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Reference on EC 2.8.1.2 - 3-mercaptopyruvate sulfurtransferase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Scott, E.M.; Wright, R.C.
Identity of beta-mercaptopyruvate sulfurtransferase and rhodanese in human erythrocytes
Biochem. Biophys. Res. Commun.
97
1334-1338
1980
Homo sapiens
Manually annotated by BRENDA team
Wrobel, M.; Frendo, J.
Comparison of some molecular and catalytic properties of mitochondrial and cytosolic rhodanese and mercaptopyruvate sulphurtransferase from frog (Rana temporaria) liver
Bull. Pol. Acad. Sci. Biol. Sci.
32
303-313
1984
Rana temporaria
-
Manually annotated by BRENDA team
Van den Hamer, C.J.A.; morell, A.G.; Scheinberg, I.H.
A study of the cooper content of beta-mercaptopyruvate trans-sulfurase
J. Biol. Chem.
242
2514-2516
1967
Rattus norvegicus
Manually annotated by BRENDA team
Vachek, H.; Wood, J.L.
Purification and properties of mercaptopyruvate sulfur transferase of Escherichia coli
Biochim. Biophys. Acta
258
133-146
1972
Escherichia coli
Manually annotated by BRENDA team
Wlodek, L.; Ostrowski, W.S.
3-Mercaptopyruvate sulphurtransferase from rat erythrocytes
Acta Biochim. Pol.
29
121-133
1982
Rattus norvegicus
Manually annotated by BRENDA team
Kasperczyk, H.; Koj, A.; Wasylewski, Z.
Similarity of some molecular and catalytic parameters of mitochondrial and cytosolic mercaptopyruvate sulfurtransferase from rat liver
Bull. Acad. Pol. Sci. Biol. Sci.
25
7-13
1977
Rattus norvegicus
Manually annotated by BRENDA team
Jarabak, R.
3-Mercaptopyruvate sulfurtransferase
Methods Enzymol.
77
291-297
1981
Bos taurus
Manually annotated by BRENDA team
Jarabak, R.; Westley, J.
3-Mercaptopyruvate sulfurtransferase: rapid equilibrium-ordered mechanism with cyanide as the acceptor substrate
Biochemistry
19
900-904
1980
Bos taurus
Manually annotated by BRENDA team
Koj, A.; Frendo, J.; Wojtczak, L.
Subcellular distribution and intramitochondrial localization of three sulfurtransferases in rat liver
FEBS Lett.
57
42-46
1975
Rattus norvegicus, Rattus norvegicus Wistar
Manually annotated by BRENDA team
Jarabak, R.; Westley, J.
Steady-state kinetics of 3-mercaptopyruvate sulfurtransferase from bovine kidney
Arch. Biochem. Biophys.
185
458-465
1978
Bos taurus
Manually annotated by BRENDA team
Taniguchi, T.; Kimura, T.
Role of 3-mercaptopyruvate sulfurtransferase in the formation of the iron-sulfur chromophore of adrenal ferredoxin
Biochim. Biophys. Acta
364
284-295
1974
Bos taurus
Manually annotated by BRENDA team
Alphey, M.S.; Williams, R.A.; Mottram, J.C.; Coombs, G.H.; Hunter, W.N.
The crystal structure of Leishmania major 3-mercaptopyruvate sulfurtransferase. A three-domain architecture with a serine protease-like triad at the active site
J. Biol. Chem.
278
48219-48227
2003
Leishmania major
Manually annotated by BRENDA team
Frendo, J.; Wrobel, M.; Was, K.
3-Mercaptopyruvate sulfurtransferase and rhodanese activities in human myometrium and leiomyomas of the uterus
Nowotwory J. Oncol.
52
123-125
2002
Homo sapiens
-
Manually annotated by BRENDA team
Meyer, T.; Burow, M.; Bauer, M.; Papenbrock, J.
Arabidopsis sulfurtransferases: investigation of their function during senescence and in cyanide detoxification
Planta
217
1-10
2003
Arabidopsis thaliana
Manually annotated by BRENDA team
Nagahara, N.; Ito, T.; Kitamura, H.; Nishino, T.
Tissue and subcellular distribution of mercaptopyruvate sulfurtransferase in the rat: confocal laser fluorescence and immunoelectron microscopic studies combined with biochemical analysis
Histochem. Cell Biol.
