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Reference on EC 3.1.21.1 - deoxyribonuclease I

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Lehman, I.R.
Bacterial deoxyribonucleases
The Enzymes, 3rd Ed. (Boyer, P. D. , ed. )
4
251-270
1971
Escherichia coli
-
Manually annotated by BRENDA team
Dwyer, A.A.; Huang, A.J.; Pan, C.Q.; Lazarus, R.A.
Expression and characterization of a DNase I-Fc fusion enzyme
J. Biol. Chem.
274
9738-9743
1999
Homo sapiens
Manually annotated by BRENDA team
Felten, C.; Quan, C.P.; Chen, A.B.; Canova-Davis, E.; McNerney, T.; Goetzinger, W.K.; Karger, B.L.
Use of acidic and basic pH and calcium ion addition in the capillary zone electrophoretic characterization of recombinant human deoxyribonuclease, a complex phosphoglycoprotein
J. Chromatogr.
853
295-308
1999
Homo sapiens
Manually annotated by BRENDA team
Chen, C.Y.; Lu, S.C.; Liao, T.H.
Cloning, sequencing and expression of a cDNA encoding bovine pancreatic deoxyribonuclease I in Escherichia coli: purification and characterization of the recombinant enzyme
Gene
206
181-184
1998
Bos taurus
Manually annotated by BRENDA team
Takeshita, H.; Yasuda, T.; Nakajima, T.; Hosomi, O.; Nakashima, Y.; Kishi, K.
Mouse deoxyribonuclease I (DNase I): biochemical and immunological characterization, cDNA structure and tissue distribution
Biochem. Mol. Biol. Int.
42
65-75
1997
Homo sapiens, Mus musculus, Rattus sp.
Manually annotated by BRENDA team
Hsiao, Y.M.; Ho, H.C.; Wang, W.Y.; Tam, M.F.; Liao, T.H.
Purification and characterization of tilapia (Oreochromis mossambicus) deoxyribonuclease I. Primary structure and cDNA sequence
Eur. J. Biochem.
249
786-791
1997
Oreochromis mossambicus
Manually annotated by BRENDA team
Pan, C.Q.; Lazarus, R.A.
Engineering hyperactive variants of human deoxyribonuclease I by altering its functional mechanism
Biochemistry
36
6624-6632
1997
Homo sapiens
Manually annotated by BRENDA team
Takeshita, H.; Yasuda, T.; Nadano, D.; Iida, R.; Kishi, K.
Deoxyribonuclease I from rat urine: affinity purification, characterization, and immunochemical studies
J. Biochem.
118
932-938
1995
Rattus sp.
Manually annotated by BRENDA team
Peitsch, M.C.; Polzar, B.; Stephan, H.; Crompton, T.; MacDonald, H.R.; Mannherz, H.G.; Tschopp, J.
Characterization of the endogenous deoxyribonuclease involved in nuclear DNA degradation during apoptosis (programmed cell death)
EMBO J.
12
371-377
1993
Rattus sp.
Manually annotated by BRENDA team
Chen, L.Y.; Ho, H.C.; Tsai, Y.C.; Liao, T.H.
Deoxyribonuclease of Syncephalastrum racemosum-enzymatic properties and molecular structure
Arch. Biochem. Biophys.
303
51-56
1993
Syncephalastrum racemosum
Manually annotated by BRENDA team
Nakamura, L.T.; Wisnieski, B.J.
Characterization of the deoxyribonuclease activity of diphtheria toxin
J. Biol. Chem.
265
5237-5241
1990
Corynebacterium diphtheriae
Manually annotated by BRENDA team
Yasuda, T.; Awazu, S.; Sato, W.; Iida, R.; Tanaka, Y.; Kishi, K.
Human gentically polymorphic deoxyribonuclease: purification, characterization, and multiplicity of urine deoxyribonuclease I
J. Biochem.
108
393-398
1990
Homo sapiens
Manually annotated by BRENDA team
Bellard, M.; Dretzen, G.; Giangrande, A.; Ramain, P.
Nuclease digestion of transcriptionally active chromatin
Methods Enzymol.
170
317-346
1989
Bos taurus
Manually annotated by BRENDA team
Lu, B.C.; Wong, W.; Fanning, L.; Sakaguchi, K.
Purification and characterization of an endonuclease from fruiting caps of basidiomycete Coprinuns cinereus
Eur. J. Biochem.
174
725-732
1988
Coprinopsis cinerea
Manually annotated by BRENDA team
Cobianchi, F.; Wilson, S.H.
Enzymes for modifying and labeling DNA and RNA
Methods Enzymol.
152
94-110
1987
Bos taurus
Manually annotated by BRENDA team
Paudel, H.K.; Liao, T.H.
Purification, characterization, and the complete amino acid sequence of porcine pancreatic deoxyribonuclease
J. Biol. Chem.
261
16006-16011
1986
Sus scrofa
Manually annotated by BRENDA team
Hibino, Y.; Sugano, N.
The association of a magnesium-dependent endonuclease activity with a nucleosome fraction from rat-liver nuclei
J. Biochem.
98
1583-1590
1985
Rattus sp.
Manually annotated by BRENDA team
Suck, D.; Oefner, C.; Kabsch, W.
Three-dimensional structure of bovine pancreatic DNase I at 2.5 angström resolution
EMBO J.
3
2423-2430
1984
Bos taurus
Manually annotated by BRENDA team
Ito, K.; Minamiura, N.; Yamamato, T.
