Reference on EC 3.4.21.34 - plasma kallikrein
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Van der Graaf, F.; Tans, G.; Bouma, B.N.; Griffin, J.H.
Isolation and functional properties of the heavy and light chains of human plasma kallikrein
J. Biol. Chem.
257
14300-14305
1982
Homo sapiens
Heber, H.; Geiger, R.; Heimburger, N.
Human plasma kallikrein: Purification, enzyme characterization and quantitative determination in plasma
Hoppe-Seyler's Z. Physiol. Chem.
359
659-669
1978
Homo sapiens
Colman, R.W.; Bagdasarian, A.
Human kallikrein and prekallikrein
Methods Enzymol.
45
303-322
1976
Bos taurus, Homo sapiens
Sampaio, C.; Wong, S.C.; Shaw, E.
Human plasma kallikrein
Arch. Biochem. Biophys.
165
133-139
1974
Homo sapiens
Mashiko, H.; Kato, K.; Fujii, K.I.; Takahashi, H.
Studies on factor XII in porcine plasma: purification and its conversion to activated form by porcine plasma kallikrein
Biochim. Biophys. Acta
1296
198-206
1996
Sus scrofa
Evans, D.M.; Jones, D.M.; Pitt, G.R.; Suerias-Diaz, J.; Horton, J.; Ashworth, D.; Olsson, H.; Szelke, M.
Selective inhibitors of plasma kallikrein
Immunopharmacology
32
115-116
1996
Homo sapiens
Oliva, M.L.V.; Andrade, S.; Batista, I.F.C.; Sampaio, M.U.; Juliano, M.; Fritz, H.; Auerswald, E.A.; Sampaio, C.A.M.
Human plasma kallikrein and tissue kallikrein binding to a substrate based on the reactive site of a factor Xa inhibitor isolates from Bauhinia ungulata seeds
Immunopharmacology
45
145-149
1999
Homo sapiens, Sus scrofa
Diniz, M.R.V.; Oliveira, E.B.
Purification and properties of a kininogenin from the venom of Lachesis muta (bushmaster)
Toxicon
30
247-258
1992
Lachesis muta
Tada, M.; Wanaka, K.; Okamoto, S.; Okamoto, U.; Nakaya, Y.; Horie, N.; Hijkata-Okunomiya, A.; Tsuda, Y.; Okada, Y.
Purification method for human plasma kallikrein by a new affinity chromatography
Biol. Pharm. Bull.
21
105-108
1998
Homo sapiens
Seidah, N.G.; Sawyer, N.; Hamelin, J.; Mion, P.; Beaubien, G.; Brachpapa, L.; Rochemont, J.; Mbikay, M.; Chretien, M.
Mouse plasma kallikrein: cDNA structure, enzyme characterization, and comparison of protein and mRNA levels among species
DNA Cell Biol.
9
737-748
1990
Mus musculus
Paquin, J.; Benjannet, S.; Sawyer, N.; Lazure, C.; Chretien, M.; Seidah, N.G.
Rat plasma kallikrein: purification, NH2-terminal sequencing and development of a specific radioimmunoassay
Biochim. Biophys. Acta
999
103-110
1989
Rattus norvegicus
Heimark, R.L.; Davie, E.W.
Bovine and human plasma prekallikrein
Methods Enzymol.
80
157-173
1981
Bos taurus, Homo sapiens
Naess, F.; Roeise, O.; Johansen, H.T.; Stadaas, J.O.; Aasen, A.O.
Hemodynamic and proteolytic effects of intravenous injection of purified human plasma kallikrein
Am. J. Physiol.
263
405-409
1992
Homo sapiens
-
Boeckmann, B.; Bairoch, A.; Apweiler, R.; Blatter, M.C.; Estreicher, A.; Gasteiger, E.; Martin M.J.; Michoud, K.; O'Donovan, C.; Phan, I.; Pilbout, S.; Schneider, M.
The SWISS-PROT protein knowledgebase and its supplement TrEMBL
Nucleic Acids Res.
