant therapy and pregnancy.
Autologous bone marrow transplantation and factor XII, factor VII, and protein C deficiencies. Report of a new association and its possible relationship to endothelial cell injury.
Risk factors and long-term follow-up of patients with the immune type of heparin-induced thrombocytopenia.
Varicella and thrombotic complications associated with transient protein C and protein S deficiencies in children.
[Prothrombin fragment 1+2 (F1+2), thrombin-antithrombin III complex(TAT) and thrombophilia parameters in orally anticoagulated patients with inferior vena cava filters]
Protein S Deficiency
Anticoagulant therapy and pregnancy.
Cardiopulmonary bypass in patients with pre-existing coagulopathy.
Deep venous thrombosis, protein S deficiency and homozygous Factor XII 46T mutation.
Patent foramen ovale and prothrombotic markers in young stroke patients.
Risk Factors and Outcomes of Recurrent Pregnancy Loss in Japan.
[Prothrombin fragment 1+2 (F1+2), thrombin-antithrombin III complex(TAT) and thrombophilia parameters in orally anticoagulated patients with inferior vena cava filters]
protein-glutamine gamma-glutamyltransferase deficiency
Inherited bleeding disorders in Indian women with menorrhagia.
Pulmonary Embolism
Platelet polyphosphates are proinflammatory and procoagulant mediators in vivo.
[Thrombophlebitis and pulmonary embolism in congenital factor XII deficiency]
Pulmonary Fibrosis
The fibrogenic actions of the coagulant and plasminogen activation systems in pulmonary fibrosis.
Pulmonary Valve Stenosis
[Combined aortic and pulmonary valve stenosis, changes in primary hemostasis and partial deficiency of factor XII in Noonan's syndrome]
Purpura, Thrombocytopenic
Circulating anticoagulant against Factor XII and thrombocytopenic purpura.
Purpura, Thrombocytopenic, Idiopathic
Cardiopulmonary bypass in patients with pre-existing coagulopathy.
Renal Insufficiency
Activation of coagulation and fibrinolysis in childhood diarrhoea-associated haemolytic uraemic syndrome.
An enzyme-linked immunosorbent assay (ELISA) for the measurement of activated factor XII (Hageman factor) in human plasma.
Reperfusion Injury
Selective depletion of plasma prekallikrein or coagulation factor XII inhibits thrombosis in mice without increased risk of bleeding.
Retinal Perforations
High Subretinal Fluid Procoagulant Activity in Rhegmatogenous Retinal Detachment.
Retinal Vein Occlusion
Factor XII deficiency and central retinal vein occlusion.
Factor XII deficiency: a thrombophilic risk factor for retinal vein occlusion.
Schistosomiasis
The coagulation profile in hepatosplenic schistosomiasis.
Sepsis
Activation of the contact system of plasma proteolysis in the adult respiratory distress syndrome.
Coagulation factor XI improves host defence during murine pneumonia-derived sepsis independent of factor XII activation.
Coagulation system and platelets are fully activated in uncomplicated sepsis.
Ecotin is a potent inhibitor of the contact system proteases factor XIIa and plasma kallikrein.
Expression, refolding, and activation of the catalytic domain of human blood coagulation factor XII.
Factor XII Activation Promotes Platelet Consumption in the Presence of Bacterial-Type Long-Chain Polyphosphate In Vitro and In Vivo.
Hemostatic abnormalities and the severity of illness in patients at the onset of clinically defined sepsis. Possible indication of the degree of endothelial cell activation?
Inhibition of factor XI activation attenuates inflammation and coagulopathy while improving the survival of mouse polymicrobial sepsis.
Measurement of activated factor XII in health and disease.
Posttraumatic acute cholecystitis. Relationship to the initial trauma.
Role of Hageman factor/kallikrein-kinin system in pseudomonal elastase-induced shock model.
The contact system proteases play disparate roles in streptococcal sepsis.
The role of Hageman factor in disseminated intravascular coagulation induced by septicemia, neoplasia, or liver disease.
[Contemporary views on the problem of sepsis]
Shock, Septic
Measurement of activated factor XII in health and disease.
Participation of Hageman factor dependent pathways in human disease states.
Plasma kallikrein-kinin system in patients with uncomplicated sepsis and septic shock--comparison with cardiogenic shock.
