Reference on EC 3.2.1.108 - lactase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Mbuyi-Kalala, A.; Schnek, A.G.; Leonis, J.
Separation and characterization of four enzyme forms of beta-galactosidase from Saccharomyces lactis
Eur. J. Biochem.
178
437-443
1988
Kluyveromyces lactis, Homo sapiens, Sediminibacterium lactis
Lau, H.K.F.
Physicochemical characterization of human intestinal lactase
Biochem. J.
241
567-572
1987
Homo sapiens
Day, A.J.; Canada, F.J.; Diaz, J.C.; Kroon, P.A.; Mclauchlan, R.; Faulds, C.B.; Plumb, G.W.; Morgan, M.R.A.; Williamson, G.
Dietary flavonoids and isoflavone glycosides are hydrolysed by the lactase site of lactase phlorizin hydrolase
FEBS Lett.
468
166-170
2000
Ovis aries
Jacob, R.; Weiner, J.R.; Stadge, S.; Naim, H.Y.
Additional N-glycosylation and its impact on the folding of intestinal lactase-phlorizin hydrolase
J. Biol. Chem.
275
10630-10637
2000
Homo sapiens
Estrada, G.; Krasinski, S.D.; Montgomery, R.K.; Grand, R.J.; Garcia-Valero, J.; Lopez-Tejero, M.D.
Quantitative analysis of lactase-phlorizin hydrolase expression in the absorptive enterocytes of newborn rat small intestine
J. Cell. Physiol.
167
341-348
1996
Rattus
Naim, H.Y.
The pro-region of human intestinale lactase-phlorizin hydrolase is enzymatically inactive towards lactose
Biol. Chem. Hoppe-Seyler
376
255-258
1995
Homo sapiens
Wacker, H.; Keller, P.; Falchetto, R.; Legler, G.; Semenza, G.
Location of the two catalytic sites in intestinal lactase-phlorizin hydrolase
J. Biol. Chem.
267
18744-18752
1992
Oryctolagus cuniculus
Skovbjerg, H.; Sjöström, H.; Noren, O.
Purification and characterization of amphiphilic lactase/phlorizin hydrolase from human small intestine
Eur. J. Biochem.
114
653-661
1981
Homo sapiens
Skovbjerg, H.; Noren, O.; Sjöström, H.; Danielsen, E.M.; Enevoldsen, B.S.
Further characterization of intestinal lactase/phlorizin hydrolase
Biochim. Biophys. Acta
707
89-97
1982
BRENDA: Homo sapiens, Sus scrofa
Textmining: Suidae
Cousineau, J.; Green, J.R.
Isolation and characterization of the proximal and distal forms of lactase-phlorizin hydrolase from the small intestine of the suckling rat
Biochim. Biophys. Acta
615
147-157
1980
Rattus
Ramaswamy, S.; Radhakrishnan, A.N.
Lactase-phlorizin hydrolase complex from monkey small intestine. Purification, properties and evidence for two catalytic sites
Biochim. Biophys. Acta
403
446-455
1975
Platyrrhini
Kraml, J.; Kolinska, J.; Ellederova, D.; Hirsova, D.
beta-Glucosidase (phlorizin hydrolase) activity of the lactase fraction isolated from the small intestinal mucosa of infant rats, and the relationship between beta-glucosidases and beta-galactosidases
Biochim. Biophys. Acta
258
520-530
1972
Homo sapiens, Rattus
Schlegel-Haueter, S.; Hore, P.; Kerry, K.R.; Semenza, G.
The preparation of lactase and glucoamylase of rat small intestine
Biochim. Biophys. Acta
258
506-519
1972
BRENDA: Homo sapiens, Rattus norvegicus
Textmining: Rattus
Bueller, H.A.; Kothe, M.J.C.; Goldman, D.A.; Grubman, S.A.; Sasak, W.V.; Matsudaira, P.T.; Montgomery, R.K.; Grand, R.J.
Coordinate expression of lactate-phlorizin hydrolase mRNA and enzyme levels in rat intestine during development
J. Biol. Chem.
265
6978-6953
1990
BRENDA: Rattus norvegicus
Textmining: Rattus
Day, A.J.; Gee, J.M.; DuPont, M.S.; Johnson, I.T.; Williamson, G.
Absorption of quercetin-3-glucoside and quercetin-4'-glucoside in the rat small intestine: the role of lactase phlorizin hydrolase and the sodium-dependent glucose transporter
Biochem. Pharmacol.
65
1199-1206
2003
BRENDA: Rattus norvegicus
Textmining: Rattus
Arribas, J.C.; Herrero, A.G.; Martin-Lomas, M.; Canada, F.J.; He, S.; Withers, S.G.
Differential mechanism-based labeling and unequivocal activity assignment of the two active sites of intestinal lactase/phlorizin hydrolase
Eur. J. Biochem.
267
6996-7005
2000
Mammalia
Jacob, R.; Peters, K.; Naim, H.Y.
Prosequence of human lactase-phlorizin hydrolase modulates the folding of mature enzyme
J. Biol. Chem.
277
8217-8225
2002
Homo sapiens
Burrin, D.G.; Stoll, B.; Fan, M.Z.; Dudley, M.A.; Donovan, S.M.; Reeds, P.J.
Oral IGF-I alters the posttranslational processing but not the activity of lactase-phlorizin hydrolase in formula-fed neonatal pigs
J. Nutr.
131
2235-2241
2001
BRENDA: Sus scrofa
Textmining: Suidae
Wilkinson, A.P.; Gee, J.M.; Dupont, M.S.; Needs, P.W.; Mellon, F.A.; Williamson, G.; Johnson, I.T.
Hydrolysis by lactase phlorizin hydrolase is the first step in the uptake of daidzein glucosides by rat small intestine in vitro
Xenobiotica
33
255-264
2003
Rattus norvegicus
West, A.R.; Oates, P.S.
Decreased sucrase and lactase activity in iron deficiency is accompanied by reduced gene expression and upregulation of the transcriptional repressor PDX-1
Am. J. Physiol. Gastronintest. Liver Physiol.
289
G1108-G1114
2005
BRENDA: Rattus norvegicus
Textmining: Rattus
Hermida, C.; Corrales, G.; Martinez-Costa, O.H.; Fernandez-Mayoralas, A.; Aragon, J.J.
Noninvasive evaluation of intestinal lactase with 4-galactosylxylose: comparison with 3- and 2-galactosylxylose and optimization of the method in rats
Clin. Chem.
52
270-277
2006
BRENDA: Rattus norvegicus
Textmining: Rattus
Mohamed, S.A.; Fahmy, A.S.; Mohamed, T.M.
Carbohydrases in camel (Camelus dromedarius) pancreas. Purification and characterization of glucoamylase
Comp. Biochem. Physiol. B
140
73-80
2005
Camelus bactrianus, Bos taurus, Ovis aries
Lewinsky, R.H.; Jensen, T.G.; M?ller, J.; Stensballe, A.; Olsen, J.; Troelsen, J.T.
T-13910 DNA variant associated with lactase persistence interacts with Oct-1 and stimulates lactase promoter activity in vitro
Hum. Mol. Genet.
14
3945-3953
2005
Homo sapiens
Kuranuki, S.; Mochizuki, K.; Goda, T.
Dietary sucrose enhances intestinal lactase gene expression in euthyroid rats
J. Nutr. Sci. Vitaminol.
52
347-351
2006
BRENDA: Rattus norvegicus
Textmining: Rattus, Metazoa
Beau, I.; Cotte-Laffitte, J.; Geniteau-Legendre, M.; Estes, M.K.; Servin, A.L.
An NSP4-dependant mechanism by which rotavirus impairs lactase enzymatic activity in brush border of human enterocyte-like Caco-2 cells
Cell. Microbiol.
9
2254-2266
2007
BRENDA: Homo sapiens
Textmining: Rotavirus, Macaca mulatta
Fernandes, V.L.; Bhasin, D.K.; Rana, S.V.
Study of enzyme activities in the descending part of the duodenum in patients of duodenal ulcer
Indian J. Clin. Biochem.
21(1)
169-172
2006
Homo sapiens
Kuokkanen, M.; Kokkonen, J.; Enattah, N.S.; Ylisaukko-Oja, T.; Komu, H.; Varilo, T.; Peltonen, L.; Savilahti, E.; Jarvela, I.
Mutations in the translated region of the lactase gene (LCT) underlie congenital lactase deficiency
Am. J. Hum. Genet.
78
339-344
2006
Homo sapiens
He, W.; Ji, Z.Y.; Huang, C.Y.
Molecular cloning of a novel cDNA from Mus muscular BALB/c mice encoding glycosyl hydrolase family 1: a homolog of human lactase-phlorizin hydrolase
Biomed. Environ. Sci.
19
340-345
2006
BRENDA: Mus musculus, Mus musculus BALB/c
Textmining: Homo sapiens
Hermida, C.; Corrales, G.; Canada, F.J.; Aragon, J.J.; Fernandez-Mayoralas, A.
Optimizing the enzymatic synthesis of beta-D-galactopyranosyl-D-xyloses for their use in the evaluation of lactase activity in vivo
Bioorg. Med. Chem.
15
4836-4840
2007
BRENDA: Rattus norvegicus
Textmining: Rattus
Bernardes-Silva Carlos Felip, B.C.; Pereira Alexandre , P.A.; de Fatima Alves da Mota Glori, d.F.; Krieger Jose Eduard, K.J.; Laudanna Antonio Atili, L.A.
Lactase persistence/non-persistence variants, C/T_13910 and G/A_22018, as a diagnostic tool for lactose intolerance in IBS patients
Clin. Chim. Acta
386
7-11
2007
Homo sapiens
Tamura, A.; Shiomi, T.; Hachiya, S.; Shigematsu, N.; Hara, H.
Low activities of intestinal lactase suppress the early phase absorption of soy isoflavones in Japanese adults
Clin. Nutr.
27
248-253
2008
Homo sapiens
Imtiaz , I.F.; Savilahti , S.E.; Sarnesto , S.A.; Trabzuni , T.D.; Al-Kahtani , A.K.; Kagevi , K.I.; Rashed M. , R.M.; Meyer B. , M.B.; Jarvela , J.I.
The T/G 13915 variant upstream of the lactase gene (LCT) is the founder allele of lactase persistence in an urban Saudi population
J. Med. Genet.
44
e89-e89
2007
BRENDA: Homo sapiens
Textmining: Colotis, Arabia, Bos taurus
Chaudhry, K.K.; Mahmood, S.; Mahmood, A.
Hormone induced expression of brush border lactase in suckling rat intestine
Mol. Cell. Biochem.
312
11-16
2008
BRENDA: Rattus norvegicus
Textmining: Rattus, Rodentia, Metazoa, Homo sapiens
Piepoli, A.; Schirru, E.; Mastrorilli, A.; Gentile, A.; Cotugno, R.; Quitadamo, M.; Merla, A.; Congia, M.; Usai Satta, P.; Perri, F.
Genotyping of the lactase-phlorizin hydrolase c/t-13910 polymorphism by means of a new rapid denaturing high-performance liquid chromatography-based assay in healthy subjects and colorectal cancer patients
J. Biomol. Screen.
12
733-739
2007
Homo sapiens, Areas
O'Connell, S.; Walsh, G.
Application relevant studies of fungal beta-galactosidases with potential application in the alleviation of lactose intolerance
Appl. Biochem. Biotechnol.
149
129-138
2008
Aspergillus carbonarius
Tovar-Castro, L.; Garcia-Garibay, M.; Saucedo-Castaneda, G.
Lactase production by solid-state cultivation of Kluyveromyces marxianus CDBBL 278 on an inert support: effect of inoculum, buffer, and nitrogen source
Appl. Biochem. Biotechnol.
151
610-617
2008
Kluyveromyces marxianus CDBBL 278, Kluyveromyces marxianus
Torniainen, S.; Freddara, R.; Routi, T.; Gijsbers, C.; Catassi, C.; Hoeglund, P.; Savilahti, E.; Jaervelae, I.
Four novel mutations in the lactase gene (LCT) underlying congenital lactase deficiency (CLD)
BMC Gastroenterol.
9
8
2009
Homo sapiens (P09848), Homo sapiens
Karas-Kuzelicki, N.; Pfeifer, V.; Lukac-Bajalo, J.
Synergistic effect of high lactase activity genotype and galactose-1-phosphate uridyl transferase (GALT) mutations on idiopathic presenile cataract formation
Clin. Biochem.
41
869-874
2008
Homo sapiens
Behrendt, M.; Keiser, M.; Hoch, M.; Naim, H.Y.
Impaired trafficking and subcellular localization of a mutant lactase associated with congenital lactase deficiency
Gastroenterology
136
2295-2303
2009
Homo sapiens
Fabre, J.W.; Salehi, S.; Eckley, L.; Sawyer, G.J.; Zhang, X.; Dong, X.; Freund, J.N.
Intestinal lactase as an autologous beta-galactosidase reporter gene for in vivo gene expression studies
Hum. Gene Ther.
20
21-30
2008
BRENDA: Escherichia coli, Rattus norvegicus
Textmining: Homo sapiens, Metazoa, Mus sp., Rattus
Willing, B.P.; Van Kessel, A.G.
Intestinal microbiota differentially affect brush border enzyme activity and gene expression in the neonatal gnotobiotic pig
J. Anim. Physiol. Anim. Nutr. (Berl.)
93
586-595
2008
Sus scrofa (Q29587)
Tanaka, T.; Suzuki, A.; Kuranuki, S.; Mochizuki, K.; Suruga, K.; Takase, S.; Goda, T.
Higher expression of jejunal LPH gene in rats fed the high-carbohydrate/low-fat diet compared with those fed the low-carbohydrate/high-fat diet is associated with in vitro binding of Cdx-2 in nuclear proteins to its promoter regions
Life Sci.
83
122-127
2008
Rattus norvegicus
Chaudhry, K.K.; Mahmood, S.; Mahmood, A.
Hormone induced changes in lactase glycosylation in developing rat intestine
Mol. Cell. Biochem.
318
183-190
2008
BRENDA: Rattus norvegicus
Textmining: Rattus
Khabarova, Y.A.; Torniainen, S.T.; Nurmi, H.A.; Jaervelae, I.E.; Isokoski, M.K.; Mattila, K.J.
Prevalence of lactase persistent/non-persistent genotypes and milk consumption in a young population in north-west Russia
World J. Gastroenterol.
15
1849-1853
2009
Homo sapiens
Behrendt, M.; Polaina, J.; Naim, H.Y.
Structural hierarchy of regulatory elements in the folding and transport of an intestinal multidomain protein
J. Biol. Chem.
285
4143-4152
2010
Homo sapiens
Koek, W.; van Meurs, J.; van der Eerden, B.; Rivadeneira, F.; Zillikens, M.; Hofman, A.; Obermayer-Pietsch, B.; Lips, P.; Pols, H.; Uitterlinden, A.; van Leeuwen, J.
The T-13910C polymorphism in the lactase phlorizin hydrolase gene is associated with differences in serum calcium levels and calcium intake
J. Bone Miner. Res.
25
1980-1987
2010
Homo sapiens
Ingram, C.J.; Raga, T.O.; Tarekegn, A.; Browning, S.L.; Elamin, M.F.; Bekele, E.; Thomas, M.G.; Weale, M.E.; Bradman, N.; Swallow, D.M.
Multiple rare variants as a cause of a common phenotype: several different lactase persistence associated alleles in a single ethnic group
J. Mol. Evol.
69
579-588
2009
BRENDA: Homo sapiens
Textmining: Mammalia
Khabarova, Y.; Torniainen, S.; Savilahti, E.; Isokoski, M.; Mattila, K.; Jaervelae, I.
The -13914G>A variant upstream of the lactase gene (LCT) is associated with lactase persistence/non-persistence
Scand. J. Clin. Lab. Invest.
70
354-357
2010
Homo sapiens
Stano, J.; Siekel, P.; Neubert, K.; Micieta, K.
Study of gherkin lactase in cell culture and in seedlings
Acta Histochem.
113
631-635
2011
Cucumis anguria
Kuchay, R.A.; Thapa, B.R.; Mahmood, A.; Mahmood, S.
Effect of C/T -13910 cis-acting regulatory variant on expression and activity of lactase in Indian children and its implication for early genetic screening of adult-type hypolactasia
Clin. Chim. Acta
412
1924-1930
2011
Homo sapiens
Kim, G.E.; Lee, J.H.; Jung, S.H.; Seo, E.S.; Jin, S.D.; Kim, G.J.; Cha, J.; Kim, E.J.; Park, K.D.; Kim, D.
Enzymatic synthesis and characterization of hydroquinone galactoside using Kluyveromyces lactis lactase
J. Agric. Food Chem.
58
9492-9497
2010
Kluyveromyces lactis, Thermus sp., Niallia circulans, Aspergillus oryzae
Naz, S.; Siddiqi, R.; Dew, T.P.; Williamson, G.
Epigallocatechin-3-gallate inhibits lactase but is alleviated by salivary proline-rich proteins
J. Agric. Food Chem.
59
2734-2738
2011
BRENDA: Rattus norvegicus
Textmining: Camellia sinensis
Nguyen, T.T.; Jung, S.J.; Kang, H.K.; Kim, Y.M.; Moon, Y.H.; Kim, M.; Kim, D.
Production of rubusoside from stevioside by using a thermostable lactase from Thermus thermophilus and solubility enhancement of liquiritin and teniposide
Enzyme Microb. Technol.
64-65
38-43
2014
Thermus thermophilus (Q8GEB4), Thermus thermophilus, Thermus, Escherichia coli, Camellia sinensis
Zhou, J.; Chen, Y.; Wang, Y.; Gao, X.; Qu, D.; Liu, C.
A comparative study on the metabolism of Epimedium koreanum nakai-prenylated flavonoids in rats by an intestinal enzyme (lactase phlorizin hydrolase) and intestinal flora
Molecules
19
177-203
2014
Rattus norvegicus
Zou, S.; He, X.; Liu, Y.; Chen, D.; Luo, Y.; Huang, K.; Zhang, W.; Xu, W.
Toxicological evaluation of lactase derived from recombinant Pichia pastoris
PLoS ONE
9
e106470
2014
BRENDA: Aspergillus oryzae
Textmining: Homo sapiens, Komagataella pastoris, Mus musculus, Mus sp., Rattus
Diekmann, L.; Behrendt, M.; Amiri, M.; Naim, H.Y.
Structural determinants for transport of lactase phlorizin-hydrolase in the early secretory pathway as a multi-domain membrane glycoprotein
Biochim. Biophys. Acta
1861
3119-3128
2017
Homo sapiens (P09848)
Suzuki, T.; Mochizuki, K.; Goda, T.
Thyroid and glucocorticoid hormones induce expression of lactase-phlorizin hydrolase gene in CDX-2/HNF-1alpha co-transfected IEC-6 cells
J. Nutr. Sci. Vitaminol.
60
321-327
2015
Rattus norvegicus (Q02401)
Diekmann, L.; Behrendt, M.; Amiri, M.; Naim, H.Y.
Structural determinants for transport of lactase phlorizin-hydrolase in the early secretory pathway as a multi-domain membrane glycoprotein
Biochim. Biophys. Acta Gen. Subj.
1861
3119-3128
2017
Homo sapiens (P09848)
Neu, J; Crim, WN; Sadowski, JA
Comparison of detergent versus protease solubilized rat intestinal lactase.
Enzyme
32
133-41
1984
Rattus, Homo sapiens
Sugawara, A; Horiguchi, H; Yoshikawa, J
Identification and characterization of proteinase B as an unstable factor for neutral lactase in the enzyme preparation from Kluyveromyces lactis.
J Biosci Bioeng
2020
Bos taurus, Kluyveromyces lactis, Saccharomyces cerevisiae
Kaur, G; Kaur, J; Mittal, N; Nath Sanyal, S
The effect of prostaglandin synthase inhibitor, aspirin on the rat intestinal membrane structure and function.
Nutr Hosp
25
290-298
2010
Rattus
Quaroni, A; Nichols, BL; Quaroni, E; Hurst, K; Herrera, L; Weiser, MM; Hamilton, SR
Expression and different polarity of aminopeptidase N in normal human colonic mucosa and colonic tumors.
Int J Cancer
51
404-11
1992
Homo sapiens
Dauncey, MJ; Ingram, DL
Alteration of lactase and aminopeptidase N expression in porcine enterocytes by energy intake and environment.
Q J Exp Physiol
71
443-9
1986
Sus scrofa, Suidae, Metazoa
Pemberton, PW; Lobley, RW; Sørensen, SH; Batt, RM
An aminopeptidase N deficiency in dog small intestine.
Res Vet Sci
63
133-8
0
Canis lupus familiaris
Fleming, WL; Neill, JM
STUDIES ON BACTERIAL ENZYMES : V. THE CARBOHYDRASES AND LIPASE OF THE WELCH BACILLUS.
J Exp Med
45
947-959
1927
Bacillus
Lowenstein, L; Fleming, WL; Neill, JM
STUDIES ON BACTERIAL ENZYMES : VII. LACTASE AND LIPASE OF THE COLON BACILLUS.
J Exp Med
49
475-479
1929
Bacillus, Bacilli
Bobkova, ED; Iushchuk, ND; Shalygina, NB
[Determination of the activity of lactase, maltase and alkaline phosphatase in the mucosa of the small intestine of healthy persons]
Lab Delo
160-2
1975
Homo sapiens
Lücking, T; Wenner, J
[Intestinal disaccharidase and alkaline phosphatase activities of jejunal biopsies in small bowel diseases of children (author's transl)]
Eur J Pediatr
121
263-77
1976
Homo sapiens
Mahmood, S; Babbar, HS; Mahmood, A
Temperature induced changes in brush border lactase and alkaline phosphatase activities of developing rat intestine.
Indian J Exp Biol
24
760-2
1986
Rattus
Toofanian, F
Intestinal disaccharidase and alkaline phosphatase activities in experimental rabbit mucoid enteropathy.
Lab Anim Sci
35
624-6
1985
Metazoa
Welsh, JD; Russell, LC; Walker, AW
Changes in intestinal lactase and alkaline phosphatase activity levels with age in the baboon (Papio papio).
Gastroenterology
66
993-7
1974
Papio anubis
Yeh, KY
Small intestine of artificially reared rat pups: weight gain and changes in alkaline phosphatase, lactase and sucrase activities during development.
J Nutr
113
1489-95
1983
Rattus
O'Grady, JG; Stevens, FM; Keane, R; Cryan, EM; Egan-Mitchell, B; McNicholl, B; McCarthy, CF; Fottrell, PF
Intestinal lactase, sucrase, and alkaline phosphatase in 373 patients with coeliac disease.
J Clin Pathol
37
298-301
1984
Homo sapiens
Majumdar, AP
Effects of hydrocortisone and pentagastrin on the activity of intestinal disaccharidases and alkaline phosphatase in weanling rats.
Scand J Gastroenterol
16
177-82
1981
Rattus
Rebolledo-Varela, E; Fernández-Otero, PM
[Effect of various fish meals on disaccharidases and alkaline phosphatase of the small intestine in rats]
Rev Esp Fisiol
38
321-5
1982
Calceolaria rupestris, Chondrichthyes, Metazoa
Wiesenfeld, P; Baldwin, J; Szepesi, B; Michaelis, OE
Effect of dietary carbohydrate and phenotype on sucrase, maltase, lactase, and alkaline phosphatase specific activity in SHR/N-cp rat.
Proc Soc Exp Biol Med
202
338-44
1993
Rattus, Zea mays subsp. mays
Maliś, F; Fric, P; Stépánková, R; Kruml, J
Digestive enzymes of the mucosa of the small intestine and trypsin and chymotrypsin proteolytic activity of the intestinal contents of germ-free, monocontaminated and conventional rabbits.
Acta Univ Carol Med Monogr
119-23
1977
Oryctolagus cuniculus, Caecum
Antonowicz, I; Lebenthal, E
Developmental pattern of small intestinal enterokinase and disaccharidase activities in the human fetus.
Gastroenterology
72
1299-303
1977
Homo sapiens
Niessen, KH; Sayer, T; Schunder, E
[The influence of orally applicable antibiotics on the activities of human enterokinase and disaccharidases (author's transl)]
Arzneimittelforschung
26
1216-21
1976
Homo sapiens
Zhang, P; Sawicki, V; Lewis, A; Hanson, L; Nuijens, JH; Neville, MC
Human lactoferrin in the milk of transgenic mice increases intestinal growth in ten-day-old suckling neonates.
Adv Exp Med Biol
501
107-13
2001
Indicator, Homo sapiens, Mus musculus, Mus sp., Rattus
Kendall, K; Jumawan, J; Koldovský, O
Development of jejunoileal differences of activity of lactase, sucrase and acid beta-galactosidase in isografts of fetal rat intestine.
Biol Neonate
36
206-14
1979
Rattus
Raul, F; Simon, PM; Kedinger, M; Grenier, JF; Haffen, K
Sucrase and lactase synthesis in suckling rat intestine in response to substrate administration.
Biol Neonate
33
100-5
1978
Rattus
Shinder, DA; Usmanova, OD; Rakhimov, KR
[Changes in the saccharase and lactase activities of the small intestine in suckling rats prematurely weaned from the nursing dam]
Fiziol Zh SSSR Im I M Sechenova
78
53-8
1992
Rattus
Yokota, K; Oda, S; Takesue, S; Takesue, Y
Intestinal disaccharidases in the house musk shrew, Suncus murinus: occurrence of sucrase deficiency.
Comp Biochem Physiol B
103
629-34
1992
Soricidae
Yeh, KY; Yeh, M; Montgomery, RK; Grand, RJ; Holt, PR
Cortisone and thyroxine modulate intestinal lactase and sucrase mRNA levels and activities in the suckling rat.
Biochem Biophys Res Commun
180
174-80
1991
Rattus
Flores, CA; Bezerra, J; Bustamante, SA; Goda, T; MacDonald, MP; Kaplan, ML; Koldovský, O
Age-related changes in sucrase and lactase activity in the small intestine of 3- and 10-week-old obese mice (C57BL/6Jobob).
J Am Coll Nutr
9
255-60
1990
Mus sp.
Turakulov, JC; Rakhimov, KR; Karimova, SF; Kuchkarova, LS
Postnatal development of pancreatic alpha-amylase and intestinal saccharase and lactase in rat sucklings as related to thyroid function of mothers.
Endocrinol Exp
23
217-27
1989
Rattus
Flores, CA; Bezerra, J; Goda, T; Bustamante, S; MacDonald, MP; Kaplan, M; Koldovský, O
Effect of a high-dextrose diet on sucrase and lactase activity in jejunum of obese mice (C57BL/6J obob).
J Am Coll Nutr
5
565-75
1986
Metazoa, Mus sp.
Goda, T; Bustamante, S; Koldovský,
Dietary regulation of intestinal lactase and sucrase in adult rats: quantitative comparison of effect of lactose and sucrose.
J Pediatr Gastroenterol Nutr
4
998-1008
1985
Rattus
Rommel, K; Böhmer, R
Influence of secretin and cholecystokinin on maltase, sucrase and lactase in the jejunum of the rat.
Digestion
11
194-8
1974
Rattus
Manners, MJ; Stevens, JA
Changes from birth to maturity in the pattern of distribution of lactase and sucrase activity in the mucosa of the small intestine of pigs.
Br J Nutr
28
113-27
1972
Suidae
Stevens, JA; Kidder, DE
The distribution of trehalase, sucrase, -amylase, glucoamylase and lactase ( -galactosidase) along the small intestine of five pigs.
Br J Nutr
28
129-37
1972
Suidae
Yamada, K; Goda, T; Bustamante, S; Koldovský, O
Different effect of starvation on activity of sucrase and lactase in rat jejunoileum.
Am J Physiol
244
G449-55
1983
Rattus
Boyle, JT; Celano, P; Koldovský, O
Demonstration of a difference in expression of maximal lactase and sucrase activity along the villus in the adult rat jejunum.
Gastroenterology
79
503-7
1980
Rattus
Yamada, K; Bustmante, S; Koldovský, O
Dietary-induced rapid increase of rat jejunal sucrase and lactase activity in all regions of the villus.
FEBS Lett
129
89-92
1981
Rattus
Treem, WR; Ahsan, N; Sullivan, B; Rossi, T; Holmes, R; Fitzgerald, J; Proujansky, R; Hyams, J
Evaluation of liquid yeast-derived sucrase enzyme replacement in patients with sucrase-isomaltase deficiency.
Gastroenterology
105
1061-8
1993
Saccharomyces cerevisiae
Hecht, A; Torbey, CF; Korsmo, HA; Olsen, WA
Regulation of sucrase and lactase in developing rats: role of nuclear factors that bind to two gene regulatory elements.
Gastroenterology
112
803-12
1997
Rattus, Metazoa
Lee, MF; Russell, RM; Montgomery, RK; Krasinski, SD
Total intestinal lactase and sucrase activities are reduced in aged rats.
J Nutr
127
1382-7
1997
Metazoa, Rattus
Courtois, P; Meuris, S; Sener, A; Malaisse, WJ; Scott, FW
Invertase, maltase, lactase, and peroxidase activities in duodenum of BB rats.
Endocrine
19
293-300
2002
Homo sapiens, Rattus, Saccharomyces cerevisiae
Fukushima, A; Goda, T; Motohashi, Y; Sakuma, K
The specific expression patterns of lactase, sucrase and calbindin-D9k in weaning rats are regulated at the transcriptional level.
J Nutr Sci Vitaminol (Tokyo)
50
265-71
2004
Rattus
Leforestier, G; Blais, A; Blachier, F; Marsset-Baglieri, A; Davila-Gay, AM; Perrin, E; Tomé, D
Effects of galacto-oligosaccharide ingestion on the mucosa-associated mucins and sucrase activity in the small intestine of mice.
Eur J Nutr
2009
Mus sp., Metazoa
Khoshoo, V; Bhan, MK; Jain, R; Jayashree, S; Bhandari, N; Sazawal, S; Mathur, M
Intestinal glucoamylase & other disaccharidases in children with protracted diarrhoea.
Indian J Med Res
92
1-4
1990
Homo sapiens
Karnsakul, W; Luginbuehl, U; Hahn, D; Sterchi, E; Avery, S; Sen, P; Swallow, D; Nichols, B
Disaccharidase activities in dyspeptic children: biochemical and molecular investigations of maltase-glucoamylase activity.
J Pediatr Gastroenterol Nutr
35
551-6
2002
Homo sapiens
Mohamed, SA; Fahmy, AS; Salah, HA
Disaccharidase activities in camel small intestine: biochemical investigations of maltase-glucoamylase activity.
Comp Biochem Physiol B Biochem Mol Biol
146
124-30
2007
Camelus bactrianus
Keller, P; Zwicker, E; Mantei, N; Semenza, G
The levels of lactase and of sucrase-isomaltase along the rabbit small intestine are regulated both at the mRNA level and post-translationally.
FEBS Lett
313
265-9
1992
Oryctolagus cuniculus
Yeh, KY; Du, FW; Holt, PR
Endogenous corticosterone rather than dietary sucrose as a modulator for intestinal sucrase activity in artificially reared rat pups.
J Nutr
116
1334-42
1986
Rattus
Harms, HK; Bertele-Harms, RM; Bruer-Kleis, D
Enzyme-substitution therapy with the yeast Saccharomyces cerevisiae in congenital sucrase-isomaltase deficiency.
N Engl J Med
316
1306-9
1987
Saccharomyces cerevisiae
Bochenek, WJ; Narczewska, B; Grzebieluch, M
Effect of massive proximal small bowel resection on intestinal sucrase and lactase activity in the rat.
Digestion
9
224-30
1973
Rattus
Lojda, Z; SmÃdová, J; KolÃnská, J; Kramal, J
A comparative study of lactase and sucrase-isomaltase activities and immunoreactivities in jejunal biopsies of patients suffering from the malabsorption syndrome.
Histochem J
16
373-6
1984
Homo sapiens
Dudley, MA; Hachey, DL; Quaroni, A; Hutchens, TW; Nichols, BL; Rosenberger, J; Perkinson, JS; Cook, G; Reeds, PJ
In vivo sucrase-isomaltase and lactase-phlorizin hydrolase turnover in the fed adult rat.
J Biol Chem
268
13609-16
1993
Rattus
Jumawan, J; Celano, P; Horowitz, C; Lau, H; Koldovsky, O
Effect of cortisone or L-triiodothyronine administration to pregnant rats on the activity of fetal intestinal disaccharidases and lysosomal acid beta-galactosidase.
Biol Neonate
32
211-7
1977
Rattus
Corazza, GR; Benati, G; Sorge, M; Strocchi, A; Calza, G; Gasbarrini, G
beta-Galactosidase from Aspergillus niger in adult lactose malabsorption: a double-blind crossover study.
Aliment Pharmacol Ther
6
61-6
1992
Aspergillus niger
Marteau, P; Flourie, B; Pochart, P; Chastang, C; Desjeux, JF; Rambaud, JC
Effect of the microbial lactase (EC 3.2.1.23) activity in yoghurt on the intestinal absorption of lactose: an in vivo study in lactase-deficient humans.
Br J Nutr
64
71-9
1990
Homo sapiens
Dean, AM; Dykhuizen, DE; Hartl, DL
Fitness effects of amino acid replacements in the beta-galactosidase of Escherichia coli.
Mol Biol Evol
5
469-85
1988
Indicator
Asp, NG; Dahlqvist, A; Koldovský, O
Human small-intestinal beta-galactosidases. Separation and characterization of one lactase and one hetero beta-galactosidase.
Biochem J
114
351-9
1969
Homo sapiens
Mozdziak, PE; Pophal, S; Borwornpinyo, S; Petitte, JN
Transgenic chickens expressing beta-galactosidase hydrolyze lactose in the intestine.
J Nutr
133
3076-9
2003
Gallus gallus, Escherichia coli
Flood, MT; Kondo, M
Toxicity evaluation of a beta-galactosidase preparation produced by Penicillium multicolor.
Regul Toxicol Pharmacol
40
281-92
2004
Penicillium multicolor
Montalto, M; Nucera, G; Santoro, L; Curigliano, V; Vastola, M; Covino, M; Cuoco, L; Manna, R; Gasbarrini, A; Gasbarrini, G
Effect of exogenous beta-galactosidase in patients with lactose malabsorption and intolerance: a crossover double-blind placebo-controlled study.
Eur J Clin Nutr
59
489-93
2005
Kluyveromyces lactis
He, T; Priebe, MG; Vonk, RJ; Welling, GW
Identification of bacteria with beta-galactosidase activity in faeces from lactase non-persistent subjects.
FEMS Microbiol Ecol
54
463-9
2005
Bacteria
Macris, BJ; Markakis, P
Characterization of Extracellular beta-d-Galactosidase from Fusarium moniliforme Grown in Whey.
Appl Environ Microbiol
41
956-958
1981
Fusarium verticillioides
Champluvier, B; Francart, B; Rouxhet, PG
Co-immobilization by adhesion of beta-galactosidase in nonviable cells of Kluyveromyces lactis with Klebsiella oxytoca: Conversion of lactose into 2, 3-butanediol.
Biotechnol Bioeng
34
844-53
1989
Kluyveromyces lactis
DÃaz Regueira, SM; Lamas, MA; Fernández Otero, MP
Action of actinomycin D on glycosidase levels in the small intestine of hamsters.
Cytobios
66
121-5
1991
Cricetinae, Metazoa
Stewart, IM; Messer, M; Walcott, PJ; Gadiel, PA; Griffiths, M
Intestinal glycosidase activities in one adult and two suckling echidnas: absence of a neutral lactase (beta-D-galactosidase).
Aust J Biol Sci
36
139-46
1983
Tachyglossidae, animal
Ramaswamy, S; Radhakrishnan, AN
Lactase and phlorizin hydrolase from rabbit small intestine.
Indian J Biochem Biophys
12
199-203
1975
Oryctolagus cuniculus
Dudley, MA; Shulman, RJ; Reeds, PJ; Rosenberger, JN; Putman, M; Johnston, PK; Perkinson, JS; Nichols, BL
Developmental changes in lactase-phlorizin hydrolase precursor isoforms in the rat.
J Pediatr Gastroenterol Nutr
15
260-9
1992
Rattus, Metazoa, animal
Boll, W; Wagner, P; Mantei, N
Structure of the chromosomal gene and cDNAs coding for lactase-phlorizin hydrolase in humans with adult-type hypolactasia or persistence of lactase.
Am J Hum Genet
48
889-902
1991
Homo sapiens
Büller, HA; Van Wassenaer, AG; Raghavan, S; Montgomery, RK; Sybicki, MA; Grand, RJ
New insights into lactase and glycosylceramidase activities of rat lactase-phlorizin hydrolase.
Am J Physiol
257
G616-23
1989
Mammalia, Rattus
Castillo, RO; Kwong, LK; Reisenauer, AM; Tsuboi, KK
Human intestinal lactase-phlorizin hydrolase: isolation and preparation of a specific antiserum.
Biochem Biophys Res Commun
164
94-101
1989
Homo sapiens, Oryctolagus cuniculus, Rattus
Neele, AM; Einerhand, AW; Dekker, J; Büller, HA; Freund, JN; Verhave, M; Grand, RJ; Montgomery, RK
Verification of the lactase site of rat lactase-phlorizin hydrolase by site-directed mutagenesis.
Gastroenterology
109
1234-40
1995
Rattus, Oryctolagus cuniculus
Lacey, SW; Naim, HY; Magness, RR; Gething, MJ; Sambrook, JF
Expression of lactase-phlorizin hydrolase in sheep is regulated at the RNA level.
Biochem J
302 ( Pt 3)
929-35
1994
Ovis aries
Olsen, WA; Li, BU; Lloyd, M; Korsmo, H
Heterogeneity of intestinal lactase activity in children: relationship to lactase-phlorizin hydrolase messenger RNA abundance.
Pediatr Res
39
877-81
1996
Homo sapiens, Mammalia
Baffour-Awuah, NY; Delemarre, E; Fujiwara, Y; Heijmans, J; Boerwinkel, D; Algra, S; Fialkovich, JJ; Islam, S; Bosse, T; Grand, RJ; Krasinski, SD; Montgomery, RK
Characterization of expression in mice of a transgene containing 3.3 kb of the human lactase-phlorizin hydrolase (LPH) 5' flanking sequence.
Dig Dis Sci
56
59-69
2011
Homo sapiens, Mus musculus
Ameen, NA; Ardito, T; Kashgarian, M; Marino, CR
A unique subset of rat and human intestinal villus cells express the cystic fibrosis transmembrane conductance regulator.
Gastroenterology
108
1016-23
1995
Homo sapiens, Rattus
Shi, J; Li, Y; Zhou, X; Zhang, Q; Ye, X; Wu, Z; Jiang, X; Yu, H; Shao, L; Ai, JW; Zhang, H; Xu, B; Sun, F; Zhang, W
Lactate dehydrogenase and susceptibility to deterioration of mild COVID-19 patients: a multicenter nested case-control study.
BMC Med
18
168
2020
Homo sapiens, Severe acute respiratory syndrome coronavirus 2
Păsculescu, G; Faur, A; Dorca, N; Toma, C; Ghircoiaşu, T
[Study of the functional behavior of the enterochromaffin cell system after lactose loading in patients with intestinal lactase deficiency]
Rev Med Interna Neurol Psihiatr Neurochir Dermatovenerol Med Interna
29
163-70
0
Homo sapiens
Lojda, Z
Suitability of the azocoupling reaction with 1-naphthyl-beta-D-glucoside for the histochemical demonstration of lactase (lactase-beta-glucosidase complex) in human enterobiopsies.
Histochemistry
43
349-53
1975
Homo sapiens
Bampoe, V; Sapsford, RJ; Avigad, S; Shiner, M
Lactase degradation by human enteric bacteria.
Lancet
2
125-7
1979
Bacteria, Homo sapiens, Saccharomyces cerevisiae
ChiÅŸu, A; Grigorescu-Sido, P; Lazar-Garoiu, F; BicleÅŸanu, A
[Lactase deficiency in children with secondary milk intolerance]
Rev Pediatr Obstet Ginecol Pediatr
27
157-62
0
Homo sapiens
Kim, KI; Benevenga, NJ; Grummer, RH
Lactase activity and VFA production in the cecum and colon of pigs fed a corn-soy or 40% whey diet.
J Anim Sci
46
1648-57
1978
Suidae
Malo, C; Ménard, D
Opposite effects of one and three injections of cortisone or thyroxine on intestinal lactase activity in suckling mice.
Experientia
35
493-4
1979
Mus sp., Metazoa
Kim, KI; Benevenga, NJ; Grummer, RH
In vitro measurement of the lactase activity and the fermentation products of lactose in the cecal and colonic contents of rats fed a control or 30% lactose diet.
J Nutr
109
856-63
1979
Rattus
Lev, R; Bender, MS; Appleton, HD
The biochemical and histochemical demonstration of lactase induction in fetal rat intestine by intra-amniotic injection of lactose.
Histochemistry
61
255-62
1979
Rattus
Cousineau, J; Green, JR
Brush-border membrane lactase: purification and kinetic analysis of two forms of the enzyme from the proximal and distal small intestine of suckling rats [proceedings]
Biochem Soc Trans
7
961-2
1979
Rattus
Potier, M; Guay, P; Lamothe, P; Bousquet, D; Dallaire, L; Melançon, SB
Origin and developmental patterns of lactase and other glycosidases in sheep amniotic and allantoic fluid.
J Reprod Fertil
57
49-57
1979
Ovis aries
Guiraldes, E; Sanhueza, P; Palma, R; Orrego, H
Relationship between changes in lactase activity and monosaccharide uptake in the small intestine of the rat during development.
Acta Physiol Lat Am
29
229-37
1979
Rattus
Ekstrom, KE; Benevenga, NJ; Grummer, RH
Effects of diets containing dried whey on the lactase activity of the small intestinal mucosa and the contents of the small intestine and cecum of the pig.
J Nutr
105
851-60
1975
Sus scrofa, Suidae
Hall, BG
Number of mutations required to evolve a new lactase function in Escherichia coli.
J Bacteriol
129
540-3
1977
Escherichia coli
Aumaitre, A; Fevrier, C; Dewulf, H
[Influence of dietary lactose on the development of lactase activity in the digestive tract of the pig]
C R Acad Sci Hebd Seances Acad Sci D
284
2135-8
1977
Sus scrofa, Suidae
Rodić, S; Durić, DS; Nesović, M
[Activity of intestinal lactase in patients with hypothyroidism]
Srp Arh Celok Lek
105
21-8
1977
Homo sapiens
Green, JR; Hauri, HP
Lactase enzymes in the intestinal brush border membrane of the suckling rat. A second enzyme restricted to ileum.
FEBS Lett
84
233-5
1977
Rattus
Cook, GC
Intestinal lactase status of adults in Papua New Guinea.
Ann Hum Biol
6
55-8
0
Guinea
Berg, NO; Dahlqvist, A; Lindberg, T
A boy with severe infantile gastrogen lactose intolerance and acquired lactase deficiency.
Acta Paediatr Scand
68
751-8
1979
Homo sapiens
Bakken, AF
Temproary intestinal lactase deficiency in light-treated jaundiced infants.
Acta Paediatr Scand
66
91-6
1977
Homo sapiens, Icterus
Bakken, AF
The application of the "Lojda" method for intestinal lactase in intestinal biopsies from jaundiced newborn infants.
Histochemistry
51
253-5
1977
Homo sapiens
Bakken, AF
[Diagnosis of intestinal lactase deficiency in children. Histochemical lactase determination in connection with results from the peroral lactose test and evaluation of intestinal mucosal structure]
Tidsskr Nor Laegeforen
97
414-6
1977
Homo sapiens
Celano, P; Jumawan, J; Koldovsky, O
Thyroxine-evoked decrease of jejunal lactase activity in adult rats.
Gastroenterology
73
425-7
1977
Rattus
Read, NW; Davies, RJ; Holdsworth, CD; Levin, RJ
Electrical assessment of functional lactase activity in conscious man.
Gut
18
640-3
1977
Homo sapiens
Flatz, G; Rotthauwe, HW
The human lactase polymorphism: physiology and genetics of lactose absorption and malabsorption.
Prog Med Genet
2
205-49
1977
Homo sapiens
Lifrak, IL; Lev, R; Loud, AV
Substrate-induced acceleration of lactase synthesis in fetal rat intestine.
Pediatr Res
10
100-2
1976
Rattus
Beck, IT; Da Costa, LR; Beck, M
Sugar absorption by small bowel biopsy samples from patients with primary lactase deficiency and with adult celiac disease.
Am J Dig Dis
21
946-52
1976
Homo sapiens, Rattus
Adlung, J; Kelch, L; Mischer, W; Grazikowske, H
[Diagnostics of lactose-malabsorption: value of tolerance tests and 14CO2 exhalation test in patients with and without lactase deficiency (author's transl)]
Med Klin
71
2017-22
1976
Homo sapiens
Chung, CM; Kong, YF
No evidence of lactase deficiency related to phototherapy of jaundiced infants.
N Engl J Med
295
1483
1976
Homo sapiens
Delmont, J; Sudaka, P; Loubière, M; Camous, JP; Rampal, P
[Intestinal comparative study of mucosa lactase activity with lactose tolerance test in 119 patients (author's transl)]
Biol Gastroenterol (Paris)
9
121-8
0
Homo sapiens
Ekstrom, KE; Benevenga, NJ; Grummer, RH
Changes in the intestinal lactase activity in the small intestine of two breeds of swine from birth to 6 weeks of age.
J Nutr
105
1032-8
1975
Metazoa, Suidae, Sus scrofa
Blum, AL; Haemmerli, UP; Lorenz-Meyer, H
Is phlorizin or its aglycon the inhibitor of intestinal glucose transport? A study in normal and lactase deficient man.
Eur J Clin Invest
5
285-8
1975
Homo sapiens
Cook, GC; al-Torki, MT
High intestinal lactase concentrations in adult Arbs in Saudi Arabia.
