Information on EC 3.2.1.92 - peptidoglycan beta-N-acetylmuramidase

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The expected taxonomic range for this enzyme is: Bacillus subtilis

EC NUMBER
COMMENTARY hide
3.2.1.92
-
RECOMMENDED NAME
GeneOntology No.
peptidoglycan beta-N-acetylmuramidase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
hydrolysis of terminal, non-reducing N-acetylmuramic residues
show the reaction diagram
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-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
hydrolysis of O-glycosyl bond
-
-
-
-
SYSTEMATIC NAME
IUBMB Comments
peptidoglycan beta-N-acetylmuramoylexohydrolase
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CAS REGISTRY NUMBER
COMMENTARY hide
52219-03-1
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
4-methylumbelliferyl-2-acetamido-3-O-(D-1-carboxyethyl)-2-deoxy-beta-D-glucose + H2O
4-methylumbelliferone + 2-acetamido-3-O-(D-1-carboxyethyl)-2-deoxy-beta-D-glucose
show the reaction diagram
O-2-acetamido-2-deoxy-beta-D-glucopyranosyl-(1-4)-2-acetamido-3-O-(D-1-carboxyethyl)-2-deoxy-D-glucose + H2O
2-acetamido-2-deoxy-beta-D-glucopyranose + 2-acetamido-3-O-(D-1-carboxyethyl)-2-deoxy-D-glucose
show the reaction diagram
O-[2-acetamido-3-O-(D-1-carboxyethyl)-2-deoxy-beta-D-glucopyranosyl]-(1-4)-2-acetamido-2-deoxy-D-glucose + H2O
2-acetamido-3-O-(D-1-carboxyethyl)-2-deoxy-beta-D-glucose + 2-acetamido-2-deoxy-D-glucose
show the reaction diagram
additional information
?
-
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
additional information
?
-
INHIBITORS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2-acetamido-2-deoxy-D-galactose
-
-
2-acetamido-2-deoxy-D-glucose
-
-
2-acetamido-2-deoxy-D-mannose
-
-
2-acetamido-3-O-(D-1-carboxyethyl)-2-deoxy-D-glucose
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MurAc, 1 mM, activity 76,9%
KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.19
4-Methylumbelliferyl-2-acetamido-3-O-(D-1-carboxyethyl)-2-deoxy-beta-D-glucose
-
-
0.65
O-[2-acetamido-3-O-(D-1-carboxyethyl)-2-deoxy-beta-D-glucopyranosyl]-(1-4)-2-acetamido-2-deoxy-D-glucose
-
-
SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
90000
-
estimated by SDS-PAGE, purified enzyme
pH STABILITY
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
8
-
most stable at
137009
Purification/COMMENTARY
ORGANISM
UNIPROT
LITERATURE