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Arthritis
Cyclooxygenase-2 inhibition reverts the decrease in adiponectin levels and attenuates the loss of white adipose tissue during chronic inflammation.
Atherosclerosis
Abrogation of neutral cholesterol ester hydrolytic activity causes adrenal enlargement.
Atherosclerosis
Elimination of cholesterol ester from macrophage foam cells by adenovirus-mediated gene transfer of hormone-sensitive lipase.
Atherosclerosis
Paradoxical effect on atherosclerosis of hormone-sensitive lipase overexpression in macrophages.
Atherosclerosis
Reduced atherosclerosis in hormone-sensitive lipase transgenic mice overexpressing cholesterol acceptors.
Breast Neoplasms
Fatty acid-binding protein 5 (FABP5) promotes lipolysis of lipid droplets, de novo fatty acid (FA) synthesis and activation of nuclear factor-kappa B (NF-?B) signaling in cancer cells.
Carcinoma, Hepatocellular
?-Adrenergic induction of lipolysis in hepatocytes is inhibited by ethanol exposure.
Carcinoma, Hepatocellular
Comparison of the changes in lipid metabolism between hepatoma-bearing and lipopolysaccharide-treated rats.
Carcinoma, Hepatocellular
Effects of sulfur amino acids, L: -methionine, L: -cystine and L: -cysteine on lipoprotein lipase and hormone-sensitive lipase in differentiated mouse 3T3-L1 adipocytes.
Carcinoma, Hepatocellular
Metabolic characteristics of a human hepatoma cell line stably transfected with hormone-sensitive lipase.
Cardiomyopathies
Inborn errors of cytoplasmic triglyceride metabolism.
Cardiovascular Diseases
Effect of Bariatric Weight Loss on the Adipose Lipolytic Transcriptome in Obese Humans.
Colonic Neoplasms
Expression of hormone-sensitive lipase in the human colon adenocarcinoma cell line HT29.
Dandruff
Secreted lipases from Malassezia globosa: recombinant expression and determination of their substrate specificities.
Dermatitis
Secreted lipases from Malassezia globosa: recombinant expression and determination of their substrate specificities.
Diabetes Mellitus
Bioactive compounds in plant materials for the prevention of diabetesand obesity.
Diabetes Mellitus
Cyclipostins, novel hormone-sensitive lipase inhibitors from Streptomyces sp. DSM 13381. II. Isolation, structure elucidation and biological properties.
Diabetes Mellitus
Hormone-sensitive lipase is reduced in the adipose tissue of patients with type 2 diabetes mellitus: influence of IL-6 infusion.
Diabetes Mellitus
The putative role of the hormone-sensitive lipase gene in the pathogenesis of Type II diabetes mellitus and abdominal obesity.
Diabetes Mellitus, Type 2
Bioactive compounds in plant materials for the prevention of diabetesand obesity.
Diabetes Mellitus, Type 2
Downregulation of islet hormone-sensitive lipase during long-term high-fat feeding.
Diabetes Mellitus, Type 2
Effects of monounsaturated vs. saturated fat on postprandial lipemia and adipose tissue lipases in type 2 diabetes.
Diabetes Mellitus, Type 2
Hormone-sensitive lipase is reduced in the adipose tissue of patients with type 2 diabetes mellitus: influence of IL-6 infusion.
Diabetes Mellitus, Type 2
Human hormone-sensitive lipase: genetic mapping, identification of a new dinucleotide repeat, and association with obesity and NIDDM.
Diabetes Mellitus, Type 2
Null mutation in hormone-sensitive lipase gene and risk of type 2 diabetes.
Diabetes Mellitus, Type 2
Specific inhibition of hormone-sensitive lipase improves lipid profile while reducing plasma glucose.
Diabetes Mellitus, Type 2
Synthesis and structure-activity relationship for a novel class of potent and selective carbamoyl-triazole based inhibitors of hormone sensitive lipase.
Diabetes Mellitus, Type 2
[Multivariate logistic regression analysis on the risk factors of type 2 diabetes mellitus]
Diabetic Cardiomyopathies
Cardiac overexpression of hormone-sensitive lipase inhibits myocardial steatosis and fibrosis in streptozotocin diabetic mice.
Dyslipidemias
[Diagnosis of Secondary Hyperlipidemia due to Diabetes].
Epilepsy
Fold prediction and comparative modeling of Bdm1: a probable alpha/beta hydrolase associated with hot water epilepsy.
Fatty Liver
Adipose tissue deficiency of hormone-sensitive lipase causes fatty liver in mice.
Fatty Liver
Advanced lipodystrophy reverses fatty liver in mice lacking adipocyte hormone-sensitive lipase.