Br Med J
3
135-6
1975
Arabia, Homo sapiens, Colotis
Kobayashi, A; Kawai, S; Obe, Y; Nagashima, Y
Effects of dietary lactose and lactase preparation on the intestinal absorption of calcium and magnesium in normal infants.
Am J Clin Nutr
28
681-3
1975
Homo sapiens
Mahoney, RR; Nickerson, TA; Whitaker, JR
Selection of strain, growth conditions, and extraction procedures for optimum production of lactase from Kluyveromyces fragilis.
J Dairy Sci
58
1620-9
1975
Kluyveromyces marxianus, Saccharomyces cerevisiae, Karaftohelix fragilis
Bakken, AF
Letter: Intestinal lactase deficiency as a factor in the diarrhea of light-treated jaundiced infants.
N Engl J Med
294
615
1976
Homo sapiens
Ekstrom, KE; Grummer, RH; Benevenga, NJ
Effects of a diet containing 40% dried whey on the performance and lactase activities in the small intestine and cecum of Hampshire and Chester White pigs.
J Anim Sci
42
106-13
1976
Suidae
Shinohara, H; Goda, T; Takase, S
Decrease of lactase activity in the small intestine of jejunum-bypassed rats.
J Nutr Sci Vitaminol (Tokyo)
38
365-74
1992
Rattus, Metazoa
Collares, EF
[Comparative study of the gastric emptying of disaccharides and their respective monosaccharides in rats with ontogenic lactase deficiency]
Arq Gastroenterol
29
142-6
0
Rattus
Rings, EH; de Boer, PA; Moorman, AF; van Beers, EH; Dekker, J; Montgomery, RK; Grand, RJ; Büller, HA
Lactase gene expression during early development of rat small intestine.
Gastroenterology
103
1154-61
1992
Rattus
Rossi, M; Maiuri, L; Russomanno, C; Auricchio, S
In vitro biosynthesis of lactase in preweaning and adult rabbit.
FEBS Lett
313
260-4
1992
Oryctolagus cuniculus, Metazoa
Maiuri, L; Rossi, M; Raia, V; D'Auria, S; Swallow, D; Quaroni, A; Auricchio, S
Patchy expression of lactase protein in adult rabbit and rat intestine.
Gastroenterology
103
1739-46
1992
Oryctolagus cuniculus, Rattus, Homo sapiens, Metazoa
Aragón, JJ; Fernández-Mayoralas, A; Jiménez-Barbero, J; MartÃn-Lomas, M; Rivera-Sagredo, A; Villanueva, D
Evaluation of rat intestinal lactase in vivo with 4-galactosylxylose.
Clin Chim Acta
210
221-6
1992
Rattus
Rakhimov, KR; Shinder, DA; Usmanova, OD
[Delay in the natural repression of lactase activity in prematurely weaned rats is connected with change in their thyroid status]
Dokl Akad Nauk
325
1077-80
1992
Rattus
Villa, M; Ménard, D; Semenza, G; Mantei, N
The expression of lactase enzymatic activity and mRNA in human fetal jejunum. Effect of organ culture and of treatment with hydrocortisone.
FEBS Lett
301
202-6
1992
Homo sapiens
Bayer, M; Broulik, P; Sedlackova, M
Calcium metabolism in children with lactase deficiency.
N Z Med J
105
181
1992
Homo sapiens
Shulman, RJ; Tivey, DR; Sunitha, I; Dudley, MA; Henning, SJ
Effect of oral insulin on lactase activity, mRNA, and posttranscriptional processing in the newborn pig.
J Pediatr Gastroenterol Nutr
14
166-72
1992
Sus scrofa, Homo sapiens
Duluc, I; Galluser, M; Raul, F; Freund, JN
Dietary control of the lactase mRNA distribution along the rat small intestine.
Am J Physiol
262
G954-61
1992
Rattus, Metazoa
Maiuri, L; Raia, V; Potter, J; Swallow, D; Ho, MW; Fiocca, R; Finzi, G; Cornaggia, M; Capella, C; Quaroni, A
Mosaic pattern of lactase expression by villous enterocytes in human adult-type hypolactasia.
Gastroenterology
100
359-69
1991
Homo sapiens, Areas
Escher, JC; de Koning, ND; van Engen, CG; Arora, S; Büller, HA; Montgomery, RK; Grand, RJ
Molecular basis of lactase levels in adult humans.
J Clin Invest
89
480-3
1992
Homo sapiens
Cohen, L
Lactase deficiency: helping patients cope.
J Pract Nurs
41
59-61
1991
Homo sapiens
Slemenda, CW; Christian, JC; Hui, S; Fitzgerald, J; Johnston, CC
No evidence for an effect of lactase deficiency on bone mass in pre- or postmenopausal women.
J Bone Miner Res
6
1367-71
1991
Homo sapiens
Collares, EF; Belangero, VM; Da-Silva, PE
Gastric emptying of maltose, sucrose, lactose and lactulose in rats with ontogenic lactase deficiency.
Braz J Med Biol Res
24
539-42
1991
Rattus, Homo sapiens
Freund, JN; Duluc, I; Raul, F
Lactase expression is controlled differently in the jejunum and ileum during development in rats.
Gastroenterology
100
388-94
1991
Rattus
Pietschmann, P; Knoflach, P; Wolosczczuk, W
Increased serum osteocalcin levels in patients with lactase deficiency.
Am J Gastroenterol
86
72-4
1991
Homo sapiens
Yeh, KY; Yeh, M; Holt, PR
Intestinal lactase expression and epithelial cell transit in hormone-treated suckling rats.
Am J Physiol
260
G379-84
1991
Rattus, animal
Kelly, D; King, TP; McFadyen, M; Travis, AJ
Effect of lactation on the decline of brush border lactase activity in neonatal pigs.
Gut
32
386-92
1991
Suidae, Metazoa
Tivey, DR; Hilton, KJ; Dauncey, MJ
Compensatory increase in lactase expression by enterocytes of neonatal pigs on a low energy intake.
Exp Physiol
76
285-8
1991
Suidae
Yeh, KY; Yeh, M; Pan, PC; Holt, PR
Posttranslational cleavage of rat intestinal lactase occurs at the luminal side of the brush border membrane.
Gastroenterology
101
312-8
1991
Rattus
Gräbnitz, F; Seiss, M; Rücknagel, KP; Staudenbauer, WL
Structure of the beta-glucosidase gene bglA of Clostridium thermocellum. Sequence analysis reveals a superfamily of cellulases and beta-glycosidases including human lactase/phlorizin hydrolase.
Eur J Biochem
200
301-9
1991
Acetivibrio thermocellus, archaebacterium, Escherichia coli, Homo sapiens, Saccharolobus solfataricus, Terminator
Freund, JN; Foltzer-Jourdainne, C; Duluc, I; Galluser, M; Gosse, F; Raul, F
Rat lactase activity and mRNA expression in relation to the thyroid and corticoid status.
Cell Mol Biol
37
463-6
1991
Rattus
Carlson, SJ; Rogers, RR; Lombard, KA
Effect of a lactase preparation on lactose content and osmolality of preterm and term infant formulas.
JPEN J Parenter Enteral Nutr
15
564-6
0
Homo sapiens
Smith, MW; James, PS; Collins, AJ
Galactose inhibits lactase expression by mouse jejunal enterocytes.
Biochim Biophys Acta
1051
109-11
1990
Mus musculus, Mus sp., Rattus
Schneider, RE; Corona, E; Rosales, F; Schneider, FE; Rodriguez, O; Pineda, O
Effect of temperature on the lactose hydrolytic capacity of a lactase derived from Kluyveromyces lactis.
Am J Clin Nutr
51
197-201
1990
Kluyveromyces lactis
Savidge, TC; Smith, MW; Kilshaw, PJ
Possible lymphocyte effects on lactase expression by mouse jejunal enterocytes.
Exp Physiol
75
111-3
1990
Heligmosomoides polygyrus, Mus musculus, Narcissus dubius
Tadesse, K
The effect of continued feeding of physiological amounts of lactose on the level of intestinal lactase and other disaccharidase enzyme activities in the rat.
Exp Physiol
75
231-8
1990
Rattus, Metazoa, Mammalia
Freund, JN; Duluc, I; Foltzer-Jourdainne, C; Gosse, F; Raul, F
Specific expression of lactase in the jejunum and colon during postnatal development and hormone treatments in the rat.
Biochem J
268
99-103
1990
Rattus
Thomas, S; Walker-Smith, JA; Senewiratne, B; Hjelm, M
Age dependency of the lactase persistence and lactase restriction phenotypes among children in Sri Lanka and Britain.
J Trop Pediatr
36
80-5
1990
Homo sapiens
Miller, JJ; McVeagh, P; Fleet, GH; Petocz, P; Brand, JC
Effect of yeast lactase enzyme on "colic" in infants fed human milk.
J Pediatr
117
261-3
1990
Saccharomyces cerevisiae, Homo sapiens
Quan, R; Santiago, NA; Tsuboi, KK; Gray, GM
Intestinal lactase. Shift in intracellular processing to altered, inactive species in the adult rat.
J Biol Chem
265
15882-8
1990
Rattus, Mammalia
Castillo, RO; Reisenauer, AM; Kwong, LK; Tsuboi, KK; Quan, R; Gray, GM
Intestinal lactase in the neonatal rat. Maturational changes in intracellular processing and brush-border degradation.
J Biol Chem
265
15889-93
1990
Rattus, insertion sequences, Metazoa, Santiago
Franková, Y; Zeman, J; Mejsnarová, B; Stloukalová, M; Pajerek, J
[Partial trisomy 1q25-1q32 in a boy with isolated lactase deficiency]
Cesk Pediatr
45
87-8
1990
Homo sapiens
Duluc, I; Freund, JN; Mantei, N; Raul, F
[Different expression of the mRNA detected by the cDNA for fetal rat lactase in the jejunum and colon]
Gastroenterol Clin Biol
14
635-40
1990
Rattus
Shimizu, K; Nose, O; Okada, S
The effect of thyroid hormone on the activities of lactase in the culture of fetal rat intestine.
Cell Biol Int Rep
14
1143-8
1990
Rattus
Quak, SH; Raman, GV; Low, PS; Wong, HB
Lactase insufficiency in Chinese children detected by oral milk and lactose challenge.
Ann Trop Paediatr
7
100-3
1987
Homo sapiens
Sebastio, G; Villa, M; Sartorio, R; Guzzetta, V; Poggi, V; Auricchio, S; Boll, W; Mantei, N; Semenza, G
Control of lactase in human adult-type hypolactasia and in weaning rabbits and rats.
Am J Hum Genet
45
489-97
1989
Homo sapiens, Mammalia, Metazoa, Oryctolagus cuniculus, Rattus
Smith, MW; Lloyd, S
Intestinal infection with Nematospiroides dubius selectively increases lactase expression by mouse jejunal enterocytes.
Clin Sci (Lond)
77
139-44
1989
Heligmosomoides polygyrus, Mus musculus, Mus sp.
Crisp, EA; Messer, M; Cowan, PE
Intestinal lactase (beta-galactosidase) and other disaccharidase activities of suckling and adult common brushtail possums, Trichosurus vulpecula (Marsupialia:Phalangeridae).
Reprod Fertil Dev
1
315-24
1989
Metazoa, Starmerella aceti, Trichosurus vulpecula
Olusanya, O; Olutiola, PO
Properties of lactase produced by enteropathogenic Escherichia coli from diarrhoeic children.
Afr J Med Med Sci
18
163-8
1989
Escherichia coli, Homo sapiens
Rujner, J; Korszyńska, D; Socha, J; Wozniewicz, B
[Gamma-glutamyl transpeptidase, lactase and maltase activity in the intestinal mucosa of children with chronic diarrhea]
Pol Tyg Lek
41
1176-9
1986
Homo sapiens
Cook, GC
Human intestinal lactase and Lamarckian evolution.
Lancet
2
1029
1988
Homo sapiens
Flatz, G; Henze, HJ; Palabiyikoglu, E; Dagalp, K; Türkkan, T
Distribution of the adult lactase phenotypes in Turkey.
Trop Geogr Med
38
255-8
1986
Meleagris gallopavo, Clinitrachus argentatus
Nsi-Emvo, E; Launay, JF; Raul, F
Improved purification of rat intestinal lactase.
Gen Physiol Biophys
5
53-9
1986
Rattus, Oryctolagus cuniculus
Hudson, DA; Smith, MW
Colchicine selectively inhibits lactase expression by rat enterocytes.
Biochem Pharmacol
35
3929-34
1986
Rattus
Hewitt, JE; Smith, MW
Thyroid hormone effects on lactase expression by rat enterocytes.
J Physiol
376
253-65
1986
Rattus, Metazoa
Vigorita, VJ; Lane, M; Suda, MK; Nelkin, M
Differences between lactase deficient and non-lactase deficient women with spinal osteoporosis.
Clin Orthop Relat Res
248-53
1987
Homo sapiens
Nsi Emvo, E; Launay, JF; Raul, F
Modulation by thyroxine of the amount of lactase protein in the jejunum of adult rats.
Enzyme
36
216-20
1986
Rattus, Metazoa
Mazzanti, R; Debnam, ES; Jenkins, WJ
Effect of chronic ethanol intake on lactase activity and active galactose absorption in rat small intestine.
Gut
28
56-60
1987
Rattus
Smith, MW; James, PS
Cellular origin of lactase decline in postweaned rats.
Biochim Biophys Acta
905
503-6
1987
Rattus
Muto, T
[Isolation and characterization of papain-digested lactase [I] and [II] from the rat small intestine]
Nippon Ika Daigaku Zasshi
54
509-18
1987
Rattus
Chang, MH; Hsu, HY; Chen, CJ; Lee, CH; Hsu, JY
Lactose malabsorption and small-intestinal lactase in normal Chinese children.
J Pediatr Gastroenterol Nutr
6
369-72
0
Homo sapiens
Jiang, TA
[Small intestinal mucosal morphology, lactase and lactose hydrolysis in children with diarrhea]
Zhonghua Yi Xue Za Zhi
67
499-502
1987
Homo sapiens
Leichter, J; Goda, T; Koldovsky, O
Dependency of lactose absorption on lactase activity in starved rats.
Can J Physiol Pharmacol
65
2287-90
1987
Rattus, Metazoa
Hiele, M; Ghoos, Y; Rutgeerts, P; Vantrappen, G; Carchon, H; Eggermont, E
13CO2 breath test using naturally 13C-enriched lactose for detection of lactase deficiency in patients with gastrointestinal symptoms.
J Lab Clin Med
112
193-200
1988
Homo sapiens
Crisp, EA; Messer, M; Shaughnessy, PD
Intestinal lactase and other disaccharidase activities of a suckling crabeater seal (Lobodon carcinophagus).
Comp Biochem Physiol B
90
371-4
1988
Lobodon carcinophaga
Smith, MW; Lloyd, S; James, PS
Testing the hypothesis that crypt cell hyperplasia inhibits lactase expression by mouse jejunal enterocytes.
Q J Exp Physiol
73
777-80
1988
Mus musculus, Heligmosomoides polygyrus
Dewit, O; Boudraa, G; Touhami, M; Desjeux, JF
Breath hydrogen test and stools characteristics after ingestion of milk and yogurt in malnourished children with chronic diarrhoea and lactase deficiency.
J Trop Pediatr
33
177-80
1987
Homo sapiens
Jodry, H; Griessen, M; Courvoisier, B; Fischer, J
[Incidence of lactase deficiency in patients with involution osteoporosis and in normal subjects. Its effect on the nutritional intake of calcium and phosphorus]
Schweiz Med Wochenschr
117
1736-41
1987
Homo sapiens
Brand, JC; Darnton-Hill, I
Lactase deficiency in Australian school children.
Med J Aust
145
318-22
1986
Homo sapiens
Rapellino, M; Borasio, P; Baldi, S; Coni, F; Oliaro, A; Libertucci, D; Ardissone, F
[Diagnostic contribution of the determination of CEA, pH, glucose and lactase dehydrogenase in the pleural fluid in patients with mesothelioma]
Minerva Med
78
317-9
1987
Homo sapiens
Swallow, DM; Potter, J; Green, F; Ho, MW
Preparation of a monoclonal antibody against human lactase.
J Immunol Methods
77
139-45
1985
Homo sapiens
Potter, J; Ho, MW; Bolton, H; Furth, AJ; Swallow, DM; Griffiths, B
Human lactase and the molecular basis of lactase persistence.
Biochem Genet
23
423-39
1985
Homo sapiens
Jonas, MM; Montgomery, RK; Grand, RJ
Intestinal lactase synthesis during postnatal development in the rat.
Pediatr Res
19
956-62
1985
Rattus, Metazoa
Yeh, KY; Holt, PR
Rat milk maintains intestinal lactase activity in rat pups whereas artificial formulas do not.
Pediatr Res
19
963-7
1985
Rattus, animal
Balanza, E; Taboada, G
The frequency of lactase phenotypes in Aymara children.
J Med Genet
22
128-30
1985
Homo sapiens
Lojda, Z; Jodl, J; Fric, P
[Morphology and histochemistry of the jejunal mucosa in patients with lactase deficiency]
Cesk Patol
10
10-7
1974
Homo sapiens
Lebenthal, E; Tsuboi, K; Kretchmer, N
Characterization of human intestinal lactase and hetero-beta-galactosidases of infants and adults.
Gastroenterology
67
1107-13
1974
Homo sapiens
Levyts'kyÄ, AP; Redchyts', PS
[Lactase activity of the mucous membrane of the small intestine of dogs with experimental pancreatitis]
Fiziol Zh
20
823-4
0
Canis lupus familiaris
Becker, A; Cerda, R; Delgado, P; Orrego-Matte, H; Navia, E
Letters: Lack of effect of rat milk on intestinal lactase activity in the postweaning rat.
Acta Physiol Lat Am
24
662-5
1974
Rattus
Hall, BG; Hartl, DL
Regulation of newly evolved enzymes. I. Selection of a novel lactase regulated by lactose in Escherichia coli.
Genetics
76
391-400
1974
Escherichia, Escherichia coli
Bishop, RF; Barnes, GL
Depression of lactase activity in the small intestine of infant rabbits by Candida albicans.
J Med Microbiol
7
259-63
1974
Candida albicans, Homo sapiens, Oryctolagus cuniculus
Lorenz-Meyer, H; Blum, A; Semenza, G
[Lactase phlorizin-hydrolase complex of the human small intestine]
Verh Dtsch Ges Inn Med
78
1413-8
1972
Homo sapiens
Leichter, J
Effect of dietary lactose on intestinal lactase activity in young rats.
J Nutr
103
392-6
1973
Rattus
Lebenthal, E; Sunshine, P; Kretchmer, N
Effect of prolonged nursing on the activity of intestinal lactase in rats.
Gastroenterology
64
1136-41
1973
Rattus
Gossrau, R
[Beta-glucosidase and lactase in the intestine of vertebrates]
Histochemie
35
143-51
1973
vertebrata
Cerf, M; Chariot, J; Fox, A; Debray, C
[Jejunal L-leucyl-beta-naphthylamidase activity in normal man and in patients with digestive disease. Comparison with jejunal lactase and maltase activities (author's transl)]
Arch Fr Mal App Dig
62
481-7
1973
Homo sapiens
Yeh, K; Moog, F
Intestinal lactase activity in the suckling rat: influence of hypophysectomy and thyroidectomy.
Science
183
77-9
1974
Rattus
Rosensweig, NS
Adult human milk intolerance and intestinal lactase deficiency. A review.
J Dairy Sci
52
585-7
1969
Homo sapiens
Broitman, SA
Gut lactase activity: decrease during Salmonella typhimurium infection in mice.
Proc Soc Exp Biol Med
136
1097-9
1971
Mus sp., Salmonella enterica subsp. enterica serovar Typhimurium
Hors-Cayla, MC; Rey, J
[Alpha-glucosidase and lactase activities of human intestinal cells in tissue culture]
C R Acad Sci Hebd Seances Acad Sci D
268
1653-6
1969
Homo sapiens
Swaminathan, N; Radhakrishnan, AN
Purification and properties of lactase from monkey kidney.
Biochim Biophys Acta
191
322-8
1969
Platyrrhini
Charney, M; McCracken, RD
Intestinal lactase deficiency in adult nonhuman primates: implications for selection pressures in man.
Soc Biol
18
416-21
1971
Primates, Homo sapiens
Bolin, TD; Pirola, RC; Davis, AE
Adaptation of intestinal lactase in the rat.
Gastroenterology
57
406-9
1969
Rattus
Paris, J; Gerard, A; Paris, JC; Delmotte, JS; Bonvarlet, P
[Lactase insufficiency in patients with gastroduodenal ulcer in the evolutive stage]
Lille Med
17
69-72
1972
Homo sapiens
Niessen, KH; Schmidt, K; Brügmann, G
[Lactase deficiency in children with cystic fibrosis of the pancreas (CFP)]
Klin Wochenschr
50
390-1
1972
Homo sapiens
Grigorescu-Sido, P; David, C; Lazăr-Garoiu, F
[Digestive parasitic diseases and lactase deficiency in children]
Pediatria (Bucur)
21
115-24
0
Homo sapiens
Erkelens, DW; Bouman, JG; Jansen, W
[Lactose intolerance and lactase deficiency in adult patients in Curacao]
Ned Tijdschr Geneeskd
116
1080-5
1972
Homo sapiens
Paris, J; Gerard, A; Paris, JC; Delmotte, JS; Bonvarlet, P
[Lactase insufficiency in patients with active gastro-duodenal ulcer]
Nouv Presse Med
1
198
1972
Homo sapiens
Gilat, T; Russo, S; Gelman-Malachi, E; Aldor, TA
Lactase in man: a nonadaptable enzyme.
Gastroenterology
62
1125-7
1972
Homo sapiens
Diwok, K; Hütter, HJ
[Significance of intestinal lactase in milk intolerance of gastrectomized patients]
Z Gesamte Inn Med
27
387-90
1972
Homo sapiens
McCracken, RD
Origins and implications of the distribution of adult lactase deficiency in human populations.
J Trop Pediatr Environ Child Health
17
7-10
1971
Homo sapiens
Jussila, J; Launiala, K; Gorbatow, O
Lactase deficiency and a lactose-free diet in patients with "unspecific abdominal complaints".
Acta Med Scand
186
217-22
1969
Homo sapiens
Welsh, JD
Isolated lactase deficiency in humans: report on 100 patients.
Medicine (Baltimore)
49
257-77
1970
Homo sapiens
Gouin, B; Duchier, J; Cerf, M; Marche, C; Debray, C
[Simultaneous study of lactase activity and lipid absorption in the intestinal mucosa in man. Application to various pathological states]
Presse Med
78
1619-23
1970
Homo sapiens
Bolin, TD; McKern, A; Davis, AE
The effect of diet on lactase activity in the rat.
Gastroenterology
60
432-7
1971
Rattus
Paris, J; Gerard, A; Paris, JC; Denoeux, JP
[Lactase insufficiency in gastrectomized patients. Critical study apropos of 50 cases]
Lille Med
16
387-92
1971
Homo sapiens
Alpers, DH; Gerber, JE
Monosaccharide inhibition of human intestinal lactase.
J Lab Clin Med
78
265-74
1971
Homo sapiens
Asp, NG; Dahlqvist, A
Multiplicity of intestinal beta-galactosidases. Contribution of each enzyme to the total lactase activity in normal and lactose-intolerant patients.
Acta Paediatr Scand
60
364-5
1971
Homo sapiens
Antonowicz, I; Reddy, V; Khaw, KT; Shwachman, H
Lactase deficiency in patients with cystic fibrosis.
Pediatrics
42
492-500
1968
Homo sapiens
Gray, GM; Santiago, NA; Colver, EH; Genel, M
Intestinal beta-galactosidases. II. Biochemical alteration in human lactase deficiency.
J Clin Invest
48
729-35
1969
Homo sapiens
Jussila, J; Gorbatow, O; Launiala, K
[Lactase deficiency in patients with non-specific abdominal symptoms]
Duodecim
85
410-6
1969
Homo sapiens
Weser, E; Rubin, W; Ross, L; Sleisenger, MH
Lactase deficiency in patients with the "irritable-colon syndrome".
N Engl J Med
273
1070-5
1965
Homo sapiens
Auricchio, S; Rubino, A; Tosi, R; Semenza, G; Landolt, M; Kistler, HJ; Prader, A
[The quantitative disaccharidase activity of the human small intestine and acquired lactase deficiency in adults]
Helv Med Acta
30
690-2
1963
Homo sapiens
Elliott, RB; Maxwell, GM
Predominance of lactase of small molecular size in duodenal and jejunal mucosa of Australian aboriginal children.
Aust J Exp Biol Med Sci
44
709-13
1966
Homo sapiens
Cook, GC
Lactase activity in newborn and infant Baganda.
Br Med J
1
527-30
1967
Homo sapiens
Nielsen, OH; Schiøtz, PO; Rasmussen, SN; Krasilnikoff, PA
Calcium absorption and acceptance of low-lactose milk among children with primary lactase deficiency.
J Pediatr Gastroenterol Nutr
3
219-23
1984
Homo sapiens
Raul, F; Noriega, R; Nsi-Emvo, E; Doffoel, M; Grenier, JF
Lactase activity is under hormonal control in the intestine of adult rat.
Gut
24
648-52
1983
Rattus
Besnier, MO; Bourlioux, P; Fourniat, J; Ducluzeau, R; Aumaitre, A
[Effect of yogurt ingestion on the intestinal lactase activity in axenic or holoxenic mice]
Ann Microbiol (Paris)
134A
219-30
0
Mus sp.
Paul, T; Flatz, G
Temporary depression of lactase activity by thyroxine in suckling rats.
Enzyme
30
54-8
1983
Rattus, Metazoa, Mammalia
Newcomer, AD; Park, HS; O'Brien, PC; McGill, DB
Response of patients with irritable bowel syndrome and lactase deficiency using unfermented acidophilus milk.
Am J Clin Nutr
38
257-63
1983
Homo sapiens
Becci, PJ; Gephart, LA; Re, TA
Subchronic feeding study in rats of immobilized lactase following in utero exposure.
J Appl Toxicol
3
80-2
1983
Rattus
Lifschitz, CH; Smith, EO; Garza, C
Delayed complete functional lactase sufficiency in breast-fed infants.
J Pediatr Gastroenterol Nutr
2
478-82
1983
Homo sapiens
Kraft, L; Hovi, T; Savilahti, E
Lack of protection from rotavirus infection in children with congenital intestinal lactase deficiency.
J Infect Dis
148
1166-7
1983
Homo sapiens, Rotavirus
Nsi-Emvo, E; Raul, F
Stimulation of lactase synthesis induced by starvation in the jejunum of adult rat.
Enzyme
31
45-9
1984
Rattus, animal
Goda, T; Bustamante, S; Thornburg, W; Koldovský, O
Dietary-induced increase in lactase activity and in immunoreactive lactase in adult rat jejunum.
Biochem J
221
261-3
1984
Rattus
Goda, T; Bustamante, S; Grimes, J; Koldovský, O
Dietary induced increase of lactase activity in adult rats is independent of adrenals.
Experientia
40
1287-8
1984
Rattus
Leichter, J; Goda, T; Bhandari, SD; Bustamante, S; Koldovský, O
Relation between dietary-induced increase of intestinal lactase activity and lactose digestion and absorption in adult rats.
Am J Physiol
247
G729-35
1984
Rattus
Roggero, P; Mangiaterra, V; Longoni, R; Lambri, A; Marenghi, L
[Effects of lactase administration in children with lactose malabsorption. Evaluation using the breath hydrogen test]
Minerva Pediatr
36
653-7
1984
Homo sapiens
Troncon, LE; de Oliveira, RB; Collares, EF; Padovan, W
Gastric emptying of lactose and glucose-galactose in patients with low intestinal lactase activity.
Arq Gastroenterol
20
8-12
0
Homo sapiens
Barr, RG; Hanley, J; Patterson, DK; Wooldridge, J
Breath hydrogen excretion in normal newborn infants in response to usual feeding patterns: evidence for "functional lactase insufficiency" beyond the first month of life.
J Pediatr
104
527-33
1984
Homo sapiens
AÄiub, AK
[Lactase activity of small intestine mucosa and intraduodenal digestion of proteins and polysaccharides in patients with milk intolerance]
Klin Med (Mosk)
62
90-2
1984
Homo sapiens
Skovbjerg, H; Gudmand-Høyer, E; Fenger, HJ
Immunoelectrophoretic studies on human small intestinal brush border proteins--amount of lactase protein in adult-type hypolactasia.
Gut
21
360-4
1980
Homo sapiens
Cook, GC; Nurse, GT
The intestinal lactase polymorphism in Papua New Guinea.
P N G Med J
23
141-5
1980
Guinea, Homo sapiens
Cochet, B; Griessen, M; Balant, L; Infante, F; Vallotton, MC; Bergoz, R
[Breath hydrogen for detecting lactase deficiency. II. Relation between intestinal lactase activity, breath hydrogen and blood glucose during lactose tolerance test in 73 adult patients (author's transl)]
Gastroenterol Clin Biol
5
29-36
1981
Homo sapiens
Whitington, PF
Effect of jaundice phototherapy on intestinal mucosal bilirubin concentration and lactase activity in the congenitally jaundiced Gunn Rat.
Pediatr Res
15
345-8
1981
Rattus, Metazoa
Bustamante, S; Gasparo, M; Kendall, K; Coates, P; Brown, S; Somawane, B; Koldovsky, O
Increased activity of rat intestinal lactase due to increased intake of alpha-saccharides (starch, sucrose) in isocaloric diets.
J Nutr
111
943-53
1981
Rattus
Howell, JN; Schockenhoff, T; Flatz, G
Population screening for the human adult lactase phenotypes with a multiple breath version of the breath hydrogen test.
Hum Genet
57
276-8
1981
Homo sapiens
Yamada, K; Bustamante, S; Koldovsky, O
Time- and dose-dependency of intestinal lactase activity in adult rat on starch intake.
Biochim Biophys Acta
676
108-12
1981
Rattus
Raab, W; Scharrer, E; Liebich, HG; Bernecker, H
[Developmental and nutritional changes of intestinal changes of intestinal lactase and maltase activities in the lamb]
Zentralbl Veterinarmed A
28
265-75
1981
Ovis aries
Jenkins, T; Gibney, SF; Nurse, GT; Penketh, RJ
Persistent high intestinal lactase activity in Papua New Guinea. Lactose absorption curves in two populations.
Ann Hum Biol
8
447-51
0
Guinea, Homo sapiens
Arnhold, RG; Perman, JA; Nurse, GT
Persistent high intestinal lactase activity in Papua New Guinea. The breath hydrogen test in a Sepik population.
Ann Hum Biol
8
481-4
0
Guinea
Neu, J; Masi, M; Stevenson, DK; Kwong, LK; Hurwitz, R; Sunshine, P
Effects of asphyxia and oral gentamicin on intestinal lactase in the suckling rat.
Pediatr Pharmacol (New York)
1
215-20
1981
Rattus
Boyle, JT; Kelly, K; Krulich, L; Koldovský, O
Site of thyroxine-evoked decrease of jejunal lactase in the rat.
Am J Physiol
243
G359-64
1982
Rattus
Rosenkranz, W; Hadorn, B; Müller, W; Heinz-Erian, P; Hensen, C; Flatz, G
Distribution of human adult lactase phenotypes in the population of Austria.
Hum Genet
62
158-61
1982
Homo sapiens
Felipoff, AL; RÃo, ME
Kinetic constants of lactase of the small intestine of growing rats fully recovered from protein depletion, in relation to dietary protein and lactose concentration.
J Nutr Sci Vitaminol (Tokyo)
28
477-82
1982
Rattus
Savilahti, E; Launiala, K; Kuitunen, P
Congenital lactase deficiency. A clinical study on 16 patients.
Arch Dis Child
58
246-52
1983
Homo sapiens
Similä, S; Kokkonen, J; Kouvalainen, K
Use of lactose-hydrolyzed human milk in congenital lactase deficiency.
J Pediatr
101
584-5
1982
Homo sapiens
Hyams, JS; Stafford, RJ; Grand, RJ; Watkins, JB
Correlation of lactose breath hydrogen test, intestinal morphology, and lactase activity in young children.
J Pediatr
97
609-12
1980
Homo sapiens
Hauri, HP; Sander, B; Naim, H
Induction of lactase biosynthesis in the human intestinal epithelial cell line Caco-2.
Eur J Biochem
219
539-46
1994
Homo sapiens
Goda, T; Yasutake, H; Suzuki, Y; Takase, S; Koldovský, O
Diet-induced changes in gene expression of lactase in rat jejunum.
Am J Physiol
268
G1066-73
1995
Rattus, Metazoa, Zea mays subsp. mays
Shinder, DA; Rakhimov, KR; Usmanova, OD
Delay in natural decline of lactase activity in the small intestine of prematurely weaned rats as related to changes in their thyroid status.
Comp Biochem Physiol A Physiol
111
453-9
1995
Rattus
Rings, EH; Grand, RJ; Büller, HA
Lactose intolerance and lactase deficiency in children.
Curr Opin Pediatr
6
562-7
1994
Homo sapiens
Boukamel, R; Freund, JN
The cis-element CE-LPH1 of the rat intestinal lactase gene promoter interacts in vitro with several nuclear factors present in endodermal tissues.
FEBS Lett
353
108-12
1994
Rattus
Maiuri, L; Rossi, M; Raia, V; Garipoli, V; Hughes, LA; Swallow, D; Norén, O; Sjöström, H; Auricchio, S
Mosaic regulation of lactase in human adult-type hypolactasia.
Gastroenterology
107
54-60
1994
Homo sapiens
Rings, EH; Krasinski, SD; van Beers, EH; Moorman, AF; Dekker, J; Montgomery, RK; Grand, RJ; Büller, HA
Restriction of lactase gene expression along the proximal-to-distal axis of rat small intestine occurs during postnatal development.
Gastroenterology
106
1223-32
1994
Rattus
Aleksić, D
[Disorders of lactase hydrolysis in patients with ulcerous colitis and irritable colon]
Srp Arh Celok Lek
121
1-3
0
Homo sapiens
Duluc, I; Jost, B; Freund, JN
Multiple levels of control of the stage- and region-specific expression of rat intestinal lactase.
J Cell Biol
123
1577-86
1993
Rattus, Metazoa
Rossi, M; Maiuri, L; Salvati, VM; Russomanno, C; Auricchio, S
Analysis of lactase processing in rabbit.
FEBS Lett
336
299-303
1993
Oryctolagus cuniculus
Ramakrishnan, S; Hartley, BS
Fermentation of lactose by yeast cells secreting recombinant fungal lactase.
Appl Environ Microbiol
59
4230-5
1993
Saccharomyces cerevisiae
Buchmiller, TL; Gregg, J; Rivera, FA; Diamond, JM; Fonkalsrud, EW
Effect of esophageal ligation on the development of fetal rabbit intestinal lactase.
J Pediatr Surg
28
1473-7
1993
Homo sapiens, Oryctolagus cuniculus
Rossi, M; Maiuri, L; Salvati, VM; Russomanno, C; Capparelli, R; Auricchio, S
In vitro biosynthesis of lactase in suckling and adult rabbits. Regulatory mechanisms involved in the decline of the lactase activity.
FEBS Lett
329
106-10
1993
Oryctolagus cuniculus
Saarela, T; Similä, S; Koivisto, M
Hypercalcemia and nephrocalcinosis in patients with congenital lactase deficiency.
J Pediatr
127
920-3
1995
Homo sapiens
Boukamel, R; Neuville, P; Duluc, I; Freund, JN
Activity of the rat lactase gene promoter in transfected human colon cancer cells.
C R Acad Sci III
318
1133-40
1995
Homo sapiens, Rattus, Felis catus
Aragón, JJ; Cañada, FJ; Fernández-Mayoralas, A; López, R; MartÃn-Lomas, M; Villanueva, D
A direct enzymatic synthesis of beta-D-galactopyranosyl-D-xylopyranosides and their use to evaluate rat intestinal lactase activity in vivo.
Carbohydr Res
290
209-16
1996
Rattus, Ovis aries, Metazoa
Sakuma, K; Watanabe, Y; Kurahashi, Y
Dietary control of lactase expression in the weaning rat.
Biomed Environ Sci
9
181-4
1996
Rattus
Vesa, TH; Marteau, P; Zidi, S; Briet, F; Pochart, P; Rambaud, JC
Digestion and tolerance of lactose from yoghurt and different semi-solid fermented dairy products containing Lactobacillus acidophilus and bifidobacteria in lactose maldigesters--is bacterial lactase important?
Eur J Clin Nutr
50
730-3
1996
Lactobacillus acidophilus, Lactobacillus delbrueckii subsp. bulgaricus, Bifidobacterium sp.
Acevedo, F; Gentina, JC; Bojorge, N; Reyes, I; Torres, A
Development of a pilot-plant fermentation process for the production of yeast lactase.
Ann N Y Acad Sci
799
559-62
1996
Saccharomyces cerevisiae
Harvey, CB; Wang, Y; Darmoul, D; Phillips, A; Mantei, N; Swallow, DM
Characterisation of a human homologue of a yeast cell division cycle gene, MCM6, located adjacent to the 5' end of the lactase gene on chromosome 2q21.
FEBS Lett
398
135-40
1996
Saccharomyces cerevisiae, Homo sapiens, Rattus
Dudley, MA; Burrin, DG; Quaroni, A; Rosenberger, J; Cook, G; Nichols, BL; Reeds, PJ
Lactase phlorhizin hydrolase turnover in vivo in water-fed and colostrum-fed newborn pigs.
Biochem J
320 ( Pt 3)
735-43
1996
Suidae
Nichols, BL; Dudley, MA; Nichols, VN; Putman, M; Avery, SE; Fraley, JK; Quaroni, A; Shiner, M; Carrazza, FR
Effects of malnutrition on expression and activity of lactase in children.
Gastroenterology
112
742-51
1997
Homo sapiens
Vega Franco, L
[Secondary lactase deficiency in children and its epidemiologic implications]
Rev Invest Clin
48 Suppl
33-43
1996
Homo sapiens
Rossi, M; Maiuri, L; Fusco, MI; Salvati, VM; Fuccio, A; Auricchio, S; Mantei, N; Zecca, L; Gloor, SM; Semenza, G
Lactase persistence versus decline in human adults: multifactorial events are involved in down-regulation after weaning.
Gastroenterology
112
1506-14
1997
Homo sapiens, Mammalia
Motohashi, Y; Fukushima, A; Kondo, T; Sakuma, K
Lactase decline in weaning rats is regulated at the transcriptional level and not caused by termination of milk ingestion.
J Nutr
127
1737-43
1997
Rattus
Jost, B; Duluc, I; Richardson, M; Lathe, R; Freund, JN
Functional diversity and interactions between the repeat domains of rat intestinal lactase.
Biochem J
327 ( Pt 1)
95-103
1997
Rattus
Peuhkuri, K; Hukkanen, M; Beale, R; Polak, JM; Vapaatalo, H; Korpela, R
Age and continuous lactose challenge modify lactase protein expression and enzyme activity in gut epithelium in the rat.
J Physiol Pharmacol
48
719-29
1997
Rattus
Lee, MF; Krasinski, SD
Human adult-onset lactase decline: an update.
Nutr Rev
56
1-8
1998
Homo sapiens
Fitzgerald, K; Bazar, L; Avigan, MI
GATA-6 stimulates a cell line-specific activation element in the human lactase promoter.
Am J Physiol
274
G314-24
1998
Homo sapiens
Tanaka, T; Kishi, K; Igawa, M; Takase, S; Goda, T
Dietary carbohydrates enhance lactase/phlorizin hydrolase gene expression at a transcription level in rat jejunum.
Biochem J
331 ( Pt 1)
225-30
1998
Rattus, Lateolabrax japonicus
Wang, Y; Harvey, CB; Hollox, EJ; Phillips, AD; Poulter, M; Clay, P; Walker-Smith, JA; Swallow, DM
The genetically programmed down-regulation of lactase in children.
Gastroenterology
114
1230-6
1998
Homo sapiens, collection
Shulman, RJ; Schanler, RJ; Lau, C; Heitkemper, M; Ou, CN; Smith, EO
Early feeding, feeding tolerance, and lactase activity in preterm infants.
J Pediatr
133
645-9
1998
Homo sapiens
Jost, B; Duluc, I; Vilotte, JL; Freund, JN
Lactase is unchanged in suckling mice fed with lactose-free milk.
Gastroenterol Clin Biol
22
863-7
1998
Mus sp., Metazoa, Mammalia
Koetse, HA; Stellaard, F; Bijleveld, CM; Elzinga, H; Boverhof, R; van der Meer, R; Vonk, RJ; Sauer, PJ
Non-invasive detection of low-intestinal lactase activity in children by use of a combined 13CO2/H2 breath test.
Scand J Gastroenterol
34
35-40
1999
Homo sapiens
Jost, B; Vilotte, JL; Duluc, I; Rodeau, JL; Freund, JN
Production of low-lactose milk by ectopic expression of intestinal lactase in the mouse mammary gland.
Nat Biotechnol
17
160-4
1999
Mus musculus, Metazoa, Mus sp.
Bernstein, JA; Bernstein, DI; Stauder, T; Lummus, Z; Bernstein, IL
A cross-sectional survey of sensitization to Aspergillus oryzae-derived lactase in pharmaceutical workers.
J Allergy Clin Immunol
103
1153-7
1999
Aspergillus, Aspergillus oryzae, Homo sapiens, Areas
Srinivasan, U; Jones, E; Weir, DG; Feighery, C
Lactase enzyme, detected immunohistochemically, is lost in active celiac disease, but unaffected by oats challenge.
Am J Gastroenterol
94
2936-41
1999
Avena sativa, Homo sapiens, Hordeum vulgare, Secale cereale, Triticum aestivum
Hollox, EJ; Poulter, M; Wang, Y; Krause, A; Swallow, DM
Common polymorphism in a highly variable region upstream of the human lactase gene affects DNA-protein interactions.
Eur J Hum Genet
7
791-800
0
Homo sapiens, Primates, Suidae, Sus scrofa, Mammalia
Coenen, TM; Bertens, AM; de Hoog, SC; Verspeek-Rip, CM
Safety evaluation of a lactase enzyme preparation derived from Kluyveromyces lactis.
Food Chem Toxicol
38
671-7
2000
Kluyveromyces lactis
Dudley, MA; Schoknecht, PA; Dudley, AW; Jiang, L; Ferraris, RP; Rosenberger, JN; Henry, JF; Reeds, PJ
Lactase synthesis is pretranslationally regulated in protein-deficient pigs fed a protein-sufficient diet.
Am J Physiol Gastrointest Liver Physiol
280
G621-8
2001
Suidae, Metazoa
Boey, CC
Lactase deficiency among Malaysian children with recurrent abdominal pain.
J Paediatr Child Health
37
157-60
2001
Homo sapiens, Malaya
Yang, Y; He, M; Cui, H; Bian, L; Wang, Z
The prevalence of lactase deficiency and lactose intolerance in Chinese children of different ages.
Chin Med J (Engl)
113
1129-32
2000
Homo sapiens, Bos taurus
Lee, SY; Wang, Z; Lin, CK; Contag, CH; Olds, LC; Cooper, AD; Sibley, E
Regulation of intestine-specific spatiotemporal expression by the rat lactase promoter.
J Biol Chem
277
13099-105
2002
Rattus, Mus musculus, Mus sp.
Kanabar, D; Randhawa, M; Clayton, P
Improvement of symptoms in infant colic following reduction of lactose load with lactase.
J Hum Nutr Diet
14
359-63
2001
Homo sapiens
Pfefferkorn, MD; Fitzgerald, JF; Croffie, JM; Gupta, SK; Corkins, MR; Molleston, JP
Lactase deficiency: not more common in pediatric patients with inflammatory bowel disease than in patients with chronic abdominal pain.
J Pediatr Gastroenterol Nutr
35
339-43
2002
Homo sapiens
Zhang, W; Yao, B; Wang, L; Fan, YL
[Cloning and sequencing of lactase gene from Aspergillus candidus]
Sheng Wu Gong Cheng Xue Bao
18
566-71
2002
Aspergillus candidus, Aspergillus oryzae, other sequences
Labayen, I; MartÃnez, JA
[Probiotic bacteria and lactase deficiencies]
Gastroenterol Hepatol
26 Suppl 1
64-72
2003
Bacteria
Vodilova, OV; Gapparov, MM; Nikol'skaia, GV
[Lactase deficiency in children of the first year of life]
Vopr Pitan
72
10-3
2003
Homo sapiens
LANDMAN, OE; BONNER, DM
Neurospora lactase. I. Properties of lactase preparations from a lactose utilizing and a lactose non-utilizing strain.
Arch Biochem Biophys
41
253-65
1952
Neurospora
YANOFSKY, C
Effects of x-rays on the formation of lactase in a lysogenic strain and a sensitive strain of Escherichia coli.
J Bacteriol
65
383-7
1953
Escherichia coli
LANDMAN, OE
Neurospora lactase. II. Enzyme formation in the standard strain.
Arch Biochem
52
93-109
1954
Neurospora
DAVIES, A
Some factors affecting lactase formation and activity in Saccharomyces fragilis.
J Gen Microbiol
14
425-39
1956
Saccharomyces
NOVIKOVA, SI
[Studies on lactase activity of Streptococcus lactis.]
Mikrobiol Zh
18
40-4
1956
Lactococcus lactis
NOVYKOVA, SI
[Examination of activity lactase of Streptococcus lactis. II.]
Mikrobiol Zh
19
29-33
1957
Lactococcus lactis
GIRARDET, P; RICHTERICH, R; ANTENER, I
[ADAPTATION OF THE INTESTINAL LACTASE TO THE ADMINISTRATION OF LACTOSE IN THE ADULT RAT.]
