Information on EC 3.1.1.5 - lysophospholipase

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The expected taxonomic range for this enzyme is: Eukaryota, Bacteria, Archaea

EC NUMBER
COMMENTARY hide
3.1.1.5
-
RECOMMENDED NAME
GeneOntology No.
lysophospholipase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2-lysophosphatidylcholine + H2O = glycerophosphocholine + a carboxylate
show the reaction diagram
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
hydrolysis of carboxylic ester
PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
phospholipid remodeling (phosphatidylethanolamine, yeast)
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degradation of sugar alcohols
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Glycerophospholipid metabolism
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SYSTEMATIC NAME
IUBMB Comments
2-lysophosphatidylcholine acylhydrolase
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CAS REGISTRY NUMBER
COMMENTARY hide
9001-85-8
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
Cryptococcus gattii
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Manually annotated by BRENDA team
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
quail
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Automatic Mining of ENzyme DAta
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1065716 A+, 133928 A+, 1426051 A+, 1428408 A+, 1429156 A+, 1429250 A+, 1433719 A+, 1451837 A+, 1451841 A+, 1451888 A+, 1451967 A+, 1451970 A+, 1451999 A+, 1452004 A+, 1452008 A+, 1452011 A+, 1452021 A+, 1452023 A+, 1452028 A+, 1452043 A+, 1452053 A+, 1452085 A+, 1452110 A+, 1452153 A+, 1452165 A+, 1452228 A+, 1452256 A+, 1452290 A+, 1452293 A+, 2156646 A+, 2156849 A+, 2156880 A+, 2165677 A+, 2165679 A+, 2165695 A+, 2165724 A+, 2165732 A+, 2183747 A+, 2186106 A+, 2186792 A+, 2513536 A+, 2552830 A+, 2577842 A+, 2577929 A+, 2577977 A+, 2577981 A+, 2578011 A+, 2578020 A+, 2578021 A+, 2578051 A+, 2578071 A+, 2578081 A+, 2578082 A+, 2578097 A+, 2578104 A+, 2578133 A+, 2578134 A+, 795003 A+, 817367 A+, 834922 A+, 835755 A+, 835838 A+, 835965 A+, 836153 A+, 848671 A+, 848695 A+, 848743 A+, 848744 A+, 848748 A+, 848756 A+, 848760 A+, 848765 A+, 848769 A+, 848787 A+, 848792 A+, 848798 A+, 848802 A+, 848817 A+, 848819 A+, 848846 A+, 848871 A+, 848872 A+, 848886 A+, 848912 A+, 848923 A+, 848925 A+, 848930 A+, 848931 A+, 848934 A+, 848937 A+, 848939 A+, 848943 A+, 848945 A+, 848950 A+, 848958 A+, 848959 A+, 848964 A+, 848968 A+, 848970 A+, 848976 A+, 848977 A+, 848979 A+, 848992 A+, 849006 A+, 849007 A+, 849010 A+, 849012 A+, 849019 A+, 849026 A+, 849030 A+, 849032 A+, 849046 A+, 849052 A+, 849058 A+, 849060 A+, 849081 A+, 849106 A+, 849116 A+, 849148 A+, 849210 A+, 849252 A+, 849265 A+, 849293 A+, 849307 A+, 886536 A+, 887138 A+, 887246 A+, 887443 A+, 887496 A+, 888766 A+, 94312 A+, 94340 A+, 1428674 A++, 1428911 A++, 1429075 A++, 1429243 A++, 1429411 A++, 1429710 A++, 1451845 A++, 1451872 A++, 1452177 A++, 2165680 A++, 2165710 A++, 2165725 A++, 2165763 A++, 2578115 A++, 714838 A++, 848714 A++, 849079 A++, 849131 A++, 849280 A++, 887595 A++, 887911 A++, 94393 A++, 1428965 A++, 1429366 A++, 1452091 A++, 1452144 A++, 1452162 A++, 2157069 A++, 2159180 A++, 2165693 A++, 2165701 A++, 2165723 A++, 2165746 A++, 2577953 A++, 2577968 A++, 650321 A++, 835189 A++, 835212 A++, 836520 A++, 848673 A++, 848779 A++, 848781 A++, 848782 A++, 848868 A++, 848877 A++, 848890 A++, 848891 A++, 848906 A++, 849109 A++, 849211 A++, 928755 A++, 94308 A++, 94392 A++, 94397 A++, 94399 A++, 663851 A+++, 834920 A+++, 835047 A+++, 848750 A+++, 848764 A+++, 848799 A+++, 848873 A+++, 848883 A+++, 848898 A+++, 848904 A+++, 849061 A+++, 849094 A+++, 849101 A+++, 849126 A+++, 849135 A+++, 849182 A+++, 849288 A+++, 849310 A+++, 94307 A+++, 170658 A++++, 649469 A++++, 835291 A++++, 848876 A++++, 848880 A++++, 848889 A++++, 848896 A++++, 848899 A++++, 849097 A++++, 849113 A++++, 849123 A++++, 849142 A++++, 849180 A++++, 849183 A++++, 849195 A++++, 849209 A++++, 849275 A++++, 94387 A++++, 94389 A++++, 94396 A++++
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
toad
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Manually annotated by BRENDA team
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
yeasts
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
malfunction
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lysoPL2 knockout mutants show enhanced sensitivity to Zn2+ and H2O2 in comparison to wild type
metabolism
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the enzyme exerts important functions in the homeostasis of phospholipids or detoxification of lysophospholipids
physiological function
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
1,2,3-trioleoyl-sn-glycerol + H2O
?