Fatty Liver
Risk interaction of obesity, insulin resistance and hormone-sensitive lipase promoter polymorphisms (LIPE-60 C > G) in the development of fatty liver.
Glucose Intolerance
Adipose tissue metabolism in obesity: lipase action in vivo before and after a mixed meal.
Glucose Intolerance
Synthesis and structure-activity relationship for a novel class of potent and selective carbamoyl-triazole based inhibitors of hormone sensitive lipase.
HIV-Associated Lipodystrophy Syndrome
Effect of extended-release niacin on hormone-sensitive lipase and lipoprotein lipase in patients with HIV-associated lipodystrophy syndrome.
hormone-sensitive lipase deficiency
Hormone-sensitive lipase deficiency affects the expression of SR-BI, LDLr, and ABCA1 receptors/transporters involved in cellular cholesterol uptake and efflux and disturbs fertility in mouse testis.
hormone-sensitive lipase deficiency
Hormone-sensitive lipase deficiency alters gene expression and cholesterol content of mouse testis.
hormone-sensitive lipase deficiency
Hormone-sensitive lipase deficiency disturbs lipid composition of plasma membrane microdomains from mouse testis.
hormone-sensitive lipase deficiency
Hormone-sensitive lipase deficiency disturbs the fatty acid composition of mouse testis.
hormone-sensitive lipase deficiency
Hormone-sensitive lipase deficiency in humans.
hormone-sensitive lipase deficiency
Hormone-sensitive lipase deficiency in mice causes diglyceride accumulation in adipose tissue, muscle, and testis.
hormone-sensitive lipase deficiency
Hormone-sensitive lipase deficiency in mice causes lipid storage in the adrenal cortex and impaired corticosterone response to corticotropin stimulation.
hormone-sensitive lipase deficiency
Hormone-sensitive lipase deficiency in mice changes the plasma lipid profile by affecting the tissue-specific expression pattern of lipoprotein lipase in adipose tissue and muscle.
hormone-sensitive lipase deficiency
Hormone-sensitive lipase deficiency in mouse islets abolishes neutral cholesterol ester hydrolase activity but leaves lipolysis, acylglycerides, fat oxidation, and insulin secretion intact.
hormone-sensitive lipase deficiency
Hormone-sensitive lipase deficiency suppresses insulin secretion from pancreatic islets of Lep ob/ob mice.
hormone-sensitive lipase deficiency
Infertility and testicular defects in hormone-sensitive lipase-deficient mice.
hormone-sensitive lipase deficiency
Letting lipids go: hormone-sensitive lipase.
hormone-sensitive lipase deficiency
The adipose tissue phenotype of hormone-sensitive lipase deficiency in mice.
Hyperglycemia
FNDC5 overexpression and irisin ameliorate glucose/lipid metabolic derangements and enhance lipolysis in obesity.
Hyperinsulinism
Chronic exposure of rat fat cells to insulin enhances lipolysis and activation of partially purified hormone-sensitive lipase.
Hyperinsulinism
FNDC5 overexpression and irisin ameliorate glucose/lipid metabolic derangements and enhance lipolysis in obesity.
Hyperinsulinism
Molecular evidence supporting the portal theory: a causative link between visceral adiposity and hepatic insulin resistance.
Hyperinsulinism
Muscle type-dependent responses to insulin in intramyocellular triglyceride turnover in obese rats.
Hyperlipidemia, Familial Combined
Adipose tissue lipoprotein lipase and hormone-sensitive lipase. Contrasting findings in familial combined hyperlipidemia and insulin resistance syndrome.
Hyperlipidemia, Familial Combined
C3, hormone-sensitive lipase, and peroxisome proliferator-activated receptor gamma expression in adipose tissue of familial combined hyperlipidemia patients.
Hyperlipidemia, Familial Combined
In vivo modulation of plasma free fatty acids in patients with familial combined hyperlipidemia using lipid-lowering medication.
Hyperlipidemias
Adipose tissue lipoprotein lipase and hormone-sensitive lipase. Contrasting findings in familial combined hyperlipidemia and insulin resistance syndrome.
Hyperlipidemias
C3, hormone-sensitive lipase, and peroxisome proliferator-activated receptor gamma expression in adipose tissue of familial combined hyperlipidemia patients.
Hyperlipidemias
Effects of monounsaturated vs. saturated fat on postprandial lipemia and adipose tissue lipases in type 2 diabetes.
Hyperlipidemias
Effects of sulfur amino acids, L: -methionine, L: -cystine and L: -cysteine on lipoprotein lipase and hormone-sensitive lipase in differentiated mouse 3T3-L1 adipocytes.
