Reference on EC 3.4.11.7 - glutamyl aminopeptidase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Petrovic, S.; Vitale, L.
Purification and properties of glutamyl aminopeptidase from chicken egg-white
Comp. Biochem. Physiol. B
95
589-595
1990
Gallus gallus
Lalu, K.; Lampelo, S.; Vanha-Perttula, T.
Characterization of three aminopeptidases purified from maternal serum
Biochim. Biophys. Acta
873
190-197
1986
Homo sapiens
Exterkate, F.A.; DeVeer, G.J.C.M.
Efficient implementation of consecutive reactions by peptidases at the periphery of the Streptococcus cremoris membrane
Appl. Environ. Microbiol.
53
1482-1486
1987
Lactococcus cremoris
Exterkate, F.A.; DeVeer, G.J.C.M.
Purification and some properties of a membrane-bound aminopeptidase A from Streptococcus cremoris
Appl. Environ. Microbiol.
53
577-583
1987
Lactococcus cremoris
Lalu, K.; Lampelo, S.; Nummelin-Kortelainen, M.; Vanha-Perttula, T.
Purification and partial characterization of aminopeptidase A from the serum of pregnant and non-pregnant women
Biochim. Biophys. Acta
789
324-333
1984
Homo sapiens
Stewart, J.R.; Kenny, A.J.
Proteins of the kidney microvillar membrane. Biosynthesis of endopeptidase-24.11, dipeptidylpeptidase IV and aminopeptidases N and A in pig kidney slices
Biochem. J.
224
549-558
1984
Sus scrofa
Danielsen, E.M.; Sjoestroem, H.; Noren, O.
Biosynthesis of intestinal microvillar proteins. Pulse-chase labelling studies on maltase-glucoamylase, aminopeptidase A and dipeptidyl peptidase IV
Biochem. J.
210
389-393
1983
Sus scrofa
Tobe, H.; Morishima, H.; Aoyagi, T.; Umezawa, H.; Ishiki, K.; Nakamura, K.; Yoshioka, T.; Shimauchi, Y.; Inui, T.
Synthesis and structure-activity relationships of amastatin analogues, inhibitors of aminopeptidase A
Agric. Biol. Chem.
46
1865-1872
1982
Homo sapiens
-
Mizutani, S.; Okano, K.; Hasegawa, E.; Sakura, H.; Yamada, M.
Aminopeptidase A in human placenta
Biochim. Biophys. Acta
678
168-170
1981
Homo sapiens
Sterchi, E.E.; Green, J.R.; Lentze, M.J.
The distribution of four peptide hydrolases along the small intestine of the adult human
Biochem. Soc. Trans.
9
130-131
1981
Homo sapiens
Feracci, H.; Benajiba, A.; Gorvel, J.P.; Doumeng, C.; Maroux, S.
Enzymatic and immunological properties of the protease form of aminopeptidase N and A from pig and rabbit intestinal brush border
Biochim. Biophys. Acta
658
148-157
1981
Oryctolagus cuniculus, Sus scrofa
Danielsen, E.M.; Noren, O.; Sjoestroem, H.; Ingram, J.; Kenny, A.J.
Proteins of the kidney microvillar membrane. Aspartate aminopeptidase: purification by immunoadsorbent chromatography and properties of the detergent- and proteinase-solubilized forms
Biochem. J.
189
591-603
1980
Sus scrofa
Gorvel, J.P.; Benajiba, A.; Maroux, S.
Purification and characterization of the rabbit intestinal brush-border aminopeptidase A
Biochim. Biophys. Acta
615
271-274
1980
Oryctolagus cuniculus
Benajiba, A.; Maroux, S.
Purification and characterization of an aminopeptidase A from hog intestinal brush-border membrane
Eur. J. Biochem.
107
381-388
1980
Sus scrofa
Tobe, H.; Kojima, F.; Aoyagi, T.; Umezawa, H.
Purification by affinity chromatography using amastatin and properties of aminopeptidase A from pig kidney
Biochim. Biophys. Acta
613
459-468
1980
Sus scrofa
DelVecchio, P.J.; Ryan, J.W.; Chung, A.; Ryan, U.S.
Capillaries of the adrenal cortex possess aminopeptidase A and angiotensin-converting-enzyme activities
Biochem. J.