show the reaction diagram
1,2-didecanoylphosphatidylcholine + H2O
?
show the reaction diagram
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?
1,2-didodecanoyl-sn-glycero-3-phosphocholine + H2O
?
show the reaction diagram
-
-
-
?
1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O
?
show the reaction diagram
1,2-dioleoylglycerol + H2O
?
show the reaction diagram
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?
1,2-dioleoylphosphatidylcholine + H2O
monooleoyl-lysophosphatidylcholine + oleic acid
show the reaction diagram
-
129% of activity with 1,2-dipalmitoylphosphatidylcholine
-
?
1,2-dioleoylphosphatidylethanolamine + H2O
monooleoyl-lysophosphatidylethanolamine + oleic acid
show the reaction diagram
-
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33.5% of activity with 1,2-dipalmitoylphosphatidylcholine
?
1,2-dioleoylphosphatidylserine + H2O
monooleoyl-lysophosphatidylserine + oleic acid
show the reaction diagram
-
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22.5% of activity with 1,2-dipalmitoylphosphatidylcholine
?
1,2-dipalmitoyl-sn-glycero-3-phosphocholine + H2O
1-palmitoyl-sn-glycero-3-phosphocholine + palmitate
show the reaction diagram
-
-
-
?
1,2-dipalmitoyl-sn-glycero-3-phosphocholine + H2O
?
show the reaction diagram
1,2-dipalmitoylphosphatidylcholine + H2O
?
show the reaction diagram
1,2-palmitylphosphatidylcholine + H2O
1-palmityl-lysophosphatidylcholine + palmitic acid
show the reaction diagram
-
low activity after activating of ExoU with an unknown eukaryotic cell factor
-
?
1-acyl-2-lysophosphatidycholine + H2O
fatty acid + glycerophosphocholine
show the reaction diagram
-
-
-
?
1-acyl-glycerophosphoglycerol + H2O
fatty acid + glcyerophosphoglycerol
show the reaction diagram
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-
-
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?
1-acyl-lysophosphatidylcholine + 1-alkyllysophosphatidylcholine
1-alkyl-2-acyl-phosphatidylcholine + glycerylphosphocholine
show the reaction diagram
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?
1-acyl-sn-glycero-3-phosphate + H2O
fatty acid + glyceryl phosphate
show the reaction diagram
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-
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?
1-acyl-sn-glycero-3-phospho-myo-inositol
fatty acid + glycero-3-phospho-myo-inositol
show the reaction diagram
1-acyl-sn-glycero-3-phosphocholine + H2O
fatty acid + glycero-3-phosphocholine
show the reaction diagram
1-acyl-sn-glycero-3-phosphoserine + H2O
fatty acid + glycerophosphoserine
show the reaction diagram
1-acylglycerophosphoethanolamine + H2O
fatty acid + glycerylphosphoethanolamine
show the reaction diagram
1-arachidonoyl-2-lysophosphatidylcholine + H2O
?
show the reaction diagram
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-
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?
1-docosahexaenoyl-2-lysophosphatidylcholine + H2O
?
show the reaction diagram
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?
1-dodecanoyl-sn-glycero-3-phosphocholine + H2O
?
show the reaction diagram
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?
1-hexanoyl-2-lysophosphatidylcholine + H2O
?
show the reaction diagram
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?