Helv Physiol Pharmacol Acta
22
7-14
1964
Rattus
Beja-Pereira, A; Luikart, G; England, PR; Bradley, DG; Jann, OC; Bertorelle, G; Chamberlain, AT; Nunes, TP; Metodiev, S; Ferrand, N; Erhardt, G
Gene-culture coevolution between cattle milk protein genes and human lactase genes.
Nat Genet
35
311-3
2003
Homo sapiens, Bos taurus
HEILSKOV, NS
Studies on animal lactase. II. Distribution in some of the glands of the digestive tract.
Acta Physiol Scand
24
84-9
1951
animal
HEILSKOV, NS
Studies on animal lactase. I. Lactase activity determination.
Acta Physiol Scand
22
267-76
1951
animal
Mateo, C; Monti, R; Pessela, BC; Fuentes, M; Torres, R; Guisán, JM; Fernández-Lafuente, R
Immobilization of lactase from Kluyveromyces lactis greatly reduces the inhibition promoted by glucose. full hydrolysis of lactose in milk.
Biotechnol Prog
20
1259-62
0
Kluyveromyces lactis
Ontsouka, EC; Korczak, B; Hammon, HM; Blum, JW
Real-time PCR quantification of bovine lactase mRNA: localization in the gastrointestinal tract of milk-fed calves.
J Dairy Sci
87
4230-7
2004
Bos taurus, Homo sapiens, Oryctolagus cuniculus, Rattus, Metazoa, Lamina
Roy, P; Aubert-Jacquin, C; Avart, C; Gontier, C
[Benefits of a thickened infant formula with lactase activity in the management of benign digestive disorders in newborns]
Arch Pediatr
11
1546-54
2004
Homo sapiens
Shulman, RJ; Wong, WW; Smith, EO
Influence of changes in lactase activity and small-intestinal mucosal growth on lactose digestion and absorption in preterm infants.
Am J Clin Nutr
81
472-9
2005
Homo sapiens
Tan-Dy, CR; Ohlsson, A
Lactase treated feeds to promote growth and feeding tolerance in preterm infants.
Cochrane Database Syst Rev
CD004591
2005
Homo sapiens, collection
Kaur, J; Kaur, K; Mahmood, A; Mahmood, S
In vitro translation of RNA to lactase during postnatal development of rat intestine.
J Biosci
30
183-9
2005
Rattus, Metazoa
Coelho, M; Luiselli, D; Bertorelle, G; Lopes, AI; Seixas, S; Destro-Bisol, G; Rocha, J
Microsatellite variation and evolution of human lactase persistence.
Hum Genet
117
329-39
2005
Homo sapiens
Zhang, W; Fan, YL; Yao, B
[Overexpression of Aspergillus candidus lactase and analysis of enzymatic properties]
Wei Sheng Wu Xue Bao
45
247-52
2005
Aspergillus candidus, Aspergillus oryzae, Komagataella pastoris
He, W; Lü, B; Huang, C
[Lactase and its gene regulation in BALB/c mice at different ages]
Sichuan Da Xue Xue Bao Yi Xue Ban
36
516-8
2005
Mus sp., Homo sapiens
O'leary, VS; Woychik, JH
Utilization of Lactose, Glucose, and Galactose by a Mixed Culture of Streptococcus thermophilus and Lactobacillus bulgaricus in Milk Treated with Lactase Enzyme.
Appl Environ Microbiol
32
89-94
1976
Streptococcus thermophilus, Lactobacillus delbrueckii subsp. bulgaricus, mixed culture
de Bales, SA; Castillo, FJ
Production of Lactase by Candida pseudotropicalis Grown in Whey.
Appl Environ Microbiol
37
1201-1205
1979
Kluyveromyces marxianus
Koetse, HA; Vonk, RJ; Gonera-De Jong, GB; Priebe, MG; Antoine, JM; Stellaard, F; Sauer, PJ
Low lactase activity in a small-bowel biopsy specimen: Should dietary lactose intake be restricted in children with small intestinal mucosal damage?
Scand J Gastroenterol
41
37-41
2006
Homo sapiens
Hershey, AD; Bronfenbrenner, J
Dissociation and Lactase Activity in Slow Lactose-Fermenting Bacteria of Intestinal Origin.
J Bacteriol
31
453-464
1936
Bacteria
Deere, CJ; Dulaney, AD; Michelson, ID
The Lactase Activity of Escherichia coli-mutabile.
J Bacteriol
37
355-363
1939
Escherichia
Deere, CJ
On the "Activation" of the Lactase of Escherichia coli-mutabile.
J Bacteriol
37
473-483
1939
Escherichia
Wang, Z; Maravelias, C; Sibley, E
Lactase gene promoter fragments mediate differential spatial and temporal expression patterns in transgenic mice.
DNA Cell Biol
25
215-22
2006
Mus musculus, Rattus
Burrin, DG; Dudley, MA; Reeds, PJ; Shulman, RJ; Perkinson, S; Rosenberger, J
Feeding colostrum rapidly alters enzymatic activity and the relative isoform abundance of jejunal lactase in neonatal pigs.
J Nutr
124
2350-7
1994
Suidae
Kaur, K; Mahmood, S; Mahmood, A
Susceptibility of lactase to luminal proteases in developing rat intestine.
Indian J Gastroenterol
25
179-81
0
Rattus, Metazoa, Homo sapiens
Plimmer, RH
On the presence of lactase in the intestines of animals and on the adaptation of the intestine to lactose.
J Physiol
35
20-31
1906
Metazoa
He, W; Lü, B; Huang, CY
[Study on the distribution of lactase in the small intestine of SD rats]
Sichuan Da Xue Xue Bao Yi Xue Ban
37
785-6, 800
2006
Rattus
Tishkoff, SA; Reed, FA; Ranciaro, A; Voight, BF; Babbitt, CC; Silverman, JS; Powell, K; Mortensen, HM; Hirbo, JB; Osman, M; Ibrahim, M; Omar, SA; Lema, G; Nyambo, TB; Ghori, J; Bumpstead, S; Pritchard, JK; Wray, GA; Deloukas, P
Convergent adaptation of human lactase persistence in Africa and Europe.
Nat Genet
39
31-40
2007
Homo sapiens
Abdel-Hafez, MA; El-Hawey, AM; Waheeb, AA; Hussein, AT; Soliman, AA
Lactase deficiency in patients with intestinal schistosomiasis.
Ann Saudi Med
13
31-6
1993
Homo sapiens
Enattah, NS; Trudeau, A; Pimenoff, V; Maiuri, L; Auricchio, S; Greco, L; Rossi, M; Lentze, M; Seo, JK; Rahgozar, S; Khalil, I; Alifrangis, M; Natah, S; Groop, L; Shaat, N; Kozlov, A; Verschubskaya, G; Comas, D; Bulayeva, K; Mehdi, SQ; Terwilliger, JD; Sahi, T; Savilahti, E; Perola, M; Sajantila, A; Järvelä, I; Peltonen, L
Evidence of still-ongoing convergence evolution of the lactase persistence T-13910 alleles in humans.
Am J Hum Genet
81
615-25
2007
Homo sapiens
Friend, BA; Shahani, KM
Characterization and evaluation of Aspergillus oryzae lactase coupled to a regenerable support.
Biotechnol Bioeng
24
329-45
1982
Aspergillus oryzae, Aspergillus
Jarvela, I; Torniainen, S; Kolho, KL
Molecular genetics of human lactase deficiencies.
Ann Med
1-8
2009
Homo sapiens
Almon, R; Alvarez-Leon, EE; Engfeldt, P; Serra-Majem, L; Magnuson, A; Nilsson, TK
Associations between lactase persistence and the metabolic syndrome in a cross-sectional study in the Canary Islands.
Eur J Nutr
2009
Serinus canaria, Homo sapiens
Knopfmacher, HP; Salle, AJ
STUDIES ON THE LACTASE OF ESCHERICHIA COLI.
J Gen Physiol
24
377-397
1941
Escherichia coli
Truedsson, M; Carlson, J; Simrén, M; Ohlsson, B
Polymorphism in the oxytocin promoter region in patients with lactase non-persistence is not related to symptoms.
BMC Gastroenterol
9
90
2009
Homo sapiens
Almon, R; Patterson, E; Nilsson, TK; Engfeldt, P; Sjöström, M
Body fat and dairy product intake in lactase persistent and non-persistent children and adolescents.
Food Nutr Res
54
2010
Homo sapiens
Gerbault, P; Liebert, A; Itan, Y; Powell, A; Currat, M; Burger, J; Swallow, DM; Thomas, MG
Evolution of lactase persistence: an example of human niche construction.
Philos Trans R Soc Lond B Biol Sci
366
863-77
2011
Homo sapiens, Mammalia, animal
Weinlander, KM; Hall, DJ; De Stasio, EA
RFLP analysis and allelic discrimination with real-time PCR using the human lactase persistence trait: A pair of molecular genetic investigations.
Biochem Mol Biol Educ
38
167-71
2010
Homo sapiens
Romero, IG; Basu Mallick, C; Liebert, A; Crivellaro, F; Chaubey, G; Itan, Y; Metspalu, M; Eaaswarkhanth, M; Pitchappan, R; Villems, R; Reich, D; Singh, L; Thangaraj, K; Thomas, MG; Swallow, DM; Lahr, MM; Kivisild, T
Herders of Indian and European cattle share their predominant allele for lactase persistence.
Mol Biol Evol
2011
Bos taurus, Homo sapiens, Arabia
Rao, P; Rao, N; Jordinson, M; Scott, C; Hinchcliffe, C; Campbell, D
Comparison of quick point of care test for small bowel hypolactasia with biochemical lactase assay in children.
J Pediatr Gastroenterol Nutr
2011
Homo sapiens
Almon, R; Nilsson, TK; Sjöström, M; Engfeldt, P
Lactase persistence and milk consumption are associated with body height in Swedish preadolescents and adolescents.
Food Nutr Res
55
2011
Homo sapiens
Fang, L; Ahn, JK; Wodziak, D; Sibley, E
The human lactase persistence-associated SNP -13910*T enables in vivo functional persistence of lactase promoter-reporter transgene expression.
Hum Genet
2012
Homo sapiens, Mus musculus, Rattus, Mammalia
Furnari, M; Bonfanti, D; Parodi, A; Franzè, J; Savarino, E; Bruzzone, L; Moscatelli, A; Di Mario, F; Dulbecco, P; Savarino, V
A Comparison Between Lactose Breath Test and Quick Test on Duodenal Biopsies for Diagnosing Lactase Deficiency in Patients With Self-reported Lactose Intolerance.
J Clin Gastroenterol
2012
Homo sapiens
Uchida, N; Sakamoto, O; Irie, M; Abukawa, D; Takeyama, J; Kure, S; Tsuchiya, S
Two novel mutations in the lactase gene in a Japanese infant with congenital lactase deficiency.
Tohoku J Exp Med
227
69-72
2012
Homo sapiens
Elguezabal, N; Chamorro, S; Molina, E; Garrido, JM; Izeta, A; Rodrigo, L; Juste, RA
Lactase persistence, NOD2 status and Mycobacterium avium subsp. paratuberculosis infection associations to Inflammatory Bowel Disease.
Gut Pathog
4
6
2012
Mycobacterium avium subsp. paratuberculosis
Kuchay, RA; Anwar, M; Thapa, BR; Mahmood, A; Mahmood, S
Correlation of G/A -22018 single-nucleotide polymorphism with lactase activity and its usefulness in improving the diagnosis of adult-type hypolactasia among North Indian children.
Genes Nutr
2012
Homo sapiens
Almon, R; Alvarez-León, EE; Serra-Majem, L
Association of the European Lactase Persistence Variant (LCT-13910 C>T Polymorphism) with Obesity in the Canary Islands.
PLoS One
7
e43978
2012
Serinus canaria
Demir, M; Turhan, I; Kucukcetin, A; Alpkent, Z
Oil production by Mortierella isabellina from whey treated with lactase.
Bioresour Technol
128
365-9
2013
Umbelopsis isabellina
Albuquerque, D; Nóbrega, C; Manco, L
The lactase persistence -13910C>T polymorphism shows indication of association with abdominal obesity among Portuguese children.
Acta Paediatr
2012
Homo sapiens
Al-Abri, AR; Al-Rawas, O; Al-Yahyaee, S; Al-Habori, M; Al-Zubairi, AS; Bayoumi, R
Distribution of the lactase persistence-associated variant alleles -13910* T and -13915* G among the people of Oman and Yemen.
Hum Biol
84
271-86
2012
Homo sapiens, Arabia, Colotis
Kienast, W; Haeseler, K; Herterich, R
Protein-losing enteropathy following the Fontan procedure in a child with intestinal lactase deficiency treated with lactose-free diet.
Cardiol Young
1-3
2013
Homo sapiens
Malek, AJ; Klimentidis, YC; Kell, KP; Fernández, JR
Associations of the lactase persistence allele and lactose intake with body composition among multiethnic children.
Genes Nutr
2013
Homo sapiens
Tan-Dy, CR; Ohlsson, A
Lactase treated feeds to promote growth and feeding tolerance in preterm infants.
Cochrane Database Syst Rev
3
CD004591
2013
Homo sapiens
Hermida, C; Martínez-Costa, OH; Corrales, G; Teruel, C; Sánchez, V; Sánchez, JJ; Sarrión, D; Ariza, MJ; Codoceo, R; Calvo, I; Fernández-Mayoralas, A; Aragón, JJ
Improvement and Validation of d-Xylose Determination in Urine and Serum as a New Tool for the Noninvasive Evaluation of Lactase Activity in Humans.
J Clin Lab Anal
2014
Homo sapiens
Du, HT; Zhu, HY; Wang, JM; Zhao, W; Tao, XL; Ba, CF; Tian, YM; Su, YH
Single-nucleotide polymorphisms and activity analysis of the promoter and enhancer of the pig lactase gene.
Gene
545
56-60
2014
Sus scrofa, Homo sapiens, Suidae
Ibba, I; Gilli, A; Boi, MF; Usai, P
Effects of exogenous lactase administration on hydrogen breath excretion and intestinal symptoms in patients presenting lactose malabsorption and intolerance.
Biomed Res Int
2014
680196
2014
Homo sapiens
Szilagyi, A; Leighton, H; Burstein, B; Xue, X
Latitude, sunshine, and human lactase phenotype distributions may contribute to geographic patterns of modern disease: the inflammatory bowel disease model.
Clin Epidemiol
6
183-98
2014
Homo sapiens
de Vrese, M; Laue, C; Offick, B; Soeth, E; Repenning, F; Thoß, A; Schrezenmeir, J
A combination of acid lactase from Aspergillus oryzae and yogurt bacteria improves lactose digestion in lactose maldigesters synergistically: A randomized, controlled, double-blind cross-over trial.
Clin Nutr
2014
Bacteria, Aspergillus oryzae
Almon, R; Sjöström, M; Nilsson, TK
Lactase non-persistence as a determinant of milk avoidance and calcium intake in children and adolescents.
J Nutr Sci
2
e26
2013
Homo sapiens
Priehodová, E; Abdelsawy, A; Heyer, E; Cerný, V
Lactase persistence variants in Arabia and in the African Arabs.
Hum Biol
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Colotis, Arabia, Homo sapiens, animal
Kuchay, RA; Thapa, BR; Mahmood, A; Anwar, M; Mahmood, S
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Ann Hum Biol
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Homo sapiens
Baffour-Awuah, NY; Fleet, S; Montgomery, RK; Baker, SS; Butler, JL; Campbell, C; Tischfield, S; Mitchell, PD; Allende-Richter, S; Moon, JE; Fishman, L; Bousvaros, A; Fox, V; Kuokkanen, M; Grand, RJ; Hirschhorn, JN
Functional Significance of Single Nucleotide Polymorphisms in the Lactase Gene in Diverse US Patients and Evidence for a Novel Lactase Persistence Allele at -13909 in Those of European Ancestry.
J Pediatr Gastroenterol Nutr
60
182-91
2015
Homo sapiens
Magiera, R; Schürer-Maly, CC; Mortsiefer, A; Abholz, HH; Maly, FE; Pentzek, M
Are there differences between patients with and without the homozygous--13910CC genetic variant in the MCM-6 gene upstream from the lactase gene?--A non-randomised, two armed intervention study without control group.
Clin Lab
60
1617-25
2014
Homo sapiens
Paar, C; Enko, D; Zahel, B; Mayr, R; Berg, J
Reliable analysis of the single nucleotide polymorphism of lactase persistence LPH(-13910) C/T from saliva derived DNA: validation of a standardized saliva collection system.
Clin Lab
60
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collection, Homo sapiens
Marushko, YV; Iovitsa, TV
[THERAPY OF TRANSIENT LACTASE INSUFFICIENCY OF CHILDREN IN PECTORAL AGE].
Lik Sprava
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Homo sapiens
van de Heijning, BJ; Kegler, D; Schipper, L; Voogd, E; Oosting, A; van der Beek, EM
Acute and Chronic Effects of Dietary Lactose in Adult Rats Are not Explained by Residual Intestinal Lactase Activity.
Nutrients
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2015
Rattus, Metazoa
Szilagyi, A
Adaptation to Lactose in Lactase Non Persistent People: Effects on Intolerance and the Relationship between Dairy Food Consumption and Evalution of Diseases.
Nutrients
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Homo sapiens
Pinto, JC; Oliveira, S; Teixeira, S; Martins, D; Fehn, AM; Aço, T; Gayà-Vidal, M; Rocha, J
Food and pathogen adaptations in the Angolan Namib desert: Tracing the spread of lactase persistence and human African trypanosomiasis resistance into southwestern Africa.
Am J Phys Anthropol
2016
Homo sapiens
Bayoumi, R; De Fanti, S; Sazzini, M; Giuliani, C; Quagliariello, A; Bortolini, E; Boattini, A; Al-Habori, M; Al-Zubairi, AS; Rose, JI; Romeo, G; Al-Abri, A; Luiselli, D
Positive selection of lactase persistence among people of Southern Arabia.
Am J Phys Anthropol
2016
Homo sapiens, Arabia
Francesconi, CF; Machado, MB; Steinwurz, F; Nones, RB; Quilici, FA; Catapani, WR; Miszputen, SJ; Bafutto, M
ORAL ADMINISTRATION OF EXOGENOUS LACTASE IN TABLETS FOR PATIENTS DIAGNOSED WITH LACTOSE INTOLERANCE DUE TO PRIMARY HYPOLACTASIA.
Arq Gastroenterol
53
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0
Homo sapiens
Howell, JN; Schockenhoff, T; Flatz, G
Population screening for the human adult lactase phenotypes with a multiple breaths version of the breath hydrogen test.
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On the Evolution of Lactase Persistence in Humans.
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Homo sapiens
Venkateswarulu, TC; Prabhakar, KV; Kumar, RB; Krupanidhi, S
Modeling and optimization of fermentation variables for enhanced production of lactase by isolated Bacillus subtilis strain VUVD001 using artificial neural networking and response surface methodology.
3 Biotech
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Bacillus subtilis
Geoghegan, AR; Webb, D
Successful Treatment With Phenobarbital Following Lactase Supplementation in an Infant With Lactose Intolerance.
Ann Pharmacother
51
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Homo sapiens
Hajare, ST; Bekele, G
Effect of Probiotic strain Lactobacillus acidophilus (LBKV-3) on fecal residual lactase activity in undernourished children below 10 year.
J Immunoassay Immunochem
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Lactobacillus acidophilus, Homo sapiens
Long, CX; He, L; Guo, YF; Liu, YW; Xiao, NQ; Tan, ZJ
Diversity of bacterial lactase genes in intestinal contents of mice with antibiotics-induced diarrhea.
World J Gastroenterol
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7584-7593
2017
Mus sp.
He, L; Liu, Y; Guo, Y; Shen, K; Hui, H; Tan, Z
Diversity of intestinal bacterial lactase gene in antibiotics-induced diarrhea mice treated with Chinese herbs compound Qi Wei Bai Zhu San.
3 Biotech
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2018
Mus sp.
Antelope, CX; Marnetto, D; Casey, F; Huerta-Sanchez, E
Leveraging Multiple Populations across Time Helps Define Accurate Models of Human Evolution: A Reanalysis of the Lactase Persistence Adaptation.
Hum Biol
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2017
Homo sapiens
Long, C; Liu, Y; He, L; Tan, Q; Yu, Z; Xiao, N; Tan, Z
Bacterial lactase genes diversity in intestinal mucosa of mice with dysbacterial diarrhea induced by antibiotics.
3 Biotech
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176
2018
Mus sp.
Sorthe, J; Moghaddam, A
Lactase persistence may explain the paradoxical findings of high vitamin D concentrations in Europeans living in areas of low UV-B irradiation.
Eur J Clin Nutr
2018
Areas
Almazar, AE; Chang, JY; Larson, JJ; Atkinson, EJ; Locke, GR; Talley, NJ; Saito, YA
Comparison of Lactase Variant MCM6 -13910 C>T Testing and Self-report of Dairy Sensitivity in Patients With Irritable Bowel Syndrome.
J Clin Gastroenterol
2018
Homo sapiens
Montalva, N; Adhikari, K; Liebert, A; Mendoza-Revilla, J; Flores, SV; Mace, R; Swallow, DM
Adaptation to milking agropastoralism in Chilean goat herders and nutritional benefit of lactase persistence.
Ann Hum Genet
2018
Capra hircus, Homo sapiens
Long, C; Liu, Y; He, L; Yu, R; Li, D; Tan, Z; Hui, H
Bacterial lactase genes diversity in intestinal mucosa of dysbacterial diarrhea mice treated with Qiweibaizhu powder.
3 Biotech
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423
2018
Mus sp., metagenome
Kato, K; Ishida, S; Tanaka, M; Mitsuyama, E; Xiao, JZ; Odamaki, T
Association between functional lactase variants and a high abundance of Bifidobacterium in the gut of healthy Japanese people.
PLoS One
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2018
Bifidobacterium, Homo sapiens, Microbiota
Ahmed, M; Billoo, AG; Iqbal, K; Memon, A
Clinical Efficacy Of Lactase Enzyme Supplement In Infant Colic: A Randomised Controlled Trial.
J Pak Med Assoc
68
1744-1747
2018
Homo sapiens
Treister-Goltzman, Y; Peleg, R
Primary lactase deficiency and bone mineral density in postmenopausal women.
Osteoporos Int
2019
Homo sapiens
Vionnet, N; Münger, LH; Freiburghaus, C; Burton, KJ; Pimentel, G; Pralong, FP; Badertscher, R; Vergères, G
Assessment of lactase activity in humans by measurement of galactitol and galactonate in serum and urine after milk intake.
Am J Clin Nutr
109
470-477
2019
Homo sapiens
Zuccherato, LW; Elói-Santos, SM; Jardim, LL; Camelo, RM; Chaves, DG; Souza, RP; Hollox, EJ; Rezende, SM
Variation of rs3754689 at lactase gene and inhibitors in admixed Brazilian patients with hemophilia A.
Haematologica
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Homo sapiens
Hussein, L; Elsayed, S; Foda, S
Reduction of Lactose in Milk by Purified Lactase Produced by Kluyveromyces lactis.
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Selective lactase deficiency is common in pediatric patients undergoing upper endoscopy.
J Mol Biochem
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2018
Homo sapiens
Forsgård, RA
Lactose digestion in humans: intestinal lactase appears to be constitutive whereas the colonic microbiome is adaptable.
Am J Clin Nutr
110
273-279
2019
Homo sapiens, Indicator
He, Y; Tang, Y; Peng, M; Xie, G; Li, W; Tan, Z
Influence of Debaryomyces hansenii on bacterial lactase gene diversity in intestinal mucosa of mice with antibiotic-associated diarrhea.
PLoS One
14
e0225802
2019
Debaryomyces hansenii, Mus sp., Lysobacter, Pseudomonas, Citrobacter, Enterobacter, Proteobacteria, Firmicutes, Acidovorax, Stenotrophomonas, Cupriavidus, Actinobacteria
Wu, Y; Tang, Y; Xiao, NQ; Wang, CH; Tan, ZJ
Bacterial Lactase Gene Characteristics in Intestinal Contents of Antibiotic-Associated Diarrhea Mice Treated with Debaryomyces hansenii.
Med Sci Monit
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Debaryomyces hansenii, Mus sp., Bacteria, Enterobacter, Modestobacter, Fretibacterium
Abaturov, A; Nikulina, A
Genotype C/C 13910 of the Lactase Gene as a Risk Factor for the Formation of Insulin-Resistant Obesity in Children.
Acta Medica (Hradec Kralove)
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150-155
2019
Homo sapiens
Singh, M; Singh, V; Friesen, CA
Colonic mucosal inflammatory cells in children and adolescents with lactase deficiency.
Pathol Res Pract
216
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Homo sapiens
Wang, Q; Lillevang, SK; Rydtoft, SM; Xiao, H; Fan, MT; Solem, C; Liu, JM; Jensen, PR
No more cleaning up - Efficient lactic acid bacteria cell catalysts as a cost-efficient alternative to purified lactase enzymes.
Appl Microbiol Biotechnol
104
6315-6323
2020
Bacteria, Streptococcus thermophilus, bacterium, Lactococcus lactis
Wellenbeck, W; Mampel, J; Naumer, C; Knepper, A; Neubauer, P
Fast-track development of a lactase production process with Kluyveromyces lactis by a progressive parameter-control workflow.
Eng Life Sci
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2017
Kluyveromyces lactis
Mank, E; van Harskamp, D; van Toledo, L; van Goudoever, JB; Schierbeek, H
Simultaneous assessment of intestinal permeability and lactase activity in human-milk-fed preterm infants by sugar absorption test: Clinical implementation and analytical method.
Clin Nutr
2020
Homo sapiens
Schmidt, V; Enav, H; Spector, TD; Youngblut, ND; Ley, RE
Strain-Level Analysis of Bifidobacterium spp. from Gut Microbiomes of Adults with Differing Lactase Persistence Genotypes.
mSystems
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2020
Bifidobacterium, gut metagenome, Homo sapiens, metagenomes
Wasuwanich, P; Choudry, H; Ingviya, T; Scheimann, AO; AuYeung, KJ; Karwowski, C; Billet, S; Nichols, BL; Karnsakul, W
A retrospective study on the association of gastrointestinal symptoms in children with low lactase activity and low activity of other disaccharidases.
BMC Gastroenterol
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Homo sapiens
Saag, L
Human Genetics: Lactase Persistence in a Battlefield.
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Homo sapiens
Panagopoulos, V; Dima, A; Boura, K; Bosnea, L; Nigam, PS; Kanellaki, M; Koutinas, AA
Cell factory models of non-engineered S. cerevisiae containing lactase in a second layer for lactose fermentation in one batch.
Enzyme Microb Technol
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Saccharomyces cerevisiae, Lacticaseibacillus casei
Campbell, MC; Ranciaro, A
Human adaptation, demography and cattle domestication: an overview of the complexity of lactase persistence in Africa.
Hum Mol Genet
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2021
Homo sapiens, Bos taurus, animal
Wang, L; Wang, YW; Tan, JT; Yan, J; Wu, Y; Wang, XM; Yang, WZ; Qian, JH
[Efficacy and safety of lactase additive in preterm infants with lactose intolerance: a prospective randomized controlled trial].
Zhongguo Dang Dai Er Ke Za Zhi
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Homo sapiens, Enterococcus, Lactobacillus, Bifidobacterium
Liu, YH; Wang, L; Zhang, Z; Otecko, NO; Khederzadeh, S; Dai, Y; Liang, B; Wang, GD; Zhang, YP
Whole-genome sequencing reveals lactase persistence adaptation in European dogs.
Mol Biol Evol
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Canis lupus familiaris
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Late-onset hypolactasia and persistent high lactase activity in humans.
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The Biochemical journal
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Ligation or external fistulation of the common bile duct in the rat. II. Intestinal disaccharidase activities.
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Rattus, Metazoa
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[Effects of colchicine treatment on rat intestinal disaccharidase activities.]
Exp Pathol (Jena)
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Rattus
Antonowicz, I; Lebenthal, E; Schwachman, H
Disaccharidase activities in small intestinal mucosa in patients with cystic fibrosis.
J Pediatr
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Homo sapiens
Saito, M; Suda, M; Matzuda, H
Postnatal development of circadian rhythms in disaccharidase activities in rat small intestine.
Am J Physiol
234
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1978
Rattus
Torres-Pinedo, R
Intestinal exfoliated cells in infant diarrhoea: changes in cell renewal and disaccharidase activities.
Ciba Found Symp
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1976
Homo sapiens, Escherichia coli
Nashiro, K; Murakami, K; Mimura, G
Diurnal variation and increase of disaccharidase activity in diabetic rats.
J Nutr Sci Vitaminol (Tokyo)
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Rattus
Daniels, CW; Belosevic, M
Disaccharidase activity in the small intestine of susceptible and resistant mice after primary and challenge infections with Giardia muris.
Am J Trop Med Hyg
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Giardia muris, Metazoa, Mus sp.
Samulitis-dos Santos, BK; Goda, T; Koldovskỳ, O
Dietary-induced increases of disaccharidase activities in rat jejunum.
Br J Nutr
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Human intestinal disaccharidase activities: correlations with age, biopsy technique, and degree of villus atrophy.
J Pediatr Gastroenterol Nutr
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Homo sapiens
Shulman, RJ; Langston, C; Lifschitz, CH
Histologic findings are not correlated with disaccharidase activities in infants with protracted diarrhea.
J Pediatr Gastroenterol Nutr
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Homo sapiens, Transformation
Shulman, RJ; Burrin, DG
Total parenteral nutrition energy composition affects small intestinal disaccharidase activity in the newborn miniature pig.
JPEN J Parenter Enteral Nutr
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Sus scrofa, Homo sapiens
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Disaccharidase activities in small intestine of rotavirus-infected suckling mice: a histochemical study.
J Pediatr Gastroenterol Nutr
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Mus sp., Murine rotavirus, Metazoa
Tadesse, K
The effect on intestinal disaccharidase activity of feeding galactose to growing rats.
Exp Physiol
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Rattus
Collins, AJ; James, PS; Smith, MW
Sugar-dependent selective induction of mouse jejunal disaccharidase activities.
J Physiol
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Mus musculus
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Selective effects of graft-versus-host reaction on disaccharidase expression by mouse jejunal enterocytes.
Clin Sci (Lond)
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Mus sp.
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Small bowel disaccharidase activity in the rat as affected by intestinal resection and pectin feeding.
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'Normal' disaccharidase levels in children.
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Homo sapiens
Toncheva, E; Profirov, Y; Voynova, R
Disaccharidase activity in intestine epithelium microvilli membranes of lambs during the first month after birth.
Arch Tierernahr
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Ovis aries
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Sequential disaccharidase loss in rat intestinal blind loops: impact of malnutrition.
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Carreras, O; Bolufer, J; Murillo, ML
Disaccharidase activities after jejunoileal bypass in rat.
Rev Esp Fisiol
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Rattus, Metazoa
Schedl, HP; Al-Jurf, AS; Wilson, HD
Elevated intestinal disaccharidase activity in the streptozotocin-diabetic rat is independent of enteral feeding.
Diabetes
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Rattus
Thomsen, LL; Tasman-Jones, C; Maher, C
Effects of dietary fat and gel-forming substances on rat jejunal disaccharidase levels.
Digestion
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Rattus norvegicus
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Small intestine of artificially reared rat pups: effect of caloric intake and dietary composition on growth and disaccharidase activities.
J Nutr
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1983
Rattus
Raul, F; Galluser, M; Doffoel, M
Stimulation of disaccharidase activities in the jejunal brush border membrane of adult rat by total parenteral nutrition. Effects of thyroid hormones.
Digestion
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Rattus
Lanzkowsky, P; Karayalcin, G; Miller, F
Disaccharidase levels in iron deficient rats at birth and during the nursing and postweaning periods: response to iron treatment.
Pediatr Res
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Rattus, Metazoa
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Disaccharidase deficiencies in Mongolian gerbils (Meriones unguiculatus) protected against Giardia lamblia.
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Entamoeba histolytica, Gerbillinae, Giardia, Giardia intestinalis, Metazoa
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Mus sp.
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Dietary carbohydrate and fat independently modulate disaccharidase activities in rat jejunum.
J Nutr
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Rattus, Metazoa
Shimizu, K; Mushiake, S; Yoshimura, N; Harada, T; Okada, S
The effect of spermine on the disaccharidase activities in suckling rats of different age.
Cell Biol Int
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Rattus
Rodriguez-Castilla, J; López-Nuevo, M; Delgado, MJ; Murillo, ML; Carreras, O
Changes in the ileal disaccharidase activities in rats after long-term ethanol feeding.
Alcohol Alcohol
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Rattus, Metazoa
Michail, S; Mohammadpour, M; Park, JH; Vanderhoof, JA
Soy-polysaccharide-supplemented soy formula enhances mucosal disaccharidase levels following massive small intestinal resection in rats.
J Pediatr Gastroenterol Nutr
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Metazoa
Houle, VM; Schroeder, EA; Odle, J; Donovan, SM
Small intestinal disaccharidase activity and ileal villus height are increased in piglets consuming formula containing recombinant human insulin-like growth factor-I.
Pediatr Res
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1997
Metazoa
Steeb, CB; Lamb, J; Shoubridge, CA; Tivey, DR; Penttila, I; Read, LC
Systemically but not orogastrically delivered insulin-like growth factor (IGF)-I and long [Arg3]IGF-I stimulates intestinal disaccharidase activity in two age groups of suckling rats.
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Rattus
Murakami, I; Ikeda, T
Effects of diabetes and hyperglycemia on disaccharidase activities in the rat.
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Rattus
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Disaccharidase activities in children: normal values and comparison based on symptoms and histologic changes.
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Homo sapiens
Kolho, KL; Savilahti, E
Ethnic differences in intestinal disaccharidase values in children in Finland.
J Pediatr Gastroenterol Nutr
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Homo sapiens
Blomme, B; Gerlo, E; Hauser, B; Vandenplas, Y
Disaccharidase activities in Belgian children: reference intervals and comparison with non-Belgian Caucasian children.
Acta Paediatr
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Homo sapiens
Courtois, P; Sener, A; Scott, FW; Malaisse, WJ
Disaccharidase activity in the intestinal tract of Wistar-Furth, diabetes-resistant and diabetes-prone BioBreeding rats.
Br J Nutr
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Rattus, Metazoa, Homo sapiens
Shu, D; Simpson, HV; Xu, RJ; Mellor, DJ; Reynolds, GW; Marshall, RB
Impact of Yersinia enterocolitica enteritis on disaccharidase activity and small intestinal morphology in colostrum-deprived newborn piglets.
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Metazoa
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Br J Nutr
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Rattus
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Sodium/glucose cotransporter-1, sweet receptor and disaccharidase expression in the intestine of the domestic dog and cat: species of different dietary habit.
Am J Physiol Regul Integr Comp Physiol
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Canis lupus familiaris, Felis catus
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Intestinal disaccharidase activity in patients with autism: Effect of age, gender, and intestinal inflammation.
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Homo sapiens
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Tinospora cordifolia, a Novel Source of Extracellular Disaccharidases, Useful for Human Disaccharidase Deficiency Therapy.
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Homo sapiens
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Disaccharidase activity in children with inflammatory bowel disease.
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Disaccharidase Deficiencies in Children With Chronic Abdominal Pain.
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Homo sapiens
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Demographic and Clinical Correlates of Mucosal Disaccharidase Deficiencies in Children With Functional Dyspepsia.
J Pediatr Gastroenterol Nutr
66 Suppl 3
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Homo sapiens
Cohen, SA; Oloyede, H; Gold, BD; Mohammed, A; Elser, HE
Clinical Characteristics of Disaccharidase Deficiencies Among Children Undergoing Upper Endoscopy.
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Homo sapiens
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Relationships between disaccharidase deficiencies, duodenal inflammation and symptom profile in children with abdominal pain.
Sci Rep
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Homo sapiens
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Patients with functional bowel disorder have disaccharidase deficiency: A single-center study from Russia.
World J Clin Cases
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Homo sapiens
Lam, MM; O'Connor, TP; Diamond, J
Loads, capacities and safety factors of maltase and the glucose transporter SGLT1 in mouse intestinal brush border.
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Mus musculus
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Effects of laser radiation on Rhus vernicifera laccase, Type 2 Cu-depleted laccase, and stellacyanin.
J Inorg Biochem
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Toxicodendron vernicifluum
Nathan, DF; Burkhart, SR; Morin, MJ
Increased cell surface EGF receptor expression during the butyrate-induced differentiation of human HCT-116 colon tumor cell clones.
Exp Cell Res
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Homo sapiens
Rhoads, JM; Corl, BA; Harrell, R; Niu, X; Gatlin, L; Phillips, O; Blikslager, A; Moeser, A; Wu, G; Odle, J
Intestinal ribosomal p70(S6K) signaling is increased in piglet rotavirus enteritis.
Am J Physiol Gastrointest Liver Physiol
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Rotavirus, Sus scrofa, Porcine rotavirus
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Expression of human intestinal mRNA transcripts during development: analysis by a semiquantitative RNA polymerase chain reaction method.
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Homo sapiens
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Lamina, Oryctolagus cuniculus
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Distribution of activity of hydrolytic enzymes in the digestive tract of rabbits.
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Homo sapiens
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Acipenser sturio, Acipenser transmontanus, Chondrichthyes, Zea mays subsp. mays
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Homo sapiens
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Rattus
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Rattus
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Homo sapiens
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Homo sapiens
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Prostaglandin E2 accelerates enzymatic and morphological maturation of the small intestine in suckling rats.
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Rattus, Rodentia
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Homo sapiens, Electron
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Escherichia coli, Metazoa, Bacteria
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Suidae
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Rattus
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Suidae, Homo sapiens
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Mustela lutreola, Felis catus, Metazoa, Mammalia
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54
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Homo sapiens, Transformation
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Folia Microbiol (Praha)
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1998
Mus sp., Rattus, Homo sapiens, animal, Suidae
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Differential effect of Bacillus firmus on immune response and enterocyte brush-border enzyme levels in BALB/c and B10.BR mice.
Folia Microbiol (Praha)
47
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2002
Mus sp., Cytobacillus firmus, Mus musculus, bacterium
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Vitamin A deficiency leads to severe functional disturbance of the intestinal epithelium enzymes associated with diarrhoea and increased bacterial translocation in gnotobiotic rats.
Microbes Infect
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Rattus
Bhalla, S; Kaur, K; Mahmood, S; Mahmood, A
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Rattus
Abramov, VM; Kosarev, IV; Priputnevich, TV; Machulin, AV; Abashina, TN; Chikileva, IO; Donetskova, AD; Takada, K; Melnikov, VG; Vasilenko, RN; Khlebnikov, VS; Samoilenko, VA; Nikonov, IN; Sukhikh, GT; Uversky, VN; Karlyshev, AV
S-layer protein 2 of vaginal Lactobacillus crispatus 2029 enhances growth, differentiation, VEGF production and barrier functions in intestinal epithelial cell line Caco-2.
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2021
Proteobacteria
García, JI; Kelley, HV; Meléndez, J; de León, RAA; Castillo, A; Sidiki, S; Yusoof, KA; Nunes, E; Téllez, CL; Mejía-Villatoro, CR; Ikeda, J; García-Basteiro, AL; Wang, SH; Torrelles, JB
Improved Alere Determine Lipoarabinomannan Antigen Detection Test for the Diagnosis of Human and Bovine Tuberculosis by Manipulating Urine and Milk.
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2019
Homo sapiens, Bos taurus
Sastry, KV; Gupta, PK
Alternations in the activity of some digestive enzymes of Channa punctatus, exposed to lead nitrate.
Bull Environ Contam Toxicol
19
549-55
1978
Channa punctata
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Oral administration recombinant porcine epidermal growth factor enhances the jejunal digestive enzyme genes expression and activity of early-weaned piglets.
J Anim Physiol Anim Nutr (Berl)
92
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2008
Sus scrofa, Suidae
van Ooyen, AJ; Dekker, P; Huang, M; Olsthoorn, MM; Jacobs, DI; Colussi, PA; Taron, CH
Heterologous protein production in the yeast Kluyveromyces lactis.
FEMS Yeast Res
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Bos taurus
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Enzymatic activities in jejunal biopsy specimens from patients with the stagnant-loop syndrome.
Scand J Gastroenterol
18
599-602
1983
Homo sapiens
Andersen, KJ; Schjønsby, H; Skagen, DW
Enzyme activities in human and rat jejunal mucosa.
Scand J Gastroenterol
18
241-9
1983
Homo sapiens, Rattus
Horvath, K; Jami, M; Hill, ID; Papadimitriou, JC; Magder, LS; Chanasongcram, S
Isocaloric glutamine-free diet and the morphology and function of rat small intestine.
JPEN J Parenter Enteral Nutr
20
128-34
0
Electron, Rattus
Hamden, K; Jaouadi, B; Zaraî, N; Rebai, T; Carreau, S; Elfeki, A
Inhibitory effects of estrogens on digestive enzymes, insulin deficiency, and pancreas toxicity in diabetic rats.
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67
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2011
Rattus
Wang, CL; Lang, X; Wu, PJ; Casper, DP; Li, FD
Development of small intestinal enzyme activities and their relationship with some gut regulatory peptides in grazing sheep.
J Anim Sci
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3783-3791
2017
Ovis aries
Owagboriaye, F; Dedeke, G; Ademolu, K; Olujimi, O; Aladesida, A; Adeleke, M
Comparative studies on endogenic stress hormones, antioxidant, biochemical and hematological status of metabolic disturbance in albino rat exposed to roundup herbicide and its active ingredient glyphosate.
Environ Sci Pollut Res Int
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2019
Rattus
Mahmood, A; Agarwal, N; Sanyal, S; Subrahmanyam, D
Effects of DDT (chlorophenotane) administration on glucose uptake and brush border enzymes in monkey intestine.
Acta Pharmacol Toxicol (Copenh)
43
99-102
1978
Platyrrhini
Hartmann, K; Gossrau, R
[Postnatal development of the epithelium of the small intestine of guinea-pigs (author's transl)]
Prog Histochem Cytochem
11
1-67
1978
Cavia
Seetharam, B; Yeh, KY; Moog, F; Alpers, DH
Development of intestinal brush border membrane proteins in the rat.
Biochim Biophys Acta
470
424-36
1977
Metazoa
Raul, F; Simon, PM; Kedinger, M; Grenier, JF; Haffen, K
Separation and characterization of intestinal brush border enzymes in adult rats and in suckling rats under normal conditions and after hydrocortisone injections.
Enzyme
23
89-97
1978
Rattus
Nelson, LM; Carmichael, HA; Russell, RI; Lee, FD
Small-intestinal changes induced by an elemental diet (Vivonex) in normal rats.
Clin Sci Mol Med
55
509-11
1978
Rattus
Morgan, KT; Coop, RL; Doxey, DL
Amprolium poisoning of preruminant lambs: an investigation of the encephalopathy and the haemorrhagic and diarrhoeic syndromes.
J Pathol
116
73-81
1975
Ovis aries
Bernard, A; Caselli, C; Blond, JP; Carlier, H
Diet fatty acid composition, age and rat jejunal microvillus enzyme activities.
Comp Biochem Physiol Comp Physiol
101
607-12
1992
Rattus
Hodin, RA; Chamberlain, SM; Upton, MP
Thyroid hormone differentially regulates rat intestinal brush border enzyme gene expression.
Gastroenterology
103
1529-36
1992
Rattus, animal
Sanyal, SN; Jamba, L; Channan, M
Effect of the antiprotozoal agent metronidazole (Flagyl) on absorptive and digestive functions of the rat intestine.
Ann Nutr Metab
36
235-43
1992
Rattus, Metazoa
Gupta, R; Jaswal, VM; Meenu Mahmood, A
Intestinal epithelial cell surface glycosylation in mice. I. Effect of high-protein diet.
Ann Nutr Metab
36
288-95
1992
Mus sp., Arachis hypogaea, Ulex europaeus, Triticum aestivum
Holt, PR; Heller, TD; Richardson, AG
Food restriction retards age-related biochemical changes in rat small intestine.
J Gerontol
46
B89-94
1991
Rattus, Metazoa
Hong, ST; Yu, JR; Myong, NH; Chai, JY; Lee, SH
Activities of brush border membrane bound enzymes of the small intestine in Metagonimus yokogawai infection in mice.
Kisaengchunghak Chapchi
29
9-20
1991
Mus sp.
Bertone, AL; Toofanian, F; Stashak, TS
Alteration of intestinal enzyme activities associated with extensive large-colon resection in horses.
Am J Vet Res
51
1329-34
1990
Equidae
Ullrich, R; Zeitz, M; Heise, W; L'age, M; Höffken, G; Riecken, EO
Small intestinal structure and function in patients infected with human immunodeficiency virus (HIV): evidence for HIV-induced enteropathy.
Ann Intern Med
111
15-21
1989
Homo sapiens
Colony, PC; Kois, JM; Peiffer, LP
Structural and enzymatic changes during colonic maturation in the fetal and suckling rat.
Gastroenterology
97
338-47
1989
Electron, Rattus
Niederst, C; Dauça, M
[Activity of renal hydrolases in pre- and postnatal development of mice]
Can J Physiol Pharmacol
63
731-4
1985
Mus musculus
Collins, J; Starkey, WG; Wallis, TS; Clarke, GJ; Worton, KJ; Spencer, AJ; Haddon, SJ; Osborne, MP; Candy, DC; Stephen, J
Intestinal enzyme profiles in normal and rotavirus-infected mice.
J Pediatr Gastroenterol Nutr
7
264-72
0
Homo sapiens, Murine rotavirus, Mus musculus, Mus sp.
Wilson, HD; Miller, T; Ogesen, B; Schedl, HP; Failla, ML; Loven, DP
Adaptation of the duodenum and ileum of the rat to mid-gut resection: enzyme activity and trace metal status.
Am J Clin Nutr
43
185-93
1986
Rattus
Weesner, RE; Kolinjivadi, J; Giannella, RA; Huitger-O'Connor, T; Genta, RM
Effect of Strongyloides ratti on small bowel function in normal and immunosuppressed host rats.
