Reference on EC 3.4.11.6 - aminopeptidase B
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Sharma, A.; Padwal-Desai, S.R.; Ninjoor, V.
Intracellular hydrolases of Aspergillus parasiticus and Aspergillus flavus
Biochem. Biophys. Res. Commun.
159
464-471
1989
Aspergillus flavus, Aspergillus parasiticus
Mendz, G.L.; McCall, M.N.; Kuchel, P.W.
Characterization of leukocyte enzymes involved in the release of amino acids in incubated blood cell lysates
J. Biol. Chem.
264
2108-2117
1989
Homo sapiens
Schmidt, U.; Weller, D.; Holder, A.; Lieberknecht, A.
Total synthesis of OF4949-III, a natural inhibitor of aminopeptidase B from Ehrlich ascites carcinoma cells
Tetrahedron Lett.
29
3227-3230
1988
Mus musculus
-
Lauffart, B.; Mantle, D.
Rationalization of aminopeptidase activities in human skeletal muscle soluble extract
Biochim. Biophys. Acta
956
300-306
1988
Homo sapiens
Harbeson, S.L.; Rich, D.H.
Inhibition of arginine aminopeptidase by bestatin and arphamenine analogues. Evidence for a new mode of binding to aminopeptidases
Biochemistry
27
7301-7310
1988
Rattus norvegicus
Lauffart, B.; McDermott, J.; Jones, P.; Mantle, D.
Amino acid inhibition of aminopeptidases purified from human cerebral cortex
Biochem. Soc. Trans.
16
849-850
1988
Homo sapiens
-
Ishiura, S.; Yamamoto, T.; Yamamoto, M.; Nojima, M.; Aoyagi, T.; Sugita, H.
Human skeletal muscle contains two major aminopeptidases: an anion-activated aminopeptidase B and an aminopeptidase M-like enzyme
J. Biochem.
102
1023-1031
1987
Homo sapiens
Ocain, T.D.; Rich, D.H.
L-Lysinethiol: a subnanomolar inhibitor of aminopeptidase B
Biochem. Biophys. Res. Commun.
145
1038-1042
1987
Rattus norvegicus
Hiraoka, B.Y.
Immunochemical properties and intracellular localization of two molecular forms of arginine aminopeptidase in Streptococcus mitis ATCC 9811
Biochim. Biophys. Acta
841
166-172
1985
Streptococcus mitis
Blahovec, J.; Bartik, M.; Kasafirek, E.
Isolation and partial characterization of bovine liver aminopeptidase B
Collect. Czech. Chem. Commun.
50
1249-1257
1985
Bos taurus
-
Chan, S.A.T.; Toursarkissian, K.; Sweeny, J.P.; Jones, T.H.D.
Dipeptidyl-aminopeptidases and aminopeptidases in Dictyostelium discoideum
Biochem. Biophys. Res. Commun.
127
962-968
1985
Dictyostelium discoideum
Mantle, D.; Lauffart, B.; Pennington, R.J.T.
Purification and partial characterization of arginine aminopeptidases from human skeletal muscle
Biochem. Soc. Trans.
12
826-827
1984
Homo sapiens
-
Hiraoka, B.Y.; Fukasawa, K.; Harada, M.
Purification and characterization of two novel arginine aminopeptidases from Streptococcus mitis ATCC 9811
J. Biochem.
94
1201-1208
1983
Streptococcus mitis
Matsuzawa, T.; Hatsugai, M.
Effect of age on the activity of rat testicular arginine-aminopeptidase
Experientia
39
388-389
1983
Rattus norvegicus
Soederling, E.; Mkinen, K.K.
Modification of the Cl- -activated arginine aminopeptidases from rat liver and human erythrocytes: a comparative study
Arch. Biochem. Biophys.
220
11-21
1983
Homo sapiens, Rattus norvegicus
Soederling, E.
Substrate specificities of Cl- -activated arginine aminopeptidases from human and rat origin
Arch. Biochem. Biophys.
