Reference on EC 3.4.13.9 - Xaa-Pro dipeptidase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Radzicka, A.; Wolfenden, R.
Phosphoenolpyruvate as a natural bisubstrate analogue inhibitor of pig kidney prolidase
J. Am. Chem. Soc.
112
1248-1249
1990
Sus scrofa
-
Endo, F.; Tanoue, A.; Nakai, H.; Hata, A.; Indo, Y.; Titani, K.; Matsuda, I.
Primary structure and gene localization of human prolidase
J. Biol. Chem.
264
4476-4481
1989
Homo sapiens
Myara, I.; Moatti, N.; Lemonnier, A.
Separation of two erythrocyte prolidase isoforms by fast protein liquid chromatography; application to prolidase deficiency
J. Chromatogr.
493
170-175
1989
Homo sapiens
Lacoste, A.M.; Neuzil, E.
Inhibition of kidney prolidase by phosphonic compounds
Biochem. Soc. Trans.
17
782-783
1989
Sus scrofa
-
Richter, A.M.; Lancaster, G.L.; Choy, F.Y.M.; Hechtman, P.
Purification and characterization of activated human erythrocyte prolidase
Biochem. Cell Biol.
67
34-41
1989
Homo sapiens
King, G.F.; Crossley, M.J.; Kuchel, P.W.
Inhibition and active-site modelling of prolidase
Eur. J. Biochem.
180
377-384
1989
Sus scrofa
Lin, L.N.; Brandts, J.F.
Isomer-specific proteolysis of model substrates: influence that the location of the proline residue exerts on cis/trans specificity
Biochemistry
24
6533-6538
1985
Sus scrofa
Butterworth, J.; Priestman, D.A.
Prolidases of human skin fibroblasts
Biochem. Soc. Trans.
13
237
1985
Homo sapiens
-
Kaminogawa, S.; Azuma, N.; Hwang, I.K.; Suzuki, Y.; Yamauchi, K.
Isolation and characterization of a prolidase from Streptococcus cremoris H61
Agric. Biol. Chem.
48
3035-3040
1984
Lactococcus cremoris
-
Sjoestroem, H.; Noren, O.; Josefsson, L.
Purification and specificity of pig intestinal prolidase
Biochim. Biophys. Acta
327
457-470
1973
Sus scrofa
Yoshimoto, T.; Matsubara, F.; Kawano, E.; Tsuru, D.
Prolidase from bovine intestine: purification and characterization
J. Biochem.
94
1889-1896
1983
Bos taurus
Brown, P.; O'Cuinn, G.
The purification and characterization of a proline dipeptidase from guinea pig brain
J. Biol. Chem.
258
6147-6154
1983
Cavia porcellus
Ruttloff, H.; Friese, E.; Lasch, J.; Koelsch, R.
Gewinnung und Charakterisierung von Prolidase aus Escherichia coli B II. Charakterisierung, Reinigung und Traegerfixierung des Enzyms
Acta Biotechnol.
2
161-170
1982
Escherichia coli, Escherichia coli B / ATCC 11303
-
Johnson, G.L.; Brown, J.L.
Partial purification and characterization of two peptidases from Neurospora crassa
Biochim. Biophys. Acta
370
530-540
1974
Neurospora crassa
Sjoestroem, H.; Noren, O.
Structural properties of pig intestinal proline dipeptidase
Biochim. Biophys. Acta
359
177-185
1974
Sus scrofa
Sjoestroem, H.
Enzymatic properties of pig intestinal proline dipeptidase
Acta Chem. Scand. B
28
802-808
1974
Sus scrofa
Baksi, K.; Radhakrishnan, A.N.
Purification and properties of prolidase (imidodipeptidase) from monkey small intestine
Indian J. Biochem. Biophys.
11
7-11
1974
Macaca radiata
Ryden, A.C.
Separation and characterization of three proline peptidases from a strain of Arthrobacter
Acta Chem. Scand.
25
847-858
1971
Arthrobacter sp.
Davis, N.C.; Smith, E.L.
Purification and some properties of prolidase of swine kidney
J. Biol. Chem.
224
261-275
1957
Sus scrofa
Morel, F.; Frot-Coutaz, F.; Aubel, D.; Portalier, R.; Atlan, D.
Characterization of a prolidase from Lactobacillus delbrueckii subsp. bulgaricus CNRZ 397 with an unusual regulation of biosynthesis
Microbiology
145
437-446
1999
Lactobacillus delbrueckii
Fernandez-Espla, M.D.; Martin-Hernandez, M.C.; Fox, P.F.
