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2-O-alpha-D-galactosaminyl-1-phosphatidyl-D-chiro-inositol + H2O
?
-
-
-
-
?
2-O-alpha-D-glucosaminyl-1-phosphatidyl-D-chiro-inositol + H2O
?
-
-
-
-
?
3-O-alpha-D-galactosaminyl-2-phosphatidyl-L-chiro-inositol + H2O
?
3-O-alpha-D-glycosaminyl-2-phosphatidyl-L-chiro-inositol + H2O
?
-
-
-
-
?
6-O-alpha-D-glucosaminylphosphatidylinositol + H2O
?
-
-
-
-
?
alkaline phosphatase + H2O
?
glycosylphosphatidylinositol-anchor intermediates + H2O
?
-
-
-
-
?
glycosylphosphatidylinositol-anchored placental alkaline phosphatase + H2O
?
-
-
-
-
?
glycosylphosphatidylinositol-anchored protein + H2O
?
glycosylphosphatidylinositol-anchored proteins
phosphatidic acid + variant membrane protein
-
GPI-PLD is highly specific for the GPI anchor
-
-
ir
glycosylphosphatidylinositol-membrane anchor of Cripto-1
soluble Cripto-1 + phosphatidic acid
-
-
-
-
ir
membrane form of variant-surface-glycoprotein + H2O
phosphatidic acid + variant-surface-glycoprotein inositol
membrane-anchored form of urokinase plasminogen activator + H2O
soluble form of urokinase plasminogen activator
-
i.e. uPAR or CD 87
-
?
membrane-bound carcinoembryonic antigen + H2O
?
membrane-bound mucin binding protein + H2O
free mucin binding protein
-
-
-
?
myristate-labelled membrane form of variant surface glycoprotein from Trypanosoma brucei + H2O
?
-
-
-
-
?
phosphatidylinositol + H2O
diacylglycerol + inositol phosphate
-
-
-
-
?
phosphatidylinositol-glycan-anchor of membrane form of acetylcholinesterase + H2O
?
-
-
-
-
?
phosphatidylinositol-glycan-anchored membrane form of acetylcholinesterase + H2O
soluble acetylcholinesterase + phosphatidic acid
-
isolated from bovine erythrocyte membranes
-
?
Zn2+-glycerophosphocholine cholinephosphodiesterase, amphiphilic form + H2O
Zn2+-glycerophosphocholine cholinephosphodiesterase, hydrophilic form
additional information
?
-
3-O-alpha-D-galactosaminyl-2-phosphatidyl-L-chiro-inositol + H2O
?
-
-
-
-
?
3-O-alpha-D-galactosaminyl-2-phosphatidyl-L-chiro-inositol + H2O
?
-
-
-
-
?
5'-nucleotidase + H2O
?
-
isolated from rat liver
-
-
?
5'-nucleotidase + H2O
?
-
isolated from rat liver
-
-
?
alkaline phosphatase + H2O
?
-
isolated from human placenta
-
-
?
alkaline phosphatase + H2O
?
-
isolated from human placenta
-
-
?
glycosylphosphatidylinositol-anchored protein + H2O
?
-
-
-
-
?
glycosylphosphatidylinositol-anchored protein + H2O
?
-
GPI-PDL can influence the steady-state levels of glycosylphosphatidylinositol-anchored proteins by hydrolysing the anchor before and after its attachment to proteins
-
-
?
membrane form of variant-surface-glycoprotein + H2O
phosphatidic acid + variant-surface-glycoprotein inositol
-
-
-
?
membrane form of variant-surface-glycoprotein + H2O
phosphatidic acid + variant-surface-glycoprotein inositol
-
phospholipase D-type hydrolysis
-
?
membrane form of variant-surface-glycoprotein + H2O
phosphatidic acid + variant-surface-glycoprotein inositol
-
-
-
?
membrane form of variant-surface-glycoprotein + H2O
phosphatidic acid + variant-surface-glycoprotein inositol
-
phospholipase D-type hydrolysis
-
?
membrane form of variant-surface-glycoprotein + H2O
phosphatidic acid + variant-surface-glycoprotein inositol
-
-
-
?
