Reference on EC 3.2.1.18 - exo-alpha-sialidase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Teufel, M.; Roggentin, P.; Schauer, R.
Properties of sialidase isolated from Actinomyces viscosus DSM 43798
Biol. Chem. Hoppe-Seyler
370
435-443
1989
Actinomyces viscosus
Schauer, R.; Wember, M.
Isolation and characterization of a sialidase from the starfish Asterias rubens
Biol. Chem. Hoppe-Seyler
370
183-190
1989
Asterias rubens, Homo sapiens
Lieser, M.; Harms, E.; Kern, H.; Bach, G.; Cantz, M.
Ganglioside GM3 sialidase activity in fibroblasts of normal individuals and of patients with sialidosis and mucolipidosis IV
Biochem. J.
260
69-74
1989
Homo sapiens
Harth, G.; Haidaris, C.G.; So, M.
Neuraminidase from Trypanosoma cruzi: Analysis of enhanced expression of the enzyme in infectious forms
Proc. Natl. Acad. Sci. USA
84
8320-8324
1987
Trypanosoma cruzi
Barnes, J.A.; Allan T.M.
Characterization of Sendai virus neuraminidase activity
Enzyme Microb. Technol.
6
553-558
1987
Murine respirovirus
-
Hiraiwa, M.; Uda, Y.; Nishizawa, M.; Miyatake, T.
Human placental sialidase: partial purification and characterization
J. Biochem.
101
1273-1279
1987
Homo sapiens
Bouwstra, J.B.; Deyl, C.M.; Vliegenthart, J.F.G.
Purification and kinetic properties of sialidase from Clostridium perfringens
Biol. Chem. Hoppe-Seyler
368
269-275
1987
Clostridium perfringens
Arora, D.J.S.; Gabriel, L.F.
Characterization of influenza virus neuraminidase with haemagglutinin activity and its comparison with that of viral neuraminidase
Biochim. Biophys. Acta
884
73-83
1986
unidentified influenza virus
Baricos, W.H.; Cortez-Schwartz, S.; Shah, S.V.
Renal neuraminidase: characterization in normal rat kidney and measurement in experimentally induced nephrotic syndrome
Biochem. J.
239
705-710
1986
Rattus norvegicus
Michalski, J.C.; Corfield, A.P.; Schauer, R.
Properties of human liver lysosomal sialidase
Biol. Chem. Hoppe-Seyler
367
715-722
1986
Homo sapiens
Miyagi, T.; Tsuiki, S.
Purification and characterization of cytosolic sialidase from rat liver
J. Biol. Chem.
260
6710-6716
1986
Rattus norvegicus
Hiraiwa, M.; Uda, Y.; Nishizawa, M.; Uda, Y.; Nakajima, T.; Miyatake, T.
Human placental sialidase: further purification and characterization
J. Biochem.
103
86-90
1988
Homo sapiens
Colman, P.M.; Ward, C.W.
Structure and diversity of influenza virus neuraminidase
Curr. Top. Microbiol. Immunol.
114
176-255
1985
unidentified influenza virus
-
Verheuen, F.W.; Palmeri, S.; Galjaard, H.
Purification and partial characterization of lysosomal neuraminidase from human placenta
Eur. J. Biochem.
162
63-67
1987
Homo sapiens
Miyagi, T.; Tsuiki, S.
Rat liver lysosomal sialidase: solubilization, substrate specificity and comparison with the cytosolic sialidase
Eur. J. Biochem.
141
75-81
1984
Rattus norvegicus
Schauer, R.; Nhle, U.
Sialidase (neuraminidase)
Methods Enzym. Anal. , 3rd Ed. (Bergmeyer, H. U. , ed. )
4
195-208
1984
Actinomyces viscosus, Clostridium perfringens
-
Schauer, R.; Wember, M.; Tschetsche, H.
Isolation and characterization of an oligosaccharide- and glycoprotein-specific sialidase from human leucocytes
Hoppe-Seyler's Z. Physiol. Chem.
365
419-426
1984
Homo sapiens
Eschenfelder, V.; Brossmer, R.; Wachter, M.
On the specificity of sialidase: synthesis and properties of N5-acetyl-beta-D-neuraminoylpeptides - AcNeu-Gly-OH, AcNeu-Glu-OH, AcNeu-Phe-OH - and the corresponding alpha-ketosides
Hoppe-Seyler's Z. Physiol. Chem.
364
1411-1417
1983
Vibrio cholerae serotype O1
Berg, J.O.; Lindqvist, L.; Andersson, G.; Nord, C.E.
Neuraminidase in Bacteroides fragilis
Appl. Environ. Microbiol.
46
75-80
1983
Bacteroides fragilis
von Nicolai, H.; Hammann, R.; Werner, H.; Zilliken, F.
Isolation and characterization of sialidase from Bacteroides fragilis
FEMS Microbiol. Lett.
17
217-220
1983
Bacteroides fragilis
-
Michalski, J.C.; Corfield, A.P.; Schauer, R.
Solubilization and affinity chromatography of a sialidase from human liver
Hoppe-Seyler's Z. Physiol. Chem.
363
1097-1102
1982
Homo sapiens
Verheijen, F.; Brossmer, R.; Galjaard, H.
Purification of acid beta-galactosidase and acid neuraminidase from bovine testis: evidence for an enzyme complex
Biochem. Biophys. Res. Commun.
108
868-875
1982
Bos taurus
Meyer, D.M.; Lemmonier, M.; Bourrillon, R.
Human liver neuraminidase
Biochem. Biophys. Res. Commun.
103
1302-1309
1981
Homo sapiens
Vertiev, Y.V.; Ezepchuk Y.V.
Purification and characterization of some enzymatic properties of neuraminidase from Corynebacterium ulcerans
Hoppe-Seyler's Z. Physiol. Chem.
362
1339-1344
1981
Corynebacterium ulcerans
Tabatabai, L.B.; Frank, G.H.
Neuraminidase from Pasteurella haemolytica
Curr. Microbiol.
5
203-206
1981
Mannheimia haemolytica
-
von Nicolai, H.; Esser, P.; Lauer, E.
Partial purification of neuraminidase from Bifidobacterim lactentis
Hoppe-Seyler's Z. Physiol. Chem.
362
153-162
1981
Bifidobacterium longum subsp. infantis
Leprat, R.; Michel-Briand, Y.
Extracellular neuraminidase production by a strain of Pseudomonas aeruginosa isolated from cystic fibrosis
Ann. Microbiol.
131
209-222
1980
Pseudomonas aeruginosa, Pseudomonas aeruginosa Mu 15
Cabezas, J.A.; Calvo, P.; Eid, P.; Martin, J.; Perez, N.; Reglero, A.; Hannoun, C.
Neuraminidase fro influenza virus A (H3N2)
Biochim. Biophys. Acta
616
228-238
1980
unidentified influenza virus, unidentified influenza virus A (H3N2)
Milligan, T.W.; Mattingly, S.J.; Straus, D.C.
Purification and partial characterization of neuraminidase from typ III group B Streptococci
J. Bacteriol.
144
164-172
1980
Streptococcus sp.
Wang, P.; Schafer, D.; Hohm C.E.; Tanenbaum, S.W.; Flashner, M.
Properties of Arthrobacter sialophilus neuraminidase
Glycoconjugate Res.
2
955-957
1977
Arthrobacter sialophilus
-
Schengrund, C.L.; Repman, M.A.; Nelson, J.T.
Distribution in spleen subcellular organelles of sialidase active towards natural sialoglycolipid and sialoglycoprotein substrates
Biochim. Biophys. Acta
568
377-385
1979
Bos taurus
Davis, L.; Baig, M.M.; Ayoub, E.M.
Properties of extracellular neuraminidase produced by group A Streptococcus
Infect. Immun.
24
780-786
1979
Streptococcus sp.
Thomas, G.H.; Reynolds, L.W.; Miller, C.S.
Characterization of neuraminidase activity of cultured human fibroblasts
Biochim. Biophys. Acta
568
39-48
1979
Homo sapiens
Wang, P.; Tanenbaum, S.W.; Flashner, M.
Purification and properties of Arthrobacter neurminidase
Biochim. Biophys. Acta
523
170-180
1978
Arthrobacter sp.
Uchida, Y.; Tsukada, Y.; Sugimori, T.
Distribution of neuraminidase in Arthrobacter and its purification by affinity chromatography
J. Biochem.
82
1425-1433
1977
Paenarthrobacter ureafaciens
Srivastava, P.N.; Abou-Issa, H.
Purification and properties of rabbit spermatozoal acrosomal neuraminidase
Biochem. J.
161
193-200
1977
Oryctolagus cuniculus
Ray, P.K.
Bacterial neuraminidase and altered immunological behavior of treated mammalian cells
Adv. Appl. Microbiol.
21
227-267
1977
Bos taurus, Oryctolagus cuniculus, Homo sapiens, Rattus norvegicus, Sus scrofa
Nees, S.; Veh, R.W.; Schauer, R.; Ehrlich, K.
Purification and characterization of neuraminidase from Clostridium perfringens
Hoppe-Seyler's Z. Physiol. Chem.
356
1027-1042
1975
Clostridium perfringens
Kiyohara, T.; Terao, T.; Shioiri-Nakano, K.; Osawa, T.
Purification and properties of a neuraminidase from Streptococcus K 6646
Arch. Biochem. Biophys.
164
575-582
1974
Streptococcus sp., Streptococcus sp. K6646
Preti, A.; Lombardo, A.; Cestaro, B.; Zambotti, S.; Tettamanti, G.
Studies on brain membrane-bound neuraminidase
Biochim. Biophys. Acta
350
406-414
1974
Bos taurus
Tallman J.F.; Brady, R.O.
The purification and properties of a mammalian neuraminidase (sialidase)
Biochim. Biophys. Acta
293
434-443
1973
Homo sapiens
Stahl, W.L.; O'Tool, R.D.
Pneumococcal neuraminidase: purification and properties
Biochim. Biophys. Acta
268
480-487
1972
Streptococcus pneumoniae
Tanenbaum, S.W.; Gulbinsky, J.; Katz, M.; Sun, S.C.
Separation, purification and some properties of pneumococcal neuraminidase isoenzymes
Biochim. Biophys. Acta
198
242-254
1970
Streptococcus pneumoniae
Tanenbaum, S.W.; Sun, S.C.
Some molecular properties of pneumococcal neuraminidase isoenzymes
Biochim. Biophys. Acta
229
824-828
1971
Clostridium perfringens, Streptococcus pneumoniae
Gatt, S.; Leibovitz, Z.
Neuraminidase from calf brain
Methods Enzymol.
14
149-152
1969
Bos taurus
-
Tuppy, H.; Palese, P.
Neuraminidase aus Schweinenieren
Hoppe-Seyler's Z. Physiol. Chem.
349
1169-1178
1968
Sus scrofa
Rafelson Jr, M.E.; Gold, S.; Priede, I.
