Information on EC 3.2.1.124 - 3-deoxy-2-octulosonidase

Word Map on EC 3.2.1.124
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The enzyme appears in viruses and cellular organisms

EC NUMBER
COMMENTARY hide
3.2.1.124
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RECOMMENDED NAME
GeneOntology No.
3-deoxy-2-octulosonidase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
endohydrolysis of the beta-ketopyranosidic linkages of 3-deoxy-D-manno-2-octulosonate in capsular polysaccharides
show the reaction diagram
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-
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-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
hydrolysis of O-glycosyl bond
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-
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SYSTEMATIC NAME
IUBMB Comments
capsular-polysaccharide 3-deoxy-D-manno-2-octulosonohydrolase
The enzyme from a bacteriophage catalyses the depolymerization of capsular polysaccharides containing 3-deoxy-2-octulosonide in the cell wall of Escherichia coli.
CAS REGISTRY NUMBER
COMMENTARY hide
103171-48-8
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
Coliphage PHI20
growing on Escherichia coli K13, K20 or K23
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Manually annotated by BRENDA team
Coliphage PHI95
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Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
malfunction
physiological function
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
1-dephosphorylated Kdo2-lipid A + H2O
?
show the reaction diagram
3-deoxy-D-manno-2-octulosonic acid glycoside + H2O
tetrasaccharide of two repeating units
show the reaction diagram
Kdo2-lipid A + H2O
?
show the reaction diagram
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
3-deoxy-D-manno-2-octulosonic acid glycoside + H2O
tetrasaccharide of two repeating units
show the reaction diagram
Coliphage PHI20
-
catalyzes depolymerization of 3-deoxy-2-octulosonide containing capsular polysaccharides from E. coli K13, K20 and K23
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-
?
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
6.5
Coliphage PHI95
-
assay at
TEMPERATURE OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
30
Coliphage PHI95
-
assay at
37
Coliphage PHI20
-
assay at
Cloned/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
expressed in Escherichia coli DH5alpha cells
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expressed in Escherichia coli HMS174 cells
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