membrane form of variant-surface-glycoprotein + H2O
phosphatidic acid + variant-surface-glycoprotein inositol
-
phospholipase D-type hydrolysis
-
?
membrane form of variant-surface-glycoprotein + H2O
phosphatidic acid + variant-surface-glycoprotein inositol
-
-
-
?
membrane form of variant-surface-glycoprotein + H2O
phosphatidic acid + variant-surface-glycoprotein inositol
-
phospholipase D-type hydrolysis
-
?
membrane form of variant-surface-glycoprotein + H2O
phosphatidic acid + variant-surface-glycoprotein inositol
-
-
-
?
membrane form of variant-surface-glycoprotein + H2O
phosphatidic acid + variant-surface-glycoprotein inositol
-
-
-
?
membrane form of variant-surface-glycoprotein + H2O
phosphatidic acid + variant-surface-glycoprotein inositol
-
-
-
-
?
membrane form of variant-surface-glycoprotein + H2O
phosphatidic acid + variant-surface-glycoprotein inositol
-
cleaves phosphodiester linkage to diacylglycerol
-
?
membrane form of variant-surface-glycoprotein + H2O
phosphatidic acid + variant-surface-glycoprotein inositol
-
specific for glycosyl-phosphatidylinositol structure, i.e. the anchoring domain of cell surface proteins
-
?
membrane form of variant-surface-glycoprotein + H2O
phosphatidic acid + variant-surface-glycoprotein inositol
-
phospholipase D-type hydrolysis
-
?
membrane form of variant-surface-glycoprotein + H2O
phosphatidic acid + variant-surface-glycoprotein inositol
-
phospholipase D-type hydrolysis
-
?
membrane form of variant-surface-glycoprotein + H2O
phosphatidic acid + variant-surface-glycoprotein inositol
-
-
-
?
membrane form of variant-surface-glycoprotein + H2O
phosphatidic acid + variant-surface-glycoprotein inositol
-
specific for glycosyl-phosphatidylinositol structure, i.e. the anchoring domain of cell surface proteins
dimyristoylphosphatidic acid
?
membrane form of variant-surface-glycoprotein + H2O
phosphatidic acid + variant-surface-glycoprotein inositol
-
phospholipase D-type hydrolysis
dimyristoylphosphatidic acid
?
membrane form of variant-surface-glycoprotein + H2O
phosphatidic acid + variant-surface-glycoprotein inositol
-
-
-
?
membrane form of variant-surface-glycoprotein + H2O
phosphatidic acid + variant-surface-glycoprotein inositol
-
specific for glycosyl-phosphatidylinositol structure, i.e. the anchoring domain of cell surface proteins
dimyristoylphosphatidic acid
?
membrane form of variant-surface-glycoprotein + H2O
phosphatidic acid + variant-surface-glycoprotein inositol
-
phospholipase D-type hydrolysis
dimyristoylphosphatidic acid
?
membrane-bound carcinoembryonic antigen + H2O
?
-
-
-
-
?
membrane-bound carcinoembryonic antigen + H2O
?
-
cleavage enhances the metastatic potential in colorectal carcinoma cells
-
-
?
Zn2+-glycerophosphocholine cholinephosphodiesterase, amphiphilic form + H2O
Zn2+-glycerophosphocholine cholinephosphodiesterase, hydrophilic form
-
-
-
?
Zn2+-glycerophosphocholine cholinephosphodiesterase, amphiphilic form + H2O
Zn2+-glycerophosphocholine cholinephosphodiesterase, hydrophilic form
-
-
-
?
additional information
?
-
-
no substrate: phosphatidylethanolamine, phosphatidylcholine, phosphatidylinositol derived from HNO2-cleaved mfVSG, overview on substrate specificity
-
-
?
additional information
?
-
-
overexpression of enzyme is lethal to wild-type cells, possibly by catalysing the overproduction of enzyme-derived toxic substances
-
-
?
additional information
?
-
-
the cleavage of chiro-inositol-containing glycerophosphatidylinositols results in both L-chiro- and D-chiro-inositol-containing inositol-phosphoglycans
-
-
?
additional information
?
-
-
cleavage of glycosylphosphatidylinositol-anchor of membrane proteins
-
-
?
additional information
?