110
243-250
1998
Rattus norvegicus
Manually annotated by BRENDA team
Magahara, N.; Ito, T.; Minami, M.
Mercaptopyruvate sulfurtransferase as a defense against cyanide toxication: molecular properties and mode of detoxification
Histol. Histopathol.
14
1277-1286
1999
Rattus norvegicus
Manually annotated by BRENDA team
Magahara, N.; Nishino, T.
Role of amino acid residues in the active site of rat liver mercaptopyruvate sulfurtransferase. CDNA cloning, overexpression, and site-directed mutagenesis
J. Biol. Chem.
271
27395-27401
1996
Rattus norvegicus (P97532)
Manually annotated by BRENDA team
Magahara, N.; Okazaki, T.; Nishino, T.
Cytosolic mercaptopyruvate sulfurtransferase is evolutionarily related to mitochondrial rhodanese. Striking similarity in active site amino acid sequence and the increase in the mercaptopyruvate sulfurtransferase activity of rhodanese by site-directed mutagenesis
J. Biol. Chem.
270
16230-16235
1995
Rattus norvegicus, Rattus norvegicus Wistar
Manually annotated by BRENDA team
Makamura, T.; Yamaguchi, Y.; Sano, H.
Plant mercaptopyruvate sulfurtransferases: molecular cloning, subcellular localization and enzymatic activities
Eur. J. Biochem.
267
5621-5630
2000
Arabidopsis thaliana (Q24JL3)
Manually annotated by BRENDA team
Porter, D.W.; Baskin, S.I.
Specificity studies of 3-mercaptopyruvate sulfurtransferase
J. Biochem. Toxicol.
10
287-292
1995
Bos taurus
Manually annotated by BRENDA team
Porter, D.W.; Baskin, S.I.
The effect of three alpha-keto acids on 3-mercaptopyruvate sulfurtransferase activity
J. Biochem. Toxicol.
11
45-50
1996
Bos taurus
Manually annotated by BRENDA team
Spallarossa, A.; Forlani, F.; Carpen, A.; Armirotti, A.; Pagani, S.; Bolognesi, M.; Bordo, D.
The "rhodanese" fold and catalytic mechanism of 3-mercaptopyruvate sulfurtransferases: Crystal structure of SseA from Escherichia coli
J. Mol. Biol.
335
583-593
2004
Escherichia coli (P31142)
Manually annotated by BRENDA team
Williams, R.A.; Kelly, S.M.; Mottram, J.C.; Coombs, G.H.
3-Mercaptopyruvate sulfurtransferase of Leishmania contains an unusual C-terminal extension and is involved in thioredoxin and antioxidant metabolism
J. Biol. Chem.
278
1480-1486
2003
Leishmania major (Q7K9G0), Leishmania major, Leishmania mexicana (Q8T381), Leishmania mexicana
Manually annotated by BRENDA team
Nagahara, N.; Sawada, N.; Nakagawa, T.
Affinity labeling of a catalytic site, cysteine(247), in rat mercaptopyruvate sulfurtransferase by chloropyruvate as an analog of a substrate
Biochimie
86
723-729
2004
Rattus norvegicus
Manually annotated by BRENDA team
Nagahara, N.; Katayama, A.
Post-translational regulation of mercaptopyruvate sulfurtransferase via a low redox potential cysteine-sulfenate in the maintenance of redox homeostasis
J. Biol. Chem.
280
34569-34576
2005
Rattus norvegicus
Manually annotated by BRENDA team
Wrobel, M.; Jurkowska, H.
Menadione effect on L-cysteine desulfuration in U373 cells
Acta Biochim. Pol.
54
407-411
2007
Homo sapiens
Manually annotated by BRENDA team
Iciek, M.; Marcinek, J.; Mleczko, U.; Wlodek, L.
Selective effects of diallyl disulfide, a sulfane sulfur precursor, in the liver and Ehrlich ascites tumor cells
Eur. J. Pharmacol.
569
1-7
2007
Mus musculus
Manually annotated by BRENDA team
Nagahara, N.; Yoshii, T.; Abe, Y.; Matsumura, T.
Thioredoxin-dependent enzymatic activation of mercaptopyruvate sulfurtransferase. An intersubunit disulfide bond serves as a redox switch for activation
J. Biol. Chem.
282
1561-1569
2007
Rattus norvegicus, Rattus norvegicus (P97532)
Manually annotated by BRENDA team
Billaut-Laden, I.; Rat, E.; Allorge, D.; Crunelle-Thibaut, A.; Cauffiez, C.; Chevalier, D.; Lo-Guidice, J.M.; Broly, F.