Human urine DNase I: Immunological identity with human pancreatic DNase I, and enzyme and proteochemical properties of the enzyme
J. Biochem.
95
1399-1406
1984
Homo sapiens
Manually annotated by BRENDA team
Kreuder, V.; Dieckhoff, J.; Sittig, M.; Mannherz, H.G.
Isolation, characterization and crystallization of deoxyribonuclease I from bovine and rat parotid gland and its characterization with rabbit skeletal muscle actin
Eur. J. Biochem.
139
389-400
1984
Bos taurus, Rattus sp.
Manually annotated by BRENDA team
Nagae, S.; Nakayama, J.; Nakano, I.; Anai, M.
Purification and properties of a neutral endodeoxyribonuclease from rat small intestinal mucosa
Biochemistry
21
1339-1344
1982
Rattus sp.
Manually annotated by BRENDA team
Elgin, S.C.R.
DNase I-hypersensitive sites of chromatin
Cell
27
413-415
1981
Gallus gallus, Drosophila melanogaster
Manually annotated by BRENDA team
Anai, M.; Sasaki, M.; Muta, A.; Miyagawa, T.
Purification and properties of a neutral endodeoxyribonuclease from guinea pig epidermis
Biochim. Biophys. Acta
656
183-188
1981
Cavia porcellus
Manually annotated by BRENDA team
Weston, S.A.; Lahm, A.; Suck, D.
X-ray structure of the DNase I-d(GGTATACC)2 complex at 2.3 A resolution
J. Mol. Biol.
226
1237-1256
1992
Bos taurus
Manually annotated by BRENDA team
Moore, S.
Pancreatic DNase
The Enzymes, 3rd Ed. (Boyer, P. D. , ed. )
14
281-296
1981
Bos taurus
-
Manually annotated by BRENDA team
Funkakoshi, A.; Tsubota, Y.; Fujii, K.; Ibayashi, H.; Takagi, Y.
Simple purification and properties of bovine pancreatic deoxyribonuclease I
J. Biochem.
88
1113-1118
1980
Bos taurus
Manually annotated by BRENDA team
Sartin, J.L.; Hugli, T.E.; Liao, T.H.
Reactivity of the tryptophan residues in bovine pancreatic deoxyribonuclease with N-bromosuccinimide
J. Biol. Chem.
255
8633-8637
1980
Bos taurus
Manually annotated by BRENDA team
Hitchcock, S.E.
Actin-deoxyribonuclease I interaction
J. Biol. Chem.
255
5668-5673
1980
Bos taurus
Manually annotated by BRENDA team
Waterborg, J.H.; Kuyper, C.M.A.
Purification and enzymatic characterization of three EndoDNase isoenzymes from Physarum polycephalum
J. Biochem.
87
651-661
1980
Physarum polycephalum
Manually annotated by BRENDA team
Love, J.D.; Hewitt, R.R.
The realtionship between human serum and human pancreatic DNase I
J. Biol. Chem.
254
12588-12594
1979
Homo sapiens
Manually annotated by BRENDA team
Wadano, A.; Hobus, P.A.; Liao, T.H.
Isolation and characterization of multiple forms of ovine pancreatic deoxyribonuclease. Chromatographic behavior of the enzyme on Concanavalin A-agarose and carboxymethylcellulose columns
Biochemistry
18
4124-4129
1979
Ovis aries
Manually annotated by BRENDA team
Lizarraga, B.; Sanchez-Romero, D.; Gil, A.; Melgar, E.
The role of Ca2+ on pH-induced hydrodynamic changes of bovine pancreatic deoxyribonuclease A
J. Biol. Chem.
253
3191-3195
1978
Bos taurus
Manually annotated by BRENDA team
Murai, K.; Yamanaka, M.; Akagi, K.; Anai, M.; Mukai, T.; Omae, T.
Purification and properties of deoxyribonuclease from human urine
Biochim. Biophys. Acta
517
186-194
1978
Homo sapiens
Manually annotated by BRENDA team
Rohr, G.; Mannherz, H.G.
Isolation and characterization of secretory actin-DNase I complex from rat pancreatic juice
Eur. J. Biochem.
89
151-157
1978
Rattus sp.
Manually annotated by BRENDA team
Funakoshi, A.; Tsubota, Y.; Wakasugi, H.; Ibayashi, H.; Takagi, Y.
Purification and properties of human pancreatic deoxyribonuclease I
J. Biochem.
82
1771-1777
1977
Homo sapiens
Manually annotated by BRENDA team
Liao, T.H.
Isolation and characterization of multiple forms of malt deoxyribonuclease
Phytochemistry
16
1469-1474
1977
Hordeum vulgare
-
Manually annotated by BRENDA team
Schaller, K.; Nomura, M.
Colicin E2 is a DNA endonuclease
Proc. Natl. Acad. Sci. USA
73
3989-3993
1976
Escherichia coli
Manually annotated by BRENDA team
Catley, B.J.
Observations on the carbohydrate moiety of bovine pancreatic deoxyribonuclease A
Arch. Biochem. Biophys.
159
214-223
1973
Bos taurus
Manually annotated by BRENDA team
Junowicz, E.; Spencer, J.H.
Studies on bovine pancreatic deoxyribonuclease A 1. Generel properties and activation with different bivalent metals
Biochim. Biophys. Acta
312
72-84
1973
Bos taurus
Manually annotated by BRENDA team
Parisi, E.; De Petrocellin, B.