-
glycosylphosphatidyl-inositol-anchor cleavage of cell adhesion molecule (csA)
-
-
?
additional information
?
-
-
no substrate: phosphatidylethanolamine, phosphatidylcholine, phosphatidylinositol derived from HNO2-cleaved mfVSG, overview on substrate specificity
-
-
?
additional information
?
-
-
enzyme catalyzed cleavage of glycosylphosphatidylinositol anchor is a potential source of diacylglycerol production to activate protein kinase Calpha
-
-
?
additional information
?
-
-
GPI-PDL activities and their mRNA copies in patients with chronic myeloid leukemia are significantly lower than those in healthy adults. The decreased GPI-PLD expression may reduce the release of GPI-anchored CD55 and CD59 in leukemia cells and finally decrease complement mediated killing of these cells in chronic phase of chronic myeloid leukemia
-
-
?
additional information
?
-
-
GPI-PLD may play a role in islet amyloid formation in type 2 diabetes
-
-
?
additional information
?
-
-
involvement of endogenous GPI-PDI in spontaneous elevated release of carcinoembryonic antigen from human colon cancer cells
-
-
?
additional information
?
-
-
the enzyme plays an active role in lipoprotein metabolism and may contribute to the dyslipidemia of insulin resistant patients
-
-
?
additional information
?
-
-
patients with non-alcoholic fatty liver disease have elevated serum levels and hepatic expression of glycosylphosphatidylinositol-specific phospholipase D. The enzyme may play a role in the pathogenesis of non-alcoholic fatty liver disease and/or its metabolic features
-
-
?
additional information
?
-
-
cleavage of GPI-membrane anchor of carcinoembryonic antigen enhances the metastatic potential in colorectal carcinoma cells
-
-
?
additional information
?
-
cleavage of the glycan-phosphatidylinositol linkage of GPI-anchored proteins
-
-
?
additional information
?
-
-
downregulation of enzyme could play an important role in the control of proinflammatory responses
-
-
?
additional information
?
-
-
glucose and insulin regulate enzyme mRNA levels
-
-
?
additional information
?
-
-
the enzyme is involved in the process of bone formation during mouse embryogenesis
-
-
?
additional information
?
-
-
the enzyme plays role in triglyceride metabolism, affects serum triglyceride levels by altering catabolism of triglyceride-rich lipoproteins. Overexpression of hepatic GPI-PLD induces an increase in fasting and postprandial triglyceride secondary to a decrease in catabolism of triglyceride-rich lipoproteins. GPI-PLD may play a role in the dyslipidemia of the metabolic syndrome
-
-
?
additional information
?
-
-
little or no activity towards phosphatidylinositol or phosphatidylcholine
-
-
?
additional information
?
-
-
little or no activity towards phosphatidylinositol or phosphatidylcholine
-
-
?
additional information
?
-
-
glucose and insulin regulate enzyme mRNA levels
-
-
?
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Adenocarcinoma, Bronchiolo-Alveolar
Down-regulation of glycosylphosphatidylinositol-specific phospholipase D induced by lipopolysaccharide and oxidative stress in the murine monocyte- macrophage cell line RAW 264.7.
Alzheimer Disease
Phosphatidylinositol-glycan-phospholipase D is involved in neurodegeneration in prion disease.
Aneurysm
Discovery of a novel circulating biomarker in patients with abdominal aortic aneurysm: a pilot study using a proteomic approach.
Aneurysm
Plasma glycosylphosphatidylinositol phospholipase D (GPI-PLD) and abdominal aortic aneurysm.
Aortic Aneurysm, Abdominal
Plasma glycosylphosphatidylinositol phospholipase D (GPI-PLD) and abdominal aortic aneurysm.
Atherosclerosis
Glycosylphosphatidylinositol-specific phospholipase D is expressed by macrophages in human atherosclerosis and colocalizes with oxidation epitopes.
Carcinoma
Regulation of carcinoembryonic antigen release from colorectal cancer cells.
Carcinoma, Hepatocellular
Glycosylphosphatidylinositol-specific phospholipase d in nonalcoholic Fatty liver disease: a preliminary study.
Carcinoma, Hepatocellular
Identification of glycoinositol phospholipids in rat liver by reductive radiomethylation of amines but not in H4IIE hepatoma cells or isolated hepatocytes by biosynthetic labeling with glucosamine.