Neuraminidase (sialidase) from influenza virus
Methods Enzymol.
8
677-680
1966
unidentified influenza virus
-
Cassidy, J.T.; Jourdian, G.W.; Roseman, S.
Sialidase from Clostridium perfringens
Methods Enzymol.
8
680-685
1966
Clostridium perfringens
-
De Martinez, N.R.; Olavarria, J.M.
Metabolism of sialic acids in toad oviduct
Biochim. Biophys. Acta
320
301-310
1973
Rhinella arenarum
Gottschalk, A.
Neuraminidase
The Enzymes, 2nd Ed (Boyer, P. D. , Lardy, H. , Myrbck, K. , eds. )
4
461-473
1960
unidentified influenza virus, Vibrio cholerae serotype O1
-
Chou, M.Y.; Li, S.C.; Kiso, M.; Hasegawa, A.; Li, Y.T.
Purification and characterization of sialidase L, a NeuAc alpha(2-3)Gal-specific sialidase
J. Biol. Chem.
269
18821-18826
1994
Macrobdella sp.
Waters, P.J.; Corfield, A.P.; Eisenthal, R.; Pennok, C.A.
Freeze-stable sialidase activity in human leucocytes: substrate specificity, inhibitor susceptibility, detergent requirements and subcellular localization
Biochem. J.
301
777-784
1994
Homo sapiens
-
Chen, X.G.; Nagai, T.; Yamada, H.
Sialidase in rabbit blood
Eur. J. Biochem.
221
655-664
1994
Oryctolagus cuniculus
Hiraiwa, M.; Saitoh, M.; Uda, Y.; Azuma, N.; Martin, B.M.; Kishimoto, Y.; O'Brien, J.S.
A sialidase complex from chicken liver: characterization of a multienzyme complex with beta-galactosidase and carboxypeptidase
Comp. Biochem. Physiol. B
4
541-546
1996
Gallus gallus
-
Terada, T.; Kitajima, K.; Inoue, S.; Wilson, J.C.; Norton, A.K.; Kong, D.C.M.; Thomson, R.J.; von Itzstein, M.; Inoue, Y.
Catalysis by a new sialidase, deaminoneuraminic acid residue-cleaving enzyme (KDNase Sm), initially forms a less stable alpha-anomer of 3-deoxy-D-glycero-D-galacto-nonulosonic acid and is strongly inhibited by the transition state analogue, 2-deoxy-2,3-didehydro-D-glycero-D-galacto-2-nonulopyranosonic acid, but not by 2-deoxy-2,3-didehydro-N-acetylneuraminic acid
J. Biol. Chem.
272
5452-5456
1997
Sphingobacterium multivorum
Amino, R.; Porto, R.M.; Chammas, R.; Egami, M.I.; Schenkman, S.
Identification and characterization of a sialidase released by the salivary gland of the hematophagous insect Triatoma infestans
J. Biol. Chem.
273
24575-24582
1998
Triatoma infestans
Miyagi, T.; Wada, T.; Iwamatsu, A.; Hata, K.; Yoshikawa, Y.; Tokuyama, S.; Sawada, M.
Molecular cloning and characterization of a plasma membrane-associated sialidase specific for gangliosides
J. Biol. Chem.
274
5004-5011
1999
Bos taurus (O97859), Bos taurus
Sagawa, J.; Miyagi, T.; Tsuiki, S.
Characterization of the major sialidases of various types of rat blood cells: their comparison with rat liver sialidases
J. Biochem.
107
452-456
1990
Rattus norvegicus
Hoyer, L.L.; Roggentin, P.; Schauer, R.; Vimr, E.R.
Purification and properties of cloned Salmonella typhimurium LT2 sialidase with virus-typical kinetic preference for sialyl alpha2-3 linkages
J. Biochem.
110
462-467
1991
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Engstler, M.; Reuter, G.; Schauer, R.
Purification and characterization of a novel sialidase found in procyclic culture forms of Trypanosoma brucei
Mol. Biochem. Parasitol.
54
21-30
1992
Trypanosoma brucei
Sastre, A.G.; Cobaleda, C.; Cabezas, J.A.; Villar, E.
On the inhibition mechanism of the sialidase activity from newcastle disease virus
Biol. Chem. Hoppe-Seyler
372
923-927
1991
Avian orthoavulavirus 1
Grobe, K.; Sartori, B.; Traving, C.; Schauer, R.; Roggentin, P.
Enzymatic and molecular properties of the Clostridium tertium sialidase
J. Biochem.
124
1101-1110
1998
Clostridium tertium
Roggentin, P.; Kleineidam, R.G.; Schauer, R.
Diversity in the properties of two sialidase isoenzymes produced by Clostridium perfringens spp.
Biol. Chem. Hoppe-Seyler
376
569-575
1995
Clostridium perfringens
Hata, K.; Wada, T.; Hasegawa, A.; Kiso, M.; Miyagi, T.
Purification and characterization of a membrane-associated ganglioside sialidase from bovine brain
J. Biochem.
123
899-905
1998
Bos taurus
Kobayashi, T.; Ito, M.; Ikeda, K.; Tannaka, K.; Saito, M.
Purification and characterization of a membrane-bound sialidase from pig liver
J. Biochem.
127
569-575
2000
Sus scrofa
Tanaka, H.; Ito, F.; Iwasaki, T.
Purification and characterization of sialidase from Bacteroides fragilis SBT3182
Biochem. Biophys. Res. Commun.
189
524-529
1992
Bacteroides fragilis, Bacteroides fragilis SBT3182
Hiraiwa, M.; Uda, Y.; Tsuji, S.; Miyatake, T.; Martin, B.M.; Tayama, M.; O. Brien, J.S.; Kishimoto, Y.
Human placental sialidase complex: characterization of the 60 kda protein that cross-reacts with anti-saposin antibodies
Biochem. Biophys. Res. Commun.
177
1211-1216
1991
Homo sapiens
Babal, P.; Pindak, F.F.
Purification and basic characteristics of sialidase from Tritrichomonas mobilensis
Folia Biol. (Praha)
41
319-330
1995
Tritrichomonas mobilensis
Byers, H.L.; Tarelli, E.; Homer, K.A.; Beighton, D.
Isolation and characterisation of sialidase from strain of Streptococcus oralis
J. Med. Microbiol.
49
235-244
2000
Streptococcus oralis
Martinez-Zorzano, V.S.; Feijoo, C.; de la Cadena, M.P.; Butron, M.; Fernandez-Briera, A.; Rodriguez-Berrocal, F.J.
Human colon sialidase: characterization and activity levels in normal mucosa and colonic adenocarcinoma
Enzyme Protein
48
282-290
1996
Homo sapiens
Nagaoka, M.; Saitoh, M.; Shiraishi, T.; Nagaoka, H.; Iriyama, N.; Furuhata, K.; Uda, Y.
Purification and characterization of sialidase from porcine liver
Biol. Pharm. Bull.
21
682-687
1998
Sus scrofa
Miyagi, T.; Hata, K.; Hasegawa, A.; Aoyagi, T.
Differential effect of various inhibitors on four types of rat sialidase
Glycoconj. J.
10
45-49
1993
Rattus norvegicus
Warner, T.G.; Chang, J.; Ferrari, J.; Harris, R.; McNerney, T.; Bennett, G.; Burnier, J.; Sliwkowski, M.B.
Isolation and properties of a soluble sialidase from the culture fluid of chinese hamster ovary cells
Glycobiology
3
455-463
1993
Cricetulus griseus
Heuermann, D.; Roggentin, P.; Kleineidam, R.G.; Schauer, R.
Purification and characterization of a sialidase from Clostridium chauvoei NC08596
Glycoconj. J.
8
95-101
1991
Clostridium chauvoei, Clostridium chauvoei NC08596
Roggentin, T.; Kleineidam, R.G.; schauer, R.; Roggentin, P.
Effects of site-specific mutations on the enzymatic properties of a sialidase from Clostridium perfringens
Glycoconj. J.
9
235-240
1992
Clostridium perfringens
Katinger, D.; Romanova, J.; Ferko, B.; Fekete, H.; Egorov, A.
Effect of a single mutation in neuraminidase on the properties of Influenza B virus isolates
Arch. Virol.
149
173-181
2004
influenza B virus (Q80A54), influenza B virus (Q80A58), influenza B virus
Inoue, S.; Lin, S.L.; Inoue, Y.; Groves, D.R.; Thomson, R.J.; von Itzstein, M.; Pavlova, N.V.; Li, S.C.; Li, Y.T.
A unique sialidase that cleaves the Neu5Gcalpha2->5-OglycolylNeu5Gc linkage: comparison of its specificity with that of three microbial sialidases toward four sialic acid dimers
Biochem. Biophys. Res. Commun.
280
104-109
2001
Clostridium perfringens, Crassostrea virginica, Paenarthrobacter ureafaciens, Vibrio cholerae serotype O1
Wang, P.; Zhang, J.; Bian, H.; Wu, P.; Kuvelkar, R.; Kung, T.T.; Crawley, Y.; Egan, R.W.; Billah, M.M.
Induction of lysosomal and plasma membrane-bound sialidases in human T-cells via T-cell receptor
Biochem. J.
380
425-433
2004
Homo sapiens, Mus musculus
Nagaoka, M.; Shiraishi, T.; Furuhata, K.; Uda, Y.
Effects of inorganic anions on the activation of acid sialidases
Biol. Pharm. Bull.
26
295-298
2003
Homo sapiens, Sus scrofa
Burg, M.; Muthing, J.
Characterization of cytosolic sialidase from Chinese hamster ovary cells: part I: cloning and expression of soluble sialidase in Escherichia coli
Carbohydr. Res.
330
335-346
2001
Cricetulus griseus
Muething, J.; Burg, M.
Characterization of cytosolic sialidase from Chinese hamster ovary cells: part II. Substrate specificity for gangliosides
Carbohydr. Res.
330
347-356
2001
Cricetulus griseus
Iriyama, N.; Takeuchi, N.; Shiraishi, T.; Izumi, K.; Sawada, M.T.; Takahashi, N.; Furuhata, K.; Ogura, H.; Uda, Y.
Enzymatic properties of sialidase from the ovary of the starfish, Asterina pectinifera
Comp. Biochem. Physiol. B
126
561-569
2000
Patiria pectinifera
Abrashev, I.; Dulguerova, G.
Neuraminidases (sialidases) from bacterial origin
Exp. Pathol. Parasitol.
4
35-40
2000
Arthrobacter sp., Clostridium chauvoei, Clostridium perfringens, Corynebacterium diphtheriae, Corynebacterium ulcerans, Erysipelothrix rhusiopathiae, Glutamicibacter nicotianae, Micromonospora viridifaciens, Paenarthrobacter ureafaciens, Paeniclostridium sordellii, Paeniclostridium sordellii G12, Pasteurella multocida, Streptococcus sp., Trichomonas vaginalis, Vibrio cholerae serotype O1
-
de Barros, J.F., Jr.; Sales Alviano, D.; da Silva, M.H.; Dutra Wigg, M.; Sales Alviano, C.; Schauer, R.; dos Santos Silva Couceiro, J.N.