220
1-10
1983
Homo sapiens, Rattus norvegicus
Soederling, E.
Effect of Cl- on the function of the Cl- -activated arginine aminopeptidase purified from human erythrocytes
Arch. Biochem. Biophys.
216
105-115
1982
Homo sapiens
Kawata, S.; Takayama, S.; Ninimiya, K.; Makisumi, S.
Purification and some properties of porcine liver aminopeptidase B
J. Biochem.
88
1025-1032
1980
Sus scrofa
Kawata, S.; Takayama, S.; Ninomiya, K.; Makisumi, S.
Porcine liver aminopeptidase B. Substrate specificity and inhibition by amino acids
J. Biochem.
88
1601-1605
1980
Sus scrofa
Knuuttila, M.; Virtanen, K.; Soederling, E.; Maekinen, K.K.
A chloride-activated aminopeptidase in rat inflammatory exudate: properties and evidence of the origin of the enzyme
Biochem. Biophys. Res. Commun.
81
374-381
1978
Rattus norvegicus
Aoyagi, T.; Suda, H.; Nagai, M.; Ogawa, K.; Suzuki, J.; Takeuchi, T.; Umezawa, H.
Aminopeptidase activities on the surface of mammalian cells
Biochim. Biophys. Acta
452
131-143
1976
Canis lupus familiaris, Platyrrhini, Rattus norvegicus
Suda, H.; Aoyagi, T.; Takeuchi, T.; Umezawa, H.
Inhibition of aminopeptidase B and leucine aminopeptidase by bestatin and its stereoisomer
Arch. Biochem. Biophys.
177
196-200
1976
Rattus norvegicus
Mkinen, P.L.; Mkinen, K.K.
Fractionation and properties of aminopeptidase B during purification and storage
Int. J. Pept. Protein Res.
4
241-255
1972
Rattus norvegicus
Maekinen, K.K.
Evidence for the aggregation of aminopeptidase B during storage and breakdown of the aggregate by substrate and serum albumin
Biochim. Biophys. Acta
271
413-418
1972
Rattus norvegicus
Maekinen, K.K.; Maekinen, P.L.
Evidence on erythrocyte aminopeptidase B
Int. J. Pept. Protein Res.
111
41-47
1971
Rattus norvegicus
-
Maekinen, K.K.; Paunio, K.U.
Demonstration of aminopeptidase B in human periodontal tissues
Acta Chem. Scand.
24
1103-1104
1970
Homo sapiens
Maekinen, P.L.; Raekallio, J.; Maekinen, K.K.
On the localization of aminopeptidase B and separation of its two molecular forms by automated recycling chromatography
Acta Chem. Scand.
24
1101-1102
1970
Rattus norvegicus
Maekinen, K.K.; Hopsu-Havu, V.K.
The active centre of aminopeptidase B. I. The effects of various chemical reagents
Enzymologia
32
333-346
1967
Rattus norvegicus
Maekinen, K.K.; Hopsu-Havu, V.K.
The active centre of aminopeptidase B. II. Kinetic studies
Enzymologia
32
347-363
1967
Rattus norvegicus
Hopsu, V.K.; Maekinen, K.K.; Glenner, G.G.
Purification of a mammalian peptidase selective for N-terminal arginine and lysine residues: aminopeptidase B
Arch. Biochem. Biophys.
114
557-566
1966
Rattus norvegicus
Hopsu-Havu, V.K.; Maekinen, K.K.
A simplified method for purification of rat liver aminopeptidase B
Arch. Biochem. Biophys.
118
257-258
1967
Rattus norvegicus
-
Hopsu, V.K.; Maekinen, K.K.; Glenner, G.G.
Characterization of aminopeptidase B: substrate specificity and affector studies
Arch. Biochem. Biophys.
114
567-575
1966
Rattus norvegicus
McDonald, J.K.; Barrett, A.J.
Soluble arginyl aminopeptidase
Mammalian Proteases, Academic Press
2
48-55
1986
Homo sapiens, Rattus norvegicus, Sus scrofa
-
Cadel, S.; Pierotti, A.R.; Foulon, T.; Creminon, C.; Barre, N.; Segretain, D.; Cohen, P.
