Reference on EC 2.7.8.15 - UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Sharma, C.B.; Lehle, L.; Tanner, W.
Solubilization and characterization of the initial enzymes of the dolichol pathway from yeast
Eur. J. Biochem.
126
319-325
1982
Saccharomyces cerevisiae, Saccharomyces cerevisiae X2180-1A
Villemez, C.L.; Carlo, P.L.
Properties of a soluble polyprenyl phosphate. UDP-D-N-acetylglucosamine N-acetylglucosamine-1-phosphate transferase
J. Biol. Chem.
255
8174-8178
1980
Acanthamoeba castellanii
Shailubhai, K.; Dong-Yu, B.; Saxena, E.S.; Vijay, I.K.
Purification and characterization of UDP-N-acetyl-D-glucosamine:dolichol phosphate N-acetyl-D-glucosamine-1-phosphate transferase involved in the biosynthesis of asparagine-linked glycoproteins in the mammary gland
J. Biol. Chem.
263
15964-15972
1988
Bos taurus
Kaushal, G.P.; Elbein, A.D.
Purification and properties of UDP-GlcNAc:dolichyl-phosphate GlcNAc-1-phosphate transferase. Activation and inhibition of the enzyme
J. Biol. Chem.
260
16303-16309
1985
Sus scrofa
Plouhar, P.L.; Bretthauer, R.K.
A phospholipid requirement for dolichol pyrophosphate N-acetylglucosamine synthesis in phospholipase A2-treated rat lung microsomes
J. Biol. Chem.
257
8907-8911
1982
Rattus norvegicus
Heifetz, A.; Keenan, R.W.; Elbein, A.D.
Mechanism of action of tunicamycin on the UDP-GlcNAc:dolichyl-phosphate Glc-NAc-1-phosphate transferase
Biochemistry
18
2186-2192
1979
Sus scrofa
Kaushal, G.P.; Elbein, A.D.
Properties of solubilized UDP-GlcNAc:dolichyl phosphate-GlcNAc-1-P-transferase from soybean cultured cells
Plant Physiol.
82
748-752
1986
Glycine max
Chandra, N.C.; Doody, M.B.; Bretthauer, R.K.
Specific lipids enhance the activity of UDP-GlcNAc: dolichol phosphate GlcNAc-1-phosphate transferase in rat liver endoplasmic reticulum membrane vesicles
Arch. Biochem. Biophys.
290
345-354
1991
Rattus norvegicus
Zeng, Y.; Elbein, A.D.
UDP-N-acetylglucosamine:dolichyl-phosphate N-acetylglucosamine-1-phosphate transferase is amplified in tunicamycin-resistant soybean cells
Eur. J. Biochem.
233
458-466
1995
Glycine max
Sorensen, T.K.; Dyer, P.S.; Fierro, F.; Laube, U.; Peberdy, J.F.
Characterisation of the gptA gene, encoding UDP N-acetylglucosamine: dolichol phosphate N-acetylglucosaminylphosphoryl transferase, from the filamentous fungus, Aspergillus niger
Biochim. Biophys. Acta
1619
89-97
2003
Aspergillus niger, Aspergillus niger N402
Kukuruzinska, M.A.; Lennon, K.
Diminished activity of the first N-glycosylation enzyme, dolichol-P-dependent N-acetylglucosamine-1-P transferase (GPT), gives rise to mutant phenotypes in yeast
Biochim. Biophys. Acta
1247
51-59
1995
Saccharomyces cerevisiae
Mota, O.M.; Huang, G.T.; Kukuruzinska, M.A.
Developmental regulation and tissue-specific expression of hamster dolichol-P-dependent N-acetylglucosamine-1-P transferase (GPT)
Biochem. Biophys. Res. Commun.
204
284-291
1994
Cricetulus griseus
Huang, G.T.; Lennon, K.; Kukuruzinska, M.A.
Characterization of multiple transcripts of the hamster dolichol-P-dependent N-acetylglucosamine-1-P transferase suggests functionally complex expression
Mol. Cell. Biochem.
181
97-106
1998
Cricetulus griseus
Scocca, J.R.; Krag, S.S.
Aspartic acid 252 and asparagine 185 are essential for activity of lipid N-acetylglucosaminylphosphate transferase
Glycobiology
7
1181-1191
1997
Cricetulus griseus
Wu, X.; Rush, J.S.; Karaoglu, D.; Krasnewich, D.; Lubinsky, M.S.; Waechter, C.J.; Gilmore, R.; Freeze, H.H.
Deficiency of UDP-GlcNAc: dolichol phosphate N-acetylglucosamine-1 phosphate transferase (DPAGT1) causes a novel congenital disorder of glycosylation type Ij
Hum. Mutat.