31
365-370
2003
Homo sapiens (P03952), Rattus norvegicus (P14272), Mus musculus (P26262)
Cavalcanti, M.d.S.M.; Oliva, M.L.V.; Fritz, H.; Jochum, M.; Mentele, R.; Sampaio, M.; Coelho, L.C.B.B.; Batista, I.F.C.; Sampaio, C.A.M.
Characterization of a Kunitz trypsin inhibitor with one disulfide bridge purified from Swartzia pickellii
Biochem. Biophys. Res. Commun.
291
635-639
2002
Homo sapiens
Parthasarathy, N.; Torti, S.V.; Torti, F.M.
Ferritin binds to light chain of human H-kininogen and inhibits kallikrein-mediated bradykinin release
Biochem. J.
365
279-286
2002
Homo sapiens
Almeida, P.C.; Chagas, J.R.; Cezari, M.H.; Juliano, M.A.; Juliano, L.
Hydrolysis by plasma kallikrein of fluorogenic peptides derived from prorenin processing site
Biochim. Biophys. Acta
1479
83-90
2000
Homo sapiens, Rattus norvegicus
Oliva, M.L.; Santomauro-Vaz, E.M.; Andrade, S.A.; Juliano, M.A.; Pott, V.J.; Sampaio, M.U.; Sampaio, C.A.
Synthetic peptides and fluorogenic substrates related to the reactive site sequence of Kunitz-type inhibitors isolated from Bauhinia: interaction with human plasma kallikrein
Biol. Chem.
382
109-113
2001
Homo sapiens
Dulinski, R.; Suder, P.; Guevara-Lora, I.; Rapala-Kozik, M.; Potempa, J.; Silberring, J.; Imamura, T.; Travis, J.; Kozik, A.
Attenuated kinin release from human neutrophil elastase-pretreated kininogens by tissue and plasma kallikreins
Biol. Chem.
384
929-937
2003
Homo sapiens
Tada, M.; Tsuda, Y.; Wanaka, K.; Hijikata-Okunomiya, A.; Horie, N.; Okamoto, U.; Okamoto, S.; Okada, Y.
Isolation of plasma kallikrein by high efficiency affinity chromatography and its characterization
Biol. Pharm. Bull.
24
520-524
2001
Homo sapiens
Fukumizu, A.; Tsuda, Y.; Wanaka, K.; Tada, M.; Okamoto, S.; Hijikata-Okunomiya, A.; Okada, Y.
Amino acids and peptides. LIII. Synthesis and biological activities of some pseudo-peptide analogs of PKSI-527, a plasma kallikrein selective inhibitor: the importance of the peptide backbone
Chem. Pharm. Bull.
47
1141-1144
1999
Homo sapiens
Okada, Y.; Tsuda, Y.; Tada, M.; Wanaka, K.; Okamoto, U.; Hijikata-Okunomiya, A.; Okamoto, S.
Development of potent and selective plasmin and plasma kallikrein inhibitors and studies on the structure-activity relationship
Chem. Pharm. Bull.
48
1964-1972
2000
Homo sapiens
Oliva, M.L.; Mendes, C.R.; Santomauro-Vaz, E.M.; Juliano, M.A.; Mentele, R.; Auerswald, E.A.; Sampaio, M.U.; Sampaio, C.A.
Bauhinia bauhinioides plasma kallikrein inhibitor: interaction with synthetic peptides and fluorogenic peptide substrates related to the reactive site sequence
Curr. Med. Chem.
8
977-984
2001
Homo sapiens
Rojkjaer, R.; Schmaier, A.H.
Activation of the plasma kallikrein/kinin system on endothelial cell membranes
Immunopharmacology
43
109-114
1999
Homo sapiens
Hayashi, J.; Salomon, D.R.; Hugli, T.E.
Elevated kallikrein activity in plasma from stable liver transplant recipients
Int. Immunopharmacol.
