Information on EC 3.1.4.17 - 3',5'-cyclic-nucleotide phosphodiesterase

Word Map on EC 3.1.4.17
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Specify your search results
Select one or more organisms in this record:
Show additional data
Do not include text mining results
Include (text mining) results (more...)
Include results (AMENDA + additional results, but less precise; more...)


The expected taxonomic range for this enzyme is: Bacteria, Eukaryota

EC NUMBER
COMMENTARY hide
3.1.4.17
-
RECOMMENDED NAME
GeneOntology No.
3',5'-cyclic-nucleotide phosphodiesterase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate
show the reaction diagram
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
hydrolysis of phosphoric ester
-
-
-
-
PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
purine metabolism
-
-
Purine metabolism
-
-
SYSTEMATIC NAME
IUBMB Comments
3',5'-cyclic-nucleotide 5'-nucleotidohydrolase
Acts on 3',5'-cyclic AMP, 3',5'-cyclic dAMP, 3',5'-cyclic IMP, 3',5'-cyclic GMP and 3',5'-cyclic CMP.
CAS REGISTRY NUMBER
COMMENTARY hide
9040-59-9
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
1227410 A+, 1265347 A+, 1332923 A+, 1383947 A+, 1395927 A+, 1525949 A+, 1528653 A+, 1528712 A+, 1579910 A+, 1579918 A+, 1579925 A+, 1579929 A+, 1579966 A+, 1579983 A+, 1579993 A+, 1580007 A+, 1580019 A+, 1580038 A+, 1580049 A+, 1580051 A+, 1580056 A+, 2136969 A+, 2145448 A+, 2159596 A+, 2182994 A+, 2188018 A+, 2188229 A+, 2188231 A+, 2188260 A+, 2188300 A+, 2188316 A+, 2188326 A+, 2188469 A+, 2188479 A+, 2198857 A+, 2198861 A+, 2198919 A+, 2198920 A+, 2198950 A+, 2198960 A+, 2198962 A+, 2198963 A+, 2198969 A+, 2198975 A+, 2198976 A+, 2198985 A+, 2199001 A+, 2199003 A+, 2199004 A+, 2199016 A+, 2199020 A+, 2199044 A+, 2199047 A+, 2413056 A+, 2455583 A+, 2497665 A+, 2515819 A+, 2516002 A+, 2516630 A+, 2672413 A+, 2672428 A+, 2672503 A+, 2672531 A+, 2672577 A+, 2672586 A+, 686518 A+, 716280 A+, 765414 A+, 786623 A+, 891585 A+, 891604 A+, 891620 A+, 891666 A+, 891688 A+, 891707 A+, 891782 A+, 891797 A+, 891843 A+, 891888 A+, 891890 A+, 913422 A+, 913783 A+, 913885 A+, 913921 A+, 913932 A+, 913935 A+, 913940 A+, 913944 A+, 913947 A+, 913949 A+, 913957 A+, 913975 A+, 913976 A+, 913988 A+, 913993 A+, 913999 A+, 914002 A+, 914005 A+, 1227209 A++, 1227271 A++, 1579635 A++, 1579643 A++, 1580029 A++, 2187819 A++, 2187831 A++, 2188202 A++, 2188251 A++, 2188315 A++, 2188477 A++, 2198835 A++, 2198846 A++, 2198877 A++, 2198882 A++, 2199019 A++, 2237810 A++, 2672311 A++, 2672496 A++, 668118 A++, 668230 A++, 691887 A++, 713091 A++, 741451 A++, 811010 A++, 811123 A++, 815334 A++, 891168 A++, 891265 A++, 891282 A++, 891317 A++, 891322 A++, 891358 A++, 891410 A++, 891411 A++, 891530 A++, 891535 A++, 891828 A++, 913620 A++, 913781 A++, 913865 A++, 913866 A++, 913896 A++, 1227241 A++, 1227269 A++, 1526001 A++, 1579662 A++, 1579939 A++, 2135496 A++, 2188062 A++, 2188141 A++, 2188189 A++, 2188335 A++, 2188489 A++, 2198737 A++, 2198841 A++, 2198883 A++, 2260079 A++, 2385443 A++, 2545460 A++, 2641263 A++, 2672418 A++, 2672425 A++, 2672427 A++, 2672447 A++, 2672560 A++, 669723 A++, 690367 A++, 816230 A++, 913891 A++, 916317 A++, 913840 A+++, 913874 A+++, 913878 A+++, 913881 A+++, 913952 A+++, 913968 A+++, 891325 A++++, 913452 A++++, 913536 A++++, 913827 A++++, 913872 A++++