Carcinoma, Hepatocellular
Important roles of glycosylphosphatidylinositol (GPI)-specific phospholipase D and some GPI-anchored proteins in the pathogenesis of hepatocellular carcinoma.
Carcinoma, Hepatocellular
Regulation of glycosylphosphatidylinositol-anchored proteins and GPI-phospholipase D in a c-Myc transgenic mouse model of hepatocellular carcinoma and human HCC.
Carcinoma, Hepatocellular
[Effect of overexpression of glycosylphosphatidylinositol-specific phospholipase D on biological character of hepatocellular carcinoma cell line HepG2.]
Carcinoma, Hepatocellular
[GPI-PLD inhibits the growth of hepatoma cells by down-regulation of PI3K-Akt signaling pathway].
Carcinoma, Squamous Cell
GPI-specific phospholipase D mRNA expression in tumor cells of different malignancy.
Cholestasis
Solubilization of liver alkaline phosphatase isoenzyme during cholestasis in dogs.
Colonic Neoplasms
Evidence for CEA release from human colon cancer cells by an endogenous GPI-PLD enzyme.
Colonic Neoplasms
Regulation of carcinoembryonic antigen release from colorectal cancer cells.
Colorectal Neoplasms
Cleavage of carcinoembryonic antigen induces metastatic potential in colorectal carcinoma.
Creutzfeldt-Jakob Syndrome
Phosphatidylinositol-glycan-phospholipase D is involved in neurodegeneration in prion disease.
Diabetes Mellitus, Type 1
Genetic regulation of mouse glycosylphosphatidylinositol-phospholipase D.
Diabetes Mellitus, Type 1
Increased expression of GPI-specific phospholipase D in mouse models of type 1 diabetes.
Diabetes Mellitus, Type 1
The Clinical Significance of Glycoprotein Phospholipase D Levels in Distinguishing Early Stage Latent Autoimmune Diabetes in Adults and Type 2 Diabetes.
Diabetes Mellitus, Type 2
Glycosylphosphatidylinositol-specific phospholipase D immunoreactivity is present in islet amyloid in type 2 diabetes.
Diabetes Mellitus, Type 2
Impact of glycosylphosphatidylinositol-specific phospholipase D on hepatic diacylglycerol accumulation, steatosis, and insulin resistance in diet-induced obesity.
Diabetes Mellitus, Type 2
MASP1, THBS1, GPLD1 and ApoA-IV are novel biomarkers associated with prediabetes: the KORA F4 study.
Diabetes Mellitus, Type 2
The Clinical Significance of Glycoprotein Phospholipase D Levels in Distinguishing Early Stage Latent Autoimmune Diabetes in Adults and Type 2 Diabetes.
Epilepsy
Genetic Association of Epilepsy and Anti-Epileptic Drugs Treatment in Jordanian Patients.
Epilepsy, Generalized
Genetic Association of Epilepsy and Anti-Epileptic Drugs Treatment in Jordanian Patients.
Fatty Liver
Regulation of glycosylphosphatidylinositol-anchored proteins and GPI-phospholipase D in a c-Myc transgenic mouse model of hepatocellular carcinoma and human HCC.
Glucagonoma
Genetic regulation of mouse glycosylphosphatidylinositol-phospholipase D.
Glucose Intolerance
Impact of glycosylphosphatidylinositol-specific phospholipase D on hepatic diacylglycerol accumulation, steatosis, and insulin resistance in diet-induced obesity.
Hyperglycemia
Increased expression of GPI-specific phospholipase D in mouse models of type 1 diabetes.
Insulin Resistance
Glucose and insulin regulate glycosylphosphatidylinositol-specific phospholipase D expression in islet beta cells.
Insulin Resistance
Glycosylphosphatidylinositol-specific phospholipase D improves glucose tolerance.
Insulin Resistance
Glycosylphosphatidylinositol-specific phospholipase d in nonalcoholic Fatty liver disease: a preliminary study.
Insulin Resistance
Impact of glycosylphosphatidylinositol-specific phospholipase D on hepatic diacylglycerol accumulation, steatosis, and insulin resistance in diet-induced obesity.