1-hexanoyl-2-lysophosphatidylcholine + H2O
glycerophosphocholine + hexanoate
show the reaction diagram
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?
1-hexyl-glycerophosphocholine + H2O
hexanoate + glycerophosphocholine
show the reaction diagram
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?
1-lauroyl lysophosphatidylcholine + H2O
?
show the reaction diagram
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?
1-lauroyl-2-lysophosphatidylcholine + H2O
?
show the reaction diagram
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?
1-lauroyl-sn-glycero-3-phosphocholine + H2O
lauric acid + sn-glycero-3-phosphocholine
show the reaction diagram
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?
1-lauryl-glycerophosphocholine + H2O
laurate + glycerophosphocholine
show the reaction diagram
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?
1-linoleoyl-2-lysophosphatidylcholine + H2O
?
show the reaction diagram
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?
1-linoleoyl-sn-glycero-3-phosphocholine + H2O
linoleic acid + glycerophosphorylcholine
show the reaction diagram
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?
1-monopalmitoylglycerol + H2O
glycerol + palmitic acid
show the reaction diagram
-
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lipase activity of LPLA
?
1-monopalmitoyllysophosphatidylglycerol + H2O
glycerophosphoglycerol + palmitic acid
show the reaction diagram
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?
1-myristoyl-2-lysophosphatidylcholine + H2O
?
show the reaction diagram
-
-
-
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?
1-myristoyl-sn-glycero-3-phosphocholine + H2O
myristic acid + sn-glycero-3-phosphocholine
show the reaction diagram
-
-
-
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?
1-octanoyl-sn-glycero-3-phosphocholine + H2O
octanoic acid + sn-glycero-3-phosphocholine
show the reaction diagram
-
-
-
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?
1-oleoyl lysophosphatidylcholine + H2O
?
show the reaction diagram
-
-
-
-
?
1-oleoyl lysophosphatidylcholine + H2O
glycerophosphocholine + oleate
show the reaction diagram
Cryptococcus gattii
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30% of the activity with 1-palmitoyl lysophosphatidylcholine, LPL1
-
-
?
1-oleoyl-2-acetyl-sn-glycero-3-phosphocholine + H2O
?
show the reaction diagram
-
-
-
-
?
1-oleoyl-2-lysophosphatidylcholine + H2O
?
show the reaction diagram
-
-
-
-
?
1-oleoyl-2-lysophosphatidylcholine + H2O
glycerophosphocholine + oleate
show the reaction diagram
-
-
-
-
?
1-oleoyl-2-lysophosphatidylcholine + H2O
glycerophosphorylcholine + oleic acid
show the reaction diagram
Cryptococcus gattii
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30% of the activity with 1-palmitoyl lysophosphatidylcholine at pH 5.0, 667% of the activity with 1-palmitoyl lysophosphatidylcholine at pH 7.0
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-
?
1-oleoyl-glycerophosphocholine + H2O
oleate + glycerophosphocholine
show the reaction diagram
-
-
-
-
?
1-oleoyl-lysophosphatidylcholine + H2O
glycerophosphorylcholine + oleic acid
show the reaction diagram
-
194% of activity with 1-palmitoyl-lysophosphatidylcholine
-
?
1-oleoyl-sn-glycero-3-phosphocholine + H2O
oleic acid + glycerophosphorylcholine
show the reaction diagram
1-oleoyl-sn-glycero-3-phosphoethanolamine + H2O
oleic acid + glycero-3-phosphoethanolamine
show the reaction diagram
1-palmitoyl lysophosphatidylcholine + H2O
?
show the reaction diagram
-
-
-
-
?
1-palmitoyl lysophosphatidylcholine + H2O
glycerophosphocholine + palmitate
show the reaction diagram
1-palmitoyl lysophosphatidylcholine + H2O
glycerophosphocholine + palmitic acid
show the reaction diagram
Cryptococcus gattii
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-
-
-
?
1-palmitoyl-2-acetyl-sn-glycero-3-phosphocholine + H2O
?
show the reaction diagram
1-palmitoyl-2-lyso-sn-phosphatidylcholine + H2O
glycerophosphocholine + palmitic acid
show the reaction diagram
-
-
-
?
1-palmitoyl-2-lysophosphatidylcholine + H2O
?
show the reaction diagram
1-palmitoyl-2-lysophosphatidylcholine + H2O
glycerophosphocholine + palmitate
show the reaction diagram
-
-
-
-
?