2
1667-1680
2002
Homo sapiens
Gozzo, A.J.; Nunes, V.A.; Carmona, A.K.; Nader, H.B.; von Dietrich, C.P.; Silveira, V.L.; Shimamoto, K.; Ura, N.; Sampaio, M.U.; Sampaio, C.A.; Araujo, M.S.
Glycosaminoglycans affect the action of human plasma kallikrein on kininogen hydrolysis and inflammation
Int. Immunopharmacol.
2
1861-1865
2002
Homo sapiens
Peek, M.; Moran, P.; Mendoza, N.; Wickramasinghe, D.; Kirchhofer, D.
Unusual proteolytic activation of pro-hepatocyte growth factor by plasma kallikrein and coagulation factor XIa
J. Biol. Chem.
277
47804-47809
2002
Homo sapiens
Kirchhofer, D.; Peek, M.; Li, W.; Stamos, J.; Eigenbrot, C.; Kadkhodayan, S.; Elliott, J.M.; Corpuz, R.T.; Lazarus, R.A.; Moran, P.
Tissue expression, protease specificity, and Kunitz domain functions of hepatocyte growth factor activator inhibitor-1B (HAI-1B), a new splice variant of HAI-1
J. Biol. Chem.
278
36341-36349
2003
Homo sapiens
Cerf, M.E.; Raidoo, D.M.
Immunolocalization of plasma kallikrein in human brain
Metab. Brain Dis.
15
315-323
2000
Homo sapiens
Cocude, C.; Pierrot, C.; Cetre, C.; Fontaine, J.; Godin, C.; Capron, A.; Khalife, J.
Identification of a developmentally regulated Schistosoma mansoni serine protease homologous to mouse plasma kallikrein and human factor I
Parasitology
118
389-396
1999
Schistosoma mansoni (Q9TYH4)
-
Sulikowski, T.; Bauer, B.A.; Patston, P.A.
alpha1-Proteinase inhibitor mutants with specificity for plasma kallikrein and C1s but not C1
Protein Sci.
11
2230-2236
2002
Homo sapiens
Briseid, K.; Johannesen, S.
Part of purified human plasma kallikrein removed together with a remaining IgG fraction - immunoblot experiments and functional tests
Scand. J. Clin. Lab. Invest.
62
21-24
2002
Homo sapiens
Shariat-Madar, Z.; Rahimy, E.; Mahdi, F.; Schmaier, A.H.
Overexpression of prolylcarboxypeptidase enhances plasma prekallikrein activation on Chinese hamster ovary cells
Am. J. Physiol. Heart Circ. Physiol.
289
H2697-H2703
2005
Cricetulus griseus
Barros, N.M.; Puzer, L.; Tersariol, I.L.; Oliva, M.L.; Sampaio, C.A.; Carmona, A.K.; da Motta, G.
Plasma prekallikrein/kallikrein processing by lysosomal cysteine proteases
Biol. Chem.
385
1087-1091
2004
Homo sapiens
Neth, P.; Arnhold, M.; Sidarovich, V.; Bhoola, K.D.; Fink, E.
Expression of the plasma prekallikrein gene: utilization of multiple transcription start sites and alternative promoter regions
Biol. Chem.
386
101-109
2005
Homo sapiens, Rattus norvegicus
Vonnahme, K.A.; Fernando, S.C.; Ross, J.W.; Ashworth, M.D.; DeSilva, U.; Malayer, J.R.; Geisert, R.D.
Porcine endometrial expression of kininogen, factor XII, and plasma kallikrein in cyclic and pregnant gilts
Biol. Reprod.
70
132-138
2004
Sus scrofa
Young, W.B.; Rai, R.; Shrader, W.D.; Burgess-Henry, J.; Hu, H.; Elrod, K.C.; Sprengeler, P.A.; Katz, B.A.; Sukbuntherng, J.; Mordenti, J.
Small molecule inhibitors of plasma kallikrein
Bioorg. Med. Chem. Lett.
16
2034-2036
2006
Rattus norvegicus
Rosatelli, T.B.; Roselino, A.M.; Dellalibera-Joviliano, R.; Reis, M.L.; Donadi, E.A.