Aminopeptidase B in the rat testes: isolation, functional properties and cellular localization in the seminiferous tubules
Mol. Cell. Endocrinol.
110
149-160
1995
Rattus norvegicus
Cadel, S.; Foulon, T.; Viron, A.; Balogh, A.; Midol-Monnet, S.; Noel, N.; Cohen, P.
Aminopeptidase B from the rat testis is a bifunctional enzyme structurally related to leukotriene-A4 hydrolase
Proc. Natl. Acad. Sci. USA
94
2963-2968
1997
Rattus norvegicus (O09175)
Cook, M.; Adam, Z.
Purification and characterization of an arginyl peptidase from the chloroplast stroma of pea seedlings
Plant Physiol. Biochem.
35
163-168
1997
Pisum sativum
-
Toldra, F.; Falkous, G.; Flores, M.; Mantle, D.
Comparison of aminopeptidase inhibition by amino acids in human and porcine skeletal muscle tissues in vitro
Comp. Biochem. Physiol. B
115
445-450
1996
Homo sapiens, Sus scrofa
-
Fukasawa, K.M.; Fukasawa, K.; Kanai, M.; Fujii, S.; Harada, M.
Molecular cloning and expression of rat liver aminopeptidase B
J. Biol. Chem.
271
30731-30735
1996
Homo sapiens, Rattus norvegicus
Yamada, M.; Sukenaga, Y.; Fujii, H.; Abe, F.; Takeuchi, T.
Purification and characterization of a ubenimex (Bestatin)-sensitive aminopeptidase B-like enzyme from K562 human chronic myeloid leukemia cells
FEBS Lett.
342
53-56
1994
Homo sapiens
Belbacene, N.; Mari, B.; Rossi, B.; Auberger, P.
Characterization and purification of T lymphocyte aminopeptidase B: a putative marker of T cell activation
Eur. J. Immunol.
23
1948-1955
1993
Homo sapiens
Nagata, Y.; Mizutani, S.; Nomura, S.; Kurauchi, O.; Kasugai, M.; Tomoda, Y.
Purification and properties of human placental aminopeptidase B
Enzyme
45
165-173
1991
Homo sapiens
Floderus, E.; Linder, L.E.; Sund, M.S.
Characterization of membrane-associated arginine aminopeptidase in Streptococcus sanguis 903
Curr. Microbiol.
21
145-149
1990
Streptococcus sanguinis, Streptococcus sanguinis 903
-
Herranz, R.; Garcia-Lopez, M.T.; Perez, C.
Synergistic inhibition of aminopeptidase B by penicillamine or cysteine and metallic salts
Arch. Pharm.
324
239-241
1991
Mus musculus
Flores, M.; Aristoy, M.C.; Toldra, F.
Feedback inhibition of porcine muscle alanyl and arginyl aminopeptidases in cured meat products
J. Agric. Food Chem.
46
4982-4986
1998
Sus scrofa
Sanz, Y.; Toldra, F.
Purification and characterization of an arginine aminopeptidase from Lactobacillus sakei
Appl. Environ. Microbiol.
68
1980-1987
2002
Latilactobacillus sakei
Suzuki, H.; Kamatani, S.; Kumagai, H.
Purification and characterization of aminopeptidase B from Escherichia coli K-12
Biosci. Biotechnol. Biochem.
65
1549-1558
2001
Escherichia coli
Goldstein, J.M.; Nelson, D.; Kordula, T.; Mayo, J.A.; Travis, J.
Extracellular arginine aminopeptidase from Streptococcus gordonii FSS2
Infect. Immun.
70
836-843
2002
Streptococcus gordonii (Q938E9), Streptococcus gordonii, Streptococcus gordonii FSS2 (Q938E9), Streptococcus gordonii FSS2
Tanioka, T.; Hattori, A.; Masuda, S.; Nomura, Y.; Nakayama, H.; Mizutani, S.; Tsujimoto, M.