186
605-608
1980
Rattus norvegicus
Cheung, H.S.; Cushman, D.W.
A soluble aspartate aminopeptidase from dog kidney
Biochim. Biophys. Acta
242
190-193
1971
Canis lupus familiaris
Nagatsu, I.; Nagatsu, T.; Yamamoto, T.; Glenner, G.G.; Mehl, J.W.
Purification of aminopeptidase A in human serum and degradation of angiotensin II by the purified enzyme
Biochim. Biophys. Acta
198
255-270
1970
Homo sapiens
Glenner, G.G.; McMillan, P.J.; Folk, J.E.
A mammalian peptidase specific for the hydrolysis of N-terminal alpha-L-glutamyl and aspartyl residue
Nature
194
867
1962
Rattus norvegicus
Zini, S.; Fournie-Zaluski, M.C.; Chauvel, E.; Roques, B.P.; Corvol, P.; Llorens-Cortes, C.
Identification of metabolic pathways of brain angiotensin II and III using specific aminopeptidase inhibitors: predominant role of angiotensin III in the control of vasopressin release
Proc. Natl. Acad. Sci. USA
93
11968-11973
1996
Mus musculus
Vazeux, G.; Wilk, S.; Wilk, E.; Corvol, P.; Llorens-Cortez, C.
Production and properties of a recombinant soluble form of aminopeptidase A
Eur. J. Biochem.
254
671-678
1998
Mus musculus
Yoshpe-Besancon, I.; Auriol, D.; Paul, F.; Monsan, P.; Gripon, J.C.; Ribadeau-Dumas, B.
Purification and characterization of an aminopeptidase A from Staphylococcus chromogenes and its use for the synthesis of amino-acid derivatives and dipeptides
Eur. J. Biochem.
211
105-110
1993
Staphylococcus chromogenes
Herzig, C.M.; Schoeppe, W.; Scherberich, J.E.
Angiotensinase A (aminopeptidase A): Properties of chromatographically purified isoforms from human kidney
J. Chromatogr.
625
73-82
1992
Homo sapiens
Kinkowstrom, A.M.; Terra, W.R.; Ferreira, C.
Aminopeptidase A from Phynchosciara americana (diptera) larval midguts: Properties and midgut distribution
Arch. Insect Biochem. Physiol.
27
301-315
1994
Rhynchosciara americana
-
Llorens-Cortes, C.
Identification of metabolic pathways of brain angiotensin II and III using specific aminopeptidase inhibitors: Predominant role of angiotensin III in the control of vasopressin release
C. R. Seances Soc. Biol. Fil.
192
607-618
1998
Mus musculus
Niven, G.W.
Purification and characterization of aminopeptidase A from Lactococcus lactis subsp. lactis NCDO 712
J. Gen. Microbiol.
137
1207-1212
1991
Lactococcus lactis
-
Scherberich, J.E.; Wiemer, J.; Schoeppe, W.
Biochemical and immunological properties of urinary angiotensinase A and dipeptidylaminopeptidase IV. Their use as markers in patients with renal cell injury
Eur. J. Clin. Chem. Clin. Biochem.
30
663-668
1992
Homo sapiens
Wu, Q.; Lahti, J.M.; Air, G.M.; Burrows, P.D.; Cooper, M.D.
Molecular cloning of the murine BP-1/6C3 antigen: a member of the zinc-dependent metallopeptidase family
Proc. Natl. Acad. Sci. USA
87
993-997
1990
Mus musculus
Ofner, L.D.; Hooper, N.M.
The C-terminal domain, but not the interchain disulphide, is required for the activity and intracellular trafficking of aminopeptidase A
Biochem. J.
362
191-197
2002
Mus musculus (P16406), Mus musculus
Georgiadis, D.; Vazeux, G.; Llorens-Cortes, C.; Yiotakis, A.; Dive, V.
Potent and selective inhibition of zinc aminopeptidase A (EC 3.4.11.7, APA) by glutamyl aminophosphinic peptides: importance of glutamyl aminophosphinic residue in the P1 position
Biochemistry
39
1152-1155
2000
Mus musculus (P16406)
Iturrioz, X.; Vazeux, G.; Celerier, J.; Corvol, P.; Llorens-Cortes, C.