Hyperlipidemias
FNDC5 overexpression and irisin ameliorate glucose/lipid metabolic derangements and enhance lipolysis in obesity.
Hyperlipidemias
In vivo modulation of plasma free fatty acids in patients with familial combined hyperlipidemia using lipid-lowering medication.
Hyperthyroidism
Adrenergic binding sites and enzyme activities in the heart of hyperthyroid rats.
Hyperthyroidism
Catecholamine-induced adipocyte lipolysis in human hyperthyroidism.
Hyperthyroidism
The atrial natriuretic peptide- and catecholamine-induced lipolysis and expression of related genes in adipose tissue in hypothyroid and hyperthyroid patients.
Hypertriglyceridemia
Inborn errors of cytoplasmic triglyceride metabolism.
Hypothyroidism
Adrenergic regulation of lipolysis in fat cells from hyperthyroid and hypothyroid patients.
Ichthyosis
Inborn errors of cytoplasmic triglyceride metabolism.
Infections
A secreted lipase of Fusarium graminearum is a virulence factor required for infection of cereals.
Infections
Clofazimine modulates the expression of lipid metabolism proteins in Mycobacterium leprae-infected macrophages.
Infections
Legionella pneumophila genes that encode lipase and phospholipase C activities.
Infections
Overexpression of Rv3097c in Mycobacterium bovis BCG abolished the efficacy of BCG vaccine to protect against Mycobacterium tuberculosis infection in mice.
Infections
RAS2 regulates growth and pathogenesis in Fusarium graminearum.
Infections
Resistance of callose synthase activity to free fatty acid inhibition as an indicator of Fusarium head blight resistance in wheat.
Infections
Secretome analysis reveals an Arabidopsis lipase involved in defense against Alternaria brassicicola.
Infections
The secreted lipase FGL1 is sufficient to restore the initial infection step to the apathogenic Fusarium graminearum MAP kinase disruption mutant ?gpmk1
Infertility
The N-terminal His-tag affects the triglyceride lipase activity of hormone-sensitive lipase in testis.
Infertility, Male
Targeted disruption of hormone-sensitive lipase results in male sterility and adipocyte hypertrophy, but not in obesity.
Infertility, Male
The testicular form of hormone-sensitive lipase HSLtes confers rescue of male infertility in HSL-deficient mice.
Influenza, Human
Hepatic steatosis during convalescence from influenza B infection in ferrets with postprandial hyperinsulinemia.
Insulin Resistance
Adipose tissue lipoprotein lipase and hormone-sensitive lipase. Contrasting findings in familial combined hyperlipidemia and insulin resistance syndrome.
Insulin Resistance
Adipose triglyceride lipase and hormone-sensitive lipase protein expression in subcutaneous adipose tissue is decreased after an isoenergetic low-fat high-complex carbohydrate diet in the metabolic syndrome.
Insulin Resistance
Adipose triglyceride lipase and hormone-sensitive lipase protein expression is decreased in the obese insulin-resistant state.
Insulin Resistance
Antiobesity Effect of a Small Molecule Repressor of ROR?.
Insulin Resistance
Atrial natriuretic peptide inhibits the production of adipokines and cytokines linked to inflammation and insulin resistance in human subcutaneous adipose tissue.
Insulin Resistance
Carbazates as potent inhibitors of hormone-sensitive lipase.
Insulin Resistance
FNDC5 overexpression and irisin ameliorate glucose/lipid metabolic derangements and enhance lipolysis in obesity.
Insulin Resistance
High-fat diet-mediated lipotoxicity and insulin resistance is related to impaired lipase expression in mouse skeletal muscle.
Insulin Resistance
Hormone-sensitive lipase knockout mice have increased hepatic insulin sensitivity and are protected from short-term diet-induced insulin resistance in skeletal muscle and heart.
Insulin Resistance
Hormone-sensitive lipase null mice exhibit signs of impaired insulin sensitivity whereas insulin secretion is intact.
Insulin Resistance
Impaired adipocyte lipolysis in nonobese women with the polycystic ovary syndrome: a possible link to insulin resistance?
Insulin Resistance
In vivo modulation of plasma free fatty acids in patients with familial combined hyperlipidemia using lipid-lowering medication.
Insulin Resistance
Interaction between hormone-sensitive lipase and ChREBP in fat cells controls insulin sensitivity.
Insulin Resistance
Male hypogonadism: The unrecognized cardiovascular risk factor.
Insulin Resistance
Omics Analyses Reveal a Potential Link between Hormone-Sensitive Lipase and Polyamine Metabolism.