Increased activity of plasma and tissue kallikreins, plasma kininase II and salivary kallikrein in pemphigus foliaceus (fogo selvagem)
Br. J. Dermatol.
152
650-657
2005
Homo sapiens
Tang, J.; Yu, C.L.; Williams, S.R.; Springman, E.; Jeffery, D.; Sprengeler, P.A.; Estevez, A.; Sampang, J.; Shrader, W.; Spencer, J.; Young, W.; McGrath, M.; Katz, B.A.
Expression, crystallization, and three-dimensional structure of the catalytic domain of human plasma kallikrein
J. Biol. Chem.
280
41077-41089
2005
Homo sapiens (Q92876), Homo sapiens
Shariat-Madar, Z.; Schmaier, A.H.
The plasma kallikrein/kinin and renin angiotensin systems in blood pressure regulation in sepsis
J. Endotoxin Res.
10
3-13
2004
Homo sapiens
Storini, C.; Bergamaschini, L.; Gesuete, R.; Rossi, E.; Maiocchi, D.; De Simoni, M.G.
Selective inhibition of plasma kallikrein protects brain from reperfusion injury
J. Pharmacol. Exp. Ther.
318
849-854
2006
Mus musculus
Ravindran, S.; Grys, T.E.; Welch, R.A.; Schapira, M.; Patston, P.A.
Inhibition of plasma kallikrein by C1-inhibitor: role of endothelial cells and the amino-terminal domain of C1-inhibitor
Thromb. Haemost.
92
1277-1283
2004
Homo sapiens
Gozzo, A.J.; Nunes, V.A.; Cruz-Silva, I.; Carmona, A.K.; Nader, H.B.; Faljoni-Alario, A.; Sampaio, M.U.; Araujo, M.S.
Heparin modulation of human plasma kallikrein on different substrates and inhibitors
Biol. Chem.
387
1129-1138
2006
Homo sapiens
Fink, E.; Bhoola, K.D.; Snyman, C.; Neth, P.; Figueroa, C.D.
Cellular expression of plasma prekallikrein in human tissues
Biol. Chem.
388
957-963
2007
Homo sapiens (P03952), Homo sapiens
Isawa, H.; Orito, Y.; Jingushi, N.; Iwanaga, S.; Morita, A.; Chinzei, Y.; Yuda, M.
Identification and characterization of plasma kallikrein-kinin system inhibitors from salivary glands of the blood-sucking insect Triatoma infestans
FEBS J.
274
4271-4286
2007
Homo sapiens
Schmaier, A.H.
Assembly, activation, and physiologic influence of the plasma kallikrein/kinin system
Int. Immunopharmacol.
8
161-165
2008
Homo sapiens
Govers-Riemslag, J.W.; Smid, M.; Cooper, J.A.; Bauer, K.A.; Rosenberg, R.D.; Hack, C.E.; Hamulyak, K.; Spronk, H.M.; Miller, G.J.; ten Cate, H.
The plasma kallikrein-kinin system and risk of cardiovascular disease in men
J. Thromb. Haemost.
5
1896-1903
2007
Homo sapiens
Sainz, I.M.; Pixley, R.A.; Colman, R.W.
Fifty years of research on the plasma kallikrein-kinin system: from protein structure and function to cell biology and in-vivo pathophysiology
Thromb. Haemost.
98
77-83
2007
Homo sapiens
Saito, A.
Plasma kallikrein is activated on dermatan sulfate and cleaves factor H
Biochem. Biophys. Res. Commun.
370
646-650
2008
Homo sapiens
Lima, A.R.; Alves, F.M.; Angelo, P.F.; Andrade, D.; Blaber, S.I.; Blaber, M.; Juliano, L.; Juliano, M.A.
S(1) and S(2) subsite specificities of human plasma kallikrein and tissue kallikrein 1 for the hydrolysis of peptides derived from the bradykinin domain of human kininogen
Biol. Chem.