-
-
Automatic Mining of ENzyme DAta
product of Rv0805 gene
Uniprot
Manually annotated by BRENDA team
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
1159246 A+, 1227327 A+, 1227468 A+, 1298354 A+, 1341634 A+, 1341637 A+, 135277 A+, 135346 A+, 1381168 A+, 1382258 A+, 1383525 A+, 1384317 A+, 1386934 A+, 1388023 A+, 1388083 A+, 1388392 A+, 1420285 A+, 1462033 A+, 1526517 A+, 1527396 A+, 1527923 A+, 1527987 A+, 1528549 A+, 1533623 A+, 1579593 A+, 1579644 A+, 1579669 A+, 1579696 A+, 1579700 A+, 1579719 A+, 1579747 A+, 1579754 A+, 1579844 A+, 1579879 A+, 1579882 A+, 1579883 A+, 1579890 A+, 1579924 A+, 1579946 A+, 1579967 A+, 1579969 A+, 2105061 A+, 2142875 A+, 2185068 A+, 2187550 A+, 2187668 A+, 2187886 A+, 2187904 A+, 2187927 A+, 2187986 A+, 2188084 A+, 2188159 A+, 2188231 A+, 2188326 A+, 2188387 A+, 2188436 A+, 2188506 A+, 2188540 A+, 2189328 A+, 2198663 A+, 2198685 A+, 2198706 A+, 2198732 A+, 2198748 A+, 2198789 A+, 2198796 A+, 2198808 A+, 2198847 A+, 2198873 A+, 2198907 A+, 2198914 A+, 2198915 A+, 2198919 A+, 2198932 A+, 2198939 A+, 2198942 A+, 2198944 A+, 2198959 A+, 2198960 A+, 2198965 A+, 2198966 A+, 2198979 A+, 2198980 A+, 2198997 A+, 2199003 A+, 2199005 A+, 2199011 A+, 2199013 A+, 2199027 A+, 2199028 A+, 2199033 A+, 2199043 A+, 2210156 A+, 2288478 A+, 2321666 A+, 2346010 A+, 2391655 A+, 2415189 A+, 2424117 A+, 2440042 A+, 2491073 A+, 2511261 A+, 2511793 A+, 2512436 A+, 2513130 A+, 2517467 A+, 2607125 A+, 2612068 A+, 2641784 A+, 2642920 A+, 2661403 A+, 2672286 A+, 2672288 A+, 2672347 A+, 2672359 A+, 2672367 A+, 2672378 A+, 2672395 A+, 2672469 A+, 679763 A+, 681548 A+, 693825 A+, 694373 A+, 715152 A+, 729558 A+, 811928 A+, 812237 A+, 813173 A+, 887406 A+, 890087 A+, 890140 A+, 890178 A+, 890295 A+, 890303 A+, 890387 A+, 890468 A+, 890536 A+, 890751 A+, 891344 A+, 891365 A+, 891366 A+, 891463 A+, 891511 A+, 891560 A+, 891693 A+, 891756 A+, 891757 A+, 891758 A+, 891762 A+, 891792 A+, 891823 A+, 891843 A+, 913353 A+, 913356 A+, 913357 A+, 913367 A+, 913386 A+, 913388 A+, 913396 A+, 913421 A+, 913438 A+, 913439 A+, 913451 A+, 913454 A+, 913469 A+, 913516 A+, 913529 A+, 913549 A+, 913553 A+, 913554 A+, 913557 A+, 913558 A+, 913562 A+, 913564 A+, 913565 A+, 913567 A+, 913571 A+, 913575 A+, 913576 A+, 913583 A+, 913584 A+, 913604 A+, 913629 A+, 913675 A+, 913723 A+, 913777 A+, 913783 A+, 913807 A+, 913836 A+, 913841 A+, 913846 A+, 913849 A+, 913905 A+, 913913 A+, 913916 A+, 913918 A+, 913922 A+, 913924 A+, 913925 A+, 913931 A+, 913936 A+, 913941 A+, 913959 A+, 913960 A+, 913963 A+, 913965 A+, 913966 A+, 913980 A+, 913984 A+, 914003 