Purification and characterization of a prolidase from Lactobacillus casei subsp. casei IFPL 731
Appl. Environ. Microbiol.
63
314-316
1997
Lacticaseibacillus casei
Kumaravel, G.; Boettcher, B.R.; Shapiro, M.J.; Petter, R.C.
Peptide mimics of glycylproline as inhibitors of prolidase
Bioorg. Med. Chem. Lett.
5
2825-2828
1995
Sus scrofa
-
Mock, W.L.; Liu, Y.
Inhibition of prolidase by phosphoenolpyruvate is biphasic. Avoidance of endogenous-metabolite inactivation by cooperativity within an enzyme dimer
Bioorg. Med. Chem. Lett.
5
627-630
1995
Sus scrofa
-
Underwood, R.; Chiravuri, M.; Lee, H.; Schmitz, T.; Kabcenell, A.K.; Yardley, K.; Huber, B.T.
Sequence, purification, and cloning of an intracellular serine protease, quiescent cell proline dipeptidase
J. Biol. Chem.
274
34053-34058
1999
Homo sapiens
Myara, I.; Cosson, C.; Moatti, N.; Lemonnier, A.
Human kidney prolidase--purification, preincubation properties and immunological reactivity
Int. J. Biochem.
26
207-214
1994
Homo sapiens
Suga, K.; Kabashima, T.; Ito, K.; Tsuru, D.; Okamura, H.; Kataoka, J.; Yoshimoto, T.
Prolidase from Xanthomonas maltophilia: purification and characterization of the enzyme
Biosci. Biotechnol. Biochem.
59
2087-2090
1995
Stenotrophomonas maltophilia
Fujii, M.; Nagaoka, Y.; Imamura, S.; Shimizu, T.
Purification and characterization of a prolidase from Aureobacterium esteraromaticum
Biosci. Biotechnol. Biochem.
60
1118-1122
1996
Microbacterium esteraromaticum
Stucky, K.; Klein, F.R.; Schueller, A.; Matern, H.; Henrich, B.; Plapp, R.
Cloning and DNA sequence analysis of pepQ, a prolidase gene from Lactobacillus delbrueckii subsp. lactis DSM7290 and partial characterization of its product
Mol. Gen. Genet.
247
494-500
1995
Lactobacillus delbrueckii
Mock, W.L.; Green, P.C.
Mechanism and inhibition of prolidase
J. Biol. Chem.
265
19606-19610
1990
Sus scrofa
Ohhashi, T.; Ohno, t.; Arata, J.; Sugahara, K.; Kodama, H.
Characterization of prolidase I and II from erythrocytes of a control, a patient with prolidase deficiency and her mother
Clin. Chim. Acta
187
1-10
1990
Homo sapiens
Chiravuri, M.; Schmitz, T.; Yardley, K.; Underwood, R.; Dayal, Y.; Huber, B.T.
A novel apoptotic pathway in quiescent lymphocytes identified by inhibition of a post-proline cleaving aminodipeptidase: a candidate target protease, quiescent cell proline dipeptidase
J. Immunol.
163
3092-3099
1999
Homo sapiens
Ghosh, M.; Grunden, A.M.; Dunn, D.M.; Weiss, R.; Adams, M.W.W.
Characterization of native and recombinant forms of an unusual cobalt-dependent proline dipeptidase (prolidase) from the hyperthermophilic archaeon Pyrococcus furiosus
J. Bacteriol.
180
4781-4789
1998
Pyrococcus furiosus
Masuda, S.; Watanabe, H.; Morioka, M.; Fujita, Y.; Ageta, T.; Kodama, H.
Characteristics of partially purified prolidase and prolinase from the human prostate
Acta Med. Okayama
48
173-179
1994
Homo sapiens
Booth, M.; Donnelly, W.J.; Fhaolain, I.N.; Jennings, P.V.; O'Cuinn, G.
Proline-specific peptidases of Streptococcus cremoris AM2
J. Dairy Res.
57
79-88
1990
Lactococcus cremoris
-
Willingham, K.; Maher, M.J.; Grunden, A.M.; Ghosh, M.; Adams, M.W.; Freeman, H.C.; Guss, J.M.
Crystallization and characterization of the prolidase from Pyrococcus furiosus
Acta Crystallogr. Sect. D
57
428-430
2001
Pyrococcus furiosus
Maher, M.J.; Ghosh, M.; Grunden, A.M.; Menon, A.L.; Adams, M.W.; Freeman, H.C.; Guss, J.M.
