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Information on EC 3.1.26.3 - ribonuclease III and Organism(s) Streptomyces coelicolor and UniProt Accession Q9ZBQ7

for references in articles please use BRENDA:EC3.1.26.3
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EC Tree
     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.26 Endoribonucleases producing 5'-phosphomonoesters
                3.1.26.3 ribonuclease III
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This record set is specific for:
Streptomyces coelicolor
UNIPROT: Q9ZBQ7 not found.
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Word Map
The taxonomic range for the selected organisms is: Streptomyces coelicolor
The enzyme appears in selected viruses and cellular organisms
Synonyms
dicer, dicer1, drosha, dicer-2, rnt1p, ribonuclease iii, dicer-1, rnase d, dcr-1, rnase3, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
double strand-specific endoRNase
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HCS protein
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nuclease, ribo-, D
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-
-
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p241
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ribonuclease D
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-
-
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RNase D
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-
-
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RNase O
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-
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
hydrolysis of phosphoric ester
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-
-
-
CAS REGISTRY NUMBER
COMMENTARY hide
78413-14-6
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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
dsRNA + H2O
mature RNA
show the reaction diagram
members of tRNase III family, which have been implicated in the processing of pre-rRNA, rRNA, polycistronic mRNAs, and small regulatory RNAs, normally cleave duplex segments of RNAs configured as stem-loop structures and are ubiquitous among prokaryotes, eukaryotes, and archaea
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-
?
additional information
?
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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
additional information
?
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
additional information
wild-type and JSE1880 rnc-mutant strains are cultivated on solid R2YE medium
Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
additional information
necessity of involvement of other transcripts for the binding of the double-strand-specific enzyme to the mRNAs is still unknown in the case of Streptomyces
PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
D70A
constructed point mutation, abolishes the catalytic activity of the protein but not its ability to bind to RNA substrates
additional information
PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expressed in Escherichia coli
expressed in Escherichia coli strain BL21
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Sello, J.K.; Buttner, M.J.
The gene encoding RNase III in Streptomyces coelicolor is transcribed during exponential phase and is required for antibiotic production and for proper sporulation
J. Bacteriol.
190
4079-4083
2008
Streptomyces coelicolor
Manually annotated by BRENDA team
Xu, W.; Huang, J.; Cohen, S.N.
Autoregulation of AbsB (RNase III) expression in Streptomyces coelicolor by endoribonucleolytic cleavage of absB operon transcripts
J. Bacteriol.
190
5526-5530
2008
Streptomyces coelicolor (Q9ZBQ7)
Manually annotated by BRENDA team
Gravenbeek, M.L.; Jones, G.H.
The endonuclease activity of RNase III is required for the regulation of antibiotic production by Streptomyces coelicolor
Microbiology
154
3547-3555
2008
Streptomyces coelicolor (Q9ZBQ7), Streptomyces coelicolor, Streptomyces coelicolor M145 (Q9ZBQ7)
Manually annotated by BRENDA team
Setinova, D.; Smidova, K.; Pohl, P.; Music, I.; Bobek, J.
RNase III-binding-mRNAs revealed novel complementary transcripts in Streptomyces
Front. Microbiol.
8
2693
2017
Streptomyces coelicolor (Q9ZBQ7), Streptomyces coelicolor A3(2) (Q9ZBQ7), Streptomyces coelicolor ATCC BAA-471 (Q9ZBQ7), Streptomyces coelicolor M145 (Q9ZBQ7)
Manually annotated by BRENDA team