Reference on EC 3.1.8.2 - diisopropyl-fluorophosphatase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Cohen, J.A.; Warringa, M.G.P.J.
Purification and properties of dialkylfluorophosphatase
Biochim. Biophys. Acta
26
29-39
1957
Sus scrofa
Hoskin, F.C.G.; Long, R.J.
Purification of a DFP-hydrolyzing enzyme from squid head ganglion
Arch. Biochem. Biophys.
150
548-555
1972
Aplysia sp., Sepiidae, Doryteuthis pealeii, Octopus sp., Peltodoris nobilis, Spisula solidissima
DeFrank, J.J.; Cheng, T.C.
Purification and properties of an organophosphorus acid anhydrase from a halophilic bacterial isolate
J. Bacteriol.
173
1938-1943
1991
Alteromonas sp.
Cheng, T.C.; Harvey, S.P.; Stroup, A.N.
Purification and properties of a highly active organophosphorus acid anhydrolase from Alteromonas undina
Appl. Environ. Microbiol.
59
3138-3140
1993
Pseudoalteromonas undina
Wang, F.; Xiao, M.; Mu, S.
Purification and properties of a diisopropyl-fluorophosphatase from squid Todarodes pacificus steenstrup
J. Biochem. Toxicol.
8
161-166
1993
Todarodes pacificus
Kopec-Smith, K.; Deschamps, J.R.; Loomis, L.D.; Ward, K.B.
A partial primary structure of squid hepatopancreas organophosphorus acid anhydrolase
Chem. Biol. Interact.
87
49-54
1993
Doryteuthis pealeii
Landis, W.G.; Anderson, R.S.; Chester, N.A.; Durst, H.D.; Haley, M.V.; Johnson, D.W.; Tauber, R.M.
The organophosphate acid anhydrases of the protozoan, Tetrahymena thermophila, and the clam, Rangia cuneata
ASTM Spec. Tech. Publ.
1027
74-81
1989
Rangia cuneata, Sus scrofa, Tetrahymena thermophila
-
Landis, W.G.; Chester, N.A.; Haley, M.V.; Johnson, D.W.; Tauber, R.M.; Durst, H.D.
Alternative substrates and an inhibitor of the organophosphate acid anhydrase activities of the protozoan, Tetrahymena thermophila
Comp. Biochem. Physiol. C
92
211-216
1989
Sus scrofa, Tetrahymena thermophila
-
Landis, W.G.; Haley, M.V.; Johnson, D.W.
Kinetics of the DFPase activity in Tetrahymena thermophila
J. Protozool.
33
216-218
1986
Tetrahymena thermophila
Hoskin, F.C.G.; Prusch, R.D.
Characterization of a DFP-hydrolyzing enzyme in squid posterior salivary gland by use of Soman, DFP and manganous ion
comp. Biochem. Physiol. C
75
17-20
1983
Rattus norvegicus, Loligo sp.
Garden, J.M.; Hause, S.K.; Hoskin, F.C.G.; Roush, A.H.
Comparison of DFP-hydrolyzing enzyme purified from head ganglion and hepatopancreas of squid (Loligo pealei) by means of isoelectric focusing
Comp. Biochem. Physiol. C
52
95-98
1975
Doryteuthis pealeii
Hoskin, F.C.G.
Squid nerve type DFPase. Molecular structures
Jerus. Symp. Quantum Chem. Biochem.
7
209-211
1974
Loligo sp.
-
Koepke, J.; Scharff, E.I.; Lucke, C.; Ruterjans, H.; Fritzsch, G.
Atomic resolution crystal structure of squid ganglion DFPase
Acta Crystallogr. Sect. D
58
1757-1759
2002
Loligo sp.
Scharff, E.I.; Lucke, C.; Fritzsch, G.; Koepke, J.; Hartleib, J.; Dierl, S.; Ruterjans, H.
Crystallization and preliminary X-ray crystallographic analysis of DFPase from Loligo vulgaris
Acta Crystallogr. Sect. D
57
148-149
2001
Loligo vulgaris
Cheng, T.C.; Harvey, S.P.; Chen, G.L.
Cloning and expression of a gene encoding a bacterial enzyme for decontamination of organophosphorus nerve agents and nucleotide sequence of the enzyme
Appl. Environ. Microbiol.
62
1636-1641
1996
Alteromonas sp.