A+, 916316 A+, 940430 A+, 1028499 A++, 1141171 A++, 1163216 A++, 1220942 A++, 1221722 A++, 1227244 A++, 1227283 A++, 1227312 A++, 1227335 A++, 1227353 A++, 1227354 A++, 1328263 A++, 1339391 A++, 135236 A++, 135268 A++, 1380487 A++, 1380515 A++, 1380729 A++, 1380771 A++, 1380799 A++, 1381940 A++, 1382271 A++, 1382601 A++, 1383568 A++, 1383714 A++, 1383718 A++, 1384401 A++, 1387462 A++, 1525978 A++, 1526025 A++, 1526324 A++, 1526450 A++, 1526686 A++, 1526905 A++, 1526921 A++, 1526950 A++, 1527264 A++, 1527333 A++, 1527366 A++, 1527428 A++, 1528069 A++, 1528161 A++, 1528780 A++, 1579601 A++, 1579681 A++, 1579687 A++, 1579692 A++, 1579695 A++, 1579715 A++, 1579758 A++, 1579774 A++, 1579804 A++, 1579807 A++, 1579811 A++, 1579832 A++, 1579834 A++, 1579839 A++, 1579855 A++, 1579869 A++, 1579895 A++, 1579919 A++, 2135496 A++, 2142741 A++, 2143087 A++, 2143629 A++, 2143639 A++, 2163567 A++, 2176822 A++, 2182547 A++, 2182800 A++, 2187539 A++, 2187579 A++, 2187597 A++, 2187741 A++, 2187750 A++, 2187798 A++, 2187802 A++, 2187808 A++, 2187973 A++, 2187975 A++, 2188126 A++, 2188168 A++, 2188253 A++, 2188295 A++, 2188428 A++, 2188430 A++, 2198669 A++, 2198672 A++, 2198689 A++, 2198698 A++, 2198707 A++, 2198709 A++, 2198712 A++, 2198717 A++, 2198728 A++, 2198744 A++, 2198747 A++, 2198754 A++, 2198757 A++, 2198762 A++, 2198763 A++, 2198773 A++, 2198776 A++, 2198783 A++, 2198791 A++, 2198803 A++, 2198811 A++, 2198812 A++, 2198818 A++, 2198826 A++, 2198827 A++, 2198830 A++, 2198844 A++, 2198853 A++, 2198854 A++, 2198871 A++, 2198905 A++, 2325583 A++, 2360506 A++, 2385443 A++, 2385950 A++, 2391524 A++, 2391701 A++, 2474501 A++, 2512406 A++, 2512996 A++, 2514924 A++, 2516863 A++, 2557531 A++, 2612081 A++, 2640732 A++, 2640738 A++, 2641005 A++, 2641185 A++, 2641258 A++, 2641396 A++, 2641402 A++, 2642055 A++, 2642212 A++, 2642348 A++, 2642685 A++, 2672263 A++, 2672269 A++, 2672274 A++, 2672313 A++, 2672317 A++, 2672322 A++, 2672337 A++, 2672346 A++, 2672369 A++, 2672379 A++, 2672464 A++, 2672479 A++, 2672481 A++, 2672484 A++, 640738 A++, 648771 A++, 667366 A++, 668118 A++, 681045 A++, 689068 A++, 691716 A++, 811082 A++, 812551 A++, 812552 A++, 814712 A++, 816054 A++, 816230 A++, 889859 A++, 889887 A++, 889922 A++, 889926 A++, 890036 A++, 890082 A++, 890171 A++, 890180 A++, 890330 A++, 890359 A++, 890697 A++, 890702 A++, 890848 A++, 890849 A++, 890882 A++, 890950 A++, 890986 A++, 890988 A++, 891019 A++, 891065 A++, 891137 A++, 891210 A++, 891253 A++, 891305 A++, 892645 A++, 905821 A++, 913370 A++, 913735 A++, 913744 A++, 913758 A++, 913835 A++, 913986 A++, 916200 A++, 1227239 A++, 1227240 A++, 1227245 A++, 1227272 A++, 1341565 A++, 135233 A++, 135265 A++, 135270 A++, 135273 A++, 135413 A++, 1380563 A++, 1382715 A++, 1387692 A++, 1388993 A++, 1525866 A++, 1525910 A++, 1527265 A++, 1527482 A++, 1528710 A++, 1528743 A++, 1531827 A++, 1579603 A++, 1579642 A++, 1579653 A++, 1579659 A++, 1579667 A++, 1579672 A++, 1579761 A++, 1579780 A++, 1579789 A++, 1579790 A++, 1579806 A++, 1579823 A++, 1579830 A++, 2142771 A++, 2143584 A++, 2169850 A++, 2175648 A++, 2187537 A++, 2187544 A++, 2187552 A++, 2187556 A++, 2187572 A++, 2187584 A++, 2187598 A++, 2187638 A++, 2187704 A++, 2187745 A++, 2187751 A++, 2187816 A++, 2187836 A++, 2187844 A++, 2187912 A++, 2187995 A++, 2188030 A++, 2188121 A++, 2188124 A++, 2188136 A++, 2188176 A++, 2188254 A++, 2188292 A++, 2188315 A++, 2188489 A++, 2198667 A++, 2198675 A++, 2198680 A++, 2198682 A++, 2198708 A++, 2198711 A++, 2198715 A++, 2198721 A++, 2198723 A++, 2198736 A++, 2198743 A++, 2198745 A++, 2198779 A++, 2198800 A++, 2198806 A++, 2198820 A++, 2198848 A++, 2198874 A++, 2198883 A++, 2198927 A++, 2199811 A++, 2210135 A++, 2324082 A++, 2391533 A++, 2391534 A++, 2391547 A++, 2513163 A++, 2640716 A++, 2640791 A++, 2642709 A++, 2644374 A++, 2672342 A++, 2672360 A++, 2672361 A++, 2672372 A++, 2672373 A++, 2672385 A++, 2672393 A++, 2672456 A++, 2672544 A++, 652975 A++, 668230 A++, 678559 A++, 742921 A++, 811022 A++, 811060 A++, 811183 A++, 812118 A++, 813370 A++, 816521 A++, 834585 A++, 880544 A++, 889836 A++, 889839 A++, 889856 A++, 889872 A++, 889908 A++, 889912 A++, 889940 A++, 889951 A++, 890038 A++, 890048 A++, 890049 A++, 890248 A++, 890274 A++, 890294 A++, 890301 A++, 890306 A++, 890320 A++, 890325 A++, 890331 A++, 890372 A++, 890592 A++, 890607 A++, 890629 A++, 890650 A++, 890700 A++, 890709 A++, 890734 A++, 890781 A++, 890884 A++, 891121 A++, 891134 A++, 891266 A++, 891294 A++, 891307 A++, 891364 A++, 891486 A++, 891544 A++, 891830 A++, 893225 A++, 913354 A++, 913368 A++, 913369 A++, 913371 A++, 913385 A++, 913397 A++, 913404 A++, 913405 A++, 913406 A++, 913409 A++, 913420 A++, 913426 A++, 913431 A++, 913432 A++, 913445 A++, 913446 A++, 913456 A++, 913459 A++, 913488 A++, 913490 A++, 913514 A++, 913521 A++, 913527 A++, 913538 A++, 913548 A++, 913591 A++, 913595 A++, 913608 A++, 913619 A++, 913623 A++, 913631 A++, 913636 A++, 913637 A++, 913641 A++, 913643 A++, 913646 A++, 913656 A++, 913662 A++, 913663 A++, 913668 A++, 913669 A++, 913674 A++, 913676 A++, 913692 A++, 913697 A++, 913702 A++, 913716 A++, 913717 A++, 913719 A++, 913732 A++, 913742 A++, 913753 A++, 913767 A++, 913768 A++, 913773 A++, 913784 A++, 913785 A++, 913794 A++, 913802 A++, 913805 A++, 913839 A++, 913842 A++, 913866 A++, 913897 A++, 916173 A++, 916291 A++, 940432 A++, 135279 A+++, 651105 A+++, 690858 A+++, 715153 A+++, 723027 A+++, 890112 A+++, 890584 A+++, 913473 A+++, 913479 A+++, 913505 A+++, 913552 A+++, 913592 A+++, 913606 A+++, 913632 A+++, 913635 A+++, 913677 A+++, 913694 A+++, 913718 A+++, 913743 A+++, 913788 A+++, 913819 A+++, 913860 A+++, 913867 A+++, 913879 A+++, 913882 A+++, 913915 A+++, 913934 A+++, 913937 A+++, 913950 A+++, 913956 A+++, 913996 A+++, 135276 A++++, 649518 A++++, 649519 A++++, 890951 A++++, 891120 A++++, 913372 A++++, 913394 A++++, 913435 A++++, 913450 A++++, 913464 A++++, 913466 A++++, 913471 A++++, 913472 A++++, 913475 A++++, 913487 A++++, 913489 A++++, 913492 A++++, 913494 A++++, 913506 A++++, 913509 A++++, 913511 A++++, 913523 A++++, 913614 A++++, 913622 A++++, 913645 A++++, 913654 A++++, 913657 A++++, 913658 A++++, 913659 A++++, 913666 A++++, 913667 A++++, 913679 A++++, 913690 A++++, 913703 A++++, 913707 A++++, 913709 A++++, 913711 A++++, 913715 A++++, 913724 A++++, 913725 A++++, 913746 A++++, 913748 A++++, 913752 A++++, 913761 A++++, 913779 A++++, 913791 A++++, 913798 A++++, 913806 A++++, 913809 A++++, 913817 A++++, 913821 A++++, 913826 A++++, 913833 A++++, 913858 A++++, 913895 A++++
-
-
Automatic Mining of ENzyme DAta
Rattus norvegicus Sprague-Dawley
-
-
-
Manually annotated by BRENDA team
salmon
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
MAR-1
-
-
Manually annotated by BRENDA team
squirrel
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
-
-
-
Automatic Mining of ENzyme DAta
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
malfunction
metabolism
-
in adipocytes, insulin induces formation of macromolecular complexes containing signaling molecules such as IRS-1, PI3K and PKB, proteins involved in PDE3B activation/phosphorylation
physiological function
additional information
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
2',3'-cAMP + H2O
3'-AMP
show the reaction diagram
-
in PdeB the phosphodiesterase activity for 2',3'-cAMP is about 1.7fold higher than that for 3',5'-cAMP
-
-
?
2',3'-cAMP + H2O
5'-AMP
show the reaction diagram
3',5'-cAMP + H2O
5'-AMP
show the reaction diagram
3',5'-cAMP + H2O
adenosine 5'-phosphate
show the reaction diagram
3',5'-cCMP + H2O
5'-CMP
show the reaction diagram
3',5'-cdAMP + H2O
5'-dAMP
show the reaction diagram
-
-
-
-
?
3',5'-cGMP + H2O
5'-AMP
show the reaction diagram
3',5'-cGMP + H2O
5'-GMP
show the reaction diagram
3',5'-cGMP + H2O
guanosine 5'-phosphate
show the reaction diagram
3'-AMP + H2O
?
show the reaction diagram
-
high activity
-
-
?
3'-GMP + H2O
?
show the reaction diagram
-
high activity
-
-
?
5'-ATP + H2O
?
show the reaction diagram
-
-
-
-
?
5'-dAMP + H2O
?
show the reaction diagram
-
low activity
-
-
?
5'-UMP + H2O
?
show the reaction diagram
-
high activity
-
-
?
adenosine 3',5'-cyclic phosphate + H2O
adenosine 5'-phosphate
show the reaction diagram
cAMP + H2O
5'-AMP
show the reaction diagram
-
degradation of extracellular cAMP by isoforms PDE1, PDE7. Degradation of intracellular cAMP by isoform PDE2
-
-
?
cAMP + H2O
AMP
show the reaction diagram
cGMP + H2O
5'-GMP
show the reaction diagram
-
degradation of intracellular cGMP by isoform PDE3
-
-
?
cGMP + H2O
GMP
show the reaction diagram
guanosine 3',5'-cyclic phosphate + H2O
guanosine 5'-phosphate
show the reaction diagram
nucleoside 3',5'-cyclic phosphate + H2O
nucleoside 5'-phosphate
show the reaction diagram
UDP-D-glucose + H2O
?
show the reaction diagram
-
UDP-D-glucose is hydrolyzed by PdeB, but not by PdeA
-
-
?
additional information
?
-