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Information on EC 3.2.2.B5 - 8-oxoguanine DNA glycosylase and Organism(s) Saccharolobus solfataricus and UniProt Accession Q97ZK2

for references in articles please use BRENDA:EC3.2.2.B5
preliminary BRENDA-supplied EC number
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EC Tree
     3 Hydrolases
         3.2 Glycosylases
             3.2.2 Hydrolysing N-glycosyl compounds
                3.2.2.B5 8-oxoguanine DNA glycosylase
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This record set is specific for:
Saccharolobus solfataricus
UNIPROT: Q97ZK2 not found.
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Word Map
The taxonomic range for the selected organisms is: Saccharolobus solfataricus
The enzyme appears in selected viruses and cellular organisms
Reaction Schemes
DNA containing 8-oxoguanine
+
=
DNA with an abasic site
+
Synonyms
8-oxoguanine dna glycosylase, tvg_rs00315, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
8-oxoguanine DNA glycosylase
bifunctional enzyme that catalyzes the excision of 8-oxoguanine by cleaving the N-glycosylic bond between the base and the deoxyribose moiety (glycosylase activity) and subsequently cleave the DNA backbone (lyase activity, EC 4.2.99.18)
SYSTEMATIC NAME
IUBMB Comments
DNA glycohydrolase [8-oxoguanine releasing]
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
hanging-drop vapor diffusion at 12°C
PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
K128Q
glycosylase-deficient mutant
PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Faucher, F.; Duclos, S.; Bandaru, V.; Wallace, S.S.; Doublie, S.
Crystal structures of two archaeal 8-oxoguanine DNA glycosylases provide structural insight into guanine/8-oxoguanine distinction
Structure
17
703-712
2009
Methanocaldococcus jannaschii (Q58134), Methanocaldococcus jannaschii DSM 2661 (Q58134), Saccharolobus solfataricus (Q97ZK2), Saccharolobus solfataricus, Saccharolobus solfataricus P2 (Q97ZK2)
Manually annotated by BRENDA team