Structure of the prolidase from Pyrococcus furiosus
Biochemistry
43
2771-2783
2004
Pyrococcus furiosus, Pyrococcus furiosus (P81535)
Muszynska, A.; Wolczynski, S.; Palka, J.
The mechanism for anthracycline-induced inhibition of collagen biosynthesis
Eur. J. Pharmacol.
411
17-25
2001
Homo sapiens
Karna, E.; Palka, J.; Wolczynski, S.
Doxycycline-induced inhibition of prolidase activity in human skin fibroblasts and its involvement in impaired collagen biosynthesis
Eur. J. Pharmacol.
430
25-31
2001
Homo sapiens
Araki, H.; Li, Y.; Yamamoto, Y.; Haneda, M.; Nishi, K.; Kikkawa, R.; Ohkubo, I.
Purification, molecular cloning, and immunohistochemical localization of dipeptidyl peptidase II from the rat kidney and its identity with quiescent cell proline dipeptidase
J. Biochem.
129
279-288
2001
Homo sapiens
Chiravuri, M.; Lee, H.; Mathieu, S.L.; Huber, B.T.
Homodimerization via a leucine zipper motif is required for enzymatic activity of quiescent cell proline dipeptidase
J. Biol. Chem.
275
26994-26999
2000
Homo sapiens
Chiravuri, M.; Agarraberes, F.; Mathieu, S.L.; Lee, H.; Huber, B.T.
Vesicular localization and characterization of a novel post-proline-cleaving aminodipeptidase, quiescent cell proline dipeptidase
J. Immunol.
165
5695-5702
2000
Homo sapiens
Surazynski, A.; Palka, J.; Wolczynski, S.
Phosphorylation of prolidase increases the enzyme activity
Mol. Cell. Biochem.
220
95-101
2001
Homo sapiens
Wang, W.; Liu, G.; Yamashita, K.; Manabe, M.; Kodama, H.
Characteristics of prolinase against various iminodipeptides in erythrocyte lysates from a normal human and a patient with prolidase deficiency
Clin. Chem. Lab. Med.
42
1102-1108
2004
Homo sapiens
Wang, S.H.; Liu, M.; Chi, M.G.; Wang, Q.D.; Sun, M.J.
Production of human liver prolidase by Saccharomyces cerevisiae as host cells
Acta Pharmacol. Sin.
25
794-800
2004
Homo sapiens
Wang, H.; Kurien, B.T.; Lundgren, D.; Patel, N.C.; Kaufman, K.M.; Miller, D.L.; Porter, A.C.; DSouza, A.; Nye, L.; Tumbush, J.; Hupertz, V.; Kerr, D.S.; Kurono, S.; Matsumoto, H.; Scofield, R.H.
A nonsense mutation of PEPD in four Amish children with prolidase deficiency
Am. J. Med. Genet. A
140
580-585
2006
Homo sapiens
Cauci, S.; McGregor, J.; Thorsen, P.; Grove, J.; Guaschino, S.
Combination of vaginal pH with vaginal sialidase and prolidase activities for prediction of low birth weight and preterm birth
Am. J. Obstet. Gynecol.
192
489-496
2005
Homo sapiens
Park, M.S.; Hill, C.M.; Li, Y.; Hardy, R.K.; Khanna, H.; Khang, Y.H.; Raushel, F.M.
Catalytic properties of the PepQ prolidase from Escherichia coli
Arch. Biochem. Biophys.
429
224-230
2004
Escherichia coli
Verit, F.F.; Geyikli, I.; Yazgan, P.; Celik, A.
Correlations of serum prolidase activity between bone turnover markers and mineral density in postmenopausal osteoporosis
Arch. Gynecol. Obstet.
274
133-137
2006
Homo sapiens
Wang, S.H.; Zhi, Q.W.; Sun, M.J.
Purification and characterization of recombinant human liver prolidase expressed in Saccharomyces cerevisiae
Arch. Toxicol.
79
253-259
2005
Homo sapiens
Lupi, A.; Rossi, A.; Vaghi, P.; Gallanti, A.; Cetta, G.; Forlino, A.
N-benzyloxycarbonyl-L-proline: An in vitro and in vivo inhibitor of prolidase
Biochim. Biophys. Acta
1744
157-163
2005
Homo sapiens, Mus musculus
Duong, H.S.; Zhang, Q.Z.; Le, A.D.; Kelly, A.P.; Kamdar, R.; Messadi, D.V.
Elevated prolidase activity in keloids: correlation with type I collagen turnover
Br. J. Dermatol.
154
820-828
2006
Homo sapiens
Liu, G.; Nakayama, K.; Sagara, Y.; Awata, S.; Yamashita, K.; Manabe, M.; Kodama, H.