Characterization of sialidase from an influenza A (H3N2) virus strain: kinetic parameters and substrate specificity
Intervirology
46
199-206
2003
influenza A virus
Chou, D.T.H.; Watson, J.N.; Scholte, A.A.; Borgford, T.J.; Bennet, A.J.
Effect of neutral pyridine leaving groups on the mechanisms of influenza type A viral sialidase-catalyzed and spontaneous hydrolysis reactions of alpha-D-N-acetylneuraminides
J. Am. Chem. Soc.
122
8357-8364
2000
influenza A virus
-
Mizan, S.; Henk, A.; Stallings, A.; Maier, M.; Lee, M.D.
Cloning and characterization of sialidases with 2-6' and 2-3' sialyl lactose specificity from Pasteurella multocida
J. Bacteriol.
182
6874-6883
2000
Pasteurella multocida (Q9EZV6), Pasteurella multocida (Q9EZV7), Pasteurella multocida
Johansson, B.E.; Brett, I.C.
Variation in the divalent cation requirements of influenza A virus N2 neuraminidases
J. Biochem.
134
345-352
2003
influenza A virus
Lukong, K.E.; Seyrantepe, V.; Landry, K.; Trudel, S.; Ahmad, A.; Gahl, W.A.; Lefrancois, S.; Morales, C.R.; Pshezhetsky, A.V.
Intracellular distribution of lysosomal sialidase is controlled by the internalization signal in its cytoplasmic tail
J. Biol. Chem.
276
46172-46181
2001
Homo sapiens
Papini, N.; Anastasia, L.; Tringali, C.; Croci, G.; Bresciani, R.; Yamaguchi, K.; Miyagi, T.; Preti, A.; Prinetti, A.; Prioni, S.; Sonnino, S.; Tettamanti, G.; Venerando, B.; Monti, E.
The plasma membrane-associated sialidase MmNEU3 modifies the ganglioside pattern of adjacent cells supporting its involvement in cell-to-cell interactions
J. Biol. Chem.
279
16989-16995
2004
Mus musculus
Ferreira, L.; Munoz-Barroso, I.; Marcos, F.; Shnyrov, V.L.; Villar, E.
Sialidase, receptor-binding and fusion-promotion activities of Newcastle disease virus haemagglutinin-neuraminidase glycoprotein: a mutational and kinetic study
J. Gen. Virol.
85
1981-1988
2004
Avian orthoavulavirus 1 (Q9Q2W5), Avian orthoavulavirus 1, Avian orthoavulavirus 1 Kansas (Q9Q2W5)
Wang, Z.M.; Tong, L.L.; Grant, D.; Cihlar, T.
Expression and characterization of soluble human parainfluenza virus type 1 hemagglutinin-neuraminidase glycoprotein
J. Virol. Methods
98
53-61
2001
Human respirovirus 1
Nok, A.J.; Rivera, W.
Characterization of sialidase from Entamoaeba hystolitica and possible pathogenic role in amebiasis
Parasitol. Res.
89
302-307
2003
Entamoeba histolytica
Amaya, M.F.; Watts, A.G.; Damager, I.; Wehenkel, A.; Nguyen, T.; Buschiazzo, A.; Paris, G.; Frasch, A.C.; Withers, S.G.; Alzari, P.M.
Structural insights into the catalytic mechanism of Trypanosoma cruzi trans-sialidase
Structure
12
775-784
2004
Trypanosoma cruzi
Nok, A.J.; Nzelibe, H.C.; Yako, S.K.
Trypanosoma evansi sialidase: surface localization, properties and hydrolysis of ghost red blood cells and brain cells-implications in trypanosomiasis
Z. Naturforsch. C
58
594-601
2003
Trypanosoma evansi
Newstead, S.; Chien, C.H.; Taylor, M.; Taylor, G.
Crystallization and atomic resolution X-ray diffraction of the catalytic domain of the large sialidase, nanI, from Clostridium perfringens
Acta Crystallogr. Sect. D
60
2063-2066
2004
Clostridium perfringens
Katinger, D.; Mochalova, L.; Chinarev, A.; Bovin, N.; Romanova, J.
Specificity of neuraminidase activity from influenza viruses isolated in different hosts tested with novel substrates
Arch. Virol.
149
2131-2140
2004
influenza A virus, influenza B virus
Hinou, H.; Kurogochi, M.; Shimizu, H.; Nishimura, S.
Characterization of Vibrio cholerae neuraminidase by a novel mechanism-based fluorescent labeling reagent
Biochemistry
44
11669-11675
2005
Vibrio cholerae serotype O1
Christensen, S.; Egebjerg, J.
Cloning, expression and characterization of a sialidase gene from Arthrobacter ureafaciens
Biotechnol. Appl. Biochem.
41
225-231
2005
Paenarthrobacter ureafaciens (Q5W7Q2), Paenarthrobacter ureafaciens
Buratai, L.B.; Nok, A.J.; Ibrahim, S.; Umar, I.A.; Esievo, K.A.
Characterization of sialidase from bloodstream forms of Trypanosoma vivax
Cell Biochem. Funct.
24
71-77
2006
Trypanosoma vivax, Trypanosoma vivax Agai, Trypanosoma vivax Agari
Monti, E.; Bassi, M.T.; Bresciani, R.; Civini, S.; Croci, G.L.; Papini, N.; Riboni, M.; Zanchetti, G.; Ballabio, A.; Preti, A.; Tettamanti, G.; Venerando, B.; Borsani, G.
Molecular cloning and characterization of NEU4, the fourth member of the human sialidase gene family
Genomics
83
445-453
2004
Homo sapiens
Abrashev, I.; Dulguerova, G.; Dolashka-Angelova, P.; Voelter, W.
Purification and characterization of a novel sialidase from a strain of Arthrobacter nicotianae
J. Biochem.
137
365-371
2005
Glutamicibacter nicotianae
Tringali, C.; Papini, N.; Fusi, P.; Croci, G.; Borsani, G.; Preti, A.; Tortora, P.; Tettamanti, G.; Venerando, B.; Monti, E.
Properties of recombinant human cytosolic sialidase HsNEU2: The enzyme hydrolyzes monomerically dispersed GM1 ganglioside molecules
J. Biol. Chem.
279
3169-3179
2004
Homo sapiens
Chavas, L.M.; Tringali, C.; Fusi, P.; Venerando, B.; Tettamanti, G.; Kato, R.; Monti, E.; Wakatsuki, S.
Crystal structure of the human cytosolic sialidase Neu2. Evidence for the dynamic nature of substrate recognition
J. Biol. Chem.
280
469-475
2005
Homo sapiens (Q9Y3R4), Homo sapiens
Watts, A.G.; Oppezzo, P.; Withers, S.G.; Alzari, P.M.; Buschiazzo, A.
Structural and kinetic analysis of two covalent sialosyl-enzyme intermediates on Trypanosoma rangeli sialidase
J. Biol. Chem.
281
4149-4155
2006
Trypanosoma rangeli (O44049), Trypanosoma rangeli
Ha, K.; Cho, S.; Kang, S.; Kim, Y.; Kim, J.; Kim, C.
Cloning of human liver cytosolic sialidase from genomic DNA using splicing by overlap extension and its characterization
J. Microbiol. Biotechnol.
15
722-727
2005
Homo sapiens
-
Ha, K.T.; Lee, Y.C.; Cho, S.H.; Kim, J.K.; Kim, C.H.
Molecular characterization of membrane type and ganglioside-specific sialidase (Neu3) expressed in E. coli
Mol. Cell
17
267-273
2004
Homo sapiens
da Silva, J.S.; Hasegawa, T.; Miyagi, T.; Dotti, C.G.; Abad-Rodriguez, J.
Asymmetric membrane ganglioside sialidase activity specifies axonal fate
Nat. Neurosci.
8
606-615
2005
Rattus norvegicus
Smith, B.J.; Huyton, T.; Joosten, R.P.; McKimm-Breschkin, J.L.; Zhang, J.G.; Luo, C.S.; Lou, M.Z.; Labrou, N.E.; Garrett, T.P.
Structure of a calcium-deficient form of influenza virus neuraminidase: implications for substrate binding
Acta Crystallogr. Sect. D
62
947-952
2006
unidentified influenza virus
Nakano, V.; Fontes Piazza, R.M.; Avila-Campos, M.J.
A rapid assay of the sialidase activity in species of the Bacteroides fragilis group by using peanut lectin hemagglutination
Anaerobe
12
238-241
2006
Bacteroides fragilis
Abed, Y.; Nehme, B.; Baz, M.; Boivin, G.
Activity of the neuraminidase inhibitor A-315675 against oseltamivir-resistant influenza neuraminidases of N1 and N2 subtypes
Antiviral Res.
77
163-166
2008
unidentified influenza virus
Tecle, T.; White, M.R.; Crouch, E.C.; Hartshorn, K.L.
Inhibition of influenza viral neuraminidase activity by collectins
Arch. Virol.
152
1731-1742
2007
influenza A virus
Yamaguchi, K.; Hata, K.; Wada, T.; Moriya, S.; Miyagi, T.
Epidermal growth factor-induced mobilization of a ganglioside-specific sialidase (NEU3) to membrane ruffles
Biochem. Biophys. Res. Commun.
346
484-490
2006
Homo sapiens (Q9UQ49), Homo sapiens
Moon, S.K.; Cho, S.H.; Kim, K.W.; Jeon, J.H.; Ko, J.H.; Kim, B.Y.; Kim, C.H.
Overexpression of membrane sialic acid-specific sialidase Neu3 inhibits matrix metalloproteinase-9 expression in vascular smooth muscle cells
Biochem. Biophys. Res. Commun.
356
542-547
2007
Homo sapiens (Q9UQ49)
Watson, J.N.; Indurugalla, D.; Cheng, L.L.; Narine, A.A.; Bennet, A.J.
The hydrolase and transferase activity of an inverting mutant sialidase using non-natural beta-sialoside substrates
Biochemistry
45
13264-13275
2006
Micromonospora viridifaciens (Q02834), Micromonospora viridifaciens
Neres, J.; Bonnet, P.; Edwards, P.N.; Kotian, P.L.; Buschiazzo, A.; Alzari, P.M.; Bryce, R.A.; Douglas, K.T.
Benzoic acid and pyridine derivatives as inhibitors of Trypanosoma cruzi trans-sialidase
Bioorg. Med. Chem.
15
2106-2119
2007
Trypanosoma cruzi
Agusti, R.; Giorgi, M.E.; Mendoza, V.M.; Gallo-Rodriguez, C.; de Lederkremer, R.M.