Insulin Resistance
Peroxisome proliferator-activated receptor-alpha,gamma-agonist improves insulin sensitivity and prevents loss of left ventricular function in obese dyslipidemic mice.
Insulin Resistance
Peroxisome proliferator-activated receptor-gamma transcriptionally up-regulates hormone-sensitive lipase via the involvement of specificity protein-1.
Insulin Resistance
Risk interaction of obesity, insulin resistance and hormone-sensitive lipase promoter polymorphisms (LIPE-60 C > G) in the development of fatty liver.
Insulin Resistance
Specific inhibition of hormone-sensitive lipase improves lipid profile while reducing plasma glucose.
Insulin Resistance
The 1975 type Japanese diet improves the gut microbial flora and inhibits visceral fat accumulation in mice.
Insulin Resistance
The in vivo effects of the Pro12Ala PPARgamma2 polymorphism on adipose tissue NEFA metabolism: the first use of the Oxford Biobank.
Insulin Resistance
Two novel prevalent polymorphisms in the hormone-sensitive lipase gene have no effect on insulin sensitivity of lipolysis and glucose disposal.
Insulin Resistance
[Diagnosis of Secondary Hyperlipidemia due to Diabetes].
Ketosis
Concentrations of Plasma Metabolites, Hormones, and mRNA Abundance of Adipose Leptin and Hormone-Sensitive Lipase in Ketotic and Nonketotic Dairy Cows.
Lipidoses
Metabolic and hormonal alterations in cats with hepatic lipidosis.
Lipodystrophy
Advanced lipodystrophy reverses fatty liver in mice lacking adipocyte hormone-sensitive lipase.
Lipoma
Lipoprotein lipase and hormone-sensitive lipase activities in human subcutaneous lipomas: comparison with normal subcutaneous adipose tissue.
Liver Diseases
n-3 Polyunsaturated fatty acids for the management of alcoholic liver disease: A critical review.
Liver Diseases, Alcoholic
n-3 Polyunsaturated fatty acids for the management of alcoholic liver disease: A critical review.
Lymphoma, B-Cell
Trace Mineral Overload Induced Hepatic Oxidative Damage and Apoptosis in Pigs with Long-Term High-Level Dietary Mineral Exposure.
Marek Disease
vLIP, a viral lipase homologue, is a virulence factor of Marek's disease virus.
Metabolic Syndrome
Adipose triglyceride lipase and hormone-sensitive lipase protein expression in subcutaneous adipose tissue is decreased after an isoenergetic low-fat high-complex carbohydrate diet in the metabolic syndrome.
Metabolic Syndrome
Effect of Glycine on Adipocyte Hypertrophy in a Metabolic Syndrome Rat Model.
Metabolic Syndrome
Genetics of the metabolic syndrome.
Metabolic Syndrome
Synthesis and structure-activity relationship for a novel class of potent and selective carbamoyl-triazole based inhibitors of hormone sensitive lipase.
Muscular Atrophy
The alleviative effects and related mechanisms of taurine supplementation on growth performance and carcass characteristics in broilers exposed to chronic heat stress.
Muscular Diseases
Inborn errors of cytoplasmic triglyceride metabolism.
Neoplasms
1-(3',5'-dihydroxyphenoxy)-7-(2'',4'',6-trihydroxyphenoxy)-2,4,9-trihydroxydibenzo-1,4-dioxin Inhibits Adipocyte Differentiation of 3T3-L1 Fibroblasts.
Neoplasms
A sib-pair analysis study of 15 candidate genes in French families with morbid obesity: indication for linkage with islet 1 locus on chromosome 5q.
Neoplasms
Aberrations in normal systemic lipid metabolism in ovarian cancer patients.
Neoplasms
Activity and tissue-specific expression of lipases and tumor-necrosis factor alpha in lean and obese cats.
Neoplasms
Adipose tissue loss in adjuvant arthritis is associated with a decrease in lipogenesis, but not with an increase in lipolysis.
Neoplasms
An unannotated alpha/beta hydrolase superfamily member, ABHD6 differentially expressed among cancer cell lines.
Neoplasms
Bioactive compounds in plant materials for the prevention of diabetesand obesity.
Neoplasms
Cancer cachexia.
Neoplasms
Cyclooxygenase-2 inhibition reverts the decrease in adiponectin levels and attenuates the loss of white adipose tissue during chronic inflammation.
Neoplasms
Depot-related gene expression in human subcutaneous and omental adipocytes.
Neoplasms
Effect of dermcidin, an antimicrobial peptide, on body fat mobilization in normal mice.
Neoplasms
Exogenous FABP4 interferes with differentiation, promotes lipolysis and inflammation in adipocytes.