Evidence for a functional genetic polymorphism of the human mercaptopyruvate sulfurtransferase (MPST), a cyanide detoxification enzyme
Toxicol. Lett.
165
101-111
2006
Homo sapiens
Manually annotated by BRENDA team
Wrobel, M.; Lewandowska, I.; Bronowicka-Adamska, P.; Paszewski, A.
The level of sulfane sulfur in the fungus Aspergillus nidulans wild type and mutant strains
Amino Acids
37
565-571
2008
Aspergillus nidulans
Manually annotated by BRENDA team
Shibuya, N.; Tanaka, M.; Yoshida, M.; Ogasawara, Y.; Togawa, T.; Ishii, K.; Kimura, H.
3-Mercaptopyruvate sulfurtransferase produces hydrogen sulfide and bound sulfane sulfur in the brain
Antioxid. Redox Signal.
11
703-714
2009
Mus musculus (Q99J99)
Manually annotated by BRENDA team
Nagahara, N.
A novel mercaptopyruvate sulfurtransferase thioredoxin-dependent redox-sensing molecular switch: a mechanism for the maintenance of cellular redox equilibrium
Mini Rev. Med. Chem.
8
585-589
2008
Rattus norvegicus (P97532)
Manually annotated by BRENDA team
Shibuya, N.; Mikami, Y.; Kimura, Y.; Nagahara, N.; Kimura, H.
Vascular endothelium expresses 3-mercaptopyruvate sulfurtransferase and produces hydrogen sulfide
J. Biochem.
146
623-626
2009
Rattus norvegicus
Manually annotated by BRENDA team
Westrop, G.D.; Georg, I.; Coombs, G.H.
The mercaptopyruvate sulfurtransferase of Trichomonas vaginalis links cysteine catabolism to the production of thioredoxin persulfide
J. Biol. Chem.
284
33485-33494
2009
Trichomonas vaginalis
Manually annotated by BRENDA team
Jurkowska, H.; Placha, W.; Nagahara, N.; Wrobel, M.
The expression and activity of cystathionine-gamma-lyase and 3-mercaptopyruvate sulfurtransferase in human neoplastic cell lines
Amino Acids
41
151-158
2011
Homo sapiens
Manually annotated by BRENDA team
Nagahara, N.
Regulation of mercaptopyruvate sulfurtransferase activity via intrasubunit and intersubunit redox-sensing switches
Antioxid. Redox Signal.
19
1792-1802
2013
Mus musculus, Rattus norvegicus
Manually annotated by BRENDA team
Mikami, Y.; Shibuya, N.; Ogasawara, Y.; Kimura, H.
Hydrogen sulfide is produced by cystathionine gamma-lyase at the steady-state low intracellular Ca2+ concentrations
Biochem. Biophys. Res. Commun.
431
131-135
2013
Rattus norvegicus
Manually annotated by BRENDA team
Modis, K.; Asimakopoulou, A.; Coletta, C.; Papapetropoulos, A.; Szabo, C.
Oxidative stress suppresses the cellular bioenergetic effect of the 3-mercaptopyruvate sulfurtransferase/hydrogen sulfide pathway
Biochem. Biophys. Res. Commun.
433
401-407
2013
Mus musculus
Manually annotated by BRENDA team
Mikami, Y.; Shibuya, N.; Kimura, Y.; Nagahara, N.; Ogasawara, Y.; Kimura, H.
Thioredoxin and dihydrolipoic acid are required for 3-mercaptopyruvate sulfurtransferase to produce hydrogen sulfide
Biochem. J.
439
479-485
2011
Mus musculus
Manually annotated by BRENDA team
Tanizawa, K.
Production of H2S by 3-mercaptopyruvate sulphurtransferase
J. Biochem.
149
357-359
2011
Homo sapiens
Manually annotated by BRENDA team
Yadav, P.K.; Yamada, K.; Chiku, T.; Koutmos, M.; Banerjee, R.
Structure and kinetic analysis of H2S production by human mercaptopyruvate sulfurtransferase
J. Biol. Chem.
288
20002-20013
2013
Homo sapiens (P25325), Homo sapiens
Manually annotated by BRENDA team
Modis, K.; Coletta, C.; Erdelyi, K.; Papapetropoulos, A.; Szabo, C.