Comparative rates of sialylation by recombinant trans-sialidase and inhibitor properties of synthetic oligosaccharides from Trypanosoma cruzi mucins-containing galactofuranose and galactopyranose
Bioorg. Med. Chem.
15
2611-2616
2007
Trypanosoma cruzi
Magesh, S.; Moriya, S.; Suzuki, T.; Miyagi, T.; Ishida, H.; Kiso, M.
Design, synthesis, and biological evaluation of human sialidase inhibitors. Part 1: selective inhibitors of lysosomal sialidase (NEU1)
Bioorg. Med. Chem. Lett.
18
532-537
2008
Homo sapiens (Q99519), Homo sapiens
Aksenov, D.V.; Kaplun, V.V.; Tertov, V.V.; Sobenin, I.A.; Orekhov, A.N.
Effect of plant extracts on trans-sialidase activity in human blood plasma
Bull. Exp. Biol. Med.
143
46-50
2007
Homo sapiens
Blume, A.; Neubacher, B.; Thiem, J.; Peters, T.
Donor substrate binding to trans-sialidase of Trypanosoma cruzi as studied by STD NMR
Carbohydr. Res.
342
1904-1909
2007
Trypanosoma cruzi
Useh, N.M.; Ajanusi, J.O.; Esievo, K.A.; Nok, A.J.
Characterization of a sialidase (neuraminidase) isolated from Clostridium chauvoei (Jakari strain)
Cell Biochem. Funct.
24
347-352
2006
Clostridium chauvoei, Clostridium chauvoei Jakari
Takada, K.; Hamada, T.; Hirota, H.; Nakao, Y.; Matsunaga, S.; van Soest, R.W.; Fusetani, N.
Asteropine A, a sialidase-inhibiting conotoxin-like peptide from the marine sponge Asteropus simplex
Chem. Biol.
13
569-574
2006
Clostridium perfringens, Salmonella enterica subsp. enterica serovar Typhimurium, influenza A virus, Vibrio cholerae serotype O1
Chokhawala, H.A.; Yu, H.; Chen, X.
High-throughput substrate specificity studies of sialidases by using chemoenzymatically synthesized sialoside libraries
ChemBioChem
8
194-201
2007
Clostridium perfringens, Paenarthrobacter ureafaciens, Salmonella enterica subsp. enterica serovar Typhimurium, Streptococcus pneumoniae, Streptococcus sp.
Hasegawa, T.; Sugeno, N.; Takeda, A.; Matsuzaki-Kobayashi, M.; Kikuchi, A.; Furukawa, K.; Miyagi, T.; Itoyama, Y.
Role of Neu4L sialidase and its substrate ganglioside GD3 in neuronal apoptosis induced by catechol metabolites
FEBS Lett.
581
406-412
2007
Homo sapiens
Burnaugh, A.M.; Frantz, L.J.; King, S.J.
Growth of Streptococcus pneumoniae on human glycoconjugates is dependent upon the sequential activity of bacterial exoglycosidases
J. Bacteriol.
190
221-230
2008
Streptococcus pneumoniae, Streptococcus pneumoniae (Q54727)
Richard, M.; Deleage, C.; Barthelemy, M.; Lin, Y.P.; Hay, A.; Lina, B.; Ferraris, O.
Impact of influenza A virus neuraminidase mutations on the stability, activity, and sensibility of the neuraminidase to neuraminidase inhibitors
J. Clin. Virol.
41
20-24
2008
influenza A virus
Nan, X.; Carubelli, I.; Stamatos, N.M.
Sialidase expression in activated human T lymphocytes influences production of IFN-gamma
J. Leukoc. Biol.
81
284-296
2007
Homo sapiens (Q99519), Homo sapiens (Q9UQ49), Homo sapiens
Magesh, S.; Suzuki, T.; Miyagi, T.; Ishida, H.; Kiso, M.
Homology modeling of human sialidase enzymes NEU1, NEU3 and NEU4 based on the crystal structure of NEU2: hints for the design of selective NEU3 inhibitors
J. Mol. Graph. Model.
25
196-207
2006
Homo sapiens (Q8WWR8), Homo sapiens (Q9UQ49), Homo sapiens (Q9Y3R4), Homo sapiens
Yoshizumi, S.; Suzuki, S.; Hirai, M.; Hinokio, Y.; Yamada, T.; Yamada, T.; Tsunoda, U.; Aburatani, H.; Yamaguchi, K.; Miyagi, T.; Oka, Y.
Increased hepatic expression of ganglioside-specific sialidase, NEU3, improves insulin sensitivity and glucose tolerance in mice
Metab. Clin. Exp.
56
420-429
2007
Homo sapiens (Q9UQ49)
Zhu, X.; Xu, X.; Wilson, I.A.
Structure determination of the 1918 H1N1 neuraminidase from a crystal with lattice-translocation defects
Acta Crystallogr. Sect. D
D64
843-850
2008
unidentified influenza virus
Xu, G.; Li, X.; Andrew, P.W.; Taylor, G.L.
Structure of the catalytic domain of Streptococcus pneumoniae sialidase NanA
Acta Crystallogr. Sect. F
64
772-775
2008
Streptococcus pneumoniae (P62575), Streptococcus pneumoniae
Hinek, A.; Bodnaruk, T.D.; Bunda, S.; Wang, Y.; Liu, K.
Neuraminidase-1, a subunit of the cell surface elastin receptor, desialylates and functionally inactivates adjacent receptors interacting with the mitogenic growth factors PDGF-BB and IGF-2
Am. J. Pathol.
173
1042-1056
2008
Clostridium perfringens, Homo sapiens
Starcher, B.; dAzzo, A.; Keller, P.W.; Rao, G.K.; Nadarajah, D.; Hinek, A.
Neuraminidase-1 is required for the normal assembly of elastic fibers
Am. J. Physiol. Lung Cell Mol. Physiol.
295
L637-L647
2008
Mus musculus
Fanzani, A.; Giuliani, R.; Colombo, F.; Rossi, S.; Stoppani, E.; Martinet, W.; Preti, A.; Marchesini, S.
The enzymatic activity of sialidase Neu2 is inversely regulated during in vitro myoblast hypertrophy and atrophy
Biochem. Biophys. Res. Commun.
370
376-381
2008
Rattus norvegicus
Wu, Z.L.; Ethen, C.; Hickey, G.E.; Jiang, W.
Active 1918 pandemic flu viral neuraminidase has distinct N-glycan profile and is resistant to trypsin digestion
Biochem. Biophys. Res. Commun.
379
749-753
2009
influenza A virus (Q9IGQ6), influenza A virus A/South Carolina/1/1918 H1N1 (Q9IGQ6)
Kuroiwa, A.; Hisatsune, A.; Isohama, Y.; Katsuki, H.
Bacterial neuraminidase increases IL-8 production in lung epithelial cells via NF-kappaB-dependent pathway
Biochem. Biophys. Res. Commun.
379
754-759
2009
Clostridium perfringens
Damager, I.; Buchini, S.; Amaya, M.F.; Buschiazzo, A.; Alzari, P.; Frasch, A.C.; Watts, A.; Withers, S.G.
Kinetic and mechanistic analysis of Trypanosoma cruzi trans-sialidase reveals a classical ping-pong mechanism with acid/base catalysis
Biochemistry
47
3507-3512
2008
Trypanosoma cruzi
Demir, O.; Roitberg, A.
Modulation of catalytic function by differential plasticity of an active site: case study of Trypanosoma cruzi trans-sialidase and Trypanosoma rangeli sialidase
Biochemistry
48
3398-3406
2009
Trypanosoma cruzi, Trypanosoma rangeli (O44049), Trypanosoma rangeli
Jin, U.H.; Ha, K.T.; Kim, K.W.; Chang, Y.C.; Lee, Y.C.; Ko, J.H.; Kim, C.H.
Membrane type sialidase inhibits the megakaryocytic differentiation of human leukemia K562 cells
Biochim. Biophys. Acta
1780
757-763
2008
Homo sapiens
Krueger, A.C.; Xu, Y.; Kati, W.M.; Kempf, D.J.; Maring, C.J.; McDaniel, K.F.; Molla, A.; Montgomery, D.; Kohlbrenner, W.E.
Synthesis of potent pyrrolidine influenza neuraminidase inhibitors
Bioorg. Med. Chem. Lett.
18
1692-1695
2008
influenza A virus, influenza B virus, influenza B virus B/Memphis/3/89, influenza A virus A/N1/PR/8/34
Ryu, Y.B.; Curtis-Long, M.J.; Kim, J.H.; Jeong, S.H.; Yang, M.S.; Lee, K.W.; Lee, W.S.; Park, K.H.
Pterocarpans and flavanones from Sophora flavescens displaying potent neuraminidase inhibition
Bioorg. Med. Chem. Lett.
18
6046-6049
2008
Clostridium perfringens
Neres, J.; Brewer, M.L.; Ratier, L.; Botti, H.; Buschiazzo, A.; Edwards, P.N.; Mortenson, P.N.; Charlton, M.H.; Alzari, P.M.; Frasch, A.C.; Bryce, R.A.; Douglas, K.T.
Discovery of novel inhibitors of Trypanosoma cruzi trans-sialidase from in silico screening
Bioorg. Med. Chem. Lett.
19
589-596
2009
Trypanosoma cruzi
Zhang, J.; Wang, Q.; Fang, H.; Xu, W.; Liu, A.; Du, G.
Design, synthesis, inhibitory activity, and SAR studies of hydrophobic p-aminosalicylic acid derivatives as neuraminidase inhibitors
Bioorg. Med. Chem.
16
3839-3847
2008
influenza A virus
Liu, A.L.; Wang, H.D.; Lee, S.M.; Wang, Y.T.; Du, G.H.
Structure-activity relationship of flavonoids as influenza virus neuraminidase inhibitors and their in vitro anti-viral activities
Bioorg. Med. Chem.
16
7141-7147
2008
influenza A virus, influenza B virus, influenza A virus A/Jinan/15/90, influenza A virus A/PR/8/34, influenza B virus B/Jiangsu/10/2003
Ryu, Y.B.; Curtis-Long, M.J.; Lee, J.W.; Kim, J.H.; Kim, J.Y.; Kang, K.Y.; Lee, W.S.; Park, K.H.
Characteristic of neuraminidase inhibitory xanthones from Cudrania tricuspidata
Bioorg. Med. Chem.
17
2744-2750
2009
Clostridium perfringens (Q59310)
Mitrasinovic, P.M.
On the structure-based design of novel inhibitors of H5N1 influenza A virus neuraminidase (NA)
Biophys. Chem.
140
35-38
2009
influenza A virus
Proshin, S.N.; Kaminskaya, E.V.; Lebedev, A.A.; Shabanov, P.D.
Cells of rhabdomyosarcoma PA-23 tumor clones with high and low metastatic potential differ by activity of lysosomal sialidase
Bull. Exp. Biol. Med.
145
355-357
2008
Rattus norvegicus
Shiozaki, K.; Yamaguchi, K.; Sato, I.; Miyagi, T.