Properties of a deoxyribonuclease from a nuclear extract of Paracentrotus lividus embryos
Biochem. Biophys. Res. Commun.
49
706-712
1972
Paracentrotus lividus
Manually annotated by BRENDA team
Poulos, T.L.; Price, P.A.
Some effects of calcium ions on the structure of bovine pancreatic deoxyribonuclease A
J. Biol. Chem.
247
2900-2904
1972
Bos taurus
Manually annotated by BRENDA team
Schabort, J.C.; Pitout, M.J.
The relationship between the chemical structure of aflatoxins and their effect on bovine pancreas deoxyribonuclease
Enzymologia
41
201-206
1970
Bos taurus
Manually annotated by BRENDA team
Laskowski, Sr., M.
Deoxyribonuclease I
The Enzymes, 3rd Ed. (Boyer, P. D. , ed. )
4
289-311
1971
Bos taurus
-
Manually annotated by BRENDA team
Yasuda, T.; Takeshita, H.; Ueki, M.; Iida, R.; Nakajima, T.; Mori, S.; Mogi, K.; Kaneko, Y.; Kishi, K.
Tissue-specific in vivo inhibition of DNase I gene expression by somatostatin
Biochem. Biophys. Res. Commun.
283
287-291
2001
Rattus norvegicus (P21704)
Manually annotated by BRENDA team
Ho, T.Y.; Wu, S.L.; Hsiang, C.H.; Chang, T.J.; Hsiang, C.Y.
Identification of a DNA-binding domain and an active-site residue of pseudorabies virus DNase
Biochem. J.
346
441-445
2000
Suid alphaherpesvirus 1
-
Manually annotated by BRENDA team
Yusifov, T.N.; Abduragimov, A.R.; Gasymov, O.K.; Glasgow, B.J.
Endonuclease activity in lipocalins
Biochem. J.
347
815-819
2000
Homo sapiens
-
Manually annotated by BRENDA team
Takeshita, H.; Yasuda, T.; Iida, R.; Nakajima, T.; Mori, S.; Mogi, K.; Kaneko, Y.; Kishi, K.
Amphibian DNases I are characterized by a C-terminal end with a unique, cysteine-rich stretch and by the insertion of a serine residue into the Ca2+-binding site
Biochem. J.
357
473-480
2001
Cynops pyrrhogaster, Cynops pyrrhogaster (Q90W31), Bufo japonicus (Q90WM0), Lithobates catesbeianus (Q90WM1)
Manually annotated by BRENDA team
Shiokawa, D.; Tanuma, S.
Characterization of human DNase I family endonucleases and activation of DNase gamma during apoptosis
Biochemistry
40
143-152
2001
Homo sapiens (P24855), Homo sapiens
Manually annotated by BRENDA team
Iwamori, M.; Suzuki, H.; Kimura, T.; Iwamori, Y.
Shedding of sulfated lipids into gastric fluid and inhibition of pancreatic DNase I by cholesterol sulfate in concert with bile acids
Biochim. Biophys. Acta
1487
268-274
2000
Bos taurus
Manually annotated by BRENDA team
Mori, S.; Yasuda, T.; Takeshita, H.; Nakajima, T.; Nakazato, E.; Mogi, K.; Kaneko, Y.; Kishi, K.
Molecular, biochemical and immunological analyses of porcine pancreatic DNase I
Biochim. Biophys. Acta
1547
275-287
2001
Sus scrofa (P11936), Sus scrofa
Manually annotated by BRENDA team
Yasuda, T.; Takeshita, H.; Iida, R.; Ueki, M.; Nakajima, T.; Kaneko, Y.; Mogi, K.; Kominato, Y.; Kishi, K.
A single amino acid substitution can shift the optimum pH of DNase I for enzyme activity: biochemical and molecular analysis of the piscine DNase I family
Biochim. Biophys. Acta
1672
174-183
2004
Takifugu rubripes, Oreochromis mossambicus (O42446), Oreochromis mossambicus, Pagrus major (Q5KTT0), Pagrus major, Anguilla japonica (Q5KTT1), Anguilla japonica, Cyprinus carpio (Q8JIP7)
Manually annotated by BRENDA team
Yatouji, S.; Liautaud-Roger, F.; Dufer, J.
Nuclear chromatin texture and sensitivity to DNase I in human leukaemic CEM cells incubated with nanomolar okadaic acid
Cell Prolif.
33
51-62
2000
Homo sapiens
Manually annotated by BRENDA team
Desai, N.A.; Shankar, V.
Purification and characterization of the single-strand-specific and guanylic-acid-preferential deoxyribonuclease activity of the extracellular nuclease from Basidiobolus haptosporus
Eur. J. Biochem.
267
5123-5135
2000
Basidiobolus haptosporus
Manually annotated by BRENDA team
Tsutsumi, S.; Kaneko, Y.; Asao, T.; Kuwano, H.; Kudo, S.; Takeshita, H.; Yasuda, T.; Kishi, K.
DNase I is present in the chief cells of human and rat stomachs
Histochem. J.
33
531-535
2002
Homo sapiens, Rattus norvegicus
Manually annotated by BRENDA team
Schernthaner, J.P.; Milne, R.E.; Kaplan, H.
Characterization of a novel insect digestive DNase with a highly alkaline pH optimum
Insect Biochem. Mol. Biol.