Histidine 450 plays a critical role in catalysis and, with Ca2+, contributes to the substrate specificity of aminopeptidase A
Biochemistry
39
3061-3068
2000
Mus musculus (P16406), Mus musculus
Iturrioz, X.; Rozenfeld, R.; Michaud, A.; Corvol, P.; Llorens-Cortes, C.
Study of asparagine 353 in aminopeptidase A: characterization of a novel motif (GXMEN) implicated in exopeptidase specificity of monozinc aminopeptidases
Biochemistry
40
14440-14448
2001
Mus musculus (P16406)
Rozenfeld, R.; Iturrioz, X.; Okada, M.; Maigret, B.; Llorens-Cortes, C.
Contribution of molecular modeling and site-directed mutagenesis to the identification of a new residue, glutamate 215, involved in the exopeptidase specificity of aminopeptidase A
Biochemistry
42
14785-14793
2003
Mus musculus (P16406)
Healy, D.P.
Regulation of aminopeptidase A activity by angiotensin II: Possible role in animal models of hypertension
Int. Congr. Ser.
1218
55-65
2001
Mus musculus (P16406)
-
Rozenfeld, R.; Iturrioz, X.; Maigret, B.; Llorens-Cortes, C.
Contribution of molecular modeling and site-directed mutagenesis to the identification of two structural residues, Arg-220 and Asp-227, in aminopeptidase A
J. Biol. Chem.
277
29242-29252
2002
Mus musculus (P16406)
David, C.; Bischoff, L.; Meudal, H.; Mothe, A.; De Mota, N.; DaNascimento, S.; Llorens-Cortes, C.; Fournie-Zaluski, M.C.; Roques, B.P.
Investigation of subsite preferences in aminopeptidase A (EC 3.4.11.7) led to the design of the first highly potent and selective inhibitors of this enzyme
J. Med. Chem.
42
5197-5211
1999
Mus musculus (P16406)
O-Wang, J.; Copper, M.D.
Aminopeptidase A
Handbook of Proteolytic Enyzmes (2nd Edition)
1
299-303
2004
Cavia porcellus
-
Iturrioz, X.; Reaux-Le Goazigo, A.; Llorens-Cortes, C.
Aminopeptidase inhibitors as anti-hypertensive drugs
Aminopetidases in Biology and Disease (Hooper, N. M. ; Lendaechel, U. , eds. ) Springer
2
229-250
2004
Homo sapiens, Mus musculus, Rattus norvegicus, Sus scrofa
-
Banegas, I.; Prieto, I.; Alba, F.; Vives, F.; Araque, A.; Segarra, A.B.; Duran, R.; de Gasparo, M.; Ramirez, M.
Angiotensinase activity is asymmetrically distributed in the amygdala, hippocampus and prefrontal cortex of the rat
Behav. Brain Res.
156
321-326
2005
Rattus norvegicus
Mitsui, T.; Nomura, S.; Itakura, A.; Mizutani, S.
Role of aminopeptidases in the blood pressure regulation
Biol. Pharm. Bull.
27
768-771
2004
Rattus norvegicus
Harata, T.; Ando, H.; Iwase, A.; Nagasaka, T.; Mizutani, S.; Kikkawa, F.
Localization of angiotensin II, the AT1 receptor, angiotensin-converting enzyme, aminopeptidase A, adipocyte-derived leucine aminopeptidase, and vascular endothelial growth factor in the human ovary throughout the menstrual cycle
Fertil. Steril.
86
433-439
2006
Homo sapiens
Adang, M.J.
Aminopeptidase A
Handbook of Proteolytic Enzymes (2nd Edition)
1
299-303
2004
Mus musculus (P16406)
-
Adang, M.J.
Aminopeptidase A
Handbook of Proteolytic Enzymes (Barrett, J. ; Rawlings, N. D. ; Woessner, J. F. , eds) Academic Press
2nd. Ed. 1
299-303
2004
Rattus norvegicus
-
Niven, G.W.
Glutamyl aminopeptidase (Lactococcus)
Handbook of Proteolytic Enzymes (Barrett, J. ; Rawlings, N. D. ; Woessner, J. F. , eds) Academic Press
2nd. Ed. 1
965-968
2004
Leuconostoc mesenteroides, Streptococcus pneumoniae, Lactococcus lactis, Streptococcus agalactiae, Streptococcus pyogenes, Streptococcus mutans, Streptococcus suis
-
Fricke, B.; Aurich, H.