Plasma membrane-associated sialidase (NEU3) promotes formation of colonic aberrant crypt foci in azoxymethane-treated transgenic mice
Cancer Sci.
100
588-594
2009
Homo sapiens
Piagnerelli, M.; Boudjeltia, K.Z.; Rapotec, A.; Richard, T.; Brohee, D.; Babar, S.; Bouckaert, V.; Simon, A.C.; Toko, J.P.; Walravens, T.; Vincent, J.L.; Vanhaeverbeek, M.
Neuraminidase alters red blood cells in sepsis
Crit. Care Med.
37
1244-1250
2009
Clostridium perfringens, Homo sapiens
Yogalingam, G.; Bonten, E.J.; van de Vlekkert, D.; Hu, H.; Moshiach, S.; Connell, S.A.; dAzzo, A.
Neuraminidase 1 is a negative regulator of lysosomal exocytosis
Dev. Cell
15
74-86
2008
Mus musculus (O35657), Homo sapiens (Q99519), Homo sapiens
Shtyrya, Y.; Mochalova, L.; Voznova, G.; Rudneva, I.; Shilov, A.; Kaverin, N.; Bovin, N.
Adjustment of receptor-binding and neuraminidase substrate specificities in avian-human reassortant influenza viruses
Glycoconj. J.
26
99-109
2009
unidentified influenza virus
Anastasia, L.; Papini, N.; Colazzo, F.; Palazzolo, G.; Tringali, C.; Dileo, L.; Piccoli, M.; Conforti, E.; Sitzia, C.; Monti, E.; Sampaolesi, M.; Tettamanti, G.; Venerando, B.
NEU3 sialidase strictly modulates GM3 levels in skeletal myoblasts C2C12 thus favoring their differentiation and protecting them from apoptosis
J. Biol. Chem.
283
36265-36271
2008
Mus musculus
Newstead, S.L.; Potter, J.A.; Wilson, J.C.; Xu, G.; Chien, C.H.; Watts, A.G.; Withers, S.G.; Taylor, G.L.
The structure of Clostridium perfringens NanI sialidase and its catalytic intermediates
J. Biol. Chem.
283
9080-9088
2008
Clostridium perfringens (Q59310), Clostridium perfringens
Connaris, H.; Crocker, P.R.; Taylor, G.L.
Enhancing the receptor affinity of the sialic acid-binding domain of Vibrio cholerae sialidase through multivalency
J. Biol. Chem.
284
7339-7351
2009
Vibrio cholerae (P0C6E9), Vibrio cholerae
Garcia-Sosa, A.T.; Sild, S.; Maran, U.
Design of multi-binding-site inhibitors, ligand efficiency, and consensus screening of avian influenza H5N1 wild-type neuraminidase and of the oseltamivir-resistant H274Y variant
J. Chem. Inf. Model.
48
2074-2080
2008
influenza A virus
Abed, Y.; Baz, M.; Boivin, G.
A novel neuraminidase deletion mutation conferring resistance to oseltamivir in clinical influenza A/H3N2 virus
J. Infect. Dis.
199
180-183
2009
influenza A virus
Cheng, L.S.; Amaro, R.E.; Xu, D.; Li, W.W.; Arzberger, P.W.; McCammon, J.A.
Ensemble-based virtual screening reveals potential novel antiviral compounds for avian influenza neuraminidase
J. Med. Chem.
51
3878-3894
2008
unidentified influenza virus, unidentified influenza virus H5N1
Yongkiettrakul, S.; Boonyapakron, K.; Jongkaewwattana, A.; Wanitchang, A.; Leartsakulpanich, U.; Chitnumsub, P.; Eurwilaichitr, L.; Yuthavong, Y.
Avian influenza A/H5N1 neuraminidase expressed in yeast with a functional head domain
J. Virol. Methods
156
44-51
2009
unidentified influenza virus
Alymova, I.V.; Taylor, G.; Mishin, V.P.; Watanabe, M.; Murti, K.G.; Boyd, K.; Chand, P.; Babu, Y.S.; Portner, A.
Loss of the N-linked glycan at residue 173 of human parainfluenza virus type 1 hemagglutinin-neuraminidase exposes a second receptor-binding site
J. Virol.
82
8400-8410
2008
Human respirovirus 3
Yano, T.; Nobusawa, E.; Nagy, A.; Nakajima, S.; Nakajima, K.
Effects of single-point amino acid substitutions on the structure and function neuraminidase proteins in influenza A virus
Microbiol. Immunol.
52
216-223
2008
influenza A virus, influenza A virus A/tokyo/3/67
Gadhoum, S.Z.; Sackstein, R.
CD15 expression in human myeloid cell differentiation is regulated by sialidase activity
Nat. Chem. Biol.
4
751-757
2008
Homo sapiens
Collins, P.J.; Haire, L.F.; Lin, Y.P.; Liu, J.; Russell, R.J.; Walker, P.A.; Skehel, J.J.; Martin, S.R.; Hay, A.J.; Gamblin, S.J.
Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants
Nature
453
1258-1261
2008
unidentified influenza virus, unidentified influenza virus H5N1
Frank, J.E.; Thompson, V.P.; Brown, M.P.; Sandy, J.D.
Removal of O-linked and N-linked oligosaccharides is required for optimum detection of NITEGE neoepitope on ADAMTS4-digested fetal aggrecans: implications for specific N-linked glycan-dependent aggrecanolysis at Glu373-Ala374
Osteoarthritis Cartilage
17
777-781
2008
Clostridium perfringens (P10481)
Malaisree, M.; Rungrotmongkol, T.; Decha, P.; Intharathep, P.; Aruksakunwong, O.; Hannongbua, S.
Understanding of known drug-target interactions in the catalytic pocket of neuraminidase subtype N1
Proteins
71
1908-1918
2008
unidentified influenza virus
Fontanella, G.H.; De Vusser, K.; Laroy, W.; Daurelio, L.; Nocito, A.L.; Revelli, S.; Contreras, R.
Immunization with an engineered mutant trans-sialidase highly protects mice from experimental Trypanosoma cruzi infection: a vaccine candidate
Vaccine
26
2322-2334
2008
Trypanosoma cruzi
Pavlova, S.P.; Veits, J.; Keil, G.M.; Mettenleiter, T.C.; Fuchs, W.
Protection of chickens against H5N1 highly pathogenic avian influenza virus infection by live vaccination with infectious laryngotracheitis virus recombinants expressing H5 hemagglutinin and N1 neuraminidase
Vaccine
27
773-785
2009
unidentified influenza virus, unidentified influenza virus H5N1
Uchihara, T.; Ohashi, K.; Kitagawa, M.; Kurata, M.; Nakamura, A.; Hirokawa, K.; Kasuga, T.; Kobayashi, T.
Sialidosis type I carrying V217M/G243R mutations in lysosomal sialidase: an autopsy study demonstrating terminal sialic acid in lysosomal lamellar inclusions and cerebellar dysplasia
Acta Neuropathol.
119
135-145
2010
Homo sapiens
Hsiao, Y.S.; Parker, D.; Ratner, A.J.; Prince, A.; Tong, L.
Crystal structures of respiratory pathogen neuraminidases
Biochem. Biophys. Res. Commun.
380
467-471
2009
Streptococcus pneumoniae, Pseudomonas aeruginosa
DUrsi, P.; Chiappori, F.; Merelli, I.; Cozzi, P.; Rovida, E.; Milanesi, L.
Virtual screening pipeline and ligand modelling for H5N1 neuraminidase
Biochem. Biophys. Res. Commun.
383
445-449
2009
influenza A virus, influenza A virus N1
Wang, S.Q.; Du, Q.S.; Huang, R.B.; Zhang, D.W.; Chou, K.C.
Insights from investigating the interaction of oseltamivir (Tamiflu) with neuraminidase of the 2009 H1N1 swine flu virus
Biochem. Biophys. Res. Commun.
386
432-436
2009
swine influenza virus, swine influenza virus 2009 H1N1
Ryu, Y.B.; Kim, J.H.; Park, S.J.; Chang, J.S.; Rho, M.C.; Bae, K.H.; Park, K.H.; Lee, W.S.
Inhibition of neuraminidase activity by polyphenol compounds isolated from the roots of Glycyrrhiza uralensis
Bioorg. Med. Chem. Lett.
20
971-974
2010
unidentified influenza virus
Magesh, S.; Savita, V.; Moriya, S.; Suzuki, T.; Miyagi, T.; Ishida, H.; Kiso, M.
Human sialidase inhibitors: design, synthesis, and biological evaluation of 4-acetamido-5-acylamido-2-fluoro benzoic acids
Bioorg. Med. Chem.
17
4595-4603
2009
Homo sapiens (Q8WWR8), Homo sapiens (Q99519), Homo sapiens (Q9UQ49), Homo sapiens (Q9Y3R4), Homo sapiens
Arioka, S.; Sakagami, M.; Uematsu, R.; Yamaguchi, H.; Togame, H.; Takemoto, H.; Hinou, H.; Nishimura, S.
Potent inhibitor scaffold against Trypanosoma cruzi trans-sialidase
Bioorg. Med. Chem.
18
1633-1640
2010
Homo sapiens, Trypanosoma cruzi
Carvalho, I.; Andrade, P.; Campo, V.L.; Guedes, P.M.; Sesti-Costa, R.; Silva, J.S.; Schenkman, S.; Dedola, S.; Hill, L.; Rejzek, M.; Nepogodiev, S.A.; Field, R.A.
Click chemistry synthesis of a library of 1,2,3-triazole-substituted galactose derivatives and their evaluation against Trypanosoma cruzi and its cell surface trans-sialidase
Bioorg. Med. Chem.
18
2412-2427
2010
Trypanosoma cruzi, Trypanosoma cruzi Y
Nguyen, P.H.; Nguyen, T.N.; Kang, K.W.; Ndinteh, D.T.; Mbafor, J.T.; Kim, Y.R.; Oh, W.K.
Prenylated pterocarpans as bacterial neuraminidase inhibitors
Bioorg. Med. Chem.
18
3335-3344
2010
Clostridium perfringens, Vibrio cholerae serotype O1
Santos-Lopez, G.; Scior, T.; Borraz-Argueello, M.d.e.l..T.; Vallejo-Ruiz, V.; Herrera-Camacho, I.; Tapia-Ramirez, J.; Reyes-Leyva, J.
Structure-function analysis of two variants of mumps virus hemagglutinin-neuraminidase protein
Braz. J. Infect. Dis.
13
24-34
2009
Mumps orthorubulavirus, Mumps orthorubulavirus Urabe AM9
Mercader, A.G.; Pomilio, A.B.
QSAR study of flavonoids and biflavonoids as influenza H1N1 virus neuraminidase inhibitors
Eur. J. Med. Chem.
45
1724-1730
2010
influenza A virus
Bigi, A.; Morosi, L.; Pozzi, C.; Forcella, M.; Tettamanti, G.; Venerando, B.; Monti, E.; Fusi, P.