Hill, C.M.; Li, W.S.; Cheng, T.C.; DeFrank, J.J.; Raushel, F.M.
Stereochemical specificity of organophosphorus acid anhydrolase toward p-nitrophenyl analogs of soman and sarin
Bioorg. Chem.
29
27-35
2001
Alteromonas sp.
Hartleib, J.; Ruterjans, H.
High-yield expression, purification, and characterization of the recombinant diisopropylfluorophosphatase from Loligo vulgaris
Protein Expr. Purif.
21
210-219
2001
Loligo vulgaris
Hartleib, J.; Ruterjans, H.
Insights into the reaction mechanism of the diisopropyl fluorophosphatase from Loligo vulgaris by means of kinetic studies, chemical modification and site-directed mutagenesis
Biochim. Biophys. Acta
1546
312-324
2001
Loligo vulgaris
Hill, C.M.; Wu, F.; Cheng, T.C.; DeFrank, J.J.; Raushel, F.M.
Substrate and stereochemical specificity of the organophosphorus acid anhydrolase from Alteromonas sp. JD6.5 toward p-nitrophenyl phosphotriesters
Bioorg. Med. Chem. Lett.
10
1285-1288
2000
Alteromonas sp.
Hoskin, F.C.; Walker, J.E.; Mello, C.M.
Organophosphorus acid anhydrolase in slime mold, duckweed and mung bean: a continuing search for a physiological role and a natural substrate
Chem. Biol. Interact.
119-120
399-404
1999
Dictyostelium discoideum, no activity in Lemna minor, Vigna radiata, Landoltia punctata
Petrikovics, I.; Cheng, T.C.; Papahadjopoulos, D.; Hong, K.; Yin, R.; DeFrank, J.J.; Jaing, J.; Song, Z.H.; McGuinn, W.D.; Sylvester, D.; Pei, L.; Madec, J.; Tamulinas, C.; Jaszberenyi, J.C.; Barcza, T.; Way, J.L.
Long circulating liposomes encapsulating organophosphorus acid anhydrolase in diisopropylfluorophosphate antagonism
Toxicol. Sci.
57
16-21
2000
Alteromonas sp.
Katsemi, V.; Lucke, C.; Koepke, J.; Lohr, F.; Maurer, S.; Fritzsch, G.; Ruterjans, H.
Mutational and structural studies of the diisopropylfluorophosphatase from Loligo vulgaris shed new light on the catalytic mechanism of the enzyme
Biochemistry
44
9022-9033
2005
Loligo vulgaris (Q7SIG4), Loligo vulgaris
Letant, S.E.; Kane, S.R.; Hart, B.R.; Hadi, M.Z.; Cheng, T.C.; Rastogi, V.K.; Reynolds, J.G.
Hydrolysis of acetylcholinesterase inhibitors--organophosphorus acid anhydrolase enzyme immobilization on photoluminescent porous silicon platforms
Chem. Commun. (Camb.)
2005
851-853
2005
Alteromonas sp., Alteromonas sp. JD6.5
Harvey, S.P.; Kolakowski, J.E.; Cheng, T.C.; Rastogi, V.K.; Reiff, L.P.; DeFrank, J.J.; Raushel, F.M.; Hill, C.
Stereospecificity in the enzymatic hydrolysis of cyclosarin (GF)
Enzyme Microb. Technol.
37
547-555
2005
Alteromonas sp., Pseudoalteromonas haloplanktis, Alteromonas sp. JD6.5
-
Kondo, Y.; Ishigami, A.; Kubo, S.; Handa, S.; Gomi, K.; Hirokawa, K.; Kajiyama, N.; Chiba, T.; Shimokado, K.; Maruyama, N.
Senescence marker protein-30 is a unique enzyme that hydrolyzes diisopropyl phosphorofluoridate in the liver
FEBS Lett.
570
57-62
2004
Mus musculus, Rattus norvegicus, Rattus norvegicus (Q03336)
Wang, S.H.; Zhi, Q.W.; Sun, M.J.
Dual activities of human prolidase
Toxicol. In Vitro
20
71-77
2006
Homo sapiens
Blum, M.M.; Koglin, A.; Rueterjans, H.; Schoenborn, B.; Langan, P.; Chen, J.C.
Preliminary time-of-flight neutron diffraction study on diisopropyl fluorophosphatase (DFPase) from Loligo vulgaris
Acta Crystallogr. Sect. F
63
42-45
2007
Loligo vulgaris
Blum, M.M.; Loehr, F.; Richardt, A.; Rueterjans, H.; Chen, J.C.