32
255-263
2002
Choristoneura fumiferana
Manually annotated by BRENDA team
Mogi, K.; Takeshita, H.; Yasuda, T.; Nakajima, T.; Nakazato, E.; Kaneko, Y.; Itoi, M.; Kishi, K.
Carp hepatopancreatic DNase I: biochemical, molecular, and immunological properties
J. Biochem.
133
377-386
2003
Cyprinus carpio (Q8JIP7), Cyprinus carpio
Manually annotated by BRENDA team
Kaneko, Y.; Takeshita, H.; Mogi, K.; Nakajima, T.; Yasuda, T.; Itoi, M.; Kuwano, H.; Kishi, K.
Molecular, biochemical and immunological analyses of canine pancreatic DNase I
J. Biochem.
134
711-718
2003
Canis lupus familiaris (Q767J3), Canis lupus familiaris
Manually annotated by BRENDA team
Yupsanis, T.; Kefalas, P.S.; Eleftheriou, P.; Kotinis, K.
RNase and DNase activities in the alfalfa and lentil grown in iso-osmotic solutions of NaCl and mannitol
J. Plant Physiol.
158
921-927
2001
Lens culinaris, Medicago sativa
-
Manually annotated by BRENDA team
Hu, C.C.; Lu, S.C.; Cheng, C.C.; Chen, L.H.; Liao, T.H.
Chicken deoxyribonuclease: purification, characterization, gene cloning and gene expression
J. Protein Chem.
22
41-49
2003
Gallus gallus (Q9YGI5), Gallus gallus
Manually annotated by BRENDA team
Chen, C.Y.; Lu, S.C.; Liao, T.H.
The distinctive functions of the two structural calcium atoms in bovine pancreatic deoxyribonuclease
Protein Sci.
11
659-668
2002
Bos taurus
Manually annotated by BRENDA team
Stepinska, U.; Olszanska, B.
Detection of deoxyribonuclease I and II activities in Japanese quail oocytes
Zygote
9
1-7
2001
Coturnix japonica
Manually annotated by BRENDA team
Napirei, M.; Wulf, S.; Eulitz, D.; Mannherz, H.G.; Kloeckl, T.
Comparative characterization of rat deoxyribonuclease 1 (Dnase1) and murine deoxyribonuclease 1-like 3 (Dnase1l3)
Biochem. J.
389
355-364
2005
Mus musculus, Rattus norvegicus (P21704)
Manually annotated by BRENDA team
Chen, W.J.; Huang, P.T.; Liu, J.; Liao, T.H.
Involvement of the N- and C-terminal fragments of bovine pancreatic deoxyribonuclease in active protein folding
Biochemistry
43
10653-10663
2004
Bos taurus (P00639), Bos taurus
Manually annotated by BRENDA team
Van den Bremer, E.T.J.; Keeble, A.H.; Visser, A.J.W.G.; Van Hoek, A.; Kleanthous, C.; Heck, A.J.R.; Jiskoot, W.
Ligand-induced changes in the conformational dynamics of a bacterial cytotoxic endonuclease
Biochemistry
43
4347-4355
2004
Escherichia coli
Manually annotated by BRENDA team
Babina, S.E.; Kanyshkova, T.G.; Buneva, V.N.; Nevinsky, G.A.
Lactoferrin is the major deoxyribonuclease of human milk
Biochemistry (Moscow)
69
1006-1015
2004
Homo sapiens
Manually annotated by BRENDA team
Baranovskii, A.G.; Buneva, V.N.; Nevinsky, G.A.
Human deoxyribonucleases
Biochemistry (Moscow)
69
587-601
2004
Homo sapiens
Manually annotated by BRENDA team
Fujihara, J.; Hieda, Y.; Xue, Y.; Nakagami, N.; Takayama, K.; Kataoka, K.; Takeshita, H.
One-step purification of mammalian deoxyribonucleases I and differences among pancreas, parotid, and pancreas-parotid (mixed) types based on species- and organ-specific N-linked glycosylation
Biochemistry (Moscow)
71 Suppl 1
S65-70
2006
Oryctolagus cuniculus, Rattus norvegicus, Sus scrofa
Manually annotated by BRENDA team
van den Bremer, E.T.J.; Keeble, A.H.; Kleanthous, C.; Heck, A.J.R.
Metal induced selectivity in phosphate ion binding in E9 DNase
Chem. Commun. (Camb.)
9
1137-1139
2005
Escherichia coli
-
Manually annotated by BRENDA team
Kawai, Y.; Yoshida, M.; Arakawa, K.; Kumamoto, T.; Morikawa, N.; Masamura, K.; Tada, H.; Ito, S.; Hoshizaki, H.; Oshima, S.; Taniguchi, K.; Terasawa, H.; Miyamori, I.; Kishi, K.; Yasuda, T.
Diagnostic use of serum deoxyribonuclease I activity as a novel early-phase marker in acute myocardial infarction
Circulation
109
2398-2400
2004
Homo sapiens
Manually annotated by BRENDA team
Krawczenko, A.; Ciszak, L.; Malicka-Blaszkiewicz, M.
Carp liver DNase - isolation, further characterization and interaction with endogenous actin
Comp. Biochem. Physiol. B
140B
141-151
2005
Cyprinus carpio
-
Manually annotated by BRENDA team
Fujihara, J.; Hieda, Y.; Xue, Y.; Nakagami, N.; Imamura, S.; Takayama, K.; Kataoka, K.; Takeshita, H.