Human sialidase NEU4 long and short are extrinsic proteins bound to outer mitochondrial membrane and the endoplasmic reticulum, respectively
Glycobiology
20
148-157
2010
Homo sapiens
Cheng, J.; Huang, S.; Yu, H.; Li, Y.; Lau, K.; Chen, X.
Trans-sialidase activity of Photobacterium damsela alpha2,6-sialyltransferase and its application in the synthesis of sialosides
Glycobiology
20
260-268
2010
Photobacterium damselae
Mochalova, L.; Bright, R.; Xu, X.; Korchagina, E.; Chinarev, A.; Bovin, N.; Klimov, A.
Shift in oligosaccharide specificities of hemagglutinin and neuraminidase of influenza B viruses resistant to neuraminidase inhibitors
Glycoconj. J.
27
321-327
2010
influenza B virus (P27907)
Parker, D.; Soong, G.; Planet, P.; Brower, J.; Ratner, A.J.; Prince, A.
The NanA neuraminidase of Streptococcus pneumoniae is involved in biofilm formation
Infect. Immun.
77
3722-3730
2009
Streptococcus pneumoniae
Chiarezza, M.; Lyras, D.; Pidot, S.J.; Flores-Diaz, M.; Awad, M.M.; Kennedy, C.L.; Cordner, L.M.; Phumoonna, T.; Poon, R.; Hughes, M.L.; Emmins, J.J.; Alape-Giron, A.; Rood, J.I.
The NanI and NanJ sialidases of Clostridium perfringens are not essential for virulence
Infect. Immun.
77
4421-4428
2009
Clostridium perfringens, Clostridium perfringens type A
Sung, J.C.; Van Wynsberghe, A.W.; Amaro, R.E.; Li, W.W.; McCammon, J.A.
Role of secondary sialic acid binding sites in influenza N1 neuraminidase
J. Am. Chem. Soc.
132
2883-2885
2010
influenza A virus (P06820)
Kim, S.; Oh, D.B.; Kwon, O.; Kang, H.A.
Identification and functional characterization of the NanH extracellular sialidase from Corynebacterium diphtheriae
J. Biochem.
147
523-533
2010
Corynebacterium diphtheriae (C6JSW6), Corynebacterium diphtheriae, Corynebacterium diphtheriae KCTC3075 (C6JSW6)
Morley, T.J.; Willis, L.M.; Whitfield, C.; Wakarchuk, W.W.; Withers, S.G.
A new sialidase mechanism: bacteriophage K1F endo-sialidase is an inverting glycosidase
J. Biol. Chem.
284
17404-17410
2009
Escherichia phage K1F
Bonten, E.J.; Campos, Y.; Zaitsev, V.; Nourse, A.; Waddell, B.; Lewis, W.; Taylor, G.; dAzzo, A.
Heterodimerization of the sialidase NEU1 with the chaperone protective protein/cathepsin A prevents its premature oligomerization
J. Biol. Chem.
284
28430-28441
2009
Homo sapiens
Seyrantepe, V.; Iannello, A.; Liang, F.; Kanshin, E.; Jayanth, P.; Samarani, S.; Szewczuk, M.R.; Ahmad, A.; Pshezhetsky, A.V.
Regulation of phagocytosis in macrophages by neuraminidase 1
J. Biol. Chem.
285
206-215
2010
Mus musculus (O35657), Mus musculus
Baz, M.; Abed, Y.; Simon, P.; Hamelin, M.E.; Boivin, G.
Effect of the neuraminidase mutation H274Y conferring resistance to oseltamivir on the replicative capacity and virulence of old and recent human influenza A(H1N1) viruses
J. Infect. Dis.
201
740-745
2010
Influenza A virus (A/Brisbane/59/2007(H1N1))
Xu, G.; Ryan, C.; Kiefel, M.J.; Wilson, J.C.; Taylor, G.L.
Structural studies on the Pseudomonas aeruginosa sialidase-like enzyme PA2794 suggest substrate and mechanistic variations
J. Mol. Biol.
386
828-840
2009
Pseudomonas aeruginosa
Wang, J.; Wu, G.; Miyagi, T.; Lu, Z.H.; Ledeen, R.W.
Sialidase occurs in both membranes of the nuclear envelope and hydrolyzes endogenous GD1a
J. Neurochem.
111
547-554
2009
Homo sapiens (Q99519), Homo sapiens (Q9UQ49)
Hurt, A.C.; Holien, J.K.; Parker, M.; Kelso, A.; Barr, I.G.
Zanamivir-resistant influenza viruses with a novel neuraminidase mutation
J. Virol.
83
10366-10373
2009
influenza A virus (Q07599)
Gong, K.; Li, L.; Wang, J.F.; Cheng, F.; Wei, D.Q.; Chou, K.C.
Binding mechanism of H5N1 influenza virus neuraminidase with ligands and its implication for drug design
Med. Chem.
5
242-249
2009
unidentified influenza virus, unidentified influenza virus H5N1
Tanaka, M.; Sun, B.; Tezuka, K.; Fujisawa, J.; Tanaka, Y.; Hoshino, H.; Miwa, M.
Neuraminidase enhances the initial steps of human T-cell leukemia virus type 1 replication
Microbes Infect.
12
119-125
2010
Paenarthrobacter ureafaciens
Cao, H.; Li, Y.; Lau, K.; Muthana, S.; Yu, H.; Cheng, J.; Chokhawala, H.A.; Sugiarto, G.; Zhang, L.; Chen, X.
Sialidase substrate specificity studies using chemoenzymatically synthesized sialosides containing C5-modified sialic acids
Org. Biomol. Chem.
7
5137-5145
2009
Clostridium perfringens, Streptococcus pneumoniae, Pasteurella multocida, Salmonella enterica subsp. enterica serovar Typhimurium, Vibrio cholerae serotype O1
Cui, Y.; Jiao, Z.; Gong, J.; Yu, Q.; Zheng, X.; Quan, J.; Luo, M.; Yang, Z.
Development of new stereodiverse diaminocyclitols as inhibitors of influenza virus neuraminidase
Org. Lett.
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4-7
2010
influenza A virus
Hu, S.; Wang, T.; Liu, Y.; Meng, C.; Wang, X.; Wu, Y.; Liu, X.
Identification of a variable epitope on the Newcastle disease virus hemagglutinin-neuraminidase protein
Vet. Microbiol.
140
92-97
2010
Avian orthoavulavirus 1, Avian orthoavulavirus 1 (A2THD4), Avian orthoavulavirus 1 (A7L4X3), Avian orthoavulavirus 1 (A7UC53), Avian orthoavulavirus 1 (A7UC55), Avian orthoavulavirus 1 (A7UC57), Avian orthoavulavirus 1 (A7UC61), Avian orthoavulavirus 1 (A7UC62), Avian orthoavulavirus 1 (A7UC63), Avian orthoavulavirus 1 (A7UC64), Avian orthoavulavirus 1 (A7UC67), Avian orthoavulavirus 1 (A7UC69), Avian orthoavulavirus 1 (A7UC70), Avian orthoavulavirus 1 (Q83758), Avian orthoavulavirus 1 (Q914X2), Avian orthoavulavirus 1 (Q9W8Z8), Avian orthoavulavirus 1 JS-03/05 (A7UC55), Avian orthoavulavirus 1 JS-01/05 (A7L4X3), Avian orthoavulavirus 1 V4 (Q83758), Avian orthoavulavirus 1 Herts/33 (Q914X2), Avian orthoavulavirus 1 JS-07/05 (A7UC61), Avian orthoavulavirus 1 JS-02/05 (A7UC53), Avian orthoavulavirus 1 Mukteswar (A2THD4), Avian orthoavulavirus 1 JS-10/05 (A7UC70), Avian orthoavulavirus 1 GX-04/05 (A7UC67), Avian orthoavulavirus 1 ZJ-01/00 (Q914X2), Avian orthoavulavirus 1 ZhJ-3/97, Avian orthoavulavirus 1 JS-06/05 (A7UC69), Avian orthoavulavirus 1 JS-08/05 (A7UC62), Avian orthoavulavirus 1 La Sota (Q9W8Z8), Avian orthoavulavirus 1 JS-09/05 (A7UC63)
Bull, J.J.; Vimr, E.R.; Molineux, I.J.
A tale of tails: Sialidase is key to success in a model of phage therapy against K1-capsulated Escherichia coli
Virology
398
79-86
2010
no activity in Escherichia phage K1-ind(1), Siphoviridae
Jahangir, A.; Ruenphet, S.; Shoham, D.; Okamura, M.; Nakamaura, M.; Takehara, K.
Haemagglutinin and neuraminidase characterization of low pathogenic H5 and H7 avian influenza viruses isolated from Northern pintails (Anas acuta) in Japan, with special reference to genomic and biogeographical aspects
Virus Genes
40
94-105
2010
unidentified influenza virus, unidentified influenza virus H5, unidentified influenza virus H7
Kim, S.; Oh, D.B.; Kang, H.A.; Kwon, O.
Features and applications of bacterial sialidases
Appl. Microbiol. Biotechnol.
91
1-15
2011
Trypanosoma congolense (Q7YZT3)
Sandbhor, M.S.; Soya, N.; Albohy, A.; Zheng, R.B.; Cartmell, J.; Bundle, D.R.; Klassen, J.S.; Cairo, C.W.
Substrate recognition of the membrane-associated sialidase NEU3 requires a hydrophobic aglycone
Biochemistry
50
6753-6762
2011
Homo sapiens
Liu, Y.; Jing, F.; Xu, Y.; Xie, Y.; Shi, F.; Fang, H.; Li, M.; Xu, W.
Design, synthesis and biological activity of thiazolidine-4-carboxylic acid derivatives as novel influenza neuraminidase inhibitors
Bioorg. Med. Chem.
19
2342-2348
2011
influenza A virus
Albohy, A.; Li, M.D.; Zheng, R.B.; Zou, C.; Cairo, C.W.
Insight into substrate recognition and catalysis by the human neuraminidase 3 (NEU3) through molecular modeling and site-directed mutagenesis
Glycobiology
20
1127-1138
2010
Homo sapiens (Q9UQ49), Homo sapiens
Warwas, M.L.; Yeung, J.H.; Indurugalla, D.; Mooers, A.O.; Bennet, A.J.; Moore, M.M.
Cloning and characterization of a sialidase from the filamentous fungus, Aspergillus fumigatus
Glycoconj. J.
27
533-548
2010
Aspergillus fumigatus, Aspergillus fumigatus Af293
Estevez, C.; King, D.J.; Luo, M.; Yu, Q.
A single amino acid substitution in the haemagglutinin-neuraminidase protein of Newcastle disease virus results in increased fusion promotion and decreased neuraminidase activities without changes in virus pathotype
J. Gen. Virol.
92
544-551
2011
Avian orthoavulavirus 1, Avian orthoavulavirus 1 Anhinga/US(FL)/44083/93
Mohan, S.; McAtamney, S.; Haselhorst, T.; von Itzstein, M.; Pinto, B.M.
