Information on EC 3.2.2.13 - 1-methyladenosine nucleosidase

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The enzyme appears in viruses and cellular organisms

EC NUMBER
COMMENTARY hide
3.2.2.13
-
RECOMMENDED NAME
GeneOntology No.
1-methyladenosine nucleosidase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
1-methyladenosine + H2O = 1-methyladenine + D-ribose
show the reaction diagram
-
-
-
-
SYSTEMATIC NAME
IUBMB Comments
1-methyladenosine ribohydrolase
-
CAS REGISTRY NUMBER
COMMENTARY hide
37367-71-8
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
-
-
Manually annotated by BRENDA team
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
1-methyladenosine + H2O
1-methyladenine + D-ribose
show the reaction diagram
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
1-methyladenosine + H2O
1-methyladenine + D-ribose
show the reaction diagram
INHIBITORS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
1-Methylguanosine
-
-
1-methylinosine
-
-
iodoacetamide
-
-
o-Iodosobenzoate
-
-
p-chloromercuribenzoate
-
-
ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2-mercaptoethanol
-
10 fold activation
cysteine
-
10 fold activation
dithiothreitol
-
10 fold activation
homocysteine
-
10 fold activation
KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
6.65 - 7.15
1-methyladenosine
-
-
pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
6.2 - 9.5
-
half maximum activity
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
-
mature
Manually annotated by BRENDA team
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
96000
-
gel filtration
TEMPERATURE STABILITY
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
40
-
inactivation
STORAGE STABILITY
ORGANISM
UNIPROT
LITERATURE
25°C, 2 h, 10%
-
35°C, 2 h, 10%
-
40°C, 30 min, 21%
-
Purification/COMMENTARY
ORGANISM
UNIPROT
LITERATURE