Actin-inhibition and folding of vertebrate deoxyribonuclease I are affected by mutations at residues 67 and 114
Comp. Biochem. Physiol. B
143
70-75
2006
Elaphe quadrivirgata, Gloydius blomhoffii, Homo sapiens (P24855), Homo sapiens, Sus scrofa (P11936), Sus scrofa, Xenopus laevis
Manually annotated by BRENDA team
Hsia, K.C.; Li, C.L.; Yuan, H.S.
Structural and functional insight into sugar-nonspecific nucleases in host defense
Curr. Opin. Struct. Biol.
15
126-134
2005
Escherichia coli, Vibrio cholerae serotype O1
Manually annotated by BRENDA team
Yasuda, T.; Iida, R.; Ueki, M.; Kominato, Y.; Nakajima, T.; Takeshita, H.; Kobayashi, T.; Kishi, K.
Molecular evolution of shark and other vertebrate DNases I
Eur. J. Biochem.
271
4428-4435
2004
Heterodontus japonicus (Q5R2I2), Heterodontus japonicus, Triakis scyllium (Q5R2I3), Triakis scyllium
Manually annotated by BRENDA team
Oliveri, M.; Daga, A.; Lunardi, C.; Navone, R.; Millo, R.; Puccetti, A.
DNase I behaves as a transcription factor which modulates fas expression in human cells
Eur. J. Immunol.
34
273-279
2004
Homo sapiens
Manually annotated by BRENDA team
Fontaine, M.C.; Perez-Casal, J.; Willson, P.J.
Investigation of a novel DNase of Streptococcus suis serotype 2
Infect. Immun.
72
774-781
2004
Streptococcus suis
Manually annotated by BRENDA team
Napirei, M.; Gultekin, A.; Kloeckl, T.; Moroy, T.; Frostegard, J.; Mannherz, H.G.
Systemic lupus-erythematosus: deoxyribonuclease 1 in necrotic chromatin disposal
Int. J. Biochem. Cell Biol.
38
297-306
2006
Mus musculus
Manually annotated by BRENDA team
O'Rourke, E.J.; Pinto, A.V.; Petroni, E.A.; Tolmasky, M.E.; Ielpi, L.
Evidence for the active role of a novel nuclease from Helicobacter pylori in the horizontal transfer of genetic information
J. Bacteriol.
186
2586-2593
2004
Helicobacter pylori
Manually annotated by BRENDA team
Anindya, R.; Savithri, H.S.
Potyviral NIa proteinase, a proteinase with novel deoxyribonuclease activity
J. Biol. Chem.
279
32159-32169
2004
Potyvirus sp.
Manually annotated by BRENDA team
Bencina, M.; Bencina, K.; Strancar, A.; Podgornik, A.
Immobilization of deoxyribonuclease via epoxy groups of methacrylate monoliths
J. Chromatogr. A
1065
83-91
2005
Bos taurus
Manually annotated by BRENDA team
Coulon, S.; Gaillard, P.h.L.; Chahwan, C.; McDonald, W.H.; Yates, J.R.3rd.; Russell, P.
Slx1-Slx4 are subunits of a structure-specific endonuclease that maintains ribosomal DNA in fission yeast
Mol. Biol. Cell
15
71-80
2004
Schizosaccharomyces pombe
Manually annotated by BRENDA team
De Maria, A.; Arruti, C.
DNase I and fragmented chromatin during nuclear degradation in adult bovine lens fibers
Mol. Vis.
10
74-82
2004
Bos taurus
Manually annotated by BRENDA team
Sumby, P.; Barbian, K.D.; Gardner, D.J.; Whitney, A.R.; Welty, D.M.; Long, R.D.; Bailey, J.R.; Parnell, M.J.; Hoe, N.P.; Adams, G.G.; DeLeo, F.R.; Musser, J.M.
Extracellular deoxyribonuclease made by group A Streptococcus assists pathogenesis by enhancing evasion of the innate immune response
Proc. Natl. Acad. Sci. USA
102
1679-1684
2005
Streptococcus pyogenes
Manually annotated by BRENDA team
Patil, N.S.; Deshmukh, S.S.; Shankar, V.
Extracellular nuclease from a thermophile, Streptomyces thermonitrificans: production, purification and partial characterization of - double strand preferential - deoxyribonuclease activity
Process Biochem.
40
1271-1278
2004
Streptomyces thermovulgaris
-
Manually annotated by BRENDA team
Chen, W.J.; Lee, I.S.; Chen, C.Y.; Liao, T.H.
Biological functions of the disulfides in bovine pancreatic deoxyribonuclease
Protein Sci.
13
875-883
2004
Bos taurus
Manually annotated by BRENDA team
Chhabra, D.; Nosworthy, N.J.; dos Remedios, C.G.
The N-terminal fragment of gelsolin inhibits the interaction of DNase I with isolated actin, but not with the cofilin-actin complex
Proteomics
5
3131-3136
2005
Homo sapiens
Manually annotated by BRENDA team
Eulitz, D.; Mannherz, H.G.
Inhibition of deoxyribonuclease I by actin is to protect cells from premature cell death
Apoptosis
12
1511-1521
2007
Mus musculus (P49183)
Manually annotated by BRENDA team
Chen, W.J.; Lo, T.; Lai, Y.S.; Huang, P.T.; Lin, C.C.; Liao, T.H.
Construction and characterization of a bifunctional enzyme with deoxyribonuclease I and thioredoxin-like activities
Biochem. Biophys. Res. Commun.