Human leukocyte-derived arginine aminopeptidase. The third member of the oxytocinase subfamily of aminopeptidases
J. Biol. Chem.
278
32275-32283
2003
Homo sapiens (Q6P179), Homo sapiens
Huston, A.L.; Methe, B.; Deming, J.W.
Purification, characterization, and sequencing of an extracellular cold-active aminopeptidase produced by marine psychrophile Colwellia psychrerythraea strain 34H
Appl. Environ. Microbiol.
70
3321-3328
2004
Colwellia psychrerythraea
Saitoh, Y.; Koizumi, K.; Minami, T.; Sekine, K.; Sakurai, H.; Saiki, I.
A derivative of aminopeptidase inhibitor (BE15) has a dual inhibitory effect of invasion and motility on tumor and endothelial cells
Biol. Pharm. Bull.
29
709-712
2006
Homo sapiens
Petrov, V.V.; Fagard, R.H.; Lijnen, P.J.
Arginine-aminopeptidase in rat cardiac fibroblastic cells participates in angiotensin peptide turnover
Cardiovasc. Res.
61
724-735
2004
Rattus norvegicus
Piesse, C.; Cadel, S.; Gouzy-Darmon, C.; Jeanny, J.C.; Carriere, V.; Goidin, D.; Jonet, L.; Gourdji, D.; Cohen, P.; Foulon, T.
Expression of aminopeptidase B in the developing and adult rat retina
Exp. Eye Res.
79
639-648
2004
Rattus norvegicus (O09175)
Berthonneau, J.; Rodier, M.H.; El Moudni, B.; Jacquemin, J.L.
Toxoplasma gondii: Purification and characterization of an immunogenic metallopeptidase
Exp. Parasitol.
95
158-162
2000
Toxoplasma gondii
Mercado-Flores, Y.; Noriega-Reyes, Y.; Ramirez-Zavala, B.; Hernandez-Rodriguez, C.; Villa-Tanaca, L.
Purification and characterization of aminopeptidase (pumAPE) from Ustilago maydis
FEMS Microbiol. Lett.
234
247-253
2004
Ustilago maydis
Fundoiano-Hershcovitz, Y.; Rabinovitch, L.; Shulami, S.; Reiland, V.; Shoham, G.; Shoham, Y.
The ywad gene from Bacillus subtilis encodes a double-zinc aminopeptidase
FEMS Microbiol. Lett.
243
157-163
2005
Bacillus subtilis (P25152), Bacillus subtilis
Foulon, T.; Cadel, S.; Piesse, C.; Cohen, P.
Aminopeptidase B
Handbook of Proteolytic Enzymes (Barrett, J. ; Rawlings, N. D. ; Woessner, J. F. , eds) Academic Press
1
328-332
2004
Homo sapiens, Mus musculus, Rattus norvegicus
-
Agirregoitia, N.; Laiz-Carrion, R.; Varona, A.; Rio, M.P.; Mancera, J.M.; Irazusta, J.
Distribution of peptidase activity in teleost and rat tissues
J. Comp. Physiol. B
175
433-444
2005
Oncorhynchus mykiss, Rattus norvegicus, Sparus aurata
Millership, J.J.; Chappell, C.; Okhuysen, P.C.; Snowden, K.F.
Characterization of aminopeptidase activity from three species of microsporidia: Encephalitozoon cuniculi, Encephalitozoon hellem, and Vittaforma corneae
J. Parasitol.
88
843-848
2002
Vittaforma corneae
Ohishi, K.; Yamamoto, T.; Tomofuji, T.; Tamaki, N.; Watanabe, T.
Isolation and characterization of aminopeptidase from Capnocytophaga granulosa ATCC 51502
Oral Microbiol. Immunol.
20
67-72
2005
Capnocytophaga granulosa
Gasparello-Clemente, E.; Casis, L.; Varona, A.; Gil, J.; Irazusta, J.; Silveira, P.F.