389
1487-1494
2008
Homo sapiens
Planque, C.; Li, L.; Zheng, Y.; Soosaipillai, A.; Reckamp, K.; Chia, D.; Diamandis, E.P.; Goodglick, L.
A multiparametric serum kallikrein panel for diagnosis of non-small cell lung carcinoma
Clin. Cancer Res.
14
1355-1362
2008
Homo sapiens
Lehmann, A.
Ecallantide (DX-88), a plasma kallikrein inhibitor for the treatment of hereditary angioedema and the prevention of blood loss in on-pump cardiothoracic surgery
Expert. Opin. Biol. Ther.
8
1187-1199
2008
Homo sapiens
Phipps, J.A.; Clermont, A.C.; Sinha, S.; Chilcote, T.J.; Bursell, S.E.; Feener, E.P.
Plasma kallikrein mediates angiotensin II type 1 receptor-stimulated retinal vascular permeability
Hypertension
53
175-181
2009
Rattus norvegicus
Lilla, J.N.; Joshi, R.V.; Craik, C.S.; Werb, Z.
Active plasma kallikrein localizes to mast cells and regulates epithelial cell apoptosis, adipocyte differentiation and stromal remodeling during mammary gland involution
J. Biol. Chem.
284
13792-13803
2009
Mus musculus
Sexton, D.J.; Chen, T.; Martik, D.; Kuzmic, P.; Kuang, G.; Chen, J.; Nixon, A.E.; Zuraw, B.L.; Forteza, R.M.; Abraham, W.M.; Wood, C.R.
Specific inhibition of tissue kallikrein 1 with a human monoclonal antibody reveals a potential role in airway diseases
Biochem. J.
422
383-392
2009
Homo sapiens
Stoop, A.A.; Joshi, R.V.; Eggers, C.T.; Craik, C.S.
Analysis of an engineered plasma kallikrein inhibitor and its effect on contact activation
Biol. Chem.
391
425-433
2010
Homo sapiens
Abid, K.; Rochat, B.; Lassahn, P.G.; Stoecklin, R.; Michalet, S.; Brakch, N.; Aubert, J.F.; Vatansever, B.; Tella, P.; De Meester, I.; Grouzmann, E.
Kinetic study of neuropeptide Y (NPY) proteolysis in blood and identification of NPY3-35: a new peptide generated by plasma kallikrein
J. Biol. Chem.
284
24715-24724
2009
Homo sapiens
Pnitz, V.; Govers-Riemslag, J.; Brgger-Andersen, T.; Ten Cate, H.; Nilsen, D.
Inhibitor complexes of the plasma kallikrein-kinin system and outcome prediction in patients following admission for chest pain
J. Thromb. Haemost.
7
1231-1233
2009
Homo sapiens
Almeida, S.S.; Barros, C.C.; Moraes, M.R.; Russo, F.J.; Haro, A.S.; Rosa, T.S.; Alves, M.F.; Pesquero, J.B.; Carmona, A.K.; Bacurau, R.F.; Araujo, R.C.
Plasma Kallikrein and Angiotensin I-converting enzyme N- and C-terminal domain activities are modulated by the insertion/deletion polymorphism
Neuropeptides
44
139-143
2010
Homo sapiens
Earl, S.T.; Richards, R.; Johnson, L.A.; Flight, S.; Anderson, S.; Liao, A.; de Jersey, J.; Masci, P.P.; Lavin, M.F.
Identification and characterisation of Kunitz-type plasma kallikrein inhibitors unique to Oxyuranus sp. snake venoms
Biochimie
94
365-373
2011
Homo sapiens
Vergiliana, J.F.; Asokananthan, N.; Stewart, G.A.
Activation of the plasma kallikrein-kinin system on human lung epithelial cells
Biol. Chem.
391
1067-1077
2010
Homo sapiens
Varano Della Vergiliana, J.F.; Lansley, S.; Tan, A.L.; Creaney, J.; Lee, Y.C.; Stewart, G.A.