Quantification of plasma factor XIIa-Cl(-)-inhibitor and kallikrein-Cl(-)-inhibitor complexes in sepsis.
Role of alpha-2-macroglobulin and bacterial elastase in guinea-pig pseudomonal septic shock.
Studies on components of the plasma kallikrein-kinin system in plasma samples from normal individuals and patients with septic shock.
Shwartzman Phenomenon
Activation of Hageman factor by ellagic acid and the generalized Shwartzman reaction.
Consumption of Hageman factor activity in the generalized Shwartzman reaction induced by liquoid. Its prevention by inhibition of Hageman factor activation.
Hageman factor activation in the generalized Shwartzman reaction induced by endotoxin.
Sinus Thrombosis, Intracranial
Cerebral venous sinus thrombosis in infancy and childhood: role of genetic and acquired risk factors of thrombophilia.
Sotos Syndrome
Low factor XII level in an individual with Sotos syndrome.
Spastic Paraplegia, Hereditary
A novel factor XII mutation, FXII R84P, causing factor XII deficiency in a patient with hereditary spastic paraplegia.
Spinal Cord Injuries
Intrinsic coagulation pathway in end-stage renal disease associated with spinal cord injury treated with hemodialysis.
Stroke
Factor XII Concentrations and Risk of Intracerebral Haemorrhage. A Prospective Case-Referent Study.
Inhibition of Factor XII-Mediated Activation of Factor XI Provides Protection Against Experimental Acute Ischemic Stroke in Mice.
Ischaemic stroke: a thrombo-inflammatory disease ?
Ischemic stroke and traumatic brain injury: the role of the kallikrein-kinin system.
Molecular mechanisms of thrombus formation in ischemic stroke: novel insights and targets for treatment.
Role of the kallikrein-kinin system in traumatic brain injury.
The Coagulation Factor XIIa Inhibitor rHA-Infestin-4 Improves Outcome after Cerebral Ischemia/Reperfusion Injury in Rats.
The plasma kallikrein-kinin system and risk of cardiovascular disease in men.
Thrombo-inflammation in acute ischaemic stroke - implications for treatment.
[Acute ischemic stroke : New approaches to antithrombotic treatment.]
Thrombasthenia
Availability of platelet Factor 3 and activation of factor XII in thrombasthenia.
Reaction of blood with artificial surfaces of hemodialyzers. Studies of human blood with platelet defects or coagulation factor deficiencies.
Thrombocytopenia
Cardiopulmonary bypass in patients with pre-existing coagulopathy.
[Review. Endotoxins and blood coagulation]
Thrombocytosis
Essential thrombocytosis accompanied by coagulation factor XII deficiency: a case report.
Thromboembolism
Clinical implications of factor XII deficiency.
Factor XII deficiency and pregnancy.
Free Fatty Acids in CSF and Neurological Clinical Scores: Prognostic Value for Stroke Severity in ICU.
Huge left atrial thrombus with mitral stenosis in congenital factor XII deficiency.
The prevalence of factor XII deficiency in 103 orally anticoagulated outpatients suffering from recurrent venous and/or arterial thromboembolism.
The prevalence of heterozygous F12 mutations in Chinese population and its relevance to incidents of thrombosis.
Thromboembolism and bleeding tendency in congenital factor XII deficiency--a study on 74 subjects from 14 Swiss families.
Thrombus formation on transcatheter ASD occluder device in a patient with coagulation factor XII deficiency.
Transcatheter closure of atrial septal defect and patent foramen ovale with ASDOS device (a multi-institutional European trial).
[Factor XII (Hageman factor) deficiency: a risk factor for development of thromboembolism. Incidence of factor XII deficiency in patients after recurrent venous or arterial thromboembolism and myocardial infarction]
[Recurrent venous thromboses in hypoplasia of the vena cava inferior and factor XII deficiency]
Thromboinflammation
Biological basis and pathological relevance of microvascular thrombosis.
Thrombophilia
A comprehensive insight into the role of zinc deficiency in the renin-angiotensin and kinin-kallikrein system dysfunctions in COVID-19 patients.
Acquired factor XII deficiency in a woman with recurrent pregnancy loss: working on a differential diagnosis in a single case.