1-palmitoyl-2-lysophosphatidylcholine + H2O
glycerophosphocholine + palmitic acid
show the reaction diagram
1-palmitoyl-2-lysophosphatidylcholine + H2O
palmitate + glycerophosphocholine
show the reaction diagram
-
-
-
-
?
1-palmitoyl-2-oleoylphosphatidylcholine + H2O
lysophosphatidylcholine + ?
show the reaction diagram
-
36% of activity with 1,2-dipalmitoylphosphatidylcholine
-
?
1-palmitoyl-glycerophosphocholine + H2O
palmitate + glycerophosphocholine
show the reaction diagram
-
-
-
-
?
1-palmitoyl-lysophosphatidylcholine + H2O
glycerophosphocholine + palmitic acid
show the reaction diagram
1-palmitoyl-lysophosphatidylethanolamine + H2O
glycerophosphatidylethanolamine + palmitic acid
show the reaction diagram
1-palmitoyl-lysophosphatidylethanolamine + H2O
glycerophosphoethanolamine + palmitate
show the reaction diagram
Cryptococcus gattii
-
20% of the activity with 1-palmitoyl lysophosphatidylcholine, LPL1
-
-
?
1-palmitoyl-sn-glycero-3-phosphocholine + H2O
?
show the reaction diagram
-
-
-
?
1-palmitoyl-sn-glycero-3-phosphocholine + H2O
glycerophosphocholine + palmitate
show the reaction diagram
-
-
?
1-palmitoyl-sn-glycero-3-phosphocholine + H2O
palmitic acid + glycero-3-phosphocholine
show the reaction diagram
1-palmitoyl-sn-glycero-3-phosphoethanolamine + H2O
palmitic acid + glycero-3-phosphoethanolamine
show the reaction diagram
1-palmitoyl-sn-glycero-3-phosphoserine + H2O
glycerophosphoserine + palmitic acid
show the reaction diagram
1-palmitoyl-sn-glycerol + H2O
palmitic acid + glycerol
show the reaction diagram
-
-
-
-
?
1-stearoyl-2-arachidonoyl-sn-glycerol
?
show the reaction diagram
-
-
-
-
?
1-stearoyl-glycerophosphocholine + H2O
stearate + glycerophosphocholine
show the reaction diagram
-
-
-
-
?
1-stearoyl-sn-glycero-3-phosphocholine + H2O
stearic acid + glycerophosphorylcholine
show the reaction diagram
1-stearoyl-sn-glycero-3-phosphoethanolamine + H2O
stearic acid + glycero-3-phosphoethanolamine
show the reaction diagram
2,3-dioleoylglycerol + H2O
?
show the reaction diagram
-
-
-
-
?
2,3-dipalmitoyl-sn-glycero-1-phosphocholine + H2O
monopalmitoyl-sn-glycero-1-phosphocholine + palmitic acid
show the reaction diagram
2-acylglycerophosphocholine + H2O
fatty acid + glycerylphosphocholine
show the reaction diagram
2-acylglycerophosphoethanolamine + H2O
fatty acid + glycerylphosphoethanolamine
show the reaction diagram
-
-
-
-
?
2-acylglycerophosphoglycerol + H2O
fatty acid + glcyerophosphoglycerol
show the reaction diagram
-
-
-
-
?
2-lysophosphatidylcholine + H2O
glycerophosphocholine + a carboxylate
show the reaction diagram
2-lysophosphatidylcholine + H2O
glycerophosphocholine + a fatty acid
show the reaction diagram
-
-
-
?
2-palmitoyl-sn-glycero-3-phosphocholine + H2O
palmitic acid + glycero-3-phosphocholine
show the reaction diagram
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
4-nitrophenyl caprylate + H2O
4-nitrophenol + caprylate
show the reaction diagram
-
-
-
?
4-nitrophenyl decanoate + H2O
4-nitrophenol + decanoate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl hexanoate + H2O
4-nitrophenol + hexanoate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl laurate + H2O
4-nitrophenol + laurate
show the reaction diagram
relative activity: 7.56%
-
-
?
4-nitrophenyl myristate + H2O
4-nitrophenol + myristate
show the reaction diagram
4-nitrophenyl palmitate + H2O
4-nitrophenol + palmitate
show the reaction diagram
4-nitrophenyl stearate + H2O
4-nitrophenol + stearate
show the reaction diagram
C10:0-glycero-3-phosphocholine + H2O
?
show the reaction diagram
-
rank order for lysophospholipase activity C12:0-GPC higher than C14:0-GPC, C10:0-GPC higher than C18:0-GPC, C18:1-GPC, and C18:2-GPC higher than C8:0-GPC
-
-
?