Periplasmic aminopeptidases in Acinetobacter calcoaceticus and Pseudomonas aeruginosa
J. Basic Microbiol.
33
291-299
1993
Acinetobacter calcoaceticus, Pseudomonas aeruginosa, Acinetobacter calcoaceticus 69-V
Rozenfeld, R.; Muller, L.; El Messari, S.; Llorens-Cortes, C.
The C-terminal domain of aminopeptidase A is an intramolecular chaperone required for the correct folding, cell surface expression, and activity of this monozinc aminopeptidase
J. Biol. Chem.
279
43285-43295
2004
Mus musculus
Goto, Y.; Hattori, A.; Ishii, Y.; Mizutani, S.; Tsujimoto, M.
Enzymatic properties of aminopeptidase A: regulation of its enzymatic activity by calcium and angiotensin IV
J. Biol. Chem.
281
23503-23513
2006
Homo sapiens
Agirregoitia, N.; Laiz-Carrion, R.; Varona, A.; Rio, M.P.; Mancera, J.M.; Irazusta, J.
Distribution of peptidase activity in teleost and rat tissues
J. Comp. Physiol. B
175
433-444
2005
Oncorhynchus mykiss, Rattus norvegicus, Sparus aurata
Dijkman, H.B.; Assmann, K.J.; Steenbergen, E.J.; Wetzels, J.F.
Expression and effect of inhibition of aminopeptidase-A during nephrogenesis
J. Histochem. Cytochem.
54
253-262
2006
Mus musculus, Mus musculus BALB/c
Larrinaga, G.; Callado, L.F.; Agirregoitia, N.; Varona, A.; Gil, J.
Subcellular distribution of membrane-bound aminopeptidases in the human and rat brain
Neurosci. Lett.
383
136-140
2005
Homo sapiens, Rattus norvegicus
Fournie-Zaluski, M.C.; Fassot, C.; Valentin, B.; Djordjijevic, D.; Reaux-Le Goazigo, A.; Corvol, P.; Roques, B.P.; Llorens-Cortes, C.
Brain renin-angiotensin system blockade by systemically active aminopeptidase A inhibitors: A potential treatment of salt-dependent hypertension
Proc. Natl. Acad. Sci. USA
101
7775-7780
2004
Mus musculus, Rattus norvegicus
Tonna, S.; Dandapani, S.V.; Uscinski, A.; Appel, G.B.; Schloendorff, J.S.; Zhang, K.; Denker, B.M.; Pollak, M.R.
Functional genetic variation in aminopeptidase A (ENPEP): Lack of clear association with focal and segmental glomerulosclerosis (FSGS)
Gene
410
44-52
2008
Homo sapiens
Teuscher, F.; Lowther, J.; Skinner-Adams, T.S.; Spielmann, T.; Dixon, M.W.; Stack, C.M.; Donnelly, S.; Mucha, A.; Kafarski, P.; Vassiliou, S.; Gardiner, D.L.; Dalton, J.P.; Trenholme, K.R.
The M18 aspartyl aminopeptidase of the human malaria parasite Plasmodium falciparum
J. Biol. Chem.
282
30817-30826
2007
Plasmodium falciparum (Q8I2J3), Plasmodium falciparum
Segarra, A.B.; Wangensteen, R.; Ramirez, M.; Banegas, I.; Hermoso, F.; Vargas, F.; Vives, F.; Duran, R.; Alba, F.; de Gasparo, M.; Prieto, I.
Atrial angiotensinase activity in hypothyroid, euthyroid, and hyperthyroid rats
J. Cardiovasc. Pharmacol.
48
117-120
2006
Rattus norvegicus
Banegas, I.; Prieto, I.; Vives, F.; Alba, F.; de Gasparo, M.; Segarra, A.B.; Hermoso, F.; Duran, R.; Ramirez, M.
Brain aminopeptidases and hypertension
J. Renin Angiotensin Aldosterone Syst.
7
129-134
2006
Rattus norvegicus
Tsujimoto, M.; Goto, Y.; Maruyama, M.; Hattori, A.