22
144-150
2003
Homo sapiens
Meissner, J.D.; Naumann, A.; Mueller, W.H.; Scheibe, R.J.
Regulation of UDP-N-acetylglucosamine:dolichyl-phosphate N-acetylglucosamine-1-phosphate transferase by retinoic acid in P19 cells
Biochem. J.
338
561-568
1999
Mus musculus
Zara, J.; Lehrman, M.A.
Role of the carboxyl terminus in stable expression of hamster UDP-GlcNAc:dolichol-P GlcNAc-1-P transferase
J. Biol. Chem.
269
19108-19115
1994
Cricetulus griseus
Rajput, B.; Ma, J.; Vijay, I.K.
Structure and organization of mouse GlcNAc-1-phosphate transferase gene
J. Biol. Chem.
269
9590-9597
1994
Mus musculus
Dan, N.; Middleton, R.B.; Lehrman, M.A.
Hamster UDP-N-acetylglucosamine:dolichol-P N acetylglucosamine-1-P transferase has multiple transmembrane spans and a critical cytosolic loop
J. Biol. Chem.
271
30717-30724
1996
Cricetulus griseus
Dan, N.; Lehrman, M.A.
Oligomerization of hamster UDP-GlcNAc:dolichol-P GlcNAc-1-P transferase, an enzyme with multiple transmembrane spans
J. Biol. Chem.
272
14214-14219
1997
Cricetulus griseus
Mendelsohn, R.D.; Helmerhorst, E.J.; Cipollo, J.F.; Kukuruzinska, M.A.
A hypomorphic allele of the first N-glycosylation gene, ALG7, causes mitochondrial defects in yeast
Biochim. Biophys. Acta
1723
33-44
2005
Saccharomyces cerevisiae
Gao, N.; Shang, J.; Lehrman, M.A.
Unexpected basis for impaired Glc3Man9GlcNAc2-P-P-dolichol biosynthesis by elevated expression of Glcnac-1-p transferase
Glycobiology
18
125-134
2007
Cricetulus griseus, Mesocricetus auratus
Plante, M.; Claveau, S.; Lepage, P.; Lavoie, E.M.; Brunet, S.; Roquis, D.; Morin, C.; Vezina, H.; Laprise, C.
Mucolipidosis II: a single causal mutation in the N-acetylglucosamine-1-phosphotransferase gene (GNPTAB) in a French Canadian founder population
Clin. Genet.
73
236-244
2008
Homo sapiens
Bretthauer, R.K.
Structure, expression, and regulation of UDP-GlcNAc: dolichol phosphate GlcNAc-1-phosphate transferase (DPAGT1)
Curr. Drug Targets
10
477-482
2009
Bos taurus, Cricetulus griseus, Homo sapiens, Mus musculus, Rattus norvegicus
Kim, H.S.; Kim, M.S.; Hwang, K.A.; Park, S.W.; Jeon, J.H.
The UDP-N-acetylglucosamine:dolichol phosphate-N-acetylglucosamine-phosphotransferase gene as a new selection marker for potato transformation
Biosci. Biotechnol. Biochem.
77
1589-1592
2013
Solanum tuberosum (G1FCL5), Solanum tuberosum
Kurosu, M.
Structure-based drug discovery by targeting N-glycan biosynthesis, dolichyl-phosphate N-acetylglucosaminephosphotransferase
Future Med. Chem.
11
927-933
2019
Homo sapiens (Q9H3H5)
Yuste-Checa, P.; Vega, A.I.; Martin-Higueras, C.; Medrano, C.; Gamez, A.; Desviat, L.R.; Ugarte, M.; Perez-Cerda, C.; Perez, B.
DPAGT1-CDG functional analysis of disease-causing pathogenic mutations and role of endoplasmic reticulum stress
PLoS ONE
12
e0179456
2017
Homo sapiens (Q9H3H5), Homo sapiens
Meyer, B.H.; Shams-Eldin, H.; Albers, S.V.
AglH, a thermophilic UDP-N-acetylglucosamine-1-phosphate dolichyl phosphate GlcNAc-1-phosphotransferase initiating protein N-glycosylation pathway in Sulfolobus acidocaldarius, is capable of complementing the eukaryal Alg7
Extremophiles
21
121-134
2017
Sulfolobus acidocaldarius (P39465), Sulfolobus acidocaldarius ATCC 33909 (P39465)
Kanaki, N.; Matsuda, A.; Dejima, K.; Murata, D.; Nomura, K.H.; Ohkura, T.; Gengyo-Ando, K.; Yoshina, S.; Mitani, S.; Nomura, K.
UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase is indispensable for oogenesis, oocyte-to-embryo transition, and larval development of the nematode Caenorhabditis elegans
Glycobiology
29
163-178
2019
Caenorhabditis elegans (Q9U1Z2), Caenorhabditis elegans
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