Insulin Resistance
Insulin resistance is associated with increased serum levels of glycosylphosphatidylinositol-specific phospholipase D.
Insulin Resistance
Plasma glycosylphosphatidylinositol-specific phospholipase D predicts the change in insulin sensitivity in response to a low-fat but not a low-carbohydrate diet in obese women.
Insulin Resistance
Serum glypican4 and glycosylphosphatidylinositol-specific phospholipase D levels are associated with adipose tissue insulin resistance in obese subjects with different glucose metabolism status.
Insulin Resistance
Upregulated Phospholipase D Activity Towards Glycosylphosphatidylinositol-Anchored Proteins in Micelle-Like Serum Complexes in Diabetic/Obese Rats and Humans.
Insulinoma
Glucose and insulin regulate glycosylphosphatidylinositol-specific phospholipase D expression in islet beta cells.
Insulinoma
Glycosylphosphatidylinositol-specific phospholipase D improves glucose tolerance.
Insulinoma
Regulation of glycosylphosphatidylinositol-specific phospholipase D secretion from beta TC3 cells.
Latent Autoimmune Diabetes in Adults
The Clinical Significance of Glycoprotein Phospholipase D Levels in Distinguishing Early Stage Latent Autoimmune Diabetes in Adults and Type 2 Diabetes.
Leukemia
Effect of glycosylphosphatidylinositol specific phospholipase D gene expression levels on complement mediated killing of leukemic cells in patients with chronic myeloid leukemia.
Leukemia
[Expression and activity of glycosylphosphatidilinoditol-specific phospholipase d mRNA in bone marrow mononuclear cells isolated from patient with acute myeloid leukemia and their significance]
Leukemia
[GPI-PLD gene exon14 polymorphisms of leucocyte in peripheral blood from healthy persons and leukemia patients]
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Effect of glycosylphosphatidylinositol specific phospholipase D gene expression levels on complement mediated killing of leukemic cells in patients with chronic myeloid leukemia.
Leukemia, Myeloid
[Effect of GPI-PLD on adhesion function of bone marrow mononuclear cell from patients with myeloid leukemia and its mechanism]
Leukemia, Myeloid, Acute
[Expression and activity of glycosylphosphatidilinoditol-specific phospholipase d mRNA in bone marrow mononuclear cells isolated from patient with acute myeloid leukemia and their significance]
Leukemia, Myeloid, Acute
[GPI-PLD gene exon14 polymorphisms of leucocyte in peripheral blood from healthy persons and leukemia patients]
Liver Diseases
Glycosylphosphatidylinositol-specific phospholipase d in nonalcoholic Fatty liver disease: a preliminary study.
Liver Diseases
Impact of glycosylphosphatidylinositol-specific phospholipase D on hepatic diacylglycerol accumulation, steatosis, and insulin resistance in diet-induced obesity.
Liver Diseases
Regulation of glycosylphosphatidylinositol-anchored proteins and GPI-phospholipase D in a c-Myc transgenic mouse model of hepatocellular carcinoma and human HCC.
Lymphoma
Saponin-induced release of cell-surface-anchored Thy-1 by serum glycosylphosphatidylinositol-specific phospholipase D.
Metabolic Syndrome
Impact of glycosylphosphatidylinositol-specific phospholipase D on hepatic diacylglycerol accumulation, steatosis, and insulin resistance in diet-induced obesity.
Neoplasm Metastasis
Role of glycosylphosphatidylinositol-specific phospholipase D in the homing of umbilical cord blood, mobilized peripheral blood and bone marrow-derived hematopoietic stem/progenitor cells.
Neoplasms
Activated human neutrophils rapidly release the chemotactically active D2D3 form of the urokinase-type plasminogen activator receptor (uPAR/CD87).
Neoplasms
Biosynthesis of carcinoembryonic antigen (CEA) gene family members expressed in human tumor cell lines: evidence for cleavage of the glycosyl phosphatidyl inositol (GPI) anchor by GPI-PLC and GPI-PLD.
Neoplasms
Cellular glycosylphosphatidylinositol-specific phospholipase D regulates urokinase receptor shedding and cell surface expression.
Neoplasms
Down-regulation of glycosylphosphatidylinositol-specific phospholipase D induced by lipopolysaccharide and oxidative stress in the murine monocyte- macrophage cell line RAW 264.7.
