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Information on EC 3.4.21.35 - tissue kallikrein and Organism(s) Mastomys natalensis and UniProt Accession P32824

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EC Tree
     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.35 tissue kallikrein
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This record set is specific for:
Mastomys natalensis
UNIPROT: P32824 not found.
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Word Map
The taxonomic range for the selected organisms is: Mastomys natalensis
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Reaction Schemes
Preferential cleavage of Arg-/- bonds in small molecule substrates. Highly selective action to release kallidin (lysyl-bradykinin) from kininogen involves hydrolysis of Met-/- or Leu-/-. The rat enzyme is unusual in liberating bradykinin directly from autologous kininogens by cleavage at two Arg-/- bonds
Synonyms
prostate specific antigen, tissue kallikrein, glandular kallikrein, renal kallikrein, trypsin-like serine protease, prokallikrein, klk15, salivary kallikrein, glandular kallikrein 2, urinary kallidinogenase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
bradykininogenase
-
-
-
-
callicrein
-
-
-
-
depot-Padutin
-
-
-
-
dilminal D
-
-
-
-
glandular kallikrein
-
-
-
-
glumorin
-
-
-
-
kallidinogenase
-
-
-
-
kallikrein
-
-
-
-
kallikrein 1
-
-
-
-
kidney/pancreas/salivary gland kallikrein
-
-
-
-
kininogenase
-
-
-
-
kininogenin
-
-
-
-
KLK-S3
-
-
-
-
onokrein P.
-
-
-
-
P1 kallikrein
-
-
-
-
padreatin
-
-
-
-
padutin
-
-
-
-
pancreatic kallikrein
-
-
-
-
PPK
-
-
-
-
Prk
-
-
-
-
PS kallikrein
-
-
-
-
renal tissue kallikrein
-
-
-
-
RSGK-50
-
-
-
-
RUK
-
-
-
-
S01.160
-
-
-
-
S1 kallikrein
-
-
-
-
S2 kallikrein
-
-
-
-
S3 kallikrein
-
-
-
-
salivary kallikrein
-
-
-
-
SEV
-
-
-
-
submandibular enzymatic vasoconstrictor
-
-
-
-
T-kininogenase
-
-
-
-
urinary kallikrein
-
-
-
-
urokallikrein
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
hydrolysis of peptide bond
-
-
-
-
CAS REGISTRY NUMBER
COMMENTARY hide
389069-73-2
-
9001-01-8
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
KLKR_MASNA
263
0
29130
Swiss-Prot
Secretory Pathway (Reliability: 1)
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Boeckmann, B.; Bairoch, A.; Apweiler, R.; Blatter, M.C.; Estreicher, A.; Gasteiger, E.; Martin M.J.; Michoud, K.; O'Donovan, C.; Phan, I.; Pilbout, S.; Schneider, M.
The SWISS-PROT protein knowledgebase and its supplement TrEMBL
Nucleic Acids Res.
31
365-370
2003
Homo sapiens (P06870), Macaca fascicularis (Q07276), Mastomys natalensis (P32824), Mus musculus (P00755), Papio hamadryas (Q28773), Rattus norvegicus (P00758)
Manually annotated by BRENDA team