Intramitochondrial hydrogen sulfide production by 3-mercaptopyruvate sulfurtransferase maintains mitochondrial electron flow and supports cellular bioenergetics
FASEB J.
27
601-611
2013
Mus musculus (Q99J99), Mus musculus
Manually annotated by BRENDA team
Singh, P.; Rao, P.; Bhattacharya, R.
Dose and time-dependent effects of cyanide on thiosulfate sulfurtransferase, 3-mercaptopyruvate sulfurtransferase, and cystathionine lambda-lyase activities
J. Biochem. Mol. Toxicol.
27
499-507
2013
Mus musculus (Q99J99)
Manually annotated by BRENDA team
Fraesdorf, B.; Radon, C.; Leimkuehler, S.
Characterization and interaction studies of two isoforms of the dual localized 3-mercaptopyruvate sulfurtransferase TUM1 from humans
J. Biol. Chem.
289
34543-34556
2014
Homo sapiens (P25325), Homo sapiens
Manually annotated by BRENDA team
Miyamoto, R.; Otsuguro, K.; Yamaguchi, S.; Ito, S.
Contribution of cysteine aminotransferase and mercaptopyruvate sulfurtransferase to hydrogen sulfide production in peripheral neurons
J. Neurochem.
130
29-40
2014
Rattus norvegicus (P97532)
Manually annotated by BRENDA team
Nagahara, N.; Nagano, M.; Ito, T.; Suzuki, H.
Redox regulation of mammalian 3-mercaptopyruvate sulfurtransferase
Methods Enzymol.
554
229-254
2015
Rattus norvegicus (P97532)
Manually annotated by BRENDA team
Zhao, H.; Chan, S.J.; Ng, Y.K.; Wong, P.T.
Brain 3-mercaptopyruvate sulfurtransferase (3MST): cellular localization and downregulation after acute stroke
PLoS ONE
8
e67322
2013
Rattus norvegicus (P97532)
Manually annotated by BRENDA team
Nagahara, N.; Nagano, M.; Ito, T.; Shimamura, K.; Akimoto, T.; Suzuki, H.
Antioxidant enzyme, 3-mercaptopyruvate sulfurtransferase-knockout mice exhibit increased anxiety-like behaviors: a model for human mercaptolactate-cysteine disulfiduria
Sci. Rep.
3
1986
2013
Mus musculus (Q99J99)
Manually annotated by BRENDA team
Kimura, Y.; Toyofuku, Y.; Koike, S.; Shibuya, N.; Nagahara, N.; Lefer, D.; Ogasawara, Y.; Kimura, H.
Identification of H2S3 and H2S produced by 3-mercaptopyruvate sulfurtransferase in the brain
Sci. Rep.
5
14774
2015
Mus musculus (Q99J99)
Manually annotated by BRENDA team
Lec, J.; Boutserin, S.; Mazon, H.; Mulliert, G.; Boschi-Muller, S.; Talfournier, F.
Unraveling the mechanism of cysteine persulfide formation catalyzed by 3-mercaptopyruvate sulfurtransferases
ACS Catal.
8
2049-2059
2018
Escherichia coli, Homo sapiens (P25325), Escherichia coli DH5alpha
-
Manually annotated by BRENDA team
Nagahara, N.; Koike, S.; Nirasawa, T.; Kimura, H.; Ogasawara, Y.
Alternative pathway of H2S and polysulfides production from sulfurated catalytic-cysteine of reaction intermediates of 3-mercaptopyruvate sulfurtransferase
Biochem. Biophys. Res. Commun.
496
648-653
2018
Rattus norvegicus (P97532)
Manually annotated by BRENDA team
Panagaki, T.; Randi, E.B.; Szabo, C.
Role of 3-mercaptopyruvate sulfurtransferase in the regulation of proliferation and cellular bioenergetics in human Down syndrome fibroblasts
Biomolecules
10
653
2020
Homo sapiens (P25325), Homo sapiens
Manually annotated by BRENDA team
Abdollahi Govar, A.; Toero, G.; Szaniszlo, P.; Pavlidou, A.; Bibli, S.I.; Thanki, K.; Resto, V.A.; Chao, C.; Hellmich, M.R.; Szabo, C.; Papapetropoulos, A.; Modis, K.