Neoplasms
Glycosylphosphatidylinositol-specific phospholipase D is expressed by macrophages in human atherosclerosis and colocalizes with oxidation epitopes.
Neoplasms
GPI-specific phospholipase D mRNA expression in tumor cells of different malignancy.
Neoplasms
How Glycosylphosphatidylinositol-phospholipase D acts in homing of hematopoietic stem/progenitor cells?
Neoplasms
Inhibition of glycosylphosphatidylinositol (GPI) phospholipase D by suramin-like compounds.
Neoplasms
Regulation of carcinoembryonic antigen release from colorectal cancer cells.
Neoplasms
Role of glycosylphosphatidylinositol-specific phospholipase D in the homing of umbilical cord blood, mobilized peripheral blood and bone marrow-derived hematopoietic stem/progenitor cells.
Neoplasms
[GPI-PLD inhibits the growth of hepatoma cells by down-regulation of PI3K-Akt signaling pathway].
Neuroblastoma
Uptake and intracellular stability of glycosylphosphatidylinositol-specific phospholipase D in neuroblastoma cells.
Neurofibromatoses
Immunolocalization of a glycosylphosphatidylinositol-specific phospholipase D in mast cells found in normal tissue and neurofibromatosis lesions.
Non-alcoholic Fatty Liver Disease
Glycosylphosphatidylinositol-specific phospholipase d in nonalcoholic Fatty liver disease: a preliminary study.
Non-alcoholic Fatty Liver Disease
Impact of glycosylphosphatidylinositol-specific phospholipase D on hepatic diacylglycerol accumulation, steatosis, and insulin resistance in diet-induced obesity.
Obesity
Impact of glycosylphosphatidylinositol-specific phospholipase D on hepatic diacylglycerol accumulation, steatosis, and insulin resistance in diet-induced obesity.
Obesity
Upregulated Phospholipase D Activity Towards Glycosylphosphatidylinositol-Anchored Proteins in Micelle-Like Serum Complexes in Diabetic/Obese Rats and Humans.
Ovarian Neoplasms
GPI-specific phospholipase D mRNA expression in tumor cells of different malignancy.
Pre-Eclampsia
Placental GPI-PLD is of maternal origin and its GPI substrate is absent from placentae of pregnancies associated with pre-eclampsia.
Prediabetic State
MASP1, THBS1, GPLD1 and ApoA-IV are novel biomarkers associated with prediabetes: the KORA F4 study.
Prion Diseases
Phosphatidylinositol-glycan-phospholipase D is involved in neurodegeneration in prion disease.
Sepsis
Glycosylphosphatidylinositol-specific phospholipase D in blood serum: is the liver the only source of the enzyme?
Shock, Septic
Glycosylphosphatidylinositol-specific phospholipase D in blood serum: is the liver the only source of the enzyme?
Stroke
High-Density Lipoprotein Carries Markers that Track with Recovery from Stroke.
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Malik, A.S.; Low, M.G.
Conversion of human placental alkaline phosphatase from a high Mr form to a low Mr form during butanol extraction. An investigation of the role of endogenous phosphoinositide-specific phospholipases
Biochem. J.
240
519-527
1986
Homo sapiens
brenda
Low, M.G.; Prasad, A.R.S.
A phospholipase D specific for the phosphatidylinositol anchor of cell-surface proteins is abundant in plasma
Proc. Natl. Acad. Sci. USA
85
980-984
1988
Bos taurus, Canis lupus familiaris, Gallus gallus, Oryctolagus cuniculus, Equus caballus, Homo sapiens, Rattus norvegicus
brenda
Stieger, S.; Diem, S.; Jakob, A.; Brodbeck, U.
Enzymatic properties of phosphatidylinositol-glycan-specific phospholipase C from rat liver and phosphatidylinositol-glycan-specific phospholipase D from rat serum [published erratum appears in Eur J Biochem 1991 Sep 15;200(3):812]
Eur. J. Biochem.
197
67-73
1991
Rattus norvegicus
brenda
Bowen, R.F.; Raikwar, N.S.; Olson, L.K.; Deeg, M.A.