Dig Dis Sci
33
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1988
Rattus, Streptococcus ratti
Rakhimov, KR; Demidova, AI; Sakhilov, GA
[Enzyme systems of intraluminal and membrane hydrolysis of food substances in growing, adult and old rats]
Fiziol Zh SSSR Im I M Sechenova
71
998-1004
1985
Rattus
Holt, PR; Tierney, AR; Kotler, DP
Delayed enzyme expression: a defect of aging rat gut.
Gastroenterology
89
1026-34
1985
Metazoa
Smith, MW
Selective expression of brush border hydrolases by mouse Peyer's patch and jejunal villus enterocytes.
J Cell Physiol
124
219-25
1985
Mus musculus, Mus sp.
Majumdar, AP
Postnatal undernutrition: effect of epidermal growth factor on growth and function of the gastrointestinal tract in rats.
J Pediatr Gastroenterol Nutr
3
618-25
1984
Rattus
Andersen, KJ; Schjønsby, H; Skagen, DW; Haga, HJ
Enzyme activities in jejunal biopsy samples from patients with adult coeliac disease with and without steatorrhoea.
Scand J Gastroenterol
18
365-8
1983
Homo sapiens
Majumdar, AP; Rehfeld, JF
Effect of hydrocortisone on gastrin cell function in various tissues of suckling rats.
Digestion
27
165-73
1983
Rattus
Lebenthal, E; Nitzan, M; Lee, PC; Chrzanowski, BL; Krasner, J
Effect of intrauterine growth retardation on the activities of fetal intestinal enzymes in rats.
Biol Neonate
39
14-21
1981
Rattus
Mahmood, A; Agarwal, N; Sanyal, S; Dudeja, PK; Subrahmanyam, D
Acute dieldrin toxicity: effect on the uptake of glucose and leucine and on brush border enzymes in monkey intestine.
Chem Biol Interact
37
165-70
1981
Macaca mulatta, Metazoa
Ansari, S; Dudeja, PK; Mahmood, A
Effect of folate deficiency on the digestive and absorptive functions of intestinal epithelium in rats.
Acta Vitaminol Enzymol
3
12-6
1981
Metazoa
Pathak, RM; Dudeja, PK; Ansari, S; Mahmood, A
Alterations in intestinal function in response to thyroxine and cortisone administration in undernourished rats.
Ann Nutr Metab
26
331-6
1982
Rattus, Metazoa
Anand, BS; Mahmood, A; Ganguly, NK; Rehani, MM; Dilawari, JB; Mahajan, RC
Transport studies and enzyme assays in mice infected with human Giardia lamblia.
Trans R Soc Trop Med Hyg
76
616-9
1982
Metazoa
Carter, EA; Bloch, KJ; Cohen, S; Isselbacher, KJ; Walker, WA
Use of hydrogen gas (H2) analysis to assess intestinal absorption. Studies in normal rats and in rats infected with the nematode, Nippostrongylus brasiliensis.
Gastroenterology
81
1091-7
1981
Rattus
Chowdhury, JS; Dudeja, PK; Mehta, SK; Mahmood, A
Effect of a single oral dose of malathion on D-glucose and glycine uptake and on brush border enzymes in rat intestine.
Toxicol Lett
6
411-5
1980
Rattus
Kaur, J; Nagpaul, JP; Mahmood, A
Expression of brush border enzymes in ethanol fed rat intestine.
Indian J Med Res
100
289-94
1994
Rattus
Zijlstra, RT; Odle, J; Hall, WF; Petschow, BW; Gelberg, HB; Litov, RE
Effect of orally administered epidermal growth factor on intestinal recovery of neonatal pigs infected with rotavirus.
J Pediatr Gastroenterol Nutr
19
382-90
1994
Suidae, Rotavirus
Albert, V; Barkla, D; Young, GP
Serum-free organ culture of suckling rat jejunum: effect of regulatory hormones.
In Vitro Cell Dev Biol Anim
30A
443-9
1994
Rattus
Hodin, RA; Meng, S; Chamberlain, SM
Thyroid hormone responsiveness is developmentally regulated in the rat small intestine: a possible role for the alpha-2 receptor variant.
Endocrinology
135
564-8
1994
Rattus, Metazoa
Hodin, RA; Meng, S; Shei, A
Bombesin maintains enterocyte phenotype in fasted rats.
Surgery
116
426-31
1994
Rattus, Metazoa
Zucoloto, S; Braulio, VB; Santos, GC; Ramalho, FS; Scandar, MP; de Freitas, O; de Oliveira, JA
Effect of chronic ethanol consumption on the activities of residual small bowel brush-border enzymes after proximal jejunum resection in the rat.
Alcohol Clin Exp Res
20
152-5
1996
Rattus, Rattus norvegicus
Jahn, HU; Ullrich, R; Schneider, T; Liehr, RM; Schieferdecker, HL; Holst, H; Zeitz, M
Immunological and trophical effects of Saccharomyces boulardii on the small intestine in healthy human volunteers.
Digestion
57
95-104
1996
Homo sapiens, Saccharomyces boulardii (nom. inval.)
Wang, T; Xu, RJ
Effects of colostrum feeding on intestinal development in newborn pigs.
Biol Neonate
70
339-48
1996
Suidae, Sus scrofa
Camps, L; Kédinger, M; Simon-Assmann, PM; López-Tejero, D
Effect of prenatal exposure to ethanol on intestinal development of rat fetuses.
J Pediatr Gastroenterol Nutr
24
302-11
1997
Rattus, Homo sapiens, Metazoa
Russo, F; De Carne, M; Buonsante, A; Cisternino, AM; Centonze, S; Giannandrea, B; Di Leo, A
Hypolactasia and metabolic changes in post-menopausal women.
Maturitas
26
193-202
1997
Homo sapiens
Zijlstra, RT; Donovan, SM; Odle, J; Gelberg, HB; Petschow, BW; Gaskins, HR
Protein-energy malnutrition delays small-intestinal recovery in neonatal pigs infected with rotavirus.
J Nutr
127
1118-27
1997
Suidae
Koivisto, T; Salaspuro, M
Effects of acetaldehyde on brush border enzyme activities in human colon adenocarcinoma cell line Caco-2.
Alcohol Clin Exp Res
21
1599-605
1997
Homo sapiens
Ménard, D; Corriveau, L; Beaulieu, JF
Insulin modulates cellular proliferation in developing human jejunum and colon.
Biol Neonate
75
143-51
1999
Homo sapiens, Rodentia
Tang, M; Laarveld, B; Van Kessel, AG; Hamilton, DL; Estrada, A; Patience, JF
Effect of segregated early weaning on postweaning small intestinal development in pigs.
J Anim Sci
77
3191-200
1999
Suidae
Timofeeva, NM; Egorova, VV; Nikitina, AA; Iezuitova, NN; Gordova, LA; Gruzdkov, AA
[Effect of protein deficiency in the female rat diet during pregnancy and lactation on the activity of the membrane and soluble forms of digestive enzymes in the offspring small intestine]
Ross Fiziol Zh Im I M Sechenova
85
1567-73
1999
Rattus
González, M; Caride, B; Lamas, MA; Taboada, MC
Effects of sea urchin-based diets on serum lipid composition and on intestinal enzymes in rats.
J Physiol Biochem
56
347-52
2000
Echinus esculentus, Rattus, Echinoidea, Echinus, Metazoa
Vázquez, CM; Zanetti, R; Santa-MarÃa, C; RuÃz-Gutiérrez, V
Effects of two highly monounsaturated oils on lipid composition and enzyme activities in rat jejunum.
Biosci Rep
20
355-68
2000
Rattus, Helianthus, Metazoa
Kaur, U; Kaur, S; Mahmood, A; Agnihotri, N
Activity of brush border membrane enzymes in proximal jejunum of portal hypertensive rats.
J Gastroenterol
36
407-9
2001
Metazoa, Rattus
Labana, S; Bansal, RC; Mahmood, A
Age related effects of organochlorine insecticide lindane on intestinal brush border membrane in rats.
Indian J Biochem Biophys
38
249-52
2001
Rattus, Metazoa
Bujanover, Y; Wollman, Y; Reif, S; Golander, A
A possible role of prolactin on growth and maturation of the gut during development in the rat.
J Pediatr Endocrinol Metab
15
789-94
2002
Rattus
Rana, S; Gupta, D; Katyal, R; Singh, K
Effect of malnutrition on the digestive enzymes of the upper gastrointestinal tract of young rhesus monkeys.
Trop Gastroenterol
24
22-4
0
Macaca mulatta, Platyrrhini
Rana, S
Effects of malnutrition on the digestive enzymes of the large bowel of young rhesus monkeys.
Trop Gastroenterol
24
189-92
0
Macaca mulatta
Kapur, P; Kaur, K; Mahmood, A
Expression of brush border enzymes in response to lead exposure in rat intestine.
J Appl Toxicol
25
361-4
0
Rattus
Singla, A; Kaur, J; Mahmood, A
Alterations in the expression of intestinal enzymes in rats exposed to nickel.
J Appl Toxicol
26
397-401
0
Metazoa
Schaart, MW; Yamanouchi, T; van Nispen, DJ; Raatgeep, RH; van Goudoever, JB; de Krijger, RR; Tibboel, D; Einerhand, AW; Renes, IB
Does small intestinal atresia affect epithelial protein expression in human newborns?
J Pediatr Gastroenterol Nutr
43
576-83
2006
Homo sapiens
Hudcovic, T; Kozáková, H; KolÃnská, J; StÄ›pánková, R; HrnÄÃÅ™, T; Tlaskalová-Hogenová, H
Monocolonization with Bacteroides ovatus protects immunodeficient SCID mice from mortality in chronic intestinal inflammation caused by long-lasting dextran sodium sulfate treatment.
Physiol Res
2008
Mus sp., Bacteroides, Bacteroides ovatus, Mus musculus, bacterium
Shekherdimian, S; Scott, A; Chan, A; Dunn, JC
Intestinal lengthening in rats after massive small intestinal resection.
Surgery
146
291-5
2009
Rattus, Homo sapiens, Metazoa
Gera, N; Kiran, R; Mahmood, A
Subacute effects of carbofuran on enzyme functions in rat small intestine.
Toxicol Mech Methods
19
141-7
2009
Metazoa
Vir, P; Kaur, J; Mahmood, A
Effect of chronic iron ingestion on the development of brush border enzymes in rat intestine.
Toxicol Mech Methods
17
393-9
2007
Metazoa
Kalischuk, LD; Leggett, F; Inglis, GD
Campylobacter jejuni induces transcytosis of commensal bacteria across the intestinal epithelium through M-like cells.
Gut Pathog
2
14
2010
Ulex europaeus
Harpaz S;Hakim Y;Slosman T;Eroldogan OT
Effects of adding salt to the diet of Asian sea bass Lates calcarifer reared in fresh or salt water recirculating tanks, on growth and brush border enzyme activity.
Aquaculture (Amsterdam, Netherlands)
248
315-324
2005
Chondrichthyes
Giudicelli, J; Rigat, AM; Sudaka, P
[Electrofocusing of hydrolases in rat brush border enterocytes]
C R Seances Soc Biol Fil
169
372-9
1975
Rattus
Healy, PJ
Intestinal brush border and lysosomal enzymes and immunoglobulin absorption in the newly-born lamb.
Aust J Exp Biol Med Sci
55
327-37
1977
Ovis aries
Cellesi, C; Rossolini, GM; Lusini, P; Gerli, R; Alessandrini, C
[Enzyme activity and ultrastructure of the intestinal epithelium in mice treated with rifampicin]
Boll Ist Sieroter Milan
64
150-4
1985
Metazoa
Lee, PC; Struve, M; Raff, H
Effects of hypoxia on the development of intestinal enzymes in neonatal and juvenile rats.
Exp Biol Med (Maywood)
228
717-23
2003
Rattus
Sauer, N; Eklund, M; Roth, S; Rink, F; Jezierny, D; Bauer, E; Mosenthin, R
Short-term effect of dietary yeast nucleotide supplementation on small intestinal enzyme activities, bacterial populations and metabolites and ileal nutrient digestibilities in newly weaned pigs*
J Anim Physiol Anim Nutr (Berl)
2011
Saccharomyces cerevisiae
Sauer, N; Eklund, M; Hoerner, S; Bauer, E; Jezierny, D; Mosenthin, R
Short-term effect of dietary yeast nucleotide supplementation on total and diurnal variation of small intestinal enzyme activities in piglets.
J Anim Sci
90 Suppl 4
179-81
2012
Saccharomyces cerevisiae
Krogdahl A;Sundby A;Olli JJ
Atlantic salmon (Salmo salar) and rainbow trout (Oncorhynchus mykiss) digest and metabolize nutrients differently. Effects of water salinity and dietary starch level.
Aquaculture (Amsterdam, Netherlands)
229
335-360
2004
Oncorhynchus mykiss, Salmo salar
Kozáková, H; StÄ•pánková, R; Reháková, Z; KolÃnská, J
Differences in enterocyte brush border enzyme activities in ageing rats reared in germ-free and conventional conditions.
Physiol Res
47
253-8
1998
Rattus
Giglio, L; Candusso, M; D'Orazio, C; Mastella, G; Faraguna, D
Failure to thrive: the earliest feature of cystic fibrosis in infants diagnosed by neonatal screening.
Acta Paediatr
86
1162-5
1997
Homo sapiens
Wu, H; Xuan, R; Li, Y; Zhang, X; Wang, Q; Wang, L
Effects of cadmium exposure on digestive enzymes, antioxidant enzymes, and lipid peroxidation in the freshwater crab Sinopotamon henanense.
Environ Sci Pollut Res Int
2012
Longpotamon honanense
Trotta, RJ; Keomanivong, FE; Peine, JL; Caton, JS; Swanson, KC
Influence of maternal nutrient restriction and rumen-protected arginine supplementation on post-ruminal digestive enzyme activity of lamb offspring.
Livest Sci
241
2020
Ovis aries
Tsuboi, KK; Schwartz, SM; Burrill, PH; Kwong, LK; Sunshine, P
Sugar hydrolases of the infant rat intestine and their arrangement of the brush border membrane.
Biochim Biophys Acta
554
234-48
1979
Rattus
Tsuboi, KK; Kwong, LK; Burrill, PH; Sunshine, P
Sugar hydrolases and their arrangement on the rat intestinal microvillus membrane.
J Membr Biol
50
101-22
1979
Rattus
Boza, J; Jiménez, J; Baró, L; MartÃnez, O; Suárez, MD; Gil, A
Effects of native and hydrolyzed whey protein on intestinal repair of severely starved rats at weaning.
J Pediatr Gastroenterol Nutr
22
186-93
1996
Metazoa, Rattus, Rattus norvegicus
Katz, JP; Perreault, N; Goldstein, BG; Chao, HH; Ferraris, RP; Kaestner, KH
Foxl1 null mice have abnormal intestinal epithelia, postnatal growth retardation, and defective intestinal glucose uptake.
Am J Physiol Gastrointest Liver Physiol
287
G856-64
2004
Mus sp.
Kushak, RI; Buie, TM; Murray, KF; Newburg, DS; Chen, C; Nestoridi, E; Winter, HS
Evaluation of Intestinal Function in Children with Autism and Gastrointestinal Symptoms.
J Pediatr Gastroenterol Nutr
2016
Homo sapiens
Li, Y; Nguyen, DN; Ryom, K; Andersen, AD; Thymann, T; Chatterton, DEW; Purup, S; Heckmann, AB; Bering, SB; Sangild, PT
Bioactive Whey Protein Concentrate and Lactose Stimulate Gut Function in Formula-Fed Preterm Pigs.
J Pediatr Gastroenterol Nutr
2017
Suidae
Alliende, F; Vial, C; Espinoza, K; Schnettle, D; Romero, V; Miquel, I; Arancibia, ME; Rios, G; Rodriguez, L; Quesada, S; Lucero, Y; Repetto, GM
Accuracy of A Genetic Test for the Diagnosis of Hypolactasia in Chilean Children: Comparison with the Breath Test.
J Pediatr Gastroenterol Nutr
2016
Homo sapiens
Henning, SJ
Plasma concentrations of total and free corticosterone during development in the rat.
Am J Physiol
235
E451-6
1978
Metazoa
Younoszai, MK; Ranshaw, J
Intestinal disaccharidases in the rat: effects of pregnancy and diabetes.
J Nutr
106
504-8
1976
Rattus
Toofanian, F; Aliakbari, S
Studies on the digestion of carbohydrates in the camel (Camelus dromedarius).
Trop Anim Health Prod
9
233-7
1977
Camelus bactrianus
Potier, M; Melancon, SB; Dallaire, L
Developmental patterns of intestinal disaccharidases in human amniotic fluid.
Am J Obstet Gynecol
131
73-6
1978
Homo sapiens
Watanabe, H
Experimentally induced intestinal metaplasia in Wistar rats by X-ray irradiation.
Gastroenterology
75
796-9
1978
Rattus
Brasil, MR; Collares, EF; Soares, FC
[Insulin and disaccharidases levels of the small intestine of the rat (author's transl)]
Arq Gastroenterol
15
141-5
0
Rattus, Rattus norvegicus
Palit, MM; Dasgupta, SR; Dutta, D; Sharma, AK; Sarkar, S
Comparative studies on different small intestinal oligosaccharidase activities in some vertebrates and invertebrates like molluscs.
Indian J Physiol Pharmacol
20
156-9
0
vertebrata, Rattus, Calotes versicolor, toad
Valenkevich, LN; Zhikova, NM
[Activity of intestinal disaccharidases in human aging]
Vopr Pitan
9-11
0
Homo sapiens
Hernandez, A; Martinez del Rio, C
Intestinal disaccharidases in five species of phyllostomoid bats.
Comp Biochem Physiol B
103
105-11
1992
Chiroptera, Trochilidae, Glossophaga, Sturnira, Pelecorhynchus personatus
Castillo, RO; Feng, JJ; Stevenson, DK; Kwong, LK
Maturation of jejunoileal gradients in rat intestine: the role of intraluminal nutrients.
Biol Neonate
62
351-62
1992
Rattus, Metazoa
Yeh, KY; Yeh, M; Holt, PR
Thyroxine and cortisone cooperate to modulate postnatal intestinal enzyme differentiation in the rat.
Am J Physiol
260
G371-8
1991
Rattus, animal
Dunsford, BR; Haensly, WE
Effect of dietary cholesterol and carbohydrate on small intestinal structure and function in prematurely weaned rats.
J Anim Sci
69
2894-903
1991
Rattus, Sus scrofa, Metazoa
Richter, T; Niemann, E; Beyreiss, K
[Comparative studies of the activity of disaccharidases in the mucosa of the small intestines in dystrophic, formerly hypotrophic-born young children and of patients with flat mucosa of various etiology]
Kinderarztl Prax
59
273-7
1991
Homo sapiens
Gabriel, EP; Lindquist, BL; Abud, RL; Merrick, JM; Lebenthal, E
Effect of vitamin A deficiency on the adherence of fimbriated and nonfimbriated Salmonella typhimurium to isolated small intestinal enterocytes.
J Pediatr Gastroenterol Nutr
10
530-5
1990
Rattus
Jaeger, LA; Lamar, CH; Cline, TR; Cardona, CJ
Effect of orally administered epidermal growth factor on the jejunal mucosa of weaned pigs.
Am J Vet Res
51
471-4
1990
Suidae, Sus scrofa
Nuñez, MC; Ayudarte, MV; Morales, D; Suarez, MD; Gil, A
Effect of dietary nucleotides on intestinal repair in rats with experimental chronic diarrhea.
JPEN J Parenter Enteral Nutr
14
598-604
0
Rattus, Metazoa
Takeuchi, M; Takai, N; Asano, N; Kameda, Y; Matsui, K
Inhibitory effect of validamine, valienamine and valiolamine on activities of carbohydrases in rat small intestinal brush border membranes.
Chem Pharm Bull (Tokyo)
38
1970-2
1990
Rattus, Streptomyces hygroscopicus subsp. limoneus
Ford, WD; Kleinman, RE; King, WW; de Vries, JE; Boelhouwer, RU; Ross, JS; Malt, RA
Intestinal resection in the neonatal rat: stimulus for precocious intestinal maturation.
J Pediatr Gastroenterol Nutr
4
628-33
1985
Rattus, Metazoa
Tsuboi, KK; Kwong, LK; Yamada, K; Sunshine, P; Koldovsky, O
Nature of elevated rat intestinal carbohydrase activities after high-carbohydrate diet feeding.
Am J Physiol
249
G510-8
1985
Rattus
Firmansyah, A; Sunoto, ; Suharyono,
Effect of malnutrition during different periods on the small intestine of the rat.
Jpn J Exp Med
59
1-7
1989
Rattus
Shimada, T; Hoshi, T
A comparative study of specificity of the intestinal Na+/sugar cotransport among vertebrates.
Comp Biochem Physiol A
84
365-70
1986
Metazoa
Tsuboi, KK; Kwong, LK; Fan, Q; Thompson, DJ; D'Harlingue, AE; Sunshine, P
Effects of hydrocortisone on carbohydrase concentrations, de novo synthesis and turnover patterns in immature rat intestine.
Cell Biochem Funct
4
131-42
1986
Rattus
Wen, D; Henning, SJ; Hazelwood, RL
Effects of diabetes on development of small intestinal enzymes of infant rats.
Proc Soc Exp Biol Med
187
51-7
1988
Rattus
Dufour, C; Dandrifosse, G; Forget, P; Vermesse, F; Romain, N; Lepoint, P
Spermine and spermidine induce intestinal maturation in the rat.
Gastroenterology
95
112-6
1988
Rattus
Inagaki, O; Fujita, Y; Inoue, S; Mori, H; Gomikawa, S; Yorifuji, R; Hirabayashi, T
Effect of 1,25-dihydroxyvitamin D3 on intestinal disaccharidases in uremic rats.
Nephron
44
75-7
1986
Rattus
Dinari, G; Cohen, MI; McNamara, H; Daum, F
The effect of phototherapy on intestinal mucosal enzyme activity in the Gunn rat.
Biol Neonate
38
179-84
1980
Rattus norvegicus
Sir El Khatim, MM; Osman, AM
The level and distribution of disaccharidases in the camel (Camelus dromedarius) intestine.
Comp Biochem Physiol A
71
199-204
1982
Camelus bactrianus
Oka, Y; Ghishan, FK; Greene, HL; Orth, DN
Effect of mouse epidermal growth factor/urogastrone on the functional maturation of rat intestine.
Endocrinology
112
940-4
1983
Mus musculus, Rattus
Buts, JP; Delacroix, DL; Dekeyser, N; Paquet, S; Horsmans, Y; Boelens, M; Van Craynest, MP; De Meyer, R
Role of dietary iron in maturation of rat small intestine at weaning.
Am J Physiol
246
G725-31
1984
Rattus
Majumdar, AP
Effect of adrenalectomy and tryptophan force-feeding on the activity of intestinal disaccharidases in adult rats.
Scand J Gastroenterol
15
225-8
1980
Rattus
Jambunathan, LR; Neuhoff, D; Younoszai, MK
Intestinal disaccharidases in malnourished infant rats.
Am J Clin Nutr
34
1879-84
1981
Homo sapiens
Kidder, DE; Manners, MJ
The level of distribution of carbohydrases in the small intestine mucosa of pigs from 3 weeks of age to maturity.
Br J Nutr
43
141-53
1980
Suidae
Gall, DG; Chung, M
Effect of body weight on postnatal development of the proximal small intestine of the rabbit.
Biol Neonate
42
159-65
1982
Metazoa
Ulbrich, M; Hakim, NF; Hoffmann, M
[Studies of the activity of disaccharides in growing sheep. 2. The influence of the feeding regime on the activity of disaccharidases in lambs up to the age of 4 weeks under various rearing conditions]
Arch Tierernahr
30
841-52
1980
Ovis aries
Onning, G; Asp, NG
Effect of oat saponins and different types of dietary fibre on the digestion of carbohydrates.
Br J Nutr
74
229-37
1995
Avena sp.
Yoshinaga, K; Ishizuka, J; Townsend, CM; Thompson, JC
Age-related changes in duodenal adaptation after distal small bowel resection in rat.
Dig Dis Sci
38
410-6
1993
Rattus
Kanwar, SS; Singh, V; Vinayak, VK; Malik, AK; Mehta, SK; Mehta, S
Differential tropism of EB rotavirus (serotype 3) to small intestine of homologous murine model.
Acta Virol
38
269-76
1994
Mus musculus, Rotavirus, Mus sp.
Maiuri, L; Rossi, M; Raia, V; Paparo, F; Coletta, S; Mazzeo, F; Breglia, A; Auricchio, S
Morphological method for the diagnosis of human adult type hypolactasia.
Gut
35
1042-6
1994
Homo sapiens
Kozakova, H; Mandel, L; Trebichavsky, I; Kolinska, J; Barot-Ciorbaru, R
Protective effects of Nocardia delipidated cell mitogen on the mucosa of the small intestine after irradiation of germ-free piglets.
Cell Biol Int
18
237-43
1994
Nocardia
Sinha, M; Ghosh, AK
Effect of hypervitaminosis A on intestinal digestive & absorptive functions in rat.
Indian J Med Res
99
133-6
1994
Metazoa
Wéry, I; Dandrifosse, G
Evolution of biochemical parameters characterizing the proximal small intestine after orally administered spermine in unweaned rats.
Endocr Regul
27
201-7
1993
Rattus
Zheng, BY; Khin-Maung-U, ; Lu, RB; Maiese, RL; Lebenthal, E
Effect of perfusion of oral rehydration solutions containing glucose polymers from corn on disaccharidases and mucosal morphology in rat small intestines.
J Trop Pediatr
40
179-84
1994
Rattus, Zea mays subsp. mays
Shaheen, AA; Hassan, SH
Role of vitamin A in modulating the radiation-induced changes in intestinal disaccharidases of rats exposed to multifractionated gamma-radiations.
Strahlenther Onkol
170
467-70
1994
Rattus
Berant, M; Diamond, E; Mabriki, W; Ben-Yitzhak, O
Effects of hypothyroidism on jejunal mucosal function: study by in situ luminal perfusion in rats.
Pediatr Res
34
79-83
1993
Rattus
Rakhimov, KR; Demidova, AI; Usmanova, OD; Shinder, DA
[The physiological mechanisms of the delay in the functional maturation of the small intestine in rat pups prematurely switched from milk to definitive nutrition]
Fiziol Zh Im I M Sechenova
79
87-92
1993
Rattus
Olanrewaju, HA; Sanzenbacher, ED; Seidel, ER
Insulin-like growth factor I in suckling rat gastric contents.
Dig Dis Sci
41
1392-7
1996
Rattus, Homo sapiens, Metazoa
Kaouass, M; Deloyer, P; Wery, I; Dandrifosse, G
Analysis of structural and biochemical events occurring in the small intestine after dietary polyamine ingestion in suckling rats.
Dig Dis Sci
41
1434-44
1996
Rattus, Metazoa
Buddington, RK; Malo, C
Intestinal brush-border membrane enzyme activities and transport functions during prenatal development of pigs.
J Pediatr Gastroenterol Nutr
23
51-64
1996
Homo sapiens, Suidae, Sus scrofa
Deloyer, P; Dandrifosse, G; Bartholomeus, C; Romain, N; Klimek, M; Salmon, J; Gérard, P; Goessens, G
Polyamine and intestinal properties in adult rats.
Br J Nutr
76
627-37
1996
Rattus, Metazoa
Zhang, H; Malo, C; Buddington, RK
Suckling induces rapid intestinal growth and changes in brush border digestive functions of newborn pigs.
J Nutr
127
418-26
1997
insertion sequences, Suidae
Gómez, S; Angeles, ML; Cuarón, JA
Growth performance and enzyme development in weanling pigs injected with dexamethasone.
J Anim Sci
75
993-1000
1997
Suidae
Kaouass, M; Deloyer, P; Dandrifosse, G
Involvement of bombesin in spermine-induced corticosterone secretion and intestinal maturation in suckling rats.
J Endocrinol
153
429-36
1997
Rattus
ter Steege, JC; Buurman, WA; Forget, PP
Spermine induces maturation of the immature intestinal immune system in neonatal mice.
J Pediatr Gastroenterol Nutr
25
332-40
1997
Mus sp., Mus musculus, Rattus, Lamina
Miura, T; Koide, T; Ohichi, R; Kako, M; Usami, M; Ishihara, E; Yasuda, N; Ishida, H; Seino, Y; Tanigawa, K
Effect of acarbose (alpha-glucosidase inhibitor) on disaccharase activity in small intestine in KK-Ay and ddY mice.
J Nutr Sci Vitaminol (Tokyo)
44
371-9
1998
Mus sp.
Kit, S; Thomson, AB; Clandinin, MT
Diet fat and oral insulin-like growth factor influence the membrane fatty acid composition of suckling rat small intestine.
J Pediatr Gastroenterol Nutr
29
18-25
1999
Rattus
Vieira, MR; Galvão, LC; Fernandes, MI
Relation of the disaccharidases in the small intestine of the rat to the degree of experimentally induced iron-deficiency anemia.
Braz J Med Biol Res
33
539-44
2000
Metazoa
Lhatoo, SD; Bhasin, DK; Rana, SV; Katyal, R; Singh, K
Effect of alcohol dependence on the levels of duodenal disaccharidases in human subjects.
Indian J Physiol Pharmacol
44
495-9
2000
Homo sapiens
Kaura, D; Bhasin, DK; Rana, SV; Katyal, R; Vaiphei, K; Singh, K
Alterations in duodenal disaccharidases in chronic smokers.
Indian J Gastroenterol
20
62-3
0
Homo sapiens
Odetola, AA; Akojenu, SM
Anti-diarrhoeal and gastro-intestinal potentials of the aqueous extract of Phyllanthus amarus (Euphorbiaceae).
Afr J Med Med Sci
29
119-22
2000
Mus sp., Castor, Phyllanthus amarus, plant
Dyer, J; Wood, IS; Palejwala, A; Ellis, A; Shirazi-Beechey, SP
Expression of monosaccharide transporters in intestine of diabetic humans.
Am J Physiol Gastrointest Liver Physiol
282
G241-8
2002
Homo sapiens
Dyer, J; Fernandez-Castaño Merediz, E; Salmon, KS; Proudman, CJ; Edwards, GB; Shirazi-Beechey, SP
Molecular characterisation of carbohydrate digestion and absorption in equine small intestine.
Equine Vet J
34
349-58
2002
Equus caballus
Chethankumar, M; Salimath, PV; Sambaiah, K
Butyric acid modulates activities of intestinal and renal disaccharidases in experimentally induced diabetic rats.
Nahrung
46
345-8
2002
Rattus
Sabat, P; Veloso, C
Ontogenic development of intestinal disaccharidases in the precocial rodent Octodon degus (Octodontidae).
Comp Biochem Physiol A Mol Integr Physiol
134
393-7
2003
Rodentia, Octodon degus
Nanthakumar, NN; Klopcic, CE; Fernandez, I; Walker, WA
Normal and glucocorticoid-induced development of the human small intestinal xenograft.
Am J Physiol Regul Integr Comp Physiol
285
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2003
Homo sapiens, Mus sp.
Rasinperä, H; Savilahti, E; Enattah, NS; Kuokkanen, M; Tötterman, N; Lindahl, H; Järvelä, I; Kolho, KL
A genetic test which can be used to diagnose adult-type hypolactasia in children.
Gut
53
1571-6
2004
Homo sapiens, Pierinae
Rebollara, PG; Espinosaa, A; Lorenzo, PL; Carabaño, R
Transitory disturbances in growing lactating rabbits after transient doe-litter separation.
Reprod Nutr Dev
44
437-47
0
Oryctolagus cuniculus
Ramachandra, R; Shetty, AK; Salimath, PV
Quercetin alleviates activities of intestinal and renal disaccharidases in streptozotocin-induced diabetic rats.
Mol Nutr Food Res
49
355-60
2005
Rattus
Elemo, BO
Comparative effects of osmotic and secretory diarrhoea on brush-border disaccharide hydrolases in rat.
Afr J Med Med Sci
33
293-8
2004
Rattus, Salmonella enterica subsp. enterica serovar Typhimurium
Kumar Shetty, A; Suresh Kumar, G; Veerayya Salimath, P
Bitter gourd (Momordica charantia) modulates activities of intestinal and renal disaccharidases in streptozotocin-induced diabetic rats.
Mol Nutr Food Res
49
791-6
2005
Momordica charantia, Rattus, Metazoa
Kumar, GS; Shetty, AK; Salimath, PV
Modulatory effect of fenugreek seed mucilage and spent turmeric on intestinal and renal disaccharidases in streptozotocin induced diabetic rats.
Plant Foods Hum Nutr
60
87-91
2005
Rattus, Trigonella foenum-graecum, Curcuma longa
Qiu, XS; Huang, TT; Shen, ZY; Deng, HY; Ke, ZY
Effect of early nutrition on intestine development of intrauterine growth retardation in rats and its correlation to leptin.
World J Gastroenterol
11
4419-22
2005
Rattus
Islam, S; Mitra, AK; Chowdhury, AK; Alam, NH
Intestinal enzymes during malnutrition & infection in rabbits.
Indian J Med Res
124
313-8
2006
Oryctolagus cuniculus, Escherichia coli, Metazoa
Jurgoński, A; Juśkiewicz, J; Zduńczyk, Z
Ingestion of black chokeberry fruit extract leads to intestinal and systemic changes in a rat model of prediabetes and hyperlipidemia.
Plant Foods Hum Nutr
63
176-82
2008
Photinia
JuÅ›kiewicz, J; ZduÅ„czyk, Z; JurgoÅ„ski, A; Brzuzan, Å; Godycka-KÅ‚os, I; Zary-Sikorska, E
Extract of green tea leaves partially attenuates streptozotocin-induced changes in antioxidant status and gastrointestinal functioning in rats.
Nutr Res
28
343-9
2008
Rattus
Du, D; Shi, YH; Le, GW
Microarray analysis of high-glucose diet-induced changes in mRNA expression in jejunums of C57BL/6J mice reveals impairment in digestion, absorption.
Mol Biol Rep
2009
Mus sp.
Schmitz, H
ENZYME ACTION IN ECHINODONTIUM TINCTORIUM ELLIS AND EVERHART.
J Gen Physiol
2
613-616
1920
Echinodontium tinctorium
Schmitz, H
STUDIES IN WOOD DECAY : II. ENZYME ACTION IN POLYPORUS VOLVATUS PECK AND FOMES IGNIARIUS (L.) GILLET.
J Gen Physiol
3
795-800
1921
Fomes, Polyporus
Deng, YX; Chen, YS; Zhang, WR; Chen, B; Qiu, XM; He, LH; Mu, LL; Yang, CH; Chen, R
Polysaccharide from Gynura divaricata modulates the activities of intestinal disaccharidases in streptozotocin-induced diabetic rats.
Br J Nutr
1-7
2011
Gynura divaricata, Rattus
Sharma, R; Kaur, J; Chauhan, SS; Mahmood, A
Gestational diabetes affects postnatal development of transport and enzyme functions in rat intestine.
Mol Cell Biochem
361
71-7
2012
Rattus
Mahmood, S; Sodhi, CP; Ganguly, NK
Expression of sodium-glucose co-transporter and brush border disaccharidases in Giardia lamblia infected rat intestine.
Indian J Biochem Biophys
39
185-90
2002
Giardia, Giardia intestinalis, Rattus
Lackeyram, D; Mine, Y; Widowski, T; Archbold, T; Fan, MZ
The in vivo infusion of hydrogen peroxide induces oxidative stress and differentially affects the activities of small intestinal carbohydrate digestive enzymes in the neonatal pig.
J Anim Sci
90 Suppl 4
418-20
2012
animal
Pinheiro, DF; Pacheco, PD; Alvarenga, PV; Buratini Jr, J; Castilho, AC; Lima, PF; Sartori, DR; Vicentini-Paulino, ML
Maternal protein restriction affects gene expression and enzyme activity of intestinal disaccharidases in adult rat offspring.
Braz J Med Biol Res
1-6
2013
Rattus
Parfenov, AI; Akhmadullina, OV; Sabel'nikova, EA; Belostotskii, NI; Gudkova, RB; Khomeriki, SG
[Carbohydrase activities may serve as a marker for small intestinal mucosal recovery in patients with celiac disease].
Ter Arkh
87
24-9
2015
Homo sapiens
Qi, KK; Wu, J; Deng, B; Li, YM; Xu, ZW
PEGylated porcine glucagon-like peptide-2 improved the intestinal digestive function and prevented inflammation of weaning piglets challenged with LPS.
Animal
9
1481-9
2015
Sus scrofa, Escherichia coli
Lee, J; Lee, HJ; Lee, JJ
Coating rice with mulberry leaves rich in deoxynojirimycin ameliorates hyperglycemia and dyslipidemia in C57BL/KsJ db/db mice.
Nutr Res Pract
12
469-478
2018
Mus sp.
Helm, ET; Curry, SM; De Mille, CM; Schweer, WP; Burrough, ER; Gabler, NK
Impact of viral disease hypophagia on pig jejunal function and integrity.
PLoS One
15
e0227265
2020
Suidae
Hui, H; Wu, Y; Zheng, T; Zhou, S; Tan, Z
Bacterial Characteristics in Intestinal Contents of Antibiotic-Associated Diarrhea Mice Treated with Qiweibaizhu Powder.
Med Sci Monit
26
e921771
2020
Mus sp.
Yu, E; Chen, D; Yu, B; Huang, Z; Mao, X; Zheng, P; Luo, Y; Yin, H; Yu, J; Luo, J; Yan, H; He, J
Manno-oligosaccharide attenuates inflammation and intestinal epithelium injury in weaned pigs upon enterotoxigenic Escherichia coli K88 challenge.
Br J Nutr
1-10
2020
Suidae
BHASKAR JJ;MAHADEVAMMA S;VISHWANATHA S;SALIMATH PV
EFFECT OF BANANA (MUSA SP. CULTIVAR ELAKKI BALE) FLOWER AND STEM ON ENZYME ACTIVITIES OF INTESTINAL AND RENAL DISACCHARIDASES IN STREPTOZOTOCIN-INDUCED DIABETIC RATS
Journal of food biochemistry
34
564-580
2010
Musa acuminata, Rattus
Kato, A; Adachi, I; Miyauchi, M; Ikeda, K; Komae, T; Kizu, H; Kameda, Y; Watson, AA; Nash, RJ; Wormald, MR; Fleet, GW; Asano, N
Polyhydroxylated pyrrolidine and pyrrolizidine alkaloids from Hyancinthoides non-scripta and Scilla campanulata.
Carbohydr Res
316
95-103
1999
Bos taurus, Rattus, Hyacinthoides hispanica, Sus scrofa, Caldicellulosiruptor saccharolyticus
Rakhimov, KR; Sadykov, BA; Allamuratov, M
[The enzyme systems of the cavitary and membrane hydrolysis of foodstuffs in the ontogeny of Karakul sheep]
Zh Evol Biokhim Fiziol
25
460-6
0
Ovis aries
Bernstein, J; Burrill, P; Kretchmer, N
Disaccharidase-deficient animals have normal ultrastructure of intestinal brush border membranes.
Cell Tissue Res
220
555-9
1981
Homo sapiens, Rattus
Ko, SR; Choi, KJ; Uchida, K; Suzuki, Y
Enzymatic preparation of ginsenosides Rg2, Rh1, and F1 from protopanaxatriol-type ginseng saponin mixture.
Planta Med
69
285-6
2003
Aspergillus oryzae, Penicillium sp.
Poley, JR
The scanning electron microscope: how valuable in the evaluation of small bowel mucosal pathology in chronic childhood diarrhea?
Scanning Microsc
5
1037-62; discussion 1062-3
1991
Homo sapiens, Rotavirus
Goda, T; Takase, S
Effect of dietary fat content on microvillus in rat jejunum.
J Nutr Sci Vitaminol (Tokyo)
40
127-36
1994
Electron, Metazoa, Rattus
Schaart, MW; de Bruijn, AC; Bouwman, DM; de Krijger, RR; van Goudoever, JB; Tibboel, D; Renes, IB
Epithelial functions of the residual bowel after surgery for necrotising enterocolitis in human infants.
J Pediatr Gastroenterol Nutr
49
31-41
2009
Homo sapiens
Urashima, T; Katayama, T; Sakanaka, M; Fukuda, K; Messer, M
Evolution of milk oligosaccharides: Origin and selectivity of the ratio of milk oligosaccharides to lactose among mammals.
Biochim Biophys Acta Gen Subj
130012
2021
Eutheria
Shah, N; Jelen, P
Lactose absorption by postweaning rats from yogurt, quarg, and quarg whey.
J Dairy Sci
74
1512-20
1991
Rattus
Gendrel, D; Richard-Lenoble, D; Dupont, C; Gendrel, C; Nardou, M; Chaussain, M
[Use of a fermented powdered milk in malnourished or lactose intolerant children]
Presse Med
19
700-4
1990
Bacteria
McDonough, FE; Hitchins, AD; Wong, NP; Wells, P; Bodwell, CE
Modification of sweet acidophilus milk to improve utilization by lactose-intolerant persons.
Am J Clin Nutr
45
570-4
1987
Homo sapiens
During, MJ; Xu, R; Young, D; Kaplitt, MG; Sherwin, RS; Leone, P
Peroral gene therapy of lactose intolerance using an adeno-associated virus vector.
Nat Med
4
1131-5
1998
Adeno-associated virus, Lamina, animal
de Vrese, M; Sieber, R; Stransky, M
[Lactose in human nutrition]
Schweiz Med Wochenschr
128
1393-400
1998
Homo sapiens
Ojetti, V; Gigante, G; Gabrielli, M; Ainora, ME; Mannocci, A; Lauritano, EC; Gasbarrini, G; Gasbarrini, A
The effect of oral supplementation with Lactobacillus reuteri or tilactase in lactose intolerant patients: randomized trial.
Eur Rev Med Pharmacol Sci
14
163-70
2010
Limosilactobacillus reuteri, Homo sapiens
Meraat, R; Issazadeh, K; Abdolahzadeh Ziabari, A; Faezi Ghasemi, M
Rapid Detection of Escherichia coli by ?-Galactosidase Biosensor Based on ZnO NPs and MWCNTs: A Comparative Study.
Curr Microbiol
77
2633-2641
2020
Escherichia coli
Büller, HA; Rings, EH; Montgomery, RK; Grand, RJ
Clinical aspects of lactose intolerance in children and adults.
Scand J Gastroenterol Suppl
188
73-80
1991
Homo sapiens
Cao, M; Che, L; Wang, J; Yang, M; Su, G; Fang, Z; Lin, Y; Xu, S; Wu, D
Effects of maternal over- and undernutrition on intestinal morphology, enzyme activity, and gene expression of nutrient transporters in newborn and weaned pigs.
Nutrition
30
1442-7
0
Suidae, Sus scrofa
Ameen, NA; Marino, C; Salas, PJ
cAMP-dependent exocytosis and vesicle traffic regulate CFTR and fluid transport in rat jejunum in vivo.
Am J Physiol Cell Physiol
284
C429-38
2003
Rattus
Han, J; Xu, Y; Yang, D; Yu, N; Bai, Z; Bian, L
Effect of Polysaccharides from Acanthopanax senticosus on Intestinal Mucosal Barrier of Escherichia coli Lipopolysaccharide Challenged Mice.
Asian-Australas J Anim Sci
29
134-41
2016
Mus sp.
Xu, Y; Wu, Q; Bai, L; Mu, G; Tuo, Y; Jiang, S; Zhu, X; Qian, F
Cloning, expression, and bioinformatics analysis and characterization of a ?-galactosidase from Bacillus coagulans T242.
J Dairy Sci
2021
Weizmannia coagulans, Escherichia coli BL21
Duvignaud, A; Lhomme, E; Pistone, T; Onaisi, R; Sitta, R; Journot, V; Nguyen, D; Peiffer-Smadja, N; Crémer, A; Bouchet, S; Darnaud, T; Poitrenaud, D; Piroth, L; Binquet, C; Michel, JF; Lefèvre, B; Lebeaux, D; Lebel, J; Dupouy, J; Roussillon, C; Gimbert, A; Wittkop, L; Thiébaut, R; Orne-Gliemann, J; Joseph, JP; Richert, L; Anglaret, X; Malvy, D; ,
Home Treatment of Older People with Symptomatic SARS-CoV-2 Infection (COVID-19): A structured Summary of a Study Protocol for a Multi-Arm Multi-Stage (MAMS) Randomized Trial to Evaluate the Efficacy and Tolerability of Several Experimental Treatments to Reduce the Risk of Hospitalisation or Death in outpatients aged 65 years or older (COVERAGE trial).
Trials
21
846
2020
Hepatitis B virus, Dialysis, Porphyria
Borinskaya, SA; Yankovsky, NK
[Combination of Genetic and Humanitarian (Cross-Cultural) Methods for the Identification of Human Genes Involved in the Process of Adaptation to Evolutionary New Environmental Factors].
Genetika
51
479-90
2015
animal, Homo sapiens, Filaria
Xu, S; Innes, DJ; Lynch, M; Cristescu, ME
The role of hybridization in the origin and spread of asexuality in Daphnia.
Mol Ecol
22
4549-61
2013
Daphnia pulicaria
Goodenough, ER; Kleyn, DH
Influence of viable yogurt microflora on digestion of lactose by the rat.
J Dairy Sci
59
601-6
1976
Metazoa
Adrian, J; Frangne, R
[Role of the digestive flora in adaptation to lactose consumption in rats]
Int J Vitam Nutr Res
48
170-6
1978
Rattus, Rattus norvegicus, Caecum, animal
Jumawan, J; Koldovský, O
Comparison of the effect of various doses of thyroxine on jejunal disaccharidases in intact and adrenalectomized rats during the first 3 weeks of life.