Characterization of prolidase activity in erythrocytes from a patient with prolidase deficiency: comparison with prolidase I and II purified from normal human erythrocytes
Clin. Biochem.
38
625-631
2005
Homo sapiens
Liu, G.; Nakayama, K.; Awata, S.; Wang, W.; Yamashita, K.; Manabe, M.; Kodama, H.
Effects of amino acids and its metabolites on prolidase activity against various iminodipeptides in erythrocytes from normal human and a patient with prolidase deficiency
Clin. Chim. Acta
350
211-217
2004
Homo sapiens
Du, X.; Tove, S.; Kast-Hutcheson, K.; Grunden, A.M.
Characterization of the dinuclear metal center of Pyrococcus furiosus prolidase by analysis of targeted mutants
FEBS Lett.
579
6140-6146
2005
Pyrococcus furiosus
Miltyk, W.; Surazynski, A.; Kasprzak, K.S.; Fivash, M.J.; Buzard, G.S.; Phang, J.M.
Inhibition of prolidase activity by nickel causes decreased growth of proline auxotrophic CHO cells
J. Cell. Biochem.
94
1210-1217
2005
Cricetulus griseus
Surazynski, A.; Liu, Y.; Miltyk, W.; Phang, J.M.
Nitric oxide regulates prolidase activity by serine/threonine phosphorylation
J. Cell. Biochem.
96
1086-1094
2005
Mus musculus
Lupi, A.; De Riso, A.; Torre, S.D.; Rossi, A.; Campari, E.; Vilarinho, L.; Cetta, G.; Forlino, A.
Characterization of a new PEPD allele causing prolidase deficiency in two unrelated patients: natural-occurrent mutations as a tool to investigate structure-function relationship
J. Hum. Genet.
49
500-506
2004
Homo sapiens
Surazynski, A.; Sienkiewicz, P.; Wolczynski, S.; Palka, J.
Differential effects of echistatin and thrombin on collagen production and prolidase activity in human dermal fibroblasts and their possible implication in beta1-integrin-mediated signaling
Pharm. Res.
51
217-221
2005
Homo sapiens
Wang, S.H.; Zhi, Q.W.; Sun, M.J.
Dual activities of human prolidase
Toxicol. In Vitro
20
71-77
2006
Homo sapiens
Uramatsu, M.; Liu, G.; Uramatsu, S.; Zhang, M.; Wang, W.; Nakayama, K.; Manabe, M.; Kodama, H.
Different effects of sulfur amino acids on prolidase and prolinase activity in normal and prolidase-deficient human erythrocytes
Clin. Chim. Acta
375
129-135
2007
Homo sapiens
Lee, H.J.; Chen, Y.S.; Chou, C.Y.; Chien, C.H.; Lin, C.H.; Chang, G.G.; Chen, X.
Investigation of the dimer interface and substrate specificity of prolyl dipeptidase DPP8
J. Biol. Chem.
281
38653-38662
2006
Homo sapiens
Lupi, A.; Tenni, R.; Rossi, A.; Cetta, G.; Forlino, A.
Human prolidase and prolidase deficiency: an overview on the characterization of the enzyme involved in proline recycling and on the effects of its mutations
Amino Acids
35
739-752
2008
Homo sapiens, Pyrococcus furiosus
Son, E.D.; Choi, G.H.; Kim, H.; Lee, B.; Chang, I.S.; Hwang, J.S.
Alpha-ketoglutarate stimulates procollagen production in cultured human dermal fibroblasts, and decreases UVB-induced wrinkle formation following topical application on the dorsal skin of hairless mice
Biol. Pharm. Bull.
30
1395-1399
2007
Homo sapiens
Buszman, E.; Wrzesniok, D.; Surazynski, A.; Patka, J.; Moleda, K.
Effect of melanin on netilmicin-induced inhibition of collagen biosynthesis in human skin fibroblasts
Bioorg. Med. Chem.
14
8155-8161
2006
Homo sapiens
Ipcioglu, O.M.; Ozcan, O.; Gultepe, M.; Deniz, O.; Akgul, E.O.
Prolidase activity in serum and pleural fluids in patients with tuberculous pleural effussion
Clin. Biochem.
41
670-675
2008
Homo sapiens
McCaw, D.L.; Chan, A.S.; Stegner, A.L.; Mooney, B.; Bryan, J.N.; Turnquist, S.E.; Henry, C.J.; Alexander, H.; Alexander, S.
Proteomics of canine lymphoma identifies potential cancer-specific protein markers
Clin. Cancer Res.