Neoplasms
Expression of Lipid Metabolism-Related Proteins Differs between Invasive Lobular Carcinoma and Invasive Ductal Carcinoma.
Neoplasms
Fats and Mets, KRAS-Driven Lipid Dysregulation Affects Metastatic Potential in Pancreatic Cancer.
Neoplasms
High expression of the evolutionarily conserved alpha/beta hydrolase domain containing 6 (ABHD6) in Ewing tumors.
Neoplasms
Increased expression of the mRNA for hormone-sensitive lipase in adipose tissue of cancer patients.
Neoplasms
Lipases and lipid droplet-associated protein expression in subcutaneous white adipose tissue of cachectic patients with cancer.
Neoplasms
Mechanisms to explain wasting of muscle and fat in cancer cachexia.
Neoplasms
n-3 Polyunsaturated fatty acids for the management of alcoholic liver disease: A critical review.
Neoplasms
Normal and pathological human testes express hormone-sensitive lipase and the lipid receptors CLA-1/SR-BI and CD36.
Neoplasms
Obesity and polymorphisms in genes regulating human adipose tissue.
Neoplasms
Obesity--a genetic disease of adipose tissue?
Neoplasms
Phosphorylated glucosamine inhibits adipogenesis in 3T3-L1 adipocytes.
Neoplasms
Regulation of adipocytes lipolysis by n-3 HUFA in grass carp (Ctenopharyngodon idellus) in vitro and in vivo.
Neoplasms
Relative contribution of adipose triglyceride lipase and hormone-sensitive lipase to tumor necrosis factor-? (TNF-?)-induced lipolysis in adipocytes.
Neoplasms
Role of beta1-adrenoceptor in increased lipolysis in cancer cachexia.
Neoplasms
The human breast carcinoma cell line HBL-100 acquires exogenous cholesterol from high-density lipoprotein via CLA-1 (CD-36 and LIMPII analogous 1)-mediated selective cholesteryl ester uptake.
Neoplasms
Tumor necrosis factor increases the rate of lipolysis in primary cultures of adipocytes without altering levels of hormone-sensitive lipase.
Neoplasms
Wheat gluten intake increases weight gain and adiposity associated with reduced thermogenesis and energy expenditure in an animal model of obesity.
Non-alcoholic Fatty Liver Disease
n-3 Polyunsaturated fatty acids for the management of alcoholic liver disease: A critical review.
Obesity
A common hormone-sensitive lipase i6 gene polymorphism is associated with decreased human adipocyte lipolytic function.
Obesity
Absence of hormone-sensitive lipase inhibits obesity and adipogenesis in Lep ob/ob mice.
Obesity
Adipocyte lipolysis in normal weight subjects with obesity among first-degree relatives.
Obesity
Adiponectin expression and adipose tissue lipolytic activity in lean and obese women.
Obesity
Antiobesity Effect of a Small Molecule Repressor of ROR?.
Obesity
Comparative studies of the role of hormone-sensitive lipase and adipose triglyceride lipase in human fat cell lipolysis.
Obesity
Decreased expression and function of adipocyte hormone-sensitive lipase in subcutaneous fat cells of obese subjects.
Obesity
Depot-specific differences in perilipin and hormone-sensitive lipase expression in lean and obese.
Obesity
Effect of diet on fat cell size and hormone-sensitive lipase activity.
Obesity
Effect of Glycine on Adipocyte Hypertrophy in a Metabolic Syndrome Rat Model.
Obesity
Effect of Physical Training on the Adipose Tissue of Diet-induced Obesity Mice: Interaction Between Reactive Oxygen Species and Lipolysis.
Obesity
Effect of pu-erh tea on body fat and lipid profiles in rats with diet-induced obesity.
Obesity
Expression of nitric oxide synthases in subcutaneous adipose tissue of nonobese and obese humans.
Obesity
Fatty acid metabolism and insulin secretion in pancreatic beta cells.
Obesity
Genetic variance and lipolysis regulation: implications for obesity.
Obesity
Hormone-sensitive lipase knockout mice have increased hepatic insulin sensitivity and are protected from short-term diet-induced insulin resistance in skeletal muscle and heart.
Obesity
Hormone-sensitive lipase serine phosphorylation and glycerol exchange across skeletal muscle in lean and obese subjects: effect of beta-adrenergic stimulation.
Obesity
Human hormone-sensitive lipase (HSL): expression in white fat corrects the white adipose phenotype of HSL-deficient mice.
Obesity
Human hormone-sensitive lipase: genetic mapping, identification of a new dinucleotide repeat, and association with obesity and NIDDM.