Carbocycles related to oseltamivir as influenza virus group-1-specific neuraminidase inhibitors. Binding to N1 enzymes in the context of virus-like particles
J. Med. Chem.
53
7377-7391
2010
influenza A virus
Raab, M.; Tvaroska, I.
The binding properties of the H5N1 influenza virus neuraminidase as inferred from molecular modeling
J. Mol. Model.
17
1445-1456
2011
influenza A virus
Tsurudome, M.; Ito, M.; Nishio, M.; Nakahashi, M.; Kawano, M.; Komada, H.; Nosaka, T.; Ito, Y.
Identification of domains on the fusion (F) protein trimer that influence the hemagglutinin-neuraminidase specificity of the of protein in mediating cell-cell fusion
J. Virol.
85
3153-3161
2011
Mammalian orthorubulavirus 5
Yang, Y.; Chang, S.; Gong, X.; Wu, J.; Liu, B.
Expression, purification and characterization of low-glycosylation influenza neuraminidase in alpha-1,6-mannosyltransferase defective Pichia pastoris
Mol. Biol. Rep.
39
857-864
2011
influenza A virus (Q7TG96), influenza A virus newCaledonia/20/99(H1N1) (Q7TG96)
Li, Y.; Cao, H.; Yu, H.; Chen, Y.; Lau, K.; Qu, J.; Thon, V.; Sugiarto, G.; Chen, X.
Identifying selective inhibitors against the human cytosolic sialidase NEU2 by substrate specificity studies
Mol. Biosyst.
7
1060-1072
2011
Homo sapiens
Harrison, J.A.; Kartha, K.P.; Fournier, E.J.; Lowary, T.L.; Malet, C.; Nilsson, U.J.; Hindsgaul, O.; Schenkman, S.; Naismith, J.H.; Field, R.A.
Probing the acceptor substrate binding site of Trypanosoma cruzi trans-sialidase with systematically modified substrates and glycoside libraries
Org. Biomol. Chem.
9
1653-1660
2011
Trypanosoma cruzi
Wu, J.; Zhang, F.; Wang, M.; Xu, C.; Song, J.; Zhou, J.; Lin, X.; Zhang, Y.; Wu, X.; Tan, W.; Lu, J.; Zhao, H.; Gao, J.; Zhao, P.; Lu, J.; Wang, Y.
Characterization of neuraminidases from the highly pathogenic avian H5N1 and 2009 pandemic H1N1 influenza A viruses
PLoS ONE
5
e15825
2010
influenza A virus, influenza A virus A/Hong Kong/156/97/H5N1, influenza A virus A/California/05/2009/H1N1
Li, Y.; Cao, H.; Dao, N.; Luo, Z.; Yu, H.; Chen, Y.; Xing, Z.; Baumgarth, N.; Cardona, C.; Chen, X.
High-throughput neuraminidase substrate specificity study of human and avian influenza A viruses
Virology
415
12-19
2011
influenza A virus
Engibarov, S.; Eneva, R.; Abrashev, I.
Neuraminidase (sialidase) from Aeromonas sp. strain 40/02 - isolation and partial purification
Ann. Microbiol.
65
15151523
2015
Aeromonas sp., Aeromonas sp. 40/02
Sakarya, S.; Gunay, N.
Saccharomyces boulardii expresses neuraminidase activity selective for alpha2,3-linked sialic acid that decreases Helicobacter pylori adhesion to host cells
APMIS
122
941-950
2014
Saccharomyces boulardii (nom. inval.)
Li, J.; McClane, B.A.
The sialidases of Clostridium perfringens type D strain CN3718 differ in their properties and sensitivities to inhibitors
Appl. Environ. Microbiol.
80
1701-1709
2014
Clostridium perfringens, Clostridium perfringens CN3718
Yeung, J.H.; Telford, J.C.; Shidmoossavee, F.S.; Bennet, A.J.; Taylor, G.L.; Moore, M.M.
Kinetic and structural evaluation of selected active site mutants of the Aspergillus fumigatus KDNase (sialidase)
Biochemistry
52
9177-9186
2013
Aspergillus fumigatus (Q4WQS0), Aspergillus fumigatus, Aspergillus fumigatus Af293 (Q4WQS0)
Cheng, L.L.; Shidmoossavee, F.S.; Bennet, A.J.
Neuraminidase substrate promiscuity permits a mutant Micromonospora viridifaciens enzyme to synthesize artificial carbohydrates
Biochemistry
53
3982-3989
2014
Micromonospora viridifaciens (Q02834), Micromonospora viridifaciens
Park, K.H.; Kim, M.G.; Ahn, H.J.; Lee, D.H.; Kim, J.H.; Kim, Y.W.; Woo, E.J.
Structural and biochemical characterization of the broad substrate specificity of Bacteroides thetaiotaomicron commensal sialidase
Biochim. Biophys. Acta
1834
1510-1519
2013
Bacteroides thetaiotaomicron (Q8AAK9), Bacteroides thetaiotaomicron, Bacteroides thetaiotaomicron VPI-5482 (Q8AAK9)
Kim, J.H.; Ryu, Y.B.; Lee, W.S.; Kim, Y.H.
Neuraminidase inhibitory activities of quaternary isoquinoline alkaloids from Corydalis turtschaninovii rhizome
Bioorg. Med. Chem.
22
6047-6052
2014
Clostridium perfringens
Wu, Y.; Bi, Y.; Vavricka, C.J.; Sun, X.; Zhang, Y.; Gao, F.; Zhao, M.; Xiao, H.; Qin, C.; He, J.; Liu, W.; Yan, J.; Qi, J.; Gao, G.F.
Characterization of two distinct neuraminidases from avian-origin human-infecting H7N9 influenza viruses
Cell Res.
23
1347-1355
2013
H7N9 subtype (R4JGE3), H7N9 subtype (R4RZI6), H7N9 subtype, H7N9 subtype A/Shanghai/1/2013 (R4RZI6), H7N9 subtype A/Anhui/1/2013 (R4JGE3)
Naumov, P.; Yasuda, N.; Rabeh, W.M.; Bernstein, J.
The elusive crystal structure of the neuraminidase inhibitor Tamiflu (oseltamivir phosphate): molecular details of action
Chem. Commun. (Camb. )
49
1948-1950
2013
influenza A virus (Q6DPL2)
Zeuner, B.; Luo, J.; Nyffenegger, C.; Aumala, V.; Mikkelsen, J.D.; Meyer, A.S.
Optimizing the biocatalytic productivity of an engineered sialidase from Trypanosoma rangeli for 3-sialyllactose production
Enzyme Microb. Technol.
55
85-93
2014
Trypanosoma rangeli
Shiozaki, K.; Ryuzono, S.; Matsushita, N.; Ikeda, A.; Takeshita, K.; Chigwechokha, P.K.; Komatsu, M.; Miyagi, T.
Molecular cloning and biochemical characterization of medaka (Oryzias latipes) lysosomal neu4 sialidase
Fish Physiol. Biochem.
40
1461-1472
2014
Oryzias latipes (L0N7M7), Oryzias latipes
Chigwechokha, P.K.; Komatsu, M.; Itakura, T.; Shiozaki, K.
Nile Tilapia Neu3 sialidases: molecular cloning, functional characterization and expression in Oreochromis niloticus
Gene
552
155-164
2014
Oreochromis niloticus (A0A024FS29), Oreochromis niloticus (A0A024FSF5), Oreochromis niloticus (I3JCG9), Oreochromis niloticus
Bigi, A.; Tringali, C.; Forcella, M.; Mozzi, A.; Venerando, B.; Monti, E.; Fusi, P.
A proline-rich loop mediates specific functions of human sialidase NEU4 in SK-N-BE neuronal differentiation
Glycobiology
23
1499-1509
2013
Homo sapiens
Albohy, A.; Richards, M.R.; Cairo, C.W.
Mapping substrate interactions of the human membrane-associated neuraminidase, NEU3, using STD NMR
Glycobiology
25
284-293
2015
Homo sapiens (Q9UQ49), Homo sapiens
Cross, A.S.; Hyun, S.W.; Miranda-Ribera, A.; Feng, C.; Liu, A.; Nguyen, C.; Zhang, L.; Luzina, I.G.; Atamas, S.P.; Twaddell, W.S.; Guang, W.; Lillehoj, E.P.; Puche, A.C.; Huang, W.; Wang, L.X.; Passaniti, A.; Goldblum, S.E.
NEU1 and NEU3 sialidase activity expressed in human lung microvascular endothelia: NEU1 restrains endothelial cell migration, whereas NEU3 does not
J. Biol. Chem.
287
15966-15980
2012
Homo sapiens (Q99519), Homo sapiens (Q9UQ49), Homo sapiens
von Grafenstein, S.; Wallnoefer, H.G.; Kirchmair, J.; Fuchs, J.E.; Huber, R.G.; Schmidtke, M.; Sauerbrei, A.; Rollinger, J.M.; Liedl, K.R.
Interface dynamics explain assembly dependency of influenza neuraminidase catalytic activity
J. Biomol. Struct. Dyn.
33
104-120
2015
influenza A virus
Fujisaki, S.; Imai, M.; Takashita, E.; Taniwaki, T.; Xu, H.; Kishida, N.; Yokoyama, M.; Sato, H.; Tashiro, M.; Odagiri, T.
Mutations at the monomer-monomer interface away from the active site of influenza B virus neuraminidase reduces susceptibility to neuraminidase inhibitor drugs
J. Infect. Chemother.
19
891-895
2013
influenza B virus, influenza B virus B/Kochi/41/2011, influenza B virus B/Kochi/59/2011, influenza B virus B/Kochi/60/2011
Bueren-Calabuig, J.A.; Pierdominici-Sottile, G.; Roitberg, A.E.
Unraveling the differences of the hydrolytic activity of Trypanosoma cruzi trans-sialidase and Trypanosoma rangeli sialidase: a quantum mechanics-molecular mechanics modeling study
J. Phys. Chem. B
118
5807-5816
2014
Trypanosoma rangeli
Halbherr, S.J.; Ludersdorfer, T.H.; Ricklin, M.; Locher, S.; Berger Rentsch, M.; Summerfield, A.; Zimmer, G.
Biological and protective properties of immune sera directed to influenza virus neuraminidase
J. Virol.
89
1550-1563
2015
influenza A virus, influenza A virus H7N7
Baek, Y.H.; Song, M.S.; Lee, E.Y.; Kim, Y.I.; Kim, E.H.; Park, S.J.; Park, K.J.; Kwon, H.I.; Pascua, P.N.; Lim, G.J.; Kim, S.; Yoon, S.W.; Kim, M.H.; Webby, R.J.; Choi, Y.K.
