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The enzyme appears in viruses and cellular organisms
Synonyms
cyclic hydrolase, inositol 1,2-cyclic phosphate 2-phosphohydrolase, d-myo-inositol 1:2-cyclic phosphate 2-inositolphosphohydrolase, inositol-(1,2)-cyclic-phosphate 2-inositolphosphohydrolase,
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1,2-cyclic-inositol-phosphate phosphodiesterase
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cyclic-inositol 1,2-phosphate 2-phosphohydrolase
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D-inositol 1,2-cyclic phosphate 2-phosphohydrolase
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D-myo-inositol 1:2-cyclic phosphate 2-inositolphosphohydrolase
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D-myo-inositol 1:2-cyclic phosphate 2-phosphohydrolase
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D-myoinositol 1,2-cyclic phosphate 2-phosphohydrolase
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EC 3.1.4.36
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formerly
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inositol 1,2-cyclic phosphate 2-phosphohydrolase
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inositol-(1,2)-cyclic-phosphate 2-inositolphosphohydrolase
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inositol-1:2-cyclic phosphate-2-phosphohydrolase
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phosphodiesterase, glycerophosphoinositol
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1-(sn-glycero-3-phospho)-1D-myo-inositol + H2O = glycerol + 1D-myo-inositol 1-phosphate
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hydrolysis of phosphoric ester
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1-(sn-glycero-3-phospho)-1D-myo-inositol inositolphosphohydrolase
This enzyme also hydrolyses Ins(cyclic1,2)P to Ins-1-P
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72414-13-2
not distinguished from EC 3.1.4.44
9076-91-9
formerly EC 3.1.4.43
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D-myo-inositol 1,2-cyclic phosphate + H2O
1D-myo-inositol 1-phosphate + H+
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sn-glycero-3-phospho-1-inositol
glycerol + inositol cyclic phosphate
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the enzyme can act as a cyclizing phosphotransferase
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sn-glycero-3-phospho-1-inositol + H2O
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catabolism of phosphatidylinositol
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sn-glycero-3-phospho-1-inositol + H2O
glycerol + inositol 1-phosphate
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sn-glycero-3-phospho-1-inositol + H2O
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catabolism of phosphatidylinositol
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Ca2+
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2-3 mM, stimulates
Mn2+
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limited stimulation
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2.2
sn-glycero-3-phospho-1-inositol
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brenda
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outer cortex, brush border of proximal tubules
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GDPD2_HUMAN
539
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61729
Swiss-Prot
Secretory Pathway (Reliability: 4)
GDPD2_MOUSE
539
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61165
Swiss-Prot
Secretory Pathway (Reliability: 4)
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Dawson, R.M.C.; Hemington, N.
A phosphodiesterase in rat kidney cortex that hydrolyses glycerylphosphorylinositol
Biochem. J.
162
241-245
1977
Rattus norvegicus
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