Disease on EC 2.8.2.20 - protein-tyrosine sulfotransferase
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Atherosclerosis
Lack of Tyrosylprotein Sulfotransferase Activity in Hematopoietic Cells Drastically Attenuates Atherosclerosis in Ldlr-/- Mice.
Colorectal Neoplasms
Genetic variation in microRNA-binding site and prognosis of patients with colorectal cancer.
Congenital Hypothyroidism
Identifying quantitative trait loci affecting resistance to congenital hypothyroidism in 129/SvJcl strain mice.
Dwarfism
A mutation in Tpst2 encoding tyrosylprotein sulfotransferase causes dwarfism associated with hypothyroidism.
Dwarfism
Female infertility in grt mice is caused by thyroid hormone deficiency, not by insufficient TPST2 activity in the reproductive organs.
Dwarfism
Identifying quantitative trait loci affecting resistance to congenital hypothyroidism in 129/SvJcl strain mice.
Epilepsy
Isolation and expression profiling of genes upregulated in bone marrow-derived mononuclear cells of rheumatoid arthritis patients.
Herpes Zoster
Mice expressing aberrant sperm-specific protein PMIS2 produce normal-looking but fertilization-incompetent spermatozoa.
Hypothyroidism
A mutation in Tpst2 encoding tyrosylprotein sulfotransferase causes dwarfism associated with hypothyroidism.
Hypothyroidism
Early postnatal pulmonary failure and primary hypothyroidism in mice with combined TPST-1 and TPST-2 deficiency.
Hypothyroidism
Salivary Gland Hypofunction in tyrosylprotein sulfotransferase-2 Knockout Mice Is Due to Primary Hypothyroidism.
Infections
Genetic variations in the host dependency factors ALCAM and TPST2 impact HIV-1 disease progression.
Infertility
Detection and purification of tyrosine-sulfated proteins using a novel anti-sulfotyrosine monoclonal antibody.
Infertility
Female infertility in grt mice is caused by thyroid hormone deficiency, not by insufficient TPST2 activity in the reproductive organs.
Infertility, Female
Female infertility in grt mice is caused by thyroid hormone deficiency, not by insufficient TPST2 activity in the reproductive organs.
Infertility, Male
Lack of Tyrosylprotein Sulfotransferase-2 Activity Results in Altered Sperm-Egg Interactions and Loss of ADAM3 and ADAM6 in Epididymal Sperm.
Infertility, Male
Targeted disruption of tyrosylprotein sulfotransferase-2, an enzyme that catalyzes post-translational protein tyrosine O-sulfation, causes male infertility.
Lung Neoplasms
Tyrosylprotein sulfotransferase 1 expression is negatively correlated with c?Met and lymph node metastasis in human lung cancer.
Lymphatic Metastasis
Tyrosylprotein sulfotransferase 1 expression is negatively correlated with c?Met and lymph node metastasis in human lung cancer.
Nasopharyngeal Carcinoma
Tyrosylprotein sulfotransferase-1 and tyrosine sulfation of chemokine receptor 4 are induced by epstein-barr virus encoded latent membrane protein 1 and associated with the metastatic potential of human nasopharyngeal carcinoma.
Neoplasm Metastasis
Tyrosylprotein sulfotransferase 1 expression is negatively correlated with c?Met and lymph node metastasis in human lung cancer.
Neoplasm Metastasis
Tyrosylprotein sulfotransferase-1 and tyrosine sulfation of chemokine receptor 4 are induced by epstein-barr virus encoded latent membrane protein 1 and associated with the metastatic potential of human nasopharyngeal carcinoma.
Pancreatitis, Chronic
Sequence analysis of the human tyrosylprotein sulfotransferase-2 gene in subjects with chronic pancreatitis.
Pheochromocytoma
Tyrosine-O-sulfated proteins of PC12 pheochromocytoma cells and their sulfation by a tyrosylprotein sulfotransferase.
protein-tyrosine sulfotransferase deficiency
Early postnatal pulmonary failure and primary hypothyroidism in mice with combined TPST-1 and TPST-2 deficiency.
Shwachman-Diamond Syndrome
Fine mapping of the locus for Shwachman-Diamond syndrome at 7q11, identification of shared disease haplotypes, and exclusion of TPST1 as a candidate gene.
Thyroid Dysgenesis
Identifying quantitative trait loci affecting resistance to congenital hypothyroidism in 129/SvJcl strain mice.
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