Enzyme
23
206-9
1978
Rattus
Leslie, J; MacLean, WC; Graham, GG
Effect of an episode of severe malnutrition and age on lactose absorption by recovered infants and children.
Am J Clin Nutr
32
971-4
1979
Homo sapiens
Barashneva, SM
[Clinical effectiveness of the therapeutic nutrition of sick children using enteral feeding preparations and low-lactose mixtures]
Vopr Pitan
60-4
0
Homo sapiens
Lojda, Z; Kociánová, J; Maratka, Z
Histochemistry of the human duodenal mucosa with special reference to the gradient of activities of the brush border enzymes.
Scand J Gastroenterol Suppl
54
7-13
1979
Homo sapiens
Fernandes, J; Vos, CE; Douwes, AC; Slotema, E; Degenhart, HJ
Respiratory hydrogen excretion as a parameter for lactose malabsorption in children.
Am J Clin Nutr
31
597-602
1978
Homo sapiens
Kim, KI; Benevenga, NJ; Grummer, RH
Estimation of the fraction of the lactose in a high lactose diet available for fermentation in the cecum and colon of the rat.
J Nutr
108
79-89
1978
Rattus
Paige, DM; Mellits, ED; Chiu, FY; Davis, L; Bayless, TM; Cordano, A
Blood glucose rise after lactose tolerance testing in infants.
Am J Clin Nutr
31
222-5
1978
Homo sapiens
Zieglauer, H; Höpfl-Kreiner, I
[The value of the "impression smear" in detecting giardia lamblia infection (author's transl)]
Padiatr Padol
13
165-73
1978
Homo sapiens
Roberts, MC
Carbohydrate digestion and absorption studies in the horse.
Res Vet Sci
18
64-9
1975
Equus caballus
Leichter, J; Tolensky, AF
Effect of dietary lactose on the absorption of protein, fat and calcium in the postweaning rat.
Am J Clin Nutr
28
238-41
1975
Rattus
Morin, CL; Roy, CC; Lasalle, R; Bonin, A
Small bowel mucosal dysfunction in patients with cystic fibrosis.
J Pediatr
88
213-6
1976
Homo sapiens
Lichtenberger, L; Welsh, JD; Johnson, LR
Relationship between the changes in gastrin levels and intestinal properties in the starved rat.
Am J Dig Dis
21
33-8
1976
Rattus
Solomons, NW; Castillo, C; Guerrero, AM
[Colonic fermentation in humans: effect of the ingestion of meat associated to milk]
Rev Med Chil
120
858-61
1992
Bos taurus
Tadesse, K; Leung, DT; Yuen, RC
The status of lactose absorption in Hong Kong Chinese children.
Acta Paediatr
81
598-600
1992
Homo sapiens
Gendrel, D; Richard-Lenoble, D; Kombila, M; Dupont, C; Moreno, JL; Gendrel, C; Nardou, M; Chaussain, M
Influence of intestinal parasitism on lactose absorption in well-nourished African children.
Am J Trop Med Hyg
46
137-40
1992
Homo sapiens, Ascaris
Brasseur, D; Goyens, P; Vis, HL
[Enzymes and histology of the intestinal mucosa of breast-fed African infants]
Ann Pediatr (Paris)
39
87-93
1992
Homo sapiens
Bel'mer, SV; Gasilina, TV; Zverkov, IV; Mukhina, IuG
[Disorders of humoral regulation of the digestive organ functions in children with malabsorption syndromes]
Pediatriia
35-8
1991
Homo sapiens
Shimizu, K; Harada, T; Okada, S
Toxicity of gentamicin in organ culture of fetal rat intestine.
Cell Biol Int Rep
15
479-84
1991
Rattus
Preedy, VR; Hammond, B; Iles, RA; Davies, SE; Gandy, JD; Chalmers, RA; Peters, TJ
Urinary excretion of nitrogenous and non-nitrogenous compounds in the chronic ethanol-fed rat.
Clin Sci (Lond)
80
393-400
1991
Rattus
Couet, C; Jan, P; Debry, G
Lactose and cataract in humans: a review.
J Am Coll Nutr
10
79-86
1991
Homo sapiens
Sinden, AA; Sutphen, JL
Dietary treatment of lactose intolerance in infants and children.
J Am Diet Assoc
91
1567-71
1991
Homo sapiens
Patanè, R; Sciacca, A; Bottaro, G; Mauro, L; Ciccia, M; Sciuto, C; Grigorio, R
[The clinical pictures of rotavirus infection in childhood. Studies on the admissions to the Clinica Pediatrica di Catania in 1984-1988]
Pediatr Med Chir
12
525-9
0
Homo sapiens
Heise, C; Dandekar, S; Kumar, P; Duplantier, R; Donovan, RM; Halsted, CH
Human immunodeficiency virus infection of enterocytes and mononuclear cells in human jejunal mucosa.
Gastroenterology
100
1521-7
1991
Homo sapiens
DiBattista, D
Lactose ingestion in the adult golden hamster (Mesocricetus auratus).
J Comp Psychol
105
95-102
1991
Mammalia
Boudraa, G; Touhami, M; Pochart, P; Soltana, R; Mary, JY; Desjeux, JF
Effect of feeding yogurt versus milk in children with persistent diarrhea.
J Pediatr Gastroenterol Nutr
11
509-12
1990
Homo sapiens
DiBattista, D
Conditioned taste avoidance induced by lactose ingestion in adult rats.
Physiol Behav
47
253-7
1990
Rattus
Rosado, JL; Morales, M; Pasquetti, A
Lactose digestion and clinical tolerance to milk, lactose-prehydrolyzed milk and enzyme-added milk: a study in undernourished continuously enteral-fed patients.
JPEN J Parenter Enteral Nutr
13
157-61
0
Homo sapiens
Ish-Horowicz, M; Korman, SH; Shapiro, M; Har-Even, U; Tamir, I; Strauss, N; Deckelbaum, RJ
Asymptomatic giardiasis in children.
Pediatr Infect Dis J
8
773-9
1989
Homo sapiens
Enck, P; Wienbeck, M
Repeated noninvasive measurement of gastrointestinal transit in rats.
Physiol Behav
46
633-7
1989
Bacteria
Griessen, M; Speich, PV; Infante, F; Bartholdi, P; Cochet, B; Donath, A; Courvoisier, B; Bonjour, JP
Effect of absorbable and nonabsorbable sugars on intestinal calcium absorption in humans.
Gastroenterology
96
769-75
1989
Homo sapiens
Ameen, VZ; Powell, GK
Quantitative fecal carbohydrate excretion in premature infants.
Am J Clin Nutr
49
1238-42
1989
Homo sapiens
Stryker, JA; Bartholomew, M
Failure of lactose-restricted diets to prevent radiation-induced diarrhea in patients undergoing whole pelvis irradiation.
Int J Radiat Oncol Biol Phys
12
789-92
1986
Homo sapiens
Cellesi, C; Rossolini, GM; Lusini, P; Gerli, R; Alessandrini, C
Enzyme activities and ultrastructure of intestinal epithelium in the mouse treated with chloramphenicol.
Boll Ist Sieroter Milan
65
552-6
1986
Mus sp.
Butzner, JD; Gall, DG
Effects of chronic protein-calorie malnutrition on small intestinal repair after an acute bacterial enteritis: a study in infant rabbits.
Pediatr Res
23
408-13
1988
Oryctolagus cuniculus
Collares, EF
[Adaptation of rats, after weaning, to a diet with a high concentration of lactose. I. Evaluation of water and diet ingestion]
Arq Gastroenterol
25
44-7
0
Rattus, Metazoa
Szylit, O; Dabard, J; Durand, M; Dumay, C; Bensaada, M; Raibaud, P
Production of volatile fatty acids as a result of bacterial interactions in the cecum of gnotobiotic rats and chickens fed a lactose-containing diet.
Reprod Nutr Dev
28
1455-64
1988
Gallus gallus, Rattus, Homo sapiens
Tzipori, S; Robins-Browne, RM; Gonis, G; Hayes, J; Withers, M; McCartney, E
Enteropathogenic Escherichia coli enteritis: evaluation of the gnotobiotic piglet as a model of human infection.
Gut
26
570-8
1985
Metazoa
Ferguson, A; Paul, G; Snodgrass, DR
Lactose tolerance in lambs with rotavirus diarrhoea.
Gut
22
114-9
1981
Ovis aries, Rotavirus, Areas
Newport, MJ; Turvey, A; Brooker, BE
Incidence of rotavirus in artificially reared pigs and some effects of diarrhoea on the physiology and histology of the gastrointestinal tract.
Res Vet Sci
32
48-51
1982
Suidae
Fiehring, C; Körting, HJ; Jung, G
[Rotavirus and malabsorption. Immunofluorescence microscopy studies of small intestine specimens]
Dtsch Z Verdau Stoffwechselkr
44
1-5
1984
Rotavirus
Tzipori, S; Smith, M; Halpin, C; Makin, T; Krautil, F
Intestinal changes associated with rotavirus and enterotoxigenic Escherichia coli infection in calves.
Vet Microbiol
8
35-43
1983
Rotavirus
Ratner, D; Shoshani, E; Dubnov, B
Milk protein-free diet for nonseasonal asthma and migraine in lactase-deficient patients.
Isr J Med Sci
19
806-9
1983
Homo sapiens, Indicator
Gilliland, SE; Kim, HS
Effect of viable starter culture bacteria in yogurt on lactose utilization in humans.
J Dairy Sci
67
1-6
1984
Bacteria
Ellestad-Sayed, JJ; Levitt, MD; Bond, JH
Milk intolerance in Manitoba Indian school children.
Am J Clin Nutr
33
2198-201
1980
Homo sapiens
Troncon, LE; Collares, EF; Oliveira, RB; Padovan, W; Meneghelli, UG
[Lactose malabsorption in adult patients at the Hospital das ClÃnicas de Ribeirão Preto]
Arq Gastroenterol
18
106-12
0
Homo sapiens
Kirschner, BS; DeFavaro, MV; Jensen, W
Lactose malabsorption in children and adolescents with inflammatory bowel disease.
Gastroenterology
81
829-32
1981
Homo sapiens, Saccharomyces cerevisiae
Uribe, M; Márquez, MA; GarcÃa-Ramos, G; Escobedo, V; Murillo, H; Guevara, L; Lisker, R
Treatment of chronic portal-systemic encephalopathy with lactose in lactase-deficient patients.
Dig Dis Sci
25
924-8
1980
Homo sapiens
Sabel, KG; Olegård, R; Mellander, M; Hildingsson, K
Interrelation between fatty acid oxidation and control of gluconeogenic substrates in small-for-gestational-age (SGA) infants with hypoglycemia and with normoglycemia.
Acta Paediatr Scand
71
53-61
1982
Homo sapiens
Barr, RG; Watkins, JB; Perman, JA
Mucosal function and breath hydrogen excretion: comparative studies in the clinical evaluation of children with nonspecific abdominal complaints.
Pediatrics
68
526-33
1981
Homo sapiens
Guo, W; Swaniker, F; Fonkalsrud, EW; Vo, K; Karamanoukian, R
Effect of intraamniotic dexamethasone administration on intestinal absorption in a rabbit gastroschisis model.
J Pediatr Surg
30
983-6; discussion 986-7
1995
Oryctolagus cuniculus, Homo sapiens
Ectors, NL; Geboes, KJ; De Vos, RM; Heidbuchel, HP; Rutgeerts, PJ; Desmet, VJ; Vantrappen, GR
Whipple's disease: a histological, immunocytochemical, and electron microscopic study of the small intestinal epithelium.
J Pathol
172
73-9
1994
Homo sapiens
Shu, D; Simpson, HV; Xu, RJ; Mellor, DJ; Reynolds, GW; Marshall, RB
Effects of Yersinia enterocolitica infection on growth of the body and internal organs in newborn colostrum-deprived piglets.
Biol Neonate
67
360-9
1995
Yersinia enterocolitica, Homo sapiens, Caecum
Evrard, S; Aprahamian, M; Hoeltzel, A; Vasilescu, M; Marescaux, J; Damgé, C
Trophic and enzymatic adaptation of the intestine to biliopancreatic bypass in the rat.
Int J Obes Relat Metab Disord
17
541-7
1993
Rattus, Metazoa
Guo, W; Gregg, JP; Fonkalsrud, EW
Effect of maternal ethanol intake on fetal rabbit gastrointestinal development.
J Pediatr Surg
29
1030-3; discussion 1033-4
1994
Indicator
Lindi, C; Marciani, P; Omodeo-Sale, F
Age related changes in functions and physicochemical properties of rat jejunal brush border membrane after chronic ethanol administration.
Comp Biochem Physiol C
104
263-8
1993
Rattus
Mahé, S; Marteau, P; Huneau, JF; Thuillier, F; Tomé, D
Intestinal nitrogen and electrolyte movements following fermented milk ingestion in man.
Br J Nutr
71
169-80
1994
Homo sapiens
Chesta, J; Antezana, C; AlegrÃa, S
[Lactulose fermentation and lactose absorption in Chilean patients with liver cirrhosis: importance for hepatic encephalopathy therapy]
Rev Med Chil
121
489-93
1993
Homo sapiens
Bottaro, G; Failla, P; Rotolo, N; Azzaro, F; Spina, M; Castiglione, N; Patané, R
[The predictive value of antigliadin antibodies (AGA) in the diagnosis of non-celiac gastrointestinal disease in children]
Minerva Pediatr
45
93-8
1993
Homo sapiens
Medow, MS; Glassman, MS; Schwarz, SM; Newman, LJ
Respiratory methane excretion in children with lactose intolerance.
Dig Dis Sci
38
328-32
1993
Homo sapiens
Desai, TK; Nathan, DF; Morin, MJ
Potentiation of butyrate-induced differentiation in human colon tumor cells by deoxycholate.
Cancer Lett
69
181-6
1993
Homo sapiens
Gaón, D; Doweck, Y; Gómez Zavaglia, A; Ruiz Holgado, A; Oliver, G
[Lactose digestion by milk fermented with Lactobacillus acidophilus and Lactobacillus casei of human origin]
Medicina (B Aires)
55
237-42
1995
Lactobacillus acidophilus, Lacticaseibacillus casei, Homo sapiens
King, TP; Begbie, R; Slater, D; McFadyen, M; Thom, A; Kelly, D
Sialylation of intestinal microvillar membranes in newborn, sucking and weaned pigs.
Glycobiology
5
525-34
1995
Suidae, Sus scrofa, Sambucus nigra, Metazoa, Maackia amurensis
Montes, RG; Bayless, TM; Saavedra, JM; Perman, JA
Effect of milks inoculated with Lactobacillus acidophilus or a yogurt starter culture in lactose-maldigesting children.
J Dairy Sci
78
1657-64
1995
Bacteria, Lactobacillus acidophilus, Homo sapiens, Streptococcus thermophilus, Lactobacillus delbrueckii subsp. lactis
Wéry, I; Deloyer, P; Dandrifosse, G
Effects of a single dose of orally-administered spermine on the intestinal development of unweaned rats.
Arch Physiol Biochem
104
163-72
1996
Rattus
Laroche, M; Bon, E; Moulinier, L; Cantagrel, A; Mazieres, B
Lactose intolerance and osteoporosis in men.
Rev Rhum Engl Ed
62
766-9
1995
Homo sapiens
Broom, DM; Goode, JA; Hall, SJ; Lloyd, DM; Parrott, RF
Hormonal and physiological effects of a 15 hour road journey in sheep: comparison with the responses to loading, handling and penning in the absence of transport.
Br Vet J
152
593-604
1996
animal
Cheng, CC; Etoh, J; Tanimura, T; Egashira, Y; Ohta, T; Sanada, H
Effects of dietary gluten on the hepatotoxic action of galactosamine and/or endotoxin in rats.
Biosci Biotechnol Biochem
60
439-43
1996
Rattus norvegicus
Kien, CL; McClead, RE; Cordero, L
In vivo lactose digestion in preterm infants.
Am J Clin Nutr
64
700-5
1996
Homo sapiens
Redel, CA; Shulman, RJ; Tivey, DR
Determinants of lactose digestion in the miniature pig.
Dig Dis Sci
42
137-44
1997
Sus scrofa, Homo sapiens
Northrop-Clewes, CA; Lunn, PG; Downes, RM
Lactose maldigestion in breast-feeding Gambian infants.
J Pediatr Gastroenterol Nutr
24
257-63
1997
Homo sapiens
Corazza, GR; Ginaldi, L; Furia, N; Marani-Toro, G; Di Giammartino, D; Quaglino, D
The impact of HIV infection on lactose absorptive capacity.
J Infect
35
31-5
1997
Human immunodeficiency virus 1, Homo sapiens
Oesterreicher, TJ; Leeper, LL; Finegold, MJ; Darlington, GJ; Henning, SJ
Intestinal maturation in mice lacking CCAAT/enhancer-binding protein alpha (C/EPBalpha).
Biochem J
330 ( Pt 3)
1165-71
1998
Metazoa
Gómez-de-Segura, IA; Prieto, I; Grande, AG; GarcÃa, P; Guerra, A; Mendez, J; De Miguel, E
Growth hormone reduces mortality and bacterial translocation in irradiated rats.
Acta Oncol
37
179-85
1998
Rattus
Mizuno, N; Takagi, C; Yamamoto, N; Takahashi, K
Effect of cyclosporine A on the gastrointestinal absorption of acyclovir in neonatal and adult rats.
Biol Neonate
74
243-52
1998
Rattus
Burrin, DG; Fiorotto, ML; Hadsell, DL
Transgenic hypersecretion of des(1-3) human insulin-like growth factor I in mouse milk has limited effects on the gastrointestinal tract in suckling pups.
J Nutr
129
51-6
1999
Homo sapiens, Mus musculus, Mus sp.
Weese, JS; Parsons, DA; Staempfli, HR
Association of Clostridium difficile with enterocolitis and lactose intolerance in a foal.
J Am Vet Med Assoc
214
229-32, 205
1999
Clostridioides difficile, Rotavirus
Meloni, GF; Colombo, C; La Vecchia, C; Ruggiu, G; Mannazzu, MC; Ambrosini, G; Cherchi, PL
Lactose absorption in patients with ovarian cancer.
Am J Epidemiol
150
183-6
1999
Homo sapiens
Kinouchi, T; Koizumi, K; Kuwata, T; Yajima, T
Evaluation of the development of intestinal function in rats reared on hydrolyzed or native protein-based milk formula.
J Pediatr Gastroenterol Nutr
29
155-62
1999
Rattus
Heyman, M
Effect of lactic acid bacteria on diarrheal diseases.
J Am Coll Nutr
19
137S-146S
2000
Bacteria, Homo sapiens, animal
Meloni, GF; Colombo, C; La Vecchia, C; Pacifico, A; Tomasi, P; Ogana, A; Marinaro, AM; Meloni, T
High prevalence of lactose absorbers in Northern Sardinian patients with type 1 and type 2 diabetes mellitus.
Am J Clin Nutr
73
582-5
2001
Homo sapiens, Rattus
Kwok, T; Woo, J; Kwan, M
Does low lactose milk powder improve the nutritional intake and nutritional status of frail older Chinese people living in nursing homes?
J Nutr Health Aging
5
17-21
2001
Homo sapiens
Kamilova, AT; Akhmedov, NN; Pulatova, DB; Nurmatov, BA
[Intestinal microbiocenosis in children with intestinal enzymopathy]
Zh Mikrobiol Epidemiol Immunobiol
97-9
0
Homo sapiens, Escherichia coli, Bacteria, Enterobacteriaceae, Proteus
Thong-Ngam, D; Suwangool, P; Prempracha, J; Tangkijvanich, P; Vivatvekin, B; Sriratanabun, A
Lactose intolerance and intestinal villi morphology in Thai people.
J Med Assoc Thai
84
1090-6
2001
Homo sapiens
Suarez, FL; Zumarraga, LM; Furne, JK; Levitt, MD
Nutritional supplements used in weight-reduction programs increase intestinal gas in persons who malabsorb lactose.
J Am Diet Assoc
101
1447-52
2001
Homo sapiens
Oliver, WT; Mathews, SA; Phillips, O; Jones, EE; Odle, J; Harrell, RJ
Efficacy of partially hydrolyzed corn syrup solids as a replacement for lactose in manufactured liquid diets for neonatal pigs.
J Anim Sci
80
143-53
2002
Suidae, Zea mays subsp. mays
Hunt, E; Fu, Q; Armstrong, MU; Rennix, DK; Webster, DW; Galanko, JA; Chen, W; Weaver, EM; Argenzio, RA; Rhoads, JM
Oral bovine serum concentrate improves cryptosporidial enteritis in calves.
Pediatr Res
51
370-6
2002
Bos taurus, Cryptosporidium, Cryptosporidium parvum, Homo sapiens, Metazoa
Shulman, RJ
Effect of enteral administration of insulin on intestinal development and feeding tolerance in preterm infants: a pilot study.
Arch Dis Child Fetal Neonatal Ed
86
F131-3
2002
Homo sapiens
Kwinta, P; Mitkowska, Z; Kruczek, P; Tomasik, T; Pietrzyk, JJ
[Influence of the lactose free and lactose containing diet on prevalence of gram-negative sepsis and feeding intolerance in very low birth weight infants: double-blind randomized trial]
Przegl Lek
59 Suppl 1
63-6
2002
Homo sapiens
Sangild, PT; Petersen, YM; Schmidt, M; Elnif, J; Petersen, TK; Buddington, RK; Greisen, G; Michaelsen, KF; Burrin, DG
Preterm birth affects the intestinal response to parenteral and enteral nutrition in newborn pigs.
J Nutr
132
2673-81
2002
Suidae
Fenton, TR; Belik, J
Routine handling of milk fed to preterm infants can significantly increase osmolality.
J Pediatr Gastroenterol Nutr
35
298-302
2002
Homo sapiens
Erasmus, HD; Ludwig-Auser, HM; Paterson, PG; Sun, D; Sankaran, K
Enhanced weight gain in preterm infants receiving lactase-treated feeds: a randomized, double-blind, controlled trial.
J Pediatr
141
532-7
2002
Homo sapiens
Gartner, H; Graul, MC; Oesterreicher, TJ; Finegold, MJ; Henning, SJ
Development of the fetal intestine in mice lacking the glucocorticoid receptor (GR).
J Cell Physiol
194
80-7
2003
Mus sp.
Sangild, PT; Petersen, YM; Schmidt, M; Elnif, J; Petersen, TK; Buddington, RK; Greisen, G; Michaelsen, KF; Burrin, DG
Preterm birth affects the intestinal response to parenteral and enteral nutrition in newborn pigs.
J Nutr
132
3786-94
2002
Suidae
Motouri, M; Matsuyama, H; Yamamura, J; Tanaka, M; Aoe, S; Iwanaga, T; Kawakami, H
Milk sphingomyelin accelerates enzymatic and morphological maturation of the intestine in artificially reared rats.
J Pediatr Gastroenterol Nutr
36
241-7
2003
Rattus, Homo sapiens, Rattus norvegicus
Limbach, A; Hoepffner, W; Tannapfel, A; Müller, DM; Mothes, T; Richter, T
[Long-term study of patients with coeliac disease in childhood and adolescence: latent and transient coeliac disease]
Klin Padiatr
215
76-81
0
Homo sapiens
Yang, Y; He, M; Cui, H; Bian, L
[Study on the incidence of lactose intolerance of children in China]
Wei Sheng Yan Jiu
28
44-6
1999
Homo sapiens
Correa-Matos, NJ; Donovan, SM; Isaacson, RE; Gaskins, HR; White, BA; Tappenden, KA
Fermentable fiber reduces recovery time and improves intestinal function in piglets following Salmonella typhimurium infection.
J Nutr
133
1845-52
2003
Homo sapiens, Salmonella enterica subsp. enterica serovar Typhimurium
Klimov, LIa
[Lactose tolerance in children with chronic gastroduodenal zone diseases]
Eksp Klin Gastroenterol
99-104, 120
2003
Homo sapiens
Zhong, Y; Priebe, MG; Vonk, RJ; Huang, CY; Antoine, JM; He, T; Harmsen, HJ; Welling, GW
The role of colonic microbiota in lactose intolerance.
Dig Dis Sci
49
78-83
2004
Homo sapiens
Escoboza, PM; Fernandes, MI; Peres, LC; Einerhand, AW; Galvão, LC
Adult-type Hypolactasia: Clinical, Morphologic and Functional Characteristics in Brazilian Patients at a University Hospital.
J Pediatr Gastroenterol Nutr
39
361-365
2004
Homo sapiens
Boyer, J; Brown, D; Liu, RH
Uptake of quercetin and quercetin 3-glucoside from whole onion and apple peel extracts by Caco-2 cell monolayers.
J Agric Food Chem
52
7172-9
2004
Malus domestica, Allium cepa
Enattah, N; Pekkarinen, T; Välimäki, MJ; Löyttyniemi, E; Järvelä, I
Genetically defined adult-type hypolactasia and self-reported lactose intolerance as risk factors of osteoporosis in Finnish postmenopausal women.
Eur J Clin Nutr
59
1105-11
2005
Homo sapiens
Deloyer, P; Peulen, O; Dandrifosse, G
Intestinal effects of long-lasting spermine ingestion by suckling rats.
Exp Physiol
90
901-8
2005
Rattus
He, W; Huang, CY
[Cloning and preparation of cDNA probe from BAlb/c mice]
Sichuan Da Xue Xue Bao Yi Xue Ban
36
808-11
2005
Mus sp.
Stoll, B; Price, PT; Reeds, PJ; Chang, X; Henry, JF; van Goudoever, JB; Holst, JJ; Burrin, DG
Feeding an elemental diet vs a milk-based formula does not decrease intestinal mucosal growth in infant pigs.
JPEN J Parenter Enteral Nutr
30
32-9
0
Suidae, Homo sapiens
Rasinpera, H; Saarinen, K; Pelkonen, A; Jarvela, I; Savilahti, E; Kolho, KL
Molecularly defined adult-type hypolactasia in school-aged children with a previous history of cow's milk allergy.
World J Gastroenterol
12
2264-8
2006
Homo sapiens
Tinmouth, J; Kandel, G; Tomlinson, G; Walmsley, S; Steinhart, AH; Glazier, R
The effect of dairy product ingestion on human immunodeficiency virus-related diarrhea in a sample of predominantly gay men: a randomized, controlled, double-blind, crossover trial.
Arch Intern Med
166
1178-83
2006
Homo sapiens
Heyman, MB; ,
Lactose intolerance in infants, children, and adolescents.
Pediatrics
118
1279-86
2006
Homo sapiens
Harris, EE; Meyer, D
The molecular signature of selection underlying human adaptations.
Am J Phys Anthropol
Suppl 43
89-130
2006
Homo sapiens
Anthoni, SR; Rasinperä, HA; Kotamies, AJ; Komu, HA; Pihlajamäki, HK; Kolho, KL; Järvelä, IE
Molecularly defined adult-type hypolactasia among working age people with reference to milk consumption and gastrointestinal symptoms.
World J Gastroenterol
13
1230-5
2007
Homo sapiens
Corl, BA; Harrell, RJ; Moon, HK; Phillips, O; Weaver, EM; Campbell, JM; Arthington, JD; Odle, J
Effect of animal plasma proteins on intestinal damage and recovery of neonatal pigs infected with rotavirus.
J Nutr Biochem
18
778-84
2007
Suidae
Ojetti, V; Gabrielli, M; Migneco, A; Lauritano, C; Zocco, MA; Scarpellini, E; Nista, EC; Gasbarrini, G; Gasbarrini, A
Regression of lactose malabsorption in coeliac patients after receiving a gluten-free diet.
Scand J Gastroenterol
1-4
2007
Homo sapiens
Roy, K; Anba, J; Corthier, G; Rigottier-Gois, L; Monnet, V; Mistou, MY
Metabolic Adaptation of Lactococcus lactis in the Digestive Tract: The Example of Response to Lactose.
J Mol Microbiol Biotechnol
14
137-44
2008
Mus musculus
Siggers, RH; Thymann, T; Jensen, BB; Mølbak, L; Heegaard, PM; Schmidt, M; Buddington, RK; Sangild, PT
Elective cesarean delivery affects gut maturation and delays microbial colonization but does not increase necrotizing enterocolitis in preterm pigs.
Am J Physiol Regul Integr Comp Physiol
294
R929-38
2008
Suidae
Enattah, NS; Jensen, TG; Nielsen, M; Lewinski, R; Kuokkanen, M; Rasinpera, H; El-Shanti, H; Seo, JK; Alifrangis, M; Khalil, IF; Natah, A; Ali, A; Natah, S; Comas, D; Mehdi, SQ; Groop, L; Vestergaard, EM; Imtiaz, F; Rashed, MS; Meyer, B; Troelsen, J; Peltonen, L
Independent introduction of two lactase-persistence alleles into human populations reflects different history of adaptation to milk culture.
Am J Hum Genet
82
57-72
2008
Bos taurus, Camelus bactrianus, Homo sapiens
Mendoza, E; Crismatt, C; Matos, R; Sabagh, O; Campo, M; Cepeda, J; Villanueva, D
[Diagnosis of small intestinal bacterial overgrowth in children: the use of lactulose in the breath hydrogen test as a screening test]
Biomedica
27
325-32
2007
Homo sapiens
Lukovac, S; Los, EL; Stellaard, F; Rings, EH; Verkade, HJ
Essential fatty acid deficiency in mice impairs lactose digestion.
Am J Physiol Gastrointest Liver Physiol
295
G605-13
2008
Mus sp.
Tooley, KL; Howarth, GS; Butler, RN; Lymn, KA; Penttila, IA
The Effects of Formula Feeding on Physiological and Immunological Parameters in the Gut of Neonatal Rats.
Dig Dis Sci
2008
Metazoa, Rattus, Homo sapiens, Cannula
Sadykov, BA; Kuchkarova, LS; Ermatova, SU; Ergashev, NA
[Activity of digestive enzymes in offspring of rats fed a ration contaminated by heavy metals during lactation]
Vopr Pitan
78
47-50
2009
Rattus
Caroli, AM; Chessa, S; Erhardt, GJ
Invited review: milk protein polymorphisms in cattle: effect on animal breeding and human nutrition.
J Dairy Sci
92
5335-52
2009
Homo sapiens, Bos taurus
Shulman, RJ; Ou, CN; Smith, EO
Evaluation of Potential Factors Predicting Attainment of Full Gavage Feedings in Preterm Infants.
Neonatology
99
38-44
2010
Homo sapiens, Groundnut rosette virus
Vandenplas, Y; De Greef, E; Devreker, T; Hauser, B
Soy infant formula: is it that bad?
Acta Paediatr
2010
Homo sapiens, Bos taurus, Metazoa
Fijlstra, M; Rings, EH; Verkade, HJ; van Dijk, TH; Kamps, WA; Tissing, WJ
Lactose maldigestion during methotrexate-induced gastrointestinal mucositis in a rat model.
Am J Physiol Gastrointest Liver Physiol
300
G283-91
2011
Rattus, Homo sapiens, Rattus norvegicus
Haberkorn, BC; Ermens, AA; Koeken, A; Cobbaert, CM; van Guldener, C
Improving diagnosis of adult-type hypolactasia in patients with abdominal complaints.
Clin Chem Lab Med
2011
Homo sapiens
Mielcarek, C; Romond, PC; Romond, MB; Bezirtzoglou, E
Modulation of bacterial translocation in mice mediated through lactose and human milk oligosaccharides.
Anaerobe
17
361-6
2011
Mus sp.
Pereira-Rodríguez, A; Fernández-Leiro, R; González-Siso, MI; Cerdán, ME; Becerra, M; Sanz-Aparicio, J
Structural basis of specificity in tetrameric Kluyveromyces lactis ?-galactosidase.
J Struct Biol
177
392-401
2012
Kluyveromyces lactis, Saccharomyces cerevisiae
Almeida, CC; Lorena, SL; Pavan, CR; Akasaka, HM; Mesquita, MA
Beneficial Effects of Long-Term Consumption of a Probiotic Combination of Lactobacillus casei Shirota and Bifidobacterium breve Yakult May Persist After Suspension of Therapy in Lactose-Intolerant Patients.
Nutr Clin Pract
2012
Homo sapiens
M?dry, E; Krasi?ska, B; Drzyma?a-Czy?, S; Sands, D; Lisowska, A; Grebowiec, P; Minarowska, A; Oralewska, B; Ma?kowski, P; Moczko, J; Walkowiak, J
Lactose malabsorption is a risk factor for decreased bone mineral density in pancreatic insufficient cystic fibrosis patients.
Eur J Hum Genet
2012
Homo sapiens
Yang, J; Deng, Y; Chu, H; Cong, Y; Zhao, J; Pohl, D; Misselwitz, B; Fried, M; Dai, N; Fox, M
Prevalence and presentation of lactose intolerance and effects on dairy product intake in healthy subjects and patients with irritable bowel syndrome.
Clin Gastroenterol Hepatol
11
262-268.e1
2013
Homo sapiens
Sudun, ; Wulijideligen, ; Arakawa, K; Miyamoto, M; Miyamoto, T
Interaction between lactic acid bacteria and yeasts in airag, an alcoholic fermented milk.
Anim Sci J
84
66-74
2013
Bacteria, Kluyveromyces marxianus, Lactobacillus helveticus, Leuconostoc mesenteroides, Limosilactobacillus reuteri, Saccharomyces cerevisiae, yeasts
Alexandre, V; Even, PC; Larue-Achagiotis, C; Blouin, JM; Blachier, F; Benamouzig, R; Tomé, D; Davila, AM
Lactose malabsorption and colonic fermentations alter host metabolism in rats.
Br J Nutr
1-7
2013
Rattus, Microbiota, Caecum
Jiang, P; Wan, JM; Cilieborg, MS; Sit, WH; Sangild, PT
Premature Delivery Reduces Intestinal Cytoskeleton, Metabolism and Stress Response Proteins in Newborn Formula-Fed Pigs.
J Pediatr Gastroenterol Nutr
2013
Suidae
Shcherbakova, PL; Parfenov, AI; Ruchkina, IN; Fadeeva, NA; Gubina, AV; Melik-Agadzhanian, NB; Poleva, NI; Khomeriki, SG; Chikunova, BZ
[Lactase deficiency in patients with postinfectious irritable bowel syndrome and the role of intestinal microflora in its development].
Eksp Klin Gastroenterol
91-8
2012
Homo sapiens
Jurgo?ski, A; Ju?kiewicz, J; Zdu?czyk, Z
An anthocyanin-rich extract from Kamchatka honeysuckle increases enzymatic activity within the gut and ameliorates abnormal lipid and glucose metabolism in rats.
Nutrition
2013
Rattus, Lonicera, Rattus norvegicus, Metazoa, Lonicera caerulea, Caerulea
Marozik, P; Mosse, I; Alekna, V; Rudenko, E; Tamulaitien?, M; Ramanau, H; Strazdien?, V; Samokhovec, V; Ameliyanovich, M; Byshnev, N; Gonchar, A; Kundas, L
Association Between Polymorphisms of VDR, COL1A1, and LCT Genes and Bone Mineral Density in Belarusian Women With Severe Postmenopausal Osteoporosis.
Medicina (Kaunas)
49
177-84
2013
Homo sapiens
Li, Y; Jensen, ML; Chatterton, DE; Jensen, BB; Thymann, T; Kvistgaard, AS; Sangild, PT
Raw bovine milk improves gut responses to feeding relative to infant formula in preterm piglets.
Am J Physiol Gastrointest Liver Physiol
306
G81-90
2014
Homo sapiens, Bos taurus, Suidae, Sus scrofa
MacGillivray, S; Fahey, T; McGuire, W
Lactose avoidance for young children with acute diarrhoea.
Cochrane Database Syst Rev
10
CD005433
2013
Homo sapiens
Gerbault, P; Roffet-Salque, M; Evershed, RP; Thomas, MG
How long have adult humans been consuming milk?
IUBMB Life
65
983-90
2013
Homo sapiens, Mammalia
Perets, TT; Shporn, E; Aizic, S; Kelner, E; Levy, S; Bareli, Y; Pakanaev, L; Niv, Y; Dickman, R
A Diagnostic Approach to Patients with Suspected Lactose Malabsorption.
Dig Dis Sci
2013
Homo sapiens
Rune, I; Hansen, CH; Ellekilde, M; Nielsen, DS; Skovgaard, K; Rolin, BC; Lykkesfeldt, J; Josefsen, K; Tranberg, B; Kihl, P; Hansen, AK
Ampicillin-improved glucose tolerance in diet-induced obese C57BL/6NTac mice is age dependent.
J Diabetes Res
2013
319321
2013
Mus sp.
Zhao, Q; Liu, F; Hou, Z; Yuan, C; Zhu, X
High Level Production of ?-Galactosidase Exhibiting Excellent Milk-Lactose Degradation Ability from Aspergillus oryzae by Codon and Fermentation Optimization.
Appl Biochem Biotechnol
172
2787-99
2014
Aspergillus oryzae
Jeong, C; Di Rienzo, A
Adaptations to local environments in modern human populations.
Curr Opin Genet Dev
29
1-8
2014
Homo sapiens
Karakachoff, M; Duforet-Frebourg, N; Simonet, F; Le Scouarnec, S; Pellen, N; Lecointe, S; Charpentier, E; Gros, F; Cauchi, S; Froguel, P; Copin, N; , ; Le Tourneau, T; Probst, V; Le Marec, H; Molinaro, S; Balkau, B; Redon, R; Schott, JJ; Blum, MG; Dina, C; ,
Fine-scale human genetic structure in Western France.
Eur J Hum Genet
23
831-6
2015
Homo sapiens
Lachance, J; Tishkoff, SA
Population Genomics of Human Adaptation.
Annu Rev Ecol Evol Syst
44
123-143
2013
Homo sapiens
Warinner, C; Hendy, J; Speller, C; Cappellini, E; Fischer, R; Trachsel, C; Arneborg, J; Lynnerup, N; Craig, OE; Swallow, DM; Fotakis, A; Christensen, RJ; Olsen, JV; Liebert, A; Montalva, N; Fiddyment, S; Charlton, S; Mackie, M; Canci, A; Bouwman, A; Rühli, F; Gilbert, MT; Collins, MJ
Direct evidence of milk consumption from ancient human dental calculus.
Sci Rep
4
7104
2014
Homo sapiens
Zheng, X; Chu, H; Cong, Y; Deng, Y; Long, Y; Zhu, Y; Pohl, D; Fried, M; Dai, N; Fox, M
Self-reported lactose intolerance in clinic patients with functional gastrointestinal symptoms: prevalence, risk factors, and impact on food choices.
Neurogastroenterol Motil
27
1138-46
2015
Homo sapiens
Yang, JF; Fox, M; Chu, H; Zheng, X; Long, YQ; Pohl, D; Fried, M; Dai, N
Four-sample lactose hydrogen breath test for diagnosis of lactose malabsorption in irritable bowel syndrome patients with diarrhea.
World J Gastroenterol
21
7563-70
2015
Homo sapiens
Pepoian, AZ; Arutunian, N; Grigorian, A; Tsaturian, VV; Manvelian, AM; Dilnian, E; Balaian, MA; Torok, T
[THE CERTAIN CLINICAL CHARACTERISTICS OF BLOOD IN PATIENTS WITH FAMILY MEDITERRANEAN FEVER OF ARMENIAN POPULATION].
Klin Lab Diagn
60
46-7
2015
Homo sapiens
Grenov, B; Briend, A; Sangild, PT; Thymann, T; Rytter, MH; Hother, AL; Mølgaard, C; Michaelsen, KF
Undernourished Children and Milk Lactose.
Food Nutr Bull
37
85-99
2016
Homo sapiens, Microbiota, Mammalia
Pieper, R; Scharek-Tedin, L; Zetzsche, A; Röhe, I; Kröger, S; Vahjen, W; Zentek, J
Bovine milk-based formula leads to early maturation-like morphological, immunological, and functional changes in the jejunum of neonatal piglets.
J Anim Sci
94
989-99
2016
Suidae
Marasz, A
[Frequency and clinical overview of hypolactasia among children, adolescents and students of Szczecin schools].
Pomeranian J Life Sci
61
207-13
2015
Homo sapiens
Goodrich, JK; Davenport, ER; Beaumont, M; Jackson, MA; Knight, R; Ober, C; Spector, TD; Bell, JT; Clark, AG; Ley, RE
Genetic Determinants of the Gut Microbiome in UK Twins.
Cell Host Microbe
19
731-43
2016
Bacteria, Bifidobacterium
Field, Y; Boyle, EA; Telis, N; Gao, Z; Gaulton, KJ; Golan, D; Yengo, L; Rocheleau, G; Froguel, P; McCarthy, MI; Pritchard, JK
Detection of human adaptation during the past 2000 years.
Science
354
760-764
2016
Pseudomugilidae, Homo sapiens
Metzler-Zebeli, BU; Lawlor, PG; Magowan, E; McCormack, UM; Curião, T; Hollmann, M; Ertl, R; Aschenbach, JR; Zebeli, Q
Finishing pigs that are divergent in feed efficiency show small differences in intestinal functionality and structure.
PLoS One
12
e0174917
2017
Suidae
Wark, AR; Terman, EJ; Tabin, CJ
miR-128-1 is not required for hair pigmentation in mice.
Exp Dermatol
2017
Homo sapiens
Teramura, H; Sota, K; Iwasaki, M; Ogihara, H
Comparison of the quantitative dry culture methods with both conventional media and most probable number method for the enumeration of coliforms and Escherichia coli/coliforms in food.
Lett Appl Microbiol
65
57-65
2017
Escherichia, Bacteria
Yao, S; Hong, CC; Bandera, EV; Zhu, Q; Liu, S; Cheng, TD; Zirpoli, G; Haddad, SA; Lunetta, KL; Ruiz-Narvaez, EA; McCann, SE; Troester, MA; Rosenberg, L; Palmer, JR; Olshan, AF; Ambrosone, CB
Demographic, lifestyle, and genetic determinants of circulating concentrations of 25-hydroxyvitamin D and vitamin D-binding protein in African American and European American women.
Am J Clin Nutr
105
1362-1371
2017
Homo sapiens
Sissolak, G; Seftel, M; Uldrick, TS; Esterhuizen, TM; Mohamed, N; Kotze, D
Burkitt's Lymphoma and B-Cell Lymphoma Unclassifiable With Features Intermediate Between Diffuse Large B-Cell Lymphoma and Burkitt's Lymphoma in Patients With HIV: Outcomes in a South African Public Hospital.
J Glob Oncol
3
218-226
2017
Homo sapiens
Goodrich, JK; Davenport, ER; Clark, AG; Ley, RE
The Relationship Between the Human Genome and Microbiome Comes into View.
Annu Rev Genet
2017
Homo sapiens, Bacteria
Kryuchko, TO; Nesina, IM; Tkachenko, OY
Diagnostic algorithm and peculiarities of monitoring for infants with disorders of the gastrointestinal tract.
Wiad Lek
70
275-281
2017
Homo sapiens
Pimentel, G; Burton, KJ; Rosikiewicz, M; Freiburghaus, C; von Ah, U; Münger, LH; Pralong, FP; Vionnet, N; Greub, G; Badertscher, R; Vergères, G
Blood lactose after dairy product intake in healthy men.
Br J Nutr
118
1070-1077
2017
Microbiota
Heine, RG; AlRefaee, F; Bachina, P; De Leon, JC; Geng, L; Gong, S; Madrazo, JA; Ngamphaiboon, J; Ong, C; Rogacion, JM
Lactose intolerance and gastrointestinal cow's milk allergy in infants and children - common misconceptions revisited.
World Allergy Organ J
10
41
2017
Homo sapiens
Sun, J; Li, Y; Nguyen, DN; Mortensen, MS; van den Akker, CHP; Skeath, T; Pors, SE; Pankratova, S; Rudloff, S; Sørensen, SJ; Burrin, DG; Thymann, T; Sangild, PT
Nutrient Fortification of Human Donor Milk Affects Intestinal Function and Protein Metabolism in Preterm Pigs.
J Nutr
148
336-347
2018
Suidae
Neuvonen, MI; Korpela, K; Kyrklund, K; Rintala, RJ; Pakarinen, MP
Intestinal Microbiota in Hirschsprung Disease.
J Pediatr Gastroenterol Nutr
2018
Homo sapiens
Baldan, A; Tagliati, S; Saccomandi, D; Brusaferro, A; Busoli, L; Scala, A; Malaventura, C; Maggiore, G; Borgna-Pignatti, C
Assessment of Lactose-Free Diet on the Phalangeal Bone Mineral Status in Italian Adolescents Affected by Adult-Type Hypolactasia.
Nutrients
10
2018
Homo sapiens
Sun, J; Li, Y; Pan, X; Nguyen, DN; Brunse, A; Bojesen, AM; Rudloff, S; Mortensen, MS; Burrin, DG; Sangild, PT
Human Milk Fortification with Bovine Colostrum Is Superior to Formula-Based Fortifiers to Prevent Gut Dysfunction, Necrotizing Enterocolitis, and Systemic Infection in Preterm Pigs.
JPEN J Parenter Enteral Nutr
2018
Bacteria, Staphylococcus, Enterococcus, Microbiota
Su, X; Wang, S; Su, G; Zheng, Z; Zhang, J; Ma, Y; Liu, Z; Zhou, H; Zhang, Y; Zhang, L
Production of microhomologous-mediated site-specific integrated LacS gene cow using TALENs.
Theriogenology
119
282-288
2018
Saccharolobus solfataricus, archaeon
Ren, S; Hui, Y; Obelitz-Ryom, K; Brandt, AB; Kot, W; Nielsen, DS; Thymann, T; Sangild, PT; Nguyen, DN
Neonatal gut and immune maturation is determined more by postnatal age than by post-conceptional age in moderately preterm pigs.
Am J Physiol Gastrointest Liver Physiol
2018
Suidae
Zhou, S; Hang, Y; Wang, J; Fang, R
Enzyme activity and phosphate uptake in the small intestine of Sprague Dawley rats improved by supplementation of infant formula with prebiotics.