Biochemical and enzymatic properties of the M1 family of aminopeptidases involved in the regulation of blood pressure
Heart Fail. Rev.
13
285-291
2007
Homo sapiens, Mus musculus, Rattus norvegicus
Bodineau, L.; Frugiere, A.; Marc, Y.; Claperon, C.; Llorens-Cortes, C.
Aminopeptidase A inhibitors as centrally acting antihypertensive agents
Heart Fail. Rev.
13
311-319
2008
Mus musculus, Rattus norvegicus
Bodineau, L.; Frugiere, A.; Marc, Y.; Inguimbert, N.; Fassot, C.; Balavoine, F.; Roques, B.; Llorens-Cortes, C.
Orally Active Aminopeptidase A Inhibitors Reduce Blood Pressure. A New Strategy for Treating Hypertension
Hypertension
51
1318-1325
2008
Mus musculus, Rattus norvegicus
Padia, S.H.; Kemp, B.A.; Howell, N.L.; Fournie-Zaluski, M.C.; Roques, B.P.; Carey, R.M.
Conversion of renal angiotensin II to angiotensin III is critical for AT2 receptor-mediated natriuresis in rats
Hypertension
51
460-465
2008
Rattus norvegicus
Zotta, T.; Ricciardi, A.; Parente, E.
Enzymatic activities of lactic acid bacteria isolated from Cornetto di Matera sourdoughs
Int. J. Food Microbiol.
115
165-172
2007
Leuconostoc mesenteroides, Lactiplantibacillus plantarum, Latilactobacillus curvatus, Lactiplantibacillus pentosus, Lactiplantibacillus paraplantarum, Weissella cibaria, Latilactobacillus curvatus DBPZ1009, Lactiplantibacillus plantarum DBPZ0987, Lactiplantibacillus paraplantarum DBPZ0997, Leuconostoc mesenteroides DBPZ0985, Lactiplantibacillus pentosus DBPZ0984
Goto, Y.; Hattori, A.; Mizutani, S.; Tsujimoto, M.
Asparatic acid 221 is critical in the calcium-induced modulation of the enzymatic activity of human aminopeptidase A
J. Biol. Chem.
282
37074-37081
2007
Homo sapiens
Llorens-Cortes, C.; Kordon, C.
Jacques Benoit lecture: the neuroendocrine view of the angiotensin and apelin systems
J. Neuroendocrinol.
20
279-289
2008
Rattus norvegicus
Narvaez-Vasquez, J.; Tu, C.J.; Park, S.Y.; Walling, L.L.
Targeting and localization of wound-inducible leucine aminopeptidase A in tomato leaves
Planta
227
341-351
2008
Solanum lycopersicum
Faber, F.; Gembardt, F.; Sun, X.; Mizutani, S.; Siems, W.E.; Walther, T.
Lack of angiotensin II conversion to angiotensin III increases water but not alcohol consumption in aminopeptidase A-deficient mice
Regul. Pept.
136
130-137
2006
Mus musculus
Ogawa, Y.; Murayama, N.; Fujita, Y.; Yanoshita, R.
Characterization and cDNA cloning of aminopeptidase A from the venom of Gloydius blomhoffi brevicaudus
Toxicon
49
1172-1181
2007
Bothrops jararaca, Crotalus atrox, Gloydius blomhoffii, Gloydius brevicaudus, Protobothrops flavoviridis
Claperon, C.; Rozenfeld, R.; Iturrioz, X.; Inguimbert, N.; Okada, M.; Roques, B.; Maigret, B.; Llorens-Cortes, C.
Asp218 participates with Asp213 to bind a Ca2+ atom into the S1 subsite of aminopeptidase A: a key element for substrate specificity
Biochem. J.
416
37-46
2008
Mus musculus (P16406), Mus musculus
Wu, Y.; Xiao, J.; Wu, L.; Tian, W.; Liu, L.
Expression of glutamyl aminopeptidase by osteogenic induction in rat bone marrow stromal cells
Cell Biol. Int.
32
748-753
2008
Rattus norvegicus
Ishii, M.; Hattori, A.; Numaguchi, Y.; Tsujimoto, M.; Ishiura, S.; Kobayashi, H.; Murohara, T.; Wright, J.W.; Mizutani, S.