C12:0-glycero-3-phosphocholine + H2O
?
show the reaction diagram
-
rank order for lysophospholipase activity C12:0-GPC higher than C14:0-GPC, C10:0-GPC higher than C18:0-GPC, C18:1-GPC, and C18:2-GPC higher than C8:0-GPC
-
-
?
C14:0-glycero-3-phosphocholine + H2O
?
show the reaction diagram
-
rank order for lysophospholipase activity C12:0-GPC higher than C14:0-GPC, C10:0-GPC higher than C18:0-GPC, C18:1-GPC, and C18:2-GPC higher than C8:0-GPC
-
-
?
C18:0-glycero-3-phosphocholine + H2O
?
show the reaction diagram
-
rank order for lysophospholipase activity C12:0-GPC higher than C14:0-GPC, C10:0-GPC higher than C18:0-GPC, C18:1-GPC, and C18:2-GPC higher than C8:0-GPC
-
-
?
C18:1-glycero-3-phosphocholine + H2O
?
show the reaction diagram
-
rank order for lysophospholipase activity C12:0-GPC higher than C14:0-GPC, C10:0-GPC higher than C18:0-GPC, C18:1-GPC, and C18:2-GPC higher than C8:0-GPC
-
-
?
C18:2-glycero-3-phosphocholine + H2O
?
show the reaction diagram
-
rank order for lysophospholipase activity C12:0-GPC higher than C14:0-GPC, C10:0-GPC higher than C18:0-GPC, C18:1-GPC, and C18:2-GPC higher than C8:0-GPC
-
-
?
C8:0-glycero-3-phosphocholine + H2O
?
show the reaction diagram
-
rank order for lysophospholipase activity C12:0-GPC higher than C14:0-GPC, C10:0-GPC higher than C18:0-GPC, C18:1-GPC, and C18:2-GPC higher than C8:0-GPC
-
-
?
dioleoylphosphatidylcholine + H2O
?
show the reaction diagram
Cryptococcus gattii
-
2% of the activity with dipalmitoylphosphatidylcholine
-
-
?
dioleoylphosphatidylethanolamine + H2O
?
show the reaction diagram
Cryptococcus gattii
-
11% of the activity with dipalmitoylphosphatidylcholine
-
-
?
dipalmitoylphosphatidylcholine + H2O
?
show the reaction diagram
Cryptococcus gattii
-
-
-
-
?
ghrelin + H2O
des-acyl ghrelin + n-octanoic acid
show the reaction diagram
-
-
-
-
?
lysophosphatidylcholine + H2O
glycerophosphorylcholine
show the reaction diagram
-
lysophospholipase A activity
-
-
?
lysophosphatidylcholine + H2O
glycerophosphorylcholine + unesterified fatty acid
show the reaction diagram
lysophosphatidylcholine + lysophosphatidylcholine
glycerophosphocholine + phosphatidylcholine
show the reaction diagram
lysophosphatidylethanolamine + H2O
?
show the reaction diagram
-
-
-
-
?
lysophosphatidylethanolamine + H2O
fatty acid + glycerylphosphoethanolamine
show the reaction diagram
lysophosphatidylglycerol + H2O
fatty acid + glycerol
show the reaction diagram
-
-
-
-
?
lysophosphatidylinositol + H2O
glycerophosphatidylinositol + a carboxylate
show the reaction diagram
-
78% of activity with 1-palmitoyl-lysophosphatidylcholine
-
?
monooleoylglycerol + H2O
oleic acid + glycerol
show the reaction diagram
-
-
-
-
?
monopalmitoylglycerol + H2O
palmitic acid + glycerol
show the reaction diagram
-
-
-
-
?
p-nitrophenyl acetate + H2O
p-nitrophenol + acetate
show the reaction diagram
p-nitrophenyl butyrate
p-nitrophenol + butyrate
show the reaction diagram
substrate activity assay
-
-
?
p-nitrophenyl palmitate
p-nitrophenol + palmitate
show the reaction diagram
substrate activity assay
-
-
?
palmitoyl-Gialpha1 + H2O
palmitic acid + Gialpha1
show the reaction diagram
-
thioesterase activity
-
?
