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Information on EC 2.8.1.10 - thiazole synthase and Organism(s) Escherichia coli and UniProt Accession P30139

for references in articles please use BRENDA:EC2.8.1.10
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EC Tree
     2 Transferases
         2.8 Transferring sulfur-containing groups
             2.8.1 Sulfurtransferases
                2.8.1.10 thiazole synthase
IUBMB Comments
H2S can provide the sulfur in vitro. Part of the pathway for thiamine biosynthesis.
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This record set is specific for:
Escherichia coli
UNIPROT: P30139
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Word Map
The taxonomic range for the selected organisms is: Escherichia coli
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Synonyms
thiazole synthase, thiamine thiazole synthase, more
PATHWAY SOURCE
PATHWAYS
-
-, -
SYSTEMATIC NAME
IUBMB Comments
1-deoxy-D-xylulose 5-phosphate:thiol sulfurtransferase
H2S can provide the sulfur in vitro. Part of the pathway for thiamine biosynthesis.
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
additional information
?
-
ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
NADPH
-
strong stimulation
S-adenosylmethionine
-
strong stimulation
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
UniProt
Manually annotated by BRENDA team
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Leonardi, R.; Roach, P.L.
Thiamine biosynthesis in Escherichia coli: in vitro reconstitution of the thiazole synthase activity
J. Biol. Chem.
279
17054-17062
2004
Escherichia coli
Manually annotated by BRENDA team
Kriek, M.; Martins, F.; Leonardi, R.; Fairhurst, S.A.; Lowe, D.J.; Roach, P.L.
Thiazole synthase from Escherichia coli: an investigation of the substrates and purified proteins required for activity in vitro
J. Biol. Chem.
282
17413-17423
2007
Escherichia coli (P30139), Escherichia coli
Manually annotated by BRENDA team