Profiling and characterization of potentially multidrug-resistant influenza neuraminidase 1 (N1) strains against neuraminidase inhibitors
J. Virol.
89
287-299
2015
influenza A virus (A9YLL2), influenza A virus (C3W5S3)
Kurniyati, K.; Zhang, W.; Zhang, K.; Li, C.
A surface-exposed neuraminidase affects complement resistance and virulence of the oral spirochaete Treponema denticola
Mol. Microbiol.
89
842-856
2013
Treponema denticola (Q73QH2), Treponema denticola, Treponema denticola ATCC 35405 (Q73QH2)
Khedri, Z.; Li, Y.; Cao, H.; Qu, J.; Yu, H.; Muthana, M.M.; Chen, X.
Synthesis of selective inhibitors against V. cholerae sialidase and human cytosolic sialidase NEU2
Org. Biomol. Chem.
10
6112-6120
2012
Streptococcus pneumoniae, Vibrio cholerae (P0C6E9), Vibrio cholerae, Clostridium perfringens (P10481), Salmonella enterica subsp. enterica serovar Typhimurium (P29768), Homo sapiens (Q9Y3R4), Homo sapiens
Nishikawa, T.; Shimizu, K.; Tanaka, T.; Kuroda, K.; Takayama, T.; Yamamoto, T.; Hanada, N.; Hamada, Y.
Bacterial neuraminidase rescues influenza virus replication from inhibition by a neuraminidase inhibitor
PLoS ONE
7
e45371
2012
influenza A virus, Paenarthrobacter ureafaciens, Streptococcus pneumoniae, Streptococcus pneumoniae IID553, Vibrio cholerae serotype O1
Bonardi, D.; Ravasio, V.; Borsani, G.; dAzzo, A.; Bresciani, R.; Monti, E.; Giacopuzzi, E.
In silico identification of new putative pathogenic variants in the NEU1 sialidase gene affecting enzyme function and subcellular localization
PLoS ONE
9
e104229
2014
Homo sapiens (Q99519), Homo sapiens
Yang, X.; Steukers, L.; Forier, K.; Xiong, R.; Braeckmans, K.; Van Reeth, K.; Nauwynck, H.
A beneficiary role for neuraminidase in influenza virus penetration through the respiratory mucus
PLoS ONE
9
e110026
2014
Paenarthrobacter ureafaciens
Bonardi, D.; Papini, N.; Pasini, M.; Dileo, L.; Orizio, F.; Monti, E.; Caimi, L.; Venerando, B.; Bresciani, R.
Sialidase NEU3 dynamically associates to different membrane domains specifically modifying their ganglioside pattern and triggering Akt phosphorylation
PLoS ONE
9
e99405
2014
Homo sapiens (Q9UQ49)
Mozzi, A.; Mazzacuva, P.; Zampella, G.; Forcella, M.E.; Fusi, P.A.; Monti, E.
Molecular insight into substrate recognition by human cytosolic sialidase NEU2
Proteins
80
1123-1132
2012
Homo sapiens (Q9Y3R4), Homo sapiens
Gerlach, T.; Kuehling, L.; Uhlendorff, J.; Laukemper, V.; Matrosovich, T.; Czudai-Matwich, V.; Schwalm, F.; Klenk, H.D.; Matrosovich, M.
Characterization of the neuraminidase of the H1N1/09 pandemic influenza virus
Vaccine
30
7348-7352
2012
unidentified influenza virus, unidentified influenza virus H1N1/09
Sultana, I.; Yang, K.; Getie-Kebtie, M.; Couzens, L.; Markoff, L.; Alterman, M.; Eichelberger, M.C.
Stability of neuraminidase in inactivated influenza vaccines
Vaccine
32
2225-2230
2014
influenza A virus, influenza A virus H3N2, influenza B virus
Onsirisakul, N.; Nakakita, S.; Boonarkart, C.; Kongchanagul, A.; Suptawiwat, O.; Puthavathana, P.; Chaichuen, K.; Kittiniyom, K.; Suzuki, Y.; Auewarakul, P.
Substrate specificity of avian influenza H5N1 neuraminidase
World J. Virol.
3
30-36
2014
influenza A virus
Hunter, C.D.; Khanna, N.; Richards, M.R.; Rezaei Darestani, R.; Zou, C.; Klassen, J.S.; Cairo, C.W.
Human neuraminidase isoenzymes show variable activities for 9-O-acetyl-sialoside substrates
ACS Chem. Biol.
13
922-932
2018
Homo sapiens
Gattu, S.; Crihfield, C.L.; Holland, L.A.
Microscale measurements of Michaelis-Menten constants of neuraminidase with nanogel capillary electrophoresis for the determination of the sialic acid linkage
Anal. Chem.
89
929-936
2017
Clostridium perfringens
Tu, V.; Abed, Y.; Fage, C.; Baz, M.; Boivin, G.
Impact of R152K and R368K neuraminidase catalytic substitutions on in vitro properties and virulence of recombinant A(H1N1)pdm09 viruses
Antiviral Res.
154
110-115
2018
unidentified influenza virus, unidentified influenza virus A/Quebec/144147/09
Guo, L.; Chen, X.; Xu, L.; Xiao, M.; Lu, L.
Enzymatic synthesis of 6-sialyllactose, a dominant sialylated human milk oligosaccharide, by a novel exo-alpha-sialidase from Bacteroides fragilis NCTC9343
Appl. Environ. Microbiol.
84
e00071-18
2018
Bacteroides fragilis (Q5L868), Bacteroides fragilis, Bacteroides fragilis NCTC 9343 (Q5L868), Bacteroides fragilis NCTC 9343
Lee, Y.; Youn, H.S.; Lee, J.G.; An, J.Y.; Park, K.R.; Kang, J.Y.; Ryu, Y.B.; Jin, M.S.; Park, K.H.; Eom, S.H.
Crystal structure of the catalytic domain of Clostridium perfringens neuraminidase in complex with a non-carbohydrate-based inhibitor, 2-(cyclohexylamino)ethanesulfonic acid
Biochem. Biophys. Res. Commun.
486
470-475
2017
Clostridium perfringens
Paolini, L.; Orizio, F.; Busatto, S.; Radeghieri, A.; Bresciani, R.; Bergese, P.; Monti, E.
Exosomes secreted by hela cells shuttle on their surface the plasma membrane-associated sialidase NEU3
Biochemistry
56
6401-6408
2017
Homo sapiens
McCombs, J.E.; Kohler, J.J.
Pneumococcal neuraminidase substrates identified through comparative proteomics enabled by chemoselective labeling
Bioconjug. Chem.
27
1013-1022
2016
Streptococcus pneumoniae
Ashida, H.; Tanigawa, K.; Kiyohara, M.; Katoh, T.; Katayama, T.; Yamamoto, K.
Bifunctional properties and characterization of a novel sialidase with esterase activity from Bifidobacterium bifidum
Biosci. Biotechnol. Biochem.
82
2030-2039
2018
Bifidobacterium bifidum, Bifidobacterium bifidum JCM1254
Hata, K.; Tochigi, T.; Sato, I.; Kawamura, S.; Shiozaki, K.; Wada, T.; Takahashi, K.; Moriya, S.; Yamaguchi, K.; Hosono, M.; Miyagi, T.
Increased sialidase activity in serum of cancer patients Identification of sialidase and inhibitor activities in human serum
Cancer Sci.
106
383-389
2015
Homo sapiens
Huang, K.; Wang, M.M.; Kulinich, A.; Yao, H.L.; Ma, H.Y.; Martinez, J.E.; Duan, X.C.; Chen, H.; Cai, Z.P.; Flitsch, S.L.; Liu, L.; Voglmeir, J.
Biochemical characterisation of the neuraminidase pool of the human gut symbiont Akkermansia muciniphila
Carbohydr. Res.
415
60-65
2015
Akkermansia muciniphila, Akkermansia muciniphila DSM 22959
Minami, A.; Ishii, A.; Shimba, S.; Kano, T.; Fujioka, E.; Sai, S.; Oshio, N.; Ishibashi, S.; Takahashi, T.; Kurebayashi, Y.; Kanazawa, H.; Yuki, N.; Otsubo, T.; Ikeda, K.; Suzuki, T.
Down-regulation of glutamate release from hippocampal neurons by sialidase
J. Biochem.
163
273-280
2018
Rattus norvegicus
Du, W.; Dai, M.; Li, Z.; Boons, G.J.; Peeters, B.; van Kuppeveld, F.J.M.; de Vries, E.; de Haan, C.A.M.
Substrate binding by the second sialic acid-binding site of influenza A virus N1 neuraminidase contributes to enzymatic activity
J. Virol.
92
e01243-18
2018
influenza A virus H1N1 (M1VAT9), influenza A virus H5N1 (Q6DPL4)
Lloren, K.K.S.; Kwon, J.J.; Choi, W.S.; Jeong, J.H.; Ahn, S.J.; Choi, Y.K.; Baek, Y.H.; Song, M.S.
In vitro and in vivo characterization of novel neuraminidase substitutions in influenza A(H1N1)pdm09 virus identified using laninamivir-mediated in vitro selection
J. Virol.
93
e01825-18
2019
influenza A virus H1N1, influenza A virus H1N1 pdm09
Weininger, A.; Weininger, S.
Using common spatial distributions of atoms to relate functionally divergent influenza virus N10 and N11 protein structures to functionally characterized neuraminidase structures, toxin cell entry domains, and non-influenza virus cell entry domains
PLoS ONE
10
e0117499
2015
no activity in influenza A virus H17N10, no activity in influenza A virus H18N11
Prevato, M.; Ferlenghi, I.; Bonci, A.; Uematsu, Y.; Anselmi, G.; Giusti, F.; Bertholet, S.; Legay, F.; Telford, J.L.; Settembre, E.C.; Maione, D.; Cozzi, R.
Expression and characterization of recombinant, tetrameric and enzymatically active influenza neuraminidase for the setup of an enzyme-linked lectin-based assay
PLoS ONE
10
e0135474
2015
influenza A virus H1N1 (C7FH46), influenza A virus H5N1 (A5Z227)
Cuevas-Romero, J.S.; Rivera-Benitez, J.F.; Hernandez-Baumgarten, E.; Hernandez-Jauregui, P.; Vega, M.; Blomstroem, A.L.; Berg, M.; Baule, C.
Cloning, expression and characterization of potential immunogenic recombinant hemagglutinin-neuraminidase protein of Porcine rubulavirus
Protein Expr. Purif.
128
1-7
2016
Porcine orthorubulavirus
Pokorna, J.; Pachl, P.; Karlukova, E.; Hejdanek, J.; Rezacova, P.; Machara, A.; Hudlicky, J.; Konvalinka, J.; Kozisek, M.
Kinetic, Thermodynamic, and structural analysis of drug resistance mutations in neuraminidase from the 2009 pandemic Influenza virus
Viruses
10
E339
2018
influenza A virus H1N1 (C3W6G3)
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