356
750-755
2007
Bos taurus (P00639), Bos taurus
Manually annotated by BRENDA team
Ueki, M.; Takeshita, H.; Fujihara, J.; Ueta, G.; Nakajima, T.; Kominato, Y.; Kishi, K.; Iida, R.; Yasuda, T.
Susceptibility of mammalian deoxyribonucleases I (DNases I) to proteolysis by proteases and its relationships to tissue distribution: Biochemical and molecular analysis of equine DNase I
Comp. Biochem. Physiol. B
148B
93-102
2007
Equus caballus (Q4AEE3)
-
Manually annotated by BRENDA team
Lichtinghagen, R.
Determination of Pulmozyme (dornase alpha) stability using a kinetic colorimetric DNase I activity assay
Eur. J. Pharm. Biopharm.
63
365-368
2006
Homo sapiens
Manually annotated by BRENDA team
Ye, W.; Mairet-Coello, G.; DiCicco-Bloom, E.
DNAse I pre-treatment markedly enhances detection of nuclear cyclin-dependent kinase inhibitor p57Kip2 and BrdU double immunostaining in embryonic rat brain
Histochem. Cell Biol.
127
195-203
2007
Rattus norvegicus
Manually annotated by BRENDA team
Cherepanova, A.; Tamkovich, S.; Pyshnyi, D.; Kharkova, M.; Vlassov, V.; Laktionov, P.
Immunochemical assay for deoxyribonuclease activity in body fluids
J. Immunol. Methods
325
96-103
2007
Homo sapiens
Manually annotated by BRENDA team
Fujihara, J.; Takatsuka, H.; Kataoka, K.; Xue, Y.; Takeshita, H.
Two deoxyribonuclease I gene polymorphisms and correlation between genotype and its activity in Japanese population
Leg. Med.
9
233-236
2007
Homo sapiens
Manually annotated by BRENDA team
Kodama, Y.; Nagaya, S.; Shinmyo, A.; Kato, K.
Mapping and characterization of DNase I hypersensitive sites in Arabidopsis chromatin
Plant Cell Physiol.
48
459-470
2007
Arabidopsis thaliana
Manually annotated by BRENDA team
Zannoni, A.; Spinaci, M.; Bernardini, C.; Bacci, M.L.; Seren, E.; Mattioli, M.; Forni, M.
DNase I activity in pig MII oocytes: implications in transgenesis
Reproduction
131
461-468
2006
Sus scrofa (P11936), Sus scrofa
Manually annotated by BRENDA team
Sato, S.; Fujita, K.; Kanazawa, M.; Mukumoto, K.; Ohtsuka, K.; Waki, M.; Takenaka, S.
Electrochemical assay for deoxyribonuclease I activity
Anal. Biochem.
381
233-239
2008
Bos taurus
Manually annotated by BRENDA team
Fukano, H.; Suzuki, Y.
Enzymatic conversion of long DNA to small DNA fragments for the construction of short hairpin RNA expression libraries
Anal. Biochem.
385
80-84
2009
Homo sapiens
Manually annotated by BRENDA team
Martínez Valle, F.; Balada, E.; Ordi-Ros, J.; Vilardell-Tarres, M.
DNase 1 and systemic lupus erythematosus
Autoimmun. Rev.
7
359-363
2008
Bos taurus, Homo sapiens, Mus musculus
Manually annotated by BRENDA team
N'soukpoé-Kossi, C.N.; Diamantoglou, S.; Tajmir-Riahi, H.A.
DNase I - DNA interaction alters DNA and protein conformations
Biochem. Cell Biol.
86
244-250
2008
Bos taurus
Manually annotated by BRENDA team
Mannherz, H.G.; Ballweber, E.; Hegyi, G.; Goody, R.S.
Cross-linked long-pitch actin dimer forms stoichiometric complexes with gelsolin segment 1 and/or deoxyribonuclease I that nonproductively interact with myosin subfragment 1
Biochemistry
47
9335-9343
2008
Bos taurus
Manually annotated by BRENDA team
Fujihara, J.; Yasuda, T.; Kunito, T.; Fujii, Y.; Takatsuka, H.; Moritani, T; Takeshita, H.
Two N-linked glycosylation sites (Asn18 and Asn106) are both required for full enzymatic activity, thermal stability, and resistance to proteolysis in mammalian deoxyribonuclease I
Biosci. Biotechnol. Biochem.
72
3197-3205
2008
Bos taurus, Homo sapiens (P24855), Homo sapiens, Equus caballus (Q4AEE3), Equus caballus
Manually annotated by BRENDA team
Shi, B.; Guo, X.; Wu, T.; Sheng, S.; Wang, J.; Skogerbo, G.; Zhu, X.; Chen, R.
Genome-scale identification of Caenorhabditis elegans regulatory elements by tiling-array mapping of DNase I hypersensitive sites
BMC Genomics
10
92
2009
Caenorhabditis elegans, Caenorhabditis elegans N2
Manually annotated by BRENDA team
Tammaro, S.; Simoniello, P.; Filosa, S.; Motta, C.M.
cGnRH II involvement in pyriform cell apoptosis
Cell Tissue Res.
332
337-347
2008
Podarcis siculus
Manually annotated by BRENDA team
Takeshita, H.; Soejima, M.; Koda, Y.; Yasuda, T.; Takatsuka, H.; Fujihara, J.