palmitoyl-glycero-3-phosphocholine + H2O
glycerophosphocholine + palmitic acid
show the reaction diagram
-
-
-
-
?
palmitoyl-peptide + H2O
palmitate + peptide
show the reaction diagram
residue 3 to 14 of RGS4 protein with palmitoyl group attached at Cys12 of RGS4 protein
-
-
?
palmitoyl-SCoA + H2O
HS-CoA + palmitic acid
show the reaction diagram
-
-
-
?
palmitoyllysophosphatidylglycerol + H2O
glycerophosphoglycerol + palmitic acid
show the reaction diagram
-
-
-
-
?
phosphatidic acid + H2O
?
show the reaction diagram
phosphatidylcholine + H2O
lysophosphatidylcholine + a carboxylate
show the reaction diagram
phosphatidylcholine + H2O
lysophosphatidylcholine + glycerophosphorylcholine + a carboxylate
show the reaction diagram
phosphatidylcholine + H2O
lysophosphatidylcholine + glycerophosphorylcholine + a fatty acid
show the reaction diagram
-
-
-
?
phosphatidylethanolamine + H2O
lysophosphatidylethanolamine + glycerophosphorylethanolamine + a carboxylate
show the reaction diagram
phosphatidylethanolamine + H2O
lysophosphatidylethanolamine + glycerophosphorylethanolamine + a fatty acid
show the reaction diagram
-
-
-
?
phosphatidylglycerol + H2O
lysophosphatidylglycerol + a carboxylate
show the reaction diagram
-
94.2% of activity with 1,2-dipalmitoylphosphatidylcholine
-
?
phosphatidylinositol + H2O
lysophophatidylinositol + a carboxylate
show the reaction diagram
phosphatidylinositol + H2O
lysophosphatidylinositol + glycerophosphorylinositol + a carboxylate
show the reaction diagram
phosphatidylserine + H2O
lysophosphatidylserine + glycerophosphorylserine + a carboxylate
show the reaction diagram
phosphatidylserine + H2O
lysophosphatidylserine + glycerophosphorylserine + a fatty acid
show the reaction diagram
-
-
-
?
platelet activating factor + H2O
platelet activating factor + a carboxylate
show the reaction diagram
-
8.9% of activity with 1,2-dipalmitoylphosphatidylcholine
-
?
sphingomyelin + H2O
?
show the reaction diagram
Cryptococcus gattii
-
3% of the activity with dipalmitoylphosphatidylcholine
-
-
?
triacetin + H2O
?
show the reaction diagram
-
weak activity
-
-
?
tributyrin + H2O
?
show the reaction diagram
-
-
-
-
?
additional information
?
-
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
1-acyl-2-lysophosphatidycholine + H2O
fatty acid + glycerophosphocholine
show the reaction diagram
Q9U8F2
-
-
-
?
1-monopalmitoyllysophosphatidylglycerol + H2O
glycerophosphoglycerol + palmitic acid
show the reaction diagram
Q8GNM7
-
-
?
1-palmitoyl-2-lysophosphatidylcholine + H2O
glycerophosphocholine + palmitic acid
show the reaction diagram
-
-
-
?
1-palmitoyl-sn-glycero-3-phosphocholine + H2O
glycerophosphocholine + palmitate
show the reaction diagram
Q8GNM7
-
-
?
2-lysophosphatidylcholine + H2O
glycerophosphocholine + a carboxylate
show the reaction diagram
lysophosphatidylcholine + H2O
glycerophosphorylcholine
show the reaction diagram
-
lysophospholipase A activity
-
-
?
phosphatidylcholine + H2O
lysophosphatidylcholine + a carboxylate
show the reaction diagram
additional information
?
-
METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
CaCl2
Cryptococcus gattii
-
10 mM, 22% inhibition of phospholipase B activity, slight activation of lysophospholipase activity, to 8% at pH 5.0 and 4% at pH 7.0
Co2+
pH 8.0, activates
CoCl2
-
10 mM, stimulates
CuSO4
-
10 mM, stimulates
Hg2+
significantly inhibits enzyme activity
HgCl2
-
10 mM, stimulates
K3Fe(CN)6
-
activates
MgCl2
-
10 mM, stimulates
Mn2+
pH 8.0, activates
MnCl2
-
10 mM, stimulates
NiSO4
-
10 mM, stimulates
ZnCl2
-
10 mM, stimulates
additional information