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Disease on EC 3.1.1.53 - sialate O-acetylesterase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Addison Disease
The role of functionally defective rare germline variants of sialic acid acetylesterase in autoimmune Addison's disease.
Anemia
A hemagglutinin-esterase-expressing salmonid alphavirus replicon protects Atlantic salmon (Salmo salar) against infectious salmon anemia (ISA).
Adjuvant activity of fish type I interferon shown in a virus DNA vaccination model.
Anguillid herpesvirus 1 (AngHV) ORF95 encodes a late, structural envelope protein.
Heterologous expression and purification of the infectious salmon anemia virus hemagglutinin esterase.
IFN-adjuvanted DNA vaccine against infectious salmon anemia virus: Antibody kinetics and longevity of IFN expression.
Protective effects of a DNA vaccine expressing the infectious salmon anemia virus hemagglutinin-esterase in Atlantic salmon.
Salmonid alphavirus-based replicon vaccine against infectious salmon anemia (ISA): impact of immunization route and interactions of the replicon vector.
Structural and functional analysis of the hemagglutinin-esterase of infectious salmon anaemia virus.
Arthritis, Rheumatoid
Lack of association between rare mutations of the SIAE gene and rheumatoid arthritis in a Han Chinese population.
Autoimmune Diseases
A missense single-nucleotide polymorphism in the sialic acid acetylesterase (SIAE) gene is associated with anti-PIT-1 antibody syndrome.
Functionally defective germline variant of sialic acid acetylesterase (Met89Val) is not associated with type 1 diabetes mellitus and Graves' disease in a Polish population.
Lack of association between rare mutations of the SIAE gene and rheumatoid arthritis in a Han Chinese population.
Transcriptional profiling of human placentas from pregnancies complicated by preeclampsia reveals disregulation of sialic acid acetylesterase and immune signalling pathways.
Autoimmune Hypophysitis
A missense single-nucleotide polymorphism in the sialic acid acetylesterase (SIAE) gene is associated with anti-PIT-1 antibody syndrome.
Colitis, Ulcerative
The roles of enteric bacterial sialidase, sialate O-acetyl esterase and glycosulfatase in the degradation of human colonic mucin.
COVID-19
Hemagglutinin-esterase cannot be considered as a candidate for designing drug against COVID-19.
How do arbidol and its analogs inhibit the SARS-CoV-2?
Phylogenic analysis of coronavirus genome and molecular studies on potential anti-COVID-19 agents from selected FDA-approved drugs.
Role of Glycoprotein Hemagglutinin-Esterase in COVID-19 Pathophysiology?
Role of hemagglutinin esterase protein in neurological manifestation of COVID-19.
Demyelinating Diseases
The detection and characterization of multiple hemagglutinin-esterase (HE)-defective viruses in the mouse brain during subacute demyelination induced by mouse hepatitis virus.
Diabetes Mellitus
Functionally defective germline variant of sialic acid acetylesterase (Met89Val) is not associated with type 1 diabetes mellitus and Graves' disease in a Polish population.
Diabetes Mellitus, Type 1
A missense single-nucleotide polymorphism in the sialic acid acetylesterase (SIAE) gene is associated with anti-PIT-1 antibody syndrome.
Functionally defective germline variant of sialic acid acetylesterase (Met89Val) is not associated with type 1 diabetes mellitus and Graves' disease in a Polish population.
Dysentery
A multigene approach for comparing genealogy of Betacoronavirus from cattle and horses.
Characterization of monoclonal antibodies to the hemagglutinin-esterase glycoprotein of a bovine coronavirus associated with winter dysentery and cross-reactivity to field isolates.
Genomic and antigenic variations of the HE glycoprotein of bovine coronaviruses associated with neonatal calf diarrhea and winter dysentery.
Encephalitis
The detection and characterization of multiple hemagglutinin-esterase (HE)-defective viruses in the mouse brain during subacute demyelination induced by mouse hepatitis virus.
Glioma
Targeting the GD3 acetylation pathway selectively induces apoptosis in glioblastoma.
Graves Disease
Functionally defective germline variant of sialic acid acetylesterase (Met89Val) is not associated with type 1 diabetes mellitus and Graves' disease in a Polish population.
Hepatitis
Attachment of mouse hepatitis virus to O-acetylated sialic acid is mediated by hemagglutinin-esterase and not by the spike protein.
Coronavirus defective-interfering RNA as an expression vector: the generation of a pseudorecombinant mouse hepatitis virus expressing hemagglutinin-esterase.
Expression of hemagglutinin esterase protein from recombinant mouse hepatitis virus enhances neurovirulence.
Hemagglutinin-esterase-specific monoclonal antibodies alter the neuropathogenicity of mouse hepatitis virus.