Aminopeptidases in visceral organs during alterations in body fluid volume and osmolality
Peptides
24
1367-1372
2003
Rattus norvegicus
Cadel, S.; Piesse, C.; Gouzy-Darmon, C.; Cohen, P.; Foulon, T.
Arginyl aminopeptidase
Proteases in Biology and Disease (Hooper, N. M. ; Lendeckel, U. ) Springer
2
113-126
2004
Bos taurus, Homo sapiens, Mus musculus, Rattus norvegicus
-
Bellemare, A.; Vernoux, N.; Morisset, D.; Bourbonnais, Y.
Human pre-elafin inhibits a Pseudomonas aeruginosa-secreted peptidase and prevents its proliferation in complex media
Antimicrob. Agents Chemother.
52
483-490
2008
Pseudomonas aeruginosa
Fukasawa, K.M.; Hirose, J.; Hata, T.; Ono, Y.
Aspartic acid 405 contributes to the substrate specificity of aminopeptidase B
Biochemistry
45
11425-11431
2006
Rattus norvegicus
Hirose, J.; Ohsaki, T.; Nishimoto, N.; Matuoka, S.; Hiromoto, T.; Yoshida, T.; Minoura, T.; Iwamoto, H.; Fukasawa, K.M.
Characterization of the metal-binding site in aminopeptidase B
Biol. Pharm. Bull.
29
2378-2382
2006
Rattus norvegicus
Pinyol, M.; Bea, S.; Pla, L.; Ribrag, V.; Bosq, J.; Rosenwald, A.; Campo, E.; Jares, P.
Inactivation of RB1 in mantle-cell lymphoma detected by nonsense-mediated mRNA decay pathway inhibition and microarray analysis
Blood
109
5422-5429
2007
Homo sapiens
Pham, V.L.; Cadel, M.S.; Gouzy-Darmon, C.; Hanquez, C.; Beinfeld, M.C.; Nicolas, P.; Etchebest, C.; Foulon, T.
Aminopeptidase B, a glucagon-processing enzyme: site directed mutagenesis of the Zn2+-binding motif and molecular modelling
BMC Biochem.
8
21
2007
Rattus norvegicus
Knotz, S.; Boersma, M.; Saborowski, R.
Microassays for a set of enzymes in individual small marine copepods
Comp. Biochem. Physiol. A
145
406-411
2006
Acartia clausii, Centropages typicus, Corycaeus anglicus, Paracalanus parvus, Temora longicornis
Bolumar, T.; Sanz, Y.; Aristoy, M.; Toldra, F.
Protease (PrA and PrB) and prolyl and arginyl aminopeptidase activities from Debaryomyces hansenii as a function of growth phase and nutrient sources
Int. J. Food Microbiol.
107
20-26
2006
Debaryomyces hansenii, Debaryomyces hansenii CECT 12487
Hwang, S.R.; ONeill, A.; Bark, S.; Foulon, T.; Hook, V.
Secretory vesicle aminopeptidase B related to neuropeptide processing: molecular identification and subcellular localization to enkephalin- and NPY-containing chromaffin granules
J. Neurochem.
100
1340-1350
2007
Rattus norvegicus, Bos taurus (A2T1U6), Bos taurus
Banegas, I.; Prieto, I.; Vives, F.; Alba, F.; de Gasparo, M.; Segarra, A.B.; Hermoso, F.; Duran, R.; Ramirez, M.
Brain aminopeptidases and hypertension
J. Renin Angiotensin Aldosterone Syst.
7
129-134
2006
Rattus norvegicus
Qu, H.Q.; Marchand, L.; Frechette, R.; Bacot, F.; Lu, Y.; Polychronakos, C.
No association of type 1 diabetes with a functional polymorphism of the LRAP gene
Mol. Immunol.
44
2135-2138
2007
Homo sapiens
Hui, M.; Hui, K.S.
A novel aminopeptidase with highest preference for lysine
Neurochem. Res.
31
95-102
2006
Rattus norvegicus
Hwang, S.R.; Hook, V.