Binding of a designed substrate analogue to diisopropyl fluorophosphatase: implications for the phosphotriesterase mechanism
J. Am. Chem. Soc.
128
12750-12757
2006
Loligo vulgaris (Q7SIG4)
Gaeb, J.; Melzer, M.; Kehe, K.; Richardt, A.; Blum, M.M.
Quantification of hydrolysis of toxic organophosphates and organophosphonates by diisopropyl fluorophosphatase from Loligo vulgaris by in situ Fourier transform infrared spectroscopy
Anal. Biochem.
385
187-193
2009
Loligo vulgaris
Blum, M.M.; Mustyakimov, M.; Rueterjans, H.; Kehe, K.; Schoenborn, B.P.; Langan, P.; Chen, J.C.
Rapid determination of hydrogen positions and protonation states of diisopropyl fluorophosphatase by joint neutron and X-ray diffraction refinement
Proc. Natl. Acad. Sci. USA
106
713-718
2009
Loligo vulgaris (Q7SIG4)
Blum, M.M.; Tomanicek, S.J.; John, H.; Hanson, B.L.; Rueterjans, H.; Schoenborn, B.P.; Langan, P.; Chen, J.C.
X-ray structure of perdeuterated diisopropyl fluorophosphatase (DFPase): perdeuteration of proteins for neutron diffraction
Acta Crystallogr. Sect. F
66
379-385
2010
Loligo vulgaris (Q7SIG4)
Gaeb, J.; Melzer, M.; Kehe, K.; Wellert, S.; Hellweg, T.; Blum, M.M.
Monitoring the hydrolysis of toxic organophosphonate nerve agents in aqueous buffer and in bicontinuous microemulsions by use of diisopropyl fluorophosphatase (DFPase) with 1H-31P HSQC NMR spectroscopy
Anal. Bioanal. Chem.
396
1213-1221
2010
Loligo vulgaris
Choi, M.S.; Saxena, A.; Chilukuri, N.
A strategy for the production of soluble human senescence marker protein-30 in Escherichia coli
Biochem. Biophys. Res. Commun.
393
509-513
2010
Homo sapiens
Blum, M.M.; Chen, J.C.
Structural characterization of the catalytic calcium-binding site in diisopropyl fluorophosphatase (DFPase)-Comparison with related beta-propeller enzymes
Chem. Biol. Interact.
187
373-379
2010
Loligo vulgaris (Q7SIG4)
Melzer, M.; Chen, J.C.; Heidenreich, A.; Gaeb, J.; Koller, M.; Kehe, K.; Blum, M.M.
Reversed enantioselectivity of diisopropyl fluorophosphatase against organophosphorus nerve agents by rational design
J. Am. Chem. Soc.
131
17226-17232
2009
Loligo vulgaris (Q7SIG4)
Vyas, N.K.; Nickitenko, A.; Rastogi, V.K.; Shah, S.S.; Quiocho, F.A.
Structural insights into the dual activities of the nerve agent degrading organophosphate anhydrolase/prolidase
Biochemistry
49
547-559
2010
Alteromonas sp. (Q44238), Alteromonas sp. JD6.5 (Q44238)
Chen, J.C.; Mustyakimov, M.; Schoenborn, B.P.; Langan, P.; Blum, M.M.
Neutron structure and mechanistic studies of diisopropyl fluorophosphatase (DFPase)
Acta Crystallogr. Sect. D
66
1131-1138
2010
Loligo vulgaris
Theriot, C.M.; Grunden, A.M.
Hydrolysis of organophosphorus compounds by microbial enzymes
Appl. Microbiol. Biotechnol.
89
35-43
2011
Alteromonas sp., Pseudoalteromonas undina, Brevundimonas diminuta, Flavobacterium sp., Pseudoalteromonas haloplanktis, Alteromonas sp. JD6.5
Zhao, L.; Gattas-Asfura, K.M.; Xu, J.; Patel, R.A.; Dadlani, A.; Sillero-Mahinay, M.; Cushmore, M.; Rastogi, V.K.; Shah, S.S.; Leblanc, R.M.