3-Mercaptopyruvate sulfurtransferase supports endothelial cell angiogenesis and bioenergetics
Br. J. Pharmacol.
177
866-883
2020
Homo sapiens (P25325), Homo sapiens
Manually annotated by BRENDA team
Zuhra, K.; Tome, C.S.; Masi, L.; Giardina, G.; Paulini, G.; Malagrino, F.; Forte, E.; Vicente, J.B.; Giuffre, A.
N-acetylcysteine serves as substrate of 3-mercaptopyruvate sulfurtransferase and stimulates sulfide metabolism in colon cancer cells
Cells
8
828
2019
Homo sapiens (P25325), Homo sapiens
Manually annotated by BRENDA team
Wang, J.; Guo, X.; Li, H.; Qi, H.; Qian, J.; Yan, S.; Shi, J.; Niu, W.
Hydrogen sulfide from cysteine desulfurase, not 3-mercaptopyruvate sulfurtransferase, contributes to sustaining cell growth and bioenergetics in E. coli under anaerobic conditions
Front. Microbiol.
10
2357
2019
Escherichia coli, Escherichia coli BW25113
Manually annotated by BRENDA team
Bronowicka-Adamska, P.; Bentke, A.; Lasota, M.; Wrobel, M.
Effect of S-allyl-L-cysteine on MCF-7 cell line 3-mercaptopyruvate sulfurtransferase/sulfane sulfur system, viability and apoptosis
Int. J. Mol. Sci.
21
1090
2020
Homo sapiens (P25325), Homo sapiens
Manually annotated by BRENDA team
Yadav, P.; Vitvitsky, V.; Carballal, S.; Seravalli, J.; Banerjee, R.
Thioredoxin regulates human mercaptopyruvate sulfurtransferase at physiologically-relevant concentrations
J. Biol. Chem.
295
6299-6310
2020
Homo sapiens (P25325), Homo sapiens, Mus musculus (Q99J99), Mus musculus
Manually annotated by BRENDA team
Tomita, M.; Nagahara, N.; Ito, T.
Expression of 3-mercaptopyruvate sulfurtransferase in the mouse
Molecules
21
1707
2016
Mus musculus (Q99J99), Mus musculus
Manually annotated by BRENDA team
Hoefler, S.; Lorenz, C.; Busch, T.; Brinkkoetter, M.; Tohge, T.; Fernie, A.R.; Braun, H.P.; Hildebrandt, T.M.
Dealing with the sulfur part of cysteine four enzymatic steps degrade l-cysteine to pyruvate and thiosulfate in Arabidopsis mitochondria
Physiol. Plant.
157
352-366
2016
Arabidopsis thaliana (O64530)
Manually annotated by BRENDA team
Kimura, Y.; Koike, S.; Shibuya, N.; Lefer, D.; Ogasawara, Y.; Kimura, H.
3-Mercaptopyruvate sulfurtransferase produces potential redox regulators cysteine- and glutathione-persulfide (Cys-SSH and GSSH) together with signaling molecules H2S2, H2S3 and H2S
Sci. Rep.
7
10459
2017
Mus musculus (Q99J99)
Manually annotated by BRENDA team
Hanaoka, K.; Sasakura, K.; Suwanai, Y.; Toma-Fukai, S.; Shimamoto, K.; Takano, Y.; Shibuya, N.; Terai, T.; Komatsu, T.; Ueno, T.; Ogasawara, Y.; Tsuchiya, Y.; Watanabe, Y.; Kimura, H.; Wang, C.; Uchiyama, M.; Kojima, H.; Okabe, T.; Urano, Y.; Shimizu, T.; Nagano, T.
Discovery and mechanistic characterization of selective inhibitors of H2S-producing enzyme 3-mercaptopyruvate sulfurtransferase (3MST) targeting active-site cysteine persulfide
Sci. Rep.
7
40227
2017
Homo sapiens (P25325)
Manually annotated by BRENDA team
Meza, A.; Cambui, C.; Moreno, A.; Fessel, M.; Balan, A.
Mycobacterium tuberculosis CysA2 is a dual sulfurtransferase with activity against thiosulfate and 3-mercaptopyruvate and interacts with mammalian cells
Sci. Rep.
9
16791
2019
Mycobacterium tuberculosis (P9WHF9), Mycobacterium tuberculosis H37Rv (P9WHF9)
Manually annotated by BRENDA team