13
2496-2503
2007
Canis lupus familiaris
Yuan, J.; Wei, H.; Jin, W.; Yang, X.; Wang, E.
Kinetic study of paracetamol on prolidase activity in erythrocytes by capillary electrophoresis with Ru(bpy)3 2+ electrochemiluminescence detection
Electrophoresis
27
4047-4051
2006
Homo sapiens
Lupi, A.; Della Torre, S.; Campari, E.; Tenni, R.; Cetta, G.; Rossi, A.; Forlino, A.
Human recombinant prolidase from eukaryotic and prokaryotic sources. Expression, purification, characterization and long-term stability studies
FEBS J.
273
5466-5478
2006
Homo sapiens
Yang, S.I.; Tanaka, T.
Characterization of recombinant prolidase from Lactococcus lactis - changes in substrate specificity by metal cations, and allosteric behavior of the peptidase
FEBS J.
275
271-280
2008
Lactococcus lactis (A8WBX8), Lactococcus lactis NRRL B-1821 (A8WBX8), Lactococcus lactis NRRL B-1821
Cechowska-Pasko, M.; Palka, J.; Wojtukiewicz, M.Z.
Enhanced prolidase activity and decreased collagen content in breast cancer tissue
Int. J. Exp. Pathol.
87
289-296
2006
Homo sapiens
Le Marrec, C.; Bon, E.; Lonvaud-Funel, A.
Tolerance to high osmolality of the lactic acid bacterium Oenococcus oeni and identification of potential osmoprotectants
Int. J. Food Microbiol.
115
335-342
2007
Oenococcus oeni
Galicka, A.; Nazaruk, J.
Stimulation of collagen biosynthesis by flavonoid glycosides in skin fibroblasts of osteogenesis imperfecta type I and the potential mechanism of their action
Int. J. Mol. Med.
20
889-895
2007
Homo sapiens
Miltyk, W.; Karna, E.; Palka, J.A.
Prolidase-independent mechanism of camptothecin-induced inhibition of collagen biosynthesis in cultured human skin fibroblasts
J. Biochem.
141
287-292
2007
Homo sapiens
Karna, E.; Miltyk, W.; Surazynski, A.; Patka, J.A.
Protective effect of hyaluronic acid on interleukin-1-induced deregulation of beta1-integrin and insulin-like growth factor-I receptor signaling and collagen biosynthesis in cultured human chondrocytes
Mol. Cell. Biochem.
308
57-64
2008
Homo sapiens
Citak Kurt, A.N.; Ustundag, B.; Akarsu, S.; Kurt, A.; Yilmaz, E.; Ocal, C.; Aygun, A.D.
Cord blood prolidase activity correlates with gestational age and birth weight
Neonatology
94
110-112
2008
Homo sapiens
Liu, G.; Nakayama, K.; Awata, S.; Tang, S.; Kitaoka, N.; Manabe, M.; Kodama, H.
Prolidase isoenzymes in the rat: their organ distribution, developmental change and specific inhibitors
Pediatr. Res.
62
54-59
2007
Rattus norvegicus
Mittal, S.; Song, X.; Vig, B.S.; Amidon, G.L.
Proline prodrug of melphalan targeted to prolidase, a prodrug activating enzyme overexpressed in melanoma
Pharm. Res.
24
1290-1298
2007
Homo sapiens, Sus scrofa
Uramatsu, S.; Liu, G.; Yang, Q.; Uramatsu, M.; Chi, H.; Lu, J.; Yamashita, K.; Kodama, H.
Characterization of prolidase I and II purified from normal human erythrocytes: comparison with prolidase in erythrocytes from a patient with prolidase deficiency
Amino Acids
37
543-551
2009
Homo sapiens
Rabus, M.; Demirbag, R.; Yildiz, A.; Tezcan, O.; Yilmaz, R.; Ocak, A.R.; Alp, M.; Erel, O.; Aksoy, N.; Yakut, C.
Association of prolidase activity, oxidative parameters, and presence of atrial fibrillation in patients with mitral stenosis
Arch. Med. Res.
39
519-524
2008
Homo sapiens
Dunn, R.; Dolianitis, C.
Prolidase deficiency: the use of topical proline for treatment of leg ulcers
Australas. J. Dermatol.
49
237-238
2008
Homo sapiens
Zhang, G.; Chen, J.A.; Tanaka, T.
Deregulation of allosteric response of Lactococcus lactis prolidase and its effects on enzyme activity
Biochim. Biophys. Acta
1794
968-975
2009
Lactococcus lactis
Yildiz, A.; Demirbag, R.; Yilmaz, R.; Gur, M.; Altiparmak, I.H.; Akyol, S.; Aksoy, N.; Ocak, A.R.; Erel, O.
