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Information on EC 3.13.1.3 - 2'-hydroxybiphenyl-2-sulfinate desulfinase and Organism(s) Rhodococcus sp. and UniProt Accession P54997

for references in articles please use BRENDA:EC3.13.1.3
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IUBMB Comments
The enzyme from Rhodococcus sp. strain IGTS8 is encoded by the plasmid-encoded dibenzothiophene-desulfurization (dsz) operon. The enzyme has a narrow substrate specificity with biphenyl-2-sulfinate being the only other substrate known to date .
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This record set is specific for:
Rhodococcus sp.
UNIPROT: P54997
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The taxonomic range for the selected organisms is: Rhodococcus sp.
The enzyme appears in selected viruses and cellular organisms
Synonyms
2'-hydroxybiphenyl-2-sulfinate desulfinase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
2-(2'-hydroxyphenyl)benzene sulfinate hydrolase
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2-(2-hydroxyphenyl)benzenesulfinate:H2O hydrolase
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gene dszB-encoded hydrolase
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hydrolase, 2,(2'-hydroxyphenyl)benzene sulfinate
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
desulfination
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oxidation
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reduction
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PATHWAY SOURCE
PATHWAYS
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SYSTEMATIC NAME
IUBMB Comments
2'-hydroxybiphenyl-2-sulfinate sulfohydrolase
The enzyme from Rhodococcus sp. strain IGTS8 is encoded by the plasmid-encoded dibenzothiophene-desulfurization (dsz) operon. The enzyme has a narrow substrate specificity with biphenyl-2-sulfinate being the only other substrate known to date [2].
CAS REGISTRY NUMBER
COMMENTARY hide
198154-06-2
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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
2-(2-hydroxyphenyl)benzenesulfinate + H2O
2-hydroxybiphenyl + sulfite
show the reaction diagram
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CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
DszB and DszB C27S mutant complexed with biphenyl-2-sulfinic acid are crystallized. The crystals of DszB belong to the orthorhombic P2(1)2(1)2(1) space group, with unit-cell parameters a = 36.7 A, b = 82.6 A, c = 139.6 A, and contain one molecule of DszB in the asymmetric unit. Crystals of DszB C27S complexed with biphenyl-2-sulfinic acid belong to space group C2 with unit-cell parameters a = 153.4 A, b = 45.9 A, c = 112.9 A, beta = 115.93°
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PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Lee, W.C.; Ohshiro, T.; Matsubara, T.; Izumi, Y.; Tanokura, M.
Crystallization and preliminary x-ray analyses of desulfurization enzyme DszB and its C27S mutant complexed with biphenyl-2-sulfinic acid
Acta Crystallogr. Sect. D
D60
1636-1638
2004
Rhodococcus sp., Rhodococcus sp. IGTS8
Manually annotated by BRENDA team