The effect of recombinant aminopeptidase A on hypertension in spontaneously hypertensive rats: its effect in comparison with candesartan
Horm. Metab. Res.
40
887-891
2008
Homo sapiens
Claperon, C.; Banegas-Font, I.; Iturrioz, X.; Rozenfeld, R.; Maigret, B.; Llorens-Cortes, C.
Identification of threonine 348 as a residue involved in aminopeptidase A substrate specificity
J. Biol. Chem.
284
10618-10626
2009
Mus musculus (P16406), Mus musculus
de Mota, N.; Iturrioz, X.; Claperon, C.; Bodineau, L.; Fassot, C.; Roques, B.P.; Palkovits, M.; Llorens-Cortes, C.
Human brain aminopeptidase A: biochemical properties and distribution in brain nuclei
J. Neurochem.
106
416-428
2008
Homo sapiens, Mus musculus
Ogawa, Y.; Kanai-Azuma, M.; Akimoto, Y.; Kawakami, H.; Yanoshita, R.
Exosome-like vesicles in Gloydius blomhoffii blomhoffii venom
Toxicon
51
984-993
2008
Gloydius blomhoffii
Kim, D.; San, B.; Moh, S.; Park, H.; Kim, D.; Lee, S.; Kim, K.
Structural basis for the substrate specificity of PepA from Streptococcus pneumoniae, a dodecameric tetrahedral protease
Biochem. Biophys. Res. Commun.
391
431-436
2010
Streptococcus pneumoniae (A0A0H2ZP50), Streptococcus pneumoniae
Asano, M.; Nakamura, N.; Kawai, M.; Miwa, T.; Nio, N.
Purification and characterization of an N-terminal acidic amino acid-specific aminopeptidase from soybean cotyledons (Glycine max)
Biosci. Biotechnol. Biochem.
74
113-118
2010
Glycine max
Blanco, L.; Sanz, B.; Perez, I.; Sanchez, C.E.; Candenas, M.L.; Pinto, F.M.; Gil, J.; Casis, L.; Lopez, J.I.; Larrinaga, G.
Altered glutamyl-aminopeptidase activity and expression in renal neoplasms
BMC Cancer
14
386
2014
Homo sapiens
Ramírez-Expósito, M.J.; Mayas-Torres, M.D.; Carrera-González, M.P.;, Jiménez-Pulido S.B.; Illán-Cabeza, N.A.; Sánchez-Sánchez, P.;, Hueso-Ureña, F.;, Martínez-Martos, J.M.; Moreno-Carretero, M.N.
Silver(I)/6-hydroxyiminolumazine compounds differently modify renin-angiotensin system-regulating aminopeptidases A and N in human neuroblastoma and glioma cells
J. Inorg. Biochem.
138
56-63
2014
Homo sapiens
Robinson, M.; Buchtmann, K.; Jenkins, C.; Tacchi, J.; Raymond, B.; To, J.; Chowdhury, P.; Woolley, L.; Labbate, M.; Turnbull, L.; Whitchurch, C.; Padula, M.; Djordjevic, S.
MHJ-0125 is an M42 glutamyl aminopeptidase that moonlights as a multifunctional adhesin on the surface of Mycoplasma hyopneumoniae
Open Biology
3
130017
2013
Mycoplasma hyopneumoniae (Q4AAK4), Mycoplasma hyopneumoniae, Mycoplasma hyopneumoniae ATCC 25934 (Q4AAK4)
Montoro-Molina, S.; Quesada, A.; Zafra-Ruiz, P.V.; OValle, F.; Vargas, F.; Del Carmen de Gracia, M.; Osuna, A.; Wangensteen, R.
Immunological detection of glutamyl aminopeptidase in urine samples from cisplatin treated rats
Proteomics Clin. Appl.
9
630-635
2015
Rattus norvegicus
Tamura, N.; Lottspeich, F.; Baumeister, W.; Tamura, T.
The role of tricorn protease and its aminopeptidase-interacting factors in cellular protein degradation
Cell
95
637-648
1998
Thermoplasma acidophilum (O93655)
Kyrieleis, O.; Goettig, P.; Kiefersauer, R.; Huber, R.; Brandstetter, H.
