Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

Disease on EC 3.1.25.1 - deoxyribonuclease (pyrimidine dimer)

Please use the Disease Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Acute Lung Injury
Ribosomal Protein S3 Gene Silencing Protects Against Cigarette Smoke-Induced Acute Lung Injury.
Adenocarcinoma
Differential gene expression in human lung adenocarcinomas and squamous cell carcinomas.
Asthma
Ribosomal protein S3 gene silencing protects against experimental allergic asthma.
Atypical Squamous Cells of the Cervix
MoSnt2-dependent deacetylation of histone H3 mediates MoTor-dependent autophagy and plant infection by the rice blast fungus Magnaporthe oryzae.
Bacterial Infections
Ribosomal protein s3: a multifunctional target of attaching/effacing bacterial pathogens.
SseL Deubiquitinates RPS3 to Inhibit Its Nuclear Translocation.
Breast Neoplasms
Evaluation of the association of heterozygous germline variants in NTHL1 with breast cancer predisposition: an international multi-center study of 47,180 subjects.
Ribosomal protein S3 regulates XIAP expression independently of the NF-?B pathway in breast cancer cells.
Carcinogenesis
Formation of trans-4-hydroxy-2-nonenal- and other enal-derived cyclic DNA adducts from omega-3 and omega-6 polyunsaturated fatty acids and their roles in DNA repair and human p53 gene mutation.
Carcinoma
Chemoprevention of nonmelanoma skin cancer.
Differential gene expression in human lung adenocarcinomas and squamous cell carcinomas.
Measurement of oxidative DNA damage induced by mainstream cigarette smoke in cultured NCI-H292 human pulmonary carcinoma cells.
T4 endonuclease V: review and application to dermatology.
Carcinoma, Basal Cell
Chemoprevention of nonmelanoma skin cancer.
T4 endonuclease V: review and application to dermatology.
Carcinoma, Non-Small-Cell Lung
Phosphorylation of ribosomal protein S3 and antiapoptotic TRAF2 protein mediates radioresistance in non-small cell lung cancer cells.
Carcinoma, Squamous Cell
Differential gene expression in human lung adenocarcinomas and squamous cell carcinomas.
Cockayne Syndrome
Cyclobutane pyrimidine dimers do not fully explain the mutagenicity induced by UVA in Chinese hamster cells.
Defective repair of 5-hydroxy-2'-deoxycytidine in Cockayne syndrome cells and its complementation by Escherichia coli formamidopyrimidine DNA glycosylase and endonuclease III.
Oxidatively damaged DNA repair defect in cockayne syndrome and its complementation by heterologous repair proteins.
The basal levels of 8-oxoG and other oxidative modifications in intact mitochondrial DNA are low even in repair-deficient (Ogg1(-/-)/Csb(-/-)) mice.
Colonic Neoplasms
Ribosomal protein S3 selectively affects colon cancer growth by modulating the levels of p53 and lactate dehydrogenase.
deoxyribonuclease (pyrimidine dimer) deficiency
Pathogen DNA as target for host-generated oxidative stress: role for repair of bacterial DNA damage in Helicobacter pylori colonization.
Dermatitis, Contact
Pyrimidine dimers in DNA initiate systemic immunosuppression in UV-irradiated mice.
Erythema
Topical treatment with liposomes containing T4 endonuclease V protects human skin in vivo from ultraviolet-induced upregulation of interleukin-10 and tumor necrosis factor-alpha.
Fanconi Anemia
Chromosomal instability of fanconi anemia cells is not the consequence of a defective repair activity of the ribosomal protein S3.
Fibrosarcoma
Reduction of invasion in human fibrosarcoma cells by ribosomal protein S3 in conjunction with Nm23-H1 and ERK.
Heart Failure
A novel mtDNA repair fusion protein attenuates maladaptive remodeling and preserves cardiac function in heart failure.
Hepatitis
Evidence of alterations in base excision repair of oxidative DNA damage during spontaneous hepatocarcinogenesis in Long Evans Cinnamon rats.
Ichthyosis
Effect of topically applied T4 endonuclease V in liposomes on skin cancer in xeroderma pigmentosum: a randomised study. Xeroderma Pigmentosum Study Group.
Infections
Pathogen DNA as target for host-generated oxidative stress: role for repair of bacterial DNA damage in Helicobacter pylori colonization.
Removal of T4 endonuclease V-sensitive sites from SV40 DNA after exposure to ultraviolet light.
Keratosis, Actinic
Chemoprevention of nonmelanoma skin cancer.
DNA repair, immunosuppression, and skin cancer.
T4 endonuclease V: review and application to dermatology.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Puncta intended: connecting the dots between autophagy and cell stress networks.
Lung Injury
Mitochondrial Targeted Endonuclease III DNA Repair Enzyme Protects against Ventilator Induced Lung Injury in Mice.
Lung Neoplasms
Phosphorylation of ribosomal protein S3 and antiapoptotic TRAF2 protein mediates radioresistance in non-small cell lung cancer cells.
RNF138-mediated ubiquitination of rpS3 is required for resistance of glioblastoma cells to radiation-induced apoptosis.
Lymphoma
Different roles of Fpg and Endo III on catechol-induced DNA damage in extended-term cultures of human lymphocytes and L5178Y mouse lymphoma cells.
Melanoma
Enhancement of DNA repair using topical T4 endonuclease V does not inhibit melanoma formation in Cdk4/Tyr-Nras mice following neonatal UVR.
Melanoma chemoprevention.
RPS3 regulates melanoma cell growth and apoptosis by targeting Cyto C/Ca2+/MICU1 dependent mitochondrial signaling.