Heterogeneity of gene expression of the hemagglutinin-esterase (HE) protein of murine coronaviruses.
Identification of a coronavirus hemagglutinin-esterase with a substrate specificity different from those of influenza C virus and bovine coronavirus.
Interaction of mouse hepatitis virus (MHV) spike glycoprotein with receptor glycoprotein MHVR is required for infection with an MHV strain that expresses the hemagglutinin-esterase glycoprotein.
Localisation and distribution of O-acetylated N-acetylneuraminic acids, the endogenous substrates of the hemagglutinin-esterases of murine coronaviruses, in mouse tissue.
Luxury at a cost? Recombinant mouse hepatitis viruses expressing the accessory hemagglutinin esterase protein display reduced fitness in vitro.
Neuropathogenicity of mouse hepatitis virus JHM isolates differing in hemagglutinin-esterase protein expression.
Synthesis and inhibitory activity of sialic acid derivatives targeted at viral sialate-O-acetylesterases.
The detection and characterization of multiple hemagglutinin-esterase (HE)-defective viruses in the mouse brain during subacute demyelination induced by mouse hepatitis virus.
The hemagglutinin-esterase of mouse hepatitis virus strain S is a sialate-4-O-acetylesterase.
Infections
A DNA vaccine expressing consensus hemagglutinin-esterase fusion protein protected guinea pigs from infection by two lineages of influenza D virus.
An emerging novel bovine coronavirus with a 4-amino-acid insertion in the receptor-binding domain of the hemagglutinin-esterase gene.
Human Coronavirus HKU1 Spike Protein Uses O-Acetylated Sialic Acid as an Attachment Receptor Determinant and Employs Hemagglutinin-Esterase Protein as a Receptor-Destroying Enzyme.
Interaction of mouse hepatitis virus (MHV) spike glycoprotein with receptor glycoprotein MHVR is required for infection with an MHV strain that expresses the hemagglutinin-esterase glycoprotein.
[Influenza C virus isolated in Hiroshima Prefecture during the 1999/2000 winter season--a clinical and epidemiological study]
Inflammatory Bowel Diseases
Degradation by bacterial enzymes of colonic mucus from normal subjects and patients with inflammatory bowel disease: the role of sialic acid metabolism and the detection of a novel O-acetylsialic acid esterase.
Influenza, Human
9-O-acetylated sialic acids have widespread but selective expression: analysis using a chimeric dual-function probe derived from influenza C hemagglutinin-esterase.
9-O-Acetylation of sialomucins: a novel marker of murine CD4 T cells that is regulated during maturation and activation.
A DNA vaccine expressing consensus hemagglutinin-esterase fusion protein protected guinea pigs from infection by two lineages of influenza D virus.
A mouse monoclonal antibody against influenza C virus attenuates acetaminophen-induced liver injury in mice.
Activity of influenza C virus O-acetylesterase with O-acetyl-containing compounds.
Alterations in sialic-acid O-acetylation glycoforms during murine erythrocyte development.
Analyses of Evolutionary Characteristics of the Hemagglutinin-Esterase Gene of Influenza C Virus during a Period of 68 Years Reveals Evolutionary Patterns Different from Influenza A and B Viruses.
Antigenic and genetic characterization of influenza C viruses which caused two outbreaks in Yamagata City, Japan, in 1996 and 1998.
Antigenic changes among the predominantly circulating C/Sao Paulo lineage strains of influenza C virus in Yamagata, Japan, between 2015 and 2018.
Cell surface expression of biologically active influenza C virus HEF glycoprotein expressed from cDNA.
Comparison of the genome organization of toro- and coronaviruses: evidence for two nonhomologous RNA recombination events during Berne virus evolution.
Crystal structure of unliganded influenza B virus hemagglutinin.
Developmentally expressed O-acetyl ganglioside GT3 in fetal rat cerebral cortex.
Domain-structure of cytoplasmic border region is main determinant for palmitoylation of influenza virus hemagglutinin (H7).
Evolutionary analysis of influenza C virus M genes.
Evolutionary changes of the novel Influenza D virus hemagglutinin-esterase fusion gene revealed by the codon usage pattern.
Expression, antigenicity and studies on cell receptor binding of the hemagglutinin of infectious salmon anemia virus.
Frequent reassortment among influenza C viruses.
Growth Kinetics of Influenza C Virus Antigenic Mutants That Escaped from Anti-Hemagglutinin Esterase Monoclonal Antibodies and Viral Antigenic Changes Found in Field Isolates.
Hemagglutinating encephalomyelitis virus attaches to N-acetyl-9-O-acetylneuraminic acid-containing receptors on erythrocytes: comparison with bovine coronavirus and influenza C virus.
Identification of a coronavirus hemagglutinin-esterase with a substrate specificity different from those of influenza C virus and bovine coronavirus.