Mesothelial cells activate the plasma kallikrein-kinin system during pleural inflammation
Biol. Chem.
392
633-642
2011
Homo sapiens
Yasuda, Y.; Lu, Z.; Kato, N.; Jomori, T.
Change in blood kinin and plasma porcine pancreatic kallikrein concentrations after oral administration of kallikrein formulation in dog
Biol. Pharm. Bull.
34
1518-1521
2011
Sus scrofa
Abdallah, R.T.; Keum, J.S.; El-Shewy, H.M.; Lee, M.H.; Wang, B.; Gooz, M.; Luttrell, D.K.; Luttrell, L.M.; Jaffa, A.A.
Plasma kallikrein promotes epidermal growth factor receptor transactivation and signaling in vascular smooth muscle through direct activation of protease-activated receptors
J. Biol. Chem.
285
35206-35215
2010
Homo sapiens
Liu, J.; Gao, B.B.; Clermont, A.C.; Blair, P.; Chilcote, T.J.; Sinha, S.; Flaumenhaft, R.; Feener, E.P.
Hyperglycemia-induced cerebral hematoma expansion is mediated by plasma kallikrein
Nat. Med.
17
206-210
2011
Rattus norvegicus
Renne, T.
The vascular side of plasma kallikrein
Blood
125
589-590
2015
Mus musculus
Baeriswyl, V.; Rapley, H.; Pollaro, L.; Stace, C.; Teufel, D.; Walker, E.; Chen, S.; Winter, G.; Tite, J.; Heinis, C.
Bicyclic peptides with optimized ring size inhibit human plasma kallikrein and its orthologues while sparing paralogous proteases
ChemMedChem
7
1173-1176
2012
Homo sapiens (P03952), Homo sapiens
Ravindran, S.; Schapira, M.; Patston, P.A.
Modulation of C1-inhibitor and plasma kallikrein activities by type IV collagen
Int. J. Biomater.
2012
212417
2012
Homo sapiens
Kenniston, J.; Faucette, R.; Martik, D.; Comeau, S.; Lindberg, A.; Kopacz, K.; Conley, G.; Chen, J.; Viswanathan, M.; Kastrapeli, N.; Cosic, J.; Mason, S.; DiLeo, M.; Abendroth, J.; Kuzmic, P.; Ladner, R.; Edwards, T.; TenHoor, C.; Adelman, B.; Nixon, A.;
Inhibition of plasma kallikrein by a highly specific active site blocking antibody
J. Biol. Chem.
289
23596-23608
2014
Macaca fascicularis, Mus musculus, Rattus norvegicus, Homo sapiens (P03952), Homo sapiens
Koumandou, V.L.; Scorilas, A.
Evolution of the plasma and tissue kallikreins, and their alternative splicing isoforms
PLoS ONE
8
e68074
2013
Homo sapiens
Veronez, C.L.; Nascimento, F.D.; Melo, K.R.; Nader, H.B.; Tersariol, I.L.; Motta, G.
The involvement of proteoglycans in the human plasma prekallikrein interaction with the cell surface
PLoS ONE
9
e91280
2014
Homo sapiens
Renne, T.; Gruber, A.
Plasma kallikrein: Novel functions for an old protease
Thromb. Haemost.
107
1012-1013
2012
Mus musculus
Bjoerkqvist, J.; Jaemsae, A.; Renne, T.
Plasma kallikrein: the bradykinin-producing enzyme
Thromb. Haemost.
110
399-407
2013
Homo sapiens
Pathak, M.; Wong, S.S.; Dreveny, I.; Emsley, J.
Structure of plasma and tissue kallikreins
Thromb. Haemost.
110
423-433
2013
Homo sapiens (P03952)
Feener, E.P.; Zhou, Q.; Fickweiler, W.
Role of plasma kallikrein in diabetes and metabolism
Thromb. Haemost.
