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Information on EC 3.1.4.44 - glycerophosphoinositol glycerophosphodiesterase and Organism(s) Homo sapiens and UniProt Accession Q9NZC3

for references in articles please use BRENDA:EC3.1.4.44
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This record set is specific for:
Homo sapiens
UNIPROT: Q9NZC3 not found.
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The taxonomic range for the selected organisms is: Homo sapiens
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Synonyms
mir16, glycerophosphodiester phosphodiesterase domain containing 5, gde1/mir16, glycerophosphoinositol phosphodiesterase, gpi-pde, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
GDE1/MIR16
-
glycerophosphoinositol phosphodiesterase
-
membrane interacting protein of regulator of G protein signaling 16
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membrane interacting protein of RGS16
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glycerophosphoinositol glycerophosphohydrolase
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-
-
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phosphodiesterase, glycerophosphoinositol
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-
-
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sn-glycero(3)phosphoinositol glycerophosphohydrolase
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-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
hydrolysis of phosphoric ester
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-
-
-
SYSTEMATIC NAME
IUBMB Comments
1-(sn-glycero-3-phospho)-1D-myo-inositol glycerophosphohydrolase
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CAS REGISTRY NUMBER
COMMENTARY hide
72414-13-2
not distinguished from EC 3.1.4.43
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
glycerophosphoinositol + H2O
glycerol 3-phosphate + inositol
show the reaction diagram
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-
-
?
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
glycerophosphoinositol + H2O
glycerol 3-phosphate + inositol
show the reaction diagram
-
-
-
?
pI VALUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
6.51
calculated from the deduced amino acid sequence
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
SwissProt
Manually annotated by BRENDA team
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
DNA-template obtained from a brain cDNA library
Manually annotated by BRENDA team
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
GDE1_HUMAN
331
1
37718
Swiss-Prot
Secretory Pathway (Reliability: 1)
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
37700
x * 37700, calculated from the deduced amino acid sequence
SUBUNIT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
?
x * 37700, calculated from the deduced amino acid sequence
POSTTRANSLATIONAL MODIFICATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
additional information
several potential phosphorylation sites detected, possible regulation by kinase phosphorylation
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expressed as GST-tag fusion protein in Escherichia coli BL21(DE3) Gold
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Yanaka, N.; Nogusa, Y.; Fujioka, Y.; Yamashita, Y.; Kato, N.
Involvement of membrane protein GDE2 in retinoic acid-induced neurite formation in Neuro2A cells
FEBS Lett.
581
712-718
2007
Homo sapiens (Q9NZC3), Mus musculus
Manually annotated by BRENDA team