The association of serum prolidase activity with the presence and severity of coronary artery disease
Coron. Artery Dis.
19
319-325
2008
Homo sapiens
Kayadibi, H.; Gueltepe, M.; Yasar, B.; Ince, A.T.; Ozcan, O.; Ipcioglu, O.M.; Kurdas, O.O.; Bolat, B.; Benek, Y.Z.; Guveli, H.; Atalay, S.; Ozkara, S.; Keskin, O.
Diagnostic value of serum prolidase enzyme activity to predict the liver histological lesions in non-alcoholic fatty liver disease: A surrogate marker to distinguish steatohepatitis from simple steatosis
Digest. Dis. Sci.
54
1764-1771
2008
Homo sapiens
Colonna, C.; Conti, B.; Perugini, P.; Pavanetto, F.; Modena, T.; Dorati, R.; Iadarola, P.; Genta, I.
Ex vivo evaluation of prolidase loaded chitosan nanoparticles for the enzyme replacement therapy
Eur. J. Pharm. Biopharm.
70
58-65
2008
Homo sapiens
Colonna, C.; Conti, B.; Perugini, P.; Pavanetto, F.; Modena, T.; Dorati, R.; Iadarola, P.; Genta, I.
Site-directed PEGylation as successful approach to improve the enzyme replacement in the case of prolidase
Int. J. Pharm.
358
230-237
2008
Sus scrofa
Miltyk, W.; Surazynski, A.; Grabowska, J.; Palka, J.A.
Prolidase dependent inhibition of collagen biosynthesis in Chinese hamster ovary cells
J. Biochem.
144
409-414
2008
Sus scrofa
Zhou, L.; Yuan, J.; Yin, J.; Wang, E.
Kinetic study of prolidase activity in erythrocytes against different substrates using capillary electrophoresis with electrochemiluminescence detection
J. Chromatogr. A
1200
255-259
2008
Homo sapiens
Cakmak, A.; Zeyrek, D.; Atas, A.; Celik, H.; Aksoy, N.; Erel, O.
Serum prolidase activity and oxidative status in patients with bronchial asthma
J. Clin. Lab. Anal.
23
132-138
2009
Homo sapiens
Bielawski, K.; Bielawska, A.; S?odownik, T.; Bo?kun-Skornicka, U.; Muszy?ska, A.
Proline-linked nitrosoureas as prolidase-convertible prodrugs in human breast cancer cells
Pharmacol. Rep.
60
171-182
2008
Homo sapiens, Sus scrofa
Theriot, C.M.; Tove, S.R.; Grunden, A.M.
Biotechnological applications of recombinant microbial prolidases
Adv. Appl. Microbiol.
68
99-132
2009
Alteromonas sp., Cavia porcellus, Homo sapiens, Lacticaseibacillus casei, Lactobacillus delbrueckii, Lactococcus lactis, Stenotrophomonas maltophilia, Pyrococcus furiosus, Alteromonas sp. JD6.5, Lacticaseibacillus casei IFPL 731
Falik-Zaccai, T.; Khayat, M.; Luder, A.; Frenkel, P.; Magen, D.; Brik, R.; Gershoni-Baruch, R.; Mandel, H.
A broad spectrum of developmental delay in a large cohort of prolidase deficiency patients demonstrates marked interfamilial and intrafamilial phenotypic variability
Am. J. Med. Genet. B Neuropsychiatr. Genet.
153
46-56
2010
Homo sapiens
Theriot, C.M.; Tove, S.R.; Grunden, A.M.
Characterization of two proline dipeptidases (prolidases) from the hyperthermophilic archaeon Pyrococcus horikoshii
Appl. Microbiol. Biotechnol.
86
177-188
2010
Pyrococcus horikoshii (O58885), Pyrococcus horikoshii (O59565), Pyrococcus horikoshii (P81535), Pyrococcus horikoshii, Pyrococcus horikoshii ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3 / 700860D-5 (O58885), Pyrococcus horikoshii ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3 / 700860D-5 (P81535)
Theriot, C.M.; Du, X.; Tove, S.R.; Grunden, A.M.
Improving the catalytic activity of hyperthermophilic Pyrococcus prolidases for detoxification of organophosphorus nerve agents over a broad range of temperatures
Appl. Microbiol. Biotechnol.
87
1715-1726
2010
Pyrococcus furiosus, Pyrococcus furiosus (P81535)
Vural, M.; Toy, H.; Camuzcuoglu, H.; Aksoy, N.