Organophosphorus acid anhydrolase bio-template for the synthesis of CdS quantum dots
Chem. Commun. (Camb. )
47
7242-7244
2011
Pseudomonas aeruginosa
Wellert, S.; Tiersch, B.; Koetz, J.; Richardt, A.; Lapp, A.; Holderer, O.; Gaeb, J.; Blum, M.M.; Schulreich, C.; Stehle, R.; Hellweg, T.
The DFPase from Loligo vulgaris in sugar surfactant-based bicontinuous microemulsions: structure, dynamics, and enzyme activity
Eur. Biophys. J.
40
761-774
2011
Loligo vulgaris
Belinskaya, T.; Pattabiraman, N.; diTargiani, R.; Choi, M.; Saxena, A.
Differences in amino acid residues in the binding pockets dictate substrate specificities of mouse senescence marker protein-30, human paraoxonase1, and squid diisopropylfluorophosphatase
Biochim. Biophys. Acta
1824
701-710
2012
Loligo vulgaris (Q7SIG4)
Wymore, T.; Field, M.J.; Langan, P.; Smith, J.C.; Parks, J.M.
Hydrolysis of DFP and the nerve agent (S)-sarin by DFPase proceeds along two different reaction pathways: Implications for engineering bioscavengers
J. Phys. Chem. B
118
4479-4489
2014
Loligo vulgaris (Q7SIG4)
Latifi, A.M.; Karami, A.; Khodi, S.
Efficient surface display of diisopropylfluorophosphatase (DFPase) in E. coli for biodegradation of toxic organophosphorus compounds (DFP and Cp)
Appl. Biochem. Biotechnol.
177
624-636
2015
Loligo vulgaris (Q7SIG4), Loligo vulgaris
Tripathy, R.K.; Aggarwal, G.; Bajaj, P.; Kathuria, D.; Bharatam, P.V.; Pande, A.H.
Towards understanding the catalytic mechanism of human paraoxonase 1 experimental and in silico mutagenesis studies
Appl. Biochem. Biotechnol.
182
1642-1662
2017
Homo sapiens (P27169)
Goldsmith, M.; Eckstein, S.; Ashani, Y.; Greisen, P.; Leader, H.; Sussman, J.L.; Aggarwal, N.; Ovchinnikov, S.; Tawfik, D.S.; Baker, D.; Thiermann, H.; Worek, F.
Catalytic efficiencies of directly evolved phosphotriesterase variants with structurally different organophosphorus compounds in vitro
Arch. Toxicol.
90
2711-2724
2016
Brevundimonas diminuta (P0A434)
Allahyari, H.; Latifi, A.
Diisopropyl-fluorophosphatase as a catalytic bioscavenger
J. Appl. Biotechnol. Rep.
3
477-482
2016
Loligo vulgaris (Q7SIG4)
-
Zhang, H.; Yang, L.; Ma, Y.Y.; Zhu, C.; Lin, S.; Liao, R.Z.
Theoretical studies on catalysis mechanisms of serum paraoxonase 1 and phosphotriesterase diisopropyl fluorophosphatase suggest the alteration of substrate preference from paraoxonase to DFP
Molecules
23
1660
2018
Loligo vulgaris (Q7SIG4)
Li, D.; Zhang, Y.; Song, H.; Lu, L.; Liu, D.; Yuan, Y.
Aminoalcohol-induced activation of organophosphorus hydrolase (OPH) towards diisopropylfluorophosphate (DFP)
PLoS ONE
12
e0169937
2017
Sphingobium fuliginis (P0A433)
Yun, H.; Yu, J.; Kim, S.; Lee, N.; Lee, J.; Lee, S.; Kim, N.D.; Yu, C.; Rho, J.
Expression and purification of biologically active recombinant human paraoxonase 1 from a Drosophila S2 stable cell line
Protein Expr. Purif.
131
34-41
2017
Homo sapiens (P27169)
Xu, C.; Yang, L.; Yu, J.; Liao, R.
What roles do the residue Asp229 and the coordination variation of calcium play of the reaction mechanism of the diisopropyl-fluorophosphatase? A DFT investigation
Theoret. Chem. Accounts
135
1-11
2016
Loligo vulgaris (Q7SIG4)
-
Xu, C.; Yang, L.; Yu, J.; Liao, R.
What roles do the residue Asp229 and the coordination variation of calcium play of the reaction mechanism of the diisopropyl-fluorophosphatase? A DFT investigation
Theoret. Chem. Accounts
135
138
2016
Loligo vulgaris (Q7SIG4)
-
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