Obesity
Importance of TNFalpha and neutral lipases in human adipose tissue lipolysis.
Obesity
Inhibitory effects of grape seed extract on lipases.
Obesity
Ishige okamurae Extract Suppresses Obesity and Hepatic Steatosis in High Fat Diet-Induced Obese Mice.
Obesity
Letting lipids go: hormone-sensitive lipase.
Obesity
Millennium fat-cell lipolysis reveals unsuspected novel tracks.
Obesity
Resistance to high-fat diet-induced obesity and altered expression of adipose-specific genes in HSL-deficient mice.
Obesity
Risk interaction of obesity, insulin resistance and hormone-sensitive lipase promoter polymorphisms (LIPE-60 C > G) in the development of fatty liver.
Obesity
Skeletal Muscle Lipase Content and Activity in Obesity and Type 2 Diabetes.
Obesity
Targeted disruption of hormone-sensitive lipase results in male sterility and adipocyte hypertrophy, but not in obesity.
Obesity
The hormone-sensitive lipase (LIPE) gene located on chromosome 19q13.1-->13.2 is not duplicated on 19p13.3.
Obesity
Zinc-alpha2-glycoprotein in cachexia and obesity.
Obesity
[Expression of hormone-sensitive lipase mRNA in diet-induced obesity resistant rats]
Obesity, Abdominal
The putative role of the hormone-sensitive lipase gene in the pathogenesis of Type II diabetes mellitus and abdominal obesity.
Overweight
Blunted beta-adrenoceptor-mediated fat oxidation in overweight subjects: a role for the hormone-sensitive lipase gene.
Pancreatic Neoplasms
Deficiency in hormone-sensitive lipase accelerates the development of pancreatic cancer in conditional KrasG12D mice.
Pancreatic Neoplasms
Fats and Mets, KRAS-Driven Lipid Dysregulation Affects Metastatic Potential in Pancreatic Cancer.
Paralysis
Phenytoin alters transcript levels of hormone-sensitive lipase in muscle from horses with hyperkalemic periodic paralysis.
Paralysis, Hyperkalemic Periodic
Phenytoin alters transcript levels of hormone-sensitive lipase in muscle from horses with hyperkalemic periodic paralysis.
Polycystic Ovary Syndrome
Omental adipose tissue overexpression of fatty acid transporter CD36 and decreased expression of hormone-sensitive lipase in insulin-resistant women with polycystic ovary syndrome.
Pulmonary Emphysema
Age-related pulmonary emphysema in mice lacking alpha/beta hydrolase domain containing 2 gene.
Sarcoma
High expression of the evolutionarily conserved alpha/beta hydrolase domain containing 6 (ABHD6) in Ewing tumors.
Starvation
A Novel Lipase Belonging to the Hormone-sensitive Lipase Family Induced under Starvation to Utilize Stored Triacylglycerol in Mycobacterium tuberculosis.
Starvation
Effect of nutritional status on swine adipose tissue lipolytic activities.
Starvation
Effect of starvation on activities and mRNA expression of lipoprotein lipase and hormone-sensitive lipase in tilapia (Oreochromis niloticus x O. areus).
Starvation
Mechanism of actions of adrenaline and ACTH in fat mobilization.
Tuberculosis
A Novel Lipase Belonging to the Hormone-sensitive Lipase Family Induced under Starvation to Utilize Stored Triacylglycerol in Mycobacterium tuberculosis.
Tuberculosis
MmPPOX inhibits Mycobacterium tuberculosis lipolytic enzymes belonging to the hormone-sensitive lipase family and alters mycobacterial growth.
Tuberculosis
Overexpression of Rv3097c in Mycobacterium bovis BCG abolished the efficacy of BCG vaccine to protect against Mycobacterium tuberculosis infection in mice.
Tuberculosis
Substrate specificity and kinetic properties of enzymes belonging to the hormone-sensitive lipase family: comparison with non-lipolytic and lipolytic carboxylesterases.
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Yeaman, S.J.
Hormone-sensitive lipase - new roles for an old enzyme
Biochem. J.
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11-22
2004
Homo sapiens, Mus musculus, Rattus norvegicus
brenda
Remaury, A.; Laurell, H.; Grober, J.; Reynisdottir, S.; Dauzats, M.; Holm, C.; Langin, D.
Expression of hormone-sensitive lipase in the human colon adenocarcinoma cell line HT29
Biochem. Biophys. Res. Commun.
207
175-182
1995
Homo sapiens
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Mairal, A.; Melaine, N.; Laurell, H.; Grober, J.; Holst, L.S.; Guillaudeux, T.; Holm, C.; Jegou, B.; Langin, D.