Comparison of prolidase enzyme activities of maternal serum and placental tissue in patients with early pregnancy failure
Arch. Gynecol. Obstet.
283
953-958
2011
Homo sapiens
Vyas, N.K.; Nickitenko, A.; Rastogi, V.K.; Shah, S.S.; Quiocho, F.A.
Structural insights into the dual activities of the nerve agent degrading organophosphate anhydrolase/prolidase
Biochemistry
49
547-559
2010
Alteromonas sp., Alteromonas sp. JD6.5
Hu, K.; Tanaka, T.
S1 site residues of Lactococcus lactis prolidase affect substrate specificity and allosteric behaviour
Biochim. Biophys. Acta
1794
1715-1724
2009
Lactococcus lactis
Bitiren, M.; Karakilcik, A.Z.; Zerin, M.; Ozardali, I.; Selek, S.; Nazliguel, Y.; Ozgonul, A.; Musa, D.; Uzunkoy, A.
Protective effects of selenium and vitamin e combination on experimental colitis in blood plasma and colon of rats
Biol. Trace Elem. Res.
136
87-95
2010
Rattus norvegicus
Chi, H.; Lu, J.; Liu, G.; Tong, J.; Nakayama, K.; Yamashita, K.; Kitaoka, N.; Kodama, H.
Activity of prolidase isoenzymes in the rat brain: subcellular and regional distribution during development
Brain Res.
1303
8-14
2009
Rattus norvegicus
Besio, R.; Alleva, S.; Forlino, A.; Lupi, A.; Meneghini, C.; Minicozzi, V.; Profumo, A.; Stellato, F.; Tenni, R.; Morante, S.
Identifying the structure of the active sites of human recombinant prolidase
Eur. Biophys. J.
39
935-945
2010
Homo sapiens (P12955), Homo sapiens
Camuzcuoglu, H.; Arioz, D.T.; Toy, H.; Kurt, S.; Celik, H.; Aksoy, N.
Assessment of preoperative serum prolidase activity in epithelial ovarian cancer
Eur. J. Obstet. Gynecol. Reprod. Biol.
147
97-100
2009
Homo sapiens
Klar, A.; Navon-Elkan, P.; Rubinow, A.; Branski, D.; Hurvitz, H.; Christensen, E.; Khayat, M.; Falik-Zaccai, T.C.
Prolidase deficiency: it looks like systemic lupus erythematosus but it is not
Eur. J. Pediatr.
169
727-732
2010
Homo sapiens
Vural, M.; Camuzcuoglu, H.; Toy, H.; Aksoy, N.
Amniotic fluid prolidase activity and oxidative status in neural tube defects
Fetal. Diagn. Ther.
28
34-39
2010
Homo sapiens
Toy, H.; Camuzcuoglu, H.; Camuzcuoglu, A.; Celik, H.; Aksoy, N.
Decreased serum prolidase activity and increased oxidative stress in early pregnancy loss
Gynecol. Obstet. Invest.
69
122-127
2010
Homo sapiens
Savas, M.; Yeni, E.; Celik, H.; Ciftci, H.; Utangac, M.; Oncel, H.; Altunkol, A.; Verit, A.
The association of serum prolidase activity and erectile dysfunction
J. Androl.
31
146-154
2010
Homo sapiens
Horoz, M.; Aslan, M.; Bolukbas, F.F.; Bolukbas, C.; Nazligul, Y.; Celik, H.; Aksoy, N.
Serum prolidase enzyme activity and its relation to histopathological findings in patients with non-alcoholic steatohepatitis
J. Clin. Lab. Anal.
24
207-211
2010
Homo sapiens
Cakmak, A.; Soker, M.; Koc, A.; Aksoy, N.
Prolidase activity and oxidative status in patients with thalassemia major
J. Clin. Lab. Anal.
24
6-11
2010
Homo sapiens
Toy, H.; Camuzcuoglu, H.; Arioz, D.T.; Kurt, S.; Celik, H.; Aksoy, N.
Serum prolidase activity and oxidative stress markers in pregnancies with intrauterine growth restricted infants
J. Obstet. Gynaecol. Res.
35
1047-1053
2009
Homo sapiens
Karna, E.; Szoka, L.; Palka, J.A.
Betulinic acid inhibits the expression of hypoxia-inducible factor 1alpha and vascular endothelial growth factor in human endometrial adenocarcinoma cells
Mol. Cell. Biochem.