Activated factor 12 (FXIIa) predicts recurrent coronary events after an acute myocardial infarction.
Clinical importance of prothrombotic risk factors in pediatric patients with malignancy--impact of central venous lines.
Factor XII (Hageman factor) is a missing link between stress and hypercoagulability and plays an important role in the pathophysiology of ischemic stroke.
Homozygosity of the T allele of the 46 C->T polymorphism in the F12 gene is a risk factor for ischemic stroke in the Spanish population.
In vivo role of factor XII (Hageman factor) in hypercoagulability and fibrinolysis.
Multiplex primer extension reaction and capillary electrophoresis to study the frequency of thrombophilia-related mutations in a spanish population.
Plasma markers of hypercoagulability in patients with serious infections and risk of septic shock.
Rapid factor XII (46C-->T) genotyping by fluorescence resonance energy transfer in patients with coronary artery disease or thrombophilia.
Retinal vein occlusion in child with rare mutations in genes for thrombophilia.
Retinal venous thrombosis in a young patient with coagulation factor xii deficiency.
Should factor XII assays be included in thrombophilia screening?
Stearic acid, clotting, and thrombosis.
Thrombophilia with a combination of antithrombin III and factor XII deficiency.
Treatment of hereditary and acquired thrombophilic disorders.
[Coagulation factor XII deficiency, a contribution to thrombophilia]
[Prothrombin fragment 1+2 (F1+2), thrombin-antithrombin III complex(TAT) and thrombophilia parameters in orally anticoagulated patients with inferior vena cava filters]
Thrombophlebitis
Superficial migratory thrombophlebitis and factor XII deficiency.
[Thrombophlebitis and pulmonary embolism in congenital factor XII deficiency]
Thrombosis
A comparison of the effects of factor XII deficiency and prekallikrein deficiency on thrombus formation.
A new textured polyphosphazene biomaterial with improved blood coagulation and microbial infection responses.
A novel anticoagulant purified from fish protein hydrolysate inhibits factor XIIa and platelet aggregation.
A possible new role for A? in vascular and inflammatory dysfunction in Alzheimer's disease.
A quantitative-trait locus in the human factor XII gene influences both plasma factor XII levels and susceptibility to thrombotic disease.
A role for factor XIIa-mediated factor XI activation in thrombus formation in vivo.
Activated factor 12 (FXIIa) predicts recurrent coronary events after an acute myocardial infarction.
Activation of coagulation during treatment with haemodialysis.
Activation of Hageman factor and initiation of hepatic vein thrombosis in the hyperlipemic rat.
Aegyptin inhibits collagen-induced coagulation activation in vitro and thromboembolism in vivo.
An update on the pharmaceutical management of thrombosis.
Animal Models of Thrombosis From Zebrafish to Nonhuman Primates: Use in the Elucidation of New Pathologic Pathways and the Development of Antithrombotic Drugs.
Antithrombotic Effect of shRNA Target F12 Mediated by Adeno-Associated Virus.
Antithrombotic potential of the contact activation pathway.
Assembly, activation, and physiologic influence of the plasma kallikrein/kinin system.
Behçet's syndrome and factor XII deficiency.
Cardiopulmonary Bypass in a Patient with Factor XII Deficiency.
Cationic zinc is required for factor XII recruitment and activation by stimulated platelets and for thrombus formation in vivo.
Clinical importance of prothrombotic risk factors in pediatric patients with malignancy--impact of central venous lines.
Coagulation factor XII in thrombosis and inflammation.
Concomitant ST-elevation myocardial infarction and deep vein thrombosis in a patient with severe factor XII deficiency: case report and review of the literature.
Contact activation of blood coagulation on a defined kaolin/collagen surface in a microfluidic assay.
Contradictory functions of sulfatide in the blood coagulation system as coagulant and anticoagulant.
COU254, a specific 3-carboxamide-coumarin inhibitor of coagulation factor XII, does not protect mice from acute ischemic stroke.
CpaA Is a Glycan-Specific Adamalysin-like Protease Secreted by Acinetobacter baumannii That Inactivates Coagulation Factor XII.
Cyclic peptide FXII inhibitor provides safe anticoagulation in a thrombosis model and in artificial lungs.
Deep venous thrombosis and previous myocardial infarction in mild factor XII deficiency: a risk factor for both venous and arterial thrombosis.