Zinc regulation of aminopeptidase B involved in neuropeptide production
FEBS Lett.
582
2527-2531
2008
Rattus norvegicus
Bogra, P.; Singh, J.; Singh, H.
Immobilization of goat brain aminopeptidase B in calcium alginate beads
Biocatal. Biotransform.
27
96-101
2009
Capra aegagrus
-
Bogra, P.; Singh, J.; Singh, H.
Purification and characterization of aminopeptidase B from goat brain
Process Biochem.
44
776-780
2009
Capra aegagrus
-
Sakamoto, Y.; Suzuki, Y.; Iizuka, I.; Tateoka, C.; Roppongi, S.; Okada, H.; Nonaka, T.; Morikawa, Y.; Nakamura, K.; Ogasawara, W.; Tanaka, N.
Crystallization and preliminary X-ray crystallographic studies of dipeptidyl aminopeptidase BII from Pseudoxanthomonas mexicana WO24
Acta Crystallogr. Sect. F
70
221-224
2014
Pseudoxanthomonas mexicana (V5YM14), Pseudoxanthomonas mexicana WO24 (V5YM14), Pseudoxanthomonas mexicana WO24
Ogawa, Y.; Ohnishi, A.; Goto, Y.; Sakuma, Y.; Watanabe, J.; Hattori, A.; Tsujimoto, M.
Role of glutamine-169 in the substrate recognition of human aminopeptidase B
Biochim. Biophys. Acta
1840
1872-1881
2014
Homo sapiens
Cadel, S.; Darmon, C.; Pernier, J.; Herve, G.; Foulon, T.
The M1 family of vertebrate aminopeptidases: Role of evolutionarily conserved tyrosines in the enzymatic mechanism of aminopeptidase B
Biochimie
109
67-77
2015
Rattus norvegicus
Ye, M.; Wysocki, J.; Gonzalez-Pacheco, F.R.; Salem, M.; Evora, K.; Garcia-Halpin, L.; Poglitsch, M.; Schuster, M.; Batlle, D.
Murine recombinant angiotensin-converting enzyme 2: effect on angiotensin II-dependent hypertension and distinctive angiotensin-converting enzyme 2 inhibitor characteristics on rodent and human angiotensin-converting enzyme 2
Hypertension
60
730-740
2012
Homo sapiens, Mus musculus
Cadel, S.; Darmon, C.; Desert, A.; Mahbouli, M.; Piesse, C.; Ghelis, T.; Lafont, R.; Foulon, T.
The effects of curcumin, mangiferin, resveratrol and other natural plant products on aminopeptidase B activity
Biochem. Biophys. Res. Commun.
512
832-837
2019
Rattus norvegicus
Ohnishi, A.; Watanabe, J.; Ogawa, Y.; Goto, Y.; Hattori, A.; Tsujimoto, M.
Involvement of phenylalanine 297 in the construction of the substrate pocket of human aminopeptidase B
Biochemistry
54
6062-6070
2015
Homo sapiens (Q9H4A4), Homo sapiens
Zhang, F.; Wu, D.; Wang, G.; Hou, S.; Ou-Yang, P.; Huang, J.; Xu, X.
Synthesis and biological evaluation of novel 1,2,3-benzotriazin-4-one derivatives as leukotriene A4 hydrolase aminopeptidase inhibitors
Chin. Chem. Lett.
28
1044-1048
2017
Homo sapiens (P09960)
-
Lu, W.; Yao, X.; Ouyang, P.; Dong, N.; Wu, D.; Jiang, X.; Wu, Z.; Zhang, C.; Xu, Z.; Tang, Y.; Zou, S.; Liu, M.; Li, J.; Zeng, M.; Lin, P.; Cheng, F.; Huang, J.
Drug repurposing of histone deacetylase inhibitors that alleviate neutrophilic inflammation in acute lung injury and idiopathic pulmonary fibrosis via inhibiting leukotriene A4 hydrolase and blocking LTB4 biosynthesis
J. Med. Chem.
60
1817-1828
2017
Homo sapiens (P09960)
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