340
15-20
2010
Homo sapiens
Akcakoyun, M.; Pala, S.; Esen, O.; Acar, G.; Kargin, R.; Emiroglu, Y.; Tigen, K.; Ozcan, O.; Ipcioglu, O.M.; Esen, A.M.
Dilatation of the ascending aorta is associated with low serum prolidase activity
Tohoku J. Exp. Med.
220
273-277
2010
Homo sapiens
Theriot, C.M.; Semcer, R.L.; Shah, S.S.; Grunden, A.M.
Improving the catalytic activity of hyperthermophilic Pyrococcus horikoshii prolidase for detoxification of organophosphorus nerve agents over a broad range of temperatures
Archaea
2011
565127
2011
Pyrococcus horikoshii (O58691), Pyrococcus horikoshii, Pyrococcus horikoshii DSM 12428 (O58691)
Kumar, A.; Are, V.; Ghosh, B.; Agrawal, U.; Jamdar, S.; Makde, R.; Sharma, S.
Crystallization and preliminary X-ray diffraction analysis of Xaa-Pro dipeptidase from Xanthomonas campestris
Acta Crystallogr. Sect. F
70
1268-1271
2014
Xanthomonas campestris (Q8P839), Xanthomonas campestris, Xanthomonas campestris ATCC 33913 (Q8P839), Xanthomonas campestris DSM 3586 (Q8P839)
Kumar, A.; Are, V.N.; Ghosh, B.; Agrawal, U.; Jamdar, S.N.; Makde, R.D.; Sharma, S.M.
Crystallization and preliminary X-ray diffraction analysis of Xaa-Pro dipeptidase from Xanthomonas campestris
Acta Crystallogr. Sect. F
70
1268-1271
2014
Xanthomonas campestris pv. campestris (Q8P839), Xanthomonas campestris pv. campestris P 25 (Q8P839), Xanthomonas campestris pv. campestris NCPPB 528 (Q8P839), Xanthomonas campestris pv. campestris LMG 568 (Q8P839), Xanthomonas campestris pv. campestris ATCC 33913 (Q8P839), Xanthomonas campestris pv. campestris DSM 3586 (Q8P839)
Are, V.N.; Kumar, A.; Kumar, S.; Goyal, V.D.; Ghosh, B.; Bhatnagar, D.; Jamdar, S.N.; Makde, R.D.
Crystal structure and biochemical investigations reveal novel mode of substrate selectivity and illuminate substrate inhibition and allostericity in a subfamily of Xaa-Pro dipeptidases
Biochim. Biophys. Acta
1865
153-164
2017
Mycobacterium tuberculosis (P9WHS7), Mycobacterium tuberculosis, Xanthomonas campestris pv. campestris (Q8P839), Mycobacterium tuberculosis ATCC 25618 (P9WHS7), Xanthomonas campestris pv. campestris DSM 3586 (Q8P839)
Miyabe, R.; Takahashi, Y.; Matsufuji, H.; Ogihara, J.; Ito, K.; Kawai, Y.; Masuda, T.; Suzuki, K.; Oda, M.
Purification and partial characterization of an X-prolyl-dipeptidyl aminopeptidase from lactobacillus gasseri me-284
Food Sci. Technol. Res.
21
445-451
2015
Lactobacillus gasseri, Lactobacillus gasseri me-284, Lactobacillus gasseri ATCC 33323
-
Arreola, R.; Villalpando, J.L.; Puente-Rivera, J.; Morales-Montor, J.; Rudino-Pinera, E.; Alvarez-Sanchez, M.E.
Trichomonas vaginalis metalloproteinase TvMP50 is a monomeric aminopeptidase P-like enzyme
Mol. Biotechnol.
60
563-575
2018
Trichomonas vaginalis (A2F8Y2), Trichomonas vaginalis
Are, V.; Jamdar, S.; Ghosh, B.; Goyal, V.; Kumar, A.; Neema, S.; Gadre, R.; Makde, R.
Crystal structure of a novel prolidase from Deinococcus radiodurans identifies new subfamily of bacterial prolidases
Proteins
85
2239-2251
2017
Deinococcus radiodurans
Are, V.; Kumar, A.; Goyal, V.; Gotad, S.; Ghosh, B.; Gadre, R.; Jamdar, S.; Makde, R.
Structures and activities of widely conserved small prokaryotic aminopeptidases-P clarify classification of M24B peptidases
Proteins
87
212-225
2018
Pyrococcus furiosus (P81535), Pyrococcus furiosus ATCC 43587 (P81535), Pyrococcus furiosus JCM 8422 (P81535), Pyrococcus furiosus Vc1 (P81535)
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