Defective thrombus formation in mice lacking coagulation factor XII.
Development of Coagulation Factor XII Antibodies for Inhibiting Vascular Device-Related Thrombosis.
Deviations in coagulation activation due to treatment with different haemodialysis membranes.
Differential binding of factor XII and activated factor XII to soluble and immobilized fibronectin--localization of the Hep-1/Fib-1 binding site for activated factor XII.
Dual inhibition of factor XIIa and factor XIa as a therapeutic approach for safe thromboprotection.
Dual role of collagen in factor XII-dependent thrombus formation.
Emerging anticoagulant strategies.
Evidence of a U-shaped association between factor XII activity and overall survival.
Expression and purification of recombinant serine protease domain of human coagulation factor XII in Pichia pastoris.
Factor XI and factor XII as targets for new anticoagulants.
Factor XII - What's important but not commonly thought about.
Factor XII as a Risk Marker for Hemorrhagic Stroke: A Prospective Cohort Study.
Factor XII as a Therapeutic Target in Thromboembolic and Inflammatory Diseases.
Factor XII assay with the chromogenic substrate chromozym PK.
Factor XII autoantibodies as a novel marker for thrombosis and adverse obstetric history in patients with systemic lupus erythematosus.
Factor XII deficiency associated with coronary stent thrombosis.
Factor XII gene (F12) -4C/C polymorphism in combination with low protein S activity is associated with deep vein thrombosis.
Factor XII in Hemostasis and Thrombosis: Active Player or (Innocent) Bystander?
Factor XII inhibition reduces thrombus formation in a primate thrombosis model.
Factor XII regulates the pathological process of thrombus formation on ruptured plaques.
Factor XII(a) inhibitors: a review of the patent literature.
Factor XII: a drug target for safe interference with thrombosis and inflammation.
Factor XII: a novel target for safe prevention of thrombosis and inflammation.
Factor XII: what does it contribute to our understanding of the physiology and pathophysiology of hemostasis & thrombosis.
Factor XIIa as a Novel Target for Thrombosis: Target Engagement Requirement and Efficacy in a Rabbit Model of Microembolic Signals.
Factor XIIa inhibition by Infestin-4: in vitro mode of action and in vivo antithrombotic benefit.
Factor XIIa inhibitor recombinant human albumin Infestin-4 abolishes occlusive arterial thrombus formation without affecting bleeding.
Factor XIIa regulates the structure of the fibrin clot independently of thrombin generation through direct interaction with fibrin.
Fibrin formation, fibrinopeptide A release, and platelet thrombus dimensions on subendothelium exposed to flowing native blood: greater in factor XII and XI than in factor VIII and IX deficiency.
FXIa and platelet polyphosphate as therapeutic targets during human blood clotting on collagen/tissue factor surfaces under flow.
FXIIa inhibitor rHA-Infestin-4: Safe thromboprotection in experimental venous, arterial and foreign surface-induced thrombosis.
G Protein-Coupled Kinin Receptors and Immunity Against Pathogens.
Generation of a humanized FXII knock-in mouse-A powerful model system to test novel anti-thrombotic agents.
Global cerebral infarction after aortic arch replacement surgery in a patient with postoperatively revealed factor XII deficiency: a case report.
Heestermans M, Salloum-Asfar S, Salvatori D, Laghmani EH, Luken BM, Zeerleder SS, Spronk HMH, Korporaal SJ, Wagenaar GTM, Reitsma PH, van Vlijmen BJM. Role of platelets, neutrophils, and factor XII in spontaneous venous thrombosis in mice. Blood. 2016;127(21):2630-2637.
Hemostasis: old system, new players, new directions.
High-Throughput Docking and Molecular Dynamics Simulations towards the Identification of Potential Inhibitors against Human Coagulation Factor XIIa.
Histidine-rich glycoprotein binds factor XIIa with high affinity and inhibits contact-initiated coagulation.
Huge left atrial thrombus with mitral stenosis in congenital factor XII deficiency.
Human factor XII binding to the glycoprotein Ib-IX-V complex inhibits thrombin-induced platelet aggregation.
Hydrophilic hybrid IPNs of segmented polyurethanes and copolymers of vinylpyrrolidone for applications in medicine.
