Information on EC 3.1.4.13 - serine-ethanolaminephosphate phosphodiesterase

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The expected taxonomic range for this enzyme is: Gallus gallus

EC NUMBER
COMMENTARY
3.1.4.13
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RECOMMENDED NAME
GeneOntology No.
serine-ethanolaminephosphate phosphodiesterase
REACTION
REACTION DIAGRAM
COMMENTARY
ORGANISM
UNIPROT ACCESSION NO.
LITERATURE
serine phosphoethanolamine + H2O = serine + ethanolamine phosphate
show the reaction diagram
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REACTION TYPE
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
hydrolysis of phosphoric ester
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-
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PATHWAY
KEGG Link
MetaCyc Link
Glycerophospholipid metabolism
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SYSTEMATIC NAME
IUBMB Comments
serine-phosphoethanolamine ethanolaminephosphohydrolase
Acts only on those phosphodiesters that have ethanolamine as a component part of the molecule.
SYNONYMS
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
phosphodiesterase, serine-ethanolamine phosphate
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-
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SEP diesterase
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serine ethanolamine phosphodiester phosphodiesterase
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serine-ethanolamine phosphate phosphodiesterase
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CAS REGISTRY NUMBER
COMMENTARY
37288-20-3
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ORGANISM
COMMENTARY
LITERATURE
SEQUENCE CODE
SEQUENCE DB
SOURCE
SUBSTRATE
PRODUCT                      
REACTION DIAGRAM
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
(Substrate)
LITERATURE
(Substrate)
COMMENTARY
(Product)
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
bis L-serine phosphate + H2O
?
show the reaction diagram
-
4% relative activity to L-serine-phosphoethanolamine
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-
?
bis-(4-nitrophenyl) phoshate + H2O
?
show the reaction diagram
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8% relative activity to L-serine-phosphoethanolamine
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-
?
bis-ethanolamine phosphate + H2O
?
show the reaction diagram
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37% relative activity to L-serine-phosphoethanolamine
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-
?
D-lombricine + H2O
?
show the reaction diagram
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37% relative activity to L-serine-phosphoethanolamine
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-
?
D-serine-phosphoethanolamine + H2O
D-serine + ethanolamine phosphate
show the reaction diagram
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131% relative activity to L-serine-phosphoethanolamine
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?
L-lombricine + H2O
?
show the reaction diagram
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58% relative activity to L-serine-phosphoethanolamine
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-
?
L-serine-phosphoethanolamine + H2O
L-serine + ethanolamine phosphate
show the reaction diagram
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-
-
?
L-serine-phosphoethanolamine + H2O
L-serine + ethanolamine phosphate
show the reaction diagram
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-
-
?
L-serine-phosphoethanolamine + H2O
?
show the reaction diagram
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-
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L-threonine-phosphoethanolamine + H2O
L-threonine + ethanolamine phosphate
show the reaction diagram
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70% relative activity to L-serine-phosphoethanolamine
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?
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
(Substrate)
LITERATURE
(Substrate)
COMMENTARY
(Product)
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
L-serine-phosphoethanolamine + H2O
?
show the reaction diagram
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-
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METALS and IONS
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
additional information
-
no requirement for Ca2+ or Mg2+
KM VALUE [mM]
KM VALUE [mM] Maximum
SUBSTRATE
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
IMAGE
2.2
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D-serine ethanolamine phosphate
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3.6
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L-serine ethanolamine phosphate
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8.8
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L-Threonine ethanolamine phosphate
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SPECIFIC ACTIVITY [µmol/min/mg]
SPECIFIC ACTIVITY MAXIMUM
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
3.83
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pH OPTIMUM
pH MAXIMUM
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
9.5
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pH RANGE
pH RANGE MAXIMUM
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
6.5
11.5
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SOURCE TISSUE
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
SOURCE
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trace amounts
Manually annotated by BRENDA team
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trace amounts
Manually annotated by BRENDA team
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trace amounts
Manually annotated by BRENDA team
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trace amounts
Manually annotated by BRENDA team
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trace amounts in breast muscle
Manually annotated by BRENDA team
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trace amounts
Manually annotated by BRENDA team
LOCALIZATION
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
GeneOntology No.
LITERATURE
SOURCE
STORAGE STABILITY
ORGANISM
UNIPROT ACCESSION NO.
LITERATURE
-20°C, at any stage of fractionation, without loss of activity, up to 9 months
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Purification/COMMENTARY
ORGANISM
UNIPROT ACCESSION NO.
LITERATURE