110
434-441
2013
Mus musculus
Ottaiano, T.F.; Andrade, S.S.; de Oliveira, C.; Silva, M.C.C.; Buri, M.V.; Juliano, M.A.; Girao, M.J.B.C.; Sampaio, M.U.; Schmaier, A.H.; Wlodawer, A.; Maffei, F.H.A.; Oliva, M.L.V.
Plasma kallikrein enhances platelet aggregation response by subthreshold doses of ADP
Biochimie
135
72-81
2017
Homo sapiens
Lieb, W.; Chen, M.; Teumer, A.; De Boer, R.; Lin, H.; Fox, E.; Musani, S.; Wilson, J.; Wang, T.; Voelzke, H.; Petersen, A.; Meisinger, C.; Nauck, M.; Schlesinger, S.; Li, Y.; Menard, J.; Hercberg, S.; Wichmann, H.; Voelker, U.; Rawal, R.; Bidlingmaier, M.
Genome-wide meta-analyses of plasma renin activity and concentration reveal association with the kininogen 1 and prekallikrein genes
Circ. Cardiovasc. Genet.
8
131-140
2015
Homo sapiens
Fischer, C.; Lamer, T.; Wang, W.; McKinnie, S.M.K.; Iturrioz, X.; Llorens-Cortes, C.; Oudit, G.Y.; Vederas, J.C.
Plasma kallikrein cleaves and inactivates apelin-17 Palmitoyl- and PEG-extended apelin-17 analogs as metabolically stable blood pressure-lowering agents
Eur. J. Med. Chem.
166
119-124
2019
Homo sapiens
Xu, M.; Chen, Y.; Xu, P.; Andreasen, P.A.; Jiang, L.; Li, J.; Huang, M.
Crystal structure of plasma kallikrein reveals the unusual flexibility of the S1 pocket triggered by Glu217
FEBS Lett.
592
2658-2667
2018
Mus musculus (P26262), Mus musculus
Schmaier, A.H.
Plasma prekallikrein its role in hereditary angioedema and health and disease
Front. Med.
5
3-3
2018
Homo sapiens, Mus musculus
Motta, G.; Tersariol, I.L.S.
Modulation of the plasma kallikrein-kinin system proteins performed by heparan sulfate proteoglycans
Front. Physiol.
8
481
2017
Homo sapiens
Teufel, D.P.; Bennett, G.; Harrison, H.; van Rietschoten, K.; Pavan, S.; Stace, C.; Le Floch, F.; Van Bergen, T.; Vermassen, E.; Barbeaux, P.; Hu, T.T.; Feyen, J.H.M.; Vanhove, M.
Stable and long-lasting, novel bicyclic peptide plasma kallikrein inhibitors for the treatment of diabetic macular edema
J. Med. Chem.
61
2823-2836
2018
Rattus norvegicus
Partridge, J.R.; Choy, R.M.; Silva-Garcia, A.; Yu, C.; Li, Z.; Sham, H.; Metcalf, B.
Structures of full-length plasma kallikrein bound to highly specific inhibitors describe a new mode of targeted inhibition
J. Struct. Biol.
206
170-182
2019
Homo sapiens (P03952)
Li, C.; Voos, K.M.; Pathak, M.; Hall, G.; McCrae, K.R.; Dreveny, I.; Li, R.; Emsley, J.
Plasma kallikrein structure reveals apple domain disc rotated conformation compared to factor XI
J. Thromb. Haemost.
17
759-770
2019
Homo sapiens (P03952), Homo sapiens
Goebel, K.; Asaridou, C.M.; Merker, M.; Eichler, S.; Herrmann, A.M.; Geuss, E.; Ruck, T.; Schuengel, L.; Groeneweg, L.; Narayanan, V.; Schneider-Hohendorf, T.; Gross, C.C.; Wiendl, H.; Kehrel, B.E.; Kleinschnitz, C.; Meuth, S.G.
Plasma kallikrein modulates immune cell trafficking during neuroinflammation via PAR2 and bradykinin release
Proc. Natl. Acad. Sci. USA
116
271-276
2019
Homo sapiens, Mus musculus
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