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Information on EC 3.2.1.33 - amylo-alpha-1,6-glucosidase and Organism(s) Equus caballus and UniProt Accession A8BQB4

for references in articles please use BRENDA:EC3.2.1.33
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EC Tree
IUBMB Comments
This enzyme hydrolyses an unsubstituted glucose unit linked by an alpha(1->6) bond to an alpha(1->4) glucose chain. The enzyme activity found in mammals and yeast is in a polypeptide chain containing two active centres. The other activity is similar to that of EC 2.4.1.25 (4-alpha-glucanotransferase), which acts on the glycogen phosphorylase limit dextrin chains to expose the single glucose residues, which the 6-alpha-glucosidase activity can then hydrolyse. Together, these two activities constitute the glycogen debranching system.
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This record set is specific for:
Equus caballus
UNIPROT: A8BQB4
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The taxonomic range for the selected organisms is: Equus caballus
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria, Archaea
Synonyms
amylo-1,6-glucosidase, debrancher enzyme, amylo-alpha-1,6-glucosidase, debrancher protein, amylo-alpha-1,6-glucosidase activity, amylo-1,6-glucosidase/4-alpha-glucanotransferase, dextrin 6-glucohydrolase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
amylo-1,6-glucosidase
part of the multifunctional glycogen debranching enzyme
1,4-glucan-4-glucosyltransferase/amylo-1,6-glucosidase
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4-alpha-glucano-transferase amylo-1,6-glucosidase
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alpha-(1,6)-glucosidase
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amylo-1,6-glucosidase
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amylo-1,6-glucosidase-oligo-1,4-1,4-transferase
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amylo-1,6-glucosidase/1,4-alpha-glucan 4-alpha-glucan 4-alpha-glycosyltransferase
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amylo-1,6-glucosidase/1,4-alpha-glucan:1,4-alpha-glucan 4-alpha-glycosyltransferase
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amylo-1,6-glucosidase/4-alpha-glucanotransferase
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amylo-1,6-glucosidase/oligo-1,4-1,4-glucantransferase
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amylopectin 1,6-glucosidase
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debrancher enzyme
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debrancher protein
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dextrin 6-alpha-D-glucosidase
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dextrin 6-alpha-glucosidase
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dextrin 6-glucanohydrolase
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dextrin 6-glucohydrolase
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dextrin-1,6-glucosidase
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dextrin:6-glucohydrolase
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glucosidase, amylo-1,6-
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glucosidase/transferase
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glycogen debranching enzyme
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glycogen phosphorylase limit dextrin debranching system
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indirect debranching enzyme
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oligo-alpha-1,4-glucan:alpha-1,4-glucan-4-glycosyltransferase-amylo-1,6-glucosidase
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transferase-glucosidase
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PATHWAY SOURCE
PATHWAYS
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SYSTEMATIC NAME
IUBMB Comments
glycogen phosphorylase-limit dextrin 6-alpha-glucohydrolase
This enzyme hydrolyses an unsubstituted glucose unit linked by an alpha(1->6) bond to an alpha(1->4) glucose chain. The enzyme activity found in mammals and yeast is in a polypeptide chain containing two active centres. The other activity is similar to that of EC 2.4.1.25 (4-alpha-glucanotransferase), which acts on the glycogen phosphorylase limit dextrin chains to expose the single glucose residues, which the 6-alpha-glucosidase activity can then hydrolyse. Together, these two activities constitute the glycogen debranching system.
CAS REGISTRY NUMBER
COMMENTARY hide
9012-47-9
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
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Uniprot
Manually annotated by BRENDA team
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
GDE_HORSE
1533
0
174666
Swiss-Prot
other Location (Reliability: 2)
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Herszberg, B.; Mata, X.; Giulotto, E.; Decaunes, P.; Piras, F.M.; Chowdhary, B.P.; Chaffaux, S.; Guerin, G.
Characterization of the equine glycogen debranching enzyme gene (AGL): Genomic and cDNA structure, localization, polymorphism and expression
Gene
404
1-9
2007
Equus caballus (A8BQB4)
Manually annotated by BRENDA team