Treatment of human melanocytes and S91 melanoma cells with the DNA repair enzyme T4 endonuclease V enhances melanogenesis after ultraviolet irradiation.
Neoplasm Metastasis
Changes of Ribosomal Protein S3 Immunoreactivity and Its New Expression in Microglia in the Mice Hippocampus After Lipopolysaccharide Treatment.
Dissociation of MIF-rpS3 complex and sequential NF-?B activation is involved in IR-induced metastatic conversion of NSCLC.
New role of human ribosomal protein S3: Regulation of cell cycle via phosphorylation by cyclin-dependent kinase 2.
Neoplasms
A novel TLR4 binding protein, 40S ribosomal protein S3, has potential utility as an adjuvant in a dendritic cell-based vaccine.
Fucosylated Proteome Profiling Identifies a Fucosylated, Non-Ribosomal, Stress-Responsive Species of Ribosomal Protein S3.
Lung cancer in smoking patients inversely alters the activity of hOGG1 and hNTH1.
Ribosomal protein S3 (rpS3) secreted from various cancer cells is N-linked glycosylated.
Ribosomal protein S3 is secreted as a homodimer in cancer cells.
Sequence specificity of Cr(III)-DNA adduct formation in the p53 gene: NGG sequences are preferential adduct-forming sites.
Strand-specific removal of cyclobutane pyrimidine dimers from the p53 gene in the epidermis of UVB-irradiated hairless mice.
The human endonuclease III enzyme is a relevant target to potentiate cisplatin cytotoxicity in Y-box-binding protein-1 overexpressing tumor cells.
Topical treatment with liposomes containing T4 endonuclease V protects human skin in vivo from ultraviolet-induced upregulation of interleukin-10 and tumor necrosis factor-alpha.
Topical treatment with OGG1 enzyme affects UVB-induced skin carcinogenesis.
Osteosarcoma
Ribosomal protein S3 regulates GLI2-mediated osteosarcoma invasion.
Ovarian Neoplasms
Puncta intended: connecting the dots between autophagy and cell stress networks.
Photosensitivity Disorders
Increased base change mutations at G:C pairs in Escherichia coli deficient in endonuclease III and VIII.
Plague
Glutathionylation of Yersinia pestis LcrV and Its Effects on Plague Pathogenesis.
Reperfusion Injury
A novel mtDNA repair fusion protein attenuates maladaptive remodeling and preserves cardiac function in heart failure.
Sarcoma
Escherichia coli virulence protein NleH1 interaction with the v-Crk sarcoma virus CT10 oncogene-like protein (CRKL) governs NleH1 inhibition of the ribosomal protein S3 (RPS3)/nuclear factor ?B (NF-?B) pathway.
Skin Neoplasms
DNA repair, immunosuppression, and skin cancer.
Effect of topically applied T4 endonuclease V in liposomes on skin cancer in xeroderma pigmentosum: a randomised study. Xeroderma Pigmentosum Study Group.
Measurement of UVB-Induced DNA damage and its consequences in models of immunosuppression.
Topical treatment with OGG1 enzyme affects UVB-induced skin carcinogenesis.
Starvation
Phosphorylated and other modified forms of eukaryotic ribosomal protein S3 analysed by two-dimensional gel electrophoresis.
Sunburn
SKH-1 hairless mice repair UV-induced pyrimidine dimers in epidermal DNA.
Topical treatment with liposomes containing T4 endonuclease V protects human skin in vivo from ultraviolet-induced upregulation of interleukin-10 and tumor necrosis factor-alpha.
Triple Negative Breast Neoplasms
Puncta intended: connecting the dots between autophagy and cell stress networks.
Tuberous Sclerosis
Identification of functional elements in the bidirectional promoter of the mouse Nthl1 and Tsc2 genes.
Ventilator-Induced Lung Injury
Mitochondrial Targeted Endonuclease III DNA Repair Enzyme Protects against Ventilator Induced Lung Injury in Mice.
Xeroderma Pigmentosum
A cell-free assay measuring repair DNA synthesis in human fibroblasts.
DNA repair synthesis in human fibroblasts requires DNA polymerase delta.
Effect of topically applied T4 endonuclease V in liposomes on skin cancer in xeroderma pigmentosum: a randomised study. Xeroderma Pigmentosum Study Group.
Enhanced DNA repair of cyclobutane pyrimidine dimers changes the biological response to UV-B radiation.
Enhancement of ultraviolet-DNA repair in denV gene transfectants and T4 endonuclease V-liposome recipients.
Low-level DNA exchanges in normal human and xeroderma pigmentosum cells after UV irradiation.
Measurement of UVB-Induced DNA damage and its consequences in models of immunosuppression.
Microinjection of T4 endonuclease V produced by a synthetic denV gene stimulates unscheduled DNA synthesis in both xeroderma pigmentosum and normal cells.
Phage T4 endonuclease V stimulates DNA repair replication in isolated nuclei from ultraviolet-irradiated human cells, including xeroderma pigmentosum fibroblasts.
Restoration of ultraviolet-induced unscheduled DNA synthesis of xeroderma pigmentosum cells by the concomitant treatment with bacteriophage T4 endonuclease V and HVJ (Sendai virus).
Specific action of T4 endonuclease V on damaged DNA in xeroderma pigmentosum cells in vivo.
Therapeutics of xeroderma pigmentosum: A PRISMA-compliant systematic review.
[Restoration of ultraviolet-induced unsceduled DNA synthesis of xeroderma pigmentosum cells by insertion of T4 endonuclease V utilizing HVJ (AUTHOR'S TRANSL)]