Gln222Arg (A2317G) polymorphism in the deoxyribonuclease I gene exhibits ethnic and functional differences
Clin. Chem. Lab. Med.
47
51-55
2009
Homo sapiens
Manually annotated by BRENDA team
Elkordy, A.A.; Forbes, R.T.; Barry, B.W.
Study of protein conformational stability and integrity using calorimetry and FT-Raman spectroscopy correlated with enzymatic activity
Eur. J. Pharm. Sci.
33
177-190
2008
Bos taurus
Manually annotated by BRENDA team
Napirei, M.; Ludwig, S.; Mezrhab, J.; Klöckl, T.; Mannherz, H.G.
Murine serum nucleases - contrasting effects of plasmin and heparin on the activities of DNase1 and DNase1-like 3 (DNase1/3)
FEBS J.
276
1059-1073
2009
Homo sapiens, Mus musculus (O55070), Mus musculus, Mus musculus C57BL/6 (O55070)
Manually annotated by BRENDA team
Choi, C.H.; Hyun, S.H.; Kim, J.; Lee, Y.C.; Seol, S.Y.; Cho, D.T.; Lee, J.C.
Nuclear translocation and DNAse I-like enzymatic activity of Acinetobacter baumannii outer membrane protein A
FEMS Microbiol. Lett.
288
62-67
2008
Acinetobacter baumannii, Acinetobacter baumannii ATCC 19606T
Manually annotated by BRENDA team
DiRienzo, J.M.; Cao, L.; Volgina, A.; Bandelac, G.; Korostoff, J..
Functional and structural characterization of chimeras of a bacterial genotoxin and human type I DNAse
FEMS Microbiol. Lett.
291
222-231
2009
Bos taurus (P00639), Homo sapiens (P24855), Homo sapiens
Manually annotated by BRENDA team
Boyano, M.D.; Andollo, N.; Zalduendo, M.M.; Aréchaga, J.
Imprinting of mammalian male gametes is gene specific and does not occur at a single stage of differentiation
Int. J. Dev. Biol.
52
1105-1111
2008
Mus musculus
Manually annotated by BRENDA team
Boyano, M.D.; Andollo, N.; Zalduendo, M.M.; Aréchaga, J.
Association between practice patterns and body mass index percentile in infants and young children with cystic fibrosis
J. Cyst. Fibros.
7
385-390
2008
Homo sapiens
Manually annotated by BRENDA team
Krasnorutskii, M.A.; Buneva, V.N.; Nevinsky, G.A.
Immunization of rabbits with DNase I produces polyclonal antibodies with DNase and RNase activities
J. Mol. Recognit.
21
233-242
2008
Bos taurus, Homo sapiens
Manually annotated by BRENDA team
N'soukpoe-Kossi, C.N.; Tajmir-Riahi, H.A.
DNase I-tRNA interaction
Oligonucleotides
18
65-72
2008
Bos taurus
Manually annotated by BRENDA team
Chen, W.J.; Liao, T.H.
2-Nitro-5-thiosulfobenzoic acid as a novel inhibitor specific for deoxyribonuclease I
Protein J.
27
240-246
2008
Bos taurus, Rattus norvegicus
Manually annotated by BRENDA team
Chen, W.J.; Huang, P.T.; Cheng, Y.C.; Liao, T.H.
Putative secondary active site of bovine pancreatic deoxyribonuclease I
Protein Pept. Lett.
15
640-646
2008
Bos taurus
Manually annotated by BRENDA team
Hirano, J.; Miyamoto, K.; Ohta, H.
Cytological investigation of Haplopappus gracilis (Nutt.) Gray: 5-methylcytosine-rich regions, fluorochrome banding and chromatin sensitivity to DNase I digestion
Protoplasma
233
107-113
2008
Xanthisma gracile
Manually annotated by BRENDA team
Zhao, W.; Lam, J.C.; Chiuman, W.; Brook, M.A.; Li, Y.
Enzymatic cleavage of nucleic acids on gold nanoparticles: a generic platform for facile colorimetric biosensors
Small
4
810-816
2008
Homo sapiens
Manually annotated by BRENDA team
Wahlberg, K.; Jiang, J.; Rooks, H.; Jawaid, K.; Matsuda, F.; Yamaguchi, M.; Lathrop, M.; Thein, S.L.; Best, S.
The HBS1L-MYB intergenic interval associated with elevated HbF levels shows characteristics of a distal regulatory region in erythroid cells
Blood
114
1254-1262
2009
Homo sapiens
Manually annotated by BRENDA team
Syed, S.H.; Boulard, M.; Shukla, M.S.; Gautier, T.; Travers, A.; Bednar, J.; Faivre-Moskalenko, C.; Dimitrov, S.; Angelov, D.
The incorporation of the novel histone variant H2AL2 confers unusual structural and functional properties of the nucleosome
Nucleic Acids Res.
37
4684-4695
2009
Mus musculus
Manually annotated by BRENDA team
Yasuda, T.; Ueki, M.; Takeshita, H.; Fujihara, J.; Kimura-Kataoka, K.; Iida, R.; Tsubota, E.; Soejima, M.; Koda, Y.; Kato, H.; Panduro, A.
A biochemical and genetic study on all non-synonymous single nucleotide polymorphisms of the gene encoding human deoxyribonuclease I potentially relevant to autoimmunity
Int. J. Biochem. Cell Biol.