Identifying novel factor XIIa inhibitors with PCA-GA-SVM developed vHTS models.
In vivo thrombus formation in murine models.
Independent ischemic stroke risk factors in older Americans: a systematic review.
Inhibition of factor XIIa, a new approach in management of thrombosis.
Integrating platelet and coagulation activation in fibrin clot formation.
Intrinsic pathway of coagulation and arterial thrombosis.
Intrinsic Pathway of Coagulation and Thrombosis.
John Hageman's factor and deep-vein thrombosis: Leiden thrombophilia Study.
Knockdown of liver-derived factor XII by GalNAc-siRNA ALN-F12 prevents thrombosis in mice without impacting hemostatic function.
Markers of thromboembolization in a bovine ex vivo left ventricular assist device model.
Molecular mechanisms of thrombus formation in ischemic stroke: novel insights and targets for treatment.
Mouse venous thrombosis upon silencing of anticoagulants depends on tissue factor and platelets, not FXII or neutrophils.
Neutralizing blood-borne polyphosphate in vivo provides safe thromboprotection.
New agents for thromboprotection. A role for factor XII and XIIa inhibition.
New Infestin-4 Mutants with Increased Selectivity against Factor XIIa.
Next-generation antithrombotics in ischemic stroke: preclinical perspective on 'bleeding-free antithrombosis'
Novel anti-thrombotic mechanisms mediated by Mas receptor as result of balanced activities between the kallikrein/kinin and the renin-angiotensin systems.
Paradoxical thrombosis part 1: factor replacement therapy, inherited clotting factor deficiencies and prolonged APTT.
Pathophysiology of thrombophilic states.
Peptide Macrocycle Inhibitor of Coagulation Factor XII with Subnanomolar Affinity and High Target Selectivity.
Pharmacological regulation of factor XII activation may be a new target to control pathological coagulation.
Physiologic activities of the contact activation system.
Plasma Kallikrein Structure Reveals Apple Domain Disc Rotated Conformation Compared to Factor XI.
Platelet polyphosphates: The nexus of primary and secondary hemostasis.
Platelet Surface-Associated Activation and Secretion-Mediated Inhibition of Coagulation Factor XII.
Polyphosphate nanoparticles on the platelet surface trigger contact system activation.
Polyphosphate-induced thrombosis in mice is factor XII dependent and is attenuated by histidine-rich glycoprotein.
Rapid detection of the 46C --> T polymorphism in the factor XII gene, a novel genetic risk factor for thrombosis, by melting peak analysis using fluorescence hybridization probes.
Recurrent thrombosis in a patient with factor XII deficiency.
Relationship between Factor XII deficiency and thrombosis: the debate is still open?
Relationship between factor XII, von Willebrand factor and postoperative deep vein thrombosis.
Role of contact system activation in hemodialyzer-induced thrombogenicity.
Role of Factor XII in hemostasis and thrombosis: clinical implications.
Roles of Factor XII in Innate Immunity.
Selective depletion of factor XI or factor XII with antisense oligonucleotides attenuates catheter thrombosis in rabbits.
Selective depletion of plasma prekallikrein or coagulation factor XII inhibits thrombosis in mice without increased risk of bleeding.
Specific types of activated Factor XII increase following thrombolytic therapy with tenecteplase.
Stearic acid, clotting, and thrombosis.
Substrate-Guided Design of Selective FXIIa Inhibitors Based on the Plant-Derived Momordica cochinchinensis Trypsin Inhibitor-II (MCoTI-II) Scaffold.
Sulfatide can markedly enhance thrombogenesis in rat deep vein thrombosis model.
Synthesis, evaluation and structure-activity relationship of new 3-carboxamide coumarins as FXIIa inhibitors.
Targeting Coagulation Factor XII as a Novel Therapeutic Option in Brain Trauma.
Targeting coagulation factor XII provides protection from pathological thrombosis in cerebral ischemia without interfering with hemostasis.
The Alzheimer's disease peptide A? promotes thrombin generation through activation of coagulation factor XII.
The contact system in liver injury.
The factor XII -4C>T variant and risk of common thrombotic disorders: A HuGE review and meta-analysis of evidence from observational studies.
The factor XIIa blocking antibody 3F7: a safe anticoagulant with anti-inflammatory activities.