Characterization of a novel testicular form of human hormone-sensitive lipase
Biochem. Biophys. Res. Commun.
291
286-290
2002
Homo sapiens
brenda
Ben Ali, Y.; Chahinian, H.; Petry, S.; Muller, G.; Carriere, F.; Verger, R.; Abousalham, A.
Might the kinetic behavior of hormone-sensitive lipase reflect the absence of the lid domain?
Biochemistry
43
9298-9306
2004
Homo sapiens
brenda
Holm, C.; Belfrage, P.; Fredrikson, G.
Human adipose tissue hormone-sensitive lipase: identification and comparison with other species
Biochim. Biophys. Acta
1006
193-197
1989
Homo sapiens, Rattus norvegicus
brenda
Osterlund, T.
Structure-function relationships of hormone-sensitive lipase
Eur. J. Biochem.
268
1899-1907
2001
Homo sapiens, Mus musculus, Rattus norvegicus
brenda
Raclot, T.; Holm, C.; Langin, D.
Fatty acid specificity of hormone-sensitive lipase: implication in the selective hydrolysis of triacylglycerols
J. Lipid Res.
42
2049-2057
2001
Homo sapiens, Rattus norvegicus
brenda
Chahinian, H.; Ali, Y.B.; Abousalham, A.; Petry, S.; Mandrich, L.; Manco, G.; Canaan, S.; Sarda, L.
Substrate specificity and kinetic properties of enzymes belonging to the hormone-sensitive lipase family: comparison with non-lipolytic and lipolytic carboxylesterases
Biochim. Biophys. Acta
1738
29-36
2005
Homo sapiens
brenda
De Jong, J.C.; Sorensen, L.G.; Tornqvist, H.; Jacobsen, P.
Carbazates as potent inhibitors of hormone-sensitive lipase
Bioorg. Med. Chem. Lett.
14
1741-1744
2004
Homo sapiens
brenda
O'Neill, M.; Watt, M.J.; Heigenhauser, G.J.; Spriet, L.L.
Effects of reduced free fatty acid availability on hormone-sensitive lipase activity in human skeletal muscle during aerobic exercise
J. Appl. Physiol.
97
1938-1945
2004
Homo sapiens
brenda
Ben Ali, Y.; Carriere, F.; Verger, R.; Petry, S.; Muller, G.; Abousalham, A.
Continuous monitoring of cholesterol oleate hydrolysis by hormone-sensitive lipase and other cholesterol esterases
J. Lipid Res.
46
994-1000
2005
Homo sapiens
brenda
Claus, T.H.; Lowe, D.B.; Liang, Y.; Salhanick, A.I.; Lubeski, C.K.; Yang, L.; Lemoine, L.; Zhu, J.; Clairmont, K.B.
Specific inhibition of hormone-sensitive lipase improves lipid profile while reducing plasma glucose
J. Pharmacol. Exp. Ther.
315
1396-1402
2005
Homo sapiens
brenda
Roepstorff, C.; Vistisen, B.; Donsmark, M.; Nielsen, J.N.; Galbo, H.; Green, K.A.; Hardie, D.G.; Wojtaszewski, J.F.; Richter, E.A.; Kiens, B.
Regulation of hormone-sensitive lipase activity and Ser563 and Ser565 phosphorylation in human skeletal muscle during exercise
J. Physiol.
560
551-562
2004
Homo sapiens
brenda
Watt, M.J.; Spriet, L.L.
Regulation and role of hormone-sensitive lipase activity in human skeletal muscle
Proc. Nutr. Soc.
63
315-322
2004
Homo sapiens
brenda
Roepstorff, C.; Donsmark, M.; Thiele, M.; Vistisen, B.; Stewart, G.; Vissing, K.; Schjerling, P.; Hardie, D.G.; Galbo, H.; Kiens, B.
Sex differences in hormone-sensitive lipase expression, activity, and phosphorylation in skeletal muscle at rest and during exercise
Am. J. Physiol. Endocrinol. Metab.
291
E1106-E1114
2006
Homo sapiens
brenda
Ryden, M.; Jocken, J.; van Harmelen, V.; Dicker, A.; Hoffstedt, J.; Wiren, M.; Blomqvist, L.; Mairal, A.; Langin, D.; Blaak, E.; Arner, P.
Comparative studies of the role of hormone-sensitive lipase and adipose triglyceride lipase in human fat cell lipolysis
Am. J. Physiol. Endocrinol. Metab.
292
E1847-E1855
2007
Homo sapiens (Q05469), Homo sapiens
brenda
Aboulaich, N.; Ortegren, U.; Vener, A.V.; Stralfors, P.