Glucose and insulin regulate glycosylphosphatidylinositol-specific phospholipase D expression in islet beta cells
Metabolism
50
1489-1492
2001
Mus musculus, Rattus norvegicus
brenda
Deeg, M.A.; Davitz, M.A.
Glycosylphosphatidylinositol-phospholipase D: a tool for glycosylphosphatidylinositol structural analysis
Methods Enzymol.
250
630-640
1995
Bos taurus, Homo sapiens
brenda
Du, X.; Low, M.G.
Down-regulation of glycosylphosphatidylinositol-specific phospholipase D induced by lipopolysaccharide and oxidative stress in the murine monocyte-macrophage cell line RAW 264.7
Infect. Immun.
69
3214-3223
2001
Mus musculus
brenda
Du, X.; Cai, J.; Zhou, J.Z.; Stevens, V.L.; Low, M.G.
Tolerance of glycosylphosphatidylinositol (GPI)-specific phospholipase D overexpression by Chinese hamster ovary cell mutants with aberrant GPI biosynthesis
Biochem. J.
361
113-118
2002
Bos taurus
brenda
Hari, T.; Kunze, H.; Bohn, E.; Brodbeck, U.; Butikofer, P.
Subcellular distribution of glycosylphosphatidylinositol-specific phospholipase D in rat liver
Biochem. J.
320
315-319
1996
Rattus norvegicus
brenda
Hari, T.; Buetikofer, P.; N.Wiesmann, U.; Brodbeck, U.
Uptake and intracellular stability of glycosylphosphatidylinositol-specific phospholipase D in neuroblastoma cells
Biochim. Biophys. Acta
1355
293-302
1997
Bos taurus
brenda
Kueng, M.; Buetikofer, P.; Brodbeck, U.; Stadelmann, B.
Expression of intracellular and GPI-anchored forms of GPI-specific phospholipase D in COS-1 cells
Biochim. Biophys. Acta
1357
329-338
1997
Bos taurus (P80109)
brenda
Lee, J.Y.; Kim, M.R.; Sok, D.E.
Enzymatic release of Zn2+-glycerophosphocholine cholinephosphodiesterase from brain membranes by glycosylphosphatidylinositol-specific phospholipases and its regulation
Neurochem. Res.
23
899-905
1998
Bos taurus
brenda
Lee, J.Y.; Lee, H.J.; Kim, M.R.; Myung, P.K.; Sok, D.E.
Regulation of brain glycosylphosphatidylinositol-specific phospholipase D by natural amphiphiles
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Homo sapiens, Rattus norvegicus
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Homo sapiens, Rattus norvegicus (Q8R2H5)
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Bos taurus (P80109)
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Homo sapiens
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Mus musculus (O70362), Mus musculus
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Homo sapiens
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Bos taurus
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Homo sapiens (P80108)
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Homo sapiens
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Homo sapiens
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Homo sapiens
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Mus musculus, Mus musculus C57BL/6
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Lindqvist, M.; Wallinder, J.; Bergstroem, J.; Henriksson, A.E.
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Homo sapiens
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Masuda, S.; Fujishima, Y.; Maeda, N.; Tsugawa-Shimizu, Y.; Nakamura, Y.; Tanaka, Y.; Obata, Y.; Fukuda, S.; Nagao, H.; Kita, S.; Nishizawa, H.; Shimomura, I.
Impact of glycosylphosphatidylinositol-specific phospholipase D on hepatic diacylglycerol accumulation, steatosis, and insulin resistance in diet-induced obesity
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316
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Homo sapiens (P80108), Homo sapiens, Mus musculus (Q7TNZ4), Rattus norvegicus (Q8R2H5)
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Ritorto, M.S.; Rhode, H.; Vogel, A.; Borlak, J.
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Mus musculus (O70362), Mus musculus, Homo sapiens (P80108), Homo sapiens
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Jin, J.K.; Jang, B.; Jin, H.T.; Choi, E.K.; Jung, C.G.; Akatsu, H.; Kim, J.I.; Carp, R.I.; Kim, Y.S.
Phosphatidylinositol-glycan-phospholipase D is involved in neurodegeneration in prion disease
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Mus musculus (O70362), Homo sapiens (P80108), Homo sapiens
brenda