42
1216-1225
2010
Homo sapiens (P24855), Homo sapiens
Manually annotated by BRENDA team
Stefan, A.; Conti, M.; Rubboli, D.; Ravagli, L.; Presta, E.; Hochkoeppler, A.
Overexpression and purification of the recombinant diphtheria toxin variant CRM197 in Escherichia coli
J. Biotechnol.
156
245-252
2010
Corynebacterium diphtheriae
Manually annotated by BRENDA team
Heddi, B.; Abi-Ghanem, J.; Lavigne, M.; Hartmann, B.
Sequence-dependent DNA flexibility mediates DNase I cleavage
J. Mol. Biol.
395
123-133
2010
Bos taurus
Manually annotated by BRENDA team
Gueroult, M.; Picot, D.; Abi-Ghanem, J.; Hartmann, B.; Baaden, M.
How cations can assist DNase I in DNA binding and hydrolysis
PLoS Comput. Biol.
6
e1001000
2010
Bos taurus
Manually annotated by BRENDA team
Zhou, Z.; Zhu, C.; Ren, J.; Dong, S.
A graphene-based real-time fluorescent assay of deoxyribonuclease I activity and inhibition
Anal. Chim. Acta
740
88-92
2012
Bos taurus
Manually annotated by BRENDA team
Dou, Y.; Yang, X.
Novel high-sensitive fluorescent detection of deoxyribonuclease I based on DNA-templated gold/silver nanoclusters
Anal. Chim. Acta
784
53-58
2013
Homo sapiens
Manually annotated by BRENDA team
Parsiegla, G.; Noguere, C.; Santell, L.; Lazarus, R.A.; Bourne, Y.
The structure of human DNase I bound to magnesium and phosphate ions points to a catalytic mechanism common to members of the DNase I-like superfamily
Biochemistry
51
10250-10258
2012
Homo sapiens (P24855), Homo sapiens
Manually annotated by BRENDA team
Skiljevic, D.; Jeremic, I.; Nikolic, M.; Andrejevic, S.; Sefik-Bukilica, M.; Stojimirovic, B.; Bonaci-Nikolic, B.
Serum DNase I activity in systemic Lupus erythematosus: correlation with immunoserological markers, the disease activity and organ involvement
Clin. Chem. Lab. Med.
51
1083-1091
2013
Homo sapiens
Manually annotated by BRENDA team
Nguyen, U.T.; Burrows, L.L.
DNase I and proteinase K impair Listeria monocytogenes biofilm formation and induce dispersal of pre-existing biofilms
Int. J. Food Microbiol.
187
26-32
2014
Bos taurus
Manually annotated by BRENDA team
Zhu, B.; Gong, Y.; Chen, P.; Zhang, H.; Zhao, T.; Li, P.
Increased DNase I activity in diabetes might be associated with injury of pancreas
Mol. Cell. Biochem.
393
23-32
2014
Homo sapiens, Rattus norvegicus
Manually annotated by BRENDA team
Ershova, E.; Sergeeva, V.; Klimenko, M.; Avetisova, K.; Klimenko, P.; Kostyuk, E.; Veiko, N.; Veiko, R.; Izevskaya, V.; Kutsev, S.; Kostyuk, S.
Circulating cell-free DNA concentration and DNase I activity of peripheral blood plasma change in case of pregnancy with intrauterine growth restriction compared to normal pregnancy
Biomed. Rep.
7
319-324
2017
Homo sapiens (P24855), Homo sapiens
Manually annotated by BRENDA team
Ts Mavrova, A.; Dimov, S.; Yancheva, D.; Kolarevic, A.; Ilic, B.S.; Kocic, G.; Smelcerovic, A.
Synthesis and DNase I inhibitory properties of some 5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidines
Bioorg. Chem.
80
693-705
2018
Bos taurus (P00639), Bos taurus
Manually annotated by BRENDA team
Wilken, M.S.; Brzezinski, J.A.; La Torre, A.; Siebenthall, K.; Thurman, R.; Sabo, P.; Sandstrom, R.S.; Vierstra, J.; Canfield, T.K.; Hansen, R.S.; Bender, M.A.; Stamatoyannopoulos, J.; Reh, T.A.
DNase I hypersensitivity analysis of the mouse brain and retina identifies region-specific regulatory elements
Epigenetics Chromatin
8
8
2015
Mus musculus (P49183), Mus musculus
Manually annotated by BRENDA team
Brown, H.L.; Hanman, K.; Reuter, M.; Betts, R.P.; van Vliet, A.H.
Campylobacter jejuni biofilms contain extracellular DNA and are sensitive to DNase I treatment
Front. Microbiol.
6
699
2015
Bos taurus (P00639)
Manually annotated by BRENDA team
Das, T.; Simone, M.; Ibugo, A.I.; Witting, P.K.; Manefield, M.; Manos, J.
Glutathione enhances antibiotic efficiency and effectiveness of DNase I in disrupting Pseudomonas aeruginosa biofilms while also inhibiting pyocyanin activity, thus facilitating restoration of cell enzymatic activity, confluence and viability
Front. Microbiol.
8
2429
2017
Bos taurus (P00639)
Manually annotated by BRENDA team
Alexeeva, L.; Patutina, O.; Senkova, A.; Zenkova, M.; Mironova, N.
Inhibition of invasive properties of murine melanoma by bovine pancreatic DNase I in vitro and in vivo
Mol. Biol.
51
562-570
2017
Bos taurus (P00639), Bos taurus
Manually annotated by BRENDA team