Association and insulin regulated translocation of hormone-sensitive lipase with PTRF
Biochem. Biophys. Res. Commun.
350
657-661
2006
Homo sapiens
brenda
Palin, S.L.; McTernan, P.G.; McGee, K.C.; Sturdee, D.W.; Barnett, A.H.; Kumar, S.
Dydrogesterone and norethisterone regulate expression of lipoprotein lipase and hormone-sensitive lipase in human subcutaneous abdominal adipocytes
Diabetes Obes. Metab.
9
585-590
2007
Homo sapiens
brenda
Helge, J.W.; Biba, T.O.; Galbo, H.; Gaster, M.; Donsmark, M.
Muscle triacylglycerol and hormone-sensitive lipase activity in untrained and trained human muscles
Eur. J. Appl. Physiol.
97
566-572
2006
Homo sapiens
brenda
Smith, A.J.; Thompson, B.R.; Sanders, M.A.; Bernlohr, D.A.
Interaction of the adipocyte fatty acid-binding protein with the hormone-sensitive lipase: regulation by fatty acids and phosphorylation
J. Biol. Chem.
282
32424-32432
2007
Homo sapiens
brenda
Fernandez, C.; Hansson, O.; Nevsten, P.; Holm, C.; Klint, C.
Hormone-sensitive lipase is necessary for normal mobilization of lipids during submaximal exercise
Am. J. Physiol. Endocrinol. Metab.
295
E179-E186
2008
Homo sapiens (Q05469)
brenda
Jocken, J.W.; Roepstorff, C.; Goossens, G.H.; van der Baan, P.; van Baak, M.; Saris, W.H.; Kiens, B.; Blaak, E.E.
Hormone-sensitive lipase serine phosphorylation and glycerol exchange across skeletal muscle in lean and obese subjects: effect of beta-adrenergic stimulation
Diabetes
57
1834-1841
2008
Homo sapiens
brenda
Krintel, C.; Osmark, P.; Larsen, M.R.; Resjoe, S.; Logan, D.T.; Holm, C.
Ser649 and Ser650 are the major determinants of protein kinase A-mediated activation of human hormone-sensitive lipase against lipid substrates
PLoS ONE
3
e3756
2008
Homo sapiens (Q05469), Homo sapiens
brenda
Minkkilä, A.; Savinainen, J.; Käsnänen, H.; Xhaard, H.; Nevalainen, T.; Laitinen, J.; Poso, A.; Leppänen, J.; Saario, S.
Screening of various hormone-sensitive lipase inhibitors as endocannabinoid-hydrolyzing enzyme inhibitors
ChemMedChem
4
1253-1259
2009
Homo sapiens
brenda
Rodriguez, J.; Ben Ali, Y.; Abdelkafi, S.; Mendoza, L.; Leclaire, J.; Fotiadu, F.; Buono, G.; Carrière, F.; Abousalham, A.
In vitro stereoselective hydrolysis of diacylglycerols by hormone-sensitive lipase
Biochim. Biophys. Acta
1801
77-83
2010
Homo sapiens
brenda
Tanigawa, K.; Degang, Y.; Kawashima, A.; Akama, T.; Yoshihara, A.; Ishido, Y.; Makino, M.; Ishii, N.; Suzuki, K.
Essential role of hormone-sensitive lipase (HSL) in the maintenance of lipid storage in Mycobacterium leprae-infected macrophages
Microb. Pathog.
52
285-291
2012
Homo sapiens
brenda
Ogiyama, T.; Yamaguchi, M.; Kurikawa, N.; Honzumi, S.; Yamamoto, Y.; Sugiyama, D.; Takakusa, H.; Inoue, S.I.
Identification of a novel hormone sensitive lipase inhibitor with a reduced potential of reactive metabolites formation
Bioorg. Med. Chem.
25
2234-2243
2017
Homo sapiens
brenda
Ogiyama, T.; Yamaguchi, M.; Kurikawa, N.; Honzumi, S.; Terayama, K.; Nagaoka, N.; Yamamoto, Y.; Kimura, T.; Sugiyama, D.; Inoue, S.I.
Design, synthesis, and pharmacological evaluation of a novel series of hormone sensitive lipase inhibitor
Bioorg. Med. Chem.
25
4817-4828
2017
Homo sapiens
brenda
Whytock, K.L.; Shepherd, S.O.; Wagenmakers, A.J.M.; Strauss, J.A.
Hormone-sensitive lipase preferentially redistributes to lipid droplets associated with perilipin-5 in human skeletal muscle during moderate-intensity exercise
J. Physiol.
596
2077-2090
2018
Homo sapiens (Q05469), Homo sapiens
brenda