Anim Nutr
4
300-304
2018
Rattus
Vitellio, P; Celano, G; Bonfrate, L; Gobbetti, M; Portincasa, P; De Angelis, M
Effects of Bifidobacterium longum and Lactobacillus rhamnosus on Gut Microbiota in Patients with Lactose Intolerance and Persisting Functional Gastrointestinal Symptoms: A Randomised, Double-Blind, Cross-Over Study.
Nutrients
11
2019
Homo sapiens
Walkowiak, J; Fidler-Wito?, E; Glapa, A; Paszkowski, J; Borejsza-Wysocki, M; Mi?kiewicz-Chotnicka, A; Banasiewicz, T; Lisowska, A
Lactose intolerance, lactose malabsorption and genetic predisposition to adult-type hypolactasia in patients after restorative proctocolectomy.
Acta Biochim Pol
66
173-175
2019
Homo sapiens
Xin, Y; Guo, T; Zhang, Y; Wu, J; Kong, J
A new ?-galactosidase extracted from the infant feces with high hydrolytic and transgalactosylation activity.
Appl Microbiol Biotechnol
2019
Homo sapiens
Apata, M; Pfeifer, SP
Recent population genomic insights into the genetic basis of arsenic tolerance in humans: the difficulties of identifying positively selected loci in strongly bottlenecked populations.
Heredity (Edinb)
124
253-262
2020
Homo sapiens
Liu, S; Rezende, RM; Moreira, TG; Tankou, SK; Cox, LM; Wu, M; Song, A; Dhang, FH; Wei, Z; Costamagna, G; Weiner, HL
Oral Administration of miR-30d from Feces of MS Patients Suppresses MS-like Symptoms in Mice by Expanding Akkermansia muciniphila.
Cell Host Microbe
26
779-794.e8
2019
Akkermansia muciniphila, Akkermansia
Seoane, RG; Garcia-Recio, V; Garrosa, M; Rojo, MÁ; Jiménez, P; Girbés, T; Cordoba-Diaz, M; Cordoba-Diaz, D
Human health effects of lactose consumption as food and drug ingredient.
Curr Pharm Des
2020
Homo sapiens
García, IG; Rodriguez-Rubio, M; Mariblanca, AR; de Soto, LM; García, LD; Villatoro, JM; Parada, JQ; Meseguer, ES; Rosales, MJ; González, J; Arribas, JR; Carcas, AJ; de la Oliva, P; Borobia, AM
A randomized multicenter clinical trial to evaluate the efficacy of melatonin in the prophylaxis of SARS-CoV-2 infection in high-risk contacts (MeCOVID Trial): A structured summary of a study protocol for a randomised controlled trial.
Trials
21
466
2020
Human immunodeficiency virus 1
Devaux, CA; Million, M; Raoult, D
The Butyrogenic and Lactic Bacteria of the Gut Microbiota Determine the Outcome of Allogenic Hematopoietic Cell Transplant.
Front Microbiol
11
1642
2020
Bacteria
Couce, ML; Sánchez-Pintos, P; González-Vioque, E; Leis, R
Clinical Utility of LCT Genotyping in Children with Suspected Functional Gastrointestinal Disorder.
Nutrients
12
2020
Homo sapiens
Diao, H; Jiao, A; Yu, B; He, J; Zheng, P; Yu, J; Luo, Y; Luo, J; Mao, X; Chen, D
Beet Pulp: An Alternative to Improve the Gut Health of Growing Pigs.
Animals (Basel)
10
2020
Beta vulgaris
Krieger-Grübel, C; Hutter, S; Hiestand, M; Brenner, I; Güsewell, S; Borovicka, J
Treatment efficacy of a low FODMAP diet compared to a low lactose diet in IBS patients: A randomized, cross-over designed study.
Clin Nutr ESPEN
40
83-89
2020
Homo sapiens
Yamamoto, E; Watanabe, R; Ichimura, T; Ishida, T; Kimura, K
Effect of lactose hydrolysis on the milk-fermenting properties of Lactobacillus delbrueckii ssp. bulgaricus 2038 and Streptococcus thermophilus 1131.
J Dairy Sci
104
1454-1464
2021
Streptococcus thermophilus, Lactobacillus delbrueckii
Ratajczak, AE; Rychter, AM; Zawada, A; Dobrowolska, A; Krela-Ka?mierczak, I
Lactose intolerance in patients with inflammatory bowel diseases and dietary management in prevention of osteoporosis.
Nutrition
82
111043
2021
Homo sapiens
Zhao, J; Zhang, Z; Zhang, S; Page, G; Jaworski, NW
The role of lactose in weanling pig nutrition: a literature and meta-analysis review.
J Anim Sci Biotechnol
12
10
2021
Sus scrofa, Suidae
Kurilshikov, A; Medina-Gomez, C; Bacigalupe, R; Radjabzadeh, D; Wang, J; Demirkan, A; Le Roy, CI; Raygoza Garay, JA; Finnicum, CT; Liu, X; Zhernakova, DV; Bonder, MJ; Hansen, TH; Frost, F; Rühlemann, MC; Turpin, W; Moon, JY; Kim, HN; Lüll, K; Barkan, E; Shah, SA; Fornage, M; Szopinska-Tokov, J; Wallen, ZD; Borisevich, D; Agreus, L; Andreasson, A; Bang, C; Bedrani, L; Bell, JT; Bisgaard, H; Boehnke, M; Boomsma, DI; Burk, RD; Claringbould, A; Croitoru, K; Davies, GE; van Duijn, CM; Duijts, L; Falony, G; Fu, J; van der Graaf, A; Hansen, T; Homuth, G; Hughes, DA; Ijzerman, RG; Jackson, MA; Jaddoe, VWV; Joossens, M; Jørgensen, T; Keszthelyi, D; Knight, R; Laakso, M; Laudes, M; Launer, LJ; Lieb, W; Lusis, AJ; Masclee, AAM; Moll, HA; Mujagic, Z; Qibin, Q; Rothschild, D; Shin, H; Sørensen, SJ; Steves, CJ; Thorsen, J; Timpson, NJ; Tito, RY; Vieira-Silva, S; Völker, U; Völzke, H; Võsa, U; Wade, KH; Walter, S; Watanabe, K; Weiss, S; Weiss, FU; Weissbrod, O; Westra, HJ; Willemsen, G; Payami, H; Jonkers, DMAE; Arias Vasquez, A; de Geus, EJC; Meyer, KA; Stokholm, J; Segal, E; Org, E; Wijmenga, C; Kim, HL; Kaplan, RC; Spector, TD; Uitterlinden, AG; Rivadeneira, F; Franke, A; Lerch, MM; Franke, L; Sanna, S; D'Amato, M; Pedersen, O; Paterson, AD; Kraaij, R; Raes, J; Zhernakova, A
Large-scale association analyses identify host factors influencing human gut microbiome composition.
Nat Genet
53
156-165
2021
Bifidobacterium, Homo sapiens, gut metagenome
Galieni, P; Travaglini, F; Vagnoni, D; Ruggieri, M; Caraffa, P; Bigazzi, C; Falcioni, S; Picardi, P; Mazzotta, S; Troiani, E; Dalsass, A; Mestichelli, F; Angelini, M; Camaioni, E; Maravalle, D; Angelini, S; Pezzoni, V
The detection of circulating plasma cells may improve the Revised International Staging System (R-ISS) risk stratification of patients with newly diagnosed multiple myeloma.
Br J Haematol
193
542-550
2021
Homo sapiens
Vorobiova, N; Usachova, E
INFLUENCE OF CARBOHYDRATE MALABSORPTION SYNDROME ON THE CLINICAL COURSE OF ROTAVIRUS INFECTION IN CHILDREN AT AN EARLY AGE.
Georgian Med News
120-125
2021
Rotavirus
Popadowska, A; Kempinska-Podhorodecka, A
Relation of the C/T-13910 LCT Polymorphism with Body Composition Measures and Their Modulation by Dairy Products in a Caucasian Men.
Am J Mens Health
15
15579883211007272
0
Homo sapiens
Singh, V; Singh, M; Friesen, CA
Colonic mucosal eosinophilia in children without inflammatory bowel disease.
Hum Pathol
113
34-38
2021
Homo sapiens
Nardone, OM; Manfellotto, F; D'Onofrio, C; Rocco, A; Annona, G; Sasso, F; De Luca, P; Imperatore, N; Testa, A; de Sire, R; Biffali, E; Castiglione, F
Lactose Intolerance Assessed by Analysis of Genetic Polymorphism, Breath Test and Symptoms in Patients with Inflammatory Bowel Disease.
Nutrients
13
2021
Homo sapiens
Qi, Q; Li, J; Yu, B; Moon, JY; Chai, JC; Merino, J; Hu, J; Ruiz-Canela, M; Rebholz, C; Wang, Z; Usyk, M; Chen, GC; Porneala, BC; Wang, W; Nguyen, NQ; Feofanova, EV; Grove, ML; Wang, TJ; Gerszten, RE; Dupuis, J; Salas-Salvadó, J; Bao, W; Perkins, DL; Daviglus, ML; Thyagarajan, B; Cai, J; Wang, T; Manson, JE; Martínez-González, MA; Selvin, E; Rexrode, KM; Clish, CB; Hu, FB; Meigs, JB; Knight, R; Burk, RD; Boerwinkle, E; Kaplan, RC
Host and gut microbial tryptophan metabolism and type 2 diabetes: an integrative analysis of host genetics, diet, gut microbiome and circulating metabolites in cohort studies.
Gut
2021
Bacteria, bacterium, Bifidobacterium
Demeekul, K; Sukumolanan, P; Bootcha, R; Panprom, C; Petchdee, S
A Cardiac Protection of Germinated Brown Rice During Cardiopulmonary Bypass Surgery and Simulated Myocardial Ischemia.
J Inflamm Res
14
3307-3319
2021
Metazoa
Hatch, TF; Lebenthal, E; Branski, D; Krasner, J
The effect of early postnatal acquired malnutrition on intestinal growth, disaccharidases and enterokinase.
J Nutr
109
1874-9
1979
Rattus
Buccigrossi, V; de Marco, G; Bruzzese, E; Ombrato, L; Bracale, I; Polito, G; Guarino, A
Lactoferrin induces concentration-dependent functional modulation of intestinal proliferation and differentiation.
Pediatr Res
61
410-4
2007
Homo sapiens, Bos taurus
James, PS; Smith, MW; Tivey, DR; Wilson, TJ
Epidermal growth factor selectively increases maltase and sucrase activities in neonatal piglet intestine.
J Physiol
393
583-94
1987
Sus scrofa
Gudmand-Høyer, E; Fenger, HJ; Kern-Hansen, P; Madsen, PR
Sucrase deficiency in Greenland. Incidence and genetic aspects.
Scand J Gastroenterol
22
24-8
1987
Homo sapiens
Nichols, BL; Avery, SE; Karnsakul, W; Jahoor, F; Sen, P; Swallow, DM; Luginbuehl, U; Hahn, D; Sterchi, EE
Congenital maltase-glucoamylase deficiency associated with lactase and sucrase deficiencies.
J Pediatr Gastroenterol Nutr
35
573-9
2002
Homo sapiens
Gudmand-Høyer, E; Fenger, HJ; Skovbjerg, H; Kern-Hansen, P; Madsen, PR
Trehalase deficiency in Greenland.
Scand J Gastroenterol
23
775-8
1988
Homo sapiens
Murray, IA; Coupland, K; Smith, JA; Ansell, ID; Long, RG
Intestinal trehalase activity in a UK population: establishing a normal range and the effect of disease.
Br J Nutr
83
241-5
2000
Homo sapiens
He, Z; Bolling, L; Tonb, D; Nadal, T; Mehta, DI
An automated method for the determination of intestinal disaccharidase and glucoamylase activities.
J Autom Methods Manag Chem
2006
93947
2006
Homo sapiens
Van Beers, EH; Al, RH; Rings, EH; Einerhand, AW; Dekker, J; Büller, HA
Lactase and sucrase-isomaltase gene expression during Caco-2 cell differentiation.
Biochem J
308 ( Pt 3)
769-75
1995
Homo sapiens
Van Beers, EH; Rings, EH; Taminiau, JA; Heymans, HS; Einerhand, AW; Dekker, J; Büller, HA
Regulation of lactase and sucrase-isomaltase gene expression in the duodenum during childhood.
J Pediatr Gastroenterol Nutr
27
37-46
1998
Homo sapiens
Belmont, JW; Reid, B; Taylor, W; Baker, SS; Moore, WH; Morriss, MC; Podrebarac, SM; Glass, N; Schwartz, ID
Congenital sucrase-isomaltase deficiency presenting with failure to thrive, hypercalcemia, and nephrocalcinosis.
BMC Pediatr
2
4
2002
Homo sapiens
Reinshagen, K; Keller, KM; Haase, B; Leeb, T; Naim, HY; Zimmer, KP
Mosaic pattern of sucrase isomaltase deficiency in two brothers.
Pediatr Res
63
79-83
2008
Homo sapiens
de Vrese, M; Keller, B; Barth, CA
Enhancement of intestinal hydrolysis of lactose by microbial beta-galactosidase (EC 3.2.1.23) of kefir.
Br J Nutr
67
67-75
1992
Bacteria, Areas
Fiedurek, J; Ilczuk, Z
Screening of microorganisms for improvement of beta-galactosidase production.
Acta Microbiol Pol
39
37-42
1990
Penicillium chrysogenum, moulds
Medow, MS; Thek, KD; Newman, LJ; Berezin, S; Glassman, MS; Schwarz, SM
Beta-galactosidase tablets in the treatment of lactose intolerance in pediatrics.
Am J Dis Child
144
1261-4
1990
Homo sapiens
Troelsen, JT; Olsen, J; Norén, O; Sjöström, H
A novel intestinal trans-factor (NF-LPH1) interacts with the lactase-phlorizin hydrolase promoter and co-varies with the enzymatic activity.
J Biol Chem
267
20407-11
1992
Homo sapiens, Suidae, Sus scrofa
Montgomery, RK; Büller, HA; Rings, EH; Grand, RJ
Lactose intolerance and the genetic regulation of intestinal lactase-phlorizin hydrolase.
FASEB J
5
2824-32
1991
Homo sapiens, Metazoa
Tanaka, T; Takase, S; Goda, T
A possible role of a nuclear factor NF-LPH1 in the regional expression of lactase-phlorizin hydrolase along the small intestine.
J Nutr Sci Vitaminol (Tokyo)
43
565-73
1997
Rattus
Järvelä, I; Sabri Enattah, N; Kokkonen, J; Varilo, T; Savilahti, E; Peltonen, L
Assignment of the locus for congenital lactase deficiency to 2q21, in the vicinity of but separate from the lactase-phlorizin hydrolase gene.
Am J Hum Genet
63
1078-85
1998
Homo sapiens
Zecca, L; Mesonero, JE; Stutz, A; Poirée, JC; Giudicelli, J; Cursio, R; Gloor, SM; Semenza, G
Intestinal lactase-phlorizin hydrolase (LPH): the two catalytic sites; the role of the pancreas in pro-LPH maturation.
FEBS Lett
435
225-8
1998
Homo sapiens
Mitchelmore, C; Troelsen, JT; Spodsberg, N; Sjöström, H; Norén, O
Interaction between the homeodomain proteins Cdx2 and HNF1alpha mediates expression of the lactase-phlorizin hydrolase gene.
Biochem J
346 Pt 2
529-35
2000
Sus scrofa, Mus musculus
Kuokkanen, M; Enattah, NS; Oksanen, A; Savilahti, E; Orpana, A; Järvelä, I
Transcriptional regulation of the lactase-phlorizin hydrolase gene by polymorphisms associated with adult-type hypolactasia.
Gut
52
647-52
2003
Homo sapiens
Wang, Z; Fang, R; Olds, LC; Sibley, E
Transcriptional regulation of the lactase-phlorizin hydrolase promoter by PDX-1.
Am J Physiol Gastrointest Liver Physiol
287
G555-61
2004
Homo sapiens, Mammalia
Chao, CK; Sibley, E
PCR-RFLP genotyping assay for a lactase persistence polymorphism upstream of the lactase-phlorizin hydrolase gene.
Genet Test
8
190-3
2004
Homo sapiens
Holmes, IH; Rodger, SM; Schnagl, RD; Ruck, BJ; Gust, ID; Bishop, RF; Barnes, GL
Is lactase the receptor and uncoating enzyme for infantile enteritis (rota) viruses?
Lancet
1
1387-8
1976
Homo sapiens, Human rotavirus, Metazoa, Rotavirus
Gossrau, R
[Azoindoxyl methods for the histochemical investigation of hydrolases. I. Lactase (lactase-beta-glucosidase complex) (author's transl)]
Histochemistry
48
111-9
1976
Rattus
Rao, MV; Dutta, SM
Lactase activity of microorganisms.
Folia Microbiol (Praha)
23
210-5
1978
Bacteria, yeasts
Arvanitakis, C; Chen, GH; Folscroft, J; Klotz, AP
Lactase deficiency--a comparative study of diagnostic methods.
Am J Clin Nutr
30
1597-602
1977
Homo sapiens
Cochet, B; Griessen, M; Vallotton, MC; Infante, E; Bérgoz, R
[Exhaled hydrogen test in the detection of lactase deficiency]
Schweiz Med Wochenschr
109
555-7
1979
Homo sapiens
Newcomer, AD; Hodgson, SF; McGill, DB; Thomas, PJ
Lactase deficiency: prevalence in osteoporosis.
Ann Intern Med
89
218-20
1978
Homo sapiens
Newcomer, AD; Gordon, H; Thomas, PJ; McGill, DB
Family studies of lactase deficiency in the American Indian.
Gastroenterology
73
985-8
1977
Homo sapiens
Kelch, L; Adlung, J; Grazikowske, H; Ritter, U
[Milk intolerance, lactose intolerance and lactase deficiency in partial resection of the stomach]
Chirurg
47
280-3
1976
Homo sapiens
Lisker, R; Gonzalez, B; Daltabuit, M
Recessive inheritance of the adult type of intestinal lactase deficiency.
Am J Hum Genet
27
662-4
1975
Homo sapiens
Lebenthal, E; Antonowicz, I; Shwachman, H
Correlation of lactase activity, lactose tolerance and milk consumption in different age groups.
Am J Clin Nutr
28
595-600
1975
Homo sapiens
Becciolini, A; Cariaggi, P; Gori, A
Behaviour of intestinal lactase after irradiation.
Strahlentherapie
150
145-8
1975
Rattus
Rivera-Sagredo, A; Cañada, FJ; Nieto, O; Jimenez-Barbero, J; MartÃn-Lomas, M
Substrate specificity of small-intestinal lactase. Assessment of the role of the substrate hydroxyl groups.
Eur J Biochem
209
415-22
1992
Mammalia
Liu, T; Reisenauer, AM; Castillo, RO
Ontogeny of intestinal lactase: posttranslational regulation by thyroxine.
Am J Physiol
263
G538-43
1992
Rattus, Metazoa
Rivera-Sagredo, A; Fernández-Mayoralas, A; Jiménez-Barbero, J; MartÃn-Lomas, M; Villanueva, D; Aragón, JJ
4-O-beta-D-galactopyranosyl-D-xylose: a new synthesis and application to the evaluation of intestinal lactase.
Carbohydr Res
228
129-35
1992
Rattus
Quak, SH; Brown, GA; Booth, IW; McNeish, AS
The nature of small bowel luminal fluid lactase.
Clin Chim Acta
204
145-54
1991
Homo sapiens
Jiang, TA; Ye, RY
Studies on small intestinal mucosal morphology lactase activity and lactose hydrolysis rate in childhood with diarrhea.
Chin Med J (Engl)
104
476-9
1991
Homo sapiens
Witte, J; Lloyd, M; Lorenzsonn, V; Korsmo, H; Olsen, W
The biosynthetic basis of adult lactase deficiency.
J Clin Invest
86
1338-42
1990
Homo sapiens
Eidsvoll, BE; Schjønsby, H
[Hydrogen breath tests in the diagnosis of primary lactase deficiency]
Tidsskr Nor Laegeforen
109
354-6
1989
Homo sapiens
Freund, JN; Duluc, I; Raul, F
Discrepancy between the intestinal lactase enzymatic activity and mRNA accumulation in sucklings and adults. Effect of starvation and thyroxine treatment.
FEBS Lett
248
39-42
1989
Suidae, Rattus
Cramer, DW
Lactase persistence and milk consumption as determinants of ovarian cancer risk.
Am J Epidemiol
130
904-10
1989
animal
Enck, P; Whitehead, WE
Lactase deficiency and lactose malabsorption. A review.
Z Gastroenterol
24
125-34
1986
Homo sapiens, Metazoa
Lami, F; Callegari, C; Tatali, M; Graziano, L; Guidetti, C; Miglioli, M; Barbara, L
Efficacy of addition of exogenous lactase to milk in adult lactase deficiency.
Am J Gastroenterol
83
1145-9
1988
Kluyveromyces lactis
Farley, FA; Healey, JH; Caparros-Sison, B; Godbold, J; Lane, JM; Glasser, DB
Lactase dehydrogenase as a tumor marker for recurrent disease in Ewing's sarcoma.
Cancer
59
1245-8
1987
Homo sapiens
Tsuboi, KK; Kwong, LK; D'Harlingue, AE; Stevenson, DK; Kerner, JA; Sunshine, P
The nature of maturational decline of intestinal lactase activity.
Biochim Biophys Acta
840
69-78
1985
Rattus
Pacifici, R; Droke, D; Avioli, LV
Intestinal lactase activity and calcium absorption in the aging female with osteoporosis.
Calcif Tissue Int
37
101-2
1985
Homo sapiens
Forget, P; Lombet, J; Grandfils, C; Dandrifosse, G; Geubelle, F
Lactase insufficiency revisited.
J Pediatr Gastroenterol Nutr
4
868-72
1985
Homo sapiens
Segal, I; Gagjee, PP; Essop, AR; Noormohamed, AM
Lactase deficiency in the South African black population.
Am J Clin Nutr
38
901-5
1983
Bos taurus
Ferguson, A; MacDonald, DM; Brydon, WG
Prevalence of lactase deficiency in British adults.
Gut
25
163-7
1984
Homo sapiens
Seetharam, B; Perrillo, R; Alpers, DH
Effect of pancreatic proteases on intestinal lactase activity.
Gastroenterology
79
827-32
1980
Homo sapiens
Berry, HK; Kellogg, FW; Lichstein, SR; Ingberg, RL
Elevated meconium lactase activity. Its use as a screening test for cystic fibrosis.
Am J Dis Child
134
930-4
1980
Homo sapiens
Simoons, FJ
A geographic approach to senile cataracts: possible links with milk consumption, lactase activity, and galactose metabolism.
Dig Dis Sci
27
257-64
1982
Homo sapiens, Mammalia
Flatz, G; Howell, JN; Doench, J; Flatz, SD
Distribution of physiological adult lactase phenotypes, lactose absorber and malabsorber, in Germany.
Hum Genet
62
152-7
1982
Homo sapiens
Newcomer, AD; McGill, DB
Irritable bowel syndrome. Role of lactase deficiency.
Mayo Clin Proc
58
339-41
1983
Pierinae
Abbas, H; Ahmad, M
Persistence of high intestinal lactase activity in Pakistan.
Hum Genet
64
277-8
1983
Homo sapiens
Cochet, B; Griessen, M; Balant, L; Infante, F; Vallotton, MC; Bergoz, R
[Diagnosis of lactase deficiency with the expired hydrogen (H2) test]
Schweiz Med Wochenschr
111
192-3
1981
Homo sapiens
Wang, Y; Harvey, CB; Pratt, WS; Sams, VR; Sarner, M; Rossi, M; Auricchio, S; Swallow, DM
The lactase persistence/non-persistence polymorphism is controlled by a cis-acting element.
Hum Mol Genet
4
657-62
1995
Homo sapiens
Freund, JN; Jost, B; Duluc, I; Morel, G
Ultrastructural study of intestinal lactase gene expression.
Biol Cell
83
211-7
1995
Rattus
Sahi, T
Hypolactasia and lactase persistence. Historical review and the terminology.
Scand J Gastroenterol Suppl
202
1-6
1994
Homo sapiens, Canis lupus familiaris, Mammalia
Fajardo, O; Naim, HY; Lacey, SW
The polymorphic expression of lactase in adults is regulated at the messenger RNA level.
Gastroenterology
106
1233-41
1994
Homo sapiens, Mammalia, Pierinae
Nudell, DM; Santiago, NA; Zhu, JS; Cohen, ML; Majuk, Z; Gray, GM
Intestinal lactase: maturational excess expression of mRNA over enzyme protein.
Am J Physiol
265
G1108-15
1993
Rattus, Metazoa
Maiuri, L; Rossi, M; Raia, V; Paparo, F; Garipoli, V; Auricchio, S
Surface staining on the villus of lactase protein and lactase activity in adult-type hypolactasia.
Gastroenterology
105
708-14
1993
Homo sapiens, Oryctolagus cuniculus, Rattus, Mammalia
Freund, JN; Jost, B; Lorentz, O; Duluc, I
Identification of homologues of the mammalian intestinal lactase gene in non-mammals (birds and molluscs).
Biochem J
322 ( Pt 2)
491-8
1997
Gallus gallus, Metazoa, Mammalia, animal
Harvey, CB; Hollox, EJ; Poulter, M; Wang, Y; Rossi, M; Auricchio, S; Iqbal, TH; Cooper, BT; Barton, R; Sarner, M; Korpela, R; Swallow, DM
Lactase haplotype frequencies in Caucasians: association with the lactase persistence/non-persistence polymorphism.
Ann Hum Genet
62 ( Pt 3)
215-23
1998
Homo sapiens
Meloni, T; Colombo, C; Ruggiu, G; Dessena, M; Meloni, GF
Primary lactase deficiency and past malarial endemicity in Sardinia.
Ital J Gastroenterol Hepatol
30
490-3
1998
Areas
O'Connor, TP; Diamond, J
Ontogeny of intestinal safety factors: lactase capacities and lactose loads.
Am J Physiol
276
R753-65
1999
Rattus
Bertron, P; Barnard, ND; Mills, M
Racial bias in federal nutrition policy, Part I: The public health implications of variations in lactase persistence.
J Natl Med Assoc
91
151-7
1999
Pierinae
Zecca, L; Mesonero, JE; Gloor, SM; Semenza, G
Species differences in the sites of cleavage of pro-lactase to lactase supports lack of selective pressure.
Biochim Biophys Acta
1435
51-60
1999
Homo sapiens, Oryctolagus cuniculus
Malone, AJ; Kearney, PJ; Duggan, PF
The effect of lactase and formula reconstitution on milk osmolality.
Int J Food Sci Nutr
50
311-7
1999
Bos taurus
Illanes, A; Wilson, L; Tomasello, G
Temperature optimization for reactor operation with chitin-immobilized lactase under modulated inactivation.
Enzyme Microb Technol
27
270-278
2000
Kluyveromyces marxianus var. marxianus
Hollox, EJ; Poulter, M; Zvarik, M; Ferak, V; Krause, A; Jenkins, T; Saha, N; Kozlov, AI; Swallow, DM
Lactase haplotype diversity in the Old World.
Am J Hum Genet
68
160-172
2001
Homo sapiens, Pan troglodytes
Feighery, L; Lynch, S; Kilmartin, C; Abuzakouk, M; Weir, D; Jackson, J; Feighery, C
Flow-cytometric detection of lactase expression in normal and coeliac intestinal epithelium.
Eur J Gastroenterol Hepatol
13
897-902
2001
Homo sapiens
von Tirpitz, C; Kohn, C; Steinkamp, M; Geerling, I; Maier, V; Möller, P; Adler, G; Reinshagen, M
Lactose intolerance in active Crohn's disease: clinical value of duodenal lactase analysis.
J Clin Gastroenterol
34
49-53
2002
Homo sapiens
Lee, SY; Madan, A; Furuta, GT; Colgan, SP; Sibley, E
Lactase gene transcription is activated in response to hypoxia in intestinal epithelial cells.
Mol Genet Metab
75
65-9
2002
Rattus
Gao, KP; Mitsui, T; Fujiki, K; Ishiguro, H; Kondo, T
Effect of lactase preparations in asymptomatic individuals with lactase deficiency--gastric digestion of lactose and breath hydrogen analysis.
Nagoya J Med Sci
65
21-8
2002
Aspergillus
Jiménez-Guzmán, J; Cruz-Guerrero, AE; RodrÃguez-Serrano, G; López-MunguÃa, A; Gómez-Ruiz, L; GarcÃa-Garibay, M
Enhancement of lactase activity in milk by reactive sulfhydryl groups induced by heat treatment.
J Dairy Sci
85
2497-502
2002
Kluyveromyces lactis
He, M; Yang, Y; Bian, L; Cui, H
[Effect of exogenous lactase on the absorption of lactose and its intolerance symptoms]
Wei Sheng Yan Jiu
28
309-11
1999
Homo sapiens
Sall, I; Férard, G
A new continuous automated assay for the determination of intestinal lactase.
Digestion
67
37-41
2003
Homo sapiens, Rattus
Poulter, M; Hollox, E; Harvey, CB; Mulcare, C; Peuhkuri, K; Kajander, K; Sarner, M; Korpela, R; Swallow, DM
The causal element for the lactase persistence/non-persistence polymorphism is located in a 1 Mb region of linkage disequilibrium in Europeans.
Ann Hum Genet
67
298-311
2003
Homo sapiens
Olds, LC; Sibley, E
Lactase persistence DNA variant enhances lactase promoter activity in vitro: functional role as a cis regulatory element.
Hum Mol Genet
12
2333-40
2003
Homo sapiens, Rattus
Swallow, DM
Genetics of lactase persistence and lactose intolerance.
Annu Rev Genet
37
197-219
2003
Homo sapiens, Mammalia
Troelsen, JT; Olsen, J; Møller, J; Sjöström, H
An upstream polymorphism associated with lactase persistence has increased enhancer activity.
Gastroenterology
125
1686-94
2003
Homo sapiens
Enattah, NS; Forsblom, C; Rasinperä, H; Tuomi, T; Groop, PH; Järvelä, I; ,
The genetic variant of lactase persistence C (-13910) T as a risk factor for type I and II diabetes in the Finnish population.
Eur J Clin Nutr
58
1319-22
2004
Homo sapiens
Mulcare, CA; Weale, ME; Jones, AL; Connell, B; Zeitlyn, D; Tarekegn, A; Swallow, DM; Bradman, N; Thomas, MG
The T allele of a single-nucleotide polymorphism 13.9 kb upstream of the lactase gene (LCT) (C-13.9kbT) does not predict or cause the lactase-persistence phenotype in Africans.
Am J Hum Genet
74
1102-10
2004
Homo sapiens
Bersaglieri, T; Sabeti, PC; Patterson, N; Vanderploeg, T; Schaffner, SF; Drake, JA; Rhodes, M; Reich, DE; Hirschhorn, JN
Genetic signatures of strong recent positive selection at the lactase gene.
Am J Hum Genet
74
1111-20
2004
Homo sapiens
Boyer, J; Brown, D; Liu, RH
In vitro digestion and lactase treatment influence uptake of quercetin and quercetin glucoside by the Caco-2 cell monolayer.
Nutr J
4
1
2005
Malus domestica, Homo sapiens, Allium cepa var. aggregatum
Högenauer, C; Hammer, HF; Mellitzer, K; Renner, W; Krejs, GJ; Toplak, H
Evaluation of a new DNA test compared with the lactose hydrogen breath test for the diagnosis of lactase non-persistence.
Eur J Gastroenterol Hepatol
17
371-6
2005
Homo sapiens
Troelsen, JT
Adult-type hypolactasia and regulation of lactase expression.
Biochim Biophys Acta
1723
19-32
2005
Homo sapiens, Mammalia
Kuokkanen, M; Butzow, R; Rasinperä, H; Medrek, K; Nilbert, M; Malander, S; Lubinski, J; Järvelä, I
Lactase persistence and ovarian carcinoma risk in Finland, Poland and Sweden.
Int J Cancer
117
90-4
2005
Homo sapiens
Valenkevich, LN; Iakhontova, OI
[Prevalence of the lactase deficiency among the population of the northwestern region of Russia]
Eksp Klin Gastroenterol
97-100, 108
2005
Homo sapiens
Szilagyi, A; Malolepszy, P; Yesovitch, S; Nathwani, U; Vinokuroff, C; Cohen, A; Xue, X
Inverse dose effect of pretest dietary lactose intake on breath hydrogen results and symptoms in lactase nonpersistent subjects.
Dig Dis Sci
50
2178-82
2005
Homo sapiens
Iqbal, TH; Bradley, R; Reilly, HM; Lewis, KO; Cooper, BT
Small intestinal lactase status, frequency distribution of enzyme activity and milk intake in a multi-ethnic population.
Clin Nutr
15
297-302
1996
Pierinae
Ingram, CJ; Elamin, MF; Mulcare, CA; Weale, ME; Tarekegn, A; Raga, TO; Bekele, E; Elamin, FM; Thomas, MG; Bradman, N; Swallow, DM
A novel polymorphism associated with lactose tolerance in Africa: multiple causes for lactase persistence?
Hum Genet
120
779-88
2007
Homo sapiens
Robayo-Torres, CC; Nichols, BL
Molecular differentiation of congenital lactase deficiency from adult-type hypolactasia.
Nutr Rev
65
95-8
2007
Homo sapiens
Torniainen, S; Hedelin, M; Autio, V; Rasinperä, H; Bälter, KA; Klint, A; Bellocco, R; Wiklund, F; Stattin, P; Ikonen, T; Tammela, TL; Schleutker, J; Grönberg, H; Järvelä, I
Lactase persistence, dietary intake of milk, and the risk for prostate cancer in Sweden and Finland.
Cancer Epidemiol Biomarkers Prev
16
956-61
2007
Homo sapiens
Weiskirchen, R; Tag, CG; Mengsteab, S; Gressner, AM; Ingram, CJ; Swallow, DM
Pitfalls in LightCycler diagnosis of the single-nucleotide polymorphism 13.9 kb upstream of the lactase gene that is associated with adult-type hypolactasia.
Clin Chim Acta
384
93-8
2007
Homo sapiens
Schirru, E; Corona, V; Usai-Satta, P; Scarpa, M; Cucca, F; De Virgiliis, S; Rossino, R; Frau, F; Macis, MD; Jores, RD; Congia, M
Decline of lactase activity and c/t-13910 variant in Sardinian childhood.
J Pediatr Gastroenterol Nutr
45
503-6
2007
Homo sapiens
Sun, HM; Qiao, YD; Chen, F; Xu, LD; Bai, J; Fu, SB
The lactase gene -13910T allele can not predict the lactase-persistence phenotype in north China.
Asia Pac J Clin Nutr
16
598-601
2007
Homo sapiens
Mattar, R; Monteiro, Mdo S; Villares, CA; dos Santos, AF; Carrilho, FJ
Single nucleotide polymorphism C/T(-13910), located upstream of the lactase gene, associated with adult-type hypolactasia: validation for clinical practice.
Clin Biochem
41
628-30
2008
Homo sapiens
Waud, JP; Matthews, SB; Campbell, AK
Measurement of breath hydrogen and methane, together with lactase genotype, defines the current best practice for investigation of lactose sensitivity.
Ann Clin Biochem
45
50-8
2008
Homo sapiens
Shrier, I; Szilagyi, A; Correa, JA
Impact of lactose containing foods and the genetics of lactase on diseases: an analytical review of population data.
Nutr Cancer
60
292-300
0
Bacteria
Smith, GD; Lawlor, DA; Timpson, NJ; Baban, J; Kiessling, M; Day, IN; Ebrahim, S
Lactase persistence-related genetic variant: population substructure and health outcomes.
Eur J Hum Genet
2008
Homo sapiens
Fabre, JW; Salehi, S; Eckley, L; Sawyer, GJ; Zhang, X; Dong, X; Freund, JN
INTESTINAL LACTASE AS AN AUTOLOGOUS β-GALACTOSIDASE REPORTER GENE FOR IN VIVO GENE EXPRESSION STUDIES.
Hum Gene Ther
2008
Homo sapiens, Mus musculus, Rattus, Metazoa
Bácsi, K; Hitre, E; Kósa, JP; Horváth, H; Lazáry, A; Lakatos, PL; Balla, B; Budai, B; Lakatos, P; Speer, G
Effects of the lactase 13910 C/T and calcium-sensor receptor A986S G/T gene polymorphisms on the incidence and recurrence of colorectal cancer in Hungarian population.
BMC Cancer
8
317
2008
Homo sapiens
Di Stefano, M; Terulla, V; Tana, P; Mazzocchi, S; Romero, E; Corazza, GR
Genetic test for lactase non-persistence and hydrogen breath test: Is genotype better than phenotype to diagnose lactose malabsorption?
Dig Liver Dis
2008
Homo sapiens
Ingram, CJ; Mulcare, CA; Itan, Y; Thomas, MG; Swallow, DM
Lactose digestion and the evolutionary genetics of lactase persistence.
Hum Genet
124
579-91
2009
Homo sapiens
Laaksonen, MM; Impivaara, O; Sievänen, H; Viikari, JS; Lehtimäki, TJ; Lamberg-Allardt, CJ; Kärkkäinen, MU; Välimäki, M; Heikkinen, J; Kröger, LM; Kröger, HP; Jurvelin, JS; Kähönen, MA; Raitakari, OT; ,
Associations of genetic lactase non-persistence and sex with bone loss in young adulthood.
Bone
44
1003-1009
2009
Homo sapiens
Coelho, M; Sequeira, F; Luiselli, D; Beleza, S; Rocha, J
On the edge of Bantu expansions: mtDNA, Y chromosome and lactase persistence genetic variation in southwestern Angola.
BMC Evol Biol
9
80
2009
Homo sapiens, Bos taurus
Torniainen, S; Savilahti, E; Järvelä, I
[Congenital lactase deficiency--a more common disease than previously thought?]
Duodecim
125
766-70
2009
Homo sapiens
Gerbault, P; Moret, C; Currat, M; Sanchez-Mazas, A
Impact of selection and demography on the diffusion of lactase persistence.
PLoS One
4
e6369
2009
Homo sapiens
Itan, Y; Powell, A; Beaumont, MA; Burger, J; Thomas, MG
The origins of lactase persistence in Europe.
PLoS Comput Biol
5
e1000491
2009
Homo sapiens
Itan, Y; Jones, BL; Ingram, CJ; Swallow, DM; Thomas, MG
A worldwide correlation of lactase persistence phenotype and genotypes.
BMC Evol Biol
10
36
2010
Homo sapiens
Pohl, D; Savarino, E; Hersberger, M; Behlis, Z; Stutz, B; Goetze, O; Eckardstein, AV; Fried, M; Tutuian, R
Excellent agreement between genetic and hydrogen breath tests for lactase deficiency and the role of extended symptom assessment.
Br J Nutr
1-8
2010
Homo sapiens
Velikodvorskaya, GA; Tikhonova, TV; Gurvits, ID; Karyagina, AS; Lavrova, NV; Sergienko, OV; Tashlitskii, VN; Lunina, NA; Lunin, VG
CHIMERIC LACTASE CAPABLE OF SPONTANEOUS AND STRONG IMMOBILIZATION ON CELLULOSE AND DEVELOPMENT OF A CONTINUOUS-FLOW SYSTEM FOR LACTOSE HYDROLYSIS AT HIGH TEMPERATURES.
Appl Environ Microbiol
2010
Thermoanaerobacter ethanolicus, Caldicellulosiruptor bescii, bacterium, Escherichia coli, plasmids, Transformation
Olds, LC; Ahn, JK; Sibley, E
-13915*G DNA polymorphism associated with lactase persistence in Africa interacts with Oct-1.
Hum Genet
2010
Homo sapiens
Janukonyté, J; Vestergaard, EM; Ladefoged, SA; Nissen, PH
High-resolution melting analysis using unlabeled probe and amplicon scanning simultaneously detects several lactase persistence variants.
Scand J Clin Lab Invest
2010
Homo sapiens
Tolonen, S; Laaksonen, M; Mikkilä, V; Sievänen, H; Mononen, N; Räsänen, L; Viikari, J; Raitakari, OT; Kähönen, M; Lehtimäki, TJ; ,
Lactase gene c/t(-13910) polymorphism, calcium intake, and pQCT bone traits in finnish adults.
Calcif Tissue Int
88
153-61
2011
Homo sapiens
Lokki, AI; Järvelä, I; Israelsson, E; Maiga, B; Troye-Blomberg, M; Dolo, A; Doumbo, OK; Meri, S; Holmberg, V
Lactase persistence genotypes and malaria susceptibility in Fulani of Mali.
Malar J
10
9
2011
Plasmodium falciparum, Homo sapiens, Bos taurus
Jensen, TG; Liebert, A; Lewinsky, R; Swallow, DM; Olsen, J; Troelsen, JT
The -14010*C variant associated with lactase persistence is located between an Oct-1 and HNF1? binding site and increases lactase promoter activity.
Hum Genet
2011
Homo sapiens
Nagy, D; Tömöry, G; Csányi, B; Bogácsi-Szabó, E; Czibula, A; Priskin, K; Bede, O; Bartosiewicz, L; Downes, CS; Raskó, I
Comparison of lactase persistence polymorphism in ancient and present-day Hungarian populations.
Am J Phys Anthropol
2011
animal
M?dry, E; Fidler, E; Sobczy?ska-Tomaszewska, A; Lisowska, A; Krzy?anowska, P; Pogorzelski, A; Minarowski, L; Oralewska, B; Mojs, E; Sapiejka, E; Marciniak, R; Sands, D; Korzon-Burakowska, A; Kwiecie?, J; Walkowiak, J
Mild CFTR mutations and genetic predisposition to lactase persistence in cystic fibrosis.
Eur J Hum Genet
2011
Homo sapiens
Schultheis, PJ; Bowling, BV
Analysis of a SNP linked to lactase persistence: An exercise for teaching molecular biology techniques to undergraduates.
Biochem Mol Biol Educ
39
133-40
2011
Homo sapiens
Sibley, E; Ahn, JK
Theodore E. Woodward Award: lactase persistence SNPs in African populations regulate promoter activity in intestinal cell culture.
Trans Am Clin Climatol Assoc
122
155-65
2010
Homo sapiens
Heyer, E; Brazier, L; Ségurel, L; Hegay, T; Austerlitz, F; Quintana-Murci, L; Georges, M; Pasquet, P; Veuille, M
Lactase persistence in central Asia: phenotype, genotype, and evolution.
Hum Biol
83
379-92
2011
Equus caballus
Grundmann, SA; Stratmann, E; Brehler, R; Luger, TA; Ständer, S
Lactase deficiency: a potential novel aetiological factor in chronic pruritus of unknown origin.
Acta Derm Venereol
91
698-703
2011
Homo sapiens
Plantinga, TS; Alonso, S; Izagirre, N; Hervella, M; Fregel, R; van der Meer, JW; Netea, MG; de la Rúa, C
Low prevalence of lactase persistence in Neolithic South-West Europe.
Eur J Hum Genet
2012
Homo sapiens, Bos taurus
Friedrich, DC; Callegari-Jacques, SM; Petzl-Erler, ML; Tsuneto, L; Salzano, FM; Hutz, MH
Stability or variation? Patterns of lactase gene and its enhancer region distributions in Brazilian Amerindians.
Am J Phys Anthropol
147
427-32
2012
Homo sapiens
Khabarova, Y; Grigoryeva, V; Tuomisto, S; Karhunen, PJ; Mattila, K; Isokoski, M
High prevalence of lactase non-persistence among indigenous nomadic Nenets, north-west Russia.
Int J Circumpolar Health
71
1-6
2012
Homo sapiens
Schlebusch, CM; Sjödin, P; Skoglund, P; Jakobsson, M
Stronger signal of recent selection for lactase persistence in Maasai than in Europeans.
Eur J Hum Genet
2012
Homo sapiens, collection
Travis, RC; Appleby, PN; Siddiq, A; Allen, NE; Kaaks, R; Canzian, F; Feller, S; Tjønneland, A; Johnsen, NF; Overvad, K; Quirós, JR; González, CA; Sánchez, MJ; Larrañaga, N; Chirlaque, MD; Barricarte, A; Khaw, KT; Wareham, N; Trichopoulou, A; Valanou, E; Oustoglou, E; Palli, D; Sieri, S; Tumino, R; Sacerdote, C; Bueno-de-Mesquita, HB; Stattin, P; Ferrari, P; Johansson, M; Norat, T; Riboli, E; Key, TJ
Genetic variation in the lactase gene, dairy product intake and risk for prostate cancer in the European prospective investigation into cancer and nutrition.
Int J Cancer
2012
Homo sapiens
Kumar, S; Ranjan, P; Mittal, B; Singh, R; Ghoshal, UC
Lactase persistence/non-persistence genetic variants in irritable bowel syndrome in an endemic area for lactose malabsorption.
J Gastroenterol Hepatol
2012
Homo sapiens
Wagh, K; Bhatia, A; Alexe, G; Reddy, A; Ravikumar, V; Seiler, M; Boemo, M; Yao, M; Cronk, L; Naqvi, A; Ganesan, S; Levine, AJ; Bhanot, G
Lactase persistence and lipid pathway selection in the Maasai.
PLoS One
7
e44751
2012
Homo sapiens
Basso, MS; Luciano, R; Ferretti, F; Muraca, M; Panetta, F; Bracci, F; Ottino, S; Diamanti, A
Association between celiac disease and primary lactase deficiency.
Eur J Clin Nutr
66
1364-5
2012
Homo sapiens
Hermida, C; Guerra, P; Martínez-Costa, OH; Sánchez, V; Sánchez, JJ; Solera, J; Fernández-Mayoralas, A; Codoceo, R; Frías, J; Aragón, JJ
Phase I and Phase IB Clinical Trials for the Noninvasive Evaluation of Intestinal Lactase With 4-Galactosylxylose (Gaxilose).