The Intrinsic Pathway of Coagulation as a Target for Antithrombotic Therapy.
The plasma contact system, a protease cascade at the nexus of inflammation, coagulation and immunity.
The polyphosphate-factor XII pathway drives coagulation in prostate cancer-associated thrombosis.
The polyphosphate/factor XII pathway in cancer-associated thrombosis: novel perspectives for safe anticoagulation in patients with malignancies.
The rebirth of the contact pathway: a new therapeutic target.
The role of the contact pathway in thrombus propagation.
The Safety and Efficacy of Novel Agents Targeting Factors XI and XII in Early Phase Human Trials.
Thromboembolic diseases in neonates and children.
Thromboembolism in Hageman trait.
Thrombosis in patients with heterozygous and homozygous factor XII deficiency is not explained by the associated presence of factor V Leiden.
Thrombosis in subjects with homozygous and heterozygous factor XII deficiency.
Thrombus formation on transcatheter ASD occluder device in a patient with coagulation factor XII deficiency.
Tissue factor-positive neutrophils bind to injured endothelial wall and initiate thrombus formation.
[Acute ischemic stroke : New approaches to antithrombotic treatment.]
[Congenital deficiency of factor Xii and spontaenous venous thrombosis treated with urokinase]
[Genetic polymorphism and risk of thromboses]
[Hemocoagulation - New views on the old cascade].
[Hereditary deficiency of antithrombin III, protein C, protein S and factor XII in 121 patients with venous or arterial thrombosis]
[Moderate deficiency of Factor XII associated with postoperative deep venous thrombosis]
[New principles in the prognosis, diagnosis, prevention and treatment of the DIC syndrome]
[Superior vena cava thrombosis in a case with low serum factor XII].
Transfusion Reaction
Participation of Hageman factor dependent pathways in human disease states.
Typhoid Fever
Participation of Hageman factor dependent pathways in human disease states.
Urticaria
Factor XII deficiency in a man with gout and angioimmunoblastic lymphadenopathy.
Varicose Veins
Endovenous Thermal Ablation for a Varicose Vein Patient with Factor XII Deficiency: A Case Report.
Vascular System Injuries
Activated factor 12 (FXIIa) predicts recurrent coronary events after an acute myocardial infarction.
The contact system in liver injury.
Venous Thromboembolism
Coagulation factors IX through XIII and the risk of future venous thrombosis: the Longitudinal Investigation of Thromboembolism Etiology.
High factor VIII activity, high plasminogen activator inhibitor 1 antigen levels and low factor XII activity contribute to a thrombophilic tendency in elderly venous thromboembolism patients.
The prevalence of moderate and severe FXII (Hageman factor) deficiency among the normal population: evaluation of the incidence of FXII deficiency among 300 healthy blood donors.
Venous Thrombosis
A comparison of the effects of factor XII deficiency and prekallikrein deficiency on thrombus formation.
An algal sulfated galactan has an unusual dual effect on venous thrombosis due to activation of factor XII and inhibition of the coagulation proteases.
An automated chromogenic peptide substrate assay for coagulation factor XII.
Arterial and venous thrombosis and normal response to streptokinase treatment in a young patient with severe Hageman factor deficiency.
Association of factor XII gene C46T polymorphism with cerebral venous thrombosis in the south Indian population.
Combined severe factor XII deficiency and homozygous factor V Leiden mutation in a patient with venous thrombosis.
Concomitant ST-elevation myocardial infarction and deep vein thrombosis in a patient with severe factor XII deficiency: case report and review of the literature.
Deep venous thrombosis and previous myocardial infarction in mild factor XII deficiency: a risk factor for both venous and arterial thrombosis.
Deep venous thrombosis, protein S deficiency and homozygous Factor XII 46T mutation.
Endovenous Thermal Ablation for a Varicose Vein Patient with Factor XII Deficiency: A Case Report.
Factor XII assay with the chromogenic substrate chromozym PK.
Factor XII C46T gene polymorphism and the risk of cerebral venous thrombosis.
Factor XII gene (F12) -4C/C polymorphism in combination with low protein S activity is associated with deep vein thrombosis.
