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Information on EC 3.4.21.1 - chymotrypsin and Organism(s) Solenopsis invicta and UniProt Accession Q7SIG2

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EC Tree
     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.1 chymotrypsin
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This record set is specific for:
Solenopsis invicta
UNIPROT: Q7SIG2 not found.
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Word Map
The taxonomic range for the selected organisms is: Solenopsis invicta
The enzyme appears in selected viruses and cellular organisms
Reaction Schemes
Preferential cleavage: Tyr-/-, Trp-/-, Phe-/-, Leu-/-
Synonyms
chymotrypsin, alpha-chymotrypsin, bovine alpha-chymotrypsin, chymotrypsin a, alpha-ct, chymotrypsin b, chtp, alpha chymotrypsin, alpha-chymotrypsin a, chymotrypsin ii, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
chymotrypsin C1
-
alpha chymar
-
-
-
-
alpha-chymar ophth
-
-
-
-
alpha-chymotrypsin
-
-
-
-
alpha-chymotrypsin A
-
-
-
-
avazyme
-
-
-
-
chymar
-
-
-
-
chymotest
-
-
-
-
chymotrypsin A
-
-
-
-
chymotrypsin B
-
-
-
-
EC 3.4.4.6
-
-
-
-
enzeon
-
-
-
-
quimar
-
-
-
-
quimotrase
-
-
-
-
CAS REGISTRY NUMBER
COMMENTARY hide
9004-07-3
-
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
casein + H2O
fragments of casein
show the reaction diagram
-
-
?
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
Phenylmethylsulfonylfluoride
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
fire ant
Uniprot
Manually annotated by BRENDA team
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
CTR1_SOLIN
222
0
24012
Swiss-Prot
other Location (Reliability: 3)
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
24061
2 * 24061, MALDI mass spectroscopy
48000
chymotrypsin C1 migrates on SDS-PAGE as a very stable dimer of 48000 Da
SUBUNIT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
dimer
2 * 24061, MALDI mass spectroscopy
CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
hanging drop vapor diffusion, diffraction-quality crystals are grown from droplets containing an equal mixture of inhibited protein and precipitant, i.e. 100 mM PIPES, 1.6 M ammonium sulfate, pH 6.5, crystals diffract to 1.7 A
PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Botos, I.; Meyer, E.; Nguyen, M.; Swanson, S.M.; Koomen, J.M.; Russell, D.H.; Meyer, E.F.
The structure of an insect chymotrypsin
J. Mol. Biol.
298
895-901
2000
Solenopsis invicta (Q7SIG2)
Manually annotated by BRENDA team