Crystal structures of the tricorn interacting factor F3 from Thermoplasma acidophilum, a zinc aminopeptidase in three different conformations
J. Mol. Biol.
349
787-800
2005
Thermoplasma acidophilum (O93655), Thermoplasma acidophilum
Morais, R.L.; Hilzendeger, A.M.; Visniauskas, B.; Todiras, M.; Alenina, N.; Mori, M.A.; Araujo, R.C.; Nakaie, C.R.; Chagas, J.R.; Carmona, A.K.; Bader, M.; Pesquero, J.B.
High aminopeptidase A activity contributes to blood pressure control in ob/ob mice by AT2 receptor-dependent mechanism
Am. J. Physiol. Heart Circ. Physiol.
312
H437-H445
2017
Mus musculus (P16406), Mus musculus, Mus musculus C57BL/6 (P16406)
Blanco, L.; Sanz, B.; Perez, I.; Sanchez, C.E.; Candenas, M.L.; Pinto, F.M.; Gil, J.; Casis, L.; Lopez, J.I.; Larrinaga, G.
Altered glutamyl-aminopeptidase activity and expression in renal neoplasms
BMC Cancer
14
386-394
2014
Homo sapiens (Q07075)
Wangensteen, R.; Segarra, A.B.; Ramirez-Sanchez, M.; Gasparo, M.D.; Dominguez, G.; Banegas, I.; Vargas, F.; Vives, F.; Prieto, I.
Influence of thyroid disorders on the kidney expression and plasma activity of aminopeptidase A
Endocr. Regul.
49
68-72
2015
Rattus norvegicus (P15684), Rattus norvegicus Wistar (P15684)
Ewert, J.; Glueck, C.; Strasdeit, H.; Fischer, L.; Stressler, T.
Influence of the metal ion on the enzyme activity and kinetics of PepA from Lactobacillus delbrueckii
Enzyme Microb. Technol.
110
69-78
2018
Lactobacillus delbrueckii subsp. lactis (F0HXE4), Lactobacillus delbrueckii subsp. lactis DSM 20072 (F0HXE4)
Nakamura, T.; Yamazato, M.; Ishida, A.; Ohya, Y.
Excess of aminopeptidase A in the brain elevates blood pressure via the angiotensin II type 1 and bradykinin B2 receptors without dipsogenic effect
Int. J. Hypertens.
2017
3967595
2017
Rattus norvegicus (P15684), Rattus norvegicus Wistar-Kyoto (P15684)
Stressler, T.; Ewert, J.; Merz, M.; Funk, J.; Claassen, W.; Lutz-Wahl, S.; Schmidt, H.; Kuhn, A.; Fischer, L.
A novel glutamyl (aspartyl)-specific aminopeptidase A from Lactobacillus delbrueckii with promising properties for application
PLoS ONE
11
e0152139
2016
Lactococcus lactis ssp. lactis, Lactobacillus delbrueckii subsp. lactis (F0HXE4), Lactobacillus delbrueckii subsp. lactis, Lactobacillus delbrueckii subsp. lactis DSM 20072 (F0HXE4), Lactococcus lactis ssp. lactis DSM 20481
Quesada, A.; Segarra, A.B.; Montoro-Molina, S.; de Gracia, M.D.; Osuna, A.; O'Valle, F.; Gomez-Guzman, M.; Vargas, F.; Wangensteen, R.
Glutamyl aminopeptidase in microvesicular and exosomal fractions of urine is related with renal dysfunction in cisplatin-treated rats
PLoS ONE
12
e0175462
2017
Rattus norvegicus (P50123), Rattus norvegicus Wistar (P50123)
Couvineau, P.; de Almeida, H.; Maigret, B.; Llorens-Cortes, C.; Iturrioz, X.
Involvement of arginine 878 together with Ca2+ in mouse aminopeptidase A substrate specificity for N-terminal acidic amino-acid residues
PLoS ONE
12
e0184237
2017
Mus musculus (P16406), Mus musculus
Stressler, T.; Tanzer, C.; Ewert, J.; Claassen, W.; Fischer, L.
Simple purification method for a recombinantly expressed native His-tag-free aminopeptidase A from Lactobacillus delbrueckii
Protein Expr. Purif.
131
7-15
2017
Lactobacillus delbrueckii subsp. lactis (F0HXE4), Lactobacillus delbrueckii subsp. lactis DSM 20072 (F0HXE4)
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