Increased influenza A virus sialidase activity with N-acetyl-9-O-acetylneuraminic acid-containing substrates resulting from influenza C virus O-acetylesterase action.
Influenza C virus and bovine coronavirus esterase reveal a similar catalytic mechanism: new insights for drug discovery.
Influenza C virus esterase: analysis of catalytic site, inhibition, and possible function.
Isolation and characterization of influenza C viruses in the Philippines and Japan.
Isolation and characterization of sialate 9(4)-O-acetylesterase from influenza C virus.
Location of a linear epitope recognized by monoclonal antibody S16 on the hemagglutinin-esterase glycoprotein of influenza C virus.
Location of neutralizing epitopes on the hemagglutinin-esterase protein of influenza C virus.
Longitudinal course of influenza C virus antibody titers of healthy adults in Sendai, Japan.
Neutralizing Epitopes and Residues Mediating the Potential Antigenic Drift of the Hemagglutinin-Esterase Protein of Influenza C Virus.
Origin and evolution of influenza virus hemagglutinin genes.
Recombinant influenza C hemagglutinin-esterase as a probe for sialic acid 9-O-acetylation.
Recombinant viral sialate-O-acetylesterases.
Role of individual oligosaccharide chains in antigenic properties, intracellular transport, and biological activities of influenza C virus hemagglutinin-esterase protein.
Selection of antigenically distinct variants of influenza C viruses by the host cell.
Sialate O-acetylesterases: key enzymes in sialic acid catabolism.
Structural and functional analysis of the hemagglutinin-esterase of infectious salmon anaemia virus.
Structural basis for human coronavirus attachment to sialic acid receptors.
Structure of coronavirus hemagglutinin-esterase offers insight into corona and influenza virus evolution.
Study of influenza C virus infection in France.
Study of the O-acetylesterase activity of five influenza C virus strains.
Synthesis and inhibitory activity of sialic acid derivatives targeted at viral sialate-O-acetylesterases.
Synthesis and inhibitory properties of a thiomethylmercuric sialic acid with application to the X-ray structure determination of 9-O-acetylsialic acid esterase from influenza C virus.
The catalytic triad of the influenza C virus glycoprotein HEF esterase: characterization by site-directed mutagenesis and functional analysis.
The glycoprotein of influenza C virus is the haemagglutinin, esterase and fusion factor.
The Hemagglutinin-Esterase Fusion Glycoprotein Is a Primary Determinant of the Exceptional Thermal and Acid Stability of Influenza D Virus.
The hemagglutinin-esterase of mouse hepatitis virus strain S is a sialate-4-O-acetylesterase.
The receptor-destroying enzyme of influenza C virus is required for entry into target cells.
Tissue Microarrays to Visualize Influenza D Attachment to Host Receptors in the Respiratory Tract of Farm Animals.
TMPRSS2 activates hemagglutinin-esterase glycoprotein of influenza C virus.
Use of influenza C virus for detection of 9-O-acetylated sialic acids on immobilized glycoconjugates by esterase activity.
YesT: a new rhamnogalacturonan acetyl esterase from Bacillus subtilis.
[Evolutionary analysis of the hemagglutinin-esterase (HE) gene of influenza C virus]
[Studies on sialidase and esterase in influenza viruses]
[The nature of the influenza C virus receptor and the specificity of the receptor-destroying enzyme]
[The structure and function of the HE protein of influenza C virus]
[Type C influenza]
Liver Cirrhosis, Biliary
Association of primary biliary cirrhosis with variants in the CLEC16A, SOCS1, SPIB and SIAE immunomodulatory genes.
Melanoma
Selection of antigenically distinct variants of influenza C viruses by the host cell.
Neurologic Manifestations
Response to the letter, entitled "Role of hemagglutinin esterase protein in neurological manifestation of COVID-19".
Role of hemagglutinin esterase protein in neurological manifestation of COVID-19.
Pre-Eclampsia
Transcriptional profiling of human placentas from pregnancies complicated by preeclampsia reveals disregulation of sialic acid acetylesterase and immune signalling pathways.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Regulation of O-acetylation of sialic acids by sialate-O-acetyltransferase and sialate-O-acetylesterase activities in childhood acute lymphoblastic leukemia.
Scabies
YesT: a new rhamnogalacturonan acetyl esterase from Bacillus subtilis.
Vaccinia
Characterization of mouse hepatitis virus-specific cytotoxic T cells derived from the central nervous system of mice infected with the JHM strain.
Induction of apoptosis in murine coronavirus-infected cultured cells and demonstration of E protein as an apoptosis inducer.
The hemagglutinin-esterase of mouse hepatitis virus strain S is a sialate-4-O-acetylesterase.