Heestermans M, Salloum-Asfar S, Salvatori D, Laghmani EH, Luken BM, Zeerleder SS, Spronk HMH, Korporaal SJ, Wagenaar GTM, Reitsma PH, van Vlijmen BJM. Role of platelets, neutrophils, and factor XII in spontaneous venous thrombosis in mice. Blood. 2016;127(21):2630-2637.
John Hageman's factor and deep-vein thrombosis: Leiden thrombophilia Study.
Major and potential prothrombotic genotypes in patients with venous thrombosis and in healthy subjects from Slovenia.
Mouse venous thrombosis upon silencing of anticoagulants depends on tissue factor and platelets, not FXII or neutrophils.
Plasma levels of factor XII, prekallikrein and high molecular weight kininogen in normal blood donors and patients having suffered venous thrombosis.
Platelet polyphosphates: The nexus of primary and secondary hemostasis.
Rebuttal: factor XII levels, factor XII 46 C>T polymorphism and venous thrombosis: a word of caution is needed.
Recurrent thrombosis in a patient with factor XII deficiency.
Relationship between factor XII, von Willebrand factor and postoperative deep vein thrombosis.
Retinal venous thrombosis in a young patient with coagulation factor xii deficiency.
Role of platelets, neutrophils, and factor XII in spontaneous venous thrombosis in mice.
The 46C-->T polymorphism in the factor XII gene (F12) and the risk of venous thrombosis.
The functional -4C>T polymorphism of the coagulation factor XII gene is not associated with deep venous thrombosis.
The occasional venous thromboses seen in patients with severe (homozygous) FXII deficiency are probably due to associated risk factors: a study of prevalence in 21 patients and review of the literature.
The prevalence of factor XII deficiency in 103 orally anticoagulated outpatients suffering from recurrent venous and/or arterial thromboembolism.
Use of "C9/11 Mismatch" Control siRNA Reveals Sequence-Related Off-Target Effect on Coagulation of an siRNA Targeting Mouse Coagulation Factor XII.
[Congenital deficiency of factor Xii and spontaenous venous thrombosis treated with urokinase]
[Deep venous thrombosis of the arm revealing a congenital Factor XII deficiency]
[Factor XII (Hageman factor) deficiency: a risk factor for development of thromboembolism. Incidence of factor XII deficiency in patients after recurrent venous or arterial thromboembolism and myocardial infarction]
[Moderate deficiency of Factor XII associated with postoperative deep venous thrombosis]
[Recurrent venous thromboses in hypoplasia of the vena cava inferior and factor XII deficiency]
Vision Disorders
Cerebral visual impairment and intellectual disability caused by PGAP1 variants.
von Willebrand Disease, Type 1
[Review of patients studied for coagulopathy in a Hematology/Oncology unit].
von Willebrand Diseases
Abnormal proteolytic degradation of von Willebrand factor after desmopressin infusion in a new subtype of von Willebrand disease (ID).
Combination of von Willebrand disease type 1 and partial factor XII deficiency in children: clinical evidence for a diminished bleeding tendency.
Combined von Willebrand disease and Hageman factor deficiency.
Combined von Willebrand's disease and factor XII deficiency in a carrier of haemophilia B.
Factor XII deficiency and von Willebrand's disease in a family of miniature poodle dogs.
Occurrence of coagulation factor deficiency in post-tonsillectomy hemorrhage.
Paradoxical thrombosis part 1: factor replacement therapy, inherited clotting factor deficiencies and prolonged APTT.
Perioperative use of the Thrombelastograph in patients with inherited bleeding disorders.
Preoperative screening for coagulopathy using prothrombin time and partial thromboplastin time in patients requiring primary cranial vault remodeling.
Reaction of blood with artificial surfaces of hemodialyzers. Studies of human blood with platelet defects or coagulation factor deficiencies.
Von Willebrand disease San Diego, a new variant.
[Infective morbidity of replacement therapy in congenital coagulation deficiencies and its effects on demand of coagulation factors]
[Review of patients studied for coagulopathy in a Hematology/Oncology unit].
[Successes and failures of the activated partial thromboplastin time in the preoperative evaluation]
[Unsuspected prolonged activated partial thromboplastin time in emergency surgery. Diagnostic and therapeutic guide]
Wound Infection
Hageman factor dependent activation and its relationship to lethal Pseudomonas aeruginosa burn wound infections.