J Clin Gastroenterol
2013
Homo sapiens, collection
Ruchkina, IN; Fadeeva, NA; Parfenov, AI; Shcherbakov, PL; Gubina, AV; Poleva, NI; Khomeriki, SG; Chikunova, BZ
[The role of small bowel microflora in the development of secondary lactase deficiency and the possibilities of its treatment with probiotics].
Ter Arkh
85
21-6
2013
Homo sapiens
Zhu, Y; Zheng, X; Cong, Y; Chu, H; Fried, M; Dai, N; Fox, M
Bloating and distention in irritable bowel syndrome: the role of gas production and visceral sensation after lactose ingestion in a population with lactase deficiency.
Am J Gastroenterol
108
1516-25
2013
Homo sapiens
Jones, BL; Raga, TO; Liebert, A; Zmarz, P; Bekele, E; Danielsen, ET; Olsen, AK; Bradman, N; Troelsen, JT; Swallow, DM
Diversity of lactase persistence alleles in ethiopia: signature of a soft selective sweep.
Am J Hum Genet
93
538-44
2013
Homo sapiens, Mammalia
Sverrisdóttir, OÓ; Timpson, A; Toombs, J; Lecoeur, C; Froguel, P; Carretero, JM; Arsuaga Ferreras, JL; Götherström, A; Thomas, MG
Direct estimates of natural selection in iberia indicate calcium absorption was not the only driver of lactase persistence in europe.
Mol Biol Evol
31
975-83
2014
Homo sapiens, Mammalia
Krüttli, A; Bouwman, A; Akgül, G; Della Casa, P; Rühli, F; Warinner, C
Ancient DNA analysis reveals high frequency of European lactase persistence allele (T-13910) in medieval central europe.
PLoS One
9
e86251
2014
Homo sapiens, Mammalia
Pruimboom, L; Fox, T; Muskiet, FA
Lactase persistence and augmented salivary alpha-amylase gene copy numbers might have been selected by the combined toxic effects of gluten and (food born) pathogens.
Med Hypotheses
82
326-34
2014
Homo sapiens, Bos taurus, animal
Ranciaro, A; Campbell, MC; Hirbo, JB; Ko, WY; Froment, A; Anagnostou, P; Kotze, MJ; Ibrahim, M; Nyambo, T; Omar, SA; Tishkoff, SA
Genetic origins of lactase persistence and the spread of pastoralism in Africa.
Am J Hum Genet
94
496-510
2014
Homo sapiens
Breton, G; Schlebusch, CM; Lombard, M; Sjödin, P; Soodyall, H; Jakobsson, M
Lactase Persistence Alleles Reveal Partial East African Ancestry of Southern African Khoe Pastoralists.
Curr Biol
2014
Homo sapiens, Namibia
Macholdt, E; Lede, V; Barbieri, C; Mpoloka, SW; Chen, H; Slatkin, M; Pakendorf, B; Stoneking, M
Tracing Pastoralist Migrations to Southern Africa with Lactase Persistence Alleles.
Curr Biol
2014
Namibia
Gerbault, P
The onset of lactase persistence in Europe.
Hum Hered
76
154-61
2013
Homo sapiens, Mammalia
Macholdt, E; Slatkin, M; Pakendorf, B; Stoneking, M
New insights into the history of the C-14010 lactase persistence variant in Eastern and Southern Africa.
Am J Phys Anthropol
2014
Homo sapiens
Friedrich, DC; de Andrade, FM; Fiegenbaum, M; de Almeida, S; Mattevi, VS; Callegari-Jacques, SM; Hutz, MH
The lactase persistence genotype is a protective factor for the metabolic syndrome.
Genet Mol Biol
37
611-5
2014
Homo sapiens
Sun, J; Lin, J; Parashette, K; Zhang, J; Fan, R
Association of lymphocytic colitis and lactase deficiency in pediatric population.
Pathol Res Pract
211
138-44
2015
Homo sapiens
Fadeeva, NA; Ruchkina, IN; Parfenov, AI; Shcherbakov, PL
[Small intestinal bacterial overgrowth as a cause of lactase deficiency].
Ter Arkh
87
20-3
2015
Bacteria, Homo sapiens
Diekmann, L; Pfeiffer, K; Naim, HY
Congenital lactose intolerance is triggered by severe mutations on both alleles of the lactase gene.
BMC Gastroenterol
15
36
2015
Homo sapiens
Jones, BL; Oljira, T; Liebert, A; Zmarz, P; Montalva, N; Tarekeyn, A; Ekong, R; Thomas, MG; Bekele, E; Bradman, N; Swallow, DM
Diversity of lactase persistence in African milk drinkers.
Hum Genet
134
917-25
2015
Clinitrachus argentatus
Stöcker, B; Grundmann, S; Mosters, P; Nitzsche, P; Brehler, R
Occupational sensitization to lactase in the dietary supplement industry.
Arch Environ Occup Health
1-9
2015
Homo sapiens, bat, plant
De Fanti, S; Sazzini, M; Giuliani, C; Frazzoni, F; Sarno, S; Boattini, A; Marasco, E; Mantovani, V; Franceschi, C; Moral, P; Garagnani, P; Luiselli, D
Inferring the genetic history of lactase persistence along the Italian peninsula from a large genomic interval surrounding the LCT gene.
Am J Phys Anthropol
158
708-18
2015
Homo sapiens
Fazeli, W; Kaczmarek, S; Kirschstein, M; Santer, R
A novel mutation within the lactase gene (LCT): the first report of congenital lactase deficiency diagnosed in Central Europe.
BMC Gastroenterol
15
90
2015
Homo sapiens
Fernández, CI; Montalva, N; Arias, M; Hevia, M; Moraga, ML; Flores, SV
Lactase non-persistence and general patterns of dairy intake in indigenous and mestizo chilean populations.
Am J Hum Biol
28
213-9
2016
Santiago
Wahlqvist, ML
Lactose nutrition in lactase nonpersisters.
Asia Pac J Clin Nutr
24 Suppl 1
S21-5
2015
Homo sapiens, gut metagenome
Hassan, HY; van Erp, A; Jaeger, M; Tahir, H; Oosting, M; Joosten, LA; Netea, MG
Genetic diversity of lactase persistence in East African populations.
BMC Res Notes
9
8
2016
Homo sapiens, Colotis, Arabia
Paz-Y-Miño, C; Burgos, G; López-Cortés, A; Herrera, C; Gaviria, A; Tejera, E; Cabrera-Andrade, A
A study of the molecular variants associated with lactase persistence in different Ecuadorian ethnic groups.
Am J Hum Biol
2016
Homo sapiens
Labrie, V; Buske, OJ; Oh, E; Jeremian, R; Ptak, C; Gasi?nas, G; Maleckas, A; Petereit, R; Žvirbliene, A; Adamonis, K; Kriukien?, E; Koncevi?ius, K; Gordevi?ius, J; Nair, A; Zhang, A; Ebrahimi, S; Oh, G; Šikšnys, V; Kup?inskas, L; Brudno, M; Petronis, A
Lactase nonpersistence is directed by DNA-variation-dependent epigenetic aging.
Nat Struct Mol Biol
23
566-73
2016
Homo sapiens, Mammalia
Enko, D; Pollheimer, V; Németh, S; Pühringer, H; Stolba, R; Halwachs-Baumann, G; Kriegshäuser, G
Lactase Non-Persistence Genotyping: Comparison of Two Real-Time PCR Assays and Assessment of Concomitant Fructose/Sorbitol Malabsorption Rates.
Clin Lab
62
727-30
2016
Homo sapiens
Buzás, G; Fodor, F; Csókay, B
[Accuracy of lactase gene C/T-13910 polymorphism and hydrogen breath test in a gastroenterology outpatient clinic: a retrospective study].
Orv Hetil
157
1007-12
2016
Homo sapiens
Hilliard, CB
High osteoporosis risk among East Africans linked to lactase persistence genotype.
Bonekey Rep
5
803
2016
animal
Felicilda-Reynaldo, RF; Kenneally, M
Digestive Enzyme Replacement Therapy: Pancreatic Enzymes and Lactase.
Medsurg Nurs
25
182-5
0
Homo sapiens
Liebert, A; Jones, BL; Danielsen, ET; Olsen, AK; Swallow, DM; Troelsen, JT
In Vitro Functional Analyses of Infrequent Nucleotide Variants in the Lactase Enhancer Reveal Different Molecular Routes to Increased Lactase Promoter Activity and Lactase Persistence.
Ann Hum Genet
80
307-318
2016
Homo sapiens
Szilagyi, A; Xue, X
Geographic associations between lactase phenotype, multiple sclerosis, and inflammatory bowel diseases; Does obesity trump geography?
Med Hypotheses
96
68-72
2016
Homo sapiens
Voisin, MR; Borici-Mazi, R
Anaphylaxis to supplemental oral lactase enzyme.
Allergy Asthma Clin Immunol
12
66
2016
Bacteria, Aspergillus niger, Homo sapiens
Oh, E; Jeremian, R; Oh, G; Groot, D; Susic, M; Lee, K; Foy, K; Laird, PW; Petronis, A; Labrie, V
Transcriptional heterogeneity in the lactase gene within cell-type is linked to the epigenome.
Sci Rep
7
41843
2017
Mus musculus
Khabarova, Y; Grigoryeva, V; Tuomisto, S; Karhunen, P; Mattila, K; Isokoski, M
High prevalence of lactase non-persistence among indigenous nomadic Nenets, north-west Russia.
Int J Circumpolar Health
71
17898
2012
Homo sapiens
Traffano-Schiffo, MV; Aguirre Calvo, TR; Castro-Giraldez, M; Fito, PJ; Santagapita, PR
Alginate Beads Containing Lactase: Stability and Microstructure.
Biomacromolecules
18
1785-1792
2017
Cyamopsis tetragonoloba
Hubácek, JA; Adámková, V; Šedová, L; Olišarová, V; Adámek, V; Tóthová, V
Frequency of adult type-associated lactase persistence LCT-13910C/T genotypes in the Czech/Slav and Czech Roma/Gypsy populations.
Genet Mol Biol
40
450-452
0
Homo sapiens
Venkateswarulu, TC; Prabhakar, KV; Kumar, RB
Optimization of nutritional components of medium by response surface methodology for enhanced production of lactase.
3 Biotech
7
202
2017
Bacillus subtilis, Saccharomyces cerevisiae
Ben Halima, Y; Kefi, R; Sazzini, M; Giuliani, C; De Fanti, S; Nouali, C; Nagara, M; Mengozzi, G; Elouej, S; Abid, A; Jamoussi, H; Chouchane, L; Romeo, G; Abdelhak, S; Luiselli, D
Lactase persistence in Tunisia as a result of admixture with other Mediterranean populations.
Genes Nutr
12
20
2017
Homo sapiens
Liebert, A; López, S; Jones, BL; Montalva, N; Gerbault, P; Lau, W; Thomas, MG; Bradman, N; Maniatis, N; Swallow, DM
World-wide distributions of lactase persistence alleles and the complex effects of recombination and selection.
Hum Genet
136
1445-1453
2017
Homo sapiens
Traffano-Schiffo, MV; Castro-Giraldez, M; Fito, PJ; Perullini, M; Santagapita, PR
Gums induced microstructure stability in Ca(II)-alginate beads containing lactase analyzed by SAXS.
Carbohydr Polym
179
402-407
2018
Cyamopsis tetragonoloba
Leseva, MN; Grand, RJ; Klett, H; Boerries, M; Busch, H; Binder, AM; Michels, KB
Differences in DNA Methylation and Functional Expression in Lactase Persistent and Non-persistent Individuals.
Sci Rep
8
5649
2018
Homo sapiens
Leksmono, CS; Manzoni, C; Tomkins, JE; Lucchesi, W; Cottrell, G; Lewis, PA
Measuring Lactase Enzymatic Activity in the Teaching Lab.
J Vis Exp
2018
Homo sapiens
Boeva, VI; Kokorina, OV; Archba, RR; Dvoryanchikov, VV; Kolhyubaeva, SN
[The influence of the vitamin D3 level in the blood serum of lactase gene polymorphism on the development of chronic polypous rhinosinusitis].
Vestn Otorinolaringol
83
49-54
0
Homo sapiens
Hoang, TT; Lei, Y; Mitchell, LE; Sharma, SV; Swartz, MD; Waller, DK; Finnell, RH; Benjamin, RH; Browne, ML; Canfield, MA; Lupo, PJ; McKenzie, P; Shaw, G; Agopian, AJ; ,
Maternal Lactase Polymorphism (rs4988235) Is Associated with Neural Tube Defects in Offspring in the National Birth Defects Prevention Study.
J Nutr
2019
Homo sapiens
Charati, H; Peng, MS; Chen, W; Yang, XY; Jabbari Ori, R; Aghajanpour-Mir, M; Esmailizadeh, A; Zhang, YP
The evolutionary genetics of lactase persistence in seven ethnic groups across the Iranian plateau.
Hum Genomics
13
7
2019
Homo sapiens
Abaturov, AY; Stepanov, YM; Nikulina, AA
Treatment of lactase deficiency in children's obesity with genotype c/c 13910 of lactase gene.
Wiad Lek
72
17-21
2019
Homo sapiens
Dong, L; Zhong, Q
Dispersible Biopolymer Particles Loaded with Lactase as a Potential Delivery System To Control Lactose Hydrolysis in Milk.
J Agric Food Chem
67
6559-6568
2019
Beta vulgaris subsp. vulgaris, Electron
Souza, CJF; Comunian, TA; Kasemodel, MGC; Favaro-Trindade, CS
Microencapsulation of lactase by W/O/W emulsion followed by complex coacervation: Effects of enzyme source, addition of potassium and core to shell ratio on encapsulation efficiency, stability and kinetics of release.
Food Res Int
121
754-764
2019
Kluyveromyces lactis
Kuchay, RAH
New insights into the molecular basis of lactase non-persistence/persistence: a brief review.
Drug Discov Ther
14
1-7
2020
Mammalia
Fung, M; Xue, X; Szilagyi, A
Estimating Lactase Nonpersistence Distributions in the Multi-Ethnic Canadian Demographic: A Population-Based Study.
J Can Assoc Gastroenterol
3
103-110
2020
Homo sapiens
Segurel, L; Guarino-Vignon, P; Marchi, N; Lafosse, S; Laurent, R; Bon, C; Fabre, A; Hegay, T; Heyer, E
Why and when was lactase persistence selected for? Insights from Central Asian herders and ancient DNA.
PLoS Biol
18
e3000742
2020
Homo sapiens, Metazoa
Priehodová, E; Austerlitz, F; ?ížková, M; Nová?ková, J; Ricaut, FX; Hofmanová, Z; Schlebusch, CM; ?erný, V
Sahelian pastoralism from the perspective of variants associated with lactase persistence.
Am J Phys Anthropol
173
423-436
2020
Bos taurus
Burger, J; Link, V; Blöcher, J; Schulz, A; Sell, C; Pochon, Z; Diekmann, Y; Žegarac, A; Hofmanová, Z; Winkelbach, L; Reyna-Blanco, CS; Bieker, V; Orschiedt, J; Brinker, U; Scheu, A; Leuenberger, C; Bertino, TS; Bollongino, R; Lidke, G; Stefanovi?, S; Jantzen, D; Kaiser, E; Terberger, T; Thomas, MG; Veeramah, KR; Wegmann, D
Low Prevalence of Lactase Persistence in Bronze Age Europe Indicates Ongoing Strong Selection over the Last 3,000 Years.
Curr Biol
2020
Homo sapiens
Joslin, SEK; Durbin-Johnson, BP; Britton, M; Settles, ML; Korf, I; Lemay, DG
Association of the Lactase Persistence Haplotype Block With Disease Risk in Populations of European Descent.
Front Genet
11
558762
2020
Homo sapiens
Baijal, R; Tandon, RK
Effect of lactase on symptoms and hydrogen breath levels in lactose intolerance: A crossover placebo-controlled study.
JGH Open
5
143-148
2021
Homo sapiens
Hollfelder, N; Babiker, H; Granehäll, L; Schlebusch, CM; Jakobsson, M
The Genetic Variation of Lactase Persistence Alleles in Sudan and South Sudan.
Genome Biol Evol
13
2021
Homo sapiens
Simoons FJ
Persistence of lactase activity among Northern Europeans: a weighing of evidence for the calcium absorption hypothesis.
Ecology of food and nutrition
40
397-469
2001
Homo sapiens
Welsh, JD; Poley, JR; Bhatia, M; Stevenson, DE
Intestinal disaccharidase activities in relation to age, race, and mucosal damage.
Gastroenterology
75
847-55
1978
Homo sapiens, Pierinae
Lee, JH; Griffiths, WJ; Zantout, I; Welsh, JD
Adequacy of endoscopic biopsy specimens for disaccharidase assays.
Am J Dig Dis
23
1129-31
1978
Homo sapiens, Areas
Greene, HL; McCabe, DR; Merenstein, GB
Protracted diarrhea and malnutrition in infancy: Changes in intestinal morphology and disaccharidase activities during treatment with total intravenous nutrition or oral elemental diets.
J Pediatr
87
695-704
1975
Homo sapiens
Perlow, W; Baraona, E; Lieber, CS
Symptomatic intestinal disaccharidase deficiency in alcoholics.
Gastroenterology
72
680-4
1977
Homo sapiens, Pierinae
Jennings, W; Rowland, R; Hecker, R; Gibson, GE; Fitch, RJ; Reid, DP
The significance of lowered jejunal disaccharidase levels.
Aust N Z J Med
6
556-60
1976
Giardia intestinalis
Yoshida, Y; Sasaki, G; Goto, S; Yanagiya, S; Nakasato, N
Studies of ultramicrostructure in relation to disaccharidase activity in the jejunal mucosa.
Gastroenterol Jpn
10
141-5
1975
Homo sapiens, Electron, animal
Wang, X
[An approach to the preparation of digestive enzyme-drug for oral administration: enteric-soluble disaccharidase microcapsules]
Zhongguo Yi Xue Ke Xue Yuan Xue Bao
14
155-8
1992
Saccharomyces cerevisiae
Holt, PR; Yeh, KY
Effects of starvation and refeeding on jejunal disaccharidase activity.
Dig Dis Sci
37
827-32
1992
Rattus
Sterchi, EE; Lentze, MJ; Naim, HY
Molecular aspects of disaccharidase deficiencies.
Baillieres Clin Gastroenterol
4
79-96
1990
insertion sequences, Homo sapiens
Lembcke, B; Schneider, H; Lankisch, PG
Is the assay of disaccharidase activity in small bowel mucosal biopsy relevant for clinical gastroenterologists?
Klin Wochenschr
67
568-75
1989
Homo sapiens
Mayne, AJ; Brown, GA; Sule, D; McNeish, AS
Postnatal development of disaccharidase activities in jejunal fluid of preterm neonates.
Gut
27
1357-61
1986
Homo sapiens
Lembcke, B; Fölsch, UR; Creutzfeldt, W
Effect of 1-desoxynojirimycin derivatives on small intestinal disaccharidase activities and on active transport in vitro.
Digestion
31
120-7
1985
Rattus
Stern, M; Plettner, C
[Disaccharidase activity as a diagnostic criterion for the mucosa of the small intestine]
Monatsschr Kinderheilkd
131
264-8
1983
Homo sapiens
Römer, H; Urbach, R; Gomez, MA; Lopez, A; Perozo-Ruggeri, G; Vegas, ME
Moderate and severe protein energy malnutrition in childhood: effects on jejunal mucosal morphology and disaccharidase activities.
J Pediatr Gastroenterol Nutr
2
459-64
1983
Homo sapiens
Bjarnason, I; Batt, R; Catt, S; Macpherson, A; Maxton, D; Menzies, IS
Evaluation of differential disaccharide excretion in urine for non-invasive investigation of altered intestinal disaccharidase activity caused by alpha-glucosidase inhibition, primary hypolactasia, and coeliac disease.
Gut
39
374-81
1996
Homo sapiens
Salomon, R; Levy, E; Levesque, D; Szilagyi, A; Seidman, E
Caco-2 cell disaccharidase activities are unaffected by gestational hormones.
Can J Physiol Pharmacol
74
1126-31
1996
Homo sapiens, Metazoa
Kaufman, SS; Wisecarver, JL; Ruby, EI; Fox, IJ; Sudan, DL; Pillen, TJ; Dhawan, A; Horslen, SP; Vanderhoof, JA; Radio, SJ; Markin, RS; Langnas, AN
Correlation of mucosal disaccharidase activities with histology in evaluation of rejection following intestinal transplantation.
Pediatr Transplant
2
134-8
1998
Homo sapiens
Park, YK; Monaco, MH; Donovan, SM
Enteral insulin-like growth factor-I augments intestinal disaccharidase activity in piglets receiving total parenteral nutrition.
J Pediatr Gastroenterol Nutr
29
198-206
1999
Suidae
Enattah, NS; Kuokkanen, M; Forsblom, C; Natah, S; Oksanen, A; Jarvela, I; Peltonen, L; Savilahti, E
Correlation of intestinal disaccharidase activities with the C/T-13910 variant and age.
World J Gastroenterol
13
3508-12
2007
Homo sapiens
Solaymani-Mohammadi, S; Singer, SM
Host Immunity and Pathogen Strain Contribute to Intestinal Disaccharidase Impairment following Gut Infection.
J Immunol
2011
Mus sp.
Sanaksenaho, G; Mutanen, A; Koivusalo, AI; Merras-Salmio, L; Pakarinen, MP
Duodenal Disaccharidase Activities During and After Weaning Off Parenteral Nutrition in Pediatric Intestinal Failure.
J Pediatr Gastroenterol Nutr
2016
Homo sapiens
Viswanathan, L; Rao, SSC; Kennedy, K; Sharma, A; Yan, Y; Jimenez, E
Prevalence of Disaccharidase Deficiency in Adults With Unexplained Gastrointestinal Symptoms.
J Neurogastroenterol Motil
26
384-390
2020
Homo sapiens
Srinathan, SK; Langer, JC; Wang, JL; Rubin, DC
Enterocytic gene expression is altered in experimental gastroschisis.
J Surg Res
68
1-6
1997
Metazoa, Oryctolagus cuniculus
Børkje, B; Odegaard, S; Vetvik, K; Skagen, DW; Andersen, KJ; Laerum, OD
Influence of remote cancer and obesity on, and distribution of mucosal enzymes in, the upper small intestine.
Scand J Gastroenterol
21
928-34
1986
Homo sapiens
Chen, SL; Frank, JF; Loewenstein, M
Estimation of lactose hydrolysis by freezing point measurements in milk and whey substrates treated with lactases from various microorganisms.
J Assoc Off Anal Chem
64
1414-9
1981
Aspergillus niger
Woliński, J; Biernat, M; Guilloteau, P; Weström, BR; Zabielski, R
Exogenous leptin controls the development of the small intestine in neonatal piglets.
J Endocrinol
177
215-22
2003
Metazoa
Guggenbichler, JP; Stickler, GB
[Old and new data on diarrhetic diseases in childhood I. Etiology and pathophysiology]
Infection
3
127-42
1975
Bacteria
Chao, KC; Haugen, MM; Royer, GP
Stabilization of kappa-carrageenan gel with polymeric amines: Use of immobilized cells as biocatalysts at elevated temperatures.
Biotechnol Bioeng
28
1289-93
1986
Flavobacterium sp., Geobacillus stearothermophilus, Saccharomyces cerevisiae
Bernstein, D; Bell, JG; Kwong, L; Castillo, RO
Alterations in postnatal intestinal function during chronic hypoxemia.
Pediatr Res
31
234-8
1992
Homo sapiens, Ovis aries
Le Huerou, I; Guilloteau, P; Wicker, C; Mouats, A; Chayvialle, JA; Bernard, C; Burton, J; Toullec, R; Puigserver, A
Activity distribution of seven digestive enzymes along small intestine in calves during development and weaning.
Dig Dis Sci
37
40-6
1992
Metazoa
Raul, F; Gosse, F; Doffoel, M; Darmenton, P; Wessely, JY
Age related increase of brush border enzyme activities along the small intestine.
Gut
29
1557-63
1988
Metazoa
Danielsen, EM; Sjöström, H; Norén, O; Bro, B; Dabelsteen, E
Biosynthesis of intestinal microvillar proteins. Characterization of intestinal explants in organ culture and evidence for the existence of pro-forms of the microvillar enzymes.
Biochem J
202
647-54
1982
Metazoa
Montagne, L; Toullec, R; Savidge, T; Lallès, JP
Morphology and enzyme activities of the small intestine are modulated by dietary protein source in the preruminant calf.
Reprod Nutr Dev
39
455-66
0
Glycine max, Cannula
Górka, P; Pietrzak, P; Kotunia, A; Zabielski, R; Kowalski, ZM
Effect of method of delivery of sodium butyrate on maturation of the small intestine in newborn calves.
J Dairy Sci
97
1026-35
2014
Metazoa, Zea mays subsp. mays
Montagne L;Salgado P;Toullec R;Lalles JP
Enzymes of the small intestine of the calf: effect of dietary protein source on the activities of some enzymes in the small intestinal mucosa and digesta
Journal of the science of food and agriculture
82
1772-1779
2002
Solanum tuberosum
Zhu, YH; Wang, QB; Gu, HC; Wang, SL; Gao, F
[Preparation of surface functional magnetic microspheres and their application in nucleic acid separation and enzyme immobilization]
Zhongguo Yi Xue Ke Xue Yuan Xue Bao
24
118-23
2002
Electron
Leng-Peschlow, E
Interference of dietary fibres with gastrointestinal enzymes in vitro.
Digestion
44
200-10
1989
Medicago sativa, Triticum aestivum
Trahair, JF; Sangild, PT
Systemic and luminal influences on the perinatal development of the gut.
Equine Vet J Suppl
40-50
1997
Sus scrofa, Ovis aries
Lebenthal, A; Lebenthal, E
The ontogeny of the small intestinal epithelium.
JPEN J Parenter Enteral Nutr
23
S3-6
0
Homo sapiens
Ivanov, E; Petrova, S; Adjarov, D; Naidenova, E
Influence of D-galactosamine and alpha-naphthylisothiocyanate on the activities of some intestinal enzymes.
Hepatogastroenterology
31
236-8
1984
Rattus
De Curtis, M; Vetrano, G
[Absorption of proteins, carbohydrates and fats in the preterm neonate]
Pediatr Med Chir
8
437-42
0
Homo sapiens
Diao, H; Zheng, P; Yu, B; He, J; Mao, X; Yu, J; Chen, D
Effects of benzoic Acid and thymol on growth performance and gut characteristics of weaned piglets.
Asian-Australas J Anim Sci
28
827-39
2015
Suidae
Stevenson, NR; Sitren, HS
Regional variability in circadian rhythmicity of intestinal digestive-absorptive functions.
Int J Chronobiol
6
119-34
1979
Rattus
Stevenson, NR; Ferrigni, F; Parnicky, K; Day, S; Fierstein, JS
Effect of changes in feeding schedule on the diurnal rhythms and daily activity levels of intestinal brush border enzymes and transport systems.
Biochim Biophys Acta
406
131-45
1975
Rattus
Ugolev, AM; De Laey, P; Iezuitova, NN; Rakhimov, KR; Timofeeva, NM; Stepanova, AT
Membrane digestion and nutrient assimilation in early development.
Ciba Found Symp
221-46
0
Rattus
Pergolizzi, R; Lifshitz, F; Teichberg, S; Wapnir, RA
Interaction between dietary carbohydrates and intestinal disaccharidases in experimental diarrhea.
Am J Clin Nutr
30
482-9
1977
Rattus
McNicholl, B; Egan-Mitchell, B; Stevens, F; Keane, R; Baker, S; McCarthy, CF; Fottrell, PF
Mucosal recovery in treated childhood celiac disease (gluten-sensitive enteropathy).
J Pediatr
89
418-24
1976
Homo sapiens
Gracey, M; Thomas, J; Houghton, M
Effect of stasis on intestinal enzyme activities.
Aust N Z J Med
5
141-4
1975
Rattus, Metazoa
Caspary, WF; Winckler, K; Lankisch, PG; Creutzfeldt, W
Influence of exocrine and endocrine pancreatic function on intestinal brush border enaymatic activities.
Gut
16
89-92
1975
Homo sapiens
Gracey, M; Houghton, M; Thomas, J
Deoxycholate depresses small-intestinal enzyme activity.
Gut
16
53-6
1975
Rattus
Phillips, AD; Smith, MW; Walker-Smith, JA
Selective alteration of brush-border hydrolases in intestinal diseases in childhood.
Clin Sci (Lond)
74
193-200
1988
Homo sapiens
Børkje, B; Laerum, OD; Schrumpf, E
Enzyme activities in biopsy specimens from large-bowel mucosa in colorectal adenomas and carcinomas.
Scand J Gastroenterol
22
533-8
1987
Homo sapiens
Adler, G; Hausmann, W; Elsebach, K; Goke, B; Lorenz-Meyer, H; Herberg, L; Arnold, R
Effect of pancreatic atrophy and hypertrophy on the small intestine.
Gut
28 Suppl
193-5
1987
Mus sp.
Suneja, SK; Ram, GC; Wagle, DS
Effects of T-2 toxin on glucose and tryptophan uptake and intestinal mucosal enzymes.
Toxicon
22
39-43
1984
Rattus
McCarthy, DM; Nicholson, JA; Kim, YS
Intestinal enzyme adaptation to normal diets of different composition.
Am J Physiol
239
G445-51
1980
Rattus
Egan-Mitchell, B; Fottrell, PF; McNicholl, B
Early or pre-coeliac mucosa: development of gluten enteropathy.
Gut
22
65-9
1981
Homo sapiens
Schwarz, SM; Heird, WC
Effects of feeding on the small intestinal mucosa of beagle pups during the first 5 d of life.
Am J Clin Nutr
60
879-86
1994
Metazoa, Canis lupus familiaris
Schmidt, W; Schneider, T; Heise, W; Schulzke, JD; Weinke, T; Ignatius, R; Owen, RL; Zeitz, M; Riecken, EO; Ullrich, R
Mucosal abnormalities in microsporidiosis.
AIDS
11
1589-94
1997
Homo sapiens
Van Biervliet, S; Eggermont, E; Carchon, H; Veereman, G; Deboeck, K
Small intestinal brush border enzymes in cystic fibrosis.
Acta Gastroenterol Belg
62
267-71
0
Homo sapiens
Meng, S; Badrinarain, J; Sibley, E; Fang, R; Hodin, R
Thyroid hormone and the d-type cyclins interact in regulating enterocyte gene transcription.
J Gastrointest Surg
5
49-55
0
Homo sapiens, Rattus, plasmids
Van Biervliet, S; Eggermont, E; Mariën, P; Hoffman, I; Veereman, G
Combined impact of mucosal damage and of cystic fibrosis on the small intestinal brush border enzyme activities.
Acta Clin Belg
58
220-4
0
Homo sapiens
Hosoyamada, T
[Clinical studies of pediatric malabsorption syndromes]
Fukuoka Igaku Zasshi
97
322-50
2006
Homo sapiens
Chopra, S; Saini, RK; Sanyal, SN
Intestinal toxicity of non-steroideal anti-inflammatory drugs with differential cyclooxigenase inhibition selectivity.
Nutr Hosp
22
528-37
0
Rattus
Prasad, KK; Thapa, BR; Nain, CK; Sharma, AK; Singh, K
Brush border enzyme activities in relation to histological lesion in pediatric celiac disease.
J Gastroenterol Hepatol
23
e348-52
2008
Homo sapiens
Park, JY; Kirn, TJ; Artis, D; Waldman, SA; Kricka, LJ
Chemiluminescence-based detection of gastrointestinal malignancies.
Luminescence
2009
Homo sapiens
Jenkins, SL; Wang, J; Vazir, M; Vela, J; Sahagun, O; Gabbay, P; Hoang, L; Diaz, RL; Aranda, R; MartÃn, MG
Role of passive and adaptive immunity in influencing enterocyte-specific gene expression.
Am J Physiol Gastrointest Liver Physiol
285
G714-25
2003
Mus sp.
Kuokkanen, M; Myllyniemi, M; Vauhkonen, M; Helske, T; Kääriäinen, I; Karesvuori, S; Linnala, A; Härkönen, M; Järvelä, I; Sipponen, P
A biopsy-based quick test in the diagnosis of duodenal hypolactasia in upper gastrointestinal endoscopy.
Endoscopy
38
708-12
2006
Homo sapiens
Raz, M; Sharon, Y; Yerushalmi, B; Birk, R
Frequency of LCT-13910C/T and LCT-22018G/A single nucleotide polymorphisms associated with adult-type hypolactasia/lactase persistence among Israelis of different ethnic groups.
Gene
519
67-70
2013
Homo sapiens
Ellestad-Sayed, JJ; Haworth, JC
Disaccharide consumption and malabsorption in Canadian Indians.
Am J Clin Nutr
30
698-703
1977
Homo sapiens
Grimmel, K; Bongartz, S; Kasper, H
Activities of intestinal enzymes in experimental chronic renal insufficiency.
Nephron
19
81-7
1977
Rattus
Fernekorn, A; Fiehring, C
[L-alanyl-L-proline-dipeptidase and glycyl-L-valine-depeptidase in malabsorption syndrome]
Z Gesamte Inn Med
31
266-9
1976
Homo sapiens
Castillo, RO; Feng, JJ; Stevenson, DK; Kwong, LK
Altered maturation of small intestinal function in the absence of intraluminal nutrients: rapid normalization with refeeding.
Am J Clin Nutr
53
558-61
1991
Rattus, Metazoa
Park, RH; Duncan, A; Russell, RI
Hypolactasia and Crohn's disease: a myth.
Am J Gastroenterol
85
708-10
1990
Homo sapiens
Langman, JM; Rowland, R
Activity of duodenal disaccharidases in relation to normal and abnormal mucosal morphology.
J Clin Pathol
43
537-40
1990
Homo sapiens
el-Lakany, S; Eagon, PK; Gavaler, JS; Schade, RR; Whiteside, T; Van Thiel, DH
Gastrointestinal function, morphology, and immune status in uremia.
Nutrition
6
461-8
0
Homo sapiens
Kovács, JB; Lörincz, M; Sashegyi, J; Marton, A; Simon, K
[Congenital saccharase-isomaltase defect--diagnostic difficulties]
Orv Hetil
130
2577-82
1989
Homo sapiens
Mobassaleh, M; Montgomery, RK; Biller, JA; Grand, RJ
Development of carbohydrate absorption in the fetus and neonate.
Pediatrics
75
160-6
1985
Homo sapiens
Pang, KY; Newman, AP; Udall, JN; Walker, WA
Development of gastrointestinal mucosal barrier. VII. In utero maturation of microvillus surface by cortisone.
Am J Physiol
249
G85-91
1985
Metazoa, Rattus
Halsted, CH; Beer, WH; Chandler, CJ; Ross, K; Wolfe, BM; Bailey, L; Cerda, JJ
Clinical studies of intestinal folate conjugases.
J Lab Clin Med
107
228-32
1986
Homo sapiens
Hampson, DJ; Kidder, DE
Influence of creep feeding and weaning on brush border enzyme activities in the piglet small intestine.
Res Vet Sci
40
24-31
1986
Suidae
Choudhury, BR; Poddar, MK
Andrographolide and kalmegh (Andrographis paniculata) extract: effect on intestinal brush-border membrane-bound hydrolases.
Methods Find Exp Clin Pharmacol
7
617-21
1985
Rattus
Horváth, K; Horn, G; Bodánszky, H; Tóth, K; Váradi, S
Disaccharidases in coeliac disease.
Acta Paediatr Hung
24
131-6
1983
Homo sapiens
Brot-Laroche, E; Alvarado, F
Disaccharide uptake by brush-border membrane vesicles lacking the corresponding hydrolases.
Biochim Biophys Acta
775
175-81
1984
Sus scrofa
McVicar, M; Mor, J; Wapnir, RA; Teichberg, S; Lifshitz, F
Jejunal transport in experimental nephrotic syndrome.
Pediatr Res
17
733-7
1983
Rattus
Potier, M; Morin, PR; Melançon, SB; Dallaire, L
Differential stabilities of fetal intestinal disaccharidases determine their relative amounts released into amniotic fluid.
Biol Neonate
45
257-60
1984
Homo sapiens
Nanthakumar, NN; Henning, SJ
Distinguishing normal and glucocorticoid-induced maturation of intestine using bromodeoxyuridine.
Am J Physiol
268
G139-45
1995
Metazoa
Keller, P; Poirée, JC; Giudicelli, J; Semenza, G
Do pancreatic proteases play a role in processing prolactase and/or in the postweaning decline of lactase?
Am J Physiol
268
G41-6
1995
Rattus, Metazoa
Mehra, R; Khambadkone, SM; Jain, MK; Ganapathy, S
Jejunal disaccharidases in protein energy malnutrition and recovery.
Indian Pediatr
31
1351-5
1994
Homo sapiens
Kelly, D; King, TP; McFadyen, M; Coutts, AG
Effect of preclosure colostrum intake on the development of the intestinal epithelium of artificially reared piglets.
Biol Neonate
64
235-44
1993
Metazoa
Yeh, KY; Yeh, M
Use of pup in a cup model to study gastrointestinal development: interaction of nutrition and pituitary hormones.
J Nutr
123
378-81
1993
Rattus
Karnak, I; Tanyel, FC; Müftüoğlu, S; Unsal, I; Cakar, N; Büyükpamukçu, N; Hiçsönmez, A
Esophageal ligation: effects on the development of fetal organic systems.
Eur J Pediatr Surg
6
328-33
1996
Oryctolagus cuniculus
Printz, H; Schlenzka, R; Requadt, P; Tscherny, M; Wagner, AC; Eissele, R; Rothmund, M; Arnold, R; Göke, B
Small bowel lengthening by mechanical distraction.
Digestion
58
240-8
1997
Oryctolagus cuniculus, Metazoa
McClure, RJ; Newell, SJ
Randomized controlled study of digestive enzyme activity following trophic feeding.
Acta Paediatr
91
292-6
2002
Homo sapiens
Simadibrata, M; Wanders, RJ; Jan, G; Tytgat, GN; Lesmana, LA; Daldiyono, ; Ariawan, I
Examination of small bowel enzymes in chronic diarrhea.
J Gastroenterol Hepatol
18
53-6
2003
Homo sapiens
Pié, S; Lallès, JP; Blazy, F; Laffitte, J; Sève, B; Oswald, IP
Weaning is associated with an upregulation of expression of inflammatory cytokines in the intestine of piglets.
J Nutr
134
641-7
2004
Sus scrofa
Chen, AC; Berhow, MA; Tappenden, KA; Donovan, SM
Genistein inhibits intestinal cell proliferation in piglets.
Pediatr Res
57
192-200
2005
Homo sapiens
Ishida, T; Kan-o, S; Mutoh, J; Takeda, S; Ishii, Y; Hashiguchi, I; Akamine, A; Yamada, H
2,3,7,8-Tetrachlorodibenzo-p-dioxin-induced change in intestinal function and pathology: evidence for the involvement of arylhydrocarbon receptor-mediated alteration of glucose transportation.
Toxicol Appl Pharmacol
205
89-97
2005
Mus sp.
Corcino, JJ; Reisenauer, AM; Halsted, CH
Jejunal Perfusion of Simple and Conjugated Folates in Tropical Sprue.
J Clin Invest
58
298-305
1976
Homo sapiens
Chauhan, A; Gupta, S; Mahmood, A
Effect of tannic acid on brush border disaccharidases in mammalian intestine.
Indian J Exp Biol
45
353-8
2007
Rattus
Lu, J; Grenache, DG
High-throughput tissue homogenization method and tissue-based quality control materials for a clinical assay of the intestinal disaccharidases.
Clin Chim Acta
411
754-7
2010
Homo sapiens, Sus scrofa
Williamson, G
Possible effects of dietary polyphenols on sugar absorption and digestion.
Mol Nutr Food Res
57
48-57
2013
Camellia sinensis, Homo sapiens, Metazoa
Liu, S; Song, M; Yun, W; Lee, J; Lee, C; Kwak, W; Han, N; Kim, H; Cho, J
Effects of oral administration of different dosages of carvacrol essential oils on intestinal barrier function in broilers.
J Anim Physiol Anim Nutr (Berl)
102
1257-1265
2018
Escherichia coli
Asp, NG; Berg, NO; Dahlqvist, A; Gudmand-Höyer, E; Jarnum, S; Mcnair, A
Intestinal disaccharidases in Greenland Eskimos.
Scand J Gastroenterol
10
513-9
1975
Homo sapiens
Asano, N; Oseki, K; Kizu, H; Matsui, K
Nitrogen-in-the-ring pyranoses and furanoses: structural basis of inhibition of mammalian glycosidases.
J Med Chem
37
3701-6
1994
Bos taurus, Rattus
Hozyasz, KK
[Promissing role of probiotics in prevention of smoking-related diseases]
Przegl Lek
65
706-8
2008
Homo sapiens
Rasmussen, TS; Koldsø, H; Nakagawa, S; Kato, A; Schiøtt, B; Jensen, HH
Synthesis of uronic-noeurostegine--a potent bacterial ?-glucuronidase inhibitor.
Org Biomol Chem
9
7807-13
2011
Rattus, Escherichia coli, Bos taurus
Campbell, BC; Molyneux, RJ; Jones, KC
Differential inhibition by castanospermine of various insect disaccharidases.
J Chem Ecol
13
1759-70
1987
Hexapoda
Gavaldà-Navarro, A; Hondares, E; Giralt, M; Mampel, T; Iglesias, R; Villarroya, F
Fibroblast growth factor 21 in breast milk controls neonatal intestine function.
Sci Rep
5
13717
2015
Homo sapiens, Rodentia, Mus sp.
Parfenov, AI; Akhmadullina, OV; Sabelnikova, EA; Belostotsky, NI; Kirova, MV; Khomeriki, SG; Bykova, SV
[Disaccharidase deficiency and functional bowel diseases].
Ter Arkh
89
45-52
2017
Homo sapiens
Ko, SR; Choi, KJ; Suzuki, K; Suzuki, Y
Enzymatic preparation of ginsenosides Rg2, Rh1, and F1.
Chem Pharm Bull (Tokyo)
51
404-8
2003
Aspergillus oryzae, Penicillium sp.
Slabý, J; Lojda, Z; Kraml, J; KolÃnská, J
Immunohistochemical localization of intestinal glycosidases.
Acta Univ Carol Med Monogr
105-11
1977
Homo sapiens, Rattus, Cavia porcellus
Duluc, I; Freund, JN; Leberquier, C; Kedinger, M
Fetal endoderm primarily holds the temporal and positional information required for mammalian intestinal development.
J Cell Biol
126
211-21
1994
Mus musculus, Mus sp., Rattus
Van Beers, EH; Einerhand, AW; Taminiau, JA; Heymans, HS; Dekker, J; Büller, HA
Pediatric duodenal biopsies: mucosal morphology and glycohydrolase expression do not change along the duodenum.
J Pediatr Gastroenterol Nutr
26
186-93
1998
Homo sapiens, Indicator
Mian, N; Anderson, CE; Kent, PW
Effect of O-sulphate groups in lactose and N-acetylneuraminyl-lactose on their enzymic hydrolysis.
Biochem J
181
387-99
1979
Escherichia coli, Rattus
Sieber, R; Stransky, M; de Vrese, M
[Lactose intolerance and consumption of milk and milk products]
Z Ernahrungswiss
36
375-93
1997
Bacteria, Homo sapiens
Obermayer-Pietsch, BM; Bonelli, CM; Walter, DE; Kuhn, RJ; Fahrleitner-Pammer, A; Berghold, A; Goessler, W; Stepan, V; Dobnig, H; Leb, G; Renner, W
Genetic predisposition for adult lactose intolerance and relation to diet, bone density, and bone fractures.
J Bone Miner Res
19
42-7
2004
Homo sapiens
Sharma, SK; Singhal, R; Malhotra, BD; Sehgal, N; Kumar, A
Lactose biosensor based on Langmuir-Blodgett films of poly(3-hexyl thiophene).
Biosens Bioelectron
20
651-7
2004
Electron
Montalto, M; Curigliano, V; Santoro, L; Vastola, M; Cammarota, G; Manna, R; Gasbarrini, A; Gasbarrini, G
Management and treatment of lactose malabsorption.
World J Gastroenterol
12
187-91
2006
Homo sapiens
Ko, SR; Suzuki, Y; Suzuki, K; Choi, KJ; Cho, BG
Marked production of ginsenosides Rd, F2, Rg3, and compound K by enzymatic method.
Chem Pharm Bull (Tokyo)
55
1522-7
2007
Aspergillus oryzae, Penicillium sp., Trichoderma viride
Stevenson, DE; Stanley, RA; Furneaux, RH
Optimization of alkyl beta-D-galactopyranoside synthesis from lactose using commercially available beta-galactosidases.
Biotechnol Bioeng
42
657-66
1993
Kluyveromyces marxianus, Kluyveromyces lactis
Perino, A; Cabras, S; Obinu, D; Cavalli Sforza, L
Lactose intolerance: a non-allergic disorder often managed by allergologists.
Eur Ann Allergy Clin Immunol
41
3-16
2009
Homo sapiens, Metazoa
Szilagyi, A; Shrier, I; Heilpern, D; Je, J; Park, S; Chong, G; Lalonde, C; Cote, LF; Lee, B
Differential impact of lactose/lactase phenotype on colonic microflora.
Can J Gastroenterol
24
373-9
2010
Enterobacteriaceae
Mackey, AD; McMahon, RJ; Townsend, JH; Gregory, JF
Uptake, hydrolysis, and metabolism of pyridoxine-5'-beta-D-glucoside in Caco-2 cells.
J Nutr
134
842-6
2004
Homo sapiens
Kaur, K; Mahmood, S; Mahmood, A
Hypolactasia as a molecular basis of lactose intolerance.
Indian J Biochem Biophys
43
267-74
2006
animal, Homo sapiens, Rodentia
Montgomery, RK; Krasinski, SD; Hirschhorn, JN; Grand, RJ
Lactose and lactase--who is lactose intolerant and why?
J Pediatr Gastroenterol Nutr
45 Suppl 2
S131-7
2007
Homo sapiens
Ugidos-Rodríguez, S; Matallana-González, MC; Sánchez-Mata, MC
Lactose malabsorption and intolerance: a review.
Food Funct
9
4056-4068
2018
Homo sapiens
Anguita-Ruiz, A; Aguilera, CM; Gil, Á
Genetics of Lactose Intolerance: An Updated Review and Online Interactive World Maps of Phenotype and Genotype Frequencies.
Nutrients
12
2020
Homo sapiens
Uchida, T; Shinohara, K; Kobayashi, K; Honda, N; Ao, T; Omata, T; Odajima, K; Koshiba, K
[Tumor markers in renal cell carcinoma]
Hinyokika Kiyo
32
929-40
1986
Homo sapiens
Metz, G; Jenkins, DJ; Peters, TJ; Newman, A; Blendis, LM
Breath hydrogen as a diagnostic method for hypolactasia.
Lancet
1
1155-7
1975
Homo sapiens
Duncombe, VM; Bolin, TD; Davis, AE; Cummins, AG; Crouch, RL
Histopathology in giardiasis: a correlation with diarrhoea.
Aust N Z J Med
8
392-6
1978
Homo sapiens
Asp, NG; Gudmand-Høyer, G; Andersen, B
Mucosal enzyme activities in the functioning intestine one and six months after jejuno-ileal by-pass operation for obesity.
Scand J Gastroenterol
14
469-73
1979
Homo sapiens
Cheng, AH; Brunser, O; Espinoza, J; Fones, HL; Monckeberg, F; Chichester, CO; Rand, G; Hourigan, AG
Long-term acceptance of low-lactose milk.
Am J Clin Nutr
32
1989-93
1979
Saccharomyces cerevisiae
Corgan, RL
Genetic counseling and parental self-concept change.
Birth Defects Orig Artic Ser
15
281-5
1979
Homo sapiens
Palitzsch, D
[Diagnosis and therapy of lactose malabsorption]
Fortschr Med
95
597-600
1977
Homo sapiens
ShershevskiÄ, MG; BeliaevskiÄ, AA; NishchiÄ, VA; Fomina, TI
[Assessment of the lactose test and its value in detecting intolerance to milk sugar]
Vopr Pitan
36-40
0
Indicator
Adlung, J; Kelch, L; Pancho, W; Grazikowske, H; Uthgenannt, H
[14CO2 exhalation tests. Diagnostic improvement in gastroenterologic diseases]
Z Gastroenterol
14
565-73
1976
Homo sapiens
Paige, DM; Bayless, TM; Dellinger, WS
Relationship of milk consumption to blood glucose rise in lactose intolerant individuals.
Am J Clin Nutr
28
677-80
1975
Homo sapiens
Yoshida, Y; Sasaki, G; Goto, S; Yanagiya, S; Takashina, K
Studies on the etiology of milk intolerance in Japanese adults.
Gastroenterol Jpn
10
29-34
1975
Metazoa
Freiburghaus, AU; Schmitz, J; Schindler, M; Rotthauwe, HW; Kuitunen, P; Launiala, K; Hadorn, B
Protein patterns of brush-border fragments in congenital lactose malabsorption and in specific hypolactasia of the adult.
N Engl J Med
294
1030-2
1976
Homo sapiens
Brookfield, DS; McCandless, AE; Smith, CS
Thyrotoxicosis in a neonate of a mother with no history of thyroid disease.
Arch Dis Child
51
314-6
1976
Homo sapiens
ChopeÄ, IV
[The use of parietal pH-metry in the diagnosis of intestinal diseases]
Lab Delo
21-4
1990
Homo sapiens
Alessandri, JM; Guesnet, P; Arfi, TS; Durand, G
Changes in fatty acid composition during cell differentiation in the small intestine of suckling piglets.
Biochim Biophys Acta
1086
340-8
1991
Homo sapiens
Ladas, SD; Katsiyiannaki-Latoufi, E; Raptis, SA
Lactose maldigestion and milk intolerance in healthy Greek schoolchildren.
Am J Clin Nutr
53
676-80
1991
Homo sapiens
Perman, JA
Clinical application of breath hydrogen measurements.
Can J Physiol Pharmacol
69
111-5
1991
Homo sapiens, Indicator
Hiele, M
Georges Brohee Prize 1988-1989. Assimilation of nutritional carbohydrates: influence of hydrolysis.
Acta Gastroenterol Belg
54
3-11
0
Homo sapiens
Gendrel, D; Richard-Lenoble, D; Kombila, M; Dupont, C; Gendrel, C; Nardou, M; Chaussain, M
[Intestinal parasites and lactose malabsorption]
Arch Fr Pediatr
47
577-80
1990
Giardia, Homo sapiens
Lobley, RW; Burrows, PC; Warwick, R; Dawson, DJ; Holmes, R
Simultaneous assessment of intestinal permeability and lactose tolerance with orally administered raffinose, lactose and L-arabinose.
Clin Sci (Lond)
79
175-83
1990
Homo sapiens
Griessen, M; Cochet, B; Infante, F; Jung, A; Bartholdi, P; Donath, A; Loizeau, E; Courvoisier, B
Calcium absorption from milk in lactase-deficient subjects.
Am J Clin Nutr
49
377-84
1989
Homo sapiens
Bhatnagar, R; Sharma, YR; Vajpayee, RB; Madan, M; Chhabra, VK; Ram, N; Mukesh, K; Azad, RV; Sharma, R
Does milk have a cataractogenic effect? Weighing of clinical evidence.
Dig Dis Sci
34
1745-50
1989
Areas
Savaiano, DA; Kotz, C
Recent advances in the management of lactose intolerance.
Bol Asoc Med P R
81
188-92
1989
Bacteria
Kien, CL; Heitlinger, LA; Li, BU; Murray, RD
Digestion, absorption, and fermentation of carbohydrates.
Semin Perinatol
13
78-87
1989
Homo sapiens
Hildebrandt, J; Lauschke, G; Wolff, H; Herrmann, U
[Selective proximal vagotomy with and without pyloroplasty--results of a randomized clinical study of duodenal ulcer 5 and 8 years after surgery]
Zentralbl Chir
113
827-36
1988
Swinepox virus (STRAIN KASZA)
Ståhlberg, MR; Savilahti, E
Infantile colic and feeding.
Arch Dis Child
61
1232-3
1986
Homo sapiens
Becciolini, A; Giachè, V; Scubla, E; D'Abbondio, D
Circadian phenomena and irradiation. Modifications of enzyme activity in the small intestine after sublethal exposure.
Acta Oncol
26
477-81
1987
Metazoa
Segal, I
The geography of chronic digestive disease in southern Africa.
S Afr Med J
73
649-52
1988
Pierinae
Scrimshaw, NS; Murray, EB
The acceptability of milk and milk products in populations with a high prevalence of lactose intolerance.
Am J Clin Nutr
48
1079-159
1988
Homo sapiens, Mammalia
Scrimshaw, NS; Murray, E
[Lactose tolerance and milk consumption: myths and realities]
Arch Latinoam Nutr
38
543-67
1988
Bacteria, animal
Lisker, R; Cervantes, G; Pérez-Briceño, R; Alva, G
Lack of relationship between lactose absorption and senile cataracts.
Ann Ophthalmol
20
436-8
1988
Homo sapiens
Beer, WH; Fan, A; Halsted, CH
Clinical and nutritional implications of radiation enteritis.
Am J Clin Nutr
41
85-91
1985
Homo sapiens
Zaniboni, MG; Lambertini, A; Romeo, N; Albini, P; Pozzi, M
[Usefulness of the integration between the values of the 1-hour blood xylose test and the hydrogen breath-test after xylose oral load for the indirect evaluation of mucosa damage]
Pediatr Med Chir
7
243-7
0
Homo sapiens
Savaiano, DA; AbouElAnouar, A; Smith, DE; Levitt, MD
Lactose malabsorption from yogurt, pasteurized yogurt, sweet acidophilus milk, and cultured milk in lactase-deficient individuals.
Am J Clin Nutr
40
1219-23
1984
Areas
Nagy, L; Mózsik, G; Garamszegi, M; Sasréti, E; Ruzsa, C; Jávor, T
Lactose-poor milk in adult lactose intolerance.
Acta Med Hung
40
239-45
1983
Homo sapiens
Nesheim, MC
Some experimental approaches to the study of nutrition and parasitic infection.
Fed Proc
43
235-8
1984
Ascaris, Suidae
Bolin, TD
Use of oral sodium cromoglycate in persistent diarrhoea.
Gut
21
848-50
1980
Homo sapiens
Bergoz, R; Griessen, M; Infante, F; de Peyer, R; Vallotton, MC
Significance of duodenal disaccharidases. A comparative study of duodenal and jejunal values.
Digestion
22
108-12
1981
Homo sapiens
Levin, RJ
Assessing small intestinal function in health and disease in vivo and in vitro.
Scand J Gastroenterol Suppl
74
31-51
1982
Homo sapiens
Brand, JC; Gracey, MS; Spargo, RM; Dutton, SP
Lactose malabsorption in Australian Aborigines.
Am J Clin Nutr
37
449-52
1983
Homo sapiens
Bolin, TD; Davis, AE; Duncombe, VM
A prospective study of persistent diarrhoea.
Aust N Z J Med
12
22-6
1982
Homo sapiens
Mir, GN; Alioto, RL
A semichronic diarrheal model.
J Pharmacol Methods
7
115-20
1982
Rattus
Kuitunen, P; Kosnai, I; Savilahti, E
Morphometric study of the jejunal mucosa in various childhood enteropathies with special reference to intraepithelial lymphocytes.
J Pediatr Gastroenterol Nutr
1
525-31
1982
Homo sapiens
Di Lorenzo, M; Bass, J; Krantis, A
An intraluminal model of necrotizing enterocolitis in the developing neonatal piglet.
J Pediatr Surg
30
1138-42
1995
Bacteria, Homo sapiens
Herrinton, LJ; Weiss, NS; Beresford, SA; Stanford, JL; Wolfla, DM; Feng, Z; Scott, CR
Lactose and galactose intake and metabolism in relation to the risk of epithelial ovarian cancer.
Am J Epidemiol
141
407-16
1995
Homo sapiens
Auricchio, S; Maiuri, L
Cellular basis of adult-type hypolactasia.
Acta Paediatr Suppl
83
14-7
1994
Homo sapiens, Oryctolagus cuniculus, Rattus
Villako, K; Maaroos, H
Clinical picture of hypolactasia and lactose intolerance.
Scand J Gastroenterol Suppl
202
36-54
1994
Homo sapiens
Tamm, A
Management of lactose intolerance.
Scand J Gastroenterol Suppl
202
55-63
1994
Homo sapiens
Sahi, T
Genetics and epidemiology of adult-type hypolactasia.
Scand J Gastroenterol Suppl
202
7-20
1994
Homo sapiens, Mammalia
Parnes, HL; Fung, E; Schiffer, CA
Chemotherapy-induced lactose intolerance in adults.
Cancer
74
1629-33
1994
Bacteria, Homo sapiens
Klauser, AG; Voderholzer, WA; Knesewitsch, PA; Schindlbeck, NE; Müller-Lissner, SA
What is behind dyspepsia?
Dig Dis Sci
38
147-54
1993
Homo sapiens
Olchowy, TW; Linnabary, RD; Andrews, FM; Longshore, RC
Lactose intolerance in a calf.
J Vet Intern Med
7
12-5
0
Homo sapiens, Metazoa
Zancan, L; Guariso, G; Gobber, D
[Abdominal pain syndrome recurring after 40 years: critical revision]
Pediatr Med Chir
18
65-6
0
Helicobacter pylori
Sanders, ME; Walker, DC; Walker, KM; Aoyama, K; Klaenhammer, TR
Performance of commercial cultures in fluid milk applications.
J Dairy Sci
79
943-55
1996
Streptococcus thermophilus, Bacteria, Lactobacillus acidophilus, Bifidobacterium
Weglage, J; Weber, P; Fliedner, M; Grohmann, J; Zass, R; Rossi, R
[Abuse of artificial sweetener as differential diagnosis of lactose intolerance]
Klin Padiatr
208
17-8
0
Homo sapiens
Teesalu, S; Vihalemm, T; Vaasa, IO
Nutrition in prevention of osteoporosis.
Scand J Rheumatol Suppl
103
81-2; discussion 83
1996
Homo sapiens
Valenkevich, LN; Iakhontova, OI; Shubina, ME
[Use of enzyme substitutes in hypolactasia]
Klin Med (Mosk)
74
46-8
1996
Homo sapiens
Solomons, NW
[Lactose and its implications in gastroenterology. Nutrition and food sciences]
Rev Invest Clin
48 Suppl
1-13
1996
Homo sapiens, Mammalia
Uribe-Esquivel, M; Moran, S; Poo, JL; Muñoz, RM
In vitro and in vivo lactose and lactulose effects on colonic fermentation and portal-systemic encephalopathy parameters.
Scand J Gastroenterol Suppl
222
49-52
1997
Homo sapiens
Burrin, DG
Is milk-borne insulin-like growth factor-I essential for neonatal development?
J Nutr
127
975S-979S
1997
Metazoa
Baldrick, P; Bamford, DG
A toxicological review of lactose to support clinical administration by inhalation.
Food Chem Toxicol
35
719-33
1997
Homo sapiens
McBean, LD; Miller, GD
Allaying fears and fallacies about lactose intolerance.
J Am Diet Assoc
98
671-6
1998
Homo sapiens
Koskenpato, J; Kairemo, K; Korppi-Tommola, T; Färkkilä, M
Role of gastric emptying in functional dyspepsia: a scintigraphic study of 94 subjects.
Dig Dis Sci
43
1154-8
1998
Helicobacter pylori, Homo sapiens
Srinivasan, R; Minocha, A
When to suspect lactose intolerance. Symptomatic, ethnic, and laboratory clues.
Postgrad Med
104
109-11, 115-6, 122-3
1998
Homo sapiens
Karcher, RE; Truding, RM; Stawick, LE
Using a cutoff of <10 ppm for breath hydrogen testing: a review of five years' experience.
Ann Clin Lab Sci
29
1-8
0
Homo sapiens
Guéguen, L; Pointillart, A
The bioavailability of dietary calcium.
J Am Coll Nutr
19
119S-136S
2000
Homo sapiens, animal
Gutzwiller, A
Glucose and galactose absorption after ingestion of milk containing hydrolysed lactose in calves with diarrhoea.
J Vet Med A Physiol Pathol Clin Med
47
495-500
2000
Cryptosporidium, Rotavirus, Metazoa, Alphacoronavirus
Buzaid, AC; Anderson, CM
The changing prognosis of melanoma.
Curr Oncol Rep
2
322-8
2000
Homo sapiens
Ko, SR; Suzuki, Y; Choi, KJ; Kim, YH
Enzymatic preparation of genuine prosapogenin, 20(S)-ginsenoside Rh1, from ginsenosides Re and Rg1.
Biosci Biotechnol Biochem
64
2739-43
2000
Panax ginseng, Penicillium sp.
Kuchkareva, LS; Rakhimov, KR
[Mother thyroid status and development of enzymes of initial and final phases of carbohydrate hydrolysis]
Ross Fiziol Zh Im I M Sechenova
87
995-1002
2001
Rattus
Di Stefano, M; Veneto, G; Malservisi, S; Strocchi, A; Corazza, GR
Lactose malabsorption and intolerance in the elderly.
Scand J Gastroenterol
36
1274-8
2001
Homo sapiens, Rattus
Favre, A; Szylit, O; Popot, F; Catala, I; Rondeau, C; Maurage, C; Gold, F; Borderon, JC; Butel, MJ
Diet, length of gestation, and fecal short chain fatty acids in healthy premature neonates.
JPEN J Parenter Enteral Nutr
26
51-6
0
Homo sapiens
Swagerty, DL; Walling, AD; Klein, RM
Lactose intolerance.
Am Fam Physician
65
1845-50
2002
Homo sapiens
Butel, MJ; Waligora-Dupriet, AJ; Szylit, O
Oligofructose and experimental model of neonatal necrotising enterocolitis.
Br J Nutr
87 Suppl 2
S213-9
2002
Bacteria, Clostridia
Buckley, M
Some new and important clues to the causes of colic.
Br J Community Nurs
5
462, 464-5
2000
Homo sapiens
Vilotte, JL
Lowering the milk lactose content in vivo: potential interests, strategies and physiological consequences.
Reprod Nutr Dev
42
127-32
0
Homo sapiens, Mammalia, Mus musculus
Solomons, NW
Fermentation, fermented foods and lactose intolerance.
Eur J Clin Nutr
56 Suppl 4
S50-5
2002
Homo sapiens
Hessels, J; Eidhof, HH; Steggink, J; Roeloffzen, WW; Wu, K; Tan, G; van de Stadt, J; van Bergeijk, L
Assessment of hypolactasia and site-specific intestinal permeability by differential sugar absorption of raffinose, lactose, sucrose and mannitol.
Clin Chem Lab Med
41
1056-63
2003
Homo sapiens
Thomas, C; Oates, PS
Ferroportin/IREG-1/MTP-1/SLC40A1 modulates the uptake of iron at the apical membrane of enterocytes.
Gut
53
44-9
2004
Rattus
Szilagyi, A
Redefining lactose as a conditional prebiotic.
Can J Gastroenterol
18
163-7
2004
Homo sapiens
Simakachorn, N; Tongpenyai, Y; Tongtan, O; Varavithya, W
Randomized, double-blind clinical trial of a lactose-free and a lactose-containing formula in dietary management of acute childhood diarrhea.
J Med Assoc Thai
87
641-9
2004
Homo sapiens, Rotavirus
Sibley, E
Genetic variation and lactose intolerance: detection methods and clinical implications.
Am J Pharmacogenomics
4
239-45
2004
Homo sapiens
Brown, AC; Valiere, A
Probiotics and medical nutrition therapy.
Nutr Clin Care
7
56-68
0
Helicobacter pylori, Homo sapiens
Enattah, NS; Sulkava, R; Halonen, P; Kontula, K; Järvelä, I
Genetic variant of lactase-persistent C/T-13910 is associated with bone fractures in very old age.
J Am Geriatr Soc
53
79-82
2005
Homo sapiens
Myles, S; Bouzekri, N; Haverfield, E; Cherkaoui, M; Dugoujon, JM; Ward, R
Genetic evidence in support of a shared Eurasian-North African dairying origin.
Hum Genet
117
34-42
2005
Homo sapiens
Rasinperä, H; Forsblom, C; Enattah, NS; Halonen, P; Salo, K; Victorzon, M; Mecklin, JP; Järvinen, H; Enholm, S; Sellick, G; Alazzouzi, H; Houlston, R; Robinson, J; Groop, PH; Tomlinson, I; Schwartz, S; Aaltonen, LA; Järvelä, I; ,
The C/C-13910 genotype of adult-type hypolactasia is associated with an increased risk of colorectal cancer in the Finnish population.
Gut
54
643-7
2005
Homo sapiens
Cottrell, JJ; Stoll, B; Buddington, RK; Stephens, JE; Cui, L; Chang, X; Burrin, DG
Glucagon-like peptide-2 protects against TPN-induced intestinal hexose malabsorption in enterally refed piglets.
Am J Physiol Gastrointest Liver Physiol
290
G293-300
2006
Homo sapiens, Suidae
Campbell, AK; Waud, JP; Matthews, SB
The molecular basis of lactose intolerance.
Sci Prog
88
157-202
2005
Mammalia, Bacteria, Homo sapiens
Szilagyi, A; Nathwani, U; Vinokuroff, C; Correa, JA; Shrier, I
The effect of lactose maldigestion on the relationship between dairy food intake and colorectal cancer: a systematic review.
Nutr Cancer
55
141-50
2006
Areas
Borinskaia, SA; Rebrikova, DV; Nefedova, VV; Kofiadi, IA; Sokolova, MV; Kolchina, EV; Kulikova, EA; Chernyshov, VN; Kutsev, SI; Polonikov, AV; Ivanov, VP; Kozlov, AI; IankovskiÄ, NK
[Molecular diagnosis and frequencies of primary hypolactasia in populations of RUSSIA and neighboring countries]
Mol Biol (Mosk)
40
1031-6
0
Homo sapiens
Liew, M; Seipp, M; Durtschi, J; Margraf, RL; Dames, S; Erali, M; Voelkerding, K; Wittwer, C
Closed-tube SNP genotyping without labeled probes/a comparison between unlabeled probe and amplicon melting.
Am J Clin Pathol
127
341-8
2007
Homo sapiens
Schirru, E; Corona, V; Usai-Satta, P; Scarpa, M; Oppia, F; Loriga, F; Cucca, F; De Virgiliis, S; Rossino, R; Macis, MD; Jores, RD; Congia, M
Genetic testing improves the diagnosis of adult type hypolactasia in the Mediterranean population of Sardinia.
Eur J Clin Nutr
61
1220-5
2007
Homo sapiens
Burger, J; Kirchner, M; Bramanti, B; Haak, W; Thomas, MG
Absence of the lactase-persistence-associated allele in early Neolithic Europeans.
Proc Natl Acad Sci U S A
104
3736-41
2007
Homo sapiens
Kerber, M; Oberkanins, C; Kriegshäuser, G; Kollerits, B; Dossenbach-Glaninger, A; Fuchs, D; Ledochowski, M
Hydrogen breath testing versus LCT genotyping for the diagnosis of lactose intolerance: a matter of age?
Clin Chim Acta
383
91-6
2007
Homo sapiens, Indicator
Ojetti, V; La Mura, R; Zocco, MA; Cesaro, P; De Masi, E; La Mazza, A; Cammarota, G; Gasbarrini, G; Gasbarrini, A
Quick test: a new test for the diagnosis of duodenal hypolactasia.
Dig Dis Sci
53
1589-92
2008
Homo sapiens
Lomer, MC; Parkes, GC; Sanderson, JD
Review article: lactose intolerance in clinical practice--myths and realities.
Aliment Pharmacol Ther
27
93-103
2008
Homo sapiens
Tag, CG; Oberkanins, C; Kriegshäuser, G; Ingram, CJ; Swallow, DM; Gressner, AM; Ledochowski, M; Weiskirchen, R
Evaluation of a novel reverse-hybridization StripAssay for typing DNA variants useful in diagnosis of adult-type hypolactasia.
Clin Chim Acta
392
58-62
2008
Homo sapiens
Hauser, H; Zach, O; Krieger, O; Kasparu, H; Koenig, J; Girschikofsky, M; Oberbauer, R; Lutz, D
A single nucleotide polymorphism at chromosome 2q21.3 (LCT -13910C>T) associates with clinical outcome after allogeneic hematopoietic stem cell transplantation.
Blood
112
2156-9
2008
Homo sapiens
Krawczyk, M; Wolska, M; Schwartz, S; Gruenhage, F; Terjung, B; Portincasa, P; Sauerbruch, T; Lammert, F
Concordance of genetic and breath tests for lactose intolerance in a tertiary referral centre.
J Gastrointestin Liver Dis
17
135-9
2008
Homo sapiens
Mottes, M; Belpinati, F; Milani, M; Saccomandi, D; Petrelli, E; Calacoci, M; Chierici, R; Pignatti, PF; Borgna-Pignatti, C
Genetic testing for adult-type hypolactasia in Italian families.
Clin Chem Lab Med
46
980-4
2008
Homo sapiens
Seppo, L; Tuure, T; Korpela, R; Järvelä, I; Rasinperä, H; Sahi, T
Can primary hypolactasia manifest itself after the age of 20 years? A two-decade follow-up study.
Scand J Gastroenterol
43
1082-7
2008
Homo sapiens
Montalto, M; Gallo, A; Santoro, L; D'Onofrio, F; Curigliano, V; Covino, M; Cammarota, G; Grieco, A; Gasbarrini, A; Gasbarrini, G
Low-dose lactose in drugs neither increases breath hydrogen excretion nor causes gastrointestinal symptoms.
Aliment Pharmacol Ther
28
1003-12
2008
Homo sapiens
Jørgensen, MK; Thode, J; Davidsen, B; Gerner, C; Bathum, L
[Diagnosing lactose intolerance in adults.]
Ugeskr Laeger
170
3309-3312
2008
Homo sapiens
Kull, M; Kallikorm, R; Lember, M
Impact of molecularly defined hypolactasia, self-perceived milk intolerance and milk consumption on bone mineral density in a population sample in Northern Europe.
Scand J Gastroenterol
44
415-21
2009
Homo sapiens
Nagy, D; Bogácsi-Szabó, E; Várkonyi, A; Csányi, B; Czibula, A; Bede, O; Tari, B; Raskó, I
Prevalence of adult-type hypolactasia as diagnosed with genetic and lactose hydrogen breath tests in Hungarians.
Eur J Clin Nutr
2009
Homo sapiens
Achaz, G
Frequency spectrum neutrality tests: one for all and all for one.
Genetics
183
249-58
2009
Homo sapiens
Mattar, R; Monteiro, MS; Villares, CA; Santos, AF; Silva, JM; Carrilho, FJ
Frequency of LCT -13910C>T single nucleotide polymorphism associated with adult-type hypolactasia/lactase persistence among Brazilians of different ethnic groups.
Nutr J
8
46
2009
Homo sapiens
Szilagyi, A; Shrier, I; Chong, G; Je, JS; Park, S; Heilpern, D; Lalonde, C; Cote, L; Lee, B
Lack of effect of lactose digestion status on baseline fecal micoflora.
Can J Gastroenterol
23
753-9
2009
Bacteria, Transformation
Campbell, AK; Waud, JP; Matthews, SB
The molecular basis of lactose intolerance.
Sci Prog
92
241-87
2009
Bacteria, Homo sapiens, Mammalia
Alfonso-Sánchez, MA; Pérez-Miranda, AM; GarcÃa-Obregón, S; Peña, JA
An evolutionary approach to the high frequency of the Delta F508 CFTR mutation in European populations.
Med Hypotheses
74
989-92
2010
Bos taurus
Tarabra, E; Pazienza, P; Borghesio, E; Actis, GC; Tappero, G; Framarin, L; Ayoubi, M; Castellino, F; Leone, N; Sansoè, G; De Paolis, P; Comandone, A; Rosina, F
LCT-13910C>T polymorphism-associated lactose malabsorption and risk for colorectal cancer in Italy.
Dig Liver Dis
2010
Homo sapiens
Agueda, L; Urreizti, R; Bustamante, M; Jurado, S; Garcia-Giralt, N; DÃez-Pérez, A; Nogués, X; Mellibovsky, L; Grinberg, D; Balcells, S
Analysis of Three Functional Polymorphisms in Relation to Osteoporosis Phenotypes: Replication in a Spanish Cohort.
Calcif Tissue Int
2010
Homo sapiens
Juste, RA
Crohn's disease and ruminant farming. Got lactase?
Med Hypotheses
75
7-13
2010
Homo sapiens, Mycobacterium avium subsp. paratuberculosis, Equus caballus, Bos taurus, animal
Szilagyi, A
Determinants of geographic patterns of diseases: interaction of lactose/lactase status and sunshine exposure.
Med Hypotheses
75
466-70
2010
Notolabrus celidotus, Areas
Mattar, R; Mazo, DF
[Lactose intolerance: changing paradigms due to molecular biology]
Rev Assoc Med Bras
56
230-6
0
Mammalia
Corella, D; Arregui, M; Coltell, O; Portolés, O; Guillem-Sáiz, P; Carrasco, P; Sorlí, JV; Ortega-Azorín, C; González, JI; Ordovás, JM
Association of the LCT-13910C>T Polymorphism With Obesity and Its Modulation by Dairy Products in a Mediterranean Population.
Obesity (Silver Spring)
2010
Homo sapiens
Hall, B; Chesters, J; Robinson, A
Infantile colic: A systematic review of medical and conventional therapies.
J Paediatr Child Health
2011
Homo sapiens
Eadala, P; Matthews, SB; Waud, JP; Green, JT; Campbell, AK
Association of lactose sensitivity with inflammatory bowel disease - demonstrated by analysis of genetic polymorphism, breath gases and symptoms.
Aliment Pharmacol Ther
2011
Homo sapiens, Archaea
Shimoda, K; Kubota, N
Chemo-enzymatic synthesis of ester-linked docetaxel-monosaccharide conjugates as water-soluble prodrugs.
Molecules
16
6769-77
2011
Homo sapiens
Takagi, T; Kondo, T; Iizuka, J; Tomita, E; Kobayashi, H; Hashimoto, Y; Tanabe, K
Predictors for postoperative renal function after open partial nephrectomy: Including postoperative biomarkers.
Int J Urol
19
823-8
2012
Homo sapiens
Raska, P; Iversen, E; Chen, A; Chen, Z; Fridley, BL; Permuth-Wey, J; Tsai, YY; Vierkant, RA; Goode, EL; Risch, H; Schildkraut, JM; Sellers, TA; Barnholtz-Sloan, J
European American stratification in ovarian cancer case control data: the utility of genome-wide data for inferring ancestry.
PLoS One
7
e35235
2012
Homo sapiens
Vuorisalo, T; Arjamaa, O; Vasemägi, A; Taavitsainen, JP; Tourunen, A; Saloniemi, I
High lactose tolerance in North Europeans: a result of migration, not in situ milk consumption.
Perspect Biol Med
55
163-74
2012
Homo sapiens, Bos taurus
Dunne, J; Evershed, RP; Salque, M; Cramp, L; Bruni, S; Ryan, K; Biagetti, S; di Lernia, S
First dairying in green Saharan Africa in the fifth millennium BC.
Nature
486
390-4
2012
Homo sapiens, Bos taurus, Capra hircus, Ovis aries, animal
Tarner, IH; Erkal, MZ; Obermayer-Pietsch, BM; Hofbauer, LC; Bergmann, S; Goettsch, C; Madlener, K; Müller-Ladner, U; Lange, U
Osteometabolic and Osteogenetic Pattern of Turkish Immigrants in Germany.
Exp Clin Endocrinol Diabetes
2012
Homo sapiens
Bian, X; Wang, Q; Ke, C; Zhao, G; Li, Y
A new series of N2-substituted-5-(p-toluenesulfonylamino)phthalimide analogues as ?-glucosidase inhibitors.
Bioorg Med Chem Lett
23
2022-6
2013
Rattus
Brüssow, H
Nutrition, population growth and disease: a short history of lactose.
Environ Microbiol
15
2154-61
2013
Bacteria, Bos taurus, Escherichia coli, Homo sapiens, Mammalia, Rotavirus
Aragón, JJ; Hermida, C; Martínez-Costa, OH; Sánchez, V; Martín, I; Sánchez, JJ; Codoceo, R; Cano, JM; Cano, A; Crespo, L; Torres, Y; García, FJ; Fernández-Mayoralas, A; Solera, J; Martínez, P
Noninvasive Diagnosis of Hypolactasia With 4-Galactosylxylose: A Multicentre, Open-Label, Phase IIB-III Nonrandomized Trial.
J Clin Gastroenterol
2013
Homo sapiens
Liu, X; Ong, RT; Pillai, EN; Elzein, AM; Small, KS; Clark, TG; Kwiatkowski, DP; Teo, YY
Detecting and Characterizing Genomic Signatures of Positive Selection in Global Populations.
Am J Hum Genet
2013
Homo sapiens
Savaiano, DA
Lactose digestion from yogurt: mechanism and relevance.
Am J Clin Nutr
2014
Streptococcus thermophilus, Lactobacillus acidophilus, Lactobacillus delbrueckii subsp. bulgaricus, Homo sapiens, Bacteria
Liu, F; Rainosek, SW; Sadovova, N; Fogle, CM; Patterson, TA; Hanig, JP; Paule, MG; Slikker, W; Wang, C
Protective effect of acetyl-l-carnitine on propofol-induced toxicity in embryonic neural stem cells.
Neurotoxicology
2014
Rattus
Enko, D; Rezanka, E; Stolba, R; Halwachs-Baumann, G
Lactose malabsorption testing in daily clinical practice: a critical retrospective analysis and comparison of the hydrogen/methane breath test and genetic test (c/t-13910 polymorphism) results.
Gastroenterol Res Pract
2014
464382
2014
Homo sapiens
Hodgson, JA; Mulligan, CJ; Al-Meeri, A; Raaum, RL
Early back-to-Africa migration into the Horn of Africa.
PLoS Genet
10
e1004393
2014
Arabia
Omenn, GS
Enhancing the Teaching of Evolution in Public Health.
Evolution (N Y)
4
567-573
2011
Homo sapiens, Bos taurus, Ovis aries
Estévez, CA; Isasi, JR; Larrañeta, E; Vélaz, I
Release of ?-galactosidase from poloxamine/?-cyclodextrin hydrogels.
Beilstein J Org Chem
10
3127-35
2014
Mammalia
Szilagyi, A
Adult lactose digestion status and effects on disease.
Can J Gastroenterol Hepatol
29
149-56
2015
Homo sapiens
Ma, Y; Ding, X; Qanbari, S; Weigend, S; Zhang, Q; Simianer, H
Properties of different selection signature statistics and a new strategy for combining them.
Heredity (Edinb)
115
426-36
2015
Homo sapiens
Gawde, SR; Patel, TC; Rege, NN; Gajbhiye, S; Uchil, D
Evaluation of effects of Ma??urabhasma on structural and functional integrity of small intestine in comparison with ferrous sulfate using an experimental model of iron deficiency anemia.
Anc Sci Life
34
134-41
0
Rattus
Houben, E; De Preter, V; Billen, J; Van Ranst, M; Verbeke, K
Additional Value of CH? Measurement in a Combined (13)C/H? Lactose Malabsorption Breath Test: A Retrospective Analysis.
Nutrients
7
7469-85
2015
Homo sapiens
Deng, Y; Misselwitz, B; Dai, N; Fox, M
Lactose Intolerance in Adults: Biological Mechanism and Dietary Management.
Nutrients
7
8020-35
2015
Homo sapiens
Buzás, GM
[Lactose intolerance: past and present. Part II].
Orv Hetil
156
1741-9
2015
Homo sapiens
Buzás, GM
[Lactose intolerance: past and present. Part 1].
Orv Hetil
156
1532-9
2015
Homo sapiens
Podgorná, E; Diallo, I; Vangenot, C; Sanchez-Mazas, A; Sabbagh, A; ?erný, V; Poloni, ES
Variation in NAT2 acetylation phenotypes is associated with differences in food-producing subsistence modes and ecoregions in Africa.
BMC Evol Biol
15
263
2015
Homo sapiens
Lukito, W; Malik, SG; Surono, IS; Wahlqvist, ML
From 'lactose intolerance' to 'lactose nutrition'.
Asia Pac J Clin Nutr
24 Suppl 1
S1-8
2015
Homo sapiens
Lee, MS; Wahlqvist, ML; Peng, CJ
Dairy foods and health in Asians: Taiwanese considerations.
Asia Pac J Clin Nutr
24 Suppl 1
S14-20
2015
Coffea
Vandenplas, Y
Lactose intolerance.
Asia Pac J Clin Nutr
24 Suppl 1
S9-13
2015
Homo sapiens
Zhou, Q; Zhao, L; Guan, Y
Strong Selection at MHC in Mexicans since Admixture.
PLoS Genet
12
e1005847
2016
Homo sapiens
Liu, J; Chang, J; Yao, A; Hu, Y; Yuan, Y; Yu, F; Ma, Z; Wang, G; Zhao, X
Diagnosis and clinical observation of lactose-free milk powder on treatment of neonatal diarrhea.
Pak J Pharm Sci
29
309-14
2016
Bos taurus
Uribe-Esquivel, M; Moran V, S; Poo, JL; Muñoz, RM
In Vitro and In Vivo Lactose and Lactulose Effects on Colonic Fermentation and Portal-systemic Encephalopathy Parameters.
Scand J Gastroenterol
32 Suppl 222
49-52
1997
Homo sapiens
de Campos Mazo, DF; Mattar, R; Stefano, JT; da Silva-Etto, JM; Diniz, MA; Duarte, SM; Rabelo, F; Lima, RV; de Campos, PB; Carrilho, FJ; Oliveira, CP
Hypolactasia is associated with insulin resistance in nonalcoholic steatohepatitis.
World J Hepatol
8
1019-1027
2016
Homo sapiens
Esposito, T; Lobaccaro, JM; Esposito, MG; Monda, V; Messina, A; Paolisso, G; Varriale, B; Monda, M; Messina, G
Effects of low-carbohydrate diet therapy in overweight subjects with autoimmune thyroiditis: possible synergism with ChREBP.
Drug Des Devel Ther
10
2939-2946
2016
Homo sapiens
Vandenplas, Y; Bacarea, A; Marusteri, M; Bacarea, V; Constantin, M; Manolache, M
Efficacy and safety of APT198K for the treatment of infantile colic: a pilot study.
J Comp Eff Res
6
137-144
2017
Limosilactobacillus reuteri, Bifidobacterium, Homo sapiens
Delacour, H; Leduc, A; Louçano-Perdriat, A; Plantamura, J; Ceppa, F
Diagnosis of genetic predisposition for lactose intolerance by high resolution melting analysis.
Ann Biol Clin (Paris)
75
67-74
2017
Mammalia
Comerford, KB; Pasin, G
Gene-Dairy Food Interactions and Health Outcomes: A Review of Nutrigenetic Studies.
Nutrients
9
2017
Homo sapiens
Storhaug, CL; Fosse, SK; Fadnes, LT
Country, regional, and global estimates for lactose malabsorption in adults: a systematic review and meta-analysis.
Lancet Gastroenterol Hepatol
2
738-746
2017
Homo sapiens
Enko, D; Wagner, H; Kriegshäuser, G; Brandmayr, W; Halwachs-Baumann, G; Schnedl, WJ; Zelzer, S; Mangge, H; Meinitzer, A
Assessment of tryptophan metabolism and signs of depression in individuals with carbohydrate malabsorption.
Psychiatry Res
262
595-599
2018
Homo sapiens
Lebeer, S; Bron, PA; Marco, ML; Van Pijkeren, JP; O'Connell Motherway, M; Hill, C; Pot, B; Roos, S; Klaenhammer, T
Identification of probiotic effector molecules: present state and future perspectives.
Curr Opin Biotechnol
49
217-223
2018
Lactobacillus, Bifidobacterium
Gençdal, G; Salman, E; Özütemiz, Ö; Akarca, US
Association of LCT-13910 C/T Polymorphism and Colorectal Cancer.
Ann Coloproctol
33
169-172
2017
Homo sapiens, Indicator
Wortmann, AC; Simon, D; Mazzoleni, LE; Sander, GB; Francesconi, CFM; Nabinger, DD; Grott, CS; Rech, TF; Mazzoleni, F; Lunge, VR; Bona, LR; Milbradt, TC; Silveira, TRD
The association between adult-type hypolactasia and symptoms of functional dyspepsia.
Genet Mol Biol
2018
Homo sapiens
Oak, SJ; Jha, R
The effects of probiotics in lactose intolerance: A systematic review.
Crit Rev Food Sci Nutr
1-9
2018
Homo sapiens
Takajo, I; Umekita, K; Ikei, Y; Oshima, K; Okayama, A
Adult T-cell Leukemia/Lymphoma as a Methotrexate-associated Lymphoproliferative Disorder in a Patient with Rheumatoid Arthritis - A Case Report.
Intern Med
2018
Homo sapiens
James, WPT
From Treating Childhood Malnutrition to Public Health Nutrition.
Ann Nutr Metab
72
202-209
2018
Homo sapiens
Enko, D; Meinitzer, A; Brandmayr, W; Halwachs-Baumann, G; Schnedl, WJ; Kriegshäuser, G
Association between increased plasma levels of homocysteine and depression observed in individuals with primary lactose malabsorption.
PLoS One
13
e0202567
2018
Homo sapiens
McClure, SB; Magill, C; Podrug, E; Moore, AMT; Harper, TK; Culleton, BJ; Kennett, DJ; Freeman, KH
Fatty acid specific ?13C values reveal earliest Mediterranean cheese production 7,200 years ago.
PLoS One
13
e0202807
2018
Homo sapiens
Fassio, F; Facioni, MS; Guagnini, F
Lactose Maldigestion, Malabsorption, and Intolerance: A Comprehensive Review with a Focus on Current Management and Future Perspectives.
Nutrients
10
2018
Homo sapiens
Lapides, RA; Savaiano, DA
Gender, Age, Race and Lactose Intolerance: Is There Evidence to Support a Differential Symptom Response? A Scoping Review.
Nutrients
10
2018
Homo sapiens
Fischer, C; Kleinschmidt, T
Effect of glucose depletion during the synthesis of galactooligosaccharides using a trienzymatic system.
Enzyme Microb Technol
121
45-50
2019
Aspergillus oryzae
Indrio, F; Dargenio, VN; Giordano, P; Francavilla, R
Preventing and Treating Colic.
Adv Exp Med Biol
2019
Microbiota
Vadgama, N; Pittman, A; Simpson, M; Nirmalananthan, N; Murray, R; Yoshikawa, T; De Rijk, P; Rees, E; Kirov, G; Hughes, D; Fitzgerald, T; Kristiansen, M; Pearce, K; Cerveira, E; Zhu, Q; Zhang, C; Lee, C; Hardy, J; Nasir, J
De novo single-nucleotide and copy number variation in discordant monozygotic twins reveals disease-related genes.
Eur J Hum Genet
27
1121-1133
2019
Bos taurus
Hodges, JK; Cao, S; Cladis, DP; Weaver, CM
Lactose Intolerance and Bone Health: The Challenge of Ensuring Adequate Calcium Intake.
Nutrients
11
2019
Homo sapiens, animal
Buzás, GM
[Birth-cohort analysis in adult-type hypolactasia].
Orv Hetil
160
549-554
2019
Homo sapiens
Lai, L; Liu, T; Yan, M; Shang, D; Qian, J; Hao, C; Xue, J
Abnormal glucose metabolism and galactose-deficient immunoglobulin A1 (IgA1) synthesis: a possible mechanism of IgA nephropathy.
Discov Med
28
39-45
2019
Homo sapiens, Indicator
Xing, S; Zhang, L; Lin, H; Mao, Z; Bao, K; Hao, P; Pei, Z; Li, J; Hu, Z
Lactose induced redox-dependent senescence and activated Nrf2 pathway.
Int J Clin Exp Pathol
12
2034-2045
2019
Homo sapiens
Grillo, KM; Dunne, J; Marshall, F; Prendergast, ME; Casanova, E; Gidna, AO; Janzen, A; Karega-Munene, ; Keute, J; Mabulla, AZP; Robertshaw, P; Gillard, T; Walton-Doyle, C; Whelton, HL; Ryan, K; Evershed, RP
Molecular and isotopic evidence for milk, meat, and plants in prehistoric eastern African herder food systems.
Proc Natl Acad Sci U S A
117
9793-9799
2020
Bos taurus, Homo sapiens, Capra hircus, Ovis aries, animal, plant
Facioni, MS; Raspini, B; Pivari, F; Dogliotti, E; Cena, H
Nutritional management of lactose intolerance: the importance of diet and food labelling.
J Transl Med
18
260
2020
Homo sapiens
Fedota, O; Babalian, V; Ryndenko, V; Belyaev, S; Beloz?rov, I
LACTOSE TOLERANCE AND RISK OF MULTIFACTORIAL DISEASES ON THE EXAMPLE OF GASTROINTESTINAL TRACT AND BONE TISSUEPATHOLOGIES.
Georgian Med News
109-113
2020
Homo sapiens
Ruiz-Arenas, C; Cáceres, A; López, M; Pelegrí-Sisó, D; González, J; González, JR
Identifying chromosomal subpopulations based on their recombination histories advances the study of the genetic basis of phenotypic traits.
Genome Res
30
1802-1814
2020
Drosophila melanogaster, Homo sapiens
Fischer, C; Kleinschmidt, T
Synthesis of Galactooligosaccharides in Milk and Whey: A Review.
Compr Rev Food Sci Food Saf
17
678-697
2018
Aspergillus oryzae
Bleasdale, M; Richter, KK; Janzen, A; Brown, S; Scott, A; Zech, J; Wilkin, S; Wang, K; Schiffels, S; Desideri, J; Besse, M; Reinold, J; Saad, M; Babiker, H; Power, RC; Ndiema, E; Ogola, C; Manthi, FK; Zahir, M; Petraglia, M; Trachsel, C; Nanni, P; Grossmann, J; Hendy, J; Crowther, A; Roberts, P; Goldstein, ST; Boivin, N
Ancient proteins provide evidence of dairy consumption in eastern Africa.
Nat Commun
12
632
2021
Homo sapiens
Movahedpour, A; Ahmadi, N; Ghalamfarsa, F; Ghesmati, Z; Khalifeh, M; Maleksabet, A; Shabaninejad, Z; Taheri-Anganeh, M; Savardashtaki, A
?-Galactosidase: From its source and applications to its recombinant form.
Biotechnol Appl Biochem
2021
Embryophyta, Metazoa
Kleinbielen, T; Palencia-Madrid, L; Garcia-Ibarbia, C; Ortiz, F; Riancho, JA; M de Pancorbo, M
Association of LCT -13910C>T polymorphism and hip fracture in a cohort of older adult population from Northern Spain.
Gene
783
145560
2021
Homo sapiens
Porzi, M; Burton-Pimentel, KJ; Walther, B; Vergères, G
Development of Personalized Nutrition: Applications in Lactose Intolerance Diagnosis and Management.
Nutrients
13
2021
Microbiota
Dorau, R; Jensen, PR; Solem, C
Purified lactases versus whole-cell lactases-the winner takes it all.
Appl Microbiol Biotechnol
105
4943-4955
2021
plant, Bacteria
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