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Information on EC 3.1.27.B1 - pre-mRNA splicing endonuclease EndA and Organism(s) Sulfurisphaera tokodaii and UniProt Accession Q975R3

for references in articles please use BRENDA:EC3.1.27.B1
preliminary BRENDA-supplied EC number
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Sulfurisphaera tokodaii
UNIPROT: Q975R3
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The taxonomic range for the selected organisms is: Sulfurisphaera tokodaii
The expected taxonomic range for this enzyme is: Sulfurisphaera tokodaii
Reaction Schemes
cleaves at the exon-intron boundaries of cbf5 pre-mRNA
Synonyms
splicing endonuclease EndA, ST0358, STK_03225, STK_03580, STS047, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
splicing endonuclease EndA
Q975R3; F9VMU0
-
ST0358
Q975R3; F9VMU0
subunit
STK_03225
Q975R3; F9VMU0
locus name, subunit
STK_03580
Q975R3; F9VMU0
locus name, subunit
STS047
Q975R3; F9VMU0
subunit
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
cbf5 pre-mRNA fragment + H2O
?
show the reaction diagram
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
cbf5 pre-mRNA fragment + H2O
?
show the reaction diagram
Q975R3; F9VMU0
the enzyme cleaves at the exon-intron boundaries of cbf5 pre-mRNA fragments. The enzyme catalyzes pre-mRNA splicing which is necessary to produce full-length and functional Cbf5 proteins
-
-
?
SUBUNIT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
heterooligomer
Q975R3; F9VMU0
-
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
for the reconstitution of the splicing endonuclease, STS047 with N-terminal S-tag and ST0358 with N-terminal His-tag are independently expressed in Escherichia coli
Q975R3; F9VMU0
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Yoshinari, S.; Itoh, T.; Hallam, S.J.; DeLong, E.F.; Yokobori, S.; Yamagishi, A.; Oshima, T.; Kita, K.; Watanabe, Y.
Archaeal pre-mRNA splicing: a connection to hetero-oligomeric splicing endonuclease
Biochem. Biophys. Res. Commun.
346
1024-1032
2006
Sulfurisphaera tokodaii (Q975R3 and F9VMU0), Sulfurisphaera tokodaii 7 (Q975